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1.
Rev. Odontol. Araçatuba (Impr.) ; 41(2): 28-33, maio-ago.2020. tab, graf
Article in Portuguese | LILACS (Americas), BBO | ID: biblio-1102669

ABSTRACT

O objetivo do presente estudo foi avaliar o pH externo radicular de dentes bovinos pré-selecionados. Neste estudo foram utilizadas soluções irrigadoras, ácido peracético 0,25%, hipoclorito de sódio 2,5% e hipoclorito de sódio 6% associadas ao EDTA e as medicações intracanais, ultracal, hidróxido de cálcio P.A. associado à clorexidina gel 2% e hidróxido de cálcio P.A. associado ao propilenoglicol. O Preparo químico mecânico foi realizado com as limas easy logic e as soluções agitadas com easy clean durante 3 minutos, após os dentes foram imersos em água deionizada em eppendorfs estéreis e mantidos em estufa a 37°C. O pH externo foi mensurado utilizando fitas de pH no período de 3, 24, 72 horas, 7 e 14 dias. A normalidade dos valores obtidos de cada ensaio foi testada através do teste Kolmogorof- Smirnov e o teste estatístico foi ANOVA de uma via e comparações múltiplas de Tukey. Os resultados mostraram que os grupos apresentaram diferença estatística entre eles, entretanto apresentaram alcalinidade durante o período avaliado de 24, 48,72 horas, 7 e 14 dias. Concluiu-se que as soluções associadas às diferentes medicações mostraram pH alcalino, apresentando diferença entre os grupos avaliados nos tempos de 3, 24, 72 horas, 7 e 14 dias, no entanto mostraram resultados satisfatórios, podendo ser utilizados na endodontia(AU)


The objective of the present study was to evaluate the external root pH of pre-selected bovine teeth. In these study irrigation solutions, 0.25% peracetic acid, 2.5% sodium hypochlorite, sodium hypochlorite 6% associated with EDTA and intracanal medications, ultracal, calcium hydroxide PA associated with chlorhexidine gel 2% and P.A. calcium hydroxide associated with propyleneglycol. The mechanical chemical preparation was performed with the easylogic files and the solutions stirred with easy clean for 3 minutes, after the teeth were immersed in deionized water in sterile eppendorfs and kept in an oven at 37 °C. The external pH was measured using pH tapes in the period of 3, 24, 72 hours, 7 and 14 days. The normal values obtained from each test were tested using the KolmogorofSmirnov test and the statistical test chosen was oneway ANOVA and Tukey's multiple comparisons. The results showed that the groups presented statistical difference between them, however they presented alkalinity during the evaluated period of 24, 48, 72 hours, 7 and 14 days. It was concluded that the solutions associated with the different medications showed alkaline pH, presenting a difference between the groups evaluated at 3, 24, 72 hours, 7 and 14 days, however they showed satisfactory results and could be used in endodontics(AU)


Subject(s)
Root Canal Filling Materials , Root Canal Preparation , Peracetic Acid , Root Canal Therapy , Sodium Hypochlorite , Calcium Hydroxide , Chlorhexidine , Edetic Acid , Propylene Glycol
2.
Odontoestomatol ; 22(35): 20-29, jul. 2020. ilus.
Article in Spanish | LILACS (Americas) | ID: biblio-1103033

ABSTRACT

Objetivos: Evaluar la resistencia de unión a la microtracción en dentina humana de un sistema adhesivo universal con clorhexidina en su composición, en modo de grabado y lavado en 2 pasos, y en modo de autograbado. Metodología: 20 terceros molares divididos aleatoriamente en 4 grupos según el tipo de sistema adhesivo utilizado (Single Bond Universal®, 3MESPE y Peak Universal Bond®, Ultradent Products) y modo de uso (grabado total y autograbado). Se confeccionaron cuerpos de prueba sometidos al ensayo de microtracción utilizando una máquina de ensayos universales. Resultados: No se encontraron diferencias estadísticamente significativas entre los cuatro grupos estudiados. Conclusiones: La resistencia de unión de una resina compuesta a dentina humana no fue afectada por el uso de un sistema adhesivo universal que contiene clorhexidina en su composición aplicado en los modos de grabado total y autograbado


Objectives: To evaluate the microtensile bond strength to human dentin of chlorhexidine containing universal adhesive system applied in the total-etch and selfetch modes. Methods: Twenty third molars were randomly divided into four groups according to the universal adhesive system (Single Bond Universal ®, 3M ESPE and Peak Universal Bond®, Ultradent) and application mode used (total-etch and self-etch). Specimens were prepared and subjected to a microtensile bond strength using a MTS SANS universal testing machine. Results: No statistically significant differences were found in the microtensile bond strength between the four groups studied. Conclusions: The bond strength of a composite resin to human dentin was not affected by the use of a universal adhesive system with chlorhexidine in its composition applied in the total-etch and self-etch modes.


Objetivos: Avaliar a resistência de união á microtração na dentina humana de um sistema adesivo universal com clorexidina na sua composição, no modo de condicionamento total em dois passos e no modo autocondicionante. Metodologia: 20 terceiros molares foram divididos aleatoriamente em 4 grupos, de acordo com o tipo de sistema adesivo utilizado (Single Bond Universal®, 3MESPE e Peak Universal Bond®, Ultradent Products) e modo de uso (condicionamento total e autocondicionante). Os corpos de prova criados foram submetidos ao teste de microtração utilizando uma máquina de ensaios universal. Resultados: Não foram encontradas diferenças estatisticamente significativas entre os quatro grupos estudados. Conclusões: A resistência de união da resina composta à dentina humana não foi afetada pelo uso de um sistema adesivo universal contendo clorexidina em sua composição, aplicado nos modos de condicionamento total ou autocondicionamento.


Subject(s)
Tensile Strength , Chlorhexidine , Dental Bonding , Dental Cements
3.
Arq. bras. med. vet. zootec. (Online) ; 72(1): 49-55, Jan.-Feb. 2020. tab, ilus
Article in English | LILACS (Americas), VETINDEX | ID: biblio-1088911

ABSTRACT

The efficacy of an antisepsis protocol comprising chlorhexidine gluconate and ethyl alcohol in combination with prophylactic antimicrobial therapy in controlling surgical site infection in horses was studied. To that purpose, seven mixed breed horses received potassium penicillin and gentamicin at least 30 minutes prior to surgery. The surgical site was scrubbed with chlorhexidine gluconate and rinsed with ethyl alcohol. Samples were collected at four time points: (A) - before and (B) - immediately following shaving of the hair coat, (C) - at the end of antisepsis procedures, and (D) - at the end of the surgical procedure. Duration of surgery was recorded. Samples were cultured in three different culture mediums: Mitis Salivarus (Streptococcus sp.), Staphylococcus 110 (Staphylococcus sp.), and Mac Conkey (Enterobacteria). A high level of bacterial growth was observed in all culture mediums at (A) and (B), with no bacterial growth in (C). Staphylococcus sp. growth was observed in (D) in a single patient whose surgical procedure lasted for 120 minutes. Shaving of the hair coat reduced microbial flora on the surface of the skin. Antisepsis in combination with prophylactic antimicrobial therapy was effective in controlling surgical site infection in elective procedures with an average duration of 90 minutes.(AU)


