ABSTRACT
El liquen plano hipertrófico generalizado es una enfermedad inflamatoria autolimitada, subaguda o crónica, de origen desconocido, que afecta la piel, las mucosas y los anexos. Clínicamente se caracteriza por pápulaspoligonales, pruriginosas, violáceas o grisáceas, que confluyen formando placas con superficie hiperqueratósica de aspecto verrugoso. Es extremadamente raro en niños y su incidencia mundial es menor al 1%. Comunicamos el caso clínico de un paciente en edad pediátrica con liquen plano hipertrófico generalizado, cuyo interés radica en la peculiar edad de aparición.
Generalized hypertrophic lichen planus is a self-limited subacute or chronic inflammatory disease of unknown etiology that affects the skin, mucous membranes and skin appendages. It is characterized by pruritic, polygonal, purple or grayish papules that converge to form hyperkeratotic plaques with a warty surface. It is extremely rare in children, with a global incidence less than 1%.We report the case of a pediatric patient with generalized hypertrophic lichen planus, the interest of the case lies in reporting the particular age of onset.
Subject(s)
Humans , Male , Child , Hand Dermatoses , Skin Diseases, Eczematous , Lichen Planus , Skin Diseases , Lower Extremity , HandABSTRACT
La colagenosis perforante reactiva es un trastorno de la piel poco frecuente, caracterizado por la eliminación transepidérmica de colágeno alterado a través de la epidermis. Existen dos tipos de la enfermedad: la forma hereditaria, que se manifiesta en la infancia, y la esporádica adquirida, que aparece en la edad adulta. Se presenta con pápulas pruriginosas que aumentan de tamaño. Estas pueden remitir espontáneamente, dejando áreas de hipo-hiperpigmentación o cicatrices. También es posible que ocurra el fenómeno de Koebner.Se comunica el caso de un paciente pediátrico con una colagenosis perforante reactiva. Esta publicación reviste importancia debido a que esta patología es extremadamente infrecuente.
Reactive perforating collagenosis is a rare skin disorder, characterized by the transepidermal elimination of altered collagen through the epidermis. There are two different types: the hereditary form that manifests in childhood, and the sporadic acquired one that appears in adulthood. It presents with pruritic papules that increase in size. They may remit spontaneously, leaving areas of hypo/hyperpigmentation or scars. It is also possible that the Koebner phenomenon occurs. We report one case of a pediatric patient with reactive perforating collagenosis. This publication has importance because this condition is extremely rare.
Subject(s)
Humans , Male , Adolescent , Skin Diseases, Eczematous , Collagen Diseases , Lower ExtremityABSTRACT
La alergia de contacto a fragancias constituye un problema clínico importante. Su frecuencia se estima de 1 a 2% en la población general y alrededor del 8% en los pacientes con eccema de contacto. La sensibilización a fragancias se encuentra entre las causas más comunes de dermatitis alérgica por contacto, después del níquel y de los conservantes. Han surgido nuevas sustancias de detección con el finde aumentar la capacidad de diagnóstico de alergia a los perfumes. Desde el año 2005, una novedosa mezcla de fragancia compuesta por seis sustanciasse ha comercializado para su introducción en la batería estándar de alérgenos.El alérgeno más frecuente en esta mezcla es el Carboxaldehído hidroxilo isohexylcyclohexene (HICC) (Lyral ®).Se comunican cuatro pacientes con reacción positiva a Lyral® que han sido relevantes en relación al cuadro clínico.Este estudio ilustra que la alergia de contacto a fragancias es común en los pacientes que sufren de dermatitis de contacto...
Subject(s)
Humans , Dermatitis, Contact/diagnosis , Skin Diseases , Skin Diseases, EczematousABSTRACT
Objetivo: Relatar o caso vivenciado na prática de enfermagem, no manejo de complicações de pele periestoma,e avaliar as mudanças clínicas obtidas após a utilização de protetores cutâneos. Relato de caso: O estudo foi desenvolvido em uma paciente estomizada de 57 anos, cuja pele periestoma apresentava extensa dermatite periestomal com aspecto brilhante, altamente exsudativa, irritativa e dolorosa, em que o dispositivo para estomia mantinha-se adaptado por menos de 24 horas. Conclusão: Após o manejo dos protetores cutâneos, houve evolução satisfatória em relação à lesão periestomal e no emocional, o que resultou no fechamento da ileostomia.
