Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 17 de 17
Filter
1.
Arq. bras. cardiol ; 117(3): 512-517, Sept. 2021. tab
Article in English, Portuguese | LILACS | ID: biblio-1339177

ABSTRACT

Resumo Fundamentos A síndrome de Heyde é a associação de estenose aórtica importante com episódio de sangramento gastrointestinal por lesões angiodisplásicas. Pouco é conhecido sobre os fatores associados a novos sangramentos e desfechos em longo prazo. Além disso, a maioria dos dados é restrita a relatos de casos e pequenas séries. Objetivo Avaliar o perfil clínico, laboratorial e ecocardiográfico de pacientes com síndrome de Heyde submetidos a intervenção valvar ou tratamento medicamentoso. Métodos Coorte prospectiva de 24 pacientes consecutivos entre 2005 e 2018. Foram avaliados dados clínicos, laboratoriais, ecocardiográficos e relacionados à intervenção valvar e a desfechos após o diagnóstico. Valor de p<0,05 foi considerado estatisticamente significante. Resultados Metade dos 24 pacientes apresentou sangramento com necessidade de transfusão sanguínea na admissão. Angiodisplasias foram encontradas mais frequentemente no cólon ascendente (62%). Intervenção valvar (cirúrgica ou transcateter) foi realizada em 70,8% dos pacientes, e 29,2% foram mantidos em tratamento clínico. Novos episódios de sangramento ocorreram em 25% dos casos, e não houve diferença entre os grupos clínico e intervenção (28,6 vs. 23,5%, p=1,00; respectivamente). A mortalidade no seguimento de 2 e 5 anos foi de 16% e 25%, sem diferença entre os grupos (log-rank p = 0,185 e 0,737, respectivamente). Conclusões Pacientes com síndrome de Heyde tiveram alta taxa de sangramento com necessidade de transfusão sanguínea na admissão, sugerindo ser uma doença grave e com risco elevado de mortalidade. Não encontramos diferenças entre os grupos submetidos ao tratamento clínico e à intervenção valvar em relação a taxas de ressangramento e mortalidade tardia.


Abstract Background Heyde's syndrome is the association of severe aortic stenosis with episodes of gastrointestinal bleeding due to angiodysplastic lesion. Little is known about the factors associated with new episodes of bleeding and long-term outcomes. Furthermore, most data are restricted to case reports and small case series. Objective To assess the clinical, laboratory and echocardiography profile of patients with Heyde's syndrome who underwent valve intervention or drug therapy. Methods Prospective cohort of 24 consecutive patients from 2005 to 2018. Clinical, laboratory and echocardiography data were assessed, as well as those related to valve intervention and outcomes after diagnosis. A P <0.05 was used to indicate statistical significance. Results Half of the 24 patients presented with bleeding requiring blood transfusion on admission. Angiodysplasias were more frequently found in the ascending colon (62%). Valve intervention (surgical or transcatheter) was performed in 70.8% of the patients, and 29.2% remained on drug therapy. News episodes of bleeding occurred in 25% of the cases, and there was no difference between clinical and intervention groups (28.6 vs 23.5%, p = 1.00; respectively). Mortality at 2-year and 5-year was 16% and 25%, with no difference between the groups (log-rank p = 0.185 and 0.737, respectively). Conclusions Patients with Heyde's syndrome had a high rate of bleeding requiring blood transfusion on admission, suggesting that it is a severe disease with high mortality risk. No difference was found between clinical and intervention group regarding the rate of rebleeding and late mortality.


Subject(s)
Humans , Aortic Valve Stenosis/surgery , Aortic Valve Stenosis/diagnostic imaging , Angiodysplasia/complications , Angiodysplasia/therapy , Prospective Studies , Follow-Up Studies , Gastrointestinal Hemorrhage/etiology , Gastrointestinal Hemorrhage/therapy
3.
Arq. bras. cardiol ; 115(4): 680-687, out. 2020. graf
Article in Portuguese | SES-SP, LILACS, SES-SP | ID: biblio-1131356

