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An. bras. dermatol ; 96(5): 574-577, Sept.-Oct. 2021. graf
Article in English | LILACS | ID: biblio-1345148


Abstract Neutrophilic dermatoses encompass a wide spectrum of diseases characterized by a dense infiltration mainly composed of neutrophils. Neutrophilic dermatosis of the dorsal hands is currently considered a localized variant of Sweet syndrome. Cocaine abuse has been related to a wide range of mucocutaneous manifestations, including neutrophilic dermatoses such as pyoderma gangrenosum. The authors of this study present a patient with neutrophilic dermatosis of the dorsal hands, in which cocaine abuse was identified as a probable trigger.

Humans , Sweet Syndrome/diagnosis , Sweet Syndrome/chemically induced , Pyoderma Gangrenosum , Cocaine-Related Disorders/complications , Dermatitis , Neutrophils
J. coloproctol. (Rio J., Impr.) ; 41(3): 289-294, July-Sept. 2021. tab, ilus
Article in English | LILACS | ID: biblio-1346420


Purpose: Giant perianal condyloma (GPC) is a rare condition. The effective treatment is a multidisciplinary challenge; topical treatments are usually ineffective, and surgical resection has significant morbidity. Podophyllin at 25% in solid petrolatum (25%PSP) can be an effective treatment option for GPC. The aim of the present study was to assess its response and tolerability. Methods: This retrospective, single-center case series evaluated the clinical response of 14 patients with GPC treated with 25%PSP in a public hospital in Buenos Aires between December 2015 and December 2019. After obtaining a full history and performing a physical exam, the lesions were measured and photographed. Biopsies were performed to exclude malignancy, as well as exams to rule out pregnancy. Podophyllin at 25% in solid petrolatum was administered topically in cases of GPC and washed off by the patients at home after 4 hours. The patients underwent at least 4 weekly visits, which included interval history, photodocumentation of the lesions, and provider-applied 25%PSP. The response rate was assessed by comparingmeasurements and the overall decrease in volume of the GPC based on photos from the first and last sessions. Adverse outcomes were noted. Results: In total, 10 men, 3 women, and 1 transgender woman with GPC unresponsive to prior treatments and a mean age of 34.5 years were included. A total of 12 patients were immunosuppressed. All the perianal lesions were circumferential and measured between 8 cm and 20 cm. Overall, 7 patients had genital condyloma outside of the anus and perianus; the histology showed low-grade squamous intraepithelial lesions in all cases. While on treatment, 7 patients reported dermatitis, and 71% of the patients had 75% reduction in lesion size. Conclusions: Podophyllin at 25% in solid petrolatum is an effective, well-tolerated topical treatment option for GPC. (AU)

Humans , Male , Female , Adolescent , Adult , Middle Aged , Podophyllin/therapeutic use , Dermatitis/complications , Condylomata Acuminata/therapy
J. coloproctol. (Rio J., Impr.) ; 41(2): 145-151, June 2021. tab
Article in English | LILACS | ID: biblio-1286981


Objective: To develop green banana peel (Musa sapientum) powder for the treatment of peristomal dermatitis, and to evaluate its effectiveness and healing time. Methods: A clinical, analytical and longitudinal study. In total, 44 volunteers of both genders, aged>18 years, with intestinal ostomy, who presented peristomal dermatitis, participated in the research. The sample was divided into two groups: the study group used a powder containing 10% of green banana peel, and the control group used ostomy powder. The research was approved by the Ethics in Research Committees (Comitês de Ética em Pesquisa, CEP, in Portuguese) under opinion n° 2.381.904. Results: The healing time of the study group was shorter than that of the control group (p=0.022). To analyze the results, we used the two-sample t-test (mean days until healing for both study groups). Conclusion: The powder containing 10% of green banana peel was developed, and effective healing of the peristomal dermatitis was observed. Compared to the ostomy powder, it presented a shorter healing time. (AU)

