ABSTRACT
Ultraviolet light has a wide spectrum of effects on human skin depending on the wavelength. Ultraviolet light often used for therapy of psoriasis comprises of electromagnetic spectrum ranging from 200nm – 400nm. Phototherapy of psoriasis is frequently used in combination regimens to achieve higher clearance rates, longer disease-free intervals, and to reduce the patient`s cumulative radiation dose thereby lowering the carcinogenic risk. Phototherapy may be combined with topical or systemic agents. Topical agents most commonly used are anthralin, tar, vitamin D analogues and tazarotene. Among systemic agents, retinoids are the most widely used. Ultraviolet B wavelengths in the range of 300-313nm is more efficacious than conventional broad-band UV-B [Philips TL 40W/12 lamp] and causes greater remission of psoriatic lesions. 311nm narrow-band UV-B (TL-01) phototherapy is more effective and probably has no greater risk than conventional UV-B (TL-12) phototherapy in the treatment of psoriasis.
Subject(s)
Humans , Phototherapy/methods , Phototherapy/therapeutic use , Phototherapy/trends , Phototherapy/statistics & numerical data , Psoriasis/radiotherapy , Psoriasis/therapy , Retinoids/administration & dosage , Retinoids/therapeutic useSubject(s)
Humans , Retinoids/administration & dosage , Acne Vulgaris/complications , Dermatologic Agents , RosaceaABSTRACT
Se confirma la importante actividad terapéutica de 13.cRA y del IFNÓ-2a en el carcinoma de células escamosas del cervix sin tratamiento previo. Un resultado inesperado fue la toxicidad temprana de los agentes biológicos sobre la mucosa del colon cuando se combinan con radioterapia
Subject(s)
Adult , Humans , Female , Carcinoma, Squamous Cell/drug therapy , Carcinoma, Squamous Cell/radiotherapy , Carcinoma, Endometrioid , Drug Tolerance/radiation effects , Interferon-alpha/administration & dosage , Interferon-alpha/therapeutic use , Isotretinoin/administration & dosage , Isotretinoin/therapeutic use , Retinoids/administration & dosage , Retinoids/therapeutic use , Uterine Cervical Neoplasms/drug therapy , Uterine Cervical Neoplasms/radiotherapyABSTRACT
Loa autores refieren su experiencia en el tratamiento de dos casos severos de ictiosis (laminar y ampollar) con retinoide aromático (Ro 10-9359) por vía oral. Se destaca la importancia de este tipo de terapéutica, ya que el problema cutáneo de estos pacientes dificulta sus relaciones psicosociales