Objective: To report a case experienced in nursing practice regarding the management of peristomal skin complications, as well as to evaluate the clinical changes obtained after the use of skin protectors. Case report: this study was developed in a patient with stoma 57, whose skin had extensive peristomal dermatitis, glossy, highly exudative, irritating and painful, who had a device installed for ostomy adapted forless than 24 hours. Conclusion: After the management of skin protectors, there was satisfactory progress in relation to peristomal and emotional injury, which resulted in the closure of the ileostomy.
Subject(s)
Humans , Female , Middle Aged , Abdomen, Acute/complications , Abdomen, Acute/diagnosis , Skin Diseases, Eczematous/complications , Skin Diseases, Eczematous/rehabilitation , Peritoneal Stomata , Wounds and Injuries , Administration, Cutaneous , Skin Diseases, Eczematous/diagnosis , Epidemiology, Descriptive , Cutaneous Fistula/surgery , Skin AbsorptionABSTRACT
The prevalence of paediatric dermatoses has risen in Iraq from 33.5% in 1987 to 40.9% in 2010. The objective of this study was to document the pattern of dermatoses in Iraqi children attending the outpatient clinic of a teaching hospital in Baghdad, Iraq. We conducted a cross-sectional study of 663 children under the age of 12 years who attended fordermatological consultation during 2008. The study showed that the prevailing dermatoses were as follow: infectious [32.3%], eczematous [20,8%], pigmentary [17.8%], papulosquamous [14.2%], drug-induced [4.5%], nutritional deficiency [1.8%] and miscellaneous [8.6%]. The studied patterns of dermatoses were similar to that reported in other developing countries
Subject(s)
Humans , Male , Female , Hospitals, Teaching , Cross-Sectional Studies , Skin Diseases, Infectious/epidemiology , Skin Diseases, Eczematous/epidemiology , Pigmentation Disorders/epidemiologyABSTRACT
Atopic dermatitis (AD) is a common, chronic or chronically relapsing, severely pruritic, eczematous skin disease. AD is the second most frequently observed skin disease in dermatology clinics in Japan. Prevalence of childhood AD is 12-13% in mainland Japan; however, it is only half that (about 6%) in children from Ishigaki Island, Okinawa. Topical steroids and tacrolimus are the mainstay of treatment. However, the adverse effects and emotional fear of long-term use of topical steroids have induced a "topical steroid phobia" in patients throughout the world. Undertreatment can exacerbate facial/periocular lesions and lead to the development of atopic cataract and retinal detachment due to repeated scratching/rubbing/patting. Overcoming topical steroid phobia is a key issue for the successful treatment of AD through education, understanding and cooperation of patients and their guardians.
Subject(s)
Child , Humans , Cataract , Dermatitis, Atopic , Dermatology , Education , Japan , Phobic Disorders , Prevalence , Retinal Detachment , Skin Diseases , Skin Diseases, Eczematous , Steroids , TacrolimusABSTRACT
Atopic dermatitis (AD) is a chronic eczematous skin disease attended by pruritus, erythema, edema, excoriation, and dryness. This study was to evaluate the effects of Korean red ginseng (RG) on AD in NC/Nga mice treated with 1-chloro-2,4,6-trinitrobenzene (picryl chloride; PC). Experimental groups were divided into 4 groups; normal control (NC), PC control, and PC-RG (50 and 100 mg/kg). RG was orally administered every day repeatedly during 6 weeks. The skin lesions in severity score, scratching behavior, serum immunoglobulin E (IgE), interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) levels, and histological appearance were examined. AD-like lesions were developed on the NC/Nga mice by topical PC applications. Oral administration of RG (50 and 100 mg/kg) significantly suppressed the development of AD, as analyzed by a modified SCORAD score. The scratching behavior decreased after RG administration. The levels of serum IgE, IL-4 and IFN-gamma were increased by PC stimulation, but treatment with RG (100 mg/kg) suppressed the increment of the serum IgE, IL-4 and IFN-gamma levels. Histologically, RG inhibited dermatitis lesions such as hypertrophy, hyperkeratosis, and infiltration of inflammatory cells into epidermis and dermis. These results suggest that the administration of RG may be effective in alleviating the AD induced by PC.