Objetivo: Desenvolver o pó composto da casca da banana verde (Musa sapientum) para o tratamento de dermatite periestomal, e avaliar a eficácia e o tempo de cicatrização. Métodos: Estudo clínico, analítico e longitudinal. Participaram da pesquisa 44 voluntários, de ambos os gêneros, maiores de 18 anos, com estomias intestinais, e que apresentavam dermatite periestomal. A amostra foi dividida em dois grupos: o grupo de estudo usou umpó que continha 10% de casca de banana verde, e o grupo de controle usou pó para estomia. A pesquisa foi aprovada pelos Comitês de Ética em Pesquisa (CEP), sob o parecer n° 2.381.904. Resultados: O tempo de cicatrização do grupo de estudo foimenor do que o do grupo de controle (p=0.022). Para a análise dos resultados, empregou-se o teste t para duas amostras (média de dias de cicatrização de ambos os grupos). Conclusão: Desenvolveu-se o pó contendo 10% de casca de banana verde, e observouse cicatrização eficaz da dermatite periestomal. Em comparação com o pó para estomia, apresentou tempo menor até a cicatrização. (AU)

Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Musa , Dermatitis/therapy , Surgical Stomas/adverse effects , Phytotherapeutic Drugs
Infectio ; 25(1): 28-32, ene.-mar. 2021. tab, graf
Article in English | LILACS, COLNAL | ID: biblio-1154398


Summary The Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus with oncogenic properties, affects around ten to twenty million people worldwide. The most common disorders associated with HTLV-1 infection are T-cell leukemia/lymphoma (ALT) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Studies have reported other clinical manifestations in HTLV-1 seropositive patients, including inflammatory disorders, co-infections with opportunistic agents, and pulmonary diseases. Objective: Here, we aim to describe a cohort of juvenile patients with confirmed HTLV-1 infection that showed clinical manifestations other than neurological symptoms. Methodology and patients: Retrospective analysis of clinical data describing background and clinical findings of 12 juvenile patients with confirmed HTLV-1 infection, attended during January 2018 to February 2020 in a pediatric referral hospital in Cali, Colombia. Results: 11 out 12 patients were from Colombia´s Pacific coast, 10 suffered from significant nutritional deficiencies. Six exhibited dermatological findings, 3 compatible with infective dermatitis. None of the cases exhibited clinical or laboratory findings suggesting ALT or HAM/TPS. Eight patients had structural lung disease assessed by chest Computed Tomography (CT) scans; 4 of them tested positive for galactomannan antigen in bronchoalveolar fluid suggesting pulmonary aspergillosis, and 2 others exhibited a positive PCR testing for tuberculosis. Three patients were diagnosed with autoimmune disorders; 1 patient with Crohn´s Diseases, 1 case of autoimmune thrombocytopenic purpura, and a patient with Vogt-Koyanagi-Harada syndrome (non-granulomatous uveitis). Conclusions: There is a broad range of clinical manifestations in pediatric HTLV-1 patients, and the clinician should consider structural pulmonary disease, opportunistic co-infections and autoimmune disorders in the diagnostic algorithm.

Resumen El Virus Linfotrópico de células T humanas tipo 1 (HTLV-1), retrovirus con propiedades oncogénicas, afecta alrededor de 10-20 millones de personas mundialmente. Las manifestaciónes más comúnmente asociadas a HTLV-1 incluyen leucemia/linfoma de células T (ALT) y mielopatía asociada a HTLV-1/ paraparesia espástica tropical (HAM/TSP). Estudios han reportado otras manifestaciones clínicas en pacientes positivos para HTLV-1, incluyendo enfermedades inflamatorias, coinfecciones con gérmenes oportunistas y enfermedad pulmonar. Objetivo: es describir clínicamente una cohorte de pacientes pediátricos con infección por HTLV-1 confirmada que presentan manifestaciones clínicas diferentes a síntomas neurológicos. Metogolodía y pacientes: Análisis retrospectivo de historia clínica describiendo procedencia y hallazgos clínicos en 12 pacientes con infección por HTLV-1 confirmada, atendidos durante el periodo de Enero de 2018 a Febrero de 2020 en un hospital pediátrico de referencia en Cali, Colombia. Resultados: Once de 12 pacientes procedían de la costa Pacífica Colombiana, 10 con deficiencias nutricionales significativas. Seis mostraron compromiso dermatológico, 3 compatibles con dermatitis infectiva. Ningún paciente presentó hallazgos clínicos o paraclínicos sugestivos de ALT o HAM/TPS. Ocho pacientes presentaron enfermedad pulmonar estructural evidenciada por TAC de tórax; 4 de ellos con antígeno galactomanan positivo en lavado broncoalveolar, sugiriendo aspergilosis pulmonar, y otros 2 resultaron con PCR positiva para tuberculosis. Tres pacientes presentaron enfermedades autoinmunes concomitantes: uno con Enfermedad de Crohn, uno con Púrpura Trombocitopénica Autoinmune, y un paciente con Síndrome de Vogt-Koyanagi-Harada. Conclusiones: Existe un amplio rango de manifestaciones clínicas en pacientes pediátricos con HTLV-1, considerando enfermedad pulmonar estructural, coinfecciones oportunistas y enfermedades autoinmunes dentro del algoritmo diagnóstico.

