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1.
Fisioter. Bras ; 22(5): 712-723, Nov 11, 2021.
Article in Portuguese | LILACS | ID: biblio-1353487

ABSTRACT

A lipodistrofia localizada é o aumento na densidade e espessura do tecido adiposo da hipoderme. O gel crioterápico ativa o metabolismo causando resfriamento da pele, estimulando a termogênese para que aconteça a lipólise. Objetivo: Comparar o resultado do gel crioterápico na gordura localizada abdominal antes e após o tratamento. Métodos: O estudo foi composto por 30 mulheres entre 20 e 40 anos, sedentárias e com lipodistrofia abdominal, submetidas a 10 sessões de tratamento. Foi comparado o IMC, perimetria, adipometria, e bioimpedância, análise do perfil sociodemográfico e o grau de satisfação, por meio de frequências e percentuais, antes e após o tratamento. Resultados: Houve diferença significativa na satisfação corporal das pacientes entre o início e o final do tratamento (p < 0,05). Para as variáveis de bioimpedância, adipometria, IMC e perimetria não houve significância estatística (p > 0,05). Todavia, foi observado resultado positivo através de fotos comparativas ao final do tratamento. Conclusão: Foi identificada, através do perfil sociodemográfico, a prevalência da faixa etária de 20 a 30 anos, de cor parda, estudantes e residentes da cidade de Vitória e Serra. Para o IMC, perimetria, adipometria e bioimpedância não houve resultados satisfatórios. Contudo, para o questionário de satisfação, constatou-se melhora da satisfação corporal das participantes. (AU)


Subject(s)
Female , Adult , Lipodystrophy , Lipolysis , Women's Health , Cryotherapy
3.
Rev. venez. cir. ortop. traumatol ; 53(1): 20-26, jun. 2021. ilus
Article in Spanish | LILACS, LIVECS | ID: biblio-1252895

ABSTRACT

Cuando fracasa el tratamiento conservador en el Estadio I de Disfunción del Tendón Tibial posterior (DTTP), se debe indicar sinovectomía y debridamiento del tendón. En este estudio evaluamos la evolución con 8 años mínimo de seguimiento, de los pacientes con esta patología tratados vía tenoscópica. Este es un estudio retrospectivo de pacientes operados entre el año 2008 y el año 2011. En ese período de tiempo se intervinieron 11 pacientes con esta patología. Sólo 9 de los 11 pacientes operados pudieron ser evaluados. 7 pacientes mejoraron su sintomatología según el VAS y no progresaron a estadio II. En 3 pacientes se evidenció lesión tendinosa durante la tendoscopía y ameritaron reparación a cielo abierto. La sinovectomía tendoscópica del TTP es un procedimiento quirúrgico efectivo para tratar a los pacientes con DTTP Estadio I, rebeldes a tratamiento conservador(AU)


When conservative treatment fails for Stage I Posterior Tibial tendon dysfunction (PTTD), synovectomy and tendon debridement is indicated. In this study we evaluate tendoscopic treatment results for this pathology with a minimum of 8 years follow up. This is a retrospective study of patients after tendoscopic surgery performed between 2008 and 2011. 9 of the 11 patients were available for evaluation. 7 improved their symptoms according to VAS scale, and did not progress to stage II. In 3 patients tendon tear was visualized during tendoscopy and needed open repair. PTT tendoscopy is an effective surgical treatment to treat Stage I PTTD, failing to conservative treatment(AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Flatfoot , Magnetic Resonance Spectroscopy , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Posterior Tibial Tendon Dysfunction/pathology , Tendinopathy , Synovectomy , Ultrasonics , Cryotherapy , Diagnostic Techniques and Procedures , Debridement
4.
Rev. cuba. med. gen. integr ; 37(2): e1340, 2021. graf
Article in Spanish | LILACS, CUMED | ID: biblio-1352017

ABSTRACT

Introducción: El cáncer de piel es el tipo de cáncer más frecuente en el ser humano, el carcinoma basocelular es el más común de todos los cánceres de piel (80-90 por ciento). Excepcionalmente producen metástasis, pero pueden causar significativa morbilidad e involucran a edades más jóvenes, se tratan con éxito mediante cirugía, radioterapia, quimioterapia y crioterapia, generalmente en el nivel secundario de salud, sin embargo, estos tratamientos no siempre son posibles o deseables. El HeberFERON® es una combinación de interferones alfa y gamma humanos recombinantes, que ha mostrado producir efectos sinérgicos en la reducción de la proliferación de varias líneas de células cancerosas, esta formulación ha sido aprobada en Cuba para el tratamiento del carcinoma basocelular. Presentación de casos: Se presentaron tres casos con diagnóstico de carcinoma basocelular, localizados en la cara, tratados con HeberFERON®, en dos casos fue observada la desaparición de la lesión al finalizar la tercera semana de tratamiento. En el tercer caso, una mujer de 84 años de edad, al finalizar el primer ciclo de tratamiento, fue reducido el tamaño de la lesión tratada y desapareció otra lesión adyacente que no recibió directamente tratamiento, la lesión residual, en esta paciente, fue valorada por ultrasonido para determinar su extensión y profundidad, en los tres casos las reacciones adversas fueron leves y transitorias. Conclusiones: El HeberFERON® es una opción efectiva y segura para el tratamiento del carcinoma basocelular en la atención primaria de salud en Cuba(AU)


