Sperm motility and viability in west African dwarf rams treated with Euphorbia hirta / Motilidad y viabilidad espermática en carneros enanos del oeste africano tratados con Euphorbia hirta

Four adult sexually matured and clinically healthy West African Dwarf (WAD) rams aged between 24 and 30 months were used for the study. The rams were first used as control and later as experimental animals upon being orally dosed with Euphorbia hirta extract at 400mg/kg body weight for 14 days. Semen samples were collected from the rams a day after the administration of the plant extra and seven days after. The objective of the study was to investigate the effect of Euphorbia hirta on the semen picture of WAD rams. There were significantly differences (P <0.05) in the semen picture as reflected in a reduction of sperm motility from 80% to 47.5% and live-dead ratio from 90.75% to 32.5% in the control and post-experimental stages of the study respectively. This indicates that the fertilization capacity and livability of spermatozoa were negatively affected. There were no significant differences in the values of body parameters measured across the stages of the study. The plant is therefore not recommended for medicinal purpose in male animals.

Cuatro carneros enanos adultos de África Occidental sexualmente maduros y clínicamente sanos, con edades comprendidas entre los 24 y 30 meses, fueron utilizados para este estudio. Los carneros fueron utilizados como control y, más tarde, como animales de experimentación al ser medicados por vía oral con extracto de Euphorbia hirta en 400mg/kg peso corporal durante 14 días. Se recogieron muestras de semen de los carneros un día después de la administración de la planta y siete días después. El objetivo del estudio fue investigar el efecto de Euphorbia hirta en las imágenes de esperma de carneros enanos África Occidental. Hubo diferencias significativas (P <0,05) en la imagen del semen como reflejo de una reducción de la motilidad espermática del 80% al 47,5% y un ratio de vivos-muertos de 90,75% a 32,5% en la etapa control y después de las fases experimentales del estudio, respectivamente. Esto indica que la capacidad de fertilización y calidad de vida de los espermatozoides fueron afectados negativamente. No hubo diferencias significativas en los valores de los parámetros corporales medidos a través de las etapas del estudio. La planta por tanto no es recomendable para fines medicinales en los animales machos.

Sperm antibodies and unexplained infertility in females

Immunological factors as a possible cause for unexplained infertility was investigated in 50 infertile patients and a Similar number of women taken as a control The investigated [positive sperm immobilizing antibody test [SIT] was Significantly higher among the infertile group than the control. This significant Association was not found with the sperm agglutinating antibody test [SAT]

Effect of Homologous Human Semen Mixtures on Viability of Sperm / 대한비뇨기과학회지

The causes of male infertility have been well delineated in numerous textbooks and articles. These are divided into six major categories such as failure of spermatogenesis, failure of sperm maturation, failure of sperm transportation, failure of semen composition, failure of hormonal system and failure of ejaculation. Besides these, the motile activity of sperm has been regarded as an important factor for the impregnation This clinical study has been undertaken to examine the effects of hemologous human semen mixtures upon the motile time of the spermatozoa, and the result are presented as follows; Group 1, Mixture of Normospermia and Normospermia: 10 mixtures Normospermia-A: 471. 9 minutes of aver age sperm motile time Normospermia-B: 369. 4 minutes of average sperm motile time Normo-A+Normo-B mixture: 452. 5 minutes of average sperm motile time Group 2, Mixture of Normospermia and Oligospermia: 10 mixtures Normospermia: 445.3 minutes of average sperm motile time Oligospermia: 376.2 minutes of average sperm motile time Normo+Oligo mixture: 456. 1 minutes of average sperm motile time Group 3, Mixture of Normospermia and Azoospermia; 8 mixtures Normospermia: 433. 3 minutes of average sperm motile time Azoospermia: Normo.+Azoo. mixture: 455. 1 minutes of average sperm motile time Group 4, Mixture of Oligospermia and Azoospermia; 6 mixtures Oligospermia: 343. 6 minutes of average sperm motile time Azoospermia: Oligo.+Azoo. mixture: 348. 1 minutes of average serum motile time In In conclusion, 1. no mutual spermicidal effect but tendency toward enhancement of sperm motile time 2. no sperm agglutinating phenomenon nor sperm immobilizing effect were noted in various semen mixtures 3. posibilities of clinical application such as AID arc considerable and 4. further studies are needed in conjunction with the serum autoimmune mechanism.