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1.
Rev. colomb. cir ; 39(2): 254-259, 20240220. tab
Article in Spanish | LILACS | ID: biblio-1532610

ABSTRACT

Introducción. El cáncer de vesícula biliar es una de las neoplasias más frecuentes de la vía biliar y la mayoría de los casos se diagnostican de forma incidental o en estadios avanzados. En Colombia existen pocas publicaciones acerca de la prevalencia y características clínicas de pacientes con cáncer insospechado de vesícula biliar. El objetivo de este trabajo fue actualizar la información existente. Métodos. Estudio de tipo transversal basado en registros médicos. Como variable de resultado se definió el hallazgo incidental de patología maligna reportado por un patólogo y el subtipo histológico. Se midieron variables demográficas, clínicas y quirúrgicas. Se calcularon OR con sus respectivos intervalos de confianza (IC95%). Resultados. De los 2630 casos analizados, en cuatro se hizo diagnóstico de cáncer incidental de vesícula, con una prevalencia del 0,15 %. Se encontraron como características asociadas al cáncer incidental de vesícula, la edad, el antecedente de cáncer y la presencia de pólipos. Conclusiones. Esta es una patología poco frecuente en la población evaluada, lo que permite afirmar que no es necesario realizar estudios prequirúrgicos más amplios de forma rutinaria, a menos que el paciente presente alguno de los factores asociados.


Introduction. Gallbladder cancer is one of the most common neoplasms of the bile duct and most cases are diagnosed incidentally or in advanced stages. In Colombia, there are few publications about the prevalence and clinical characteristics of patients with unsuspected gallbladder cancer. The objective of this work was to update the existing information. Methods. Cross-sectional study based on medical records. The incidental finding of malignant pathology reported and the histological subtype were defined as the outcome variable. Demographic, clinical and surgical variables were measured. ORs were calculated with their respective 95% CI. Results. Of the 2630 cases analyzed, four were diagnosed with incidental gallbladder cancer, with a prevalence of 0.15%. Characteristics associated with incidental gallbladder cancer were age, history of cancer and the presence of polyps. Conclusions. This is a rare pathology in the population evaluated, which allows us to recommend that it is not necessary to routinely perform more extensive presurgical studies, unless the patient presents any of the associated factors.


Subject(s)
Humans , Cholecystectomy , Gallbladder , Neoplasms , Polyps , Prevalence , Incidental Findings
2.
Rev. colomb. cir ; 38(2): 313-322, 20230303. fig, tab
Article in Spanish | LILACS | ID: biblio-1425204

ABSTRACT

Introducción. El síndrome post-colecistectomía fue descrito hace más de 70 años y se define como la presencia de síntomas gastrointestinales que pueden persistir después de la colecistectomía o aparecer como nuevos síntomas. Este síndrome, poco conocido, puede manifestarse desde pocos meses hasta varios años luego de la cirugía y ocurre entre 5 % y 40 % de los pacientes. Método. Estudio de cohorte prospectiva, que incluyó pacientes a quienes se les realizó colecistectomía laparoscópica en tres unidades quirúrgicas de Bogotá, D.C., Colombia, durante un período de ocho meses, con seguimientos periódicos durante dos años. El síndrome post-colecistectomía se definió como la presencia de al menos un síntoma gastrointestinal a partir del primer mes de la cirugía. Resultados. Se incluyeron 380 pacientes de los cuales 183 (48,2 %) desarrollaron el síndrome. La edad tuvo diferencia estadísticamente significativa entre aquellos que lo desarrollaron y los que no (p=0,024). La diarrea fue el único síntoma preoperatorio asociado al desarrollo del síndrome. El síndrome post-colecistectomía se encontró en el 42,1 % de los pacientes al primer mes de seguimiento y en el 17,4 % al segundo año. Conclusiones. El síndrome post-colecistectomía ocurre en un porcentaje importante de pacientes. En concordancia con la literatura, se encontró que la diarrea prequirúrgica es un factor de riesgo independiente para el desarrollo del síndrome. Se recomienda un adecuado seguimiento de los pacientes después de una colecistectomía


Introduction. Post-cholecystectomy syndrome (PCS) was described more than 70 years ago and is defined as the presence of gastrointestinal (GI) symptoms that may persist after cholecystectomy or can present as new symptoms. This little-known syndrome can appear from a few months to several years after surgery and occurs between 5% and 40% of patients. Method. Prospective cohort study, which included patients who underwent laparoscopic cholecystectomy in three surgical units in Bogotá, Colombia, during a period of eight months, with periodic follow-up for two years. PCS was defined as the presence of at least one GI symptom from the first month after surgery. Results. Three-hundred and eighty patients were included, of which 183 (48.2%) developed the syndrome. Age had a statistically significant difference between those who developed PCS and those who did not (p=0.024). Diarrhea was the only preoperative symptom associated with the development of PCS. Post-cholecystectomy syndrome was found in 42.1% at the first month of follow-up and in 17.4% at the second year. Conclusions. Post-cholecystectomy syndrome occurs in a significant percentage of patients. Consistent with the literature, preoperative diarrhea was found to be an independent risk factor for the development of the syndrome. Adequate follow-up of patients after cholecystectomy is recommended


Subject(s)
Humans , Abdominal Pain , Postcholecystectomy Syndrome , General Surgery , Cholecystectomy , Diarrhea
3.
Rev. méd. (La Paz) ; 29(1): 27-32, 2023. Tab
Article in Spanish | LILACS | ID: biblio-1450161

ABSTRACT

La colecistectomía laparoscópica es el estándar de oro para el tratamiento de la litiasis vesicular. El presente estudio tiene por objetivo difundir la experiencia de 10 años en colecistectomía laparoscópica del Hospital Municipal Los Pinos de La Paz, Bolivia. Se realizó la revisión de historias clínicas de pacientes internados y sometidos a colecistectomía laparoscópica de junio 2012 a julio 2022, la serie de casos estuvo compuesta por 1095 pacientes; 866 (79.3%) mujeres y 229 (20.7%) varones; el grupo etáreo con mayor casuística fue 31 a 40 años con 256 casos (23.3%), la edad promedio fue de 50,5 (10 a 81 años). La vía de ingreso de los pacientes fue por consulta externa 72.5% y emergencias 27.4%. El tiempo operatorio promedio fue de 85 min. (20 a 150 min.). El diagnostico de ingreso de mayor prevalencia fue la colecistitis crónica litiasica con 766 (69.9%). El factor de conversión a cirugía abierta fue la falta de identificación de estructuras anatómicas, con un índice de conversión de 6.9%. La estancia postoperatoria promedio fue de 3.5 días (1 a 6 días). Basado en los resultados obtenidos la colecistectomía laparoscópica demuestra ser aun el tratamiento seguro y efectivo en pacientes con colelitiasis.