Humans , Infant , Child, Preschool , Child , Adolescent , Viruses , Human T-lymphotropic virus 1 , Infections , Paraparesis, Tropical Spastic , Leukemia , Crohn Disease , Coasts , Concurrent Symptoms , Uveomeningoencephalitic Syndrome , Purpura, Thrombocytopenic, Idiopathic , Malnutrition , Dermatitis , Pulmonary Aspergillosis , Lung Diseases
Pesqui. vet. bras ; 41: e06978, 2021. ilus
Article in English | LILACS, VETINDEX | ID: biblio-1351279


The present article presents cases of conidiobolomycosis in adult goats with clinical signs characterized by serous nasal discharge, dyspnea, apathy, and weight loss. Two goats were necropsied. Necropsy displayed increased volume on the sagittal section of the head and an ulcerated surface containing a yellow friable mass with irregular and granular consistency in the nasal septum and in the ventral nasal turbinate. One goat also presented lesions on the ear's skin and the right pelvic limb. Microscopically, lesions were characterized by multifocal granulomas with a central necrotic area containing non-stained fungal hyphae images surrounded by a granulomatous infiltrate. Samples of the lesions examined by immunohistochemistry and polymerase chain reaction were positive for Conidiobolus lamprauges. This is the first report of conidiobolomycosis in goats, and the disease should be considered in the differential diagnoses for rhinitis and dermatitis in goats.(AU)

O presente artigo apresenta casos de conidiobolomicose em cabras adultas com sinais clínicos caracterizados por secreção nasal serosa, dispneia, apatia e perda de peso. Dois caprinos foram necropsiados. Na necropsia, em corte sagital da cabeça, foi observado aumento de volume e superfície ulcerada contendo massa amarela e friável com consistência irregular e granular no septo nasal e conchas nasais ventrais. Uma cabra apresentou também lesões na pele da orelha e no membro pélvico direito. Microscopicamente, as lesões foram caracterizadas por granulomas multifocais com área central de necrose, contendo imagens de hifas fúngicas não coradas, circundadas por infiltrado inflamatório granulomatoso. Amostras das lesões submetidas à imuno-histoquímica e reação em cadeia da polimerase foram positivas para Conidiobolus lamprauges. Este é o primeiro registro de conidiobolomicose em caprinos e deve ser considerado no diagnóstico diferencial de rinite e dermatite em caprinos.(AU)

Animals , Goats/microbiology , Immunohistochemistry , Weight Loss , Rhinitis , Conidiobolus/pathogenicity , Dermatitis , Nasal Septum , Polymerase Chain Reaction
Rev. enferm. UERJ ; 28: e51323, jan.-dez. 2020.
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1146473


