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1.
Rev. cir. traumatol. buco-maxilo-fac ; 22(4): 20-29, out.-dez. 2022. ilus, tab
Article in Portuguese | LILACS, BBO | ID: biblio-1414512

ABSTRACT

Objetivo: Avaliar os casos nos quais os pacientes apresentassem SVNP na ATM, incluindo aspectos clínicos, imaginológicos, histopatológicos e tratamento. Metodologia: Trata-se de uma revisão integrativa com dados obtidos nas bases de dados SciELO, PubMed, Medline e Lillacs entre 1982 e 2021, através dos descritores: "Case report", "Temporomandibular Joint", "Pigmented Villonodular Synovitis". Critérios de inclusão: estudos de relato de caso, textos completos disponíveis, idiomas de publicação em inglês, português ou espanhol. Critérios de exclusão: estudos sem presença de aspectos clínicos, relatos não localizados na ATM, artigos de metanálise, revisão sistemática e de literatura, ensaios clínicos, capítulos de livro, dissertações e teses. Dos 156 resultados, apenas 23 compuseram a revisão. Resultados: Como tratamento, a ressecção total através da cirurgia aberta é recomendada. Os sintomas mais comuns foram: dor na mastigação, trismo, dor pré auricular, dormência, parestesia, perca auditiva e inchaço da glândula parótida. Conclusão: Os aspectos imaginológicos revelam erosão de fossa glenóide e côndilo, histopatologicamente, células gigantes com depósito de hemossiderina, e o tratamento recomendado, ressecção via cirurgia aberta com posterior curetagem... (AU)


Objective: To evaluate the cases in which patients presented PVNS in the TMJ, including clinical, imaging, histopathological and treatment aspects. Methodology: This is an integrative review with data obtained from the SciELO, PubMed, Medline and Lillacs databases between 1982 and 2021, using the descriptors: "Case report", "Temporomandibular Joint", "Pigmented Villonodular Synovitis". Inclusion criteria: case report studies, full texts available, languages of publication in English, Portuguese or Spanish. Exclusion criteria: studies without the presence of clinical aspects, reports not located in the TMJ, meta analysis articles, systematic and literature reviews, clinical trials, book chapters, dissertations and theses. Of the 156 results, only 23 made up the review. Results: As a treatment, total resection through open surgery is recommended. The most common symptoms were: chewing pain, trismus, pre-auricular pain, numbness, paresthesia, hearing loss and parotid gland swelling. Conclusion: The imaging findings reveal erosion of the glenoid fossa and condyle, histopathologically, giant cells with hemosiderin deposits, and the recommended treatment, resection via open surgery with subsequent curettage... (AU)


Objetivo: Evaluar los casos en que los pacientes presentaron SVNP en la ATM, incluyendo aspectos clínicos, imagenológicos, histopatológicos y tratamiento. Metodología: Se trata de una revisión integradora con datos obtenidos de las bases de datos SciELO, PubMed, Medline y Lillacs entre 1982 y 2021, utilizando los descriptores: "Caso clínico", "Articulación temporomandibular", "Sinovitis villonodular pigmentada". Criterios de inclusión: estudios de casos clínicos, textos completos disponibles, idiomas de publicación en inglés, portugués o español. Criterios de exclusión: estudios sin aspectos clínicos, informes no localizados en la ATM, artículos de metanálisis, revisiones sistemáticas y de literatura, ensayos clínicos, capítulos de libros, disertaciones y tesis. De los 156 resultados, 23 conformaron la revisión. Resultados: Como tratamiento se recomienda la resección total mediante cirugía abierta. Los síntomas más frecuentes fueron: dolor masticatorio, trismus, dolor preauricular, entumecimiento, parestesia, hipoacusia e inflamación de glándula parótida. Conclusión: Los hallazgos imagenológicos revelan erosión de fosa glenoidea y cóndilo, histopatológicamente células gigantes con depósitos de hemosiderina y el tratamiento recomendado, resección abierta con posterior curetaje... (AU)


Subject(s)
Humans , Male , Female , Synovitis, Pigmented Villonodular/surgery , Temporomandibular Joint , Giant Cells , Synovitis, Pigmented Villonodular , Curettage , Glenoid Cavity
2.
Afr. J. reprod. Health (online) ; 26(12): 90-96, 2022. tables
Article in English | AIM | ID: biblio-1411776

ABSTRACT

Intrauterine adhesions (IUA) are rare. A retrospective comparative study was conducted between January 1, 2015, and December 31, 2018. Group A comprised 117 women who developed IUAs after open myomectomy, while Group B comprised 113 women who developed IUAs following uterine trauma caused by uterine instrumentation after a termination of pregnancy (TOP) or spontaneous miscarriage. The IUA grade and pregnancy rates and outcomes were compared using the March classification system. All patients underwent hysteroscopic adhesiolysis. The adhesions tended to be more severe (45/117, 38.5%) in Group A than in Group B (29/113, 25.7%); however, this difference was not statistically significant (Chi-Suare 5.047; p = .080). The period of observation was 24 months from the last hysteroscopy. The pregnancy rate in Group A (26, 22.2%) was significantly lower than in Group B (46, 40.7%) (OR: 2.403, 95% CI: 1.352­4.271; p = .003). Open myomectomy was the preceding aetiological factor in a greater proportion of women with IUA in our study. In cases where pregnancy is desired after open myomectomy, especially where the endometrial cavity is breached, postoperative hysteroscopy to exclude IUAs is recommended.


Subject(s)
Gynecologic Surgical Procedures , Tissue Adhesions , Pregnancy Rate , Curettage , Pregnancy , Hysteroscopy , Uterine Myomectomy , Gynatresia
3.
Rev. méd. Hosp. José Carrasco Arteaga ; 13(2): 100-106, 20-12-2021. tab
Article in Spanish | LILACS | ID: biblio-1352321

