ABSTRACT
Angiosarcoma accounts for 1% of all soft tissue sarcoma. Common sites of occurrence include the skin, breast, soft tissue, and liver. It metastasizes to the lungs, bone, and spleen. The cause of hepatic angiosarcoma in the 60% of cases is unknown, although specific risk factors such as vinyl chloride, arsenic, thorotrast and external-beam irradiation have been identified. Since 1986, about eight cases of hepatic angiosarcoma have been reported in Korea, but it had not been reported in which the hepatic angiosarcoma invaded to the stomach, yet. So we report a case of histopathologically confirmed primary hepatic angiosarcoma with gastric involvement. In this case, a sixtythree-year-old female was presented with indigestion and epigastric soreness for 1 year. Endoscopic examination of the stomach revealed a submucosal tumor-like protruding mass from the antrum to angle. The mucosal surface showed severe hyperemia and shallow ulcerative change was seen. Endoscopic biopsy and percutaneous liver biopsy confirmed the diagnosis of hepatic angiosarcoma invading the gastric wall.
Subject(s)
Female , Humans , Arsenic , Biopsy , Breast , Diagnosis , Dyspepsia , Hemangiosarcoma , Hyperemia , Korea , Liver , Lung , Risk Factors , Sarcoma , Skin , Spleen , Stomach , Thorium Dioxide , Ulcer , Vinyl ChlorideABSTRACT
In spite of its rarity, hepatic angiosarcoma is of special interest because specific risk factors such as thorium dioxide, arsenic, and vinyl chloride have been identified. We report a case of histopathologically confirmed primary angiosarcoma of the liver which was found in a farmer. In this case, 73-ear old man was presented with right upper abdominal pain and fatigue. Abdominal ultrasonography, CT scan and MRI revealed a mass occupying broad area of the right lobe of the liver. Histopathologic diagnosis of angiosarcoma was made by percutaneous needle biopsy.
Subject(s)
Abdominal Pain , Arsenic , Biopsy, Needle , Diagnosis , Fatigue , Hemangiosarcoma , Liver , Magnetic Resonance Imaging , Risk Factors , Thorium Dioxide , Tomography, X-Ray Computed , Ultrasonography , Vinyl ChlorideABSTRACT
As curas de doencas reumaticas e outras enfermidades observadas nos ultimos 40 anos, que a intuicao popular discerniu nas praias de areia monazitica da cidade de Guarapari, foram confirmadas pelos medicos locais e visitantes da grande estancia radioclimatica.Os efeitos da nova medicacao, atribuidos pelo medico brasileiro Silva Mello como resultantes da radioatividade ambiente, foram confirmados pelos fisicos da Pontificia Universidade Catolica do Rio de Janeiro, os padres jesuitas Roser e Cullen, apos investigacoes em rigorosas determinacoes fisicas sobre a radioatividade decorrente do oxido de torio, existente na proporcao de 6,4%. E este o novo medicamento original e inocuo, desconhecido nos anais da Biologia medica, que divulgamos no presente estudo, sugerindo a nossa juventude medica novo tema de investigacoes de alto interesse medico-social