ABSTRACT
La rigidez cadavérica (rigor mortis) es un proceso no muy bien comprendido por la mayoría de los médicos. El conocimiento de la intimidad del proceso de la rigidez cadavérica es de vital importancia ya que es una de las variables que junto con las livideces (livor mortis) y la temperatura (algor mortis) del cadáver ayudan a determinar el cronotanatodiagnóstico, tanatocronodiagnóstico o intervalo postmortal del período inmediato de la muerte. Para entender el mecanismo de la rigidez y el espasmo cadavérico es preciso hacer un repaso de la contracción muscular fisiológica en el vivo. Hay que tener presente que el tipo de fibra muscular predominante modificará las características de la contracción muscular fisiológica en el vivo, y también la rigidez y el espasmo cadavérico. (AU)
The cadaveric rigidity (rigor mortis) is a process which is not very well understood by the majority of the doctors. The knowledge of the intimacy of the cadaveric stiffness process is of vital importance since it is one of the variables that, as well as the postmortem lividity (livor mortis) and the body temperature post mortem (algor mortis) help determine the chronotanatodiagnostic, tanatochronodiagnostic or postmortal interval of the immediate period of death. In order to understand the mechanism of stiffness and cadaveric spasm, it is necessary to review the physiological muscle contraction in vivo. We should keep in mind that the predominant type of muscle fiber will modify the characteristics of physiological muscle contraction in vivo, as well as stiffness and cadaveric spasm. (AU)
Subject(s)
Humans , Rigor Mortis/physiopathology , Spasm/physiopathology , Muscle Fibers, Skeletal/classification , Muscle Fibers, Skeletal/physiology , Time Factors , Muscle Contraction/physiology , Muscle Relaxation/physiologyABSTRACT
Tonic spasms have been most commonly associated with multiple sclerosis. To date, few reports of series of patients with neuromyelitis optica and tonic spasms have been published. Methods: We analyzed the characteristics and frequency of tonic spasms in 19 subjects with neuromyelitis optica. Data was collected using a semi-structured questionnaire for tonic spasms, by both retrospectively reviewing medical records and performing clinical assessment. Results: All patients except one developed this symptom. The main triggering factors were sudden movements and emotional factors. Spasms were commonly associated to sensory disturbances and worsened during the acute phases of the disease. Carbamazepine was most commonly used to treat the symptom and patients showed good response to the drug. Conclusions: Tonic spasms are a common clinical manifestation in patients with neuromyelitis optica. .
Espasmos tônicos têm sido mais frequentemente associados com esclerose múltipla. Foram publicados até agora poucos relatos de série de pacientes com neuromielite óptica e espasmos tônicos. Métodos: Foram analisadas as características e a frequência de espasmos tônicos em 19 indivíduos com neuromielite óptica. Os dados foram coletados por meio de um questionário semiestruturado para espasmos tônicos, mediante a avaliação retrospectiva dos prontuários e a análise dos dados clínicos Resultados: Todos os pacientes com neuromielite óptica exceto um apresentaram espasmos tônicos. Os principais fatores desencadeantes foram movimentos bruscos e fatores emocionais. Espasmos foram frequentemente associados a perturbações sensoriais e se agravaram durante a fase aguda da doença. A carbamazepina foi utilizada frequentemente para tratar os sintomas, com boa resposta. Conclusões: Os espasmos tônicos são manifestações clínicas frequentes em pacientes com neuromielite óptica. .
Subject(s)
Adolescent , Child , Child, Preschool , Female , Humans , Neuromyelitis Optica/complications , Spasm/etiology , Anticonvulsants/therapeutic use , Carbamazepine/therapeutic use , Neuromyelitis Optica/drug therapy , Neuromyelitis Optica/physiopathology , Risk Factors , Surveys and Questionnaires , Spasm/drug therapy , Spasm/physiopathologyABSTRACT
Accommodative spasm is a rare condition occurring in children, adolescents, and young adults. A familial tendency for this binocular vision disorder has not been reported. I describe accommodative spasm occurring in a brother and sister. Both children presented on the same day with complaints of headaches and blurred vision. Treatment included cycloplegia drops and bifocals. Siblings of patients having accommodative spasm should receive a detailed eye exam with emphasis on recognition of accommodative spasm.
Subject(s)
Accommodation, Ocular/physiology , Adolescent , Child , Female , Headache/etiology , Humans , Male , Retinoscopy , Siblings , Spasm/genetics , Spasm/physiopathology , Vision Disorders/genetics , Vision Disorders/physiopathologyABSTRACT
The significance of intraoperative electrophysiologic monitoring during microvascular decompression was evaluated prospectively in 261 patients with the hemifacial spasm from 1985 to 1995. The patients were divided into a monitored group and a non-monitored group. Identification of the offending vessels was facilitated by the monitoring during the surgical procedure and the complication rate of the monitored group was significantly lower than that of the non-monitored group (p< 0.05). In addition, the abnormal muscle response continued to improve during the follow-up period, thus the electrophysiological status of the hemifacial spasm after the microvascular decompression improved significantly with time (p< 0.05). In conclusion, intraoperative monitoring is useful for identifying the exact offender among multiple vessels, and lowering the complication rate of the microvascular decompression for the hemifacial spasm.
Subject(s)
Adult , Female , Humans , Male , Decompression, Surgical , Facial Muscles , Follow-Up Studies , Middle Aged , Monitoring, Intraoperative , Spasm/physiopathologyABSTRACT
Twenty patients with primary hemifacial spasm and ten patients with Parkinson's disease were studied by means of paired stimuli blink reflex. The second stimuli were delivered at a varying time interval between 50-900 ms. The R2 response's absolute refractory periods were compared between patients and twenty one age-matched normal controls as well as between hemifacial spasm and Parkinson's disease. In normal subjects, the mean absolute refractory period was found to be 271.42 +/- 64.36 ms, in hemifacial spasm 160.00 +/- 50.62 ms and in Parkinson's disease 157.14 +/- 53.45 ms. The absolute refractory periods obtained from patients were significantly shorter than in normal controls (p < 0.05). However the values between patients with hemifacial spasm and Parkinson's disease were not (p > 0.05). This result strongly supports bilateral facial motoneurons hyperexcitability as the underlying mechanism of hemifacial spasm.
Subject(s)
Adult , Case-Control Studies , Facial Muscles/physiopathology , Female , Humans , Male , Middle Aged , Motor Neurons/physiology , Refractory Period, Electrophysiological , Spasm/physiopathologyABSTRACT
Num período de 10 anos, 53 pacientes com espasmo hemifacial foram submetidos a 54 procedimentos de descompressäo microvascular da raiz do facial, na fossa posterior. A técnica empregada foi a mesma desenvolvida por Jannetta e o resultado cirúrgico inicial foi considerado excelente em 91% dos casos. O follow-up variou de 60 dias a 7 anos, com 40 pacientes acompanhados por mais de 2 anos e 16, por mais de 5 anos. Apenas um apciente apresentou recidiva dos espasmos. Näo houve óbito e as complicaçöes näo foram importantes, sendo, em sua maioria, transitórias e relacionadas à VII e VII raízes. Em 4 pacientes näo encontramos compressäo da raiz. Concluimos que, quaisquer sejam as causas do espasmo hemifacial ou mecanismos de açäo da cirurgia, os resultados da descompressäo microvascular säo excelentes, a curto e longo prazo, e superiores aos obtidos pelas demais formas de tratamento clínico ou cirúrgico