ABSTRACT

INTRODUCCIÓN: El cáncer de cuello uterino es un problema de salud pública, siendo una de las principales causas de morbilidad y mortalidad en países en vía de desarrollo. Para el screening y diagnóstico de las lesiones del cuello uterino se realiza citología cervical (Papanicolaou). Ante un reporte de citología sospechosa, la colposcopia es un procedimiento imprescindible en la evaluación del tracto genital inferior para detectar lesiones tempranas y cáncer. El objetivo de la presente investigación fue caracterizar los procedimientos colposcópicos realizados, como método diagnóstico y terapéutico, en las pacientes con resultados anormales del Papanicolaou. MATERIALES Y MÉTODOS: El presente es un estudio observacional, descriptivo de corte transversal, cuyo universo lo conformaron todas las pacientes con diagnóstico citológico anormal en Papanicolaou, que se realizaron un procedimiento colposcópico entre el año 2015 hasta el año 2019 en el Hospital José Carrasco Arteaga, con un total de 1 628 pacientes. RESULTADOS: Se incluyen 1 628 procedimientos colposcópicos. El 55.46% de la población estuvieron entre los 27 a 46 años de edad. El estado civil predominante fue casada (75%). El 63.45% de las mujeres iniciaron vida sexual entre los 21 a 30 años. El 95.20% de las pacientes tuvieron entre 1 y 3 parejas sexuales. Los resultados de Papanicolaou anormales representan; el 37.28% a LIE-BG, seguido de 35.81% con ASC-US y 14.18% como LIE-AG. El 67.32% de colposcopías fueron satisfactorias. Se realizó biopsia en el 71% de las pacientes, seguido de la toma de muestra de cono con ASA-LEEP (13.69%), legrado endocervical en el 11.05%. Los resultados de anatomía patológica reportaron LIE-AG en 46.56% de los casos, seguido de 22.23 % como LIE-BG y cervicitis crónica en el 16.27%, 12.28% de los resultados fueron negativos. CONCLUSIÓN: Tres cuartas partes de las colposcopias se realizaron en mujeres entre los 27 y 56 años de edad. Los resultados anormales más frecuentemente encontrados en el Papanicolaou fueron: LIE-BG, seguido de ASC-US. 67% de las colposcopias realizadas fueron satisfactorias. Tras la colposcopia, en la mayoría de pacientes se realizó biopsia, en un menor porcentaje y en orden de frecuencia: conización electro quirúrgica con asa (ASA-LEEP), legrado endocervical e histerectomía diagnóstica. Los resultados de anatomía patológica reportaron LIE-AG en el 46.56%, LIE-BG en el 22.23 % como y cervicitis crónica en el 16.27%; 12.28% de estudios fueron negativos.(au)


BACKGROUND: Cervical cancer is a public health issue, being one of the main causes of morbidity and mortality in developing countries. Cervical cytology (Papanicolaou) is performed for screening and diagnosis of cervical lesions. In case of a suspicious cytology report, colposcopy is an essential procedure for evaluation of the lower genital tract, to detect early lesions and cancer. The aim of this study was to characterize the colposcopy procedures performed, as a diagnostic and therapeutic method, in patients with abnormal Papanicolaou results. METHODS: This is an observational, descriptive cross-sectional study, whose universe were all the patients with abnormal cytological diagnosis in pap smear, who underwent a colposcopy procedure between 2015 and 2019 at Hospital José Carrasco Arteaga, with a total of 1 628 patients. RESULTS: 1 628 colposcopic procedures were included. 55.46% of the population were between 27 to 46 years of age. The predominant marital status was married status (75%). 63.45% of women had their first sexual experience between 21 and 30 years of age. 95.20% of the patients had between 1 and 3 sexual partners. Abnormal pap smear results represent; 37.28% to LSIL, followed by ASC-US (35.81%), and HSIL (14.18%). 67.32% of colposcopies were classified as satisfactory. Biopsy was performed in 71% of the patients, followed by loop electrosurgical excision procedure (LEEP) (13.69%), endocervical curettage in 11.05%. The pathology results reported HSIL in 46.56% of the cases, followed by 22.23% as LSIL and chronic cervicitis in 16.27%, 12.28% of the results were negative. CONCLUSION: Three-quarters of all colposcopies were performed on women between 27 and 56 years of age. The most frequently abnormal Pap smear results were: LSIL, followed ASC-US. 67% of the colposcopies were satisfactory. After colposcopy, biopsy was performed in most of the patients, in lower percentage: loop electrosurgical excision procedure (LEEP), endocervical curettage and diagnostic hysterectomy. Pathology results reported HSIL in 46.56%, LSIL IN 22.23% and chronic cervicitis in 16.27%; 12.28% of studies were negative.(au)


Subject(s)
Humans , Female , Adult , Middle Aged , Biopsy , Uterine Cervicitis , Uterine Cervical Neoplasms , Cervix Uteri , Colposcopy , Curettage
4.
Rev. chil. obstet. ginecol. (En línea) ; 86(5): 465-469, oct. 2021. ilus
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1388683

ABSTRACT

Resumen Reportamos el caso de una mujer de 28 años con atraso menstrual de 14 días, diagnosticada en el servicio de urgencia obstétrica del Hospital Félix Bulnes con un embarazo ectópico cervical mediante ultrasonido, en contexto de metrorragia grave. El tratamiento consistió en legrado uterino segmentario más ligadura de arterias cervicales. El estudio histopatológico reveló una mola hidatiforme parcial en el producto del curetaje. La paciente evolucionó favorablemente sin requerir más intervenciones. Este caso da cuenta del exitoso manejo de un embarazo cervical con tratamiento quirúrgico, dando una oportunidad de preservar la fertilidad de la paciente.


Abstract We are reporting the case of a 28-year-old woman with 14-day menstrual delay diagnosed, in the obstetric emergency department of Félix Bulnes Hospital, with a cervical pregnancy through ultrasound, in the context of severe metrorrhagia. The treatment consisted in uterine curettage and ligation of cervical arteries. A histopathological study revealed a partial hydatidiform mole in the curettage product. The patient evolved favorably without other interventions. This case its an example of the successful management of a cervical pregnancy with surgical treatment, giving a chance of preserving the fertility of the patient.


Subject(s)
Humans , Female , Pregnancy , Adult , Pregnancy, Ectopic/surgery , Pregnancy, Ectopic/diagnosis , Pregnancy, Ectopic/pathology , Hydatidiform Mole , Cervix Uteri , Curettage , Ligation
5.
Arch. argent. pediatr ; 119(1): e61-e64, feb. 2021. ilus
Article in Spanish | LILACS, BINACIS | ID: biblio-1147268

ABSTRACT

El osteoma osteoide es una lesión ósea benigna que, habitualmente, se acompaña de clínica típica caracterizada por dolor nocturno que mejora con antiinflamatorios no esteroideos. Aunque la presentación clínica es típica, con frecuencia, es común la demora diagnóstica, en especial, en los casos con localización atípica.Se presenta el caso de una paciente de 10 años con dolor en la muñeca izquierda de dos años de evolución con diagnóstico de osteoma osteoide localizado en el hueso grande del carpo. La localización atípica de la lesión conllevó un retraso diagnóstico importante


Osteoid osteoma is a benign bone lesion that is usually accompanied by a typical clinical condition characterized by night pain that improves with non-steroidal anti-inflammatory drugs. Although the clinical presentation is frequently typical, diagnostic delay is common, especially in cases with an atypical location.We report the case of a 10-year-old patient with left wrist pain of two years of evolution with diagnosis of osteoid osteoma located in capitate bone. The atypical location of the lesion led to a significant diagnostic delay.