Introduction: Skin cancer is the commonest type of cancer in humans. Basal cell carcinoma is the commonest of all skin cancers, accounting for 80 percent to 90 percent of all cases. Exceptionally, they metastasize, but can cause significant morbidity and involve younger ages. They are successfully treated by surgery, radiotherapy, chemotherapy and cryotherapy, mostly at the secondary level of health. However, these treatments are not always possible or desirable. HeberFERON® is a combination of recombinant human alpha and gamma interferons, which has been shown to produce synergistic effects in reducing the proliferation of several lines of cancer cells. This formulation has been approved in Cuba for treating basal cell carcinoma. Case presentation: Three cases are presented with a diagnosis of basal cell carcinoma, located on the face, treated with HeberFERON®. In two cases, the lesion was observed to disappear at the end of the third week of treatment. In the third case, an 84-year-old woman, at the end of the first cycle of treatment, the size of the treated lesion was reduced and another adjacent lesion disappeared, which did not receive direct treatment. In this patient, the residual lesion was assessed by ultrasound to determine its extension and depth. In the three cases, the adverse reactions were mild and transitory. Conclusions: HeberFERON® is an effective and safe option for treating basal cell carcinoma in primary health care in Cuba(AU)


Subject(s)
Humans , Primary Health Care , Carcinoma, Basal Cell/diagnosis , Carcinoma, Basal Cell/drug therapy , Ultrasonography/methods , Cryotherapy/methods , Reference Drugs , Carcinoma, Basal Cell/surgery , Cuba
5.
Rev. cuba. estomatol ; 58(1): e3028, ene.-mar. 2021. graf
Article in Portuguese | LILACS, CUMED | ID: biblio-1156424

ABSTRACT

Introdução: O cisto dentígero se origina pela separação do folículo que fica ao redor da coroa de um dente incluso. É o tipo mais comum de cisto odontogênico do desenvolvimento. O seu crescimento é lento, assintomático, e pode atingir grandes dimensões. Objetivo: Relatar um caso clínico cirúrgico de cisto dentígero com transformação ameloblástica, localizado na mandíbula, de paciente, gênero feminino, melanoderma, 14 anos. Caso clínico: Ao exame radiográfico apresentou área radiolúcida unilocular com margem bem definida e esclerótica envolvendo a coroa das unidades 48 e 47. Foi realizada enucleação e curetagem da lesão com exodontia destas unidades sob anestesia local em ambulatório, e aplicada a crioterapia na loja óssea. Encaminhou-se o conteúdo da lesão para exame histopatológico e o diagnóstico de cisto dentígero com transformação ameloblástica foi fechado. Comentários principais: No momento a paciente encontra-se em acompanhamento pós-operatório de 3 anos com neoformação óssea e sem recidivas(AU)


Introducción: El quiste dentígero se origina por la separación del folículo que se queda alrededor de la corona de un diente no erupcionado. Es el tipo más común de quiste odontogénico de desarrollo. Su crecimiento es lento, asintomático y puede alcanzar grandes dimensiones. Objetivo: Reportar un caso quirúrgico de quiste dentígero con transformación ameloblástica. Presentación del caso: Paciente femenina de 14 años, de color de piel negra. La radiografía demostró una radiolucidez unilocular con márgenes bien definidos que envolvían la corona de los dientes 48 y 47. El tratamiento involucró una combinación de enucleación y curetaje de la lesión, exodoncia de los dientes y crioterapia para desvitalizar el hueso circundante. Se realizó el examen histopatológico, luego, se confirmó el diagnóstico de quiste dentígero con transformación ameloblástica. Conclusiones: Al momento de la redacción del reporte la paciente se encontraba en seguimiento posoperatorio de tres años con neoformación ósea y sin recidivas(AU)


Introduction: Dentigerous cysts are caused by the separation of the follicle remaining around the crown of unerupted teeth. They are the most common type of developmental odontogenic cyst. Their growth is slow and asymptomatic, and they may reach large dimensions. Objective: Report a surgical case of dentigerous cyst with ameloblastic transformation. Case presentation: A case is presented of a black female 14-year-old patient. Radiography revealed an area of unilocular radiolucency with well-defined margins enveloping the crowns of teeth 48 and 47. Treatment was a combination of enucleation and curettage of the lesion, exodontia of the teeth and cryotherapy to devitalize the surrounding bone. Eventual histopathological examination confirmed the diagnosis of dentigerous cyst with ameloblastic transformation. Conclusions: At the time when the report was written, the patient had been followed up for three years after surgery, showing bone neoformation and no recurrence of the lesion(AU)


Subject(s)
Humans , Female , Adolescent , Ameloblastoma/physiopathology , Dentigerous Cyst/surgery , Cryotherapy/methods , Research Report
6.
Rev. cuba. oftalmol ; 34(1): e942, 2021. graf
Article in Spanish | LILACS, CUMED | ID: biblio-1289538

ABSTRACT

La oftalmomiasis es una enfermedad poco frecuente, causada por artrópodos; en este caso por la mosca adulta. Presentamos el caso de una paciente femenina, de 44 años de edad, con antecedentes de inmunosupresión severa secundaria a VIH, quien fue atendida en el Servicio de Oftalmología por molestia ocular. Presentaba un aumento de volumen circunscrito en conjuntiva que se extendía sobre la córnea nasal del ojo izquierdo, de aspecto blanco nacarado, deslustrado. Se le realizó exéresis de la lesión y crioterapia. Posteriormente se le aplicó colirio de mitomicina C. A los siete meses la paciente regresó a la consulta con un cuadro de complicación franca y severa de la lesión, con destrucción de los tejidos de la órbita y múltiples cavernas ocupadas por cientos de larvas de moscas(AU)


Ophthalmomiasis is a rare disease, caused by arthropods; in this case by the adult fly. We present the case of a 44-year-old female patient, with a history of severe immunosuppression secondary to HIV, who was treated at the Ophthalmology Service for ocular discomfort. She presented a circumscribed increase in volume in the conjunctiva that extended over the nasal cornea of ​​the left eye, with a pearly white, tarnished appearance. Excision of the lesion and cryotherapy were performed. Subsequently, mitomycin C eye drops were applied. Seven months later, the patient returned to the consultation with a frank and severe complication of the lesion, with destruction of the tissues of the orbit and multiple caverns occupied by hundreds of fly larvae(AU)


Subject(s)
Humans , Female , Adult , Mitomycin/therapeutic use , Cryotherapy/methods , Rare Diseases/therapy , Myiasis/epidemiology
7.
Article in Chinese | WPRIM | ID: wpr-877551