Objetivo: identificar a incidência de Dermatite Associada à Incontinência (DAI) e os fatores de risco em pacientes de uma unidade de internação clínica. Método: estudo de coorte prospectivo com 197 pacientes de unidade de internação clínica. Utilizou-se estatística descritiva e analítica e calculou-se o Risco Relativo com intervalo de confiança de 95%, considerando-se significativos quando p bicaudal <0,05. Estudo aprovado pelo Comitê de Ética em Pesquisa da Instituição. Resultados: a incidência de DAI foi de 20,3% (40 pacientes). O risco relativo para DAI foi significativamente maior em idosos, em uso de alimentação enteral, fraldas, oxigenoterapia, antifúngico, corticoide, glicosídeo cardíaco, vasodilatador ou antidispéptico. Também foi maior nos pacientes com 15 ou mais dias de internação ou naqueles com doenças classificadas como Transtornos Mentais e Comportamentais ou como Causas Externas Traumáticas. Conclusão: foi alta a incidência de DAI na população pesquisada, estando associada a fatores de risco que envolvem, sobretudo, dependência de cuidado.

Objective: to ascertain the incidence of Incontinence-Associated Dermatitis (IAD) and related risk factors among inpatients in a clinical unit. Method: in this prospective cohort study of 197 patients in an inpatient unit, descriptive and analytical statistics were used, and Relative Risk was calculated with a 95% confidence interval; these were considered significant at two-tailed p < 0.05. The research protocol was approved by the ethics commission. Results: incidence of IAD was 20.3% (40 patients). The relative risk IAD was significantly higher in the elderly, when using enteral feeding, diapers, oxygen therapy, antifungal, corticosteroids, cardiac glycoside, vasodilator or anti-dyspeptic. It was also higher in those with 15 or more days' hospitalization or with diseases classified as Mental and Behavioral Disorders or from External Traumatic Causes. Conclusion: the incidence of AID was high in the study population, and associated with risk factors that involved, above all, dependence on care. Descriptors: Nursing; Dermatitis; Urinary Incontinence; Fecal Incontinence.

Objetivo: determinar la incidencia de dermatitis asociada a incontinencia (DAI) y factores de riesgo relacionados entre pacientes hospitalizados en una unidad clínica. Método: en este estudio de cohorte prospectivo de 197 pacientes en una unidad de internación, se utilizó estadística descriptiva y analítica y se calculó el Riesgo Relativo con un intervalo de confianza del 95%; estos se consideraron significativos en p <0,05 de dos colas. El protocolo de investigación fue aprobado por la comisión de ética. Resultados: la incidencia de DAI fue del 20,3% (40 pacientes). El riesgo relativo de DAI fue significativamente mayor en los ancianos, al utilizar alimentación enteral, pañales, oxigenoterapia, antifúngicos, corticosteroides, glucósidos cardíacos, vasodilatadores o antidispépticos. También fue mayor en aquellos con 15 o más días de hospitalización o con enfermedades clasificadas como trastornos mentales y del comportamiento o de causas traumáticas externas. Conclusión: la incidencia de DAI fue alta en la población de estudio, y se asoció a factores de riesgo que involucraron, sobre todo, dependencia del cuidado.

Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Urinary Incontinence , Dermatitis/epidemiology , Fecal Incontinence , Hospitalization , Inpatients , Nursing Care , Brazil/epidemiology , Prospective Studies , Risk Factors , Cohort Studies , Mental Disorders
Nursing (Säo Paulo) ; 23(270): 4873-4886, nov.2020.
Article in Portuguese | LILACS, BDENF | ID: biblio-1145473


Objetivo:descrever o gerenciamento da dermatite associada a incontinência fecal e urinária pelo profissional enfermeiro. Método:Trata-se de um estudo bibliográfico, tipo revisão integrativa. Realizou-se a busca por artigos; publicados no período de 2015 a 2019; nos idiomas português, inglês e espanhol; disponíveis na íntegra. Foram consultadas as seguintes plataformas de dados: BIREME, LILACS e SciELO. Os dados foram organizados e apresentados em figuras e tabelas.Resultado: Dos 501 estudos encontrados, 32 foram selecionados para a leitura na integra; contudo, após a leitura permaneceram apenas os que atendiam aos critérios descritos na metodologia, totalizando 22 estudos. Após a leitura dos estudos selecionados, os artigos foram categorizados em recortes temáticos, classificando o conhecimento produzido acerca do tema.Conclusão:De uma forma geral, todos os estudos apontaram para a importância de uma adequada inspeção da pele, constituindo-se como o "gold standard" que quer dizer "Padrão ouro" da prevenção e diagnóstico de DAI.(AU)