Laparoscopic cholecystectomy is the Gold standard for the treatment of vesicular lithiasis. The present study aims to describe the experience in laparoscopic cholecystectomy of 10 years at Los Pinos Municipal Hospital in La Paz, Bolivia. A review of medical records of hospitalized patients undergoing laparoscopic cholecystectomy from June 2012 to July 2022 was carried out. Case series were 1095 patients; 866 (79.3%) female and 229 (20.7%) male; the age group with higher casuistry was 31 to 40 years (256 cases, 23.3%), the average age was 50.5 (10 to 81 years). The admission of patients was by outpatient 72.5% and emergency unit 27.4%. The average surgery time was 85 min. (20 to 150 min.). The highest prevalence diagnosis at admission was chronic lithiasic cholecystitis (766 cases, 69.9%). The conversion factor to open surgery was the anatomical structures identification difficulty, conversion rate of 6.9 %. The postoperative hospital stay average was 3.5 days (1 to 6 days). Based on the results obtained, laparoscopic cholecystectomy still proves to be the safe and effective treatment in patients with cholelithiasis.


Subject(s)
Cholecystectomy
4.
Article in Portuguese | LILACS, BDENF | ID: biblio-1451698

ABSTRACT

Objetivo: Validar um protocolo de teleconsulta pré-operatória de enfermagem em hernioplastia e colecistectomia. Método: Estudo metodológico realizado em um hospital filantrópico localizado em Rio Branco, Acre. Participaram dez enfermeiros especialistas em assistência perioperatória. A validação ocorreu no período de agosto a outubro de 2021. O protocolo do estudo foi fundamentado na revisão de escopo do Instituto Joanna Briggs (JBI) e nos diagnósticos e nas intervenções de enfermagem de ansiedade e o risco de recuperação cirúrgica retardada. Os dados foram analisados pelo índice de validade de conteúdo, adotando o valor maior ou igual a 0,8 na análise global. Resultados: Os enfermeiros validaram o conteúdo proposto, atestando sua abrangência, clareza e relevância em todos os itens, com altos índices de validade de conteúdo globais maiores que 0,95. Conclusão: O protocolo construído foi validado por especialistas, sendo evidenciadas sua abrangência, clareza e relevância de sua tecnologia didática instrucional para aplicabilidade clínica no período pré-operatório


Objective: To validate a preoperative nursing teleconsultation protocol for hernioplasty and cholecystectomy. Method: This is a methodological study carried out at a philanthropic hospital located in the city of Rio Branco, state of Acre, Brazil. Ten nurses specialized in perioperative care participated in the study. The validation took place from August to October 2021. The study protocol was based on the scoping review by the Joanna Briggs Institute ( JBI) and on nursing diagnoses and interventions for anxiety and the risk of delayed surgical recovery. Data were analyzed using the content validity index, adopting a value greater than or equal to 0.8 in the overall analysis. Results: The nurses validated the proposed content, attesting to its comprehensive-ness, clarity, and relevance in all items, with high overall content validity indices greater than 0.95. Conclusions: The developed protocol was validated by experts, showing the comprehensiveness, clarity, and relevance of its instructional didactic technology for clinical applicability in the preoperative period


Subject(s)
Humans , Perioperative Nursing , Cholecystectomy/nursing , Remote Consultation/methods , Herniorrhaphy/nursing , Clinical Protocols
5.
Chinese Medical Journal ; (24): 1680-1689, 2023.
Article in English | WPRIM | ID: wpr-980933

ABSTRACT

BACKGROUND@#Textbook outcome (TO) can guide decision-making among patients and clinicians during preoperative patient selection and postoperative quality improvement. We explored the factors associated with achieving a TO for gallbladder carcinoma (GBC) after curative-intent resection and analyzed the effect of adjuvant chemotherapy (ACT) on TO and non-TO patients.@*METHODS@#A total of 540 patients who underwent curative-intent resection for GBC at the Department of Hepatobiliary Surgery of the First Affiliated Hospital of Xi'an Jiaotong University from January 2011 to December 2020 were retrospectively analyzed. Multivariable logistic regression was used to investigate the factors associated with TO.@*RESULTS@#Among 540 patients with GBC who underwent curative-intent resection, 223 patients (41.3%) achieved a TO. The incidence of TO ranged from 19.0% to 51.0% across the study period, with a slightly increasing trend over the study period. The multivariate analysis showed that non-TO was an independent risk factor for prognosis among GBC patients after resection ( P = 0.003). Age ≤60 years ( P = 0.016), total bilirubin (TBIL) level ≤34.1 μmol/L ( P <0.001), well-differentiated tumor ( P = 0.008), no liver involvement ( P <0.001), and T1-2 stage disease ( P = 0.006) were independently associated with achieving a TO for GBC after resection. Before and after propensity score matching (PSM), the overall survival outcomes of non-TO GBC patients who received ACT and those who did not were statistically significant; ACT improved the prognosis of patients in the non-TO group ( P <0.05).@*CONCLUSION@#Achieving a TO is associated with a better long-term prognosis among GBC patients after curative-intent resection, and ACT can improve the prognosis of those with non-TO.


