ABSTRACT
Abstract: Ductal eccrine carcinoma (DEC) is a rare sweat gland carcinoma with ductular differentiation. Clinically, it is characterized by a slowly growing, hardened plaque or nodule predominantly located on the head and neck. Histologically, DEC shares similar features to invasive breast carcinoma, thus causing great diagnostic challenges. We report a 69-year-old woman who presented with a hardened plaque on the axilla. A skin biopsy was performed and metastatic invasive breast carcinoma could not be ruled out. Complete excision and further workup were subsequently conducted, leading to the diagnosis of estrogen receptor positive DEC with associated axillary lymph node metastases. The patient received adjuvant radiotherapy to the left axilla and was started on oral letrozole. She is disease-free 14 months after initial diagnosis.
Subject(s)
Humans , Female , Aged , Sweat Gland Neoplasms/pathology , Carcinoma, Skin Appendage/pathology , Carcinoma, Ductal, Breast/pathology , Axilla , Sweat Gland Neoplasms/diagnosis , Sweat Gland Neoplasms/therapy , Carcinoma, Skin Appendage/diagnosis , Carcinoma, Skin Appendage/therapy , Carcinoma, Ductal, Breast/diagnosis , Diagnosis, Differential , Lymph Nodes/pathology , Lymphatic MetastasisABSTRACT
Abstract Squamoid eccrine ductal carcinoma is an eccrine carcinoma subtype, and only twelve cases have been reported until now. It is a rare tumor and its histopathological diagnosis is difficult. Almost half of patients are misdiagnosed as squamous cell carcinoma by the incisional biopsy. We report the thirteenth case of squamoid eccrine ductal carcinoma. Female patient, 72 years old, in the last 6 months presenting erythematous, keratotic and ulcerated papules on the nose. The incisional biopsy diagnosed squamoid eccrine ductal carcinoma. After excision, histopathology revealed positive margins. A wideningmargins surgery and grafting were performed, which again resulted in positive margins. The patient was then referred for radiotherapy. After 25 sessions, the injury reappeared. After another surgery, although the intraoperative biopsy showed free surgical margins, the product of resection revealed persistent lesion. Distinction between squamoid eccrine ductal carcinoma and squamous cell carcinoma is important because of the more aggressive nature of the first, which requires wider margins surgery to avoid recurrence.
Subject(s)
Humans , Aged , Sweat Gland Neoplasms/pathology , Carcinoma, Ductal/pathology , Eccrine Glands/pathology , Sweat Gland Neoplasms/therapy , Biopsy , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/therapy , Nose/pathology , Carcinoma, Ductal/therapy , Neoplasm Recurrence, LocalABSTRACT
El Hamartoma Angiomatoso Ecrino /HAE) es una malformación combinada: vascular y ecrina, benigna, poco frecuente, que se presenta al nacimiento o en la infancia, ubicada generalmente en las extremidades. Es de crecimiento lento, proporcional al crecimiento del niño, generalmente único. Se presenta habitualmente como una placa o nódulo de color rojo, violáceo o color piel. Puede presentar dolor, hipertricosis e hiperhidrosis local, características que lo diferencian de otras malformaciones vasculares. A la histología se observa un aumento de glándulas ecrinas, maduras, en la dermis, acompañadas de acúmulos de vasos sanguíneos (capilares) dilatados. El tratamiento de elección del HAE es la resección quirúrgica. Describimos dos casos de HAE diagnosticados en un periodo de tres años en el Servicio de Dermatología del Hospital Barros Luco-Trudeau.
Subject(s)
Female , Adult , Humans , Hamartoma/pathology , Sweat Gland Neoplasms/pathology , Skin/pathology , Diagnosis, Differential , Eccrine Glands/pathology , Hamartoma/congenital , Hamartoma/diagnosis , Hamartoma/therapy , Sweat Gland Neoplasms/congenital , Sweat Gland Neoplasms/diagnosis , Sweat Gland Neoplasms/therapyABSTRACT
Se reportan 2 enfermos con diagnostico de carcinoma de la mama operados en el Hospital Provincial Clinicoquirurgico Docente "Dr. Gustavo Aldereguia Lima" de Cienfuegos, que constituyen los 2 primeros casos conocidos en nuestra literatura. En ambos casos no se observaron recidivas despues de los 2 y 7 anos repectivemente de intervenidos y de completar el tratamiento con coblatoterapia posoperatoria
Subject(s)
Humans , Male , Female , Aged , Breast Neoplasms/pathology , Breast Neoplasms/surgery , Breast Neoplasms/therapy , Carcinoma/pathology , Carcinoma/surgery , Carcinoma/therapy , Cobalt/therapeutic use , Sweat Gland Neoplasms/pathology , Sweat Gland Neoplasms/surgery , Sweat Gland Neoplasms/therapyABSTRACT
Se presenta un caso de poroma ecrino maligno, tumor de rara presentación, en una mujer de raza blanca de 68 años de edad. La lesión, localizada en dorso de pie izquierdo, estaba presente desde hacía tres años y era asintomática. Se realiza una pequeña revisión del tema