Objective: to describe the management of dermatitis associated with fecal and urinary incontinence by the nurse professional. Method: This is a bibliographic study, type integrative review. The search for articles was carried out; published in the period from 2015 to 2019; in Portuguese, English and Spanish; available in full. The following data platforms were consulted: BIREME, LILACS and SciELO. The data were organized and presented in figures and tables. Result: Of the 501 studies found, 32 were selected for full reading; however, after reading, only those who met the criteria described in the methodology remained, totaling 22 studies. After reading the selected studies, the articles were categorized into thematic clippings, classifying the knowledge produced on the topic. Conclusion: In general, all studies pointed out the importance of an adequate skin inspection, constituting itself as the "gold standard", which means "gold standard" for the prevention and diagnosis of AID.(AU)

Objetivo: describirel manejo de ladermatitisasociada a incontinencia fecal y urinaria por parte delprofesional de enfermería. Método: Se trata de unestudio bibliográfico, tipo revisión integradora. Se realizólabúsqueda de artículos; publicado enel período de 2015 a 2019; enportugués, inglés y español; disponibleensutotalidad. Se consultaronlassiguientes plataformas de datos:BIREME, LILACS y SciELO. Los datosfueron organizados y presentados en figuras y tablas. Resultado: de los 501 estudios encontrados, 32 fueronseleccionados para lectura completa; sin embargo, luego de lalectura, solo quedaronaquellos que cumplieron com Los criterios descritosenlametodología, totalizando 22estudios. Luego de lalectura de losestudiosseleccionados, los artículos fueron categorizados en recortes temáticos, clasificandoelconocimientoproducido sobre el tema. Conclusión: En general, todos losestudiosapuntan a laimportancia de una adecuadainspeccióncutánea, constituyéndose como el "estándar de oro", que significa "estándar de oro" para laprevención y diagnóstico de la SIDA.(AU)

Humans , Urinary Incontinence , Dermatitis , Nursing Care , Practice Patterns, Nurses'
Rev. argent. reumatolg. (En línea) ; 31(3): 36-39, set. 2020. ilus
Article in Spanish | LILACS, BINACIS | ID: biblio-1149674


La dermatitis granulomatosa intersticial asociada a artritis (DGIaA) es una entidad muy poco frecuente que cursa con manifestaciones cutáneas y articulares. Clínicamente y en su forma cutánea, se caracteriza por la formación de cordones o "bandas" en disposición lineal (patognomónicas de esta enfermedad) o arciforme o erupciones de tipo papular o en placas, asociándose poliartritis. Se presenta un caso de una DGIaA, prestando especial atención a su relevancia clínico-patologica y a su diagnóstico y posterior tratamiento, haciendo una revisión en la literatura descripta.

Interstitial granulomatous dermatitis with arthritis is an unusual condition that occurs with skin and joint manifestations. Its cutaneous form, it is characterized by the formation of cords or "bands" in a linear arrangement (pathognomonic of this disease) or arciform or eruptions of papular type or in plates, being associated polyarthritis. We present a case of a DGIaA, with special attention to its clinical-pathological relevance to estabish diagnosis and subsequent treatment, making a bibliographic review.