ABSTRACT

OBJECTIVE@#To compare the clinical therapeutic effect of fire needling stripping after local anesthesia, simple fire needling and liquid nitrogen cryotherapy on verruca vulgaris.@*METHODS@#A total of 900 patients with verruca vulgaris were randomized into a fire needling stripping group (300 cases, 2 cases dropped off), a fire needling group (300 cases, 4 cases dropped off) and a liquid nitrogen cryotherapy group (300 cases, 5 cases dropped off). After local anesthesia of compound lidocaine cream, fire needling therapy was adopted, and the necrotic tissue of verruca was stripped in the fire needling stripping group. Simple fire needling therapy was adopted in the fire needling group, without local anesthesia and stripping. Liquid nitrogen cryotherapy was adopted in the liquid nitrogen cryotherapy group. The treatment was given once a week, and totally 3 weeks were required in the 3 groups. The skin lesion scores of number, area, thickness, color, pruritus, isomorphism and the level of T lymphocyte (CD@*RESULTS@#Compared before treatment, the skin lesion scores were decreased (@*CONCLUSION@#Fire needling stripping after local anesthesia can effectively treat the verruca vulgaris, improve the skin lesion and immunity, its therapeutic effect is superior to simple fire needling and liquid nitrogen cryotherapy.


Subject(s)
Anesthesia, Local , Cryotherapy , Humans , Treatment Outcome , Vascular Surgical Procedures , Warts/therapy
8.
Adv Rheumatol ; 61: 3, 2021. tab, graf
Article in English | LILACS | ID: biblio-1152737

ABSTRACT

Abstract Introduction: Whole-body cryotherapy (WBC) has shown to be beneficial in the treatment of fibromyalgia (FM). There is cumulative evidence that cytokines play a crucial role in FM. It's unknown whether clinical effects of WBC can be demonstrated at the molecular level and how long the effects last. Methods: We compared effects of serial WBC (6 sessions (- 130 °C in 6 weeks) in FM patients and healthy controls (HC). Primary outcome was the change in pain level (visual analogue scale 0-100 mm) after 6 sessions. Secondary outcomes were a change in disease activity (revised Fibromyalgia Impact Questionnaire) and pain after 3 sessions and 3 months after discontinued therapy and in cytokine levels (interleukin (IL-)1, IL-6, tumor necrosis factor α (TNF-α) and IL-10). The patients' opinions on the satisfaction, effectiveness and significance of WBC were evaluated. Results: Twenty-three FM patients and 30 HC were enrolled. WBC resulted in a significant reduction in pain and disease activity after 3 and 6 sessions. No clinical benefit could be measured 3 months after discontinued treatment. Overall, probands were satisfied with WBC and considered WBC to be important and effective. FM patients had significantly different levels of IL-1, IL-6, TNF-α and IL-10 at each reading point compared to HC. Levels of IL-1, IL-6 and IL-10 were significantly altered over time in FM patients. Compared to HC FM patients showed a significantly different response of IL1, - 6 and - 10 to WBC. Conclusion: Serial WBC is a fast acting and effective treatment for FM. Proven effects of WBC may be explained by changes in cytokines.(AU)


Subject(s)
Humans , Fibromyalgia/therapy , Cytokines , Cryotherapy/instrumentation , Surveys and Questionnaires
9.
Rev. Fac. Med. (Bogotá) ; 68(4): 527-532, oct.-dic. 2020. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1149553

ABSTRACT

Resumen Introducción. La crioterapia se usa para tratar la inflamación articular aguda, sin embargo su efecto sobre el músculo relacionado con la articulación inflamada aún no ha sido estudiado. Objetivo. Evaluar el efecto de la crioterapia sobre la articulación tibiotarsiana en el área de sección transversa (AST) de los músculos tibial anterior (TA) y sóleo en ratas con inflamación articular aguda. Materiales y métodos. Estudio experimental realizado en 32 ratas Wistar que fueron asignadas aleatoriamente a cuatro grupos: Control, Inflamación, Crioterapia-A y Crioterapia-B. El AST de las fibras de los músculos se midió 72 horas después de haberse iniciado el experimento. Resultados. En el músculo TA hubo una reducción significativa del AST de las fibras musculares en los grupos Inflamación y Crioterapia-B en comparación con el grupo Control, mientras que en el grupo Crioterapia-A no se observó una reducción significativa en dicha área al compararlo con el Control. En el caso del músculo sóleo, se observó una reducción significativa del área en todos los grupos experimentales. Conclusión. El uso de crioterapia una vez al día por tres días atenúa el efecto atrófico de la inflamación articular aguda sobre el músculo TA, lo que confirma su importancia en el control del efecto deletéreo de la inflamación aguda sobre músculos de contracción rápida.


Abstract Introduction: Cryotherapy is used to treat acute joint inflammation, but its effect on muscles associated with the injured joint has not yet been studied. Objective: To evaluate the effect of cryotherapy on the tibiotarsal joint in the cross-sectional area (CSA) of tibialis anterior (TA) and soleus muscles in rats with acute joint inflammation. Materials and methods: Experimental study conducted on 32 Wistar rats that were randomly assigned to four groups: Control, Inflammation, Cryotherapy-A and Cryotherapy-B. The CSA of muscle fibers was measured 72 hours after initiating the experiment. Results: In the case of the TA muscle, there was a significant reduction in the CSA muscle fibers in the Inflammation and Cryotherapy-B groups compared to the Control group, while no significant reduction was observed in the Cryotherapy-A group in relation to the Control group. Regarding the soleus muscle, a significant CSA reduction was observed in all experimental groups. Conclusion: The use of cryotherapy once a day for three days attenuates the atrophic effect of acute joint inflammation on the TA muscle, confirming its importance for controlling the deleterious effects of acute inflammation on fast-twitch muscles.