Subject(s)
Humans , Middle Aged , Gallbladder Neoplasms/pathology , Retrospective Studies , Prognosis , Hepatectomy , Cholecystectomy
6.
Chinese Medical Journal ; (24): 840-847, 2023.
Article in English | WPRIM | ID: wpr-980869

ABSTRACT

BACKGROUND@#Cholecystectomy is a standard surgery for patients suffering from gallbladder diseases, while the causal effects of cholecystectomy on colorectal cancer (CRC) and other complications are still unknown.@*METHODS@#We obtained genetic variants associated with cholecystectomy at a genome-wide significant level ( P value <5 × 10 -8 ) as instrumental variables (IVs) and performed Mendelian randomization (MR) to identify the complications of cholecystectomy. Furthermore, the cholelithiasis was also treated as the exposure to compare its causal effects to those of cholecystectomy, and multivariable MR analysis was carried out to judge whether the effect of cholecystectomy was independent of cholelithiasis. The study was reported based on Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization guidelines.@*RESULTS@#The selected IVs explained 1.76% variance of cholecystectomy. Our MR analysis suggested that cholecystectomy cannot elevate the risk of CRC (odds ratio [OR] =1.543, 95% confidence interval [CI]: 0.607-3.924). Also, it was not significant in either colon or rectum cancer. Intriguingly, cholecystectomy might decrease the risk of Crohn's disease (OR = 0.078, 95% CI: 0.016-0.368) and coronary heart disease (OR = 0.352, 95% CI: 0.164-0.756). However, it might increase the risk of irritable bowel syndrome (IBS) (OR = 7.573, 95% CI: 1.096-52.318). Cholelithiasis could increase the risk of CRC in the largest population (OR = 1.041, 95% CI: 1.010-1.073). The multivariable MR analysis suggested that genetic liability to cholelithiasis could increase the risk of CRC in the largest population (OR = 1.061, 95% CI: 1.002-1.125) after adjustment of cholecystectomy.@*CONCLUSIONS@#The study indicated that cholecystectomy might not increase the risk of CRC, but such a conclusion needs further proving by clinical equivalence. Additionally, it might increase the risk of IBS, which should be paid attention to in clinical practice.


Subject(s)
Humans , Mendelian Randomization Analysis , Irritable Bowel Syndrome , Colorectal Neoplasms/genetics , Cholelithiasis/complications , Cholecystectomy/adverse effects , Genome-Wide Association Study , Polymorphism, Single Nucleotide
7.
Rev. cuba. cir ; 61(4)dic. 2022.
Article in Spanish | LILACS, CUMED | ID: biblio-1441532

ABSTRACT

Introducción: La incidencia de fístula colecistocutánea ha disminuido debido al abordaje quirúrgico precoz de los pacientes con litiasis vesicular. Objetivo: Presentar un caso de fístula colecistocutánea secundaria a colecistopatía litiásica crónica. Caso clínico: Paciente femenina de 87 años de edad que fue atendida en los servicios de urgencia de cirugía luego de haber sufrido, 2 semanas antes, dolor en hipocondrio derecho acompañado de aumento de volumen progresivo de dicha región. Al examen físico se constató secreción espontánea de bilis oscura de carácter continuo por orificio fistuloso. Se decide llevar al salón de operaciones y se le realizó colecistectomía de cuello a fondo y colangiografía transcística visualizándose litos. Se procedió a realizar coledocotomía, extracción de cálculos con lavado de la vía biliar y se colocó sonda en T. La evolución fue satisfactoria. Conclusiones: El tratamiento combinado de cirugía y antibioterapia es curativo(AU)


Introduction: The incidence of cholecystocutaneous fistula has decreased due to the early surgical managment of patients with vesicular lithiasis. Objective: To present a case of cholecystocutaneous fistula secondary to chronic lithiasic cholecystopathy. Clinical case: An 87-year-old female patient was attended in the emergency surgical services after having suffered, two weeks earlier, pain in the right hypochondrium accompanied by progressive increase in volume in that region. Physical examination revealed spontaneous discharge of dark bile continuously through a fistulous orifice. The patient was decided to be taken to the operating room, where she was performed a profound infundibulum cholecystectomy and transcystic cholangiography, lithiasis being visualized. The next considered step was choledochotomy for stone extraction with bile duct lavage, and a T-tube was placed. Evolution was satisfactory. Conclusions: The treatment combining surgery and antibiotic therapy is curative(AU)


Subject(s)
Humans , Female , Aged, 80 and over , Cholecystectomy/methods , Lithiasis/surgery , Fistula/epidemiology , Cholangiography/methods
8.
Rev. cuba. cir ; 61(4)dic. 2022.
Article in Spanish | LILACS, CUMED | ID: biblio-1441530

ABSTRACT

Introducción: Con el advenimiento de la pandemia por la enfermedad de la COVID-19 ha sido necesario reorganizar los servicios de salud y modificar en cierta medida la indicación quirúrgica en la colecistitis aguda. Objetivo: Caracterizar la colecistostomía como una alternativa segura y eficaz para la resolución de la colecistitis aguda litiásica en pacientes en los que no está indicada la cirugía, portador o no de la COVID-19. Métodos: Se realizó una revisión descriptiva narrativa desde el 2019 hasta el 2021 de las fuentes primarias y secundarias que abordan este tema; fue este período de tiempo en el que se desarrolló la pandemia provocada por SARS-Cov 2. Se usaron el Google Chrome y las bases de datos electrónicas MEDLINE/PubMed, INDEXMEDICUS y fuentes de información en revistas basadas en evidencias como ACP Journal Best Evidence y Cochrane. Desarrollo: El impacto de la crisis sanitaria sobre los servicios quirúrgicos se traduce en la cancelación de las colecistectomías electivas en el 97,6 por ciento de los centros. Esta decisión no es inocua, puesto que se ha estimado un riesgo anual de desarrollar complicaciones del 1-3 por ciento en la colelitiasis sintomática. Conclusiones: La colecistostomía es el método más acertado a utilizar para la resolución de la colecistitis aguda litiásica en pacientes en los que no está indicada la cirugía, con mala respuesta al tratamiento médico y sin tener la completa seguridad de que el paciente es o no portador de la COVID-19(AU)


