ABSTRACT
Abstract: We report an 80-year-old male patient with severe rheumatoid arthritis who was treated with tripterygium glycoside, an immunosuppressive agent made from the extract of a Chinese medicinal herb called Tripterygium wilfordii Hook F. The patient had no apparent skin lesions before the treatment, but he developed aggressive hyperkeratotic lesions with rapid progression after using tripterygium glycoside. He was repeatedly diagnosed with eczema, but treatment failed to achieve efficacy. Interestingly, a microscopic examination of the lesions revealed numerous scabies mites and eggs. Thus, we confirmed the diagnosis of Norwegian scabies infection. Treated with crotamiton 10% cream and 10% sulfur ointment for one month, the patient's clinical symptoms disappeared.
Subject(s)
Humans , Animals , Male , Aged, 80 and over , Arthritis, Rheumatoid/drug therapy , Scabies/chemically induced , Tripterygium/chemistry , Glycosides/adverse effects , Sarcoptes scabiei , Scabies/diagnosis , Plant Extracts/adverse effectsABSTRACT
La Sarna Noruega es una forma rara de escabiosis, ubicada en el extremo más severo del espectro de la infestación por el Sarcoptes scabiei. Se estudia una paciente que presenta placas verrugosas, grisáceas en dorso de manos y pies, pezones, pliegues inguinales, axilares y popliteo derecho, de 2 años de evolución, tiempo durante el cual recibó esteroides tópicos como tratamiento