Subject(s)
Humans , Cryotherapy , Rehabilitation , Inflammation
10.
Arq. bras. med. vet. zootec. (Online) ; 72(3): 688-694, May-June, 2020.
Article in English | LILACS, VETINDEX | ID: biblio-1128763

ABSTRACT

While solving the problem of sport horses' pathologies it is important to choose safe and environmentally friendly methods, including cryotherapy, which is the topic of our research. The use of cryotherapy is a promising means of treatment of primary injury, rehabilitation in post-traumatic conditions and in chronic injuries. Prospects of cryotherapy applications in horse breeding, in particular in sports and prize areas, were researched. It was found out that modern sport horses training and their involvement in competitions is associated with serious stress on their locomotor system and maximum mobilization of all body systems, which overstrains certain muscle groups, determines increased probability and severity of injury incidence, reduction of sport longevity and worse performance in competitions.(AU)


Na resolução do problema das patologias dos cavalos esportivos é importante escolher métodos seguros e ecológicos, incluindo a crioterapia, que é o tópico desta pesquisa. O uso da crioterapia é um meio promissor no tratamento de lesões primárias, reabilitação em condições pós-traumáticas e lesões crônicas. Foram pesquisadas as perspectivas de aplicações da crioterapia na criação de cavalos, particularmente em esportes e prêmios. Verificou-se que o treinamento moderno de cavalos esportivos e seu envolvimento em competições está associado com severo estresse sobre seu sistema locomotor e mobilização máxima de todos os sistemas corporais, que sobrecarregam certos grupos musculares, determinam maior probabilidade e severidade da incidência de lesões, e reduzem a longevidade no esporte e pior desempenho em competições.(AU)


Subject(s)
Animals , Osteoarthritis/veterinary , Wounds and Injuries/therapy , Cryotherapy/trends , Horses , Physical Conditioning, Animal/trends , Running
11.
Rev. cuba. oftalmol ; 33(2): e816, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1139082

ABSTRACT

RESUMEN El papiloma conjuntival es un tumor de células escamosas adquirido, benigno, que se puede presentar a cualquier edad, pero más frecuentemente en la tercera y cuarta décadas de la vida. Los papilomas están asociados con la infección del virus papiloma humano, usualmente los tipos 6 y 11. Se presenta un paciente quien se encuentra en la cuarta década de la vida, fumador. Acudió al Servicio de Oculoplastia por aumento del volumen conjuntival en el ojo izquierdo. Luego del interrogatorio y de un examen ocular exhaustivo, se realizó el diagnóstico clínico de papiloma conjuntival recurrente. Se propuso exéresis, crioterapia y biopsia de las lesiones conjuntivales. Posterior a la intervención, se confirmó el diagnóstico anatomopatológico y se reajustó el tratamiento tópico ocular con interferón, con lo cual se obtuvieron resultados satisfactorios(AU)


ABSTRACT Conjunctival papilloma is a benign acquired squamous cell tumor occurring at any age, but more commonly in the third and fourth decades of life. Papillomas are associated to human papillomavirus infection, usually of types 6 and 11. A case is presented of a male smoker patient in his fourth decade of life. The patient attended the Oculoplastics Service due to conjunctival volume increase in his left eye. Interrogation and exhaustive ocular examination led to the clinical diagnosis of recurrent conjunctival papilloma. Exeresis, cryotherapy and biopsy of the conjunctival lesions were indicated. The anatomopathological diagnosis was confirmed after the intervention and a readjustment was made of the topical ocular treatment with interferon, with which satisfactory results were obtained(AU)


Subject(s)
Humans , Male , Adult , Papilloma/diagnosis , Interferons/therapeutic use , Cryotherapy/methods , Papillomavirus Infections/etiology
12.
Rev. odontol. UNESP (Online) ; 49: e20200026, 2020. tab, graf
Article in Portuguese | LILACS, BBO | ID: biblio-1289853

ABSTRACT

Resumo Introdução O trismo é uma restrição na abertura bucal de até 3,5 cm e é um dos efeitos colaterais mais comuns da radioterapia na região da cabeça e pescoço. Tal condição afeta funções cotidianas simples, como: mastigar, deglutir, falar e até exercer higiene bucal, acarretando danos não só físicos como emocionais aos indivíduos acometidos. Evidencia-se assim a necessidade da busca de tratamentos que revertam ou atenuem tal quadro. Objetivo O objetivo do estudo é investigar o comportamento dos músculos masseter e supra-hioideos durante a deglutição antes e após o crioalongamento associado à massoterapia, em pacientes pós-neoplasia bucal com trismo devido à radioterapia. Material e método A amostra final foi constituída por oito sujeitos, com faixa etária entre 40 e 64 anos, gêneros masculino e feminino, com abertura bucal menor ou igual a 3,5 cm. Para a realização da pesquisa, foram realizadas duas avaliações eletromiográficas, uma no início e outra no final do tratamento. Com 15 atendimentos, uma vez por semana, com manobras de crioalongamento associado à massoterapia nos músculos masseter e grupo muscular dos supra-hioideos. Resultado Após a intervenção com crioalongamento e massoterapia, foi observada diferença significativa apenas no comportamento do grupo muscular dos supra-hioideos, fato não constatado no músculo masseter. Conclusão Foi encontrada diferença significativa no comportamento do grupo muscular supra-hioideo e melhora na abertura de boca dos sujeitos. Contudo, os resultados deste estudo devem ser confirmados em casuísticas maiores.