ABSTRACT

Resumo Fundamento O implante valvar aórtico percutâneo (TAVR, do inglês Transcatheter Aortic Valve Replacement) reduz a mortalidade de pacientes portadores de estenose aórtica grave. O conhecimento da distribuição da pressão e tensão de cisalhamento na parede aórtica pode ajudar na identificação de regiões críticas, onde o processo de remodelamento aórtico pode ocorrer. Neste trabalho é apresentado um estudo de simulação computacional da influência do posicionamento do orifício valvar protético na hemodinâmica na raiz de aorta e segmento ascendente. Objetivos A presente análise apresenta um estudo da variação do padrão de fluxo devido a alterações no ângulo do orifício valvar. Métodos Um modelo tridimensional foi gerado a partir do exame de angiotomografia computadorizada da aorta de um paciente que foi submetido ao procedimento de TAVR. Diferentes vazões de fluxo foram impostas através do orifício valvar. Resultados Pequenas variações no ângulo de inclinação causaram mudanças no padrão de fluxo, com deslocamento na posição dos vórtices, na distribuição de pressão e no local de alta tensão cisalhante na parede aórtica. Conclusão Essas características hemodinâmicas podem ser importantes no processo de remodelamento aórtico e distribuição de tensão, além de auxiliar, em um futuro próximo, a otimização do posicionamento da prótese valvar percutânea. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0)


Abstract Backgroud Transcatheter aortic valve replacement (TAVR) can reduce mortality among patients with aortic stenosis. Knowledge of pressure distribution and shear stress at the aortic wall may help identify critical regions, where aortic remodeling process may occur. Here a numerical simulation study of the influence of positioning of the prosthetic valve orifice on the flow field is presented. Objective The present analysis provides a perspective of great variance on flow behavior due only to angle changes. Methods A 3D model was generated from computed tomography angiography of a patient who had undergone a TAVR. Different mass flow rates were imposed at the inlet valve. Results Small variations of the tilt angle could modify the nature of the flow, displacing the position of the vortices, and altering the prerssure distribution and the location of high wall shear stress. Conclusion These hemodynamic features may be relevant in the aortic remodeling process and distribution of the stress mapping and could help, in the near future, the optimization of the percutaneous prosthesis implantation. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0)


Subject(s)
Humans , Aortic Valve Stenosis/diagnostic imaging , Heart Valve Prosthesis , Heart Valve Prosthesis Implantation , Transcatheter Aortic Valve Replacement/adverse effects , Aorta , Aortic Valve/surgery , Aortic Valve/diagnostic imaging , Aortic Valve Stenosis/surgery , Prosthesis Design , Treatment Outcome , Computed Tomography Angiography , Hemodynamics
4.
Rev. bras. cir. cardiovasc ; 35(3): 307-313, May-June 2020. tab, graf
Article in English | SES-SP, LILACS, SES-SP | ID: biblio-1137277

ABSTRACT

Abstract Objective: To evaluate the clinical and echocardiographic outcomes in aortic valve replacement (AVR) patients with aortic bioprosthesis under oral anticoagulation (OA). Methods: Patients who underwent AVR with bioprosthesiswere prospectively enrolled. They were classified based on postoperative use of OA. Clinical and operative variables were collected. Echocardiographic and clinical follow-ups were performed two years after surgery. The primary outcome evaluated was change in transprosthetic gradient. Secondary outcomes analyzed were change in New York Heart Association (NYHA) class, major bleeding episodes, hospitalization, stroke, and transient ischemic attack. Results: We included 103 patients (61 without OA and 42 with OA). Clinical characteristics were similar among groups, except for younger age (76±6.3 vs. 72.4±8.1 years, P=0.016) and higher prevalence of atrial fibrillation (0% vs. 23.8%, P<0.001) in the OA group. Mean (21.4±10 mmHg vs. 16.8±7.7 mmHg, P=0.037) and maximum (33.4±13.7 mmHg vs. 28.4±10.2 mmHg, P=0.05) transprosthetic gradients were higher in patients without OA. Improvement in NYHA class was more frequent in patients with OA (73% vs. 45.3%, P=0.032). Major bleeding, stroke, and hospitalization were similar among groups. OA was the only independent predictor for improvement of NYHA class after multivariate logistic regression analysis (odds ratio [OR]: 5.9, 95% confidence interval [CI]: 1.2-29.4; P=0.028). Stratification by prosthesis size showed that patients with ≤ 21 mm prosthesis benefited from OA. Conclusion: Early anticoagulation after AVR with bioprosthesis was associated with significant decrease of transprosthesis gradient and improvement in NYHA class. These associations were seen mainly in patients with ≤ 21 mm prosthesis.


Subject(s)
Humans , Aged , Aged, 80 and over , Aortic Valve Stenosis/surgery , Aortic Valve Stenosis/drug therapy , Aortic Valve Stenosis/diagnostic imaging , Bioprosthesis/adverse effects , Heart Valve Prosthesis/adverse effects , Heart Valve Prosthesis Implantation/adverse effects , Aortic Valve/surgery , Aortic Valve/diagnostic imaging , Prosthesis Design , Treatment Outcome , Hemodynamics , Anticoagulants/therapeutic use
5.
Rev. bras. cir. cardiovasc ; 35(3): 241-248, May-June 2020. tab, graf
Article in English | SES-SP, LILACS, SES-SP | ID: biblio-1137266

ABSTRACT

Abstract Objective: To determine the feasibility of aortic valve neocuspidization (AVNeo) with glutaraldehyde-treated autologous pericardium. Methods: One hundred and seventy (170) AVNeo (84 males/86 females) were performed from January 2017 through March 2019 in three centers. All the records were prospectively collected and retrospectively reviewed. Results: Most of the patients were older than 60 years and over 95% were operated for aortic stenosis. Preoperatively, pressure gradients were 69.9±21.3 mmHg for patients with aortic stenosis, and the surgical annular diameter was 21.0±2.0 mm for all patients. Effective orifice area (EOA) and indexed EOA (iEOA) averaged 0.7±0.3 cm2 and 0.4±0.2 cm2/m2 for patients with aortic stenosis before surgery, respectively. There was no conversion to prosthetic aortic valve replacement. Eight patients needed reoperation for bleeding, but no patient needed reoperation due to early infective endocarditis. There were five in-hospital deaths due to noncardiac cause. Compared to preoperative echocardiographic measurements, postoperative peak pressure gradient decreased significantly (-58.7±1.7 mmHg; P<0.001) and reached 11.2±5.6 mmHg, and mean pressure gradient also decreased significantly (-36.8±1.1 mmHg; P<0.001) and reached 6.0±3.5 mmHg. Accordingly, EOA and iEOA increased significantly 2.0 cm2 and 1.0 cm2/m2 (both P<0.001) to reach 2.7±0.6 cm2 and 1.4±0.3 cm2/m2 after surgery, respectively, with minimal significant aortic regurgitation (0.6% > mild). Conclusion: AVNeo is feasible and reproducible with good clinical results. Hemodynamically, AVNeo produces immediate postoperative low-pressure gradients, large EOA, and minimal regurgitation of the aortic valve. Further studies are necessary to evaluate mid- and long-term evolution.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aortic Valve Stenosis/surgery , Aortic Valve Stenosis/diagnostic imaging , Bioprosthesis , Heart Valve Prosthesis , Heart Valve Prosthesis Implantation , Aortic Valve/surgery , Aortic Valve/diagnostic imaging , Pericardium/transplantation , Retrospective Studies , Treatment Outcome , Glutaral
6.
Arq. bras. cardiol ; 114(2): 284-292, Feb. 2020. tab, graf
Article in English | LILACS | ID: biblio-1088875

ABSTRACT

Abstract Background: Diastolic dysfunction, commonly evaluated by echocardiography, is an important early finding in many cardiomyopathies. Cardiac magnetic resonance (CMR) often requires specialized sequences that extends the test time. Recently, feature-tracking imaging has been made available, but still requires expensive software and lacks clinical validation. Objective: To assess diastolic function in patients with aortic valve disease (AVD) and compare it with normal controls by evaluating left ventricular (LV) longitudinal displacement by CMR. Methods: We compared 26 AVD patients with 19 normal controls. Diastolic function was evaluated as LV longitudinal displacement in 4-chamber view cine-CMR images using steady state free precession (SSFP) sequence during the entire cardiac cycle with temporal resolution < 50 ms. The resulting plot of atrioventricular junction (AVJ) position versus time generated variables of AVJ motion. Significance level of p < 0.05 was used. Results: Maximum longitudinal displacement (0.12 vs. 0.17 cm), maximum velocity during early diastole (MVED, 0.6 vs. 1.4s-1), slope of the best-fit line of displacement in diastasis (VDS, 0.22 vs. 0.03s-1), and VDS/MVED ratio (0.35 vs. 0.02) were significantly reduced in AVD patients compared with controls, respectively. Aortic regurgitation showed significantly worse longitudinal LV shortening compared with aortic stenosis. Higher LV mass indicated worse diastolic dysfunction. Conclusions: A simple linear measurement detected significant differences on LV diastolic function between AVD patients and controls. LV mass was the only independent predictor of diastolic dysfunction in these patients. This method can help in the evaluation of diastolic dysfunction, improving cardiomyopathy detection by CMR, without prolonging exam time or depending on expensive software.


Resumo Fundamentos: A disfunção diastólica, comumente avaliada por ecocardiografia, é um importante achado precoce na maioria das cardiomiopatias. A ressonância magnética cardíaca (RMC) frequentemente requer sequências específicas que prolongam o tempo de exame. Recentemente, métodos de imagens com monitoramento de dados (feature-tracking) foram desenvolvidos, mas ainda requerem softwares caros e carecem de validação clínica. Objetivos: Avaliar a função diastólica em pacientes com doença valvar aórtica (DVA) e compará-la a controles normais pela medida do deslocamento longitudinal do ventrículo esquerdo (VE) por RMC. Métodos: Nós comparamos 26 pacientes com DVA com 19 controles normais. A função diastólica foi avaliada como uma medida do deslocamento longitudinal do VE nas imagens de cine-RMC no plano quatro câmaras usando a sequência steady state free precession (SSFP) durante todo o ciclo cardíaco com resolução temporal < 50 ms. O gráfico resultante da posição da junção atrioventricular versus tempo gerou variáveis de movimento da junção atrioventricular. Utilizamos nível de significância de p < 0,005. Resultados: Deslocamento longitudinal máximo (0,12 vs. 0,17 cm), velocidade máxima em início de diástole (0,6 vs. 1,4s-1), velocidade máxima na diástase (0,22 vs. 0,03s-1) e a razão entre a velocidade máxima na diástase e a velocidade máxima em diástole inicial (0,35 vs. 0,02) foram significativamente menores nos pacientes com DVA em comparação aos controles normais, respectivamente. Pacientes com insuficiência aórtica apresentaram medidas de encurtamento longitudinal do VE significativamente piores em comparação aqueles com estenose aórtica. O aumento da massa ventricular esquerda indicou pior disfunção diastólica. Conclusões: Esta simples medida linear detectou diferenças significativas na função diastólica do VE entre pacientes com DVA e controles normais. A massa ventricular esquerda foi o único preditor independente de disfunção diastólica nesses pacientes. Este método pode auxiliar na avaliação da disfunção diastólica, melhorando a detecção de cardiomiopatias por RMC sem prolongar o tempo de exame ou depender de caros softwares.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aortic Valve Insufficiency/physiopathology , Aortic Valve Stenosis/physiopathology , Ventricular Dysfunction, Left/physiopathology , Diastole/physiology , Aortic Valve Insufficiency/diagnostic imaging , Aortic Valve Stenosis/diagnostic imaging , Reference Values , Atrioventricular Node/physiopathology , Atrioventricular Node/diagnostic imaging , Time Factors , Bundle of His/physiopathology , Bundle of His/diagnostic imaging , Case-Control Studies , Linear Models , Retrospective Studies , Ventricular Function, Left/physiology , Ventricular Dysfunction, Left/diagnostic imaging , Statistics, Nonparametric , Magnetic Resonance Imaging, Cine/methods
7.
Arq. bras. cardiol ; 113(6): 1151-1154, Dec. 2019. graf
Article in English | LILACS | ID: biblio-1055066

ABSTRACT

Abstract Transcatheter aortic valve implantation (TAVI) is an established treatment for severe aortic stenosis (AS) in patients with elevated surgical risk. Concomitant coronary artery disease affects 55-70% of patients with severe AS. Percutaneous coronary intervention in patients with TAVI can be challenging. We report a case of acute coronary obstruction immediately following transapical TAVI deployment requiring emergent rotational atherectomy.


Resumo O implante valvar aórtico transcateter (TAVI) é um tratamento estabelecido para estenose aórtica grave (EA) em pacientes com risco cirúrgico elevado. Doença arterial coronariana concomitante afeta 55-70% dos pacientes com EA grave. A intervenção coronária percutânea em pacientes com TAVI pode ser um desafio. Relatamos um caso de obstrução coronariana aguda imediatamente após o implante de TAVI transapical, exigindo aterectomia rotacional emergencial.


Subject(s)
Humans , Male , Aged, 80 and over , Aortic Valve Stenosis/surgery , Percutaneous Coronary Intervention/adverse effects , Transcatheter Aortic Valve Replacement/adverse effects , Aortic Valve/surgery , Aortic Valve/diagnostic imaging , Aortic Valve Stenosis/diagnostic imaging , Tomography, X-Ray Computed , Coronary Angiography , Atherectomy, Coronary/methods
8.
Arq. bras. cardiol ; 110(2): 132-139, Feb. 2018. tab, graf
Article in English | LILACS | ID: biblio-888019

ABSTRACT

Abstract Background: Simplified projected aortic valve area (EOAproj) is a valuable echocardiographic parameter in the evaluation of low flow low gradient aortic stenosis (LFLG AS). Its widespread use in clinical practice is hampered by the laborious process of flow rate (Q) calculation. Objetive: This study proposes a less burdensome, alternative method of Q calculation to be incorporated in the original formula of EOAproj and measures the agreement between the new proposed method of EOAproj calculation and the original one. Methods: Retrospective observational single-institution study that included all consecutive patients with classic LFLG AS that showed a Q variation with dobutamine infusion ≥ -15-% by both calculation methods. Results: Twenty-two consecutive patients with classical LFLG AS who underwent dobutamine stress echocardiography were included. Nine patients showed a Q variation with dobutamine infusion calculated by both classical and alternative methods ≥ -15-% and were selected for further statistical analysis. Using the Bland-Altman method to assess agreement we found a systematic bias of 0,037 cm2 (95% CI 0,004 - 0,066), meaning that on average the new method overestimates the EOAproj in 0,037 cm2 compared to the original method. The 95% limits of agreement are narrow (from -0,04 cm2 to 0,12 cm2), meaning that for 95% of individuals, EOAproj calculated by the new method would be between 0,04 cm2 less to 0,12 cm2 more than the EOAproj calculated by the original equation. Conclusion: The bias and 95% limits of agreement of the new method are narrow and not clinically relevant, supporting the potential interchangeability of the two methods of EOAproj calculation. As the new method requires less additional measurements, it would be easier to implement in clinical practice, promoting an increase in the use of EOAproj.


Resumo Fundamento: A área valvular aórtica projetada simplificada (AEOproj) é um parâmetro ecocardiográfico valioso na avaliação da estenose aórtica de baixo fluxo e baixo gradiente (EA BFBG). Sua utilização na prática clínica é limitada pelo trabalhoso processo de cálculo da taxa de fluxo (Q). Objetivos: Este estudo propõe um método alternativo, menos complexo, para o cálculo da Q para ser incorporado na fórmula original da AEOproj, e mede a concordância entre o novo método proposto para o cálculo da AEOproj em comparação ao método original. Métodos: Estudo retrospectivo, observacional, unicêntrico que incluiu todos os pacientes com AE BFBG clássica com variação da Q com infusão de dobutamina ≥ -15-% por ambos os métodos. Resultados: Foram incluídos 22 pacientes consecutivos com AE BFBG clássico, que se submeteram à ecocardiografia sob estresse com dobutamina. Nove pacientes apresentaram uma variação da Q com infusão de dobutamina calculada tanto pelo método clássico como pelo método alternativo ≥ -15-%, e foram selecionados para análise estatística. Utilizando método Bland-Altman para avaliar a concordância, encontramos um viés sistemático de 0,037 cm2 (IC 95% 0,004 - 0,066), o que significa que, em média, o novo método superestima a AEOproj em 0m037 cm2 em comparação ao método original. Os limites de concordância de 95% são estreitos (de -0,04 cm2 a 0,12 cm2), o que significa que para 95% dos indivídios, a AEOproj calculada pelo novo método estaria entre 0,04 cm2 menos a 0,12 cm2 mais que a AEOproj calculada pela equação original. Conclusão: O viés e os limites de 95% de concordância do novo método são estreitos e não são clinicamente relevantes, o que corrobora a intercambialidade dos dois métodos de cálculo da AEOproj. Uma vez que o novo método requer menos medidas, seria mais fácil de ser implementado na prática clínica, promovendo um aumento na utilização da AEOproj.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Aortic Valve/diagnostic imaging , Aortic Valve Stenosis/diagnostic imaging , Echocardiography, Stress/methods , Aortic Valve/physiopathology , Severity of Illness Index , Blood Flow Velocity , Infusions, Intravenous , Echocardiography, Doppler/methods , Retrospective Studies , Ventricular Function, Left , Dobutamine/administration & dosage , Adrenergic beta-1 Receptor Agonists/administration & dosage , Hemodynamics
11.
Rev. chil. cardiol ; 36(2): 97-105, 2017. ilus, tab, graf
Article in Spanish | LILACS | ID: biblio-899573

ABSTRACT

Introducción: La estenosis aórtica es frecuente en países desarrollados, cuando es severa (EAS) y sintomática se recomienda reemplazo valvular. Su diagnóstico ecocardiográfico se realiza con cualquiera de; área valvular aórtica (AVA) <1.0 cm², gradiente medio (GM) >40 mmHg, velocidad máxima >4 m/s. Habitualmente existe concordancia entre estos criterios, pero diversas razones generan discordancia hasta en un 40%, principalmente entre área y gradiente (DAG), causando incertidumbre diagnóstica en presencia de fracción de eyección preservada del ventrículo izquierdo (FEp) (FEVI >50%). Objetivos: Caracterizar pacientes con EAS en la red UC. Establecer prevalencia y factores asociados a DAG en pacientes con EAS y FEp. Métodos: Estudio de corte transversal, incluyó todos los pacientes con AVA<1.0 cm2 durante 17.5 años en la red UC. Se registraron variables biodemográficas y eco-cardiográficas. Los pacientes con EAS y FEp se subdivi-dieron en 2 grupos según GM, bajo (<40 mmHg) y alto (>40mmHg), se utilizó t-student y Chi cuadrado. Resultados: 1281 pacientes cumplieron criterio de AVA<1.0 cm2. Edad 71.8±13 años, mujeres 51.4%, hombres el 48.6%. FEVI 68.71 ± 14.62%, FEp 89,2%, Características grupo GM Bajo: Edad 81.66 ± 6.56 años, Mujeres 56.3%, fibrilación auricular (FA) 14.1%. Grupo GM Alto. 68.08 ± 13.21 años, mujeres 47.6%, FA 8%. Presencia de DAG 42.5%. Factores asociados a bajo gradiente con FEp fueron: edad avanzada (>70 años), mujer y fibrilación auricular. Conclusiones: La EAS en nuestro medio se observa en personas mayores con FEp. La presencia de DAG es frecuente y el principal factor asociado en presencia de FEp es la FA.


Introduction: Aortic stenosis (AS) is the most prevalent valvular heart disease in developed countries. Symptomatic severe AS requires surgical intervention, and its echocardiographic criteria encompass: Aortic valve area (AVA) < 1.0 cm2, aortic mean gradient (MG) > 40 mmHg, peak aortic jet velocity > 4 m/s. Usually there is agreement among these criteria, but several reasons can cause up to 40% discordant results, mainly between AVA an MG, casting doubt about severity in the setting of preserved left ventricular ejection fraction (pLVEF). Objectives: Characterize patients with severe AS. Assess prevalence and factors related to AG discordance (AGD) in patients with pLVEF. Methods: Cross-sectional study, that included all patients with an AVA <1.0 cm2 during the last 17.5 years in UC health network. Bio-demographic and echocardiographic variables were registered. Patients with severe AS and pLVEF where allocated in 2 subgroups according to the MG as low (<40 mmHg) and high (>40 mmHg), 2 sides t-student and chi-squared test were performed. Results: 1281 patients fulfill criteria of AVA<1.0 cm2. Age 71.8±13 years, women 51.4%, male 48.6%, LVEF 68.71 ± 14.62%. pLVEF 89.2%. Low MG group: Age 81.66 ± 6.56 y, women 56.3%, atrial fibrillation (AF) 14.1%. High MG group: Age 68.08 ± 13.21 y, women 47.6%, AF 8%. AGD prevalence was 42.5%. Factors related to low MG with pLVEF were; advance age (>70 y), women and AF. Conclusions: Severe AS occurs mainly in advance age patients with pLVEF. AGD is frequent and the foremost related factor is AF.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aortic Valve Stenosis/physiopathology , Stroke Volume/physiology , Aortic Valve Stenosis/diagnostic imaging , Echocardiography, Doppler , Chi-Square Distribution , Cross-Sectional Studies , Ventricular Function, Left/physiology , Sex Distribution , Ventricular Remodeling/physiology
12.
Rev. chil. obstet. ginecol ; 81(3): 229-233, jun. 2016. ilus
Article in Spanish | LILACS | ID: lil-788914

ABSTRACT

Las cardiopatías son las malformaciones congénitas más frecuentes del desarrollo prenatal, en las que se produce un defecto en la arquitectura normal del corazón fetal interfiriendo en su buen funcionamiento en la vida postnatal. La proporción entre las diferentes cardiopatías varía mucho, sin embargo el Síndrome de Corazón Izquierdo Hipoplásico representa el 2-3% del total de cardiopatías congénitas constituyendo la forma más severa de lesiones obstructivas del corazón izquierdo y la de peor pronóstico. Su diagnóstico en etapas precoces de la gestación es hoy un reto para el obstetra, ya que su carácter evolutivo dificulta este hecho, no siendo en ocasiones, hasta etapas avanzadas de la gestación cuando se produce la alteración anatómica y la subsiguiente expresión ecográfica. Es en este punto donde se debe hacer hincapié, intentando aumentar el número de casos detectados precozmente, lo cual permitiría un adecuado aseso-ramiento familiar y la toma de decisiones oportuna. En los últimos años la introducción de terapias en patología cardíaca fetal, ha despertado un gran interés por tratar de modificar la evolución de esta enfermedad, siendo la valvuloplastía con balón aórtico la técnica de elección en pacientes seleccionados.


Congenital heart defects are the most frecuently congenital malformations in the prenatal development and consist of defect in the normal architecture of the fetal heart which interfering with its proper functioning. The proportion between the different heart disease varies widely, however Hypoplastic Left Heart Syndrome (HLHS) represent 2-3% of all congenital heart diseases and constitute the most severe obstructive lesions of the left heart and worse prognosis. The quickly diagnosis in early stages of the disease is an obstetrician challenge, however, it s evolutional feature hinders this proposal even in advanced stages of pregnancy when the anatomical alteration and subsequent ultrasound expression can be occur. At this point that should be emphasized to try increasing the number of cases detected early, which would allow a proper family counseling and timely decision. Recent years the introduction of therapies on fetal cardiac pathology, has aroused great interest in trying to change the course of the disease and the fetal aortic valvuloplasty with aortic balloon would be the choice technique in selected patients.


Subject(s)
Humans , Female , Pregnancy , Adult , Ultrasonography, Prenatal , Hypoplastic Left Heart Syndrome/diagnostic imaging , Aortic Valve Stenosis/etiology , Aortic Valve Stenosis/diagnostic imaging , Hypoplastic Left Heart Syndrome/complications , Early Diagnosis , Heart Defects, Congenital
13.
Rev. chil. cardiol ; 34(1): 28-35, abr. 2015. ilus, tab, graf
Article in Spanish | LILACS | ID: lil-749425

ABSTRACT

Introducción: Para el reemplazo de válvula aórtica con catéteres (TAVR) es fundamental la adecuada medición del anillo aórtico para elegir el tamaño adecuado de la prótesis y evitar complicaciones graves como la ruptura del anillo aórtico y la insuficiencia paravalvular (IAP). La tomografía computada cardíaca (TC) es el estándar de oro en la medición del anillo aórtico, pero la ecocardiografía transesofágica 3D (ETE3D) parece ser una alternativa atractiva. Objetivo: Evaluar la correlación entre las mediciones del anillo aórtico obtenidas por ETE3D y las encontradas en la TC. Los resultados obtenidos se evaluaron en términos de la prótesis elegida y la presencia de insuficiencia aórtica post TAVR. Métodos: Se realizaron de manera retrospectiva y ciega, las mediciones del anillo aórtico por TC y ETE3D en 18 pacientes consecutivos, edad promedio 82 ± 7,06 años, sometidos a TAVR usando prótesis Sapien XT (Edwards Lifescience). Se comparó el diámetro máximo, diámetro mínimo, diámetro medio, área y perímetro del anillo. Resultados: La ETE3D subvaloró el tamaño del anillo aórtico, pero demostró tener una buena correlación con los diferentes parámetros de la TC, con mejor comportamiento para el perímetro del anillo. ETE3D y TC coincidieron en la elección de la prótesis en 17 pacientes y no hubo IAP de relevancia. Conclusión: La ETE3D tiene buena correlación comparada contra la TC en la valoración del anillo aórtico. La ETE3D parece una atractiva alternativa a la TC para medición del anillo especialmente en casos complejos o cuando la disponibilidad y acceso a la TC puede estar limitada.


In TAVR, the precise measuring of the aortic annulus is essential to determine the size of the prosthesis and to avoid complications like rupture of the annulus of aortic insufficiency. Computed tomography (CT) is the gold standard to achieve these goals. 3-D trans-esophageal echocardiography (3-D TEE) to be a useful alternative method. Aim: to evaluate the correlation of aortic annulus measurements obtained with 3-dTE and CT in the determination of annulus measurements before TAVR. Prosthesis size and presence of aortic insufficiency were related to these measurements. Methods: In a retrospective blinded protocol the measurements of the aortic annulus obtained with CT or 3D-TEE were correlated in 18 consecutive patients (mean age 82 ± 7.1) submitted to TAVR with a Sapien XT (Edwards Lifescience) prosthesis. Maximal, minimal and mean diameters as well as area and annular circumference were evaluated. Results: Compared to CT, 3D-TEE under estimated de size of the aortic annulus but correlated well with other measurements of CT, especially with the annular circumference. Measurements from both methods agreed in the determination of the prosthesis size in 17 of 18 patients. No significant per prosthetic aortic insufficiency was observed in any case. Conclusion: 3DTEE correlates well with CT in evaluating the different parameters of the aortic annulus and is a good alternative to CT in complex cases and when CT is not readily available.


Subject(s)
Humans , Aortic Valve/diagnostic imaging , Aortic Valve Stenosis/diagnostic imaging , Echocardiography, Transesophageal/methods , Echocardiography, Three-Dimensional/methods , Multidetector Computed Tomography/methods , Transcatheter Aortic Valve Replacement/methods , Aortic Valve Stenosis/therapy , Prosthesis Design , Preoperative Care , Retrospective Studies
14.
Rev. Méd. Clín. Condes ; 26(2): 217-222, mar. 2015.
Article in Spanish | LILACS | ID: biblio-1128821

ABSTRACT

Estenosis aórtica (EA) es la enfermedad valvular más común referida para tratamiento quirúrgico. La ecocardiografía es el método de referencia para la evaluación de la severidad. La actual Guía Norteamericana define EA severa como un área valvular derivada por ecuación de continuidad (AVA) 1 cm2, área valvular indexada (Avaí) 0,6 cm2 / m2, gradiente medio de (MG) 40mmHg, y velocidad máxima (Vmax)> 4 m / s. La valoración ecocardiográfica de la EA es compleja, ya que depende de unas pocas mediciones críticas que son técnicamente demandantes, sujetas a errores y dependientes de metodologías de adquisición variable a través de las instituciones. Debe buscarse sistematización y estandarización de los enfoques metodológicos para las mediciones fundamentales de la válvula aórtica. Integrar la ecocardiografía con nuevas herramientas, como el score de calcio por CT y la RM tiene el potencial de hacer una plataforma más amplia para individualizar la severidad de la EA.


Aortic stenosis (AS) is the most common valvular disease referred for surgical treatment. Echocardiography is the state-of-the-art method of AS severity evaluation. Current US guidelines define severe AS as a continuity equation-derived valve area (AVA) 1 cm2, indexed valve area (AVAi) 0.6 cm2/m2, mean gradient (MG) 40mmHg, and peak velocity (Vmax) 4 m/s. Echocardiographic AS grading is complex since it relies on a few critical measurements that are technically demanding, subject to error and of variable acquisition methodology across institutions. Systematisationandstandardisationofmethodologicapproaches for fundamental echocardiographic aortic valve measurements must be sought. Integration of echocardiography with emerging independent tools such as CT valvular-calcium-load assessment and MRI has the potential of rendering a more comprehensive platform from which to individualise AS severity grading.


Subject(s)
Humans , Aortic Valve Stenosis/diagnostic imaging , Aortic Valve Stenosis/pathology , Severity of Illness Index , Echocardiography/methods , Tomography, X-Ray Computed , Imaging, Three-Dimensional
15.
Ann Card Anaesth ; 2009 Jul; 12(2): 173-III
Article in English | IMSEAR | ID: sea-135183

ABSTRACT

Trans-esophageal echocardiography (TEE) is routinely used in valvular surgery in most institutions. The popularity of TEE stems from the fact that it can supplement or confirm information gained from other methods of evaluation or make completely independant diagnoses. Quantitative and qualitative assessment permits informed decisions regarding surgical intervention, type of intervention, correction of inadequate surgical repair and re-operation for complications. This review summarizes the various methods for quantification of aortic regurgitation and stenosis on TEE. The application of Doppler echo (pulsed wave, continuous wave and color) with two-dimensional echo allows the complete evaluation of AV lesions.


Subject(s)
Algorithms , Aortic Valve/surgery , Aortic Valve/diagnostic imaging , Aortic Valve Insufficiency/surgery , Aortic Valve Insufficiency/diagnostic imaging , Aortic Valve Stenosis/surgery , Aortic Valve Stenosis/diagnostic imaging , Echocardiography , Echocardiography, Doppler , Echocardiography, Transesophageal , Endocardial Cushion Defects/surgery , Endocardial Cushion Defects/diagnostic imaging , Heart Valve Prosthesis Implantation , Hemodynamics/physiology , Humans , Pulmonary Artery/surgery , Pulmonary Veins/abnormalities , Pulmonary Veins/diagnostic imaging
17.
Indian Heart J ; 1990 May-Jun; 42(3): 195-7
Article in English | IMSEAR | ID: sea-4635

ABSTRACT

Two dimensional echocardiographic measurements of the size of aortic and pulmonary valve annulus were made in 60 patients before balloon valvoplasty and compared to the angiographic measurements. Aortic valve annulus was measured in 34 patients (26 with valvar aortic stenosis and 8 with discrete subaortic stenosis) in the parasternal long axis or apical 5-chamber views. The pulmonary valve annulus was measured in 26 patients with valvar pulmonary stenosis (PS) in the parasternal short axis view of the right ventricular outflow view. The visualization of the annulus was good in all except 2 patients with valvar PS. Angiographic measurements of the aortic and pulmonary valve annulus were made in aortic root and right ventricular angiograms respectively, taken in both right and left anterior oblique views. There was an excellent correlation between the measurements of the annulus size by the two techniques (r value for pulmonary valve 0.91; for aortic valve 0.96; over all 0.94). Echocardiography can accurately measure valve annulus size and help in choosing balloon dilatation catheter of appropriate size before the valvoplasty procedure.


Subject(s)
Adolescent , Adult , Aortic Valve/diagnostic imaging , Aortic Valve Stenosis/diagnostic imaging , Child , Child, Preschool , Echocardiography , Female , Humans , Male , Middle Aged , Pulmonary Valve/diagnostic imaging , Pulmonary Valve Stenosis/diagnostic imaging
SELECTION OF CITATIONS
SEARCH DETAIL