Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters








Language
Year range
1.
Rev. Inst. Med. Trop. Säo Paulo ; 51(5): 295-298, Sept.-Oct. 2009. ilus, tab
Article in English | LILACS | ID: lil-530137

ABSTRACT

We report a case of accidental infection by Trypanosoma cruzi in a 42-year-old female patient who presented an inoculation chagoma. Laboratory confirmation was based on examination of fresh blood, Giemsa-stained blood smear, immunoenzyme test (EIA-IgG), indirect immunofluorescence (IIF-IgM, IgG) and polymerase chain reaction (PCR). Only the PCR gave a positive result, and the EIA test was inconclusive. Two treatments with benznidazole were necessary. PCR was the only technique that continued to give positive results for approximately two months (65 days, or 2.2 months) following the second treatment and negative results from 96 days (3.2 months) to 850 days (28.3 months). We concluded that the presence of an inoculation chagoma and use of PCR were important and decisive for diagnosis and follow-up of the case.


Reportamos caso de infecção acidental pelo Trypanosoma cruzi em paciente do gênero feminino, 42 anos, que apresentou chagoma de inoculação. A confirmação laboratorial foi realizada pelo exame de sangue a fresco, esfregaço corado com Giemsa, imunoenzimaensaio (ELISA-IgG), imunofluorescência indireta (IFI-IgM, IgG) e reação em cadeia da polimerase (PCR). Somente a PCR foi positiva e a ELISA foi inconclusiva. Dois tratamentos com benznidazol foram necessários. PCR foi a única técnica que permaneceu positiva por aproximadamente dois meses (65 dias ou 2,2 meses) após o segundo tratamento e negativa de 96 dias (3,2 meses) a 850 dias (28,3 meses). Concluimos que a presença do chagoma de inoculação e o uso da PCR foram importantes e decisivos para o diagnóstico e o acompanhamento do caso.


Subject(s)
Adult , Animals , Female , Humans , Accidents, Occupational , Chagas Disease/etiology , Chagas Disease/transmission , Laboratory Personnel , Trypanosoma cruzi , Chagas Disease/diagnosis , Chagas Disease/drug therapy , Enzyme-Linked Immunosorbent Assay , Fluorescent Antibody Technique, Indirect , Hand Injuries/parasitology , Nitroimidazoles/therapeutic use , Polymerase Chain Reaction , Trypanocidal Agents/therapeutic use , Trypanosoma cruzi/genetics , Trypanosoma cruzi/immunology , Wounds, Stab/parasitology
SELECTION OF CITATIONS
SEARCH DETAIL