Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 74
Filter
1.
Prensa méd. argent ; 107(7): 353-359, 20210000. fig
Article in Spanish | LILACS, BINACIS | ID: biblio-1358932

ABSTRACT

Se analiza una de las complicaciones de la lipoaspiración abdominal: la perforación intestinal intra-operatoria por la cánula (instrumental). Se describe la relación entre la cánula, la pared abdominal y el intestino delgado: los tres componentes de esta complicación. Se detallaron las características de las cánulas generalmente empleadas y la técnica quirúrgica de la lipoaspiración abdominal, así como el cuadro clínico ocasionado y cómo tratarlo


One of the complications of abdominal liposuction is analyzed: intra-operative intestinal perforation by the cannula (instrumental). The relationship between the cannula, the abdominal wall and the small intestine is described: the three components of this complication. The characteristics of the cannulas generally used and the surgical technique of abdominal liposuction were detailed, as well as the clinical picture caused and how to treat it.


Subject(s)
Humans , Lipectomy/methods , Medical Errors , Abdominal Wall/pathology , Cannula/adverse effects , Intestinal Perforation/prevention & control , Intraoperative Complications/prevention & control
2.
Prensa méd. argent ; 106(9): 520-523, 20200000. fig
Article in Spanish | LILACS, BINACIS | ID: biblio-1362772

ABSTRACT

Introducción: Las úlceras de Marjolin son neoplasias cutáneas que asientan sobre pieles afectadas por úlceras crónicas, quemaduras, cicatrices, estasis venosa o heridas cutáneas. Generalmente se diagnostica por medio de biopsias, siendo los carcinomas escamosos la variedad más frecuente. Existe escasa información sobre su desarrollo en heridas quirúrgicas abdominales previas, y aún menos casos reportados de su aparición sobre un defecto de la pared abdominal. Objetivo: Reporte de un caso de un paciente con antecedente de múltiples cirugías abdominales que desarrolló un carcinoma escamoso sobre cicatriz de laparotomía previa. Pacientes y Métodos: Presentación de un de un paciente masculino de 61 años, con antecedente de laparotomía exploradora, que consultó por una tumoración, de 6 meses de evolución, vegetante sobre eventración de mediana suprainfraumbilical. Se realiza exéresis de lesión en bloque de pared con enterectomia, anastomosis primaria y eventroplastia con malla de reemplazo. Cursa internación prolongada y con mala evolución, falleciendo al 77 día postoperatorio. Conclusión: Los carcinomas de células escamosas que se desarrollan sobre lesiones cutáneas previas presentan una agresividad mayor a aquellos desarrollados espontáneamente, tienen alto porcentaje de recidiva y metástasis asociadas. Se propone abordajes quirúrgicos radicales para su tratamiento, aun asi presentando una morbimortalidad elevada


Background: Marjolin ulcers are skin malignancies that appear on skin affected by chronic ulcers, burns, scars, venous stasis or skin wounds. They are generally diagnosed through a biopsy and the most frequent type is the squamous cell carcinoma. There is little information on its development in existing abdominal surgical wounds, and there are even fewer cases reported in relation to its appearance upon an abdominal wall defect. Objective: To report a case of a patient with a history of multiple abdominal surgeries who developed a squamous cell carcinoma in an existing laparotomy scar in association with an incisional hernia. Patient and Methods: A 61-year-old male patient, with history of an exploratory laparotomy in 1986, presents with a 6-month-old vegetating tumor upon a supra-infraumbilical median eventration. An excision of the lesion that included the abdominal wall and an associated enterectomy, primary anastomosis, and eventroplasty with replacement mesh was performed. During his prolonged hospital stay, he underwent with many medical intercurrences and even an additional surgery was needed. Eventually, the patient dies 77 days after the surgery. Conclusion: Squamous cell carcinomas that develop in existing skin lesions tend to be more aggressive than those that develop spontaneously. They have a high percentage of recurrence and associated metastases. Radical surgical approaches are suggested for its treatment, although it has a high morbidity and mortality rate.


Subject(s)
Humans , Male , Middle Aged , Recurrence , Skin Neoplasms/therapy , Skin Ulcer/surgery , Carcinoma, Squamous Cell/surgery , Carcinoma, Squamous Cell/mortality , Carcinoma, Squamous Cell/therapy , Abdominal Wall/pathology , Neoplasm Metastasis/therapy
3.
Rev. Col. Bras. Cir ; 47: e20202544, 2020. tab, graf
Article in English | LILACS | ID: biblio-1136600

ABSTRACT

ABSTRACT Objective: to study the characteristics of women undergoing abdominal surgery with suspected abdominal wall endometriosis or abdominal wall tumor, and to assess the association with age, race and previous cesarean delivery. Method: retrospective and analytical study carried out from January 2000 to December 2019, at the General Surgery Service of Hospital Universitário Antônio Pedro (HUAP) at Universidade Federal Fluminense (UFF). Medical records of 100 patients with abdominal wall endometriosis and other types of abdominal wall tumors were analyzed. Age, color, previous history of cesarean section or abdominal surgery and histopathological data were verified. The patients were classified as young adults (aged between 18 and 28 years and 11 months) and adults. The SPSS program was used for data analysis, Fisher's test with a significance level of 0.05. Results: abdominal wall endometriosis with histopathological confirmation was found in 22%, the mean age was 52.28 ± 18.66 which was lower when compared to other diagnoses. There was an association between previous cesarean section and abdominal wall endometriosis (p <0.005). Conclusion: the women with a diagnosis of abdominal wall endometriosis had undergone previous cesareans (the majority) and were in an active reproductive age. Although the brown skin women were the most frequent, there was no statistical difference.