Humans , Female , Dermatitis , Arthritis , Skin , Skin Manifestations , Therapeutics
Pesqui. vet. bras ; 40(8): 579-588, Aug. 2020. tab, ilus
Article in English | LILACS, VETINDEX | ID: biblio-1135663


Skin diseases in pigs can negatively impact the production. They cause losses related to the death of the affected pigs, to the cost with the treatment, growth retardation and condemnations in the slaughterhouses. This study was developed to determine the frequency and describe the histopathological findings of skin diseases in pigs in different age groups through a retrospective study from 2006 to 2018. A total of 154 conclusive cases were analyzed, including skin restricted diseases (allergic dermatitis, exudative epidermitis, vesicular dermatitis, pityriasis rosea, swinepox, follicular cyst, papilloma and scrotal hemangioma) or skin lesions secondary to systemic diseases (erysipelas, porcine dermatitis and nephropathy syndrome (PDNS), bacterial septicemia and multiple hemorrhages without definite cause). The skin lesions were classified as bacterial (46.1%), viral (26.6%), allergic (12.3%), neoplastic (1.3%) and others (13.6%). Swine erysipelas was the most frequent diagnosis (47/154), followed by PDNS (23/154), allergic dermatitis (19/154) and exudative epidermitis (15/154). Vesicular dermatitis (9/154), pityriasis rosea (9/154), septicemia with cutaneous manifestations (9/154), swinepox (9/154) and multiple hemorrhages without definite cause (7/154) were also observed. Follicular cyst (3/154), hyperkeratosis without definite cause (2/154), papilloma (1/154), and scrotal hemangioma (1/154) were less frequently described. Of the conclusive diagnosis, age was reported in 138 cases, with the highest frequency of skin lesions observed at the inspection process during slaughter (56/138).(AU)

As doenças de pele em suínos podem impactar negativamente a produção. Estas causam perdas relacionadas à morte dos acometidos, a custo com tratamentos, atraso no crescimento e condenações nos frigoríficos. Este trabalho foi desenvolvido para determinar a frequência e descrever os achados histopatológicos das doenças de pele em suínos nas diferentes faixas etárias, através de um estudo retrospectivo no período de 2006 a 2018. Foram analisados 154 casos conclusivos incluindo as doenças restritas a pele (dermatites alérgicas, epidermite exsudativa, dermatite vesicular, pitiríase rósea, varíola suína, cisto folicular, papiloma e hemangioma escrotal) e as secundárias a doenças sistêmicas (erisipela, síndrome dermatite nefropatia suína (SDNS), septicemia bacteriana e hemorragias múltiplas de causa não determinada). Estas foram classificadas em bacterianas (46,1%), virais (26,6%), alérgicas (12,3%), neoplásicas (1,3%) e outras (13,6%). A erisipela suína foi a enfermidade mais diagnosticada (47/154), seguida por SDNS (23/154), dermatite alérgica (19/154) e epidermite exsudativa (15/154). Observamos ainda dermatite vesicular (9/154), pitiríase rósea (9/154), septicemia bacteriana com manifestações cutâneas (9/154), varíola suína (9/154) e hemorragias múltiplas de causa não determinada (7/154). Em menor número, cisto folicular (3/154), hiperqueratose sem causa definida (2/154), papiloma (1/154) e hemangioma escrotal (1/154). Dos casos conclusivos, a idade foi informada em 138 casos, sendo a maior frequência das lesões de pele observadas na linha de inspeção, durante o abate (56/138).(AU)

Animals , Skin Diseases, Viral/pathology , Skin Diseases, Viral/epidemiology , Skin Diseases, Bacterial/pathology , Skin Diseases, Bacterial/epidemiology , Sus scrofa/injuries , Dermatitis/etiology , Dermatitis/pathology , Dermatitis/epidemiology , Skin/injuries , Swine Diseases , Abattoirs
Pesqui. vet. bras ; 40(5): 340-345, May 2020. ilus
Article in English | LILACS, VETINDEX | ID: biblio-1135633


The epidemiological, clinical and pathological aspects of cutaneous pythiosis occurring in cattle from three farms in the Northeastern of Brazil are described. A biopsy of the lesions of one bovine from each farm was performed. In two cases, the affected cattle had contact with water accumulated in dams during the dry season in the semiarid region. Another case occurred in the coastal tropical region in cattle grazing around irrigation channels. Clinically, lesions were observed mainly on the skin of the thoracic and/or pelvic limbs, characterized by flat and irregular ulcerated areas or nodules of varying sizes, some with fistulous tracts penetrating deep into the subcutaneous tissue. In one case the regional lymph nodes were affected. Histologically, in all cases, pyogranulomatous dermatitis associated with negative hyphae images, in hematoxylin-eosin stained sections, were observed. In sections stained by Grocott methenamine silver, the hyphae measured 2-8μm and had irregular ramifications and rare septations. Immunohistochemistry technique demonstrated strong immunolabeling for Pythium insidiosum. Pythiosis should be included in the differential diagnosis of dermatopathies in cattle in the Northeastern of Brazil.(AU)