Subject(s)
Humans , Female , Child , Osteoma, Osteoid/diagnostic imaging , Osteoma, Osteoid/surgery , Wrist , Curettage , Capitate Bone
6.
Article in Chinese | WPRIM | ID: wpr-887499

ABSTRACT

OBJECTIVE@#To observe the clinical therapeutic effect of the combination of electroacupuncture (EA) at @*METHODS@#A total of 58 patients after uterine curettage of incomplete abortion were randomized into an EA group and a western medication group, 29 cases in each one. In the western medication group, mifepristone tablets were administered orally, 2 tablets each time, once daily. In the EA group, on the base of the treatment as the western medication group, EA was applied to @*RESULTS@#After treatment, the intrauterine residue area and CDFI blood flow signal positive rate were all reduced as compared with the values before treatment in patients of the two groups (@*CONCLUSION@#The combined treatment of electroacupuncture at


Subject(s)
Abortion, Incomplete/therapy , Abortion, Induced , Acupuncture Points , Curettage , Electroacupuncture , Female , Humans , Pregnancy
7.
Rev. bras. ginecol. obstet ; 42(12): 800-804, Dec. 2020. tab, graf
Article in English | LILACS | ID: biblio-1156064

ABSTRACT

Abstract Objective In recent years, there has been an increase in the incidence of ectopic pregnancies; therefore, it is important for tertiary centers to report their approaches and outcomes to expand and improve treatment modalities. The aim of the present study was to evaluate the general characteristics, treatment and outcomes of cases diagnosed with ectopic pregnancy. Methods In total, 432 patients treated for ectopic pregnancy between February 2016 and June 2019 were retrospectively evaluated. Results Overall, 370 patients had tubal pregnancy, 32 had cesarean scar pregnancy, 18 had pregnancy of unknown location, 6 had cervical pregnancy, and 6 had interstitial pregnancy. The most important risk factors were advanced age (> 35 years; prevalence: 31.2%) and smoking (prevalence: 27.1%). Thirty patients who did not have any symptoms of rupture and whose human chorionic gonadotropin (β-hCG) levels were ≤ 200 mIU/ml were followed-up with expectant management, while 316 patients whose β-hCG levels were between 1,500 mIU/ml and 5,000 mIU/ml did not have an intrauterine gestational sac on the transvaginal or abdominal ultrasound, did not demonstrate findings of rupture, and were treated with a systemic multi-dose methotrexate treatment protocol. In total, 24 patients who did not respond to the medical treatment, 20 patients whose β-hCG levels were > 5,000 mIU/ml, 16 patients who had shown symptoms of rupture at the initial presentation, and 6 patients diagnosed with interstitial pregnancy underwent surgery. Patients with cervical and scar pregnancies underwent ultrasound-guided curettage, and no additional treatment was needed. Conclusion The fertility status of the patients, the clinical and laboratory findings, and the levels of β-hCG are the factors that must be considered in planning the appropriate treatment.


Subject(s)
Humans , Female , Pregnancy , Adolescent , Adult , Young Adult , Pregnancy, Ectopic/epidemiology , Ultrasonography, Prenatal , Pregnancy, Ectopic/etiology , Pregnancy, Ectopic/therapy , Pregnancy, Ectopic/diagnostic imaging , Brazil/epidemiology , Abortifacient Agents, Nonsteroidal/therapeutic use , Methotrexate/therapeutic use , Retrospective Studies , Risk Factors , Treatment Outcome , Curettage , Tertiary Care Centers , Middle Aged
8.
Más Vita ; 2(3): 90-101, sept 2020. ilus
Article in Spanish | LILACS, LIVECS | ID: biblio-1367693

ABSTRACT

Las infecciones cuando pasan a ser crónicas y recurrentes como puede ser el caso de una pericoronaritis medicada, mas no tratada una y otra vez, traen como consecuencia resistencia y proliferación bacteriana. Se da el caso de formaciones de tejidos patológicos e imágenes radiográficas que orientan a posibles diagnósticos, que hasta no ser tratadas por medio de diferentes técnicas como la marsupialización o enucleación, con el complemento de la biopsia insicional o exicional que determina el tipo de patología presente. Esto lleva al objetivo general: determinar el tipo de lesión patológica presente en el ángulo y cuerpo mandibular asociado a la ud: 48 Objetivos específicos: Identificar la lesión patológica presente en Angulo y parte del cuerpo mandibular asociada a la ud: 48. Muestra: paciente de 30 años de edad, masculino, caso clínico de una inflamación mixta severa, la clínica y sus hallazgos radiográficos, se sospechaba de un posible queratoquiste, quiste dentígeros o quiste odontogénico ortoqueratinizado, extracción dental ud: 48, retiro y legrado del tejido circundante, toma de biopsia exicional, exámenes de laboratorio, ortopantomografia, tomografía, fotografías clínicas. Metodología: paradigma positivista, enfoque cuantitativo, diseño no experimental. Modalidad de campo, tipo estudio de caso. La entrevista, el instrumento guión de las preguntas para la historia clínica fueron la técnica y el instrumento. Resultados: inflamación mixta severa, lo cual procede de una infección asociada a pericoronaritis recurrente, esto mediante resultado histopatológico. Conclusiones: el estudio histopatológico es quien determina el diagnóstico final a pesar que la clínica induzca a posibles diagnósticos diferenciales(AU)


When infections become chronic and recurrent, such as a medicated pericoronitis, but not treated repeatedly, they result in resistance and bacterial proliferation. There is the case of pathological tissue formations and radiographic images that guide possible diagnoses, which until they are not treated by means of different techniques such as marsupialization or enucleation, with the complement of the incitional or exicional biopsy that determines the type of pathology present. This leads to the general objective: to determine the type of pathological lesion present in the mandibular angle and body associated with ud: 48. Specific objectives: Identify the pathological lesion present in Angle and part of the mandibular body associated with ud: 48. Sample: 30-year-old male patient, clinical case of severe mixed inflammation, clinical symptoms and radiographic findings, suspected of a possible keratocyst, dentigerous cyst or orthokeratinized odontogenic cyst, tooth extraction ud: 48, removal and curettage of the surrounding tissue, exicional biopsy, laboratory tests, orthopantomography, tomography, clinical photographs. Methodology: positivist paradigm, quantitative approach, non-experimental design. Field modality, case study type. The interview, the instrument script the questions for the clinical history were the technique and the instrument. Results: severe mixed inflammation, which comes from an infection associated with recurrent pericoronitis, this through histopathological result. Conclusions: the histopathological study is the one who determines the final diagnosis, despite the fact that the symptoms lead to possible differential diagnoses(AU)


Subject(s)
Humans , Male , Adult , Odontogenic Cysts , Soft Tissue Infections/diagnosis , Curettage , Mouth/anatomy & histology , Surgery, Oral , Tooth Extraction , Radiography, Panoramic , Prevalence , Tooth Crown
9.
Rev. chil. obstet. ginecol. (En línea) ; 85(4): 324-334, ago. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1138628