Abstract Introduction Trismus is a restriction in the buccal opening up to 3.5cm and is one of the most frequent side effect of head and neck regions radiotherapy. This condition affects simple daily activities such as chewing, swallowing speaking and even buccal hygiene, leading to not only physical but emotional damages to the subjects. This puts in evidence the need to find treatments to revert or soften this condition. Objective This study investigates the behavior of masseter and suprahyoid muscles during swallowing before and after the cryotherapy associated to the massage in patients post buccal neoplasm with trismus due to radiotherapy. Material and method The final sample was composed of 8 subjects, aged between 40 an 64 years, both female and male with buccal opening equal to or smaller than 3.5cm. Two electromyographic evaluations were conducted to perform this research, one in the beginning and one in the end of the treatment. The study was composed of 15 treatment sessions, once a week, consisting of cryotherapy maneuvers and massage in masseters and supra-hyoids muscle groups. Result There was a significant difference in the behavior of the supra-hyoid muscles group, this fact was not observed in the masseter muscles group. Conclusion The study concluded that after the intervention with cryotherapy and massage sessions, was observed a significant difference in the behavior of the upperhyoid muscles group and an improvement of the subjects' mouth opening capacity. However, the results of this study must be confirmed in a larger sample size.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Trismus , Mouth Neoplasms , Cryotherapy , Massage , Health Impact Assessment
13.
Rev. saúde pública (Online) ; 54: 27, 2020. tab, graf
Article in English | LILACS | ID: biblio-1094408

ABSTRACT

ABSTRACT OBJECTIVES To determine the efficacy and safety of the use of cryotherapy, cold knife or thermocoagulation compared to Loop Electrosurgical Excision Procedure (LEEP) for the treatment of cervical intraepithelial neoplasia. METHODS Systematic review with meta-analysis of randomized controlled trials in women with cervical intraepithelial neoplasia undergoing treatment with cryotherapy, cold knife, or thermo-coagulation compared with LEEP, to estimate its efficacy and safety. The search was conducted on MEDLINE/PUBMED, Cochrane Central Register of Controlled Trials (CENTRAL) and Scopus, until September 2018. RESULTS The total of 72 studies were identified, of which only 8 studies met the inclusion criteria. The treatment of CIN with cold knife decreases the risk of residual disease compared with LEEP (RR, 0.54, 95%CI, 0.30-0.96, p = 0.04). The management of premalignant lesions with cryotherapy, compared with LEEP, increases the risk of disease recurrence by 86% (RR, 1.86, 95%CI, 1.16-2.97, p = 0.01), increases the risk of infections (RR, 1.17, 95%CI, 1.08-1.28, p < 0.001) and reduces the risk of minor bleeding by 51% (RR, 0.49, 95%CI) %, 0.40-0.59, p ≤ 0.001). CONCLUSIONS The treatment of premalignant lesions of cervical cancer with cold knife reduces the risk of residual disease. Nevertheless, cryotherapy reduces the risk of minor bleeding in the 24 hours after treatment and increases the risk of recurrence of disease and infections.


RESUMEN OBJETIVOS Evaluar la eficacia y seguridad del uso de crioterapia, cono frio o termo-coagulación en comparación con el procedimiento de escisión electroquirúrgica en asa (LEEP) para el manejo de neoplasias intraepiteliales cervicales. MÉTODOS Revisión sistemática de ensayos controlados aleatorizados en mujeres con neoplasia intraepitelial cervical en tratamiento con crioterapia, cono frio, o termo coagulación y LEEP, para estimar su eficacia y seguridad. La búsqueda se realizó en MEDLINE/PUBMED, Registro Cochrane Central de Ensayos Controlados (CENTRAL) y Scopus, hasta setiembre de 2018. RESULTADOS Se identificaron 72 estudios, ocho cumplieron los criterios de inclusión. Cono frio disminuyó el riesgo de enfermedad residual en comparación con LEEP (RR 0,54; IC del 95%, 0,30-0,96, p = 0,04). Crioterapia en comparación con LEEP incrementó el riesgo de recurrencia de enfermedad en un 86,0% (RR 1,86; IC del 95%, 1,16-2,97, p = 0,01) con un tiempo de seguimiento de seis a 24 meses, y de infecciones (RR, 1,17; IC del 95%, 1,08-1,28, p < 0,001); pero redujo el riesgo de sangrado menor en un 51,0% (RR 0,49; IC del 95%, 0,40-0,59, p ≤ 0,001). CONCLUSIONES Cono frio reduce el riesgo de enfermedad residual. Sin embargo, la crioterapia reduce el riesgo de sangrado menor en las 24 horas posteriores al tratamiento e incrementa el riesgo de recurrencia de enfermedad y de infecciones.


Subject(s)
Humans , Female , Uterine Cervical Neoplasms/surgery , Cryotherapy/methods , Cervical Intraepithelial Neoplasia/surgery , Conization/methods , Electrocoagulation/methods , Postoperative Complications , Uterine Cervical Neoplasms/pathology , Risk , Risk Factors , Cervical Intraepithelial Neoplasia/pathology , Neoplasm Recurrence, Local/surgery , Neoplasm Recurrence, Local/pathology
14.
Fisioter. Mov. (Online) ; 33: e003365, 2020. tab, graf
Article in English | LILACS | ID: biblio-1133919

ABSTRACT

Abstract Introduction: Cryotherapy is a technique that involves the application of low temperatures in the treatment of acute injuries, with ice being the simplest and oldest therapeutic modality for this. Objective: To compare two different cold water immersion protocols (standard and intermittent) on the ankle region of healthy volunteers, we analyzed changes in static postural stability, threshold, and pain tolerance immediately after application. Method: This is a quasi-experimental study, controlled clinical trial, and non-probabilistic sampling. The total sample consisted of 40 male patients aged 18 to 30 years. Two different cold water immersion protocols (standard and intermittent) were compared for their effects on pain threshold, tolerance, and static postural stability. Results: There were no significant differences between the groups with regards to the stabilometric variables after the application of both protocols (p > 0.05). There was a significant difference in the threshold and tolerance of the two groups after the application of cold water immersion (p < 0.05); however, there were no significant differences between the groups (p > 0.05). Conclusion: Both cold water immersion protocols proved to be safe for static postural balance, without showing deficits in stabilometric variables. Regarding the analgesic effect, both were effective and significantly increased the threshold and tolerance of ankle pain after cryoimmersion, without any differences between groups. Thus, intermittent 10-minute cold water immersion is sufficient to generate the same analgesic effect as the standard 20-minute pattern, with no change in static postural stability.


Resumo Introdução: A crioterapia é uma técnica que consiste na aplicação de temperaturas mais baixas, sendo o gelo, a modalidade terapêutica mais simples e antiga no tratamento de lesões agudas. Objetivo: Comparar dois protocolos diferentes de crioimersão (padrão e intermitente) sobre a região do tornozelo de voluntários saudáveis, analisando as alterações na estabilidade postural estática e no limiar e tolerância à dor, imediatamente após a aplicação. Método: Trata-se de um estudo de natureza quasi-experimental, do tipo ensaio clínico controlado, com amostragem não probabilística. A amostra total foi constituída de 40 indivíduos do sexo masculino com idade entre 18 e 30 anos, comparando dois protocolos diferentes de crioimersão (padrão e intermitente) e seus efeitos sobre o limiar e tolerância à dor, e estabilidade postural estática. Resultados: Não houve diferenças significativas em relação as variáveis estabilométricas após a aplicação de ambos os protocolos (p>0,05). Houve diferença significativa no limiar e tolerância dos dois grupos após a aplicação da crioimersão (p<0,05), entretanto sem diferenças significativas entre os grupos (p>0,05). Conclusão: Os dois protocolos de crioimersão se mostraram seguros com relação ao equilíbrio postural estático, sem apresentar déficits nas variáveis estabilométricas. Com relação ao efeito analgésico, ambos foram eficazes, aumentando significativamente o limiar e a tolerância de dor no tornozelo após a crioimersão, sem que houvesse diferenças entre os grupos. Dessa forma, percebe-se que a crioimersão intermitente de 10 minutos é suficiente para gerar o mesmo efeito analgésico que a padrão de 20 minutos, sem alteração na estabilidade postural estática.


Subject(s)
Humans , Male , Adolescent , Adult , Ankle Injuries , Cryotherapy , Postural Balance , Musculoskeletal Pain , Non-Randomized Controlled Trials as Topic
15.
Rev. latinoam. enferm. (Online) ; 28: e3363, 2020. tab, graf
Article in English | LILACS, BDENF | ID: biblio-1139216

ABSTRACT

Objective: to evaluate the effect of oral cryotherapy compared to physiological serum on the development of oral mucositis in outpatient cancer patients using the 5-fluorouracil antineoplastic agent. Method: this is a controlled, randomized, double-blind, and multi-center clinical trial, conducted with 60 patients undergoing chemotherapy. The experimental group (n=30) used oral cryotherapy during the infusion of the 5-FU antineoplastic agent, while the control group (n=30) performed mouthwash with physiological serum at their homes. The oral cavity of the participants was assessed at three times: before randomization, and on the 7th and 14th days after using 5-FU. For data analysis, descriptive analyses and the ANOVA, paired t, and McNemar tests were used. Results: there was no statistically significant difference between the experimental and control groups in the assessments regarding the grade of mucositis. However, cryotherapy presented the chance to reduce the presence of intragroup mucositis, between the first and second assessments (p=0.000126). Conclusion: cryotherapy did not obtain statistical significance in relation to oral hygiene with serum, but it proved to be effective intragroup. Record number: RBR-4k7zh3


Objetivo: avaliar o efeito da crioterapia oral em comparação ao soro fisiológico no desenvolvimento de mucosite oral em pacientes oncológicos ambulatoriais em uso de antineoplásico 5-fluorouracil. Método: trata-se de um ensaio clínico controlado, randomizado, duplo-cego, multicêntrico, realizado com 60 pacientes em tratamento quimioterápico. O grupo experimental (n=30) fez uso de crioterapia oral durante a infusão do antineoplásico 5-FU, ao passo que o grupo controle (n=30) realizou bochechos com soro fisiológico em domicílio. A cavidade oral dos participantes foi avaliada em três momentos: antes da randomização, no 7° dia e no 14° dia após o uso do 5-FU. Para a análise dos dados, utilizaram-se análises descritivas e os testes ANOVA, t pareado e McNemar. Resultados: não houve diferença estatística significante entre os grupos experimental e controle nas avaliações quanto ao grau de mucosite. No entanto, a crioterapia teve a chance de reduzir a presença de mucosite intragrupo, entre a primeira e segunda avaliação (p=0,000126). Conclusão: a crioterapia não obteve significância estatística em relação à higiene oral com soro, porém se mostrou efetiva intragrupo. Número de registro: RBR-4k7zh3


Objetivo: evaluar el efecto de la crioterapia oral, comparándola con el suero fisiológico, sobre el desarrollo de mucositis oral en pacientes ambulatorios con cáncer en tratamiento con el antineoplásico 5-fluorouracilo. Método: se trata de un ensayo clínico controlado, aleatorizado, a doble ciego y multicéntrico, realizado con 60 pacientes en tratamiento de quimioterapia. El grupo experimental (n=30) utilizó crioterapia oral durante la administración del agente antineoplásico 5-FU, mientras que el grupo control (n=30) realizó enjuagues con suero fisiológico en su domicilio. La cavidad oral de los participantes se evaluó en tres momentos: antes de la aleatorización, y al 7º y 14º día después de la administración de 5-FU. Para el análisis de los datos, se utilizaron análisis descriptivos y las pruebas ANOVA, t pareada y McNemar. Resultados: en lo que respecta al grado de mucositis, no se registraron diferencias estadísticamente significativas entre el grupo experimental y el de control en las evaluaciones. Sin embargo, la crioterapia exhibió la posibilidad de reducir la presencia de mucositis intragrupo entre la primera y la segunda evaluación (p=0,000126). Conclusión: la crioterapia no alcanzó significancia estadística en comparación con la higiene oral con suero. Sin embargo, demostró ser efectiva intragrupo. Número de registro: RBR-4k7zh3


Subject(s)
Humans , Oral Hygiene , Stomatitis , Pharmaceutical Preparations , Hygiene , Control Groups , Cryotherapy , Drug Therapy , Disease Prevention , Mucositis , Fluorouracil , Antineoplastic Agents
17.
Rev. Ciênc. Méd. Biol. (Impr.) ; 18(3): 421-424, dez 20, 2019. fig
Article in Portuguese | LILACS | ID: biblio-1359280

