ABSTRACT
Cancer of the uterine cervix has been related to HPV infection, based on clinical and laboratory data. The high recurrence rate in couples undergoing treatment for HPV infection points to a probable viral reservoir, either in subclinical lesions or in male internal genital organs. We have evaluated 31 men, all sexual partners of women with HPV infection. Eleven patients (35.5%) had related lesions: 4 (12.9%) with condyloma acuminatum; 5(16.1%) with lesions revealed by magnified examination after reaction with 5% acetic acid and 2(6.5%) with condyloma and subclinical lesions. A short-term follow-up confirmed a successful treatment with podophyllin
Subject(s)
Humans , Male , Adult , Middle Aged , Papillomaviridae/pathogenicity , Condylomata Acuminata/etiology , Uterine Cervical Neoplasms/complications , Tumor Virus Infections/transmission , Urologic Neoplasms/etiology , Sexual Partners , DNA Probes, HPVABSTRACT
Foram examinados 60 parceiros sexuais, de mulheres diagnosticadas como portadoras de infeccao genital pelo papilomavirus, sob protocolo de investigacao. O objetivo era identificar colposcopicamente, lesoes acetobrancas na genitalia externa masculina, biopsia-las e estuda-las histopatologicamente. Predominava como sinal patognomonico, a coilocitose celular. A biopsia foi positiva em 77,1 por cento e negativa em 22,9 por cento. Os resultados da pesquisa fecham a hipotese de que o parceiro sexual masculino e, de fato, um elemento de risco, agindo como transmissor de infeccao genital pelo papilomavirus humano.