ABSTRACT
Objetivo: Reportar casos de linfadenoma sebáceo, un tumor raro, localizado principalmente en la glándula parótida, con muy pocos casos descritos en la literatura. Casos clínicos: Presentamos 2 casos de esta rara afección, tratados en el Hospital Universitario Miguel Servet de Zaragoza, de enero de 2010 a diciembre de 2014. El diagnóstico, tanto por imagen como citológico, es difícil debido a su baja prevalencia y a la gran variedad de tumores de glándula parótida que existen. En los 2 casos presentados ha sido necesaria la exéresis para llegar al diagnóstico. El tratamiento curativo consiste en la exéresis completa de la tumoración.
Aim: To report a rare parotid tumour: sebaceous lymphadenoma, with very few cases reported in the literature. Cases report: We present 2 cases of lymphadenoma sebaceous of the parotid gland treated by surgery at University Hospital Miguel Servet of Zaragoza between January 2010 and December 2014. The diagnosis, both radiological and cytological, is difficult because of their low prevalence and the great variety of parotid gland tumors existent. In our 2 cases described, excision has been required for diagnosis. A complete excision of the tumor is required for curative treatment.
Subject(s)
Humans , Aged , Aged, 80 and over , Parotid Gland/pathology , Parotid Neoplasms/surgery , Adenolymphoma/surgery , Parotid Gland/surgery , Parotid Neoplasms/diagnosis , Adenolymphoma/diagnosis , Retrospective StudiesABSTRACT
Recently, an oncocytic variant of papillary thyroid carcinoma with lymphocytic stroma, called Warthin like tumor, has been described. Its evolution is similar to the usual papillary carcinoma. We report a 61 years old female with a multinodular goiter and a predominant nodule in the right lobe. A fine needle aspiration biopsy was compatible with a papillary thyroid carcinoma. A total thyroidectomy was performed and the pathological examination revealed a Warthin tumor of 2.2 cm. The patient was treated posteriorly with radioiodine and after six months of follow up, there is no evidence of disease...
Subject(s)
Humans , Female , Middle Aged , Carcinoma, Papillary/surgery , Carcinoma, Papillary/diagnosis , Thyroid Neoplasms/surgery , Thyroid Neoplasms/diagnosis , Thyroidectomy , Adenolymphoma/diagnosis , Diagnosis, DifferentialABSTRACT
Warthin's tumor also known as papillary cystadenoma lymphomatosum is a common benign salivary gland neoplasm that occurs exclusively in parotid gland. Rarely, the tumor can undergo carcinomatous or lymphomatous transformation of epithelial or lymphoid component, respectively. Herein, we describe a case of 55-year-old female who had undergone parotidectomy for a rapidly growing tumor in the right parotid gland. The case was diagnosed as mucoepidermoid carcinoma developed in a setting of Warthin's tumor based on the histomorphology, special staining characters, and immunohistochemical findings. The pathogenesis and differential diagnoses of such rare malignancy has been discussed briefly.
Subject(s)
Adenolymphoma/complications , Adenolymphoma/diagnosis , Adenolymphoma/pathology , Adenolymphoma/surgery , Carcinoma, Mucoepidermoid/complications , Carcinoma, Mucoepidermoid/diagnosis , Carcinoma, Mucoepidermoid/pathology , Carcinoma, Mucoepidermoid/surgery , Female , Histocytochemistry , Humans , Microscopy , Middle Aged , Parotid Gland/pathology , Parotid Gland/surgery , Parotid Neoplasms/diagnosis , Parotid Neoplasms/pathology , Parotid Neoplasms/surgeryABSTRACT
Warthin tumor is a well-recognized benign salivary gland neoplasm consisting of an epithelial as well as a lymphoid component. Malignant transformation in Warthin tumor is rare and its reported incidence is up to 1%. The more common types of carcinomas described in Warthin tumor are the squamous and mucoepidermoid types, with high-grade adenocarcinoma being extremely rare. A high-grade adenocarcinoma (ductal type) arising in the Warthin tumor in a 72-year-old man is presented for its rarity and diagnostic difficulties.
