1.
Braz. j. med. biol. res
;
20(6): 767-70, 1987. ilus
Article
in English
| LILACS
| ID: lil-77435
ABSTRACT
Two types inhibitors were prufied from Enterolobium contortisiliquum beans. The inhibitor of serine-proteinases inhibited trypasin (Ki = 5 nM) chymostrypsin (Ki = 10 nM) and plasma kallikrein, but not tissue kallikreins. The molecular weight is approximately 23 KDal and two polypeptide chains detected after reduction. The second inhibitor with activity directed against SH-proteinase was isolated by CM-papain-Sepharose. The molecular weight is approximately 60 KDal and only one polupeptide chain was detected after reduction. Papain (Ki = 0.6 nM) and bromelain are inhibited