ABSTRACT

INTRODUCCIÓN Y OBJETIVOS: En Chile, existen datos parcializados en cuanto a la prevalencia de aborto. La población migrante ha generado un cambio en las características de las pacientes en situación de aborto. El objetivo es describir las características demográficas y clínicas de las mujeres con aborto de manejo quirúrgico con y sin complicaciones. MÉTODOS: Estudio Descriptivo Transversal. Se incluyeron mujeres atendidas por aborto, sometidas a método de evacuación y que estuvieran ingresadas al sistema SIP/CLAP. Se compararon mujeres con o sin complicaciones con respecto a diferentes características demográficas y clínicas. Se calculó Odd Ratio para algunas variables de interés. RESULTADOS: Se incluyeron 554 mujeres, un 13% (N= 73) tuvo complicación al ingreso, principalmente hemorrágica (40%). Las características demográficas fueron similares en ambos grupos. Hubo mayor riesgo de complicación en mujeres con abortos previos (OR: 2,4 (IC 1,3-4,5), p =0.00), cuando el diagnóstico de ingreso fue aborto incompleto (OR: 85,3 (IC 25,2-288), p=0,00) y cuando se realizó legrado (OR: 4 (IC 2,5-6,5) p=0,00). La mayoría de las pacientes con complicaciones no planeó el embarazo (OR: 11 (IC 3,4-37,7), p=0,00) y no usó método anticonceptivo en esta gestación. El 70% recibió método anticonceptivo al egreso. CONCLUSIONES: Existen características clínicas asociadas a complicación en mujeres con aborto de manejo quirúrgico en nuestro centro, como diagnóstico de ingreso, embarazo no planificado, aborto previo y tipo de evacuación. Existen limitaciones en cuanto a la cantidad y calidad de información, sin embargo, nuestros resultados permiten conocer el perfil de pacientes atendidas por aborto en nuestro centro.


INTRODUCTION AND OBJECTIVES: In Chile, there are partial data regarding the prevalence of abortion. The migrant population has generated a change in the characteristics of patients in an abortion situation. The objective is to describe the demographic and clinical characteristics of women with surgical abortion with and without complications. METHODS: Transversal Descriptive Study. Women treated for abortion, undergoing evacuation method and who were admitted to the SIP / CLAP system were included. Women with or without complications were compared with respect to different demographic and clinical characteristics. Odd Ratio was calculated for some variables of interest. RESULTS: 554 women were included, 13% (N = 73) had complication at admission, mainly hemorrhagic (40%). Demographic characteristics were similar in both groups. There was an increased risk of complication in women with previous abortions (OR: 2.4 (IC 1.3-4.5), p = 0.00), when the diagnosis of admission was incomplete abortion (OR: 85.3 (IC 25.2- 288), p = 0.00) and when curettage was performed (OR: 4 (IC 2.5-6.5) p = 0.00). The majority of patients with complications did not plan pregnancy (OR: 11 (IC 3.4-37.7), p = 0.00) and did not use a contraceptive method in this pregnancy. 70% received contraceptive method upon discharge. CONCLUSIONS: There are clinical characteristics associated with complications in women with surgical management abortion in our center, such as admission diagnosis, unplanned pregnancy, previous abortion and type of evacuation. There are limitations regarding the quantity and quality of information, however, our results allow us to know the profile of patients treated for abortion in our center.


Subject(s)
Humans , Female , Pregnancy , Adult , Young Adult , Abortion, Spontaneous/surgery , Medical Records Systems, Computerized , Curettage , Postoperative Complications , Transients and Migrants , Strategic Evacuation , Comorbidity , Abortion, Spontaneous/epidemiology , Chile , Epidemiology, Descriptive , Cross-Sectional Studies , Educational Status
10.
Rev. cir. traumatol. buco-maxilo-fac ; 20(2): 30-34, abr.-jun. 2020. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-1253481

ABSTRACT

Introdução:As lesões fibro-ósseas constituem-se num grupo de lesões caracterizadas por processos de substituição de osso normal por tecido fibroso contendo material mineralizado.O fibroma ossificante juvenil é uma neoplasia fibro-óssea benigna que acomete indivíduos jovens, de comportamento agressivo local e com altas taxas de recidiva. São relatadas duas variantes denominadas de fibroma ossificante juvenil trabecular (FOJT) e o fibromaossificante juvenil psamomatoide (FOJP). Apesar de ambos os padrões demonstrarem características semelhantes, a predileção para idade e os sítios de acometimento sãoespecíficos.O tratamento indicado varia de enucleção e curetagem à ressecção cirúrgica. Este trabalho tem como objetivo relatar um caso de um paciente portador de Fibroma Ossificante Juvenil na maxila. Relato de caso: J.S.B., 18 anos, sexo masculino, procurou o Serviço de Cirurgia e Traumatologia Bucomaxilofacial do Hospital Getúlio Vargas, em Recife/PE, com queixa de "caroço no rosto" com aproximadamente 5 anos de evolução em maxila direita. Paciente foi submetido ao tratamento cirúrgico conservador mediante enucleação, curetagem e osteotomia periférica e está sendo acompanhado há cerca de 10 meses sem apresentar recidiva. Considerações finais: O tratamento mais conservador escolhido foi considerado de sucesso, efetivo, com mínimo de morbidade. Mas, devido à lesão ser considerada agressiva e por possuir alta taxa de recidivas, necessita-se de longo período de acompanhamento... (AU)


Introduction: Fibro-osseous lesions constitute a group of lesions characterized by processes of replacement of normal bone by fibrous tissue containing mineralized material. Juvenile Ossifying Fibroma is a benign fibro-osseous neoplasm that affects young individuals, local aggressive behavior, with high rates of relapse. Two variants named trabecular juvenile ossifying fibroma (TJOF) and psamomatoid juvenile ossifying fibroma (PJOF) are reported. Although both patterns demonstrate similar characteristics, the predilection for age and the sites of involvement are specific. The indicated treatment varies from enucleation and curettage to surgical resection. This article aims to report a case of a patient with juvenile ossifying fibroma in maxilla.Case report:J.S.B., 18 years old, male, sought the Surgery and Traumatology Service of Hospital Getúlio Vargas, Recife / PE, complaining of a "lump in the face" with approximately 5 years of evolution in right maxila. Patient underwent conservative surgical treatmentwas performed through enucleation, curettage and peripheral osteotomy and has been followed for about 10 months without recurrence.Final considerations: The most conservative treatment chosen was considered successful, effective, with minimal morbidity. However, because the injury is considered aggressive and because it has a high rate of recurrence, a long follow-up period is required... (AU)