Introduction: With the arrival of the COVID-19 pandemic, to reorganize health services has been necessary, as well as to modify, to a certain extent, the surgical indication for acute cholecystitis. Objective: To characterize cholecystostomy as a safe and effective alternative for the resolution of acute lithiasic cholecystitis in patients with no surgical indication, whether or not they have COVID-19. Methods: A narrative-descriptive review was carried out from 2019 to 2021 of primary and secondary sources addressing this topic; this time period marked the development of the pandemic caused by SARS-CoV-2. Google Chrome was used, together with the electronic databases MEDLINE/PubMed and INDEXMEDICUS, as well as sources of information in evidence-based journals, such as ACP Journal Best Evidence and Cochrane. Development: The impact of the health crisis over surgical services is translated into the cancellation of elective cholecystectomies in 97.6 percent of the centers. This decision is not innocuous, since an annual risk of developing complications has been estimated at 1-3 percent for symptomatic cholelithiasis. Conclusions: Cholecystostomy is the most successful method to be used for the resolution of acute lithiasic cholecystitis in patients with no surgical indication or poor response to medical treatment, without complete certainty as to whether or not the patient has COVID-19(AU)


Subject(s)
Humans , Cholecystectomy/methods , Cholecystitis, Acute/etiology , COVID-19/epidemiology , Epidemiology, Descriptive
9.
Rev. cuba. cir ; 61(4)dic. 2022.
Article in Spanish | LILACS, CUMED | ID: biblio-1441524

ABSTRACT

Introducción: Las lesiones iatrogénicas de las vías biliares representan una complicación quirúrgica grave de la colecistectomía. Objetivo: Determinar la morbilidad de las lesiones de la vía biliar en el servicio de cirugía del Hospital Universitario "Manuel Ascunce Domenech". Métodos: Se realizó un estudio descriptivo, prospectivo y observacional de pacientes que ingresaron en el servicio de cirugía del Hospital Universitario "Manuel Ascunce Domenech" con diagnóstico de lesión de la vía biliar, desde septiembre del 2018 hasta enero del 2022. El universo estuvo conformado por 12 pacientes que cumplieron con los criterios de inclusión. Se utilizaron métodos estadísticos descriptivos y cálculos con valores porcentuales. Resultados: La mayor incidencia de los pacientes fue del sexo femenino y de piel blanca, con un 61,4 por ciento y 85,7 por ciento, respectivamente. Predom inó el tipo de cirugía convencional y diagnóstico intraoperatorio con un 66,7 por ciento y 50 por ciento, respectivamente. El tipo E1 y E2 de la clasificación de Strasberg y la hepaticoyeyunostomía fue la operación con mayor frecuencia con un 66,7 por ciento. La bilirragia fue la complicación que predominó con el 70 por ciento. Conclusiones: La mayoría de los pacientes son del sexo femenino y de piel blanca, donde la cirugía convencional y el diagnóstico intraoperatorio son los hallazgos más frecuentes. Más de la mitad de los pacientes son clasificados como tipo E1 y tipo E2 según clasificación de Strasberg. La hepaticoyeyunostomía en Y de Roux y en asa de Braum transmesocólica es el proceder realizado en casi la totalidad de los pacientes. La fuga biliar es la complicación más frecuente(AU(


Introduction: Iatrogenic bile duct lesions represent a serious surgical complication of cholecystectomy. Objective: To determine the morbility of bile duct lesions in the surgical service of Hospital Universitario "Manuel Ascunce Domenech". Methods: A descriptive, prospective and observational study was carried out with patients admitted to the surgery service of Hospital Universitario "Manuel Ascunce Domenech" with a diagnosis of bile duct lesion, from September 2018 to January 2022. The study universe consisted of twelve patients who met the inclusion criteria. Descriptive statistical methods and calculations with percentage values were used. Results: The highest incidence of patients corresponded to the female sex and the white skin, accounting for 61.4 percent and 85.7(Percent(, respectively. Conventional surgery and intraoperative diagnosis predominated, accounting for 66.7 % and 50 %, respectively. Types E1 and E2 according to the Strasberg classification, together with hepaticojejunostomy, was the most frequent surgery type, accounting for 66.7 %. Biliary bleeding was the predominant complication, accounting for 70 %. Conclusions: Most of the patients belong to the female sex and have white skin, in which cases conventional surgery and intraoperative diagnosis are the most frequent findings. More than half of the patients are classified as types E1 or E2 according to the Strasberg classification. Transmesocolic Braun loop and Roux-en-Y hepaticojejunostomy is the procedure performed in almost all patients. Biliary leakage is the most frequent complication(AU)


Subject(s)
Humans , Female , Bile Ducts/injuries , Cholecystectomy/methods , Morbidity , Epidemiology, Descriptive , Prospective Studies , Observational Study
10.
Cambios rev med ; 21(2): 886, 30 Diciembre 2022. tabs, grafs.
Article in Spanish | LILACS | ID: biblio-1416079

ABSTRACT

INTRODUCCIÓN. El cáncer de colon es una neoplasia del tubo digestivo considerada una de las más frecuentes en ambos sexos y que predomina en adultos mayores. OBJETIVO. Describir las características clínicas y epidemiológicas de los pacientes con cáncer de colon. MATERIALES Y MÉTODOS. Estudio observacional, descriptivo, retrospectivo. Población de 1 601 y muestra de 210 datos de Historias Clínicas Electrónicas de pacientes diagnosticados con cáncer de colon, atendidos por la Unidad de Oncología del Hospital de Especialidades Carlos Andrade Marín de la ciudad de Quito en el periodo enero de 2016 a diciembre de 2019. Criterios de inclusión: diagnóstico confirmado de Cáncer de Colon, edad igual o mayor a 18 años, y disponer de todos los datos clínicos requeridos en el estudio. Se utilizó el método de muestreo probabilístico con lo que se estimó una proporción para el estudio con un intervalo de confianza del 95%, un margen de error del 5% y una frecuencia esperada del 3%, de donde se obtuvo una muestra ajustada al 10% de pérdidas. El procesamiento de datos se realizó en los programas Microsoft Excel versión 16 y el Statistical Package for Social Sciences versión 24. RESULTADOS. La mayor presentación fue en adultos mayores de 50 años, con una relación 1:1 en cuanto a sexo, y en la procedencia, se ubicó mayoritariamente en la población de la región Sierra; las personas con una actividad económica de tipo profesional fueron las más afectadas; en lo que se refiere a los antecedentes se encontró mayor relación en los personales y dentro de estos los pólipos; no hubo relación con los antecedentes quirúrgicos ni familiares. El síntoma de debut más prevalente fue el dolor abdominal; la mayoría fueron sometidos a colonoscopia; predominó la lateralidad derecha y el tipo histológico principalmente identificado fue el adenocarcinoma. CONCLUSIÓN. No se observó relación estadísticamente significante entre estadíos, evolución y tratamientos instaurados, lo que pudo estar influenciado por el muestreo al azar; y que el 53,30% de los pacientes aún se encuentra en controles.


INTRODUCTION. Colon cancer is a neoplasm of the digestive tract considered one of the most frequent in both sexes and predominantly in older adults. OBJECTIVE. To describe the clinical and epidemiological characteristics of patients with colon cancer. MATERIALS AND METHODS. Observational, descriptive, retrospective study. Population of 1 601 and sample of 210 data from Electronic Medical Records of patients diagnosed with colon cancer, attended by the Oncology Unit of the Hospital de Especialidades Carlos Andrade Marín of the city of Quito in the period January 2016 to December 2019. Inclusion criteria: confirmed diagnosis of Colon Cancer, age equal to or older than 18 years, and having all the clinical data required in the study. The probability sampling method was used with which a proportion was estimated for the study with a confidence interval of 95%, a margin of error of 5% and an expected frequency of 3%, from which a 10% loss adjusted sample was obtained. Data processing was performed in Microsoft Excel version 16 and Statistical Package for Social Sciences version 24. The greatest presentation was in adults over 50 years of age, with a 1:1 ratio in terms of sex, and in terms of origin, it was mainly located in the population of the Sierra region; people with a professional economic activity were the most affected; in terms of history, a greater relationship was found in personal history and within these, polyps; there was no relationship with surgical or family history. The most prevalent debut symptom was abdominal pain; the majority underwent colonoscopy; right laterality predominated and the histological type mainly identified was adestatistically significant relationship was observed between stages, evolution and treatment, which could be influenced by random sampling; and that 53,30% of the patients are still in controls.


Subject(s)
Humans , Male , Female , Sigmoid Neoplasms , Colonic Polyps , Colon , Colonic Diseases , Colonic Neoplasms , Adenomatous Polyposis Coli , Cholecystectomy , Adenocarcinoma , Abdominal Pain , Colonoscopy , Colectomy , Ecuador , Gastrointestinal Hemorrhage , Intestinal Neoplasms , Medical Oncology
12.
Rev. med. Chile ; 150(9): 1131-1137, sept. 2022. tab, graf, ilus
Article in Spanish | LILACS | ID: biblio-1431886

ABSTRACT

BACKGROUND: Gallbladder Cancer (GBC) prevalence varies among countries, associated with different geographical and genetic factors. The Mapuche ethnicity (Ethnia mostly located between the VIII and X Chilean regions) stands out in Chile due to its high GBC prevalence. Aim: To estimate the GBC prevalence in patients undergoing cholecystectomy at a public hospital in the Northern region of Chile (Tarapaca), where other ethnical groups are common. MATERIAL AND METHODS: Pathological reports of 3270 patients (72% women) who underwent cholecystectomy between January 2016 and December 2019 were revised. Subsequently, the accreditation of ethnic belonging for each patient to one of the ten native communities in Chile was requested to the National Corporation for Native Communities Development (CONADI). RESULTS: According to the analysis of pathological reports, the global GBC prevalence was 0.3 %. The prevalence in Aymaras was 0.4% and 0% in Mapuches. The distribution of ethnic origins among analyzed patients was Aymara in 14.3, Mapuche in 2.7%, Diaguita in 1.7%, Quechua in 1.3%, Atacameña in 0.2%, and Colla in 0.2%. No specific ethnic origin was found in 79% of patients. Conclusions: There was a low GBC prevalence rate in Northern Chile and among the Aymara population.


Subject(s)
Humans , Male , Female , Gallbladder Neoplasms/epidemiology , Cholecystectomy , Ethnicity , Chile/epidemiology , Prevalence
13.
Rev. colomb. cir ; 37(4): 604-611, 20220906. tab
Article in Spanish | LILACS | ID: biblio-1396387

ABSTRACT

Introducción. Las infecciones del árbol biliar surgen principalmente por estasis asociada a colecistitis aguda, coledocolitiasis y colecistitis alitiásica, siendo pilar del tratamiento un drenaje apropiado y un régimen antibiótico eficaz. El objetivo de esta investigación fue caracterizar la flora bacteriana de los cultivos de bilis. Métodos. Se realizó un estudio observacional, descriptivo, de corte transversal y retrospectivo de pacientes llevados a colecistectomía, colangiopancreatografía retrograda endoscópica y colecistostomía en nuestra institución, a quienes se les tomó cultivo de líquido biliar entre 2017 - 2021. Resultados. Se incluyeron 119 pacientes intervenidos, de los cuales 55,4 % fueron mujeres y el promedio de edad fue de 63,1 (± 16). La clasificación Tokio 2 fue la más frecuente (55,4 %). El germen aislado con mayor frecuencia fue E. coli (51,2 %). El antibiótico más usado fue ampicilina más sulbactam (44,6 %) seguido de piperacilina tazobactam (40,3 %). Conclusión. La Escherichia coli es el germen aislado con mayor frecuencia en infecciones del árbol biliar. No hay claridad con respecto al uso de antimicrobianos de manera profiláctica en esta patología, por esto es conveniente generar protocolos para la toma de muestras y cultivos de bilis en esta población, con el fin de establecer la necesidad del uso de antibióticos y conocer los perfiles de resistencia bacteriana.


Introduction. Infections of the biliary tree arise mainly from stasis associated with acute cholecystitis, choledocholithiasis, and acalculous cholecystitis, with appropriate drainage and an effective antibiotic regimen being the mainstay of treatment. This research is proposed with the aim aim to characterize the bacterial flora of bile cultures.Methods. An observational, descriptive, cross-sectional and retrospective study of patients who underwent cholecystectomy, endoscopic retrograde cholangiopancreatography and cholecystostomy in our institution, whom bile fluid culture was taken between 2017 and 2021, was performed. Results. 119 operated patients were included, of which 55.4% were women, the average age was 63.1 (± 16). The TOKIO 2 classification was the most frequent with 55.4% of the patients. The most frequently isolated germ was E. coli with 51.2%. The most used antibiotic was ampicillin plus sulbactam with 44.6% prescription followed by piperacillin tazobactam with a prescription frequency of 40.3%.Conclusion. Escherichia coli is the most frequently isolated germ in infections of the biliary tree. There is no clarity regarding the use of antimicrobials prophylactically in this pathology. For this reason it is convenient to generate protocols for taking samples and bile cultures in this population, in order to establish the need for the use of antibiotics and to know the profiles of bacterial resistance.


Subject(s)
Humans , Cholecystectomy , Bacterial Load , Cholelithiasis , Cholecystitis , Anti-Bacterial Agents
14.
Rev. cir. (Impr.) ; 74(4): 432-437, ago. 2022. tab, graf
Article in Spanish | LILACS | ID: biblio-1407932

ABSTRACT

Resumen La colecistolitiasis es una condición común en Chile. La complicación más frecuente de esta condición es la colecistitis aguda. Aproximadamente 60.000 colecistectomías son realizadas anualmente en nuestro país, convirtiéndola en una de las patologías digestivas más frecuentes. El tratamiento de la colelitiasis ha evolucionado las últimas dos décadas. Con el desarrollo de la laparoscopía a final de 1980, la colecistectomía abierta fue definitivamente sustituida en los 90 por la vía laparoscópica. Desafortunadamente, la generalización de este procedimiento produjo un aumento en la incidencia de lesiones de vía biliar, aumentando desde una 0,1-0,2% hasta un 0,5-0,7%. Si bien, con el progresivo entrenamiento de los cirujanos en la cirugía mínimamente invasiva esta cifra ha disminuido nuevamente, la LVB aún constituye una de las complicaciones más graves en cirugía, generando gran impacto en la calidad de vida del paciente, e incluso costos en salud que pueden llegar a ser devastadores. El manejo de una lesión de vía biliar es, para muchos cirujanos, un desafío quirúrgico, que para su resolución requiere de las habilidades y experiencia de un cirujano hepatobiliar y derivación a centros de salud especializados. Sin duda, la acción más importante es extremar de manera rutinaria las medidas de prevención. Sin embargo, una vez que la lesión se ha producido, el futuro del paciente depende, directamente, del buen criterio del cirujano, tanto para realizar un diagnóstico temprano, como del enfrentamiento terapéutico que realice. El objetivo de este trabajo es dar a conocer diferentes conductas preventivas y terapéuticas cuando esta complicación se presenta.


Calculous biliary disease is a common condition in Chile. Over 60.000 cholecystectomies are performed annually, making gallstone disease one of the most common digestive health problems. The treatment of calculous biliary disease has evolved over the last 2 decades. With the development of laparoscopic technology in the late 1980s, new techniques for cholecystectomy were introduced. By the early 1990s, laparoscopic cholecystectomy had replaced open cholecystectomy in the operative management of gallbladder stone disease. Unfortunately, the widespread application of laparoscopic cholecystectomy has led to a concurrent rise in the incidence of major bile duct injuries. Reports have estimated the incidence has risen from 0.1-0.2 to 0.5-0.7%. Although, exponential training of surgeons in minimally invasive surgery has led to decrease this numbers again, bile duct injuries still constitute one of the most serious complications in surgery, generating a great impact on the patient's quality of life, and even health costs that can be devastating. The management of patients following major bile duct injurie is a surgical challenge, often requiring the skills of experienced hepatobiliary surgeons at tertiary referral centers. In this setting, the most important action is to routinely maximize prevention measures. However, once injury has occurred, patient's future depends directly on the correct judgment of the surgeon, both to make an early diagnosis and to choose the best therapeutic confrontation. The objective of this article is to present the different preventive and therapeutic options available when this complication occurs.


Subject(s)
Humans , Bile Duct Diseases , Cholecystectomy, Laparoscopic , Bile Ducts/diagnostic imaging , Magnetic Resonance Imaging , Cholangiography , Cholecystectomy , Risk Factors , Laparoscopy
15.
Rev. med. Chile ; 150(7): 861-867, jul. 2022. tab, graf
Article in Spanish | LILACS | ID: biblio-1424149

ABSTRACT

BACKGROUND: Bile duct reconstruction (BDR) secondary to bile duct injury during cholecystectomy (BDIC) is a complex surgery, and an important issue is the quality of life (QL) after the procedure. AIM: To compare the QL of a cohort of patients who underwent BDR due to BDIC with a cohort of patients who underwent a cholecystectomy without incidents. MATERIAL AND METHODS: The cohort was composed of 32 patients aged 47 ± 18 years (78% women) who underwent BDR due to BDIC. For purposes of comparison, a cohort of patients who underwent a cholecystectomy without incident was chosen. These cohorts were paired 1:1 by age (± 1 year), gender and type of surgery. The SF-36 quality of life survey was applied in person or by telephone. The score was calculated as proposed by the RAND group. RESULTS: The cohort of BDR patients was comprised of 32 patients, with an average age of 47 ± 17.6 years, with a predominance of women (78%). The mean number of hospitalization days among BDR patients was 20 ± 11.8. The average follow-up was 7 ± 5 years. The mean score of patients undergoing RVB or cholecystectomy without complications was evaluated, without finding differences in the score of the different domains of the SF-36 scale. Conclusions: In the present study no significant differences were found in QL between the patients with BDIC who underwent BDR and patients who underwent a cholecystectomy without complications.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Quality of Life , Cholecystectomy/adverse effects , Bile Ducts/surgery , Bile Ducts/injuries , Surveys and Questionnaires
16.
Rev. colomb. cir ; 37(3): 480-491, junio 14, 2022.
Article in Spanish | LILACS | ID: biblio-1378833

ABSTRACT

Introducción. La colelitiasis tiene una prevalencia del 15 % y el 21 % tendrá coledocolitiasis al momento de la colecistectomía, con 50 % de probabilidad de presentar complicaciones asociadas. Desde el advenimiento de la colecistectomía laparoscópica, el abordaje de la coledocolitiasis ha sido endoscópico, usualmente en un tiempo diferente al vesicular, sin embargo, los avances en laparoscopia han permitido explorar la vía biliar común por la misma vía, pudiendo realizar ambos procedimientos en el mismo tiempo de forma segura. Métodos. Se realizó una búsqueda de la literatura existente con relación al enfoque para el manejo de la colecisto-coledocolitasis en un paso comparado con dos pasos. Resultados. Existe evidencia que demuestra mayor efectividad del abordaje en dos pasos, con CPRE y posterior colecistectomía laparoscópica, sobre el abordaje en un paso, especialmente en la tasa de fuga biliar y de cálculos retenidos. El enfoque en un paso con exploración de vías biliares y colecistectomía laparoscópica en el mismo tiempo es seguro, con alta tasa de éxito, baja incidencia de complicaciones, menor estancia hospitalaria y costos. Conclusión. El abordaje laparoscópico en un solo paso es un procedimiento seguro y eficaz para el manejo de la colecisto-coledocolitiasis, con el beneficio de estancia hospitalaria menor, sin embargo, se requieren habilidades técnicas avanzadas en cirugía laparoscópica. En nuestro medio ya existe una infraestructura para el manejo híbrido con CPRE y colecistectomía laparoscópica, pudiéndose realizar ambos en el mismo tiempo, para reducir estancia y costos.


Introduction. Cholelithiasis has a prevalence of 15%, and 21% will have choledocholithiasis at the time of cholecystectomy, with a 50% probability of presenting associated complications. Since the advent of laparoscopic cholecystectomy, the approach to choledocholithiasis has been endoscopic, normative at a different time than the gallbladder; however, advances in laparoscopy have made it possible to explore the common bile duct by the same route, being able to perform both procedures in a single time safely. Methods. A search of the existing literature was performed regarding the one-step approach compared to the two-step approach for the management of cholelithiasis and choledocholithiasis. Results. There is evidence that demonstrates greater effectiveness of the two-step approach with ERCP and subsequent laparoscopic cholecystectomy over the one-step approach, especially in the rate of bile leak and the incidence of retained stones. The one-step approach with bile duct exploration and laparoscopic cholecystectomy at the same time is safe, with a high success rate, low incidence of complications, shorter hospital stay, and lower costs. Conclusion. The one-step laparoscopic approach is a safe and effective procedure for the management cholelithiasis and concomitant choledocholithiasis, with the benefit of a shorter hospital stay; however, advanced technical skills in laparoscopic surgery are required. In our environment there is already an infrastructure for hybrid management with ERCP and laparoscopic cholecystectomy, both of which can be performed at the same time to reduce hospital stay and costs.


Subject(s)
Humans , Bile Ducts , Cholelithiasis , Choledocholithiasis , Cholecystectomy , Cholangiopancreatography, Endoscopic Retrograde , Laparoscopy
17.
Rev. argent. cir ; 114(1): 44-50, mar. 2022. graf
Article in English, Spanish | LILACS, BINACIS | ID: biblio-1376375

ABSTRACT

RESUMEN Las dilataciones quísticas congénitas de la vía biliar extrahepática son infrecuentes, principalmente en Occidente, y afectan sobre todo a niños pero son poco comunes en adultos. El diagnóstico requiere un alto índice de sospecha y suele llevarse a cabo con estudios colangiográficos de los cuales la CRMN es, en la actualidad, el de mayor utilidad. Es conocido el aumento de malignización de estas dilataciones, por lo que el tratamiento completo de la bolsa quística es obligatorio.


ABSTRACT Congenital dilatation of extrahepatic bile ducts is rare in the Western countries and is more common in children than in adults. The diagnosis requires high level of suspicion and is made by cholangiography tests, among which MRCP is the most useful nowadays. Malignant transformation of these cystic dilatations is well-known; therefore, complete resection of the cystic pouch is mandatory.


Subject(s)
Cholecystitis/surgery , Bile Ducts, Extrahepatic/surgery , Bile Ducts , Cholecystectomy , Retrospective Studies , Cysts/surgery , Dilatation
18.
Rev. cir. (Impr.) ; 74(1): 98-102, feb. 2022. ilus
Article in Spanish | LILACS | ID: biblio-1388925

ABSTRACT

Resumen Introducción: El vólvulo de vesícula biliar (VVB) es una causa extremadamente rara de colecistitis aguda. Aproximadamente 500 casos han sido reportados en la literatura mundial. Puede generar una obstrucción total del drenaje vesicular e isquemia con alto riesgo de progresar a perforación y peritonitis biliar. Caso clínico: Mujer de 90 años consultó por dolor hipogástrico de inicio súbito, asociado a masa abdominal palpable y dolorosa en flanco y fosa ilíaca derecha. Tomografía axial computada de abdomen y pelvis demostró una acentuada distensión de la vesícula biliar, ubicada por fuera de la fosa vesicular y con un punto sugerente de torsión. Fue sometida a laparotomía exploradora, desvolvulación seguida de colecistectomía, con evolución posoperatoria favorable. Discusión: Para el desarrollo de un VVB se requiere una "vesícula flotante", su cuadro clínico es inespecífico y muchas veces es confundido con una colecistitis aguda litiásica, su diagnóstico preoperatorio es difícil pese al estudio con imágenes. La intervención quirúrgica oportuna es el único tratamiento resolutivo, con excelentes resultados. Conclusión: La VVB es una patología rara, representa un desafío diagnóstico tanto para cirujanos como radiólogos.


Introduction: Gallbladder volvulus (GV) is an extremely rare cause of acute cholecystitis. Approximately 500 cases have been reported in world literature. It can lead to total obstruction of the gallbladder drainage and ischemia with a high risk of progressing to perforation and biliary peritonitis. Case report: 90-year-old woman consulted due to hypogastric pain of sudden onset, associated with painful palpable abdominal mass in the flank and right iliac fossa. Computed axial tomography of the abdomen and pelvis demonstrated an accentuated distention of the gallbladder, located outside the gallbladder fossa and with a point suggestive of torsion. She underwent exploratory laparotomy, devulvulation followed by cholecystectomy, with favorable postoperative evolution. Discussion: The development of GV requires a "floating gallbladder", its clinical picture is non-specific and is often confused with acute lithiasic cholecystitis. Its preoperative diagnosis is difficult despite the imaging study. Timely surgical intervention is the only resolutive treatment, with excellent results. Conclusion: GV is a rare pathology, it represents a diagnostic challenge for both surgeons and radiologists.


Subject(s)
Humans , Female , Aged, 80 and over , Gallbladder/pathology , Gallbladder Diseases/diagnosis , Cholecystectomy , Tomography, X-Ray Computed
19.
Rev. venez. cir ; 75(1): 24-28, ene. 2022. graf
Article in Spanish | LILACS, LIVECS | ID: biblio-1391599

ABSTRACT

El objetivo de la investigación es analizar la incidencia de los factores de riesgo para el desarrollo de colelitiasis en pacientes menores de 40 años colecistectomizados en el Hospital Ricardo Baquero González. Periodo enero 2019 ­ diciembre 2021.Método: Se realizó un estudio retrospectivo; se analizaron los datos de los de los pacientes diagnosticados e intervenidos por litiasis vesicular. Resultados: Arrojaron que la muestra fue de 151 pacientes; 70% es de sexo femenino y el 30% masculino. El 41% de los pacientes tiene menos de 40 años. En los factores de riesgo se destaca que el 42% son del tipo familiar, el 40% de las mujeres utiliza anticonceptivos orales y el 40% de los pacientes presenta sobrepeso. Conclusión: Se concluye que los casos de litiasis vesicular se encuentran asociados de forma mayoritaria al sexo femenino y a factores de riesgos familiares y al sobrepeso; en cuanto a las mujeres, hubo alta incidencia de casos de litiasis vesicular en aquellas que emplean anticonceptivos orales. Además, en la investigación se observó un aumento en los casos de litiasis vesicular en pacientes que no se encuentran dentro de los grupos de riesgo, como son mujeres menores de 40 años, con peso normal y con pocas gestas(AU)


he objective of the research is to analyze the incidence of risk factors for the development of cholelithiasis in patients under 40 years of age who underwent cholecystectomy at the Ricardo Baquero González Hospital. Period January 2019 - December 2021.Methodi: retrospective study was carried out; Data from patients diagnosed and operated on for gallstones were analyzed. Results: showed that the sample was 151 patients; 70% are female and 30% male. 41% of patients have an age under 40 years old. In the risk factors, it is highlighted that 42% are of the family type, 40% of the women in the sample use oral contraceptives and 40% of the patients are overweight. Concluded: From the investigation it is concluded that the cases of vesicular lithiasis are mostly associated with the female sex and family risk factors and overweight; As for women, there was a high incidence of cases of gallstones in those who use oral contraceptives. In addition, the investigation observed an increase in cases of gallstones in patients who are not within the risk(AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Cholecystectomy , Gallstones/complications , Risk Factors , Cholelithiasis/complications , Lithiasis/complications
20.
San Salvador; s.n; 2022. 78 p.
Thesis in Spanish | BISSAL, LILACS | ID: biblio-1413891

ABSTRACT

Introducción. Las patologías de la vesícula biliar mayormente encontradas son la colelitiasis y colecistitis, las cuales se presentan con más frecuencia en el sexo femenino y son la sexta causa nacional de egreso hospitalario. El tratamiento quirúrgico es el más indicado. Representando un problema de salud y económico relevante para el país. Objetivo. Determinar los factores asociados al retraso en la nutrición enteral en pacientes posterior a colecistectomía en el Hospital Militar Central. Metodología. Estudio observacional y retrospectivo. Con una muestra de 193 expedientes clínicos de pacientes a quienes se les realizó la colecistectomía en el Hospital Militar Central de enero del año 2021 a junio del año 2022, (18 meses). Resultados. Se puede comprobar que no hay significancia estadística de asociación entre las variables de sexo, edad, comorbilidades del paciente y derrame del contenido biliar con respecto al inicio de la nutrición enteral. No así con la duración de cirugía, apremio quirúrgico, tipo de abordaje, estado de la vesícula biliar, presencia de dreno, que si se ve relacionado con respecto al inicio de la nutrición enteral. Pacientes con una vía oral temprana poseen un egreso hospitalario más rápido, con respecto a la nutrición enteral tardía. Conclusión. Los factores asociados al retraso de la alimentación enteral temprana se clasifican en tres grupos: variables prequirúrgicas, transquirurgicas y postquirúrgicas. El iniciar con una dieta enteral temprana reduce la cantidad de complicaciones que pudiesen presentarse. La estancia hospitalaria en pacientes con un inicio de la vía oral temprana se ve reducida con respecto pacientes con dieta enteral tardía.


Introduction. The most commonly found pathologies of the gallbladder are cholelithiasis and cholecystitis, which occur more frequently in females and are the sixth national cause of hospital discharge. Surgical treatment is the most indicated. Representing a relevant health and economic problem for the country. Aim. To determine the factors associated with the delay in enteral nutrition in patients after cholecystectomy at the Central Military Hospital. Methodology. Observational and retrospective study. With a sample of 193 clinical records of patients who underwent cholecystectomy at the Central Military Hospital from January 2021 to June 2022, (18 months). Results. It can be verified that there is no statistical significance of association between the variables of sex, age, patient comorbidities and spillage of bile content with respect to the start of enteral nutrition. Not so with the duration of surgery, surgical urgency, type of approach, state of the gallbladder, presence of drainage, which is related to the start of enteral nutrition. Patients with an early oral route have a faster hospital discharge, with respect to late enteral nutrition. Conclution. The factors associated with the delay of early enteral feeding are classified into three groups: pre-surgical, trans-surgical and post-surgical variables. Starting an enteral diet early reduces the number of complications that could occur. The hospital stay in patients with an early initiation of the oral route is reduced compared to patients with a late enteral diet.


Subject(s)
Cholecystectomy , Postoperative Complications , Gallbladder
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