RESUMO Objetivo: estudar o perfil das mulheres submetidas a cirurgia abdominal com suspeita de endometriose de parede abdominal ou tumor de parede abdominal e analisar a associação com a faixa etária, cor e cesariana prévia. Métodos: estudo retrospectivo e analítico realizado no período de janeiro de 2000 a dezembro de 2019, no Serviço de Cirurgia Geral do Hospital Universitário Antônio Pedro (HUAP) da Universidade Federal Fluminense (UFF). Analisaram-se prontuários de 100 pacientes com endometriose de parede abdominal e com outros tipos de tumoração de parede abdominal. Idade, cor, histórico prévio de cesariana ou cirurgia abdominal e resultado histopatológico foram avaliados. As pacientes foram classificadas em adultas jovem (idade entre 18 e 28 anos e 11 meses) e adultas. Utilizou-se para a análise dos dados o programa SPSS e, teste de Fisher com nível de significância de 0,05. Resultados: Endometriose de parede abdominal com confirmação histopatológica foi encontrada em 22% dos casos. A média de idade foi 52.28 ±18,66, menor quando comparada a outros diagnósticos. Observou-se associação entre cesariana prévia e endometriose de parede abdominal (p<0,005). Conclusão: as mulheres atendidas pelo Setor de Cirurgia da UFF com diagnóstico de endometriose de parede abdominal, na maioria, realizaram cesariana prévia e estavam em idade ativa, reprodutiva. Apesar da cor parda ter sido mais frequente, não se observou diferença estatística.


Subject(s)
Humans , Female , Pregnancy , Adult , Aged , Young Adult , Postoperative Complications , Cesarean Section/adverse effects , Abdominal Wall/pathology , Endometriosis/diagnosis , Retrospective Studies , Abdominal Wall/surgery , Endometriosis/surgery , Endometriosis/etiology , Hospitals, University , Middle Aged
4.
Rev. Col. Bras. Cir ; 46(6): e20192322, 2019. tab, graf
Article in Portuguese | LILACS | ID: biblio-1057185

ABSTRACT

RESUMO Objetivo: avaliar os efeitos da arginina na cicatrização da parede abdominal de ratos Wistar. Métodos: vinte ratos Wistar foram submetidos à laparotomia e separados em dois grupos (arginina e controle), que receberam tratamento diário por via intraperitoneal com arginina (300mg/kg/dia) e solução tampão fosfato em dose equivalente ao peso, respectivamente, durante cinco dias. No sétimo dia pós-operatório, coletaram-se amostras de sangue e da cicatriz da parede abdominal de ambos os grupos. Avaliaram-se o nível sérico de nitratos e nitritos, a evolução cicatricial pelas dosagens de hidroxiprolina tecidual, formação de tecido de granulação, determinação da porcentagem de colágeno maduro e imaturo, densidade de miofibroblastos e angiogênese. Empregaram-se os testes de ANOVA e t de Student com p=0,05 para as comparações entre os grupos. Resultados: não ocorreram diferenças significantes entre os grupos estudados para dosagens de nitratos e nitritos (p=0,9903), hidroxiprolina tecidual (p=0,1315) e densidade de miofibroblastos (p=0,0511). O grupo arginina apresentou maior densidade microvascular (p=0,0008), maior porcentagem de colágeno tipo I (p=0,0064) e melhora na formação do tecido de granulação, com melhores índices de proliferação angiofibroblástica (p=0,0007) e re-epitelização das bordas (p=0,0074). Conclusão: na avaliação cicatricial da parede abdominal de ratos Wistar sob tratamento com arginina, não houve alteração do nível sérico de nitratos e nitritos, da deposição de colágeno total e da densidade de miofibroblastos. Verificaram-se aumento da maturação de colágeno do tipo I, da densidade microvascular e melhora na formação do tecido de granulação cicatricial pelas melhores re-epitelização de bordas e proliferação angiofibroblástica.


ABSTRACT Objective: to evaluate the effects of arginine on abdominal wall healing in rats. Methods: we submitted 20 Wistar rats to laparotomy and divided them into two groups, arginine and control, which then received, respectively, daily intraperitoneal treatment with arginine (300mg/kg/day) and weight-equivalent phosphate buffered solution, during five days. On the seventh postoperative day, we collected blood and scar wall samples from both groups. We evaluated serum nitrate and nitrite levels, wound evolution by tissue hydroxyproline dosages, granulation tissue formation, percentage of mature and immature collagen, myofibroblast density and angiogenesis. We used the ANOVA and the Student's t tests with p=0.05 for comparisons between groups. Results: there were no significant differences between the groups studied for nitrate and nitrite (p=0.9903), tissue hydroxyproline (p=0.1315) and myofibroblast density (p=0.0511). The arginine group presented higher microvascular density (p=0.0008), higher percentage of type I collagen (p=0.0064) and improved granulation tissue formation, with better angiofibroblastic proliferation rates (p=0.0007) and wound edge reepithelization (p=0.0074). Conclusion: in the abdominal wall healing evaluation of Wistar rats under arginine treatment, there was no change in serum nitrate and nitrite levels, total collagen deposition and myofibroblast density. There was an increase in type I collagen maturation, microvascular density and improvement in scar granulation tissue formation by better edge reepithelization and angiofibroblastic proliferation.


Subject(s)
Animals , Rats , Arginine/pharmacology , Wound Healing/drug effects , Collagen/drug effects , Abdominal Wall/surgery , Collagen/metabolism , Rats, Wistar , Models, Animal , Abdominal Wall/pathology , Myofibroblasts/drug effects , Abdominal Injuries/drug therapy
5.
Acta cir. bras ; 34(6): e201900603, 2019. tab, graf
Article in English | LILACS | ID: biblio-1019263

ABSTRACT

Abstract Purpose To Compare the extent and intensity of adhesions formed between the intra-abdominal organs and the intraperitoneal implants of polypropylene mesh versus polypropylene/polyglecaprone versus polyester/porcine collagen used for correction of abdominal wall defect in rats. Methods After the defect in the abdominal wall, thirty Wistar rats were placed in three groups (ten animals each) for intraperitoneal mesh implant: polypropylene group, polypropylene/polyglecaprone group, and polyester/porcine collagen group. The macroscopic evaluation of the extent and intensity of adhesions was performed 21 days after the implant. Results The polypropylene group had a higher statistically significant impairment due to visceral adhesions (p value = 0.002) and a higher degree of intense adherence in relation to polypropylene/polyglecaprone and polyester/porcine collagen groups (p value<0.001). The polyester/porcine collagen group showed more intense adhesions than the polypropylene/polyglecaprone group (p value=0.035). Conclusions The intraperitoneal implantation of polypropylene meshes to correct defects of the abdominal wall caused the appearance of extensive and firm adhesions to intra-abdominal structures. The use of polypropylene/polyglecaprone or polyester/porcine collagen tissue-separating meshes reduces the number and degree of adhesions formed.


Subject(s)
Animals , Male , Rats , Peritoneal Diseases/etiology , Polyesters/administration & dosage , Polypropylenes/administration & dosage , Surgical Mesh/adverse effects , Tissue Adhesions/etiology , Collagen/administration & dosage , Dioxanes/administration & dosage , Polyesters/adverse effects , Polypropylenes/adverse effects , Materials Testing , Collagen/adverse effects , Rats, Wistar , Abdominal Wall/pathology , Dioxanes/adverse effects
6.
Acta cir. bras ; 33(9): 792-798, Sept. 2018. graf
Article in English | LILACS | ID: biblio-973505

ABSTRACT

Abstract Purpose: To evaluate the fibrosis induced by four different meshes: Marlex®, Parietex Composite®, Vicryl® and Ultrapro®. Methods: Histological cutouts of abdominal wall were analyzed with polarized light 28 days after the meshes implants and colorized by picrosirius to identify the intensity of collagen types I and III, and their maturation index. Results: When the four groups were compared, the total collagen area analyzed was bigger in groups A and D, with no difference between them. The collagen type I density was bigger in group A, with an average of 9.62 ± 1.0, and smaller in group C, with an average of 3.86 ± 0.59. The collagen type III density was similar in groups A, B and C, and bigger in group D. The collagen maturation index was different in each of the four groups, bigger in group A with 0.87, group B with 0.66, group D with 0.57 and group C with 0.33 (p = 0.0000). Conclusion: The most prominent fibrosis promotion in the given meshes was found on Marlex® (polypropylene mesh) and the Parietex Composite® (non-biodegradable polyester); the collagen maturation index was higher in the Marlex® mesh, followed by Ultrapro®, Parietex Composite® and Vicryl® meshes.


Subject(s)
Animals , Polyesters/adverse effects , Polyglactin 910/adverse effects , Polypropylenes/adverse effects , Surgical Mesh/adverse effects , Collagen/adverse effects , Abdominal Wall/pathology , Polyesters/administration & dosage , Polyglactin 910/administration & dosage , Polypropylenes/administration & dosage , Time Factors , Fibrosis/etiology , Fibrosis/pathology , Materials Testing , Tissue Adhesions/etiology , Tissue Adhesions/pathology , Collagen/administration & dosage , Models, Animal , Abdominal Wall/surgery
7.
Acta cir. bras ; 33(9): 762-774, Sept. 2018. tab, graf
Article in English | LILACS | ID: biblio-973507

ABSTRACT

Abstract Purpose: To compare wound healing performed with cold blade (CSB) and ultrasonic harmonic scalpel (UHS) in the abdominal aponeurosis of rats. Methods: Eighty Wistar rats divided into two groups and underwent midline incision in the linea alba with cold blade and harmonic ultrasonic scalpel. Analysis were performed in subgroups of 10 animals after 3, 7, 14 and 21 days. Macroscopically was observed the presence of hematoma, infection, wound dehiscence, fistula and adherences. Microscopically were used collagen and immunohistochemical staining methods. Results: Macroscopic, complications showed no statistical difference. Immunohistochemical analysis for MMP-9 was more intense in UHS group (p<0.05). TGF β presented its lower expression in UHS group at 14 and 21 days, with no statistical difference at 3 and 7 days (p<0.05). α-AML expression appeared higher in UHS group after 14 days and remained similar in others (p<0.05). Collagen deposition had no change in type I, and increased in type III in UHS; at 7th day the deposition was higher in CSB group; at 14th was similar in both groups (p<0.001). Conclusion: UHS compared to the CSB has higher lesion area at the time of the incision; as well as it led to the delay of regeneration and scar maturation process.


Subject(s)
Animals , Male , Rats , Wound Healing/physiology , Collagen/physiology , Abdominal Wall/surgery , Surgical Wound/pathology , Surgical Instruments , Immunohistochemistry , Rats, Wistar , Models, Animal , Abdominal Wall/pathology , Tissue Array Analysis , Ultrasonic Surgical Procedures , Surgical Wound/physiopathology
8.
Int. braz. j. urol ; 44(4): 819-825, July-Aug. 2018. tab, graf
Article in English | LILACS | ID: biblio-954082

ABSTRACT

ABSTRACT Aims and Objectives: Polypropylene meshes have been increasingly adopted for correction of pelvic organ prolapse due to its lower recurrence rate when compared to surgeries without meshes. The study of the interaction of these materials with the host tissue may contribute to the development of materials with best biocompatibility and, consequently, less complication rates. Materials and Methods: The present study compares the inflammatory reaction of standard-weight (SW) and lightweight (LW) meshes (72 g/m216g/m2 respectively), implanted in the abdomen of 20 adult rats, which were euthanized in four or 30 days. Quantification of pro-inflammatory markers, IL-1 and TNF-α, and of metalloproteinases, MMP2 and MMP3, were carried out through immunohistochemistry with AxioVision® software. Results: There were no significant differences in the quantification of IL-1 and TNF-α in LW versus SW meshes. However, IL-1 quantification increased along time (30 days >4 days, p=0.0269). Also, MMP-2 quantification was similar to SW and LW and both presented a significant increase along time (30 days >4 days, p <0.0001). MMP-3 quantification also showed no difference between the SW and LW groups, but increased along time (30 days >4 days, p=0.02). Conclusions: Mesh's density did not influence the quantification of pro-inflammatory cytokines IL-1 and TNF-α and metalloproteinases 2 and 3. The increased expression of IL-1, MMP-2 and MMP-3 over time could represent a longstanding inflammatory response after PP mesh implantation. Possibly, the occurrence of adverse events following PP prosthetic implants can be influenced by other factors, not solely related to the amount of implanted material.


Subject(s)
Animals , Female , Rats , Polypropylenes/adverse effects , Surgical Mesh/adverse effects , Interleukin-1/analysis , Tumor Necrosis Factor-alpha/analysis , Matrix Metalloproteinase 3/analysis , Matrix Metalloproteinase 2/analysis , Subcutaneous Tissue/pathology , Time Factors , Wound Healing , Biocompatible Materials/adverse effects , Materials Testing , Immunohistochemistry , Reproducibility of Results , Foreign-Body Reaction/chemically induced , Foreign-Body Reaction/pathology , Collagen/analysis , Abdominal Wall/pathology , Subcutaneous Tissue/drug effects
9.
An. bras. dermatol ; 93(1): 111-113, Jan.-Feb. 2018. tab, graf
Article in English | LILACS | ID: biblio-887138

ABSTRACT

Abstract: Primary cutaneous amyloidosis is limited to the skin without involving any other tissue. Nodular amyloidosis is rare, and atrophic nodular cutaneous amyloidosis is even rarer. We describe the fourth case of atrophic nodular cutaneous amyloidosis by searching PubMed databases. A 52-year-old female presented to our hospital with a 2-year history of orange papules and nodules without subjective symptom on her right abdomen. Review of systems was negative. Atrophic nodular amyloidosis may progress to primary systemic disease in up to 7% of cases. Because our patient had no systemic involvement, she was diagnosed with atrophic nodular cutaneous amyloidosis based on characteristic symptoms and histopathologic examination. Routine follow-up for this patient is necessary to detect any potential disease progression.


Subject(s)
Humans , Female , Middle Aged , Skin Diseases/pathology , Amyloidosis/pathology , Atrophy/pathology , Skin Diseases/diagnosis , Abdominal Wall/pathology , Amyloidosis/diagnosis
10.
Clinics ; 73: e319, 2018. tab, graf
Article in English | LILACS | ID: biblio-952786

ABSTRACT

OBJECTIVES: Interest in elucidating the etiology of hernias has encouraged countless studies of musculoaponeurotic structures in individuals with and without hernias. Studies of hernia patients have firmly demonstrated a correlation between hernias and collagen alterations in their fascia. Diastasis recti is an increased width of the abdominal midline that is exclusively composed of interlacing aponeurotic expansions of the anterolateral abdominal muscles. The condition is common among women undergoing abdominoplasty, and many factors, not only mechanical, play a role. The goal of this study is to evaluate and compare collagen type I and III levels in the midline fascia of women with and without diastasis recti to report their possible influence on this condition. METHODS: This is a case-control study nested within a surgical cohort of 18 women with diastasis recti and 18 women without the condition (cases and controls, respectively). Fascia from the midline of the abdominal wall was collected and analyzed through immunohistochemistry using polyclonal antibodies to collagen type I and III. RESULTS: Both type I and type III collagen were less abundant in women with diastasis recti than in those without the condition, and the difference was statistically significant (p<0.001). CONCLUSION: Low collagen type I and type III levels in the midline of the abdominal wall may play a key role in the development of diastasis recti.


Subject(s)
Humans , Female , Adult , Prune Belly Syndrome/metabolism , Collagen Type I/analysis , Collagen Type III/analysis , Abdominal Wall/pathology , Prune Belly Syndrome/pathology , Immunohistochemistry , Lipectomy , Case-Control Studies
11.
Acta cir. bras ; 32(8): 626-632, Aug. 2017. tab, graf
Article in English | LILACS | ID: biblio-886226

ABSTRACT

Abstract Purpose: To evaluate the effectiveness of sodium hyaluronate, sesame oil, honey, and silver nanoparticles in preventing of postoperative surgical adhesion formation. Methods: Forty male Wistar rats were randomly assigned into five groups with eight rats in each group including control, hyaluronate, sesame, honey and silver groups. After two weeks the animals underwent laparotomy and were evaluated by two different blinded surgeons for severity of adhesions based on the two different classification scoring systems including Nair classification and cumulative adhesion scoring scale. Results: The scores of severity of adhesions in the hyaluronate and sesame groups were significantly lower than the control group based on the Nair classification (both P-values = 0.02), however based on the cumulative adhesion scoring scale just the score of severity of adhesions in the hyaluronate group was significantly lower than the control group (P-value = 0.02). In the hyaluronate group the severity of adhesions was decreased by 48% based on the cumulative adhesion scoring scale. Conclusions: Sodium hyaluronate and sesame oil may have a significant effect in preventing postoperative surgical adhesion formation.


Subject(s)
Animals , Male , Postoperative Complications/prevention & control , Silver/therapeutic use , Sesame Oil/therapeutic use , Metal Nanoparticles/therapeutic use , Honey , Hyaluronic Acid/therapeutic use , Postoperative Complications/pathology , Time Factors , Severity of Illness Index , Random Allocation , Tissue Adhesions/pathology , Reproducibility of Results , Rats, Wistar , Abdominal Wall/surgery , Abdominal Wall/pathology , Anti-Inflammatory Agents/therapeutic use
13.
Acta cir. bras ; 31(11): 714-719, Nov. 2016. graf
Article in English | LILACS | ID: biblio-827665

ABSTRACT

ABSTRACT PURPOSE: To analysis the effects of passive smoking on the microstructure of tissues of the abdominal wall regarding microcirculation, using histopathological study of the tobacco exposed rats. METHODS: Twenty four male Wistar rats were divided in Control Group (CG = 8 animals) and Exposition Groups (EG = 16 animals). EG was exposed to cigarette smoke 4x/day for 120 days, while CG was preserved from exposure. Food, water and housing were similar for both groups. After 120 days, urine samples were collected before necropsy to analyze cotinine levels (ng/mL) in urine and blinded histopathological analysis of the abdominal wall performed to count arteries and veins in dermal and muscular fascia layer. RESULTS: No difference in weight was observed between both groups (P>0.05). Cotinine concentration was significantly higher in EG (P<0.05). In dermal layer, the average of vessels per animal was 8.72 (IC95%: 8.31-9.13) for CG and 11,23 (IC95%: 10.09-12.38) for EG. In muscular fascia layer the average of vessels per animal was 17.97 (IC95%: 15.79-20.15) for CG, whereas the average for EG was of 14,85 (IC95%: 12.71-17.01) (P<0.05). CONCLUSION: Exposition to passive smoking may cause increase in the number of vessels in dermal layer, with the opposite effects at the muscular fascia layer.


Subject(s)
Animals , Male , Rats , Tobacco Smoke Pollution/adverse effects , Smoking/adverse effects , Cotinine/adverse effects , Abdominal Wall/blood supply , Microcirculation , Rats, Wistar , Cotinine/urine , Abdominal Wall/pathology
14.
Acta cir. bras ; 31(6): 371-376, tab, graf
Article in English | LILACS | ID: lil-785014

ABSTRACT

ABSTRACT PURPOSE: To develop an experimental model for incisional hernias and to compare morphological and functional aspects of hernia repairs by suture, polypropylene mesh and collagen mesh. METHODS: A defect measuring 7cm x 2cm was created in the anterior abdominal of 28 New Zealand male rabbits, divided into four groups (n = 7): (1) control, (2) suture of the anterior sheath of the rectus abdominal muscle, (3) setting of polypropylene mesh, and (4) setting of collagen mesh. On the 90th postoperative day, the animals were examined to verify the presence of incisional hernia. Samples of abdominal wall and scar were collected for histological study. RESULTS: Incisional hernia was identified in 85.7% of the control group, 57.1% of the suture group, 42.9% of the collagen mesh group, and none in the polypropylene mesh group (p = 0.015). Mesh exposure could be identified in 71.4% of the animals in group 3 and in no animal in group 4 (p = 0.021). The polypropylene mesh is effective in the treatment of abdominal wall defects, causing an intense inflammatory reaction. CONCLUSION: The collagen mesh is biocompatible, producing a minimal inflammatory reaction, but fails in the treatment of abdominal wall defects.


Subject(s)
Animals , Male , Rabbits , Surgical Mesh , Sutures/adverse effects , Abdominal Wall/surgery , Incisional Hernia/surgery , Polypropylenes/adverse effects , Postoperative Complications/pathology , Prostheses and Implants , Prostheses and Implants/adverse effects , Surgical Mesh/adverse effects , Giant Cells, Foreign-Body/pathology , Collagen/therapeutic use , Models, Animal , Abdominal Wall/pathology , Inflammation/pathology
15.
Rev. bras. cir. plást ; 31(2): 178-185, 2016. ilus
Article in English, Portuguese | LILACS | ID: biblio-1557

ABSTRACT

INTRODUÇÃO: A abdominoplastia é o terceiro procedimento mais realizado em cirurgia plástica. Na intenção de evitar complicações cirúrgicas, foi feito o estudo da artéria ilíaca circunflexa superficial do abdome (AICS), investigando a importância da sua preservação nestas cirurgias, como um dos fatores de alta importância na prevenção das necroses. MÉTODOS: O presente estudo anatômico prospectivo foi realizado no Serviço de Cirurgia Plástica do Hospital Agamenon Magalhães. Trinta e três pacientes foram submetidos à dermolipectomia abdominal à Pitanguy, com os retalhos cirúrgicos ressecados sendo submetidos a estudos hemodinâmicos para análise do território anatômico irrigado pela AICS. RESULTADOS: Foram operados 82 pacientes, sendo selecionados 33 que preencheram os critérios de inclusão para este estudo, seis (18,9%) foram excluídos por motivos técnicos. O grupo de pacientes em estudo apresentou faixa etária entre 23 e 49 anos (36,6 ± 7,5). O Índice de Massa Corporal variou de 22,0 a 30,5 (24,9 ± 2,1). O peso das peças cirúrgicas ressecadas variou de 450 a 1010 gramas (623,1 ± 141,5), o teste de Pearson entre IMC e peso das peças demonstrou importante correlação r = 0,91 e r2 = 0,83. Trinta e dois eram femininos (97%) e um masculino (3%). Uma paciente era portadora de hipertensão arterial sistêmica (3%). Vinte e sete eram pardos (81,8%), dois brancos (6,1%), três negros (9,1%) e um da raça indígena (3,0%). Nos estudos hemodinâmicos, as imagens e filmes obtidos demonstraram que a injeção do contraste iodado na AICS foi considerada adequada, compatível com o objetivo do trabalho em 25 (92%) pacientes e inadequada em dois (8%) pacientes. CONCLUSÃO: Os resultados hemodinâmicos deste estudo levam à conclusão que a preservação da AICS do abdome nas miniabdominoplastias tem relevante importância na prevenção das necroses da parede abdominal.


complications, a study of the superficial circumflex iliac artery of the abdomen (SCIA) was carried out to investigate the importance of this artery preservation in abdominoplasties as one of the high importance factors to prevent necrosis. METHODS: This prospective study was carried out at the Plastic Surgery Service of the Agamenon Magalhaes Hospital. We included 33 patients who underwent abdominoplasty using Pitanguy's technique where the resected surgical flaps underwent hemodynamic studies to analyze the anatomical area irrigated by SCIA. RESULTS: A total of 82 patients underwent surgery, of them 33 met the study inclusion criteria, and 6 (18.9%) were excluded for technical reasons. Patients' age ranged from 23 and 49 years (36.6±7.5), their body mass index (BMI) ranged from 22.0 to 30.5 (24.9 ± 2.1), and weight of resected surgical specimens ranged from 450 to 1010 grams (623.1 ± 141.5). Pearson's test between BMI and weight of surgical specimens showed significant correlation r = 0.91 and r2 = 0,83. We included in the study 32 women (97%) and 1 man (3%). One patient had hypertension (3%). Of the sample, 27 patients were pardo (81.8%), 2 white (6.1%), 3 black (9.1%) and 1 native south American (3.0%). In hemodynamic studies, images and videos obtained showed that injection of iodinated contrast in SCIA were considered adequate, and consistent with the objective of this study in 25 (92%) patients and inadequate for 2 (8%) patients. CONCLUSION: Hemodynamic results of our study indicated that preservation of SCIA of the abdomen in mini-abdominoplasties is important to prevent necrosis of abdominal wall.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , History, 21st Century , Surgery, Plastic , Surgical Flaps , Prospective Studies , Evaluation Study , Abdominal Wall , Abdomen , Abdominoplasty , Hemodynamics , Iliac Artery , Anatomy , Necrosis , Surgery, Plastic/methods , Surgical Flaps/surgery , Abdominal Wall/anatomy & histology , Abdominal Wall/surgery , Abdominal Wall/pathology , Abdominoplasty/methods , Abdomen/anatomy & histology , Abdomen/surgery , Iliac Artery/anatomy & histology , Iliac Artery/surgery , Iliac Artery/pathology , Anatomy/methods , Necrosis/pathology , Necrosis/prevention & control
16.
Acta cir. bras ; 30(10): 691-703, tab
Article in English | LILACS | ID: lil-764391

ABSTRACT

PURPOSE: To evaluate and compare clinical and inflammatory responses to the surgical trauma caused by cholecystectomy via several access approaches: single-port umbilical incision (SILS), transvaginal natural orifice transluminal endoscopic surgery (NOTES), laparoscopy, and Laparotomy.METHODS: Twenty-eight female pigs were equally divided into four groups and submitted to cholecystectomy by single-port umbilical incision, transvaginal NOTES, laparoscopy, or Laparotomy. An additional five animals served as controls (sham group). Animals were monitored perioperatively regarding anesthesia and surgical procedure times, as well as for the presence of complications. Postoperatively, they were evaluated regarding time to ambulation and feeding, and the presence of clinical events. Procalcitonin, C-reactive protein (CRP), and AQUI feron-gamma (IFN-γ) measurements were performed before surgery and immediately, two days, and seven days after surgery. Animals were sacrificed and necropsied at seven days after surgery.RESULTS: All procedures were successfully performed as proposed in each group. Only minor complications, such as gallbladder perforation and bleeding from the liver bed, were observed during surgery in all groups. The vaginal NOTES group showed higher anesthesia and surgical procedure times compared to the other groups (p<0.001). No other between-group differences in perioperative or postoperative times, clinical evolution, or serum inflammatory markers were observed. Only adhesions were found on necropsy, with no differences between groups.CONCLUSION: The single-port umbilical and transvaginal NOTES access approaches were feasible and safe compared to laparoscopic and laparotomy for cholecystectomy.


Subject(s)
Animals , Female , Cholecystectomy/adverse effects , Cholecystectomy/methods , Natural Orifice Endoscopic Surgery/adverse effects , Natural Orifice Endoscopic Surgery/methods , Systemic Inflammatory Response Syndrome/etiology , Abdominal Wall/pathology , Abdominal Wall/surgery , C-Reactive Protein/analysis , Calcitonin/blood , Intraoperative Complications , Interferon-gamma/blood , Operative Time , Postoperative Complications , Protein Precursors/blood , Reproducibility of Results , Swine , Systemic Inflammatory Response Syndrome/pathology , Tissue Adhesions/pathology , Umbilicus/surgery , Vagina/surgery
17.
Acta cir. bras ; 30(10): 686-690, tab, graf
Article in English | LILACS | ID: lil-764397

ABSTRACT

PURPOSE:Toevaluate the effects of nitrofurazone on the correction of abdominal wall defect treated with polypropylene mesh involved by fibrous tissue in rats.METHODS: A defect in the abdominal wall was created and corrected with polypropylene mesh in 20 rats. They were randomly distributed into four groups: control, fibrous mesh, nitrofurazone and nitrofurazone dip in the mesh. Euthanasia was performed in 21 post-operative days. The healing process was analyzed regarding the meshes and macroscopic and microscopic aspects.RESULTS:All animals had adhesions. However, no statistically significant difference (p>0.05) when compared between groups. Similarly microscopic analysis, in which there was no statistical significance level for the evaluated parameters such as mono and polymorphonuclear lymphocytes, granuloma, fibrosis, necrosis and collagen proliferation.CONCLUSION:There was no significant effect on the abdominal wall defect repair with polypropylene mesh surrounded by fibrous tissue when dipped in nitrofurazone 2%.


Subject(s)
Animals , Abdominal Wall/surgery , Anti-Infective Agents/pharmacology , Nitrofurazone/pharmacology , Polypropylenes/therapeutic use , Surgical Mesh , Abdominal Wall/pathology , Hernia, Ventral/surgery , Herniorrhaphy/methods , Materials Testing , Random Allocation , Rats, Wistar , Reproducibility of Results , Tissue Adhesions/pathology , Wound Healing/drug effects
18.
Acta cir. bras ; 30(2): 134-142, 02/2015. graf
Article in English | LILACS | ID: lil-741023

ABSTRACT

PURPOSE: To investigate the changes induced by DisBa-01 on repair of wound healing after induced incisional hernia (IH) in rats. METHODS: Thirty two male albino rats were submitted to IH and divided into four experimental groups: G1, placebo control; G2, DisBa-01-treated; G3, anti-αvβ3 antibodies-treated and G4, anti-α2 antibodies-treated. Histological, biochemical and extracellular matrix remodeling analysis of abdominal wall were evaluated. RESULTS: After 14 days, 100% of the G2 did not present hernia, and the hernia ring was closed by a thin membrane. In contrast, all groups maintained incisional hernia. DisBa-01 also increased the number macrophages and fibroblasts and induced the formation of new vessels. Additionally, MMP-2 was strongly activated only in G2 (p<0.05). Anti- αvβ3-integrin antibodies produced similar results than DisBa-01 but not anti-α2 integrin blocking antibodies. CONCLUSION: DisBa-01 has an important role in the control of wound healing and the blocking of this integrin may be an interesting therapeutically strategy in incisional hernia. .


Subject(s)
Animals , Male , Disintegrins/pharmacology , Hernia, Ventral/pathology , /antagonists & inhibitors , Platelet Aggregation Inhibitors/pharmacology , Wound Healing/drug effects , Abdominal Wall/pathology , Collagen/analysis , Collagen/drug effects , Disease Models, Animal , Fibroblasts/drug effects , Hernia, Ventral/drug therapy , Hernia, Ventral/surgery , /analysis , /physiology , Random Allocation , Rats, Wistar , Reproducibility of Results , Time Factors , Treatment Outcome
19.
Rev. latinoam. enferm ; 23(1): 90-97, Jan-Feb/2015. tab, graf
Article in English | LILACS, BDENF | ID: lil-742018

ABSTRACT

OBJECTIVE: To assess the knowledge of nurses involved in the care of oncology patients in a public university hospital, regarding breast cancer and hereditary breast cancer, and to verify the use of such knowledge in their daily practice. METHODS: This is a descriptive cross-sectional study. Data were obtained through a structured, self-administered questionnaire. Out of 154 nurses, 137 (88.9%) agreed to participate in the study. Two questionnaires were excluded such that 135 questionnaires were analyzed. RESULTS: The global percentage of correct answers was not associated with age (p=0.173) or degree/specialization (p=0.815). Questions were classified into categories. In categories involving knowledge of established breast cancer risk factors and indicators of hereditary breast cancer, the rate of correct answers was 65.8% and 66.4%, respectively. On the practice of genetic counseling, 40.7% of those interviewed were not sure about the definition of genetic counseling and 78.5% reported never having identified or referred a patient at genetic risk for specialized risk assessment. Practice of educational actions regarding this subject was reported by 48.5% of those interviewed. CONCLUSION: This study reinforces the need to develop qualifying actions for nurses, so that strategies to control breast cancer become effective in their health care practice. .


OBJETIVO: avaliar os conhecimentos de enfermeiros envolvidos nos cuidados de pacientes oncológicos em um hospital público universitário, em relação ao câncer de mama e ao câncer de mama hereditário e verificar o uso de tais conhecimentos em sua prática diária. MÉTODOS: este é um estudo transversal. Os dados foram obtidos por meio de um questionário estruturado autoaplicado. De um total de 154 enfermeiros convidados a participar do estudo, 137 (88,9%) concordaram. Dois questionários foram excluídos, totalizando 135 analisados. RESULTADOS: a porcentagem global de respostas corretas não estava associada à idade (p = 0,173) ou à formação/especialização (p = 0,815). As perguntas foram classificadas em categorias. Nas categorias que abrangiam conhecimentos relacionados aos fatores de risco estabelecidos para o câncer de mama e aos indicadores do câncer de mama hereditário, a taxa de respostas corretas foi de 65,8% e 66,4%, respectivamente. Em relação à prática de aconselhamento genético, 40,7% dos entrevistados não tinham certeza sobre a definição de aconselhamento genético, e 78,5% relataram nunca ter identificado ou encaminhado um paciente com risco genético para uma avaliação de riscos especializada. A prática de ações educativas em relação a esse tema foi relatada por 48,5% dos entrevistados. CONCLUSÃO: este estudo reforça a necessidade de desenvolver ações qualificadoras para enfermeiros de modo que as estratégias para o controle do câncer tornem-se eficientes em suas prática de cuidados de saúde. .


OBJETIVO: evaluar los conocimientos del personal de enfermería involucrado en el cuidado de los pacientes de oncología de un hospital universitario público, en relación con el cáncer de mama y el cáncer de mama hereditario, y verificar el uso de esos conocimientos en su práctica diaria. MÉTODOS: estudio descriptivo de corte transversal; los datos se obtuvieron mediante un cuestionario estructurado autoadministrado. De un total de 154 enfermeros/as, 137 (88,9%) aceptaron participar en el estudio. Se excluyeron dos cuestionarios, totalizando 135 cuestionarios analizados. RESULTADOS: el porcentaje global de respuestas correctas no se asoció con la edad (p=0,173) o título/especialización (p=0,815). Las preguntas fueron clasificadas en categorías. En las categorías que implican el conocimiento de los factores de riesgo establecidos del cáncer de mama y los indicadores del cáncer de mama hereditario, la tasa de respuestas correctas fue de 65,8% y 66,4%, respectivamente. En relación con la práctica del consejo genético, el 40,7% de los entrevistados/as no estaban seguros/as acerca de la definición de consejo genético y el 78,5% informó que nunca habían identificado o derivado a un paciente en situación de riesgo genético para una evaluación de riesgos especializada. La práctica de acciones educativas con respecto a este tema se reportó en el 48,5% de los entrevistados/as. CONCLUSIÓN: este estudio refuerza la necesidad de desarrollar acciones de calificación para el personal de enfermería, para que las estrategias de control del cáncer de mama sean efectivas en su práctica asistencial. .


Subject(s)
Animals , Female , Rats , Peritoneum/pathology , Tissue Adhesions/pathology , Abdominal Wall/pathology , Foreign-Body Reaction/pathology , Models, Biological , Rats, Wistar
20.
Rev. bras. cir. plást ; 30(2): 196-205, 2015. ilus, tab
Article in English, Portuguese | LILACS | ID: biblio-1004

ABSTRACT

Introdução: A correção da diástase dos músculos retos do abdome é realizada principalmente pela sua plicatura, procedimento que consome muito tempo cirúrgico. O objetivo deste estudo é avaliar a eficácia e o tempo necessário para a correção da diástase dos retos do abdome comparando a plicatura com sutura contínua em plano único à plicatura em dois planos. Método: Foram incluídas 20 mulheres com história de pelo menos uma gestação. Foram randomizadas em dois grupos, um submetido à plicatura dos retos do abdome em dois planos (controle) e outro à sutura em plano único contínuo (estudo) com mononylon 2-0. Mediu-se o tempo necessário para a realização de cada uma das técnicas. Para análise estatística, foram usados os testes não paramétricos de Mann-Whitney, Friedman e Wilcoxon, considerando estatisticamente significante p < 0,05. Todas as pacientes foram submetidas à ultrassonografia previamente à cirurgia, 3 semanas e 6 meses de pós-operatório. Resultados: A plicatura do grupo estudo mostrou-se tão eficaz quanto à do grupo controle, mantendo seu resultado em longo prazo, apresentando diferença estatisticamente significante (p = 0,018) na comparação das medidas pré e pós-operatórias. No grupo estudo, porém, a plicatura consumiu menor tempo cirúrgico para ser realizada, também com diferença estatisticamente significante (p = 0,002). Conclusão: Com este estudo, pode ser concluído que tanto a sutura em dois planos como a em plano único contínuo são eficazes na correção da diástase dos retos do abdome e mantêm o resultado por longo tempo. Concluiu-se também que a técnica de sutura contínua demanda menor tempo para ser realizada.


Introduction: The correction of diastasis of the rectus abdominis muscles is primarily performed using the plication technique, which involves a surgical procedure. To evaluate the efficacy and the surgical time necessary to correct diastasis of the rectus abdominis muscles using plication and sutures in one continuous or two planes. Method: Twenty women with at least one pregnancy were included in the study. The study participants were randomized into two groups: the control group was subjected to plication in two planes, and the experimental group was subjected to plication using suture in one continuous plane with mono-nylon 2-0. The time required to perform each of these techniques was measured. For statistical analysis, the nonparametric Mann-Whitney test, Friedman test, and Wilcoxon test were used, and p-values of < 0.05 were considered statistically significant. All patients underwent ultrasonography before surgery, and at 3 weeks and 6 months postoperatively. Results: The plication technique was similarly effective in the two groups, achieving a long-term surgical outcome; however, the differences in the ultrasound measurements in the pre- and postoperative periods were statistically significant (p = 0.018). In addition, plication was performed in a significantly shorter time in the experimental group (p = 0.002). Conclusion: Sutures in one continuous plane and in two planes were effective in correcting diastasis of the rectus abdominis muscles, with the maintenance of a long-term surgical outcome. In addition, the continuous suture technique can be performed in a shorter time.


Subject(s)
Humans , Female , Adult , Middle Aged , History, 21st Century , Sutures , Efficacy , Suture Techniques , Abdominal Muscles , Rectus Abdominis , Evaluation Study , Abdominal Wall , Abdomen , Abdominoplasty , Amylases , Efficacy/methods , Suture Techniques/adverse effects , Suture Techniques/standards , Abdominal Muscles/surgery , Abdominal Muscles/pathology , Rectus Abdominis/surgery , Rectus Abdominis/pathology , Abdominal Wall/surgery , Abdominal Wall/pathology , Abdominoplasty/adverse effects , Abdominoplasty/methods , Abdomen/surgery , Abdomen/pathology , Amylases/therapeutic use
SELECTION OF CITATIONS
SEARCH DETAIL