Descrevem-se os aspectos epidemiológicos, clínicos e patológicos da pitiose cutânea em bovinos de três propriedades do Nordeste do Brasil. Uma biópsia das lesões de um bovino de cada propriedade foi realizada. Em dois casos, os bovinos afetados tiveram acesso à água acumulada em açudes durante a estação seca da região semiárida. O outro bovino acometido estava a pastoreio próximo a canais de irrigação na região litorânea. Clinicamente, as lesões foram observadas principalmente na pele dos membros torácicos e/ou pélvicos e caracterizavam-se por áreas planas e irregulares de ulceração ou nódulos de tamanhos variados, alguns com trajetos fistulosos penetrando profundamente no tecido subcutâneo. Em um caso, os linfonodos regionais foram afetados. Histologicamente, em todos os casos, observou-se dermatite piogranulomatosa associada a imagens negativas de hifas, em secções corados por hematoxilina e eosina. Em seções coradas por metenamina de prata de Grocott, as hifas mediam 2-8μm e possuíam ramificações irregulares com raras septações. A imuno-histoquímica demonstrou forte imunomarcação para Pythium insidiosum. A pitiose deve ser incluída como diagnóstico diferencial de dermatopatias de bovinos no Nordeste do Brasil.(AU)

Animals , Cattle , Cattle Diseases/epidemiology , Dermatitis/veterinary , Pythiosis/diagnosis , Pythiosis/pathology , Pythiosis/epidemiology , Pythium
J. coloproctol. (Rio J., Impr.) ; 40(2): 120-128, Apr.-Jun. 2020. graf, ilus
Article in English | LILACS | ID: biblio-1134977


ABSTRACT Objectives To develop an application program for prevention and treatment of complications of intestinal peristomal skin. Method The framework of the application software development were: Phase 1 - "Design, identification of the needs for the application development": In this phase, the authors identified during their clinical practice that some professionals and caregivers find it difficult to provide care for at-risk ostomized patients or those with some kind of peristomal skin complication; Phase 2 - "Application prototype development": this phase included the integrative literature review in the main databases; Phase 3 - "Creating the application": this phase was intended to generate a decision tree algorithms, structure the database, and develop the software; Phase 4 - "Transition": performing the application functionality testing. Results The application "Dermatite Periestoma App" has 36 screens and 21 figures describing the procedures for prevention and treatment of complications of intestinal peristomal skin. It is freely available from the Play Store and has been registered with the Instituto Nacional da Propriedade Industrial Ministério do Desenvolvimento, indústria e Comércio Exterior (Brazilian Ministry of Development, Industry and Foreign Trade, National Institute of Industrial Property). Conclusion This study made it possible to describe the stages of planning and development of the mobile application "Dermatite Periestoma App". The steps taken indicate that the "Dermatite Periestoma App" has great potential for clinical practice in the evaluation of patients with stomal complications or at risk for developing peristomal skin complications, preventive measures, therapeutic approaches, and for nursing education through the use of technology.

