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1.
In. Verga, Federico; Burghi, Gastón. Encares de paciente crítico. Montevideo, Oficina del Libro FEFMUR, 2020. p.459-471, tab, ilus.
Monography in Spanish | LILACS, BNUY, UY-BNMED | ID: biblio-1342677
2.
Adv Rheumatol ; 60: 11, 2020. tab, graf
Article in English | LILACS | ID: biblio-1088644

ABSTRACT

Abstract Background: The current diagnostic cornerstone for septic arthritis contains gram stains, bacterial culture, and cell count with a differential of aspirated synovial fluid. Recently, a synovial leukocyte esterase (LE) test has been used for diagnosing septic arthritis. Since this test measures the esterase activity of leukocytes, there is always a dilemma for using this test in patients with inflammatory arthritis. Methods: We collected the synovial fluid specimens as part of the general diagnostic protocol for patients suspected of Juvenile Idiopathic Arthritis (JIA) or Septic Arthritis (SA). Each group included 34 patients. We compared the result of the synovial LE test with the result of the culture of each patient. Results: The mean ages of patients were 64.14 ± 31.27 and 50.88 ± 23.19 months in the JIA group and septic arthritis group, respectively. The LE test results were positive in 30 specimens, trace in 3 and negative in one in the first-time test and were positive in 31 specimens and trace in 3 in the second-time test, while it was negative in all patients with JIA. Hence, the sensitivity of the synovial LE test was 80.8%, the specificity, PPV, and NPV were 78.6, 70.0, 86.8% respectively based on a positive culture. Conclusion: The leukocyte esterase strip test can be used as a rapid, bedside method for diagnosing or excluding bacterial infections in different body fluids. The synovial LE test can be used as an accurate test to rapidly rule in or out an acute articular bacterial infection, even in patients with concurrent inflammatory arthritis.(AU)


Subject(s)
Humans , Arthritis, Rheumatoid/diagnosis , Synovial Fluid/chemistry , Arthritis, Infectious/diagnosis , Leukocyte Count
3.
Rev. Soc. Bras. Med. Trop ; 52: e20180253, 2019.
Article in English | LILACS | ID: biblio-977118

ABSTRACT

Abstract An eleven-year-old boy presented with fever and hip pain, with limited mobility of the right side of the hip. Computed tomography scan revealed an increased volume of the right coxo-femoral joint, requiring surgical drainage of purulent secretion, from which Salmonella enterica was isolated. After four weeks of treatment with third-generation cephalosporin, he was discharged with a favorable evolution. Invasive disease caused by Salmonella spp represents a small proportion of salmonellosis cases, although it is responsible for greater rates of hospitalization, morbidity and mortality. Children under 5 years, elders over 60 years and immunodeficient patients have greater risk for invasive salmonellosis.


Subject(s)
Humans , Child , Salmonella Infections/microbiology , Arthritis, Infectious/microbiology , Salmonella enterica/isolation & purification , Salmonella Infections/diagnosis , Salmonella Infections/drug therapy , Arthritis, Infectious/diagnosis , Arthritis, Infectious/drug therapy
4.
Rev. Soc. Bras. Med. Trop ; 51(4): 554-556, July-Aug. 2018. tab, graf
Article in English | LILACS | ID: biblio-957447

ABSTRACT

Abstract Staphylococcus lugdunensis is a rare virulent coagulase-negative staphylococcus (CoNS) that behaves similarly to Staphylococcus aureus in causing deep abscesses, skin and soft tissue infections, and central nervous system infections. Additionally, there can be certain blood stream infections including sepsis, septic shock, toxic shock syndrome, and endocarditis complicated by embolic events. Reports of septic arthritis of a native joint associated with this organism have been infrequent, justifying the presentation and discussion of this case.


Subject(s)
Humans , Male , Staphylococcal Infections/microbiology , Arthritis, Infectious/microbiology , Staphylococcus lugdunensis/isolation & purification , Hip Joint/microbiology , Staphylococcal Infections/diagnosis , Staphylococcal Infections/drug therapy , Arthritis, Infectious/diagnosis , Arthritis, Infectious/drug therapy , Tomography, X-Ray Computed , Middle Aged , Anti-Bacterial Agents/therapeutic use , Nafcillin/therapeutic use
6.
Niger. j. surg. (Online) ; 23(1): 26-32, 2017. ilus
Article in English | AIM | ID: biblio-1267510

ABSTRACT

Background: Childhood pyogenic septic arthritis and its associated musculoskeletal morbidity is an important health concern in developing countries. Its pattern of presentation that varies from and within subregions has implications on the early recognition, treatment, and outcome. The aim of this study was to determine the pattern and outcome of childhood septic arthritis in our environment. Materials and Methods: This was a retrospective study of all the children seen with pyogenic septic arthritis in Federal Teaching Hospital Abakaliki between January 2005 and December 2015. Results: Childhood septic arthritis accounted for 44 (83%) of the 53 patients seen with pyogenic septic arthritis. Female to male ratio was 1:1.75 and the mean age was 5.7 ± 0.73 years. Eight patients (18.2%) had polyarticular involvements. The right shoulder was significantly more involved than the left and the left hip more than right. Overall, there was a preponderance of onset of symptoms in the dry season. Children from the rural areas accounted for 85.7% of those with the onset of symptom in rainy season. Delayed presentation >6 days (in 68.2% of patients) was related to age (P < 0.042), and health seeking behavior (P < 0.036). Staphylococcus aureus was the commonest causative organism. Seventy-seven percent (77%) underwent open arthrotomy. Anemia, septic shock, and joint stiffness were three top complications observed. Mortality rate was 2.3%, and cause of death was overwhelming sepsis. Conclusion: In our setting, pyogenic septic arthritis is predominantly a childhood health problem and children under 5 years of age are the most vulnerable. Delayed presentation, an important factor in morbidity and mortality associated with septic arthritis was common among the patients, calls for a public enlightenment program on the importance of early presentation


Subject(s)
Arthritis, Infectious/diagnosis , Arthritis, Infectious/physiopathology , Arthritis, Infectious/therapy , Child , Hospitals, Teaching , Nigeria , Staphylococcal Infections
7.
Rev. Soc. Bras. Med. Trop ; 49(6): 793-795, Dec. 2016. graf
Article in English | LILACS | ID: biblio-829662

ABSTRACT

Abstract Candida arthritis is an unusual manifestation that usually affects the knees. A 35-year-old man presented with a 2-month history of pain and swelling in the right knee. Swelling persisted after anti-inflammatory treatment. Peripheric spondyloarthritis was considered, but methotrexate, sulfasalazine, and methylprednisolone did not reduce the swelling. Direct examination of synovial fluid and a culture were positive for Candida albicans. Intravenous and intra-articular amphotericin-B were administered. The arthritis regressed and a culture and direct staining showed negative results. Candida arthritis should be considered in patients with arthritis that is resistant to treatment and prolonged, even if risk factors are absent.


Subject(s)
Humans , Male , Adult , Candida albicans/isolation & purification , Candidiasis/complications , Arthritis, Infectious/microbiology , Ankle Joint/microbiology , Candidiasis/diagnosis , Arthritis, Infectious/diagnosis , Spondylarthritis/diagnosis , Diagnosis, Differential
8.
Braz. j. infect. dis ; 19(5): 546-548, graf
Article in English | LILACS | ID: lil-764497

ABSTRACT

ABSTRACTFungal arthritis is a rare complication of arthroscopic surgeries, but its possibility should always be considered due its deleterious effects on any joint. Infection caused by the fungus Histoplasma capsulatum is the most common cause of respiratory tract infections by fungi, meanwhile histoplasmosis arthritis is more rare than all other fungal infections. However, their atypical forms of arthritis and the importance of early diagnosis and treatment cannot be over-emphasized. Herein we report a case of knee monoarthritis in an immunocompetent patient with histoplasmosis arthritis following an arthroscopic meniscetomy, diagnosed by synovial biopsy and culture performed during a second arthroscopic procedure. The joint was debrided in this second intervention and the patient received itraconazole initially and fluconazole latter on. The arthritis subsided after 10 months of treatment.


Subject(s)
Aged , Female , Humans , Arthritis, Infectious/diagnosis , Arthroscopy/adverse effects , Histoplasma/isolation & purification , Histoplasmosis/diagnosis , Knee Joint/microbiology , Antifungal Agents/therapeutic use , Arthritis, Infectious/drug therapy , Arthritis, Infectious/etiology , Fluconazole/therapeutic use , Histoplasmosis/drug therapy , Histoplasmosis/etiology , Itraconazole/therapeutic use
9.
Rev. méd. Chile ; 143(6): 805-808, jun. 2015. ilus
Article in Spanish | LILACS | ID: lil-753522

ABSTRACT

Septic arthritis of the temporomandibular joint (TMJ) is an uncommon condition, caused by hematic bacterial migration or direct migration of other head and neck infections. We report a 41 year old female who presented a right temporomandibular joint involvement, with bone destruction of the mandibular condyle and an infectious process spreading to the temporal space, following a necrotizing medial and external otitis with associated mastoiditis. A septic arthritis of the TMJ by continuity was diagnosed and treated with antimicrobials, TMJ arthrocentesis and occlusal stabilization, with a positive evolution. However, the patient remains in control due a secondary TMJ osteoarthritis caused by the septic arthritis.


Subject(s)
Adult , Female , Humans , Arthritis, Infectious/complications , Temporomandibular Joint Disorders/etiology , Anti-Bacterial Agents/therapeutic use , Arthritis, Infectious/diagnosis , Arthritis, Infectious/drug therapy , Mastoiditis/etiology , Tomography, X-Ray Computed , Tooth Extraction , Temporomandibular Joint Disorders/surgery
10.
Acta ortop. mex ; 29(2): 123-126, mar.-abr. 2015. ilus, tab
Article in Spanish | LILACS | ID: lil-771826

ABSTRACT

La monoartritis es un reto diagnóstico para el clínico, ya que es extensa la lista de patologías asociadas. En pacientes con diagnóstico establecido de enfermedad articular inflamatoria, se acepta que la monoartritis corresponde a la exacerbación de la enfermedad de base; sin embargo, ignorar el abordaje sistematizado de las monoartritis puede generar omisiones e implicaciones diagnósticas erróneas. En este reporte se analiza el abordaje de un caso de artritis seudoséptica, simulando un ataque agudo de artritis por urato monosódico recurrente en un paciente con retención de cuerpo extraño intraarticular.


Monoarthritis is a diagnostic challenge for the clinician, as the list of associated conditions is quite long. It is accepted that in patients with a diagnosis of inflammatory joint disease monoarthritis represents exacerbation of the underlying disease. However, ignoring the systematized approach to monoarthritides may lead to omissions and mistaken diagnostic implications. This report describes the approach to a case of pseudoseptic arthritis that mimicked an acute episode of recurrent arthritis due to monosodium urate in a patient with retention of an intraarticular foreign body.


Subject(s)
Adult , Humans , Male , Arthritis, Infectious/diagnosis , Foreign Bodies/diagnosis , Gout/pathology , Synovitis/diagnosis , Arthritis, Infectious/pathology , Foreign Bodies/pathology , Synovitis/pathology , Uric Acid/metabolism
12.
Article in English | WPRIM | ID: wpr-119048

ABSTRACT

BACKGROUND: The authors conducted the present study to identify clinical and radiological prognostic factors in infants and neonates with septic arthritis of the hip. METHODS: The authors retrospectively reviewed the records of 31 patients with septic arthritis of the hip. All of the patients were younger than 18 months old. Follow-up periods ranged from 5 to 17 years. The following potential variables for predicting the prognosis were included in the assessment: gender, age, underlying diseases, duration of symptoms, changes of hip joint in X-ray, concomitant osteomyelitis, elevation of erythrocyte sedimentation rate and C-reactive protein, sepsis, pus drainage, synovial fluid culture, and infecting organisms. Clinical and radiological prognoses were analyzed at the final follow-up. RESULTS: Univariate analysis demonstrated that radiological prognoses were poorer in patients who had underlying diseases, a longer duration of symptoms, and pus drainage. However, on multivariate analysis, only the variable-duration of symptoms-was found to be statistically related with a poor radiological prognosis. CONCLUSIONS: Although poor prognosis for patients with several underlying diseases and radiological changes has already been established, a favorable outcome might be expected with prompt surgical drainage and appropriate antibiotics.


Subject(s)
Arthritis, Infectious/diagnosis , Female , Follow-Up Studies , Hip Joint , Humans , Infant , Infant, Newborn , Male , Prognosis , Retrospective Studies
13.
Article in English | WPRIM | ID: wpr-119046

ABSTRACT

Acromioclavicular (AC) and sternoclavicular (SC) septic arthritis with contiguous pyomyositis are rare, especially in immunocompetent individuals. We report a case of septic AC joint with pyomyositis of the deltoid and supraspinatus muscles and a separate case with septic SC joint with pyomysitis of the sternocleidomastoid muscle. Both patients had similar presentations of infections with Staphylococcus aureus and were successfully treated with surgical incision and drainage followed by prolonged antibiotic therapy.


Subject(s)
Acromioclavicular Joint/microbiology , Adult , Anti-Bacterial Agents/administration & dosage , Arthritis, Infectious/diagnosis , Female , Humans , Magnetic Resonance Imaging , Pyomyositis/diagnosis , Staphylococcal Infections/complications , Staphylococcus aureus , Sternoclavicular Joint/microbiology
14.
Article in English | WPRIM | ID: wpr-146131

ABSTRACT

Septic arthritis and gout are major diseases that should be suspected in patients with acute monoarthritis. These two diseases are clinically similar and often indistinguishable without the help of synovial fluid analysis. Recently, a novel diagnostic rule for gout without synovial fluid analysis was developed and showed relevant performances. This study aimed to determine whether this diagnostic rule could perform well in distinguishing gout from septic arthritis. The diagnostic rule comprises 7 clinical and laboratory variables, each of which is given a specified score. The probability of gout is classified into 3 groups according to the sum of the scores: high (> or = 8), intermediate (> 4 to < 8) and low probability (< or = 4). In this retrospective study, we applied this diagnostic rule to 136 patients who presented as acute monoarthritis and were subsequently diagnosed as acute gout (n = 82) and septic arthritis (n = 54) based on synovial fluid analysis. The mean sum of scores of acute gout patients was significantly higher than that of those with septic arthritis (8.6 +/- 0.2 vs. 3.6 +/- 0.32, P < 0.001). Patients with acute gout had significantly more 'high', and less 'low' probabilities compared to those with septic arthritis (Eta[eta]: 0.776). The prevalence of acute gouty arthritis, as confirmed by the presence of monosodium crystal, was 95.5% (61/64), 57.5% (19/33), and 5.1% (2/39) in high, intermediate and low probability group, respectively. The recently introduced diagnostic rule properly discriminates acute gout from septic arthritis. It may help physicians diagnose gout in cases difficult to be differentiated from septic arthritis.


Subject(s)
Acute Disease , Algorithms , Arthritis, Gouty/diagnosis , Arthritis, Infectious/diagnosis , Data Interpretation, Statistical , Decision Support Techniques , Diagnosis, Computer-Assisted/methods , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Reproducibility of Results , Sensitivity and Specificity
15.
Rev. chil. infectol ; 31(4): 435-443, ago. 2014. tab
Article in Spanish | LILACS | ID: lil-724814

ABSTRACT

Background: Septic arthritis is an infrequent condition of prolonged morbidity and there is no previous publications in Chile that allow orientate therapy. Aim: To characterize a group of adult patients with septic arthritis confirmed by culture. Material and Methods: Descriptive study of a case series. Results: From 2003 to august 2013, 24 patients with 25 events of septic arthritis were identified in a general hospital. Mean age was 68.3 years old (range 24-94). Predisposing conditions were harbored by 91.7%. Predominant clinical manifestations were pain (92%) and impaired joint movement (95.7%). Fever was present in 64%, hypotension in 28% of events, and C-reactive protein > 100 mg/L in 90.6%. Gram positive cocci were the most frequently isolated microorganisms (81.5%), predominating S. aureus (48.1%), and with 4 isolates methicillin resistant isolates (26.7%). Resistant isolates trend to be associated with previous surgery (p = 0.055) and all cases caused by non-fermentative Gram negative bacilli had recent hospitalization or surgery, a feature that did not reach a significant difference. Nine events were associated to bacteremia (36%). Outcome analysis indicated 32% of events with full recovery, 28% with a favorable evolution, 20% with therapy failure and 16.7% patients that died. A total of 24% of the series remained with significant sequels. Conclusions: Septic arthritis is an infrequent disease that affects in most cases patients with predisposing conditions. Associated symptoms include pain and impaired joint movement, sometimes fever, hypotension, positive blood cultures and frequently a C-reactive protein > 100 mg/L. Predominant agents are Gram positive cocci, specially S. aureus, including methicillin resistant isolates. Case-fatality ratio, treatment failure and sequels are important.


Antecedentes: Los cuadros de artritis séptica son esporádicos pero de elevada morbilidad y no hay publicaciones en Chile que permitan orientar el tratamiento de ellos. Objetivos: Caracterizar un grupo de pacientes con cuadros de artritis séptica confirmados microbiológicamente. Pacientes y Métodos: Serie de casos. Resultados: Un total de 24 pacientes con 25 eventos de artritis séptica fue identificado entre el 2003 y agosto de 2013. La edad promedio fue de 68,3 años (24-94) y 91,7% tuvo condiciones que predisponen. Las manifestaciones clínicas dominantes fueron dolor (92%) e impotencia funcional (95,7%), 64% presentó fiebre y 28% tuvo hipotensión arterial. Un 90,6% tuvo PCR > 100 mg/L. Las cocáceas grampositivas fueron los microorganismos más frecuentes (81,5%), predominando Staphylococcus aureus (48,1%) y cuatro cepas estafilocóccicas presentaron resistencia a cloxacilina (26,7%). Las cepas resistentes tendieron a estar asociadas a pacientes con cirugía articular previa (p: 0,055) y todos los casos asociados a bacilos gramnegativos no fermentadores tenían antecedentes de hospitalización reciente o cirugía articular previa. Nueve eventos (36%) se asociaron a bacteriemia. Un 32% de los pacientes tuvo curación, 28% un curso favorable, 20% fracaso y 16,7% falleció. Un 24% quedó con secuelas. Conclusiones: Los cuadros de artritis séptica son infrecuentes, afectan en su mayor parte a pacientes con factores que predisponen, se presentan con dolor e impotencia funcional, a veces fiebre, hipotensión arterial o bacteriemia y generalmente con PCR > 100 mg/L. Se asocian a cocáceas grampositivas, especialmente S. aureus, incluyendo aislados resistentes a cloxacilina. La letalidad, fracaso del tratamiento y secuelas no son despreciables.


Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Arthritis, Infectious , Anti-Bacterial Agents/therapeutic use , Arthritis, Infectious/diagnosis , Arthritis, Infectious/drug therapy , Arthritis, Infectious/microbiology , Chile , Hospitals, General , Prognosis , Retrospective Studies
16.
Article in English | WPRIM | ID: wpr-165347

ABSTRACT

Direct plating of synovial fluid (SF) on agar-based media often fails to identify pathogens in septic arthritis (SA). We developed a PCR assay for the simultaneous detection of Kingella kingae and Staphylococcus aureus from SF to evaluate molecular detection in SF and to estimate the incidence of K. kingae in SA in North America. The assay was based on detection of the cpn60 gene of K. kingae and the spa gene of S. aureus in multiplex real-time PCR. K. kingae was identified in 50% of patients between 0 and 5 yr of age (n=6) but not in any patients >18 yr old (n=105). Direct plating of SF on agar-based media failed to detect K. kingae in all samples. The PCR assay was inferior to the culture-based method for S. aureus, detecting only 50% of culture-positive cases. Our findings suggest that K. kingae is a common pathogen in pediatric SA in North America, in agreement with previous reports from Europe. PCR-based assays for the detection of K. kingae may be considered in children with SA, especially in those with a high degree of clinical suspicion.


Subject(s)
Adult , Arthritis, Infectious/diagnosis , Bacterial Proteins/genetics , Child , Child, Preschool , DNA, Bacterial/analysis , Humans , Infant , Infant, Newborn , Kingella kingae/genetics , Real-Time Polymerase Chain Reaction , Staphylococcus aureus/genetics , Synovial Fluid/microbiology
17.
Med. infant ; 20(1): 13-16, mar. 2013. tab
Article in Spanish | LILACS | ID: lil-774403

ABSTRACT

Kingella kingae es un agente causal de infecciones osteoarticulares especialmente en niños menores de 4 años. En este trabajo se ha realizado un estudio comparativo entre un método molecular [reacción en cadena de la polimerasa (PCR) en tiempo real y dos métodos microbiológicos habitualmente empleados para el estudio de las infecciones osteoarticulares. Sólo se obtuvo resultado positivo para K. kingae por el método de PCR en 3 de las 60 muestras analizadas. Los pacientes evolucionaron sin secuelas aparentes con tratamiento antibiótico. Es importante destacar, como ya lo han hecho otros autores, que adicionando métodos moleculares se puede aumentar sensiblemente la recuperación de este patógeno.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Arthritis, Infectious/diagnosis , Arthritis, Infectious/etiology , Diagnosis , Discitis/diagnosis , Discitis/etiology , Kingella kingae , Molecular Diagnostic Techniques , Polymerase Chain Reaction , Argentina
18.
Article in Spanish | LILACS | ID: lil-686316

ABSTRACT

El objetivo de este trabajo es analizar nuestra experiencia en artritis séptica luego de la reconstrucción artroscópica del LCA. Nive! 4 de evidencia. Se realizó la revisión retrospectiva de las reconstrucciones de ligamento cruzado anterior (LCA) por via artroscópica realizadas en nuestros servicios. Se incluyeron todos los casos diagnosticados como artritis sépticas con un seguimiento mínimo de 1 año. Entre los años 1999 y 2008 se realizaron 1088 reconstrucciones artroscópicas de LCA. Se registraron 12 casos de artritis séptica, lo que implica una incidencia de 1,1 por ciento (IC95 0.6 por ciento - 2 por ciento), los pacientes eran todos de sexo masculino. La edad promedio fue de 27 años (rango entre 21-47). Luego de obtenido el material para cultivo por punción se realizó lavado artroscópico. Se comenzó con terapia antibiótica intravenosa empírica con vancomicina más ciprofloxacina. Al obtener la tipificación se rotó al antibiótico específico endovenoso durante 6 semanas. Se logró conservar el neoligamento en 11 casos (IC95 0,5 por ciento - 1,9 por ciento) y en 1 se perdió. En el seguimiento todos los pacientes presentaron rodillas estables a excepción de un caso. Es de fundamental importancia el trabajo interdisciplinario con el sector de infectología para determinar el tratamiento antibiótico definitivo. La artritis séptica post-reconstrucción de! LCA con diagnóstico precoz y tratamiento efectivo tiene resultados satisfactorios


Subject(s)
Adult , Arthritis, Infectious/diagnosis , Arthritis, Infectious/therapy , Anterior Cruciate Ligament/surgery , Reconstructive Surgical Procedures/adverse effects , Knee Injuries/complications , Anti-Bacterial Agents/therapeutic use , Postoperative Complications , Incidence , Treatment Outcome
19.
Bol. venez. infectol ; 23(1): 42-46, ene.-jun. 2012. graf
Article in Spanish | LILACS | ID: lil-721055

ABSTRACT

La artritis séptica ocurre ocurre por invasión de bacterias a una articulación y si no son diagnosticadas y tratadas a tiempo producen elevada incidencia de secuelas y discapacidad, por lo que son consideradas una urgencia médico-quirúrgicas. Considerando la importancia de esta patología en la edad pediátrica, se realizó un estudio retrospectivo, descriptivo en pacientes con diagnóstico de infección osteoarticualar para evaluar características clínicas, microbiológicas y terapéuticas en el Hospital Universitario de Pediatría "Agustín Zubillaga" entre enero 2008 y marzo 2011. Se revisaron 35 expedientes, encontrándose que la artritis séptica representó 54,2% siendo más frecuente en el sexo masculino en 57,8%. Prodominó en lactantes y escolares con 26,3% respectivamente. La articulación de la cadera fue la más afectada en 52,6%. En 21% de casos se refirió traumatismo de partes blandas como antecedentes. La ecografía de partes blandas fue diagnóstica en 94,7%. Se realizó hemocultivos al 52,6%de casos, de los cuales 80% reportó sin desarrollo bacteriano y en 20% se aisló S. aureus sensibles a meticilina. Las muertes de secreación articular fueron positivas en 50% de los casos, de estos 71,4% correspondió a S. aureus, y 14,3% a Enterobacter sp. El 73,6% recibió oxacilina de inicio siendo necesario el cambio del mismo en un 63,1%. Las infecciones ostearticulares requieren un alto grado de sospechas clínicas por lo que se deben mejorar los procedimientos diagnósticos, a fin de lograr el rápido inicio de la terapéutica antimicrobiana y los procedimientos quirúrgicos adecuados para disminuir el riesgo de secuelas.


Septic arthritis occurs by bacterial invasion of a joint, if it is not diagnosed and treated at time produces a high incidence of sequelae and disabilities, which are considered a medical-surgical emergency. Considering the importance of this disease in children, we conducted a retrospective, descriptive study in patients with osteo-articular infection to assess clinical, microbiological and therapeutic characteristics of these infections in the University Hospital of Pediatrics "Agustic Zubillaga" between January 2008 and March 2011. 35 records were reviewed and we founded septic arthritis to account for 54,2% of them, being more frequent in males (57,8%). It predominated in infants and school age patients with 26,3% respectively. Hip joint was the most affected one in 52,6% of the cases. In 21% of the cases it was involved a soft-tissue injure as an antecedent. Ultrasound of soft tissue was the cause of diagnosis in 94,7% of the cases. Blood culture was performed to 52,6% of case , of which 80% reported no bacterial growoth, and in 20% of them, it was isolated methcillin sensible S. aureus. Articular secretion samples were positive in 50% of cases, 71,4% of these corresponding to S. aureus, and 14,3% to Enterobacter sp. Around 73,6% of patients received oxacillin as a first therapy, and in 63,1% of them therapy must have to be changed. Ostearticular infection requiere a high degree of clinical suspicion, in order to achieve rapid onset of antimicrobial therapy and appropriate surgical procedures to reduce the risk of sequelae.


Subject(s)
Humans , Male , Female , Child , Arthritis, Infectious/diagnosis , Arthritis, Infectious/pathology , Oxacillin , Staphylococcus aureus/pathogenicity , Pediatrics
20.
Rev. Inst. Med. Trop. Säo Paulo ; 54(2): 109-112, Mar.-Apr. 2012. ilus
Article in English | LILACS | ID: lil-625264

ABSTRACT

We present a case of a 16-year-old male patient with sudden-onset, rash, arthritis and meningitis by Neisseria meningitidis one week after an acute upper respiratory infection. On the 10th day of treatment followed by neurological and arthritis clinical improvement, he presented once again a tender and swollen left knee with a moderate effusion, and active and passive range of motion was severely limited secondary to pain, and when he was submitted to surgical drainage and synovial fluid analysis he showed inflammatory characteristics. A non-steroidal anti-inflammatory drug was taken for five days with complete improvement of symptoms. The case is notable for its combination of features of septic and immune-mediated arthritis, which has rarely been reported in the same patient.


Paciente de 16 anos do sexo masculino apresentou-se ao serviço de emergência com quadro de erupção cutânea súbita, artrite e meningite por Neisseria meningitidis, uma semana após apresentar sintomas de infecção de vias aéreas superiores. No décimo dia de tratamento, seguido da melhora clínica neurológica e da artrite, ele volta a apresentar derrame articular moderado com limitação importante da amplitude dos movimentos passivo e ativo secundária à dor. Em seguida, foi submetido à drenagem cirúrgica e a análise do líquido sinovial mostra características inflamatórias. Foi iniciado tratamento com antiinflamatório não esteroidal por cinco dias com melhora completa dos sintomas. Esse caso tem como característica peculiar o fato do indivíduo apresentar tanto as características de artrite séptica pelo meningococo quanto de artrite imunomediada, o que tem sido pouco usual no mesmo paciente.


Subject(s)
Adolescent , Humans , Male , Arthritis, Infectious/immunology , Arthritis, Rheumatoid/immunology , Meningitis, Meningococcal/immunology , Neisseria meningitidis/immunology , Arthritis, Infectious/diagnosis , Arthritis, Rheumatoid/diagnosis
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