Subject(s)
Humans , Male , Adolescent , Wounds and Injuries , Fibroma, Ossifying , Face , Maxilla , Neoplasms , Osteotomy , Bone and Bones , Traumatology , Curettage
11.
Braz. j. otorhinolaryngol. (Impr.) ; 86(1): 38-43, Jan.-Feb. 2020. tab
Article in English | LILACS | ID: biblio-1089367

ABSTRACT

Abstract Introduction Adenoidectomy can be performed with many ways, including curettage and microdebrider endoscopic-assisted adenoidectomy. Those two techniques have advantages and disadvantages. Objective The objective of this study is to research the effects of curettage adenoidectomy and endoscopic-assisted microdebrider adenoidectomy on the tympanum pressures in pediatric patients with adenoid hypertrophy without otitis media with effusion. Methods This prospective descriptive study was performed with 65 patients who had a normal tympanic membrane and normal tympanogram and then underwent adenoidectomy or adenotonsillectomy for adenoid and tonsil hypertrophy. The subjects were randomly divided into two groups: curettage adenoidectomy group and endoscopic microdebrider-assisted adenoidectomy group. They underwent tympanometry, and the preoperative as well as 1st and 7th day postoperative values of the tympanum pressures were compared within and among the groups. Results There were 32 patients in the curettage adenoidectomy group and 33 patients in the microdebrider adenoidectomy group. Statistically significant differences were observed in the median tympanum pressure on the preoperative and 1st and 7th postoperative days for both the left and right ears with curettage adenoidectomy (p < 0.001, p < 0.001). This difference occurred on the 1st postoperative day, and the value returned to normal on the 7th day. There was no significant difference in the median tympanum pressure on the preoperative and 1st and 7th postoperative days for both the left and right ears in the microdebrider adenoidectomy group (p = 0.376, p = 0.128). Conclusion Postoperative Eustachian tube dysfunction is seen less often with the endoscopic-assisted microdebrider adenoidectomy technique than with the conventional adenoidectomy technique.


Resumo Introdução A adenoidectomia pode ser realizada de várias maneiras, inclusive por curetagem e por microdebridador, assistida por endoscopia. Essas duas técnicas têm algumas vantagens e desvantagens. Objetivo O objetivo deste estudo foi investigar os efeitos da técnica de adenoidectomia por curetagem e da adenoidectomia por microdebridador assistida por endoscopia sobre a pressão timpânica em pacientes pediátricos com hipertrofia adenoideana sem otite média com efusão. Método Estudo descritivo prospectivo feito com 65 pacientes que apresentavam membrana timpânica e timpanograma normais, que foram então submetidos à adenoidectomia ou adenotonsilectomia por hipertrofia adenoamigdaliana. Os pacientes foram divididos aleatoriamente em dois grupos: grupo adenoidectomia por curetagem e grupo adenoidectomia por microdebridador assistida por endoscópio. Todos os pacientes fizeram timpanometria e os valores das pressões do tímpano pré-operatórios e pós-operatórios no 1º e 7º dias foram comparados intragrupos e entre os grupos. Resultados Foram incluídos 32 pacientes no grupo adenoidectomia por curetagem e 33 pacientes no grupo adenoidectomia com microdebridador. Diferenças estatisticamente significantes foram observadas na mediana da diferença entre a pressão timpânica no pré-operatório e no 1º e 7º dias de pós-operatório para ambas as orelhas, direita e esquerda, na adenoidectomia por curetagem (p < 0,001, p < 0,001). Essa diferença ocorreu no 1º dia do pós-operatório e o valor retornou ao normal no 7º dia. Não houve diferença significante na mediana entre pressão timpânica no pré-operatório e no 1º e 7º dias de pós-operatório para as orelhas direita e esquerda no grupo de adenoidectomia com microdebridador (p = 0,376, p = 0,128). Conclusão A disfunção tubária no pós-operatório é observada menos frequentemente com a técnica de adenoidectomia por microdebridador assistida por endoscopia quando comparada com a técnica convencional.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adenoidectomy/methods , Curettage/methods , Eustachian Tube/physiopathology , Postoperative Period , Pressure , Acoustic Impedance Tests , Single-Blind Method , Prospective Studies , Treatment Outcome , Video-Assisted Surgery/methods , Debridement/methods , Ear, Middle/physiopathology
12.
Article in Chinese | WPRIM | ID: wpr-827512

ABSTRACT

Decompression and curettage can result are effective as treatments for large jaw cysts, which are common diseases in the clinic. Based on a treatment used in a previous study, this paper proposes a "three-step method" to treat large jaw cyst and repair the bone defect by decompression, curettage, and autologous dental bone powder implantation. This paper introduces the processes and key points of the operation involved in the abovementioned method.


Subject(s)
Bone Cements , Bone Cysts , General Surgery , Bone Transplantation , Curettage , Humans , Jaw Cysts
13.
DST j. bras. doenças sex. transm ; 31(4): 123-130, 31-12-2019.
Article in English | LILACS | ID: biblio-1122027

ABSTRACT

Introduction: Syphilis is an infectious disease caused by Treponema pallidum, its two main routes of transmission are sexual and transplacental (vertical). The latter is of particular worrisome, since it can generate congenital syphilis and can be avoided by early maternal serological screening. Objective: To analyze the conditions of prenatal care for syphilitic pregnant women in Sergipe State between 2007 and 2019. Methods: A cross-sectional, retrospective, and descriptive study was carried out, with the collection of notified cases of gestational and congenital syphilis in the Brazilian Notifiable Diseases Information System (Sistema de Informação de Agravos de Notificação - SINAN). Results: There was a considerable increase in the number of reported cases of gestational syphilis in the last 13 years. About 36% of pregnant women were identified in the 3rd trimester of pregnancy, 68.1% were brown, 56.8% had studied for up to 8 years, and 50.1% were between 20 and 29 years old. The clinical phase latent to the diagnosis was responsible for 70.3% of the cases, followed by the primary (11%) and tertiary (7.3%) phases. Of the total number of pregnant women, 20.2% did not perform the non-treponemal test, and 97.2% were treated with penicillin. Regarding the numbers of congenital syphilis, although 75% of the mothers performed prenatal care, 37.8% received the diagnosis at the time of delivery/curettage, resulting in 72.9% of infant deaths from the disease. Moreover, there was a predominance of untreated partners (77.7%) in relation to those treated (10.8%). Conclusion: Although most of them performed prenatal care, there was a predominance of diagnoses performed only in the 3rd trimester of pregnancy, mainly at the time of delivery or curettage, not respecting the minimum therapeutic interval of 30 days before delivery. Thus, in Sergipe State, the most important factor in the high prevalence of vertical transmission of syphilis is the ineffectiveness of prenatal care provided to infected pregnant women, which remains.


Introdução: a sífilis é uma doença infecciosa causada pelo Treponema pallidum, suas duas principais vias de transmissão são a sexual e a transplacentária (vertical). Este último é particularmente preocupante, pois pode gerar sífilis congênita e pode ser evitado por meio de triagem sorológica materna precoce. Objetivo: Analisar as condições da assistência pré-natal para gestantes sifilíticas no estado de Sergipe entre 2007 e 2019.Métodos: Foi realizado um estudo transversal, retrospectivo e descritivo, com coleta de casos notificados de sífilis gestacional e congênita no Sistema de Informação de Agravos de Notificações (SINAN). Resultados: Houve um aumento considerável no número de casos notificados de sífilis gestacional nos últimos 13 anos. Cerca de 36% das gestantes foram diagnosticadas no 3º trimestre da gestação, 68,1% eram pardas, 56,8% haviam estudado até 8 anos e 50,1% tinham entre 20 e 29 anos. A fase clínica latente ao diagnóstico foi responsável por 70,3% dos casos, seguida das fases primária (11%) e terciária (7,3%). Do total de gestantes, 20,2% não realizaram o teste não treponêmico e 97,2% foram tratadas com penicilina. Em relação aos números de sífilis congênita, embora 75% das mães realizassem o pré-natal, 37,8% receberam o diagnóstico no momento do parto/curetagem, resultando em 72,9% dos óbitos infantis pela doença. Além disso, houve predomínio de parceiros não tratados (77,7%) em relação aos tratados (10,8%).Conclusão: Apesar de a maioria das gestantes realizar o prénatal, houve predomínio de diagnósticos realizados apenas no 3º trimestre da gestação, principalmente no momento do parto ou curetagem, não respeitando o intervalo terapêutico mínimo de 30 dias antes do parto. Assim, no estado de Sergipe, o fator mais importante na alta prevalência da transmissão vertical da sífilis é a ineficácia da assistência pré-natal prestada às gestantes infectadas, que permanece.


Subject(s)
Humans , Syphilis, Congenital , Disease Transmission, Infectious , Pregnant Women , Prenatal Care , Communicable Diseases , Curettage
14.
Rev. bras. ortop ; 54(6): 714-720, Nov.-Dec. 2019. tab, graf
Article in English | LILACS | ID: biblio-1057963

ABSTRACT

Abstract Objective Enchondromas are the commonest tumors of the bones of the hand. Treatment approaches vary. The present article presents the characteristics of the tumors, diagnostic methods, and treatments. Methods We discuss the approach used in our institution, where we have treated 48 patients with enchondromas of the hand between 1996 and 2016. Our technique of treatment, which has remained the same over 2 decades, comprises the use of curettage, high-speed burr, and autologous bone graft (harvested with a minimally invasive technique, using a Craig biopsy needle). Results Pain and fractures were the most common symptoms leading the patients to consultation, at frequencies of 33.3% and 31.3%, respectively. A total of 27.1% of the cases were asymptomatic, and their lesions were discovered incidentally. The mean age was 34.4 years (SD = 12.9 years). Tumors were more frequently presented in the ulnar side of the hand, in the fifth ray (41.5%) and in the proximal bones (in the proximal phalanges [43.8%], and in the metacarpal [33.3%]). The size of the tumors ranged from 0.2 cm2 to 5.7 cm2, with a mean of 1.7 cm2 (standard deviation [SD] = 1.0 cm2) and were not associated with fracture (p = 0.291). Fracture was also not associated with any of the symptoms, neither with the age of the patients (p = 0.964). After the treatment, most patients achieved full range of motion (91.7%), with good integration of the bone graft. Three patients presented deficit in range of motion (6.3%) and the incidence of complications was also 6.3% (3 patients). At the end, after the needed surgical revisions, these three patients also recovered full function. They achieved full bone graft integration, regained full range of motion and returned to work. There was no tumor recurrence case during the follow-up period evaluated. For all cases, no donor site complications occurred. Conclusion Our method of treatment has consistently provided good outcomes, with only a few minor complications. Therapeutic level of evidence: IV.


Resumo Objetivo Os encondromas são os tumores mais comuns dos ossos da mão, com uma grande variedade de abordagens terapêuticas. O presente artigo apresenta as características dos tumores, métodos diagnósticos e tratamentos. Métodos Discutimos a abordagem da nossa instituição, onde tratamos 48 pacientes com encondromas da mão, entre 1996 e 2016. Nossa técnica de tratamento, que permanece a mesma ao longo de duas décadas, compreende o uso de curetagem, esmeril de velocidade e enxerto ósseo autólogo (retirado com uma técnica minimamente invasiva, usando uma agulha de Craig). Resultados A dor e as fraturas foram os sintomas mais comuns, levando os pacientes à consulta, nas frequências de 33,3% e 31,3%, respectivamente. Um total de 27,1% dos casos era assintomático, e suas lesões foram descobertas incidentalmente. A média de idade foi de 34,4 anos (desvio padrão [DP] = 12,9 anos). Os tumores foram mais frequentemente encontrados no lado ulnar da mão, no quinto raio (41,5%), e nos ossos proximais (nas falanges proximais [43,8%] e no metacarpo [33,3%]). O tamanho do tumor variou de 0,2 cm2 a 5,7 cm2, com média de 1,7 cm2 (DP = 1,0 cm2) e não foi associado à fratura (p = 0,291). A fratura também não foi associada a nenhum dos sintomas, e nem à idade dos pacientes (p = 0,964). Após o tratamento, a maioria dos pacientes alcançou amplitude completa de movimento (91,7%), com boa integração do enxerto ósseo. Três pacientes apresentaram déficit no arco de movimento (6,3%) e a incidência de complicações também foi de 6,3% (3 pacientes). No final, após as revisões cirúrgicas necessárias, esses três pacientes também recuperaram a função completa. Eles tiveram a integração total do enxerto ósseo, recuperaram toda a amplitude de movimento e retornaram ao trabalho. Não houve nenhum caso de recorrência do tumor durante o período de acompanhamento avaliado. Em nenhum dos casos ocorreram complicações no local doador. Conclusão O nosso método de tratamento forneceu consistentemente bons resultados, com apenas algumas complicações menores. Nível terapêutico de evidência: IV.


