ABSTRACT
Background: Surgical wound infections, are common post-operative complications, that cause significant postoperative morbidity and mortality. Aim of the study: To isolate, identify and study the antimicrobial sensitivity of E. coli isolates from surgical wounds. Methodology: A total of 1088 pus samples were received over a period of one year from post-operative wounds. 313 isolates of E. coli were recovered and identified and antimicrobial sensitivity testing (AST) including extended spectrum beta lactamases (ESBL) detection was performed according to Clinical Laboratory Standard Institute (CLSI) guidelines. Results: E. coli accounted for 37.5% . ESBL production was detected in 22.0% of E. coli isolates. Conclusion: Our study shows that there is increased isolation rate of E. coli from post-operative wound infections. Hospital disinfection and treatment protocols should be practiced thoroughly and regularly monitored to control the incidence of wound infections.