ABSTRACT
Resumen Los nuevos productos de tabaco, entre los que se incluyen los cigarros electrónicos (denominados "E Cigs", "e-hookahs", "mods", "vape-pens"), los sistemas electrónicos de administración de nicotina (SEAN), los sistemas similares sin nicotina (SSSN) y los sistemas alternativos de consumo de nicotina (SACN), incursionan en el mercado global con un discurso de reducción del daño y minimización del riesgo. Este manuscrito resume la evidencia científica y una propuesta regulatoria sobre esta innovación tecnológica, con el fin de orientar la toma de decisiones de legisladores, instituciones gubernamentales y la sociedad civil organizada. La evidencia científica concluye que no existe un producto de tabaco seguro para la salud; la naturaleza adictiva de la nicotina y los daños a la salud causados en niños, adolescentes y mujeres embarazadas constituyen el argumento fundamental. Estos nuevos productos promueven la transición al consumo de cigarros combustibles y no han demostrado eficacia para la cesación tabáquica; por el contrario, promueven el uso dual. Toda regulación debe formularse sin la intervención de los fabricantes o instituciones con conflicto de interés y en el marco de la implementación completa e integral del Convenio Marco de la Organización Mundial de la Salud para el Control del Tabaco.
Abstract: The new tobacco products that include electronic cigarettes (called "E Cig", "e-hookahs", "mods", "vape-pens"), electronic nicotine delivery systems (SEAN, Spanish acronym), similar systems without nicotine (SSSN, Spanish acronym) and alternative nicotine consumption systems (SACN, Spanish acronym), are positioned in the global market with a discourse of harm reduction and risk minimization. This manuscript summarizes the scientific evidence and presents a regulatory proposal for this technological innovation, oriented to guide the decision making of legislators, government institutions and organized civil society. The scientific evidence concludes that there is no safe tobacco product for health. The addictive nature of nicotine and the health damages for children, adolescents and pregnant women is the fundamental argument. These new products promote the transition to conventional cigarettes and have not shown efficacy for smoking cessation, on the contrary, they promote dual use. High-level regulation must be formulated without the intervention of the manufacturers or institutions with a conflict of interest in the context of the complete and integral World Health Organization Framework Convention on Tobacco Control implementation.
Subject(s)
Humans , Public Health , Tobacco Industry , Tobacco Products , Smoking Prevention , Guidelines as Topic , Smoking Devices , MexicoABSTRACT
@#<p style="text-align: justify;"><strong>BACKGROUND:</strong> New findings on the detrimental health effects of electronic nicotine delivery system (ENDS)/ electronic non-nicotine delivery system (ENNDS) confounds the "harm reduction" perspective of using it as an alternative to conventional cigarettes. In the Philippines, the pressing debate on its safety and efficacy had initiated actions from policy makers on legislative issues such as draft DOH Administrative Order, House Bill 4325 and House Bill 532.</p><p style="text-align: justify;"><strong>OBJECTIVE:</strong> The study aimed to craft an evidence-based policy position on the regulation of ENDS/ENNDS.</p><p style="text-align: justify;"><b>METHODS:</b> Review of literature was conducted, and the proposed scope and measures on electronic cigarette regulation were compared with WHO Framework Convention on Tobacco Control (WHO-FCTC) and existing policies of US FDA regulations on ENDS. Further, UP Manila convened experts of various related fields for evidence-based review and discussion of policy issues to arrive at a consensus policy statement and recommendations. Results. Findings showed that ENDS/ENNDS still need further research to have conclusive results on long term safety and efficacy as smoking cessation methods.</p><p style="text-align: justify;"><strong>CONCLUSION: </strong>Regulations for tobacco control should be clear and supported with strict guidelines in manufacturing, distribution, advertisement, selling, and usage restrictions in public. With the current review, it is recommended that ENDS/ENNDS regulation be under the mandate of the FDA in alignment to WHO-FCTC and to engage different stakeholders from policy makers, implementers, and other involved organizations.</p>
Subject(s)
Humans , Jurisprudence , Smoking DevicesABSTRACT
O objetivo deste trabalho foi verificar as alterações morfológicas nas glândulas parótidas de ratos expostos à fumaça de cigarro por meio da análise histomorfométrica dos ácinos serosos. Foram utilizados 14 ratos Wistar, machos, divididos em dois grupos. Os animais do grupo experimental foram expostos à queima de 4 cigarros por cerca de 30 minutos, duas vezes ao dia, seis dias por semana durante 60 dias consecutivos. Os animais do grupo controle não foram expostos à fumaça de cigarro. A análise estatística dos dados demonstrou que a área dos ácinos serosos dos animais do grupo controle foi significativamente superior.
The aim of this study was to determine the morphological changes in the parotid glands of rats exposed to cigarette smoke by histomorphometric analysis of serous acini. 14 male Wistar rats were divided into two groups were used. The animals of the experimental group were exposed to burning cigarettes 04 for about 30 minutes twice a day, six days a week over a period of 60 consecutive days. The control group were not exposed to cigarette smoke. Statistical analysis of the data showed that the area of the serous acini of the control group was significantly higher.