Subject(s)
Humans , Male , Female , Adult , Pain , Biopsy , Bone and Bones , Chondroma , Bone Transplantation , Curettage , Hand Bones , Fractures, Bone , Hand , Neoplasms
15.
Rev. colomb. obstet. ginecol ; 70(4): 277-292, oct.-dic. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1093050

ABSTRACT

RESUMEN Objetivos: reportar el caso de un embarazo cervical (EC) que recibió manejo conservador exitoso y realizar una revisión de la literatura sobre el tratamiento médico y quirúrgico conservador. Materiales y métodos: se presenta el caso de una paciente con embarazo cervical, quien recibió manejo farmacológico con metotrexate (MTX) y posterior legrado con evolución clínica satisfactoria. Se realizó una búsqueda de artículos en Medline vía PubMed, LILACS, SciElo y Google académico con los términos: "cervical ectopic pregnancy", "conservative treatment", "curettage", "methotrexate", "uterine artery embolization" "hysteroscopy". Se seleccionaron reportes y series de caso, pacientes con embarazo cervical diagnosticado por ultrasonido, de cualquier edad gestacional, sometidas tratamiento médico o quirúrgico conservador. Resultados: se incluyeron 22 estudios; se identificaron 95 pacientes con EC tratados con MTX, con tratamiento exitoso en 93. La complicación más frecuente fue la hemorragia en 12 %; el 26 % requirió tratamiento quirúrgico complementario. Cada vez más, la embolización de arterias uterinas (EAU) se realiza de manera preventiva (7 casos) antes del legrado o del tratamiento con MTX. La histeroscopia es otra alternativa reciente (20 casos). En 2 casos se requirió histerectomía abdominal, uno de los cuales fue un embarazo ístmico cervical. Conclusiones: el tratamiento con MTX sigue siendo el más frecuentemente utilizado. La dilatación y el curetaje con taponamiento endocervical puede ser una opción por considerar en el manejo de urgencia del EC en instituciones de atención primaria. En instituciones donde se dispone de tecnologías de alta complejidad, la embolización de arterias uterinas previa a los procedimientos quirúrgicos y la histeroscopia son opciones que se deben considerar. Dado que actualmente es posible el diagnóstico temprano del EC, se requieren estudios multicéntricos que comparen las diferentes alternativas de manejo para una mejor evaluación de su seguridad y efectividad. Conclusiones: el tratamiento con MTX sigue siendo el más frecuentemente utilizado. La dilatación y el curetaje con taponamiento endocervical puede ser una opción por considerar en el manejo de urgencia del EC en instituciones de atención primaria. En instituciones donde se dispone de tecnologías de alta complejidad, la embolización de arterias uterinas previa a los procedimientos quirúrgicos y la histeroscopia son opciones que se deben considerar. Dado que actualmente es posible el diagnóstico temprano del EC, se requieren estudios multicéntricos que comparen las diferentes alternativas de manejo para una mejor evaluación de su seguridad y efectividad


ABSTRACT Objectives: To report a case of cervical pregnancy (CP) treated successfully with a conservative approach, and to conduct a review of the literature regarding conservative medical and surgical treatment. Materials and Methods: Patient with cervical pregnancy treated pharmacologically with methotrexate (MTX) followed by dilation and curettage, with a satisfactory clinical course. A search of articles was conducted in Medline via PubMed, LILACS, SciElo and Google Scholar using the terms "cervical ectopic pregnancy," "conservative treatment," "curettage,¼ "methotrexate," "uterine artery embolization," "hysteroscopy." Reports and case series were selected of patients with cervical pregnancy diagnosed on ultrasound at any gestational age, subjected to conservative medical or surgical treatment. Results: A total of 22 studies were included; 95 patients with CP treated with MTX were identified, 93 of them successfully treated. The most frequent complication was bleeding in 12%; 26% required complementary surgical treatment. Increasingly, uterine artery embolization (UAE) is carried out preventatively (7 cases) before curettage or treatment with MTX. The hysteroscopy is another recent alternative (20 cases). Abdominal hysterectomy was required in two cases, one of which was a cervico-isthmic pregnancy. Conclusions: Treatment with MTX continues to be the most frequent strategy. Dilation and curettage with endocervical plugging may be an option to consider in the emergency management of EP in primary care institutions. In institutions equipped with high complexity technology, uterine artery embolization before the surgical procedure and histeroscopy are options to be considered. Considering that early diagnosis of EP is now possible, multi-center studies comparing different management options are needed for better assessment of their safety and effectiveness.


Subject(s)
Humans , Female , Pregnancy , Conservative Treatment , Pregnancy, Ectopic , Curettage , Fertility , Chorionic Gonadotropin
16.
Rev. cuba. obstet. ginecol ; 45(3): e371, jul.-set. 2019.
Article in Spanish | LILACS, CUMED | ID: biblio-1093665

ABSTRACT

RESUMEN El antecedente de cesáreas es el factor de riesgo más importante en el desarrollo de los trastornos del espectro de placenta acreta. La elevación global del indicador de cesárea ha llevado aparejado un aumento en la incidencia de estos trastornos. Sin embargo, deben considerarse entre los riesgos, otras condiciones antenatales asociadas con un daño quirúrgico menos extenso de la pared uterina, tal es el caso de los legrados. Se realiza una revisión de la literatura sobre el tema de los trastornos del espectro de placenta acreta para profundizar sobre su grave repercusión en el embarazo y se recomienda, como parte de la atención prenatal, la pesquisa de placentación acreta en toda gestante con antecedentes de legrados uterinos. La placenta acreta es casi siempre una condición enteramente iatrogénica y en lo que respecta al aborto, profesionales de la salud y paciente podríamos contribuir a la disminución de su incidencia(AU)


ABSTRACT A history of C-sections is the most important risk factor for the development of placenta accreta spectrum disorders. The global elevation of caesarean section indicator has led to increase the incidence of these disorders. However, other antenatal conditions should be considered among the risks, associated with less extensive surgical damage of the uterine wall, such as curettage. A literature review on the subject of placental accreta spectrum disorders is carried out to deepen on the serious impact on pregnancy. Screening of placenta accreta is recommended in all pregnant women with a history of uterine curettage, as part of prenatal care. Placenta accreta is generally an entirely iatrogenic condition. Health professionals and patients could contribute to the reduction of this condition incidence, in regards to abortion(AU)


Subject(s)
Humans , Female , Pregnancy , Placenta Accreta/epidemiology , Prenatal Care/trends , Risk Factors , Curettage/methods , Review Literature as Topic
17.
Article in English | WPRIM | ID: wpr-739484

ABSTRACT

BACKGROUND: Fracture–dislocation of the proximal interphalangeal (PIP) joint of the finger is challenging due to the high risk of stiffness. The purpose of this study is to evaluate the clinical and radiological results of a modified transosseous wiring technique for the management of chronic fracture–dislocations of the PIP joint. METHODS: Ten patients (nine men and one woman; mean age, 38.3 years; range, 21 to 69 years) with neglected fracture–dislocation of the PIP joint were included. The mean duration from injury to operation was 14.7 weeks (range, 3 to 66 weeks). The dorsolateral approach and extension block pinning were used to reduce dislocation. After thorough debridement of the scar tissues in the dorsal dead space and the fracture site, the reduction was maintained with transosseous wiring. Radiologic evaluations of bone union and arthritic changes and clinical evaluations (range of motion of the PIP joint and Disabilities of the Arm, Shoulder and Hand [DASH] score) were performed. The mean follow-up period was 12.9 months (range, 12 to 19 months). RESULTS: All patients demonstrated evidence of radiographic healing within a mean healing time of 6 weeks (range, 4 to 10 weeks); however, one had a widened gap and one had an early arthritic change. The mean range of motion in the PIP joint was 81° (range, 50° to 105°). The mean DASH score was 21.6 (range, 7.5 to 35.8). CONCLUSIONS: For chronic fracture–dislocation of the PIP joint, transosseous wiring with direct curettage and optimal bone purchase can provide satisfying outcome.


Subject(s)
Arm , Bone Wires , Cicatrix , Curettage , Debridement , Joint Dislocations , Female , Fingers , Follow-Up Studies , Hand , Humans , Joints , Male , Range of Motion, Articular , Shoulder
18.
Article in English | WPRIM | ID: wpr-766313

ABSTRACT

OBJECTIVES: Osteoradionecrosis (ORN) is one of the most severe complications resulting from radiotherapy (RT) in patients with head and neck cancer (HNC). It is characterized by persistent exposed and devitalized bone without proper healing for greater than 6 months after a high dose of radiation in the area. To describe the profile and dental management of ORN in HNC patients undergoing RT in an oncological clinical research center. MATERIALS AND METHODS: A retrospective descriptive study was performed to analyze dental records from HNC patients with ORN treated at an oncological clinical research center from 2013 to 2017. A total of 158 dental records for HNC patients were selected from a total of 583 records. Afterwards, this number was distributed to three examiners for manual assessments. Each examiner was responsible for selecting dental records that contained an ORN description, resulting in 20 dental records. RESULTS: Mean patient age was 60.3 years with males being the most affected sex (80.0%). The most affected area was the posterior region of the mandible (60.0%) followed by the anterior region of the mandible (20.0%) and the posterior region of the maxilla (10.0%). The factors most associated with ORN were dental conditions (70.0%) followed by isolated systemic factors (10.0%) and tumor resection (5.0%). There was total exposed bone closure in 50.0% of cases. The predominant treatment was curettage associated with chlorhexidine 0.12% irrigation (36.0%). CONCLUSION: Poor dental conditions were related to ORN occurrence. ORN management through less invasive therapies was effective for the closure of exposed bone areas and avoidance of infection.


Subject(s)
Chlorhexidine , Curettage , Dental Records , Head and Neck Neoplasms , Head , Humans , Jaw , Male , Mandible , Maxilla , Osteoradionecrosis , Radiotherapy , Retrospective Studies
19.
Article in Korean | WPRIM | ID: wpr-764826

ABSTRACT

PURPOSE: To evaluate the efficacy of antibiotic-loaded cement spacers (ALCSs) for the treatment of diabetic foot infections with osteomyelitis as a salvage procedure and to analyze the risk factors of treatment failure. MATERIALS AND METHODS: This study reviewed retrospectively 39 cases of diabetic foot infections with osteomyelitis who underwent surgical treatment from 2009 to 2017. The mean age and follow-up period were 62±13 years and 19.2±23.3 months, respectively. Wounds were graded using the Wagner and Strauss classification. X-ray, magnetic resonance imaging (or bone scan) and deep tissue cultures were taken preoperatively to diagnose osteomyelitis. The ankle-brachial index, toe-brachial index (TBI), and current perception threshold were checked. Lower extremity angiography was performed and if necessary, percutaneous transluminal angioplasty was conducted preoperatively. As a surgical treatment, meticulous debridement, bone curettage, and ALCS placement were employed in all cases. Between six and eight weeks after surgery, ALCS removal and autogenous iliac bone graft were performed. The treatment was considered successful if the wounds had healed completely within three months without signs of infection and no additional amputation within six months. RESULTS: The treatment success rate was 82.1% (n=32); 12.8% (n=5) required additional amputation and 5.1% (n=2) showed delayed wound healing. Bacterial growth was confirmed in 82.1% (n=32) with methicillin-resistant Staphylococcus aureus being the most commonly identified strain (23.1%, n=9). The lesions were divided anatomically into four groups; the largest number was the toes: (1) toes (41.0%, n=16), (2) metatarsals (35.9%, n=14), (3) midfoot (5.1%, n=2), and (4) hindfoot (17.9%, n=7). A significant difference in the Strauss wound score and TBI was observed between the treatment success group and failure group. CONCLUSION: The insertion of ALCSs can be a useful treatment option in diabetic foot infections with osteomyelitis. Low scores in the Strauss classification and low TBI are risk factors of treatment failure.


Subject(s)
Amputation, Surgical , Angiography , Angioplasty , Ankle Brachial Index , Classification , Curettage , Debridement , Diabetic Foot , Follow-Up Studies , Lower Extremity , Magnetic Resonance Imaging , Metatarsal Bones , Methicillin-Resistant Staphylococcus aureus , Osteomyelitis , Retrospective Studies , Risk Factors , Toes , Transplants , Treatment Failure , Wound Healing , Wounds and Injuries
20.
Article in English | WPRIM | ID: wpr-763578

ABSTRACT

BACKGROUND: Giant-cell tumor of bone (GCTB) is a locally aggressive primary benign tumor presenting as an expansile osteolytic lesion affecting the epiphysis of long bones. Denosumab halts the osteolysis by giant cells thereby downstaging the tumor, helping in performing less morbid procedures to remove the tumor. Our aim was to report the incidence of local recurrence (LR) in patients operated following neoadjuvant denosumab, to investigate factors associated with LR following extended curettage for GCTB, and to compare the postoperative functional and oncological outcome of patients operated with and without neoadjuvant denosumab. METHODS: A total of 123 patients with a mean age of 29.6 years undergoing extended curettage for GCTB were retrospectively divided into group 1 receiving neoadjuvant denosumab and group 2 operated without denosumab. The mean follow-up period was 35 months. The perioperative characteristics and outcome were compared between the two groups and the factors for LR of GCTB were analyzed. RESULTS: The incidence of LR among patients operated after neoadjuvant denosumab therapy was 42.8% and was significantly high compared to that in patients without denosumab (p < 0.001). On multivariate logistic regression analysis, use of denosumab as a neoadjuvant was the only factor independently associated with LR following surgery (p = 0.002). Patients treated with denosumab had a lower LR-free survival rate (log-rank, p = 0.018). CONCLUSIONS: Denosumab was independently associated with increased LR following surgery for GCTB. Denosumab has to be used cautiously in patients in whom the burden of downstaging the disease outweighs the possible chance of LR.


Subject(s)
Curettage , Denosumab , Epiphyses , Follow-Up Studies , Giant Cell Tumors , Giant Cells , Humans , Incidence , Logistic Models , Osteolysis , Recurrence , Retrospective Studies , Survival Rate
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