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1.
Rev. cuba. med. mil ; 31(4)oct.-dic. 2002.
Article in Spanish | LILACS | ID: lil-354379

ABSTRACT

Se hizo una revisión bibliográfica de la profilaxis antibiótica en Cirugía y Ortopedia, sus bases fisiológicas, los principios en que se basan sus indicaciones, ventajas, errores más comunes, modo de utilización y selección del fármaco a utilizar en el momento actual. Se hacen recomendaciones para su utilización correcta de acuerdo con los gérmenes más frecuentes con el objetivo de minimizar los efectos adversos y costos de tratamiento. Se evidencia el hecho de que disminuir o evitar la infección de las heridas quirúrgicas, le confieren al método singular importancia en la cirugía moderna, por lo que es imprescindible su empleo sistemático


Subject(s)
Humans , Surgical Wound Infection/methods , Orthopedic Procedures , Antibiotic Prophylaxis/methods
2.
PJMR-Pakistan Journal of Medical Research. 1996; 35 (2): 70-73
in English | IMEMR | ID: emr-43032

ABSTRACT

A total of 280 patients undergoing appendectomy for acute appendicitis were prospectively studied in two groups, group I, comprising 134 patients, group II included 146 patients who received intraoperative topical ampicillin irrigation of the wound. All patients additionally received preoperative systemic ampicillin and flagyl. Both groups were comparable with regard to age, sex, duration of symptoms, and severity of acute appendicitis. Wound infection occurred in 19% in group 1, compared to only 5% in group II [P <0.05]. The reduction in wound infection was significant [P< 0.05] in histologically proven appendicitis. We conclude that the addition of intraoperative topical ampicillin to systemic ampicillin and flagyl augments prophylaxis against wound infection in acute appendicitis


Subject(s)
Humans , Ampicillin , Wounds and Injuries/prevention & control , Surgical Wound Infection/methods
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