Objetivou-se averiguar a eficácia do protocolo de antissepsia com clorexidina degermante e álcool etílico hidratado 70%, em associação com terapia antimicrobiana profilática, no controle microbiano do foco cirúrgico de equinos submetidos a procedimentos cirúrgicos. Foram utilizados 07 cavalos adultos de raças variadas, onde ambos receberam o mesmo tratamento (terapia antimicrobiana profilática e antissepsia com clorexidina degermante 2% e álcool etílico hidratado 70%), coletando-se amostras em quatro tempos distintos [(A - antes da tricotomia), (B - imediatamente após tricotomia), (C - ao término da antissepsia), (D - ao término do procedimento cirúrgico)]. O tempo de cada procedimento cirúrgico foi contabilizado. Foram utilizados três meios de cultura diferentes, cada um com especificidade para um tipo de crescimento bacteriano. Constatou-se alta incidência de crescimento bacteriano nos três meios utilizados nos tempos de coleta A e B. Para o tempo C, não foi observado crescimento bacteriano. No tempo D averiguou-se crescimento bacteriano do tipo Staphylococcus sp. em um único paciente, cujo tempo cirúrgico foi de 120 minutos de duração. Desta forma, a tricotomia reduziu a carga microbiana na superfície da pele. A antissepsia associada à terapia antimicrobiana profilática mostrou-se eficaz no controle microbiano do foco cirúrgico em procedimentos eletivos, com duração média de 90 minutos.(AU)


Subject(s)
Animals , Penicillins , Staphylococcus , Chlorhexidine , Antisepsis , Horses/surgery , Anti-Infective Agents/therapeutic use , Surgical Procedures, Operative/veterinary
4.
Braz. dent. sci ; 23(2): 1-7, 2020. tab
Article in English | LILACS (Americas), BBO | ID: biblio-1096501

ABSTRACT

Background: glass ionomer is one of the most frequently used restorative materials for primary teeth restoration. It has been in use for more than 30 years. Their restoration usefulness is preferential compared to other restorations due to their fluoride release and recharge, chemical adhesion to the structure of the dentin and their range of uses. Increasing the antibacterial efficacy of restorative materials is one of the primary goals to decrease the incidence of recurrent caries. Chlorhexidine is the gold standard antibacterial agent in dentistry. Objectives: the objective of this study is to evaluate the antibacterial effect of Chlorhexidine incorporated with glass ionomer on Streptococcus mutans. Methods: Thirty Children between ages ranged 6-9 years old were selected to participate in this study. Children with bilateral caries in lower second primary molars affecting the occlusal and proximal surfaces without pulpitis were included in the study. All cavities were divided into two groups; group (A) restored with Glass Ionomer and group (B) restored with Glass Ionomer Chlorhexidine mixture. The sound proximal surfaces in all cavitated teeth acted as a control. After one month, two months and three months' plaque samples were obtained and Streptococcus mutans counts were calculated. Results: The number of SM taken from sound proximal surfaces for all groups were not changed significantly in whole periods of study. At the all-time interval, the mean log10 of SM in group B was lower than group A and the difference was statistically significant. There is a significant difference in the mean log10 of SM in group B between the 1St month and the 3rd month. Conclusion: The growth of SM was found to be higher in the sound tooth than in GI groups and in GI group was higher than in CHX- GI mixture up to three months (AU)


Antecedentes: o ionômero de vidro é um dos materiais restauradores mais utilizados na restauração de dentes decíduos. É usado há mais de 30 anos. Sua indicação como material restaurador em comparação a outros baseia-se nas propriedades de liberação e recarga de flúor, adesão química à estrutura da dentina e sua variedade de usos. Aumentar a eficácia antibacteriana de materiais restauradores é um dos principais objetivos para diminuir a incidência de cárie recorrente. A clorexidina é o agente antibacteriano padrão-ouro em odontologia. Objetivos: o objetivo deste estudo é avaliar o efeito antibacteriano da Clorexidina incorporada ao ionômero de vidro no Streptococcus mutans (SM). Métodos: Trinta crianças entre 6 e 9 anos foram selecionadas para participar deste estudo. Crianças com cárie bilateral nos segundos molares decíduos inferiores que afetavam as superfícies oclusal e proximal sem pulpite foram incluídas no estudo. Todas as cavidades foram divididas em dois grupos; grupo A, restaurado com Ionômero de Vidro e grupo B, restaurado com mistura de Ionômero de Vidro /Clorhexidina. As superfícies proximais sadias em todos os dentes cavitados atuavam como controle. Após um mês, dois e três meses, foram obtidas amostras de placa e as contagens de Streptococcus mutans foram realizadas. Resultados: O número de SM retirado da superfície proximal sadia para todos os grupos não foi alterado significativamente nos períodos do estudo. No intervalo de todos os tempos, o log10 médio da SM no grupo B foi menor que no A e a diferença foi estatisticamente significante. Há uma diferença significativa no log10 médio da SM no grupo B entre o 1º mês e o 3º mês. Conclusão: O crescimento da SM mostrou-se maior no dente sadio do que nos grupos A; e no grupo A foi maior que no grupo B até três meses.(AU)


Subject(s)
Humans , Child , Streptococcus mutans , Chlorhexidine , Glass Ionomer Cements
5.
Article in Korean | WPRIM (Western Pacific) | ID: wprim-786597

ABSTRACT

PURPOSE: The aim of this study is to evaluate the effectiveness of MnO₂-diatom microbubbler (DM) on the surface of prosthetic materials as a mouthwash by comparing the biofilm removal effect with those previously used as a mouthwash in dental clinic.MATERIALS AND METHODS: DM was fabricated by doping manganese dioxide nanosheets to the diatom cylinder surface. Scanning electron microscopy (SEM) was used to observe the morphology of DM and to analyze the composition of doped MnO₂. Stereomicroscope was used to observe the reaction of DM in 3% hydrogen peroxide. Non-precious metal alloys, zirconia and resin specimens were prepared to evaluate the effect of biofilm removal on the surface of prosthetic materials. And then Streptococcus mutans and Porphyromonas gingivalis biofilms were formed on the specimens. When 3% hydrogen peroxide solution and DM were treated on the biofilms, the decontamination effect was compared with chlorhexidine gluconate and 3% hydrogen peroxide solution by crystal violet staining.RESULTS: Manganese dioxide was found on the surface of the diatom cylinder, and it was found to produce bubble of oxygen gas when added to 3% hydrogen peroxide. For all materials used in the experiments, biofilms of the DM-treated groups got effectively removed compared to the groups used with chlorhexidine gluconate or 3% hydrogen peroxide alone.CONCLUSION: MnO₂-diatom microbubbler can remove bacterial membranes on the surface of prosthetic materials more effectively than conventional mouthwashes.


Subject(s)
Alloys , Biofilms , Chlorhexidine , Decontamination , Dental Clinics , Dental Plaque , Diatoms , Gentian Violet , Hydrogen Peroxide , In Vitro Techniques , Manganese , Membranes , Microscopy, Electron, Scanning , Mouthwashes , Oral Hygiene , Oxygen , Porphyromonas gingivalis , Streptococcus mutans
6.
Actual. osteol ; 15(3): 225-236, Sept-Dic. 2019. ilus
Article in English | LILACS (Americas) | ID: biblio-1116171

ABSTRACT

Bone grafting is important to preserve the alveolar bone ridge height and volume for dental implant placement. Even though implant-supported overdentures present highly successful outcomes, it seems that a great number of edentulous individuals have not pursued implant-based rehabilitation. The cost of the treatment is one of the reasons of discrepancy between highly successful therapy and its acceptance. Therefore, the development of biomaterials for bone grafting with comparable characteristics and biological effects than those renowned internationally, is necessary. In addition, domestic manufacture would reduce the high costs in public health arising from the application of these biomaterials in the dental feld. The purpose of this clinical case report is to provide preliminary clinical evidence of the efficacy of a new bovine bone graft in the bone healing process when used for sinus floor elevation. (AU)


El uso de injertos óseos es importante para preservar la altura y el volumen de la cresta alveolar para la colocación de implantes dentales. Si bien las sobredentaduras implanto-soportadas presentan resultados altamente exitosos, la mayoría de las personas desdentadas no han sido rehabilitadas mediante implantes dentales. Uno de los principales motivos por los cuales los pacientes no aceptan este tipo de tratamiento, altamente exitoso, es el elevado costo del mismo. Por ello, es necesario el desarrollo de biomateriales de injerto óseo con características y efectos biológicos comparables a los reconocidos internacionalmente. Asimismo, la fabricación nacional reduciría los altos costos en Salud Pública derivados de la aplicación de estos biomateriales en el campo dental. El objetivo de esta comunicación es presentar un caso clínico a fin de proporcionar evidencia preliminar acerca de la eficacia de un nuevo injerto de hueso bovino en el proceso de cicatrización ósea en el levantamiento del piso del seno maxilar. (AU)


Subject(s)
Humans , Animals , Female , Middle Aged , Cattle , Rats , Bone Transplantation/methods , Jaw, Edentulous, Partially/rehabilitation , Sinus Floor Augmentation/methods , Osteogenesis , Argentina , Biocompatible Materials , Cattle/physiology , Carticaine/administration & dosage , Chlorhexidine/administration & dosage , Naproxen/administration & dosage , Public Health/economics , Osseointegration , Dentures , Bone Transplantation/trends , Jaw, Edentulous, Partially/pathology , Jaw, Edentulous, Partially/therapy , Durapatite/therapeutic use , Amoxicillin-Potassium Clavulanate Combination/administration & dosage , Dental Implantation, Endosseous/methods , Sinus Floor Augmentation/trends , Allografts/immunology , Allografts/transplantation
7.
Rev. Ateneo Argent. Odontol ; 61(2): 36-40, nov. 2019. ilus
Article in Spanish | LILACS (Americas) | ID: biblio-1095356

ABSTRACT

La osteonecrosis de los maxilares asociada a bifosfonatosfuedefinida como «Área de hueso expuesto en la región máxilo facial que permanece expuesta al menos por 8 semanas, siempre que los pacientes hayan sido prescriptos con bifosfonatos, y en ausencia de terapia radiante¼. (1) En la actualidad se agregó "hueso expuesto o hueso que se puede sondear a través de una fistula intra o extra oral" (2). Presentamos un caso clínico de una paciente femenina de 70 años de edad, diagnosticada con cáncer de hueso (osteosarcoma) con foco en la pelvis, historia de consumo de bifosfonatosvía endovenosa durante tres años, zolendronato 70mg, semanalmente. Al momento de la consulta, se encontraba en periodo de remisión de la enfermedad de base y sin consumo de medicación antiresortiva desde hace un año (AU)


Osteonecrosis of the jaws associated with bisphosphonates was defined as «Area of exposed bone in the maxillofacial region that remains exposed for at least 8 weeks, provided that patients have been prescribed with bisphosphonates, and in the absence of radiant therapy¼. (1) At present, "exposed bone or bone that can be probed through an intra or extra oral fistula" was added (2). We present a clinical case of a 70-year-old female patient, diagnosed with bone cancer (osteosarcoma) with a focus on the pelvis, history of consumption of bisphosphonates intravenously for three years, zolendronate 70 mg, weekly. At the time of the consultation, he was in the period of remission of the underlying disease and without consumption of antiresortive medication for a year (AU)


Subject(s)
Humans , Female , Aged , Bone Resorption/etiology , Alveolar Bone Loss/etiology , Diphosphonates/adverse effects , Bisphosphonate-Associated Osteonecrosis of the Jaw , Chlorhexidine/therapeutic use , Amoxicillin-Potassium Clavulanate Combination/therapeutic use , Dental Service, Hospital , Bisphosphonate-Associated Osteonecrosis of the Jaw/diagnostic imaging
8.
Dent. press endod ; 9(1): 37-42, jan.-mar. 2019. tab, Ilus
Article in Portuguese | LILACS (Americas), BBO | ID: biblio-1007600

ABSTRACT

Objetivo: avaliar a resistência máxima à flexão (MFS), módulo de elasticidade (E), microdureza Knoop (KHN) e rugosidade de superfície (Ra) da dentina radicular tratada com solução de clorexidina a 2% (CHX). Métodos: foram selecionados 50 incisivos bovinos com ápice fechado, e trinta raízes foram cortadas em barras de dentina (DB) e divididas em três grupos (n = 10): Controle (sem tratamento), G1 (NaOCl 2,5% + EDTA 17%) e G2 (CHX 2% + H2O). As DB foram submetidas ao ensaio de resistência flexural de três pontos, para se obter os valores de MFS e E. Vinte raízes foram cortadas longitudinalmente ao meio e inseridas em resina acrílica; as superfícies pulpares foram lixadas e polidas e, em seguida, irrigadas de acordo com o grupo (G1 ou G2; n = 20 metades por grupo) e submetidas aos testes de KHN e Ra. Foi realizada análise de MEV. Os dados foram analisados por meio dos testes de ANOVA de um e dois critérios, seguidos do teste de Tukey (α = 0,05). Resultados: os valores de MFS (p < 0,05) e E (p < 0,01) foram maiores para G2. A KHN foi reduzida após o tratamento com cada irrigante endodôntico (p < 0,001), sem diferenças entre eles (p = 0,115). A Ra foi maior para o G1 (p < 0,001). Conclusões: a solução de clorexidina a 2% melhora as propriedades mecânicas de MFS, E e Ra da dentina radicular. (AU)


Objective: To evaluate the maximum flexural strength (MFS), elastic modulus (E), Knoop microhardness (KHN), and surface roughness (Ra) of root dentin treated with 2% chlorhexidine (CHX) solution. Materials and methods: Fifty bovine incisors with closed apex were selected. Thirty roots were cut into dentin bars (DB) and divided into three groups (n=10): control (no treatment), G1 (2.5% NaOCl + 17% EDTA) and G2 (2% CHX + H2O). The DB were submitted to the three-point flexural strength test to obtain the MFS and E. Twenty roots were cut longitudinally into two half-halves and placed in acrylic resin. The pulp surfaces were sanded and polished. They were rinsed according to the group (G1 or G2; n = 20 per group) and subjected to the KHN and Ra tests. SEM analysis was made. Data were analysed by one- and two-way ANOVA and Tukey post hoc test (a = 0.05). Results: The values of MFS (P < 0.05) and E (P < 0.01) were higher for G2. The KHN reduced after both endodontic irrigation treatments (P < 0.001), with no differences between them (P = 0.115). Ra was higher for G1 (P < 0.001). Conclusions: 2% CHX improved the mechanical properties of MFS, E and Ra of root dentin (AU).


Subject(s)
Chlorhexidine , Dental Pulp Cavity , Dentin , Sodium Hypochlorite
9.
Pesqui. bras. odontopediatria clín. integr ; 19(1): 4296, 01 Fevereiro 2019. tab, graf
Article in English | LILACS (Americas), BBO | ID: biblio-997914

ABSTRACT

Objective: To evaluate in the vitro effectiveness of three chemical agents for toothbrush disinfection. Material and Methods: Sixteen new toothbrushes were evaluated, previously sterilized and classified in five experimental groups (n=3) and one item as control. Three chemical agents were assessed: 0.12% Chlorhexidine gluconate (CHX), essential oil mouth rinse (Listerine) and 3.5% Sodium hypochlorite (NaOCl). The five selected strains were inoculated on toothbrushes and incubated for a 24 hours period and 37°C temperature in aerobic conditions. The incubated toothbrushes were immersed for a 15 min period into selected chemical agents and after drying in a controlled air stream, again re-cultured into enriched broth. A comparison was made between the initial and final microorganisms density recovered after chemical disinfection based on Mc Farland scale. The data obtained was compared by descriptive analysis and ANOVA methodology. Results: 3.5% NaOCl was the most effective chemical agent for toothbrush disinfection followed by CHX; Listerine was not effective to eliminate the inoculated bacteria in toothbrushes. Conclusion: 3.5% NaOCl and 0.12% CHX are the most effective chemical agents for toothbrush disinfection and Listerine was only effective against C. albicans.


Subject(s)
Candida albicans , Chlorhexidine , Disinfection/methods , Chemical Compounds , Mouthwashes/analysis , Toothbrushing/methods , Venezuela , In Vitro Techniques/methods , Analysis of Variance
10.
REME rev. min. enferm ; 23: e-1263, jan.2019.
Article in Portuguese | LILACS (Americas), BDENF | ID: biblio-1047867

ABSTRACT

As infecções do trato urinário relacionadas ao cateterismo urinário de demora estão entre as mais frequentes em hospitais. Existem várias recomendações para a prevenção de infecções, porém ainda se questiona a necessidade de utilizar antissépticos para a limpeza periuretral. Objetivo: este estudo objetivou analisar as evidências, na literatura, acerca do tema. Método: foi realizada revisão sistemática utilizando-se as bases de dados Biblioteca Virtual em Saúde, Medline, Embase, Web of Science e Cumulative Index to Nursing & Allied Health Literature. Foram incluídos ensaios clínicos que avaliaram as taxas de infecção do trato urinário/bacteriúria e que utilizaram soluções antissépticas e água na limpeza periuretral. Resultados: de 211 estudos, três foram considerados metodologicamente adequados de acordo com a Escala de Jadad. Todos os estudos mostraram que não há diferenças significativas nas taxas de ITU/ bacteriúria quando comparado o uso de água com antisséptico (clorexidina ou povidona-iodo). Conclusão: concluiu-se que o uso de água na limpeza periuretral parece não aumentar o risco de adquirir infecção/bacteriúria.(AU)


Urinary tract infections related to indwelling urinary catheterization are among the most frequent in hospitals. There are many recommendations for the prevention of infections, but the need to use antiseptics for periurethral cleaning is still questioned. Objective: This study aimed to analyze the evidence on the theme in the literature. Method: A systematic review was performed using the following databases: Biblioteca Virtual em Saúde, Medline, Embase, Web of Science and Cumulative Index to Nursing & Allied Health Literature. Clinical trials were included which assessed the infection rates of the urinary tract/bacteriuria and which used antiseptic solutions and water in the periurethral cleaning. Results: Of 211 studies, three were considered as methodologically adequate according to the Jadad Scale. All of the studies showed that there is no significant difference in the rates of UTI/bacteriuria when compared to the use of water with antiseptic (chlorhexidine or povidone-iodine). Conclusion: It was concluded that the use of water in the periurethral cleaning seems not to augment the risk of acquiring infections/bacteriuria.(AU)


Las infecciones del tracto urinario relacionadas con el cateterismo urinario permanente se encuentran entre las infecciones hospitalarias más comunes. Existen recomendaciones para la prevención de infecciones, pero aún se cuestiona la necesidad de usar antisépticos para la limpieza periuretral. Objetivo: analizar la evidencia en la literatura sobre el tema. Método: se realizó una revisión sistemática utilizando las bases de datos de la Biblioteca Virtual de Salud, Medline, Embase, Web of Science y Cumulative Index to Nursing & Allied Health Literature. Se incluyeron ensayos clínicos que evaluaron las tasas de infección urinaria / bacteriuria y el uso de soluciones antisépticas y agua para la limpieza periuretral. Resultados: de 211 estudios, tres se consideraron metodológicamente adecuados según la escala de Jadad. Todos los estudios mostraron que no hay diferencias significativas en las tasas de infección urinaria / bacteriuria en comparación con el uso de agua antiséptica (clorhexidina o povidona yodada). Conclusión: el uso de agua para la limpieza periuretral no parece aumentar el riesgo de contraer infección / bacteriuria.(AU)


Subject(s)
Urinary Tract Infections , Urinary Catheterization , Anti-Infective Agents, Urinary , Povidone-Iodine , Water , Chlorhexidine
11.
Arq. odontol ; 55: 1-8, jan.-dez. 2019. tab
Article in Portuguese | LILACS (Americas), BBO | ID: biblio-1051618

ABSTRACT

Objetivo:O presente estudo piloto "in vitro" avaliou o efeito antimicrobiano do hipoclorito de sódio, clorexidina, terapia fotodinâmica e do óleo de girassol ozonizado utilizados como agentes irrigantes na eliminação do Enterococcus faecalis em canais radiculares de dentes humanos extraídos.Métodos:Sessenta raízes de dentes unirradiculares (n = 60) foram selecionadas e autoclavadas para realização do experimento em fluxo laminar. Para a realização do teste de infiltração, confeccionou-se um dispositivo para cada denteque permitiu a contaminação por Enterococcus faecalis e posterior preparo químico-mecânico. As amostras foram submetidas ao preparo biomecânico com diâmetro cirúrgico correspondente à lima #45 e mesma conicidade nos terços médio e cervical e receberam protocolo de desinfecção com hipoclorito de sódio a 2,5% (NaOCl), Clorexidina a 2% (CHX), óleo de girassol ozonizado a 2400ppm (OGO), PDT após irrigação com soro fisiológico (PDT+S) e PDT após irrigação com hipoclorito de sódio a 2,5% (PDT+H). As dez raízes restantes constituíram os controles positivo e negativo, sendo cinco dentes para cada grupo. Os controles positivos foram infectados e não foi utilizado nenhum agente irrigante. Os controles negativos foram compostos por dentes não contaminados pelo E. faecallis. Resultados: Os resultados da contagem de UFC/mL total e análise descritiva foram realizados. NaOCl e PDT+H apresentaram crescimento bacteriano inferiores aos valores de referência e foi considerado nulo. CHX e PDT+S apresentaram crescimento bacteriano baixo e OGO apresentou crescimento bacteriano moderado. Conclusão: NaOCl e PDT+H apresentaram melhor desempenho em relação aos demais protocolos de desinfecção utilizados. OGO apresentou crescimento bacteriano moderado sugerindo inviabilidade de sua utilização isolada em protocolos de desinfecção em endodontia. (AU)


Aim: The present "in vitro" pilot study evaluated the antimicrobial effects of sodium hypochlorite, chlorhexidine, photodynamic therapy, and ozonated sunflower oil, which were used as irrigating agents in the elimination of Enterococcus faecalis in the root canals of extracted human teeth. Methods: Sixty roots of single-root teeth (n = 60) were selected and autoclaved to perform the laminar flow experiment. To perform the infiltration test, a device was constructed for each tooth, which allowed for contamination by Enterococcus faecalis, and the tooth's subsequent chemical-mechanical preparation. The samples were submitted to biomechanical preparation with surgical diameter, corresponding to file #45 and the same taper in the middle and cervical thirds, and received a disinfection protocol with 2.5% sodium hypochlorite (NaOCl), chlorhexidine 2% (CHX), ozonized sunflower oil at 2400ppm (OGO), PDT after irrigation with saline solution (PDT+S), and PDT after irrigation with 2.5% sodium hypochlorite (PDT + H). The remaining ten roots were positive and negative controls, with five teeth in each group. Positive controls were infected, and no irrigating agent was used. Negative controls consisted of teeth that were not contaminated by E. faecallis. Results: The results of the total CFU count and descriptive analysis were performed. NaOCl and PDT+H presented a bacterial growth of much lower t than the reference values and was considered null. CHX and PDT+S presented low bacterial growth, while OGO presented moderate bacterial growth. Conclusion: NaOCl and PDT + H presented better performance in relation to the other disinfection protocols used in this study. OGO presented moderate bacterial growth, suggesting its unviable use in endodontic disinfection protocols. (AU)


Subject(s)
Photochemotherapy , Root Canal Irrigants , Sodium Hypochlorite/administration & dosage , Chlorhexidine/administration & dosage , Disinfection , Enterococcus faecalis , Sunflower Oil/administration & dosage , Anti-Infective Agents/administration & dosage , In Vitro Techniques
12.
Article in English | WPRIM (Western Pacific) | ID: wprim-760191

ABSTRACT

Newborn infants, including premature infants, are high-risk patients susceptible to various microorganisms. Catheter-related bloodstream infections are the most common type of nosocomial infections in this population. Regular education and training of medical staffs are most important as a preventive strategy for central line-associated bloodstream infections (CLABSIs). Bundle approaches and the use of checklists during the insertion and maintenance of central catheters are effective measures to reduce the incidence of CLABSIs. Chlorhexidine, commonly used as a skin disinfectant before catheter insertion and dressing replacement, is not approved for infants <2 months of age, but is usually used in many neonatal intensive care units due to the lack of alternatives. Chlorhexidine-impregnated dressing and bathing, recommended for adults, cannot be applied to newborns. Appropriate replacement intervals for dressing and administration sets are similar to those recommended for adults. Umbilical catheters should not be used longer than 5 days for the umbilical arterial catheter and 14 days for the umbilical venous catheter. It is most important to regularly educate, train and give feedback to the medical staffs about the various preventive measures required at each stage from before insertion to removal of the catheter. Continuous efforts are needed to develop effective and safe infection control strategies for neonates and young infants.


Subject(s)
Adult , Bacteremia , Bandages , Baths , Catheters , Central Venous Catheters , Checklist , Chlorhexidine , Cross Infection , Education , Humans , Incidence , Infant , Infant, Newborn , Infant, Premature , Infection Control , Intensive Care Units , Intensive Care Units, Neonatal , Medical Staff , Skin
13.
Article in English | WPRIM (Western Pacific) | ID: wprim-788761

ABSTRACT

OBJECTIVE: Hydatid cyst disease is caused by the parasite Echinococcus granulosus. It is rarely seen in the vertebral system, occurring at a rate of 0.2–1%. The aim of this study is to present 12 spinal hydatid cyst cases, and propose a new type of drainage of the cyst.METHODS: Twelve cases of spinal hydatid cysts, surgical operations, multiple operations, chronic recurrences, and spinal hydatic cyst excision methods are discussed in the context of the literature. Patients are operated between 2005 and 2016. All the patients are kept under routine follow up. Patient demographic data and clinicopathologic characteristics are examined.RESULTS: Six male and six female patients with a median age of 38.6 at the time of surgery were included in the study. Spinal cyst hydatid infection sites were one odontoid, one cervical, five thoracic, two lumbar, and three sacral. In all cases, surgery was performed, with the aim of total excision of the cyst, decompression of the spinal cord, and if necessary, stabilization of the spinal column. Mean follow up was 61.3 months (10–156). All the patients were prescribed Albendazole. Three patients had secondary hydatid cyst infection (one lung and two hepatic).CONCLUSION: The two-way drainage catheter placed inside a cyst provides post-operative chlorhexidine washing inside the cavity. Although a spinal hydatid cyst is a benign pathology and seen rarely, it is extremely difficult to achieve a real cure for patients with this disease. Treatment modalities should be aggressive and include total excision of cyst without rupture, decompression of spinal cord, flushing of the area with scolicidal drugs, and ensuring spinal stabilization. After the operation the patients should be kept under routine follow up. Radiological and clinical examinations are useful in spotting a recurrence.


Subject(s)
Albendazole , Catheters , Chlorhexidine , Decompression , Drainage , Echinococcosis , Echinococcus granulosus , Female , Flushing , Follow-Up Studies , Humans , Lung , Male , Metrorrhagia , Parasites , Pathology , Recurrence , Rupture , Spinal Cord , Spine
14.
Article in Korean | WPRIM (Western Pacific) | ID: wprim-738618

ABSTRACT

PURPOSE: To report a case of chemical injury of the cornea caused by high-dose ethanol during orbital wall fracture repair. CASE SUMMARY: A 56-year-old male presented with pain after blowout fracture repair surgery. During the surgery, 2% hexethanol solution (2% chlorhexidine and 72% ethanol mixture), which was used for disinfection of the face, flowed into the left eye. Conjunctival injection in the left limbus, a large corneal epithelial defect, and severe stromal edema were subsequently observed. The patient was treated with topical antibiotics, steroids, and autologous serum eye drops. After 1 week, the corneal epithelial defect was improved, but at the second month of therapy, recurrent corneal erosion with deterioration of the endothelial cell function occurred. Anterior stromal puncture and laser keratectomy were performed. The corneal epithelial defect and erosion improved, but the endothelial cell density was severely decreased. CONCLUSIONS: The 2% hexethanol solution is usually used for preoperative skin disinfection, but it contains a high concentration of ethanol. The surgeon should be aware that high concentrations of ethanol may result in severe corneal damage, including corneal endothelial dysfunction and limbal cell deficiency.


Subject(s)
Anti-Bacterial Agents , Chlorhexidine , Cornea , Corneal Injuries , Corneal Surgery, Laser , Disinfection , Edema , Endothelial Cells , Ethanol , Humans , Male , Middle Aged , Ophthalmic Solutions , Orbit , Punctures , Skin , Steroids
15.
Rev. latinoam. enferm. (Online) ; 27: e3106, 2019. graf
Article in English | LILACS (Americas), BDENF | ID: biblio-985656

ABSTRACT

ABSTRACT Objective: to compare the effect of dry care and the application of chlorhexidine to the umbilical cord of newborns at risk of developing omphalitis. Method: systematic review with meta-analysis. Clinical trials comparing dry care with the application of clorexidine to evaluate omphalitis were selected. Methodological quality was evaluated using the Consolidated Standards of Reporting Trials. Results: the joint analysis of the studies shows a significant decrease in the risk of omphalitis in the chlorhexidine group compared to the dry care group (RR=0.58, CI: 0.53-0.64). However, in the analysis by subgroups, chlorhexidine umbilical cord care did not reduce the risk of omphalitis in hospital births (RR=0.82, CI: 0.64-1.05), in countries with a low infant mortality rate (RR=0.8, CI: 0.5-1.28), or at chlorhexidine concentrations below 4% (RR=0.55, CI: 0.31-1). Chlorhexidine acted as a protective factor at a concentration of 4% (RR=0.58, CI: 0.53-0.64), when applied in cases of home births (RR=0.57, CI: 0.51-0.62), in countries with a high infant mortality rate (RR=0.57, CI: 0.52-0.63). Conclusion: dry cord care is effective in countries with low infant mortality rate and in hospital births. However, 4% chlorhexidine for umbilical cord care protects against omphalitis in home births, in countries with a high infant mortality rate.


RESUMO Objetivo: comparar o efeito da cura a seco e da aplicação de clorexidina no cordão umbilical de recém-nascidos em risco de desenvolver onfalite. Método: revisão sistemática com metanálise. Foram selecionados os ensaios clínicos que comparavam a cura a seco com a aplicação de clorexidina para avaliar a onfalite. A qualidade metodológica foi avaliada com Consolidated Standards of Reporting Trials. Resultados: a análise conjunta dos estudos mostra uma redução significativa do risco de onfalite no grupo da clorexidina em comparação com a cura a seco (RR=0,58; IC 0,53-0,64). Entretanto, na análise por subgrupos, a cura com clorexidina não reduziu o risco de onfalite em nascimentos hospitalares (RR=0,82; IC: 0,64-1,05), nos países com baixa taxa de mortalidade infantil (RR=0,8; IC: 0,5-1,28), ou com concentrações de clorexidina abaixo de 4% (RR=0,55; IC: 0,31-1). A clorexidina atuou como fator de proteção na concentração de 4% (RR=0,58; IC: 0,53-0,64), aplicada em nascimentos no domicílio (RR=0,57; IC: 0,51-0,62), em países com taxas de mortalidade infantil elevadas (RR=0,57; IC: 0,52-0,63). Conclusão: a cura a seco é eficaz em países com baixa taxa de mortalidade infantil e em nascimentos no contexto hospitalar. No entanto, a cura com clorexidina 4% protege contra a onfalite nos nascimentos domiciliares, em países com elevada mortalidade infantil.


RESUMEN Objetivo: comparar el efecto de la cura seca y de la aplicación de clorhexidina en el cordón umbilical de los recién nacidos en el riesgo de desarrollo de onfalitis. Método: revisión sistemática con metaanálisis. Se seleccionaron ensayos clínicos que compararan la cura seca con la aplicación de clorhexidina evaluando la onfalitis. Calidad metodológica evaluada con Consolidated Standards of Reporting Trials. Resultados: el análisis conjunto de los estudios muestra una reducción significativa del riesgo de onfalitis en el grupo de clorhexidina en comparación con cura seca (RR=0,58; IC: 0,53-0,64). Sin embargo, en el análisis por subgrupos, la cura con clorhexidina no aportó reducción del riesgo de onfalitis en nacimientos hospitalarios (RR=0,82; IC: 0,64-1,05) en países con baja tasa de mortalidad infantil (RR=0,8; IC: 0,5-1,28), ni a concentraciones de clorhexidina inferiores al 4% (RR=0,55; IC: 0,31-1). La clorhexidina actuó como factor protector a concentraciones del 4% (RR=0,58; IC: 0,53-0,64), aplicada en nacimientos en el hogar (RR=0,57; IC: 0,51-0,62), en países con elevada mortalidad infantil (RR=0,57; IC: 0,52-0,63). Conclusión: la cura seca es eficaz en países con baja tasa de mortalidad infantil y nacimientos en ámbito hospitalario. Sin embargo, la cura con clorhexidina al 4% protege de onfalitis en nacimientos en el hogar, en países con elevada mortalidad infantil.


Subject(s)
Humans , Male , Female , Infant, Newborn , Umbilical Cord/physiology , Chlorhexidine/therapeutic use , Skin Care/methods
16.
Rev. Salusvita (Online) ; 38(1): 87-96, 2019.
Article in Portuguese | LILACS (Americas) | ID: biblio-1051044

ABSTRACT

Introdução: os enxaguatórios representam o meio mais simples para a veiculação de substâncias antissépticas, sendo uma mistura do componente ativo, água, álcool, surfactantes, umectantes e flavorizantes. Objetivo: este trabalho avaliou, a curto prazo, o potencial antimicrobiano e profilático de enxaguatórios bucais contendo em sua formulação clorexidina e óleos essenciais. Métodos: foram selecionados, de forma aleatória, vinte pacientes adultos submetidos a diversos tratamentos na Clínica Integrada do Curso de Odontologia da UNIVALI, os quais posteriormente foram divididos em dois grupos (Grupo A submetido à profilaxia com Periogard® e grupo B com Listerine®). Nos dois grupos, anteriormente à profilaxia, foi retirada uma amostra controle proveniente da parte interna da bochecha direita e a seguir realizada a profilaxia com 15 ml do enxaguatório correspondente ao seu grupo, por um período de 1 minuto. Após 5 minutos, foi realizada a coleta de uma nova amostra, da bochecha esquerda, fazendo-se 3 esfregaços com Swab estéril. As amostras foram depositadas em tubo de rosca com salina estéril e encaminhadas para o laboratório de Microbiologia do Centro de Ciências da Saúde (CCS-UNIVALI). Para análise, as amostras foram agitadas por 2 minutos em Vortex e em seguida as soluções foram semeadas em duplicata, em placas com meio de cultura Agar Mueller Hinton (Oxoid) para contagem de células bacterianas. Resultados e Discussão: após análise dos resultados, pôde-se observar que o os enxaguatórios Listerine® e Periogard® apresentaram eficiência em 80,9% e 95,9% das bactérias de seus grupos, respectivamente. Conclusão: conclui-se que os enxaguatórios analisados apresentaram capacidade de redução do percentual inicial de bactérias. Comparando-se os resultados encontrados, percebeu-se que o enxaguatório contendo clorexidina 0,12% apresentou-se mais eficiente.


Introduction: this study investigated the antimicrobial prophylactic potential of mouthwashes containing chlorhexidine and essential oils in its formulation. Method: twenty adult patients were submitted to various treatments at the integrated clinic of UNIVALI dentistry course were selected randomly. They were divided into two groups (Group A submitted to prophylaxis with Periogard® and group B with Listerine®). In both groups, control samples were taken from the inside of the right cheek and subsequently submitted to the prophylaxis with 15 ml of the mouthwash to its corresponding group for a period of 1 minute. After 5 minutes, a new sample was collected from the left cheek, making up 3 smears with sterile swab. The samples were placed in screw-tube with sterile saline and sent to the microbiology laboratory of the Centro de Ciências da Saúde (CCS-UNIVALI). For analysis the samples were shaken on a vortex for 2 minutes and then the solutions were seeded in duplicate on plates with medium Mueller Hinton Agar (Oxoid) culture to bacterial cell count. Discussion: The results showed that the mouthwashes Listerine® and Periogard® presented efficiency of 80,9% and 95,9% of bacteria, respectively. Both analyzed mouthwashes decreased the initial bacterial percentage. Conclusion: comparing the results, it was concluded that the mouthwashes containing 0.12% chlorhexidine in their formulation were more efficient.


Subject(s)
Humans , Mouthwashes , Chlorhexidine , Disease Prevention
17.
Rev. odontol. UNESP (Online) ; 48: e20190020, 2019. tab, graf, ilus
Article in English | LILACS (Americas), BBO | ID: biblio-1043173

ABSTRACT

Abstract Introduction The attachment of fiberglass posts is achieved through an adhesive process. Failures in adhesion may occur due to the hydrolytic degradation of the adhesives, or to the degradation of the collagen fibres of the hybrid layer by intrinsic enzymes. Objective To evaluate the effect of chlorhexidine and sodium hypochlorite treatment on bond strength to dentin. Material and method Thirty bovine roots were randomly distributed into 3 groups (n=10): a) Control, b) 2% Chlorhexidine, and c) 5% Sodium Hypochlorite. Next, RelyX® ARC resin cement was used to cement the post. Each specimen resulted in samples from the three root thirds that were submitted to the pushout test (MPa) at 24 hours and 12 months. Bond strength values were analysed using the Kolmogorov-Smirnov, 3-way ANOVA and Tukey tests. The fracture mode of the pin was also analysed using stereomicroscopy. Result There were no significant differences between treatments at the immediate time (p=0.0644) or in the interaction of factors (p=0.1935). After one year, the experimental groups showed no significant differences in bond strength in relation to the control group, with the exception of the cervical third of the chlorohexidine group in which there was a significant loss of adhesion. As for the fracture mode, there was a predominance of the mixed type in all groups and thirds. Conclusion The use of chlorhexidine or hypochlorite provides neither benefits nor losses in the adhesive bond strength of fiberglass posts. However, there is an influence of the root thirds, with the worst bond strength in the apical third.


Resumo Introdução A fixação de pinos de fibra de vidro é realizada através de um processo adesivo. Falhas podem ocorrer na adesão devido à degradação hidrolítica dos adesivos, ou pela degradação das fibras colágenas da camada híbrida por enzimas intrínsecas. Objetivo Avaliar o efeito do tratamento com clorexidina e hipoclorito de sódio sobre a resistência de união adesiva à dentina. Material e método Trinta raízes bovinas foram distribuídas aleatoriamente em 3 grupos (n=10): a) Controle, b) Clorexidina 2% e c) Hipoclorito de Sódio 5%. Após, para a cimentação do pino radicular, utilizou-se o cimento resinoso RelyX® ARC. Cada espécime resultou corpos-de-prova dos três terços radiculares, os quais foram submetidos ao teste de pushout (MPa) nos períodos de 24 horas e 12 meses. Valores de resistência de união foram analisados pelos testes de Kolmogorov-Smirnov, ANOVA (three-way) e de Tukey. Analisou-se ainda o modo de fratura do pino, através de estereomicroscopia. Resultado Não houve diferenças significativas entre tratamento no tempo imediato (p=0,0644) ou na interação dos fatores (p=0,1935). Após um ano, os grupos experimentais não promoveram diferença significante na resistência de união em relação ao controle, com exceção do terço cervical do grupo clorexidina, onde houve uma perda significativa de adesão. Quanto ao modo de fratura, houve predominância do tipo mista em todos os grupos e terços. Conclusão O uso de clorexidina ou hipoclorito não promove benefícios ou prejuízos na resistência de união adesiva de pinos de fibra, mas há influência dos terços radiculares, sendo a pior resistência de união no terço apical.


Subject(s)
Sodium Hypochlorite , In Vitro Techniques , Chlorhexidine , Cementation , Dental Pins , Resin Cements , Dental Pulp Cavity , Dentin
18.
Rev. odontol. UNESP (Online) ; 48: e20190052, 2019. tab, graf
Article in Portuguese | LILACS (Americas), BBO | ID: biblio-1043172

ABSTRACT

Resumo Introdução Dentes artificiais têm sido empregados para a prática de ensino pré-clínico. Porém, não se sabe o comportamento dos mesmos frente aos diferentes procedimentos realizados durante um tratamento endodôntico simulado. Objetivo Avaliar a microdureza de réplicas de dentes humanos, frente a diferentes soluções irrigadoras. Material e método Quarenta e cinco incisivos centrais superiores artificiais de três marcas comerciais nacionais (dentes "A", "B" e "C") e 15 incisivos humanos foram utilizados. As amostras foram seccionadas a 5 mm do ápice dentário. Os fragmentos radiculares foram fixados em resina para posterior teste de microdureza. Os ensaios da microdureza Knoop foram realizados em dois momentos: momento 1 - microdureza inicial; momento 2 - microdureza final, que foi feita após o uso das soluções irrigadoras (Cloreto de Sódio a 0,9%, Hipoclorito de Sódio a 2,5% e Gluconato de Clorexidina a 2%). As endentações deixadas na superfície da amostra foram mensuradas. O valor obtido para microdureza de cada amostra foi feita com base na média de três endentações. Para análise estatística, foram utilizados os testes ANOVA e Teste t pareado, com nível de significância de 5%. Resultado Os dentes artificiais "A" e "C" apresentaram valores inferiores de microdureza quando comparados ao dente humano (P = 0,05). Não houve diferença estatística entre os dentes artificiais "B" e o dente humano (P = 0,2428). Quanto ao uso das diferentes soluções irrigadoras, também não houve diferença na microdureza das peças dentárias. Conclusão Embora a solução irrigadora não tenha influenciado a microdureza, os dentes artificiais apresentaram valores de dureza inferiores aos do dente humano.


Abstract Introduction Artificial teeth have been used for preclinical teaching practice. However, the behavior of the same is not known in relation to the different procedures performed during a simulated endodontic treatment. Objective To evaluate the microhardness of replicates of human teeth, in front of different irrigating solutions. Material and method Forty-five artificial upper central incisors of three national trade marks (teeth "A", "B" and "C") and fifteen human incisors were used. Samples were sectioned 5 mm from the apex. The root fragments were fixed in resin for later microhardness test. The Knoop microhardness tests were performed in two moments: moment 1 - initial microhardness; moment 2 - final microhardness, which was done after the use of the irrigating solutions (0.9% sodium chloride, 2.5% sodium hypochlorite and 2% chlorhexidine gluconate). The indentations left on the sample surface were measured. The obtained value for microhardness of each sample was made based on the average of three indentations. ANOVA and Paired t-test were used for statistical analysis. Significance level of 5%. Result Artificial teeth "A" and "C" presented lower values ​​of microhardness when compared to human teeth (P = 0.05). There was no statistical difference between the artificial teeth "B" for the human (P = 0.2428). Regarding the use of different irrigation solutions, there was also no difference in the microhardness of dental pieces. Conclusion Although the irrigating solution did not influence the microhardness, the artificial teeth presented values ​​of hardness inferior to the human tooth.


Subject(s)
Sodium Hypochlorite , Tooth, Artificial , Sodium Chloride , Chlorhexidine , Hardness Tests , Education, Dental , Endodontics
19.
Rev. odontol. UNESP (Online) ; 48: e20180130, 2019. tab
Article in English | LILACS (Americas), BBO | ID: biblio-1004375

ABSTRACT

Abstract Introduction Much advertising in mouthwash is conveyed in all media appealing to the anti-plaque effect and rendering a disservice to the community. Mouth rinses are available over-the-count and differ on their compositions and antimicrobial effectiveness. Objective In this study, we evaluated the antimicrobial activity of 35 widely available mouth rinses against bacterial species involved in initiation of dental biofilm - Streptococcus gordonii, Streptococcus mitis, Streptococcus oralis, Streptococcus salivarius, and Streptococcus sanguinis. Material and method The Minimum Inhibitory Concentration (MIC) and the Minimum Bactericidal Concentration (MBC) of the evaluated mouth rinses were determined according to the Clinical & Laboratory Standards Institute protocols. Data were submitted to Kruskal-Wallis test and Mann-Whitney post hoc (α=0.05). Result About 70% of the mouth rinses achieved high antibacterial activity and 30%, a low antibacterial activity against all the species tested. The most ineffective mouth rinse showed antibacterial activity (MIC) at 1:1 dilution, while the most effective showed activity even at 1:2048 dilution, which may imply prolonged effect in the mouth. About 51% of mouth rinses showed bactericidal activity, and it was verified that cetylpyridinium chloride or chlorhexidine digluconate containing in the formulation were associated with the highest activity. Conclusion Most - but not all - mouth rinses commercially available are effective in inhibiting in vitro initial colonizers of dental surfaces.


Resumo Introdução Muita publicidade sobre enxaguatórios bucais é veiculada em todos os meios de comunicação apelando para o efeito anti-placa e prestando um desserviço à comunidade. Grande quantidade de enxaguatórios bucais está disponível no mercado e estes diferem em suas composições e eficácia antimicrobiana. Objetivo Neste estudo, avaliamos a atividade antimicrobiana de 35 enxaguatórios bucais amplamente disponíveis contra espécies bacterianas envolvidas na iniciação do biofilme dental - Streptococcus gordonii, Streptococcus mitis, Streptococcus oralis, Streptococcus salivarius e Streptococcus sanguinis. Material e método A Concentração Inibitória Mínima (CIM) e a Concentração Bactericida Mínima (CBM) dos enxaguatórios avaliados foram determinadas de acordo com os protocolos do Clinical & Laboratory Standards Institute. Os dados foram submetidos ao teste Kruskal-Wallis e Mann-Whitney post hoc (α=0,05). Resultado Aproximadamente 70% dos enxaguatórios bucais alcançaram alta atividade antibacteriana e 30%, baixa atividade antibacteriana contra todas as espécies testadas. O enxaguatório bucal mais ineficaz mostrou atividade antibacteriana (CIM) na diluição de 1:1, enquanto a mais eficaz mostrou atividade mesmo na diluição de 1:2048, o que pode implicar em efeito prolongado na boca. Cerca de 51% dos enxaguatórios bucais apresentaram atividade bactericida, e verificou-se que formulações contendo cloreto de cetilpiridíneo ou digluconato de clorexidina estavam associados à maior atividade. Conclusão A maior parte - mas não todos - dos enxaguatórios bucais comercialmente disponíveis são eficazes na inibição de colonizadores iniciais de superfícies dentárias in vitro.


Subject(s)
Bacteria , Efficacy , Dentition , Mouthwashes , Sodium Fluoride , In Vitro Techniques , Cetylpyridinium , Chlorhexidine , Biofilms , Streptococcus oralis , Streptococcus mitis , Streptococcus gordonii , Streptococcus salivarius , Anti-Bacterial Agents
20.
Rev. Salusvita (Online) ; 38(4): 1127-1149, 2019.
Article in Portuguese | LILACS (Americas) | ID: biblio-1117870

ABSTRACT

Introdução: A adesão da resina composta à dentina ocorre pela formação da camada híbrida. Assim, sua degradação ocasiona a perda da resistência de união na interface resina/dentina, influenciando na longevidade da restauração. Após o condicionamento ácido e aplicação do sistema adesivo na dentina desmineralizada, fibras colágenas não envolvidas por sistema adesivo ficam desprotegidas e suscetíveis ao ataque das metaloproteinases (MMPs). Objetivos: Esta revisão buscou esclarecer o efeito das MMPs na degradação da camada híbrida e os efeitos da clorexidina no processo de adesão. Materiais e métodos: Foi realizada uma revisão da literatura por meio de uma busca bibliográfica nas bases de dados Pubmed/ Medline, Scielo e Google Acadêmico, utilizados estudos publicados nos anos de 2005 a 2018. Foi realizada a busca pelos seguintes descritores: Dentistry, MMPs, Chlorhexidine. Resultados: Estas enzimas, presentes na própria dentina, são reativadas pelo ácido fosfórico ou pelos monômeros ácidos dos adesivos autocondicionantes e iniciam a degradação. A aplicação da clorexidina (CHX) na dentina, após o condicionamento ácido, impede ou retarda a degradação das fibras de colágeno da camada híbrida. Conclusão: Concluiu-se que a ligação adesiva à dentina diminui com o passar dos anos devido à ação das MMPs que degradam o colágeno não infiltrado por monômeros adesivos na parte mais profunda da camada híbrida. Além disso, a clorexidina como inibidor terapêutico em sistemas adesivos convencionais é capaz de inibir as MMPs e assim a ligação adesiva à dentina pode ser mantida estável por um período de tempo mais longo.


Introduction: The adhesion of the composite resin to the dentin occurs by the formation of the hybrid layer. Thus, its degradation causes loss of union resistance on interface resin / dentin interface, directly influencing the longevity of the restoration. After the acid etching and the application of the adhesive system into demineralized dentin, collagen fibers not involved by adhesive system get unprotected and susceptibles to attack by metalloproteinases (MMPs). The enzymes, present in the dentin itself, are rehabilitated by phosphoric acid or by the acids monomers of the self-etching adhesives initiating degradation. The application of chlorhexidine (CHX) in the dentin, after acid conditioning, prevents or slows down the degradation of the collagen fibers of the hybrid layer. This literature review sought to clarify the effect of MMPs on the degradation of the hybrid layer and the effects of chlorhexidine on the adhesion process. It was concluded that the adhesive bonding to dentin decreases with the passage of years due in part to the action of MMPs, which degrade collagen not infiltrated by adhesive monomers in the deepest part of the hybrid layer. In addition, the use of chlorhexidine as a therapeutic inhibitor in conventional adhesive systems is capable of inhibiting the MMPs and thus the adhesive bonding to the dentin can be kept stable for a longer period of time.


Subject(s)
Matrix Metalloproteinases , Chlorhexidine
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