ABSTRACT

Introdução: o hemangioma é um tumor benigno vascular de origem endotelial, definido por crescimento anormal dos vasos sanguíneos. Essa lesão pode atingir qualquer parte do corpo, porém a região de cabeça e pescoço tem uma incidência de 60% dos casos; na cavidade oral, ela pode se apresentar na língua, na mucosa bucal, no palato, nos lábios. O tratamento é multimodal, incluindo laser, crioterapia, excisão cirúrgica, agentes quimioterápicos e escleroterapia. Objetivo: apresentar um relato de caso de escleroterapia em hemangioma de dorso de língua, tratado com dose única de oleato de monoetanolamina. Metodologia: paciente do sexo feminino, 35 anos, branca, apresentou-se a um consultório particular queixando-se de lesão pigmentada na língua, assintomática, notada após contato com aparelho ortodôntico lingual. Ao exame clínico intrabucal foi observada lesão nódulo papular, de coloração vermelha, localização em dorso de língua, com 0.5 cm de diâmetro e inserção séssil com diagnóstico de hemangioma oral. Tratado em dose única com oleato de monoetanolamina a 0.4ml na proporção de 50%, diluído na solução anestésica local de lidocaína com adrenalina 1\100.000 no centro da lesão. Resultados: a lesão apresentou regressão total da lesão e sem recidiva após uma sessão do tratamento. Conclusão: escleroterapia é um tratamento conservador, eficiente e com resultado estético positivo, nos casos de hemangioma, porém vale ressaltar que esta deve ser devidamente indicada, analisando sempre as suas limitações e os seus benefícios.


Introduction: hemangioma is a benign vascular tumor of endothelial origin defined by abnormal growth of blood vessels. This injury can affect any part of the body, but the head and neck region has an incidence of 60% of cases. In the oral cavity it may be present in the tongue, buccal mucosa, palate, lips. Treatment is multimodal including laser, cryotherapy, surgical excision, chemotherapeutic agents and sclerotherapy. Objective: to present a case report of sclerotherapy in tongue dorsal hemangioma treated with a single dose of monoethanolamine oleate. Methodology: a 35-year-old white female patient presented to a private practice complaining of asymptomatic pigmented tongue injury noted after contact with the lingual orthodontic appliance. Clinical examination revealed a red papular nodule lesion, located on the back of the tongue, 0.5 cm in diameter and sessile insertion diagnosed with Oral Hemangioma. The nodule was treated in the lesion center with a single dose of 0.4 ml monoethanolamine oleate, at a proportion of 50% dilution in 1\100,000 local anesthetic solution of lidocaine with adrenaline. Results: total regression of the lesion and no recurrence was presented after 01 treatment session. Conclusion: sclerotherapy is a conservative treatment, efficient and with positive aesthetic result in cases of Hemangioma, but it is worth mentioning that it should be properly indicated always considering its limitations and its benefits.


Subject(s)
Humans , Female , Adult , Tongue , Sclerotherapy , Hemangioma , Mouth , Cryotherapy , Lasers
18.
Fisioter. Pesqui. (Online) ; 26(2): 185-189, abr.-jun. 2019. tab
Article in Portuguese | LILACS | ID: biblio-1012133

ABSTRACT

RESUMO A espasticidade causada pelo acidente vascular encefálico (AVE) é uma das principais causas de incapacidade funcional no membro superior. O objetivo do estudo foi verificar o efeito da crioterapia associada à cinesioterapia e da estimulação elétrica na capacidade de preensão palmar do membro espástico de pacientes com AVE na fase crônica. Participaram do estudo 40 pacientes com idade média de 60,5 (±9,45) anos e hemiparesia espástica, divididos aleatoriamente em grupo A (GA): submetidos à crioterapia nos músculos flexores de punho e cinesioterapia nos músculos flexores e extensores de punho; e grupo B (GB): submetidos à estimulação elétrica nos músculos extensores de punho. A capacidade de preensão palmar foi avaliada por meio de um dinamômetro de bulbo antes, depois de 16 atendimentos e um mês após o término do tratamento. Os resultados demonstraram que houve aumento da capacidade de preensão palmar no GA (p=0,0244) e GB (p=0,0144) após o tratamento, com manutenção um mês após seu término (p=0,6002 e 0,3066 respectivamente), sem diferença estatística entre estes. Os achados apontam que ambos os recursos terapêuticos foram eficazes para o aumento da capacidade de preensão palmar dos participantes do estudo.


RESUMEN La espasticidad causada por el accidente cerebrovascular (ACV) es una de las principales causas de incapacidad funcional en el miembro superior. El objetivo del estudio fue verificar el efecto de la crioterapia asociada a la cinesioterapia y de la estimulación eléctrica en la capacidad de prensión palmar del miembro espástico de pacientes con ACV en fase crónica. Participaron del estudio 40 pacientes con edad media de 60,5 (±9,45) años y hemiparesia espástica, divididos aleatoriamente en grupo A (GA) -sometidos a la crioterapia en los músculos flexores del puño y cinesioterapia en los músculos flexores y extensores del puño - y grupo B (GB) - sometidos a la estimulación eléctrica en los músculos extensores del puño. Se evaluó la capacidad de prensión palmar por medio de un dinamómetro neumático antes del tratamiento, después de 16 atendimientos y un mes después del término del tratamiento. Los resultados demostraron un aumento de la capacidad de prensión palmar en el GA (p=0,0244) y en el GB (p=0,0144) después del tratamiento, con mantenimiento un mes después de su término (p=0,6002 y 0,3066 respectivamente), sin diferencia estadística entre éstos. Los hallazgos apuntan que ambos recursos terapéuticos fueron eficaces para aumentar la capacidad de prensión palmar de los participantes del estudio.


