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Indian J Exp Biol ; 1992 Dec; 30(12): 1181-3
Article in English | IMSEAR | ID: sea-63156

ABSTRACT

Oral administration of spirobishexahydropyrimidine showed an increase in the activity of serum transaminases, lactate dehydrogenase and alkaline phosphatase. Biological half life and other pharmacokinetic parameters showed rapid absorption and slow elimination of the drug.


Subject(s)
Alanine Transaminase/blood , Alkaline Phosphatase/blood , Animals , Aspartate Aminotransferases/blood , Kinetics , L-Lactate Dehydrogenase/blood , Pyrimidines/pharmacokinetics , Rabbits , Spiro Compounds/pharmacokinetics
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