Subject(s)
Adenocarcinoma/diagnosis , Adenocarcinoma/pathology , Adenolymphoma/complications , Adenolymphoma/diagnosis , Adenolymphoma/pathology , Aged , Histocytochemistry , Humans , Immunohistochemistry , Keratin-7/analysis , Male , Microscopy , Parotid Gland/pathology , Parotid Neoplasms/diagnosis , Parotid Neoplasms/pathology , Biomarkers, Tumor/analysisABSTRACT
OBJETIVO: Relatar as características clínicas, tratamento e complicações.dos tumores de Warthin. MÉTODOS: Estudo retrospectivo com 70 pacientes submetidos à ressecção de cistoadenoma papilífero linfomatoso,. Variáveis analisadas: idade, sexo, etnia, presença ou não de tabagismo, sítio primário do tumor, tamanho do tumor em centímetros, presença de bilateralidade, tipo de operação, multicentricidade, complicações do tratamento, presença de recidiva no seguimento e tempo de seguimento.. RESULTADOS: Quarenta e quatro pacientes (62,8 por cento) eram do sexo masculino e 26 (37,2 por cento), do sexo feminino, com média etária de 56,7 anos, O tabagismo estava presente em 55 (78,6 por cento) pacientes, (94,3 por cento) dos tumores eram unilaterais e quatro (5,7 por cento) bilaterais, com tamanho médio de 4,1cm ao exame físico. As complicações foram 14 (19 por cento) casos de paresia e/ou paralisia facial, seroma em 10 (13,8 por cento), síndrome de Frey em três (4 por cento), hematoma em dois (2,7 por cento) e infecção de ferida operatória em um (1,5 por cento) caso. CONCLUSÃO: O tumor de Warthin tem maior incidência no sexo masculino, em tabagistas e localização unilateral predominante na glândula parótida. A parotidectomia superficial com preservação do nervo facial mostrou-se eficaz em 100 por cento casos. As complicações encontradas foram paresias ou paralisias transitórias, seroma, síndrome de Frey, hematoma e infecção de ferida operatória.
OBJECTIVE: To report the clinical characteristics, treatment and complication of Warthin tumors. METHODS: we conducted a retrospective study of 70 patients undergoing resection of papillary lymphomatous cystadenoma. Variables: age, sex, ethnicity, presence or absence of smoking, primary site of tumor, tumor size in cm, presence of bilateral tumor, type of operation, multicentricity, treatment complications, recurrence and follow up. RESULTS: Forty-four patients (62.8 percent) were male and 26 (37.2 percent) female, with a mean age of 56.7; smoking was present in 55 (78.6 percent) patients; 66 (94.3 percent) tumors were unilateral and four (5.7 percent) bilateral, with an average size of 4.1 cm on physical examination. The complications were 14 (19 percent) cases of facial paresis and / or paralysis, seroma in 10 (13.8 percent), Frey's syndrome in three (4 percent), hematoma in two (2.7 percent) and wound infection in one (1.5 percent) case. CONCLUSIONS: Warthin tumors have a higher incidence in male smokers and predominantly unilateral location of the parotid gland. Superficial parotidectomy with preservation of facial nerve was effective in 100 percent cases. Complications were transient paresis or paralysis, seroma, Frey syndrome, hematoma and wound infection.
Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Adenolymphoma , Parotid Neoplasms , Adenolymphoma/diagnosis , Adenolymphoma/surgery , Parotid Neoplasms/diagnosis , Parotid Neoplasms/surgery , Retrospective StudiesABSTRACT
Malignant transformation of the epithelial component of Warthin's tumor is extremely rare. We describe our experience of mucoepidermoid carcinoma arising in Warthin's tumor of the parotid gland in a 35 year old female. The tumor removed from the parotid region was well encapsulated and histologically comprised ofmucoepidermoid carcinoma along with areas of Warthin's tumor. The pathogenesis and differential diagnosis of this rare occurrence have been discussed.
Subject(s)
Adenolymphoma/diagnosis , Adult , Carcinoma, Mucoepidermoid/diagnosis , Diagnosis, Differential , Female , Humans , Neoplasms, Second Primary/diagnosis , Parotid Neoplasms/diagnosisABSTRACT
Papillary Cystadenoma Lymphomatosum or Warthin's tumour is a unique neoplasm arising almost exclusively in the parotid salivary gland and is composed of oncocytic epithelium with a prominent lymphoid infiltrate. The tumor is usually asymptomatic and may be associated with varying degrees of pain not necessarily an indication of malignant transformation in the tumour. The tumour is managed easily by surgical excision. This article presents a typical case arising in the right parotid gland of a 73-year-old male with review of literature of this rare tumour.
Subject(s)
Adenolymphoma/diagnosis , Aged , Diagnosis, Differential , Humans , Male , Parotid Neoplasms/diagnosisABSTRACT
Se presenta el caso de un paciente de 22 años, portador de SIDA, con masa quística en la glándula parótida derecha y tumor de Warthin adyacente
Subject(s)
Humans , Male , Adult , Adenolymphoma/diagnosis , HIV/immunology , Parotid Neoplasms/etiology , Salivary Glands/pathology , Acquired Immunodeficiency Syndrome/complicationsABSTRACT
La biopsia por aspiración con aguja final de glándula saliva es un procedimiento fácil, seguro y económico que en muchas circunstancias permite un diagnóstico rápido con molestias mínimas para el paciente y con sensibilidad de 81-100 por ciento y especificidad de 94-100 por ciento. En este trabajo revisamos 237 biopsias por aspiración con aguja fina de glándula salival realizadas en un periodo de ocho años en el Instituto Nacional de Cancerología (INCan), México. En 185 pacientes se obtuvieron aspirados satisfactorios y en 144 casos de efectuó correlación con diagnóstico de histopatología. Se encontraron 65 (45 por ciento) verdaderos positivos, 62 (43 por ciento) verdaderos negativos, 11 (8 por ciento falsos negativos, seis (4 por ciento) falsos positivos. La sensibilidad fue de 85.52 por ciento, la especificidad de 91.17 por ciento, el valor predictivo positivo de 91.54 por ciento, el valor predictivo negativo de 84.93 por ciento y la eficiencia de 88.19 por ciento (p< 0.001). Nuestros resultados fueron similares a los obtenidos en 14 series publicadas previamente de biopsia por aspiración con aguja fina de glándula salival
Subject(s)
Humans , Male , Female , Aged , Adenolymphoma/diagnosis , Adenolymphoma/pathology , Biopsy, Needle/instrumentation , Salivary Gland Diseases/diagnosis , Salivary Gland Diseases/pathology , Salivary Glands/pathology , Salivary Gland Neoplasms/diagnosis , Salivary Gland Neoplasms/pathology , Sensitivity and SpecificitySubject(s)
Humans , Male , Female , Adenolymphoma/diagnosis , Parotid Gland/surgery , Histological TechniquesABSTRACT
Os autores analisam 45 casos de pacientes portadores de tumor de Warthin, diagnosticados e tratados no Servico de Cirurgia de Cabeca e Pescoco do Instituto Nacional do Cancer-RJ, no periodo de 1972 a 1989. O proposito deste trabalho foi analisar os dados referentes a cor, idade, sexo e intervalo diagnostico, correlacionando-os com o tratamento efetuado, assim como com as complicacoes advindas deste tratamento e os indices de recorrencia local. Todos os pacientes foram tratados com cirurgia exclusiva, com apenas duas variantes tecnicas: parotidectomia total e parotidectomia superficial.A parotidectomia superficial se mostrou a apcao terapeutica mais adequada para a maioria dos casos e as complicacoes advindas da cirurgia obtiveram evolucao benigna,apenas com tratamento conservador. Os indices de recorrencia local foram muito baixos, confirmando os relatos da literatura internacional.
Subject(s)
Humans , Adenolymphoma , Parotid Neoplasms , Adenolymphoma/diagnosis , Adenolymphoma/surgery , Age Factors , Postoperative Complications , Retrospective Studies , Sex FactorsABSTRACT
A case of papillary cystadenoma of the gallbladder is described, in which the diagnosis was established by ultrasonography. The role of this technique in the investigation of gallbladder disease is briefly discussed