ABSTRACT Spasticity caused by stroke is a cause of functional disability of the upper extremity. The aim of this study was to check the effect of cryotherapy associated with kinesiotherapy and electrical stimulation on the palmar grip strength of the spastic limb of stroke patients in the chronic phase. Forty patients whose mean age was 60.5 (±9.45) years old and who had spastic hemiparesis participated in the study, having been randomly sorted into group A (GA): submitted to cryotherapy on the wrist flexors and kinesiotherapy on the wrist flexors and wrist extensors, and Group B (GB): submitted to electrical stimulation on the wrist extensors. Palmar grip strength was evaluated by a bulb dynamometer before, after 16 sessions and one month after the end of treatment. The results showed that there was an increase in palmar grip strength in GA (p=0.0244) and GB (p=0.0144) after treatment, with maintenance one month after its completion (p=0.6002 and 0.3066, respectively), and no statistical difference was observed between them. The findings indicate that both therapeutic resources were effective in increasing the study participants' palmar grip strength.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Cryotherapy , Electric Stimulation , Exercise Therapy , Muscle Spasticity/rehabilitation , Paresis/rehabilitation , Wrist Joint , Physical Therapy Modalities , Stroke/therapy
19.
Fisioter. Bras ; 20(1): 36-42, 20 de fevereiro de 2019.
Article in Portuguese | LILACS | ID: biblio-1281019

ABSTRACT

Objetivo: Foi avaliar os efeitos agudos da crioterapia na transferência de peso de pacientes hemiparéticos crônicos. Métodos: Estudo transversal composto por 52 pacientes, sendo 24 pacientes hemiparéticos crônicos e 28 pacientes saudáveis como controles. Utilizou-se a versão brasileira do Questionário de Waterloo para avaliar a preferência podal (WFQ-Brasil) para o grupo de pacientes-controle. Foram utilizadas duas balanças calibradas nas quais foi calculada a razão de simetria (lado parético/lado não parético) em pacientes hemiparéticos crônicos. Para o grupo controle, foi calculada uma razão de simetria (lado não dominante/lado dominante). Foi realizada a imersão do membro inferior acometido dos pacientes hemiparéticos e o lado dominante dos pacientes-controle em um balde com capacidade de 60 litros, com gelo e água, a uma temperatura aproximada de até 5ºC, sendo feita a avaliação pré-intervenção e imediatamente após. Resultados: Pôde-se observar diferença significativa na transferência de peso em ambos os grupos após a crioimersão. Conclusão: Conclui-se que a crioimersão por um perí­odo de 30 segundos com temperatura de até 5ºC foi suficiente para gerar alterações na transferência de peso para o lado parético resultando em alterações na simetria de sujeitos hemiparéticos crônicos, e nos controles, o comportamento foi similar com alterações na transferência de peso para a perna não dominante. (AU)


Aim: This study aims to evaluate the acute effects of cryotherapy immersion on weight transfer in chronic hemiparetic patients. Methods: The cross-sectional study was performed with 52 patients, 24 chronic hemiparetic and 28 healthy controls. The Brazilian version of the Waterloo Footedness Questionnaire (WFQ-Brazil) was used to evaluate the foot preference of the control group. Two calibrated balance were used to calculated in chronic hemiparetic patients with which the symmetry ratio (paretic side/non-paretic side), for the control group, a ratio of symmetry (non-dominant side/dominant side) was calculated. Immersion of the affected lower limb of the hemiparetic patients and the dominant side of the control patients was performed in a 60-litre bucket, with ice and water, at an approximate temperature of up to 5ºC, and immediately after this the pre-intervention evaluation was performed. Results: We observed a significant difference in weight transfer in both groups after cryo immersion. Conclusion: We concluded that the cryo immersion for a period of 30 seconds at a temperature of up to 5ºC was enough to generate changes in weight transfer, resulting in changes in the symmetry of chronic hemiparetic and control patients. (AU)


Subject(s)
Humans , Cryotherapy , Paresis , Stroke
20.
Article in English | WPRIM | ID: wpr-719614

ABSTRACT

BACKGROUND: Bronchoscopy is a useful diagnostic and therapeutic tool. However, the clinical use of high-flow nasal cannula (HFNC) in adults with acute respiratory failure for diagnostic and invasive procedures has not been well evaluated. We present our experiences of well-tolerated diagnostic bronchoscopy as well as cases of improved saturation in hypoxaemic patients after a therapeutic bronchoscopic procedure. METHODS: We retrospectively reviewed data of hypoxaemic patients who had undergone bronchoscopy for diagnostic or therapeutic purposes from October 2015 to February 2017. RESULTS: Ten patients (44–75 years of age) were enrolled. The clinical purposes of bronchoscopy were for diagnosis in seven patients and for intervention in three patients. For the diagnoses, we performed bronchoalveolar lavage in six patients. One patient underwent endobronchial ultrasonography with transbronchial needle aspiration of a lymph node to investigate tumour involvement. Patients who underwent bronchoscopy for therapeutic interventions had endobronchial mass or blood clot removal with cryotherapy for bleeding control. The mean saturation (SpO2) of pre-bronchoscopy in room air was 84.1%. The lowest and highest mean saturation with HFNC during the procedure was 95% and 99.4, respectively. The mean saturation in room air post-bronchoscopy was 87.4%, which was 3.3% higher than the mean room air SpO2 pre-bronchoscopy. Seven patients with diagnostic bronchoscopy had no hypoxic event. Three patients with interventional bronchoscopy showed improvement in saturation after the procedure. Bronchoscopy was well tolerated in all 10 cases. CONCLUSION: This study suggests that the use of HFNC in hypoxaemic patients during diagnostic and therapeutic bronchoscopy procedures has clinical effectiveness.


Subject(s)
Adult , Hypoxia , Bronchoalveolar Lavage , Bronchoscopy , Catheters , Cryotherapy , Diagnosis , Hemorrhage , Humans , Lymph Nodes , Needles , Oxygen , Respiratory Insufficiency , Retrospective Studies , Treatment Outcome , Ultrasonography
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