ABSTRACT
Hydatidiform mole (HM) is not uncommon in our country. Its dangerous sequalae is the fatal persistent trophoblastic disease (PTD). The prognostic risk factors for the development of PTD were analyzed in 108 cases of HM treated in Ramathibodi Hospital from 1978 to 1986. Statistical univariate analysis was by calculation of relative risk (RR) and chi-square test. The incidence of PTD was 27.8 per cent. The significant risk factors were the presence of theca-lutein cyst, gestational age of less than 16 weeks, "large for date" uterus, and patients' age of 40 years or more. Their RR were 4.25, 3.11, 3.00 and 2.68 respectively. These findings were comparable with previous reports. The use of prophylactic chemotherapy in patients with these risk factors was suggested.
Subject(s)
Adolescent , Adult , Female , Humans , Hydatidiform Mole/complications , Middle Aged , Pregnancy , Risk Factors , Thailand/epidemiology , Trophoblastic Neoplasms/etiology , Uterine Neoplasms/complicationsABSTRACT
Por ser este un informe preliminar, con un volumen pequeño de casos y un seguimiento muy corto, no estaba dentro de los objetivos analizar resultados en forma definitiva ni dar pautas de manejo, hasta tanto no se determine la investigación. Sin embargo, en este trabajo se recalca la importancia de esta patología en nuestro medio la necesidad de un estudio sistematizado con los métodos actuales tanto de diagnóstico como de seguimiento y tratamiento con miras a obtener mejores resultados