Subject(s)
Animals , Mice , Administration, Oral , Dermatitis , Dermatitis, Atopic , Dermis , Edema , Epidermis , Erythema , Hypertrophy , Immunoglobulin E , Immunoglobulins , Interferon-gamma , Interleukin-4 , Panax , Picryl Chloride , Pruritus , Skin , Skin Diseases, EczematousABSTRACT
Atopic dermatitis (AD) is a chronic eczematous skin disease attended by pruritus, erythema, edema, excoriation, and dryness. This study was to evaluate the effects of Korean red ginseng (RG) on AD in NC/Nga mice treated with 1-chloro-2,4,6-trinitrobenzene (picryl chloride; PC). Experimental groups were divided into 4 groups; normal control (NC), PC control, and PC-RG (50 and 100 mg/kg). RG was orally administered every day repeatedly during 6 weeks. The skin lesions in severity score, scratching behavior, serum immunoglobulin E (IgE), interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) levels, and histological appearance were examined. AD-like lesions were developed on the NC/Nga mice by topical PC applications. Oral administration of RG (50 and 100 mg/kg) significantly suppressed the development of AD, as analyzed by a modified SCORAD score. The scratching behavior decreased after RG administration. The levels of serum IgE, IL-4 and IFN-gamma were increased by PC stimulation, but treatment with RG (100 mg/kg) suppressed the increment of the serum IgE, IL-4 and IFN-gamma levels. Histologically, RG inhibited dermatitis lesions such as hypertrophy, hyperkeratosis, and infiltration of inflammatory cells into epidermis and dermis. These results suggest that the administration of RG may be effective in alleviating the AD induced by PC.
Subject(s)
Animals , Mice , Administration, Oral , Dermatitis , Dermatitis, Atopic , Dermis , Edema , Epidermis , Erythema , Hypertrophy , Immunoglobulin E , Immunoglobulins , Interferon-gamma , Interleukin-4 , Panax , Picryl Chloride , Pruritus , Skin , Skin Diseases, EczematousSubject(s)
Humans , Male , Female , Infant , Child, Preschool , Dermatitis, Atopic , Skin Diseases, Eczematous , Medical IllustrationSubject(s)
Humans , Female , Child , Skin Diseases, Eczematous , Skin Neoplasms/diagnosis , Glomus Tumor/diagnosisABSTRACT
El presente estudio descriptivo de corte transversal es osbre el comportamiento clínico epidemiológico de la dermatitis atópica diagnosticada en el Centro Nacional de Dermatología Dr. Francisco José Gómez Urcuyo en el período comprendido de enero a junio del 2005 con un universo de 203 pacientes que asistieron a la consulta externa. El grupo etáreo más afectado fue el de 0-10 años, con un 64 porciento, con mayor predominio del sexo femenino, en la procedencia predomino el área urbana capital. En el 50 porciento de los pacientes se encontró que tenia antecedentes familares de asma y alergia. En el 38 porciento la edad de presentación de la enfermedad corresponde a la escala de 0-10 años. La topografía más frecuente fue los pliegues de flexiópn con 63.8 porciento y la morfología que prevaleció son las placas eccematosas. En el 95.5 porciento el diagnóstico fue por clínica. El manejo terapeútico utilzado fue corticoides tópicos, antihistaminico y humectante. Se recomienda la elaboración de un protocolo sobre el manejo de la dermatitis atopica y mejorar los datos en los expedientes clínicos, con énfasis en edad de presentación historia familiar y personal de enfermedad atópica así como morfología y topografía característica de las lesiones...
Subject(s)
Adrenal Cortex Hormones/therapeutic use , Dermatitis, Atopic/diagnosis , Dermatitis, Atopic/epidemiology , Skin Diseases, Eczematous , Clinical Diagnosis , Skin DiseasesABSTRACT
Con el objeto de evaluar la importancia que tiene el hallazgo de Demodex sp. en dermatología humana, se realizó el presente estudio de casos y controles, completando con análisis químico del parásito. Los casos presentaban rosácea o eccematide seborreica, mientras que los controles, piel normal. Las muestras fueron extraídas del rostro mediante aplicación de cintas adhesivas transparentes sobre la piel, las que luego se adhirieron a portaobjetos para buscar el artrópodo por microscopía. El hallazgo de un solo parásito fue suficiente como criterio de positividad. Además se realizó análisis espectrofotométrico de los parásitos, por fluorescencia de rayos X. El 36,6 por ciento de los casos presentó Demodex sp. asociado con dermatitis perioral, rosácea, eccematide seborreica y en conducto nasal asociado a Staphylococcus aureus. Solamente en el 3,3 por ciento de los controles se demostró la presencia del parásito. Odds Ratio: 16,79; X²:8,44; p: 0,0036, límite de confianza 95 por ciento. El análisis espectrométrico por fluorescencia de rayos X, demostró presencia de: calcio, titanio, hierro, azufre, fósforo, cobre, níquel, zinc, potasio, cloro, magnesio, aluminio y silicio en los artrópodos, correspondiendo al cobre y al hierro los picos de mayor intensidad. Luego del tratamiento para Demodex sp. se produjo remisión de los cuadros. Se concluye que existe asociación estadísticamente significativa entre las dermatopatías mencionadas y Demodex sp. El cobre y el hierro de los parásitos podrían, eventualmente, contribuir a agravar los cuadros por reacciones alérgicas
Subject(s)
Humans , Male , Adult , Female , Middle Aged , Mites/pathogenicity , Mite Infestations/etiology , Opportunistic Infections , Mites , Dermatitis, Perioral , Skin Diseases, Eczematous/complications , Skin Diseases, Eczematous/parasitology , Skin Diseases, Parasitic/etiology , Eczema , Stress, Psychological/complications , Mite Infestations/drug therapy , Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications , Permethrin , Pyrethrins , Rosacea , Skin , Virus DiseasesABSTRACT
This study examined the expression of transforming growth factor-beta [TGF-beta] in psoriatic as well as normal skin to elucidate its potential involvement in the pathogenesis of psoriasis and to find out the relation between disease severity and its local expression in the skin. When compared with normal skin, TGF-beta expression was absent or diminished in the epidermis of psoriatic lesions which was more evident in the lower epidermis. Both normal and psoriatic specimens showed minimally detectable TGF-beta in the dermis. A statistically significant correlation was found between TGF-beta expression in the epidermis and disease severity [PASI score]. The result suggested that the lack or diminished TGF-beta-mediated growth inhibition may play an important role in the pathogenesis of psoriasis
Subject(s)
Humans , Male , Female , Psoriasis/immunology , Transforming Growth Factor alpha/immunology , Immunohistochemistry , Skin Diseases, Papulosquamous , Skin Diseases, EczematousABSTRACT
In a prospective study to find out the incidence of various dermatoses in Dammam Central Hospital, Eastern Province, Kingdom of Saudi Arabia a total of 4223 new patients were seen in the years 1992 and 1993 and the commonest diseases found were acne 9%, warts 8.21%, scabies 7.2%, atopic dermatitis 6.8%, urticaria 5%, pityriasis versicolor 4.5%, contact dermatitis 4.3%, pyodermas 3.9%, psoriasis 3.91%, chronic eczema 3.9%, seborrhoeic dermatitis 3.5%, vitiligo 2.3%
Subject(s)
Humans , Male , Female , Skin Diseases, Bacterial/epidemiology , Skin Diseases, Eczematous/epidemiology , Skin Diseases, Infectious/epidemiology , Skin Neoplasms/epidemiologySubject(s)
Humans , Male , Female , Aged , Dermatitis , Herpes Zoster , Skin Diseases, Infectious , Skin Diseases, Eczematous , Skin Diseases, Viral , Skin Diseases, VesiculobullousABSTRACT
Objetivo: Se trata de una revisión para analizar cuáles son los padecimientos dermatológicos más frecuentes que afectan a la población perinatal(mujeres embarazadas, no embarazadas, climatéricas y neonatos) dentro del Instituto Nacional de Perinatología. Material y métodos: Se analizan datos desde mayo de 1991, hasta diciembre de 1993. Para este estudio se tomo como referencia la clasificación de padecimientos dermatológicos basada en la presencia de lesiones primarias y secundarias. Resultados: Se observó que en la población adulta los padecimientos eczematosos y los trastornos de la pigmentación son los más frecuentes. La población pediátrica mostró que los cambios transitorios de la piel neonatal(acné, miliaria, ictericia, hipertricosis, bulas por succión) son la causa más frecuente, seguidos por la xerosis. En este trabajo se puntualizan además conceptos sobre aquellas dermatosis con mayor riesgo perinatal