RESUMO Objetivos Desenvolver um aplicativo para prevenção e tratamento de complicações da pele periestoma intestinal. Método As fases de desenvolvimento da estrutura do aplicativo foram: Fase 1 - "Concepção, identificação das necessidades do desenvolvimento do aplicativo": nessa fase os autores identificaram, durante sua prática clínica, que alguns profissionais e cuidadores têm dificuldade em prestar assistência aos ostomizados com risco ou que adquirirem algum tipo de complicação da pele periestoma; Fase 2 - "Elaboração do protótipo do aplicativo": essa fase contemplou a revisão integrativa da literatura nas principais bases de dados; Fase 3 - "Construção do aplicativo": essa fase consistiu na elaboração da árvore de decisão dos algoritmos, estruturação do banco de dados e desenvolvimento do software; Fase 4 - "Transição": foram realizados os testes de funcionalidade do aplicativo. Resultados O aplicativo "Dermatite Periestoma App" tem 36 telas e 21 figuras descrevendo os procedimentos para prevenção e tratamento das complicações da pele periestoma intestinal. O mesmo está disponível gratuitamente naPlay Store e foi registrado no Instituto Nacional da Propriedade Industrial Ministério do Desenvolvimento, indústria e Comércio Exterior. Conclusão Este estudo possibilitou descrever as etapas do planejamento e desenvolvimento do aplicativo móvel "Dermatite Periestoma App". As etapas percorridas indicam que o "Dermatite Periestoma App" tem grande utilidade potencial para a prática clínica na avaliação do ostomizado com complicação ou que apresenta risco para desenvolver complicações da pele periestoma, medidas preventivas, condutas terapêuticas, e para o ensino de Enfermagem por meio do uso de tecnologia.

Humans , Ostomy , Dermatitis/prevention & control , Mobile Applications , Inflammatory Bowel Diseases , Dermatitis/complications
Rev. argent. dermatol ; 101(1): 51-60, mar. 2020. graf
Article in Spanish | LILACS | ID: biblio-1125806


RESUMEN La dermatitis actínica crónica (DAC) - dermatitis por fotosensibilidad, reacción solar persistente o su variante extrema el reticuloide actínico- es una fotodermatosis crónica, propia del adulto más frecuente en el sexo masculino provocada por rayos ultravioletas (UVB), (UVA) y luz visible. El diagnóstico es clínico, caracterizado por placas eccematosas y liquenificadas pruriginosas en aéreas expuestas al sol. Se cree que el DAC se debe a la fotosensibilización secundaria de un antígeno endógeno de la piel.

ABSTRACT Chronic actinic dermatitis (ACD) - photosensitivity dermatitis, persistent solar reaction or its extreme variant actinic reticuloid - is a chronic photodermatosis, typical of the adult male caused by ultraviolet (UVB), (UVA) and visible light. The diagnosis suggested by clinical researchers, characterized by eczematous and lichenified pruritic plaques in areas exposed to the sun. It is believed that DAC is due to the secondary photosensitization of an endogenous skin antigen.

Humans , Male , Middle Aged , Photosensitivity Disorders/diagnosis , Photosensitivity Disorders/therapy , Dermatitis/physiopathology , Diagnosis, Differential
Pesqui. vet. bras ; 40(1): 1-6, Jan. 2020. ilus
Article in English | LILACS, VETINDEX | ID: biblio-1091656


The aim of this work was to describe the epidemiological, clinical and pathological aspects of two outbreaks of spontaneous poisoning caused by Froelichia humboldtiana in cattle in Pernambuco, northeastern Brazil and reproduce experimentally this poisoning in cattle. Spontaneous poisonings of primary photosensitization occurred in two farms at the municipalities of Cachoeirinha and São Caetano and affected twenty-two adult bovines and two suckling calves after the rainy season. All bovines have recovered 21 days after they were removed from the pasture. To reproduce experimental poisoning, three cows and a calf were maintained in a pasture with 1ha composed by F. humboldtiana during 14 days. Clinical signs and skin lesions were similar in both spontaneous and experimental poisoning and consisted of cutaneous itching and hyperemia of non-pigmented areas of skin that evolved into edema, exudative dermatitis and extensive areas of skin necrosis. Serum levels of aspartate aminotransferase (AST), gamma glutamyltransferase (GGT), total, direct and indirect bilirubin were normal in all cattle examined. Histologically, lesions consisted of epidermal necrosis, hyperkeratosis with large amounts of degenerate neutrophils and acanthosis. In the dermis, edema and inflammatory infiltrate composed of eosinophils, lymphocytes and plasma cells mainly around the blood vessels were observed. In the experimental group, clinical signs of photosensitization were observed after the third day of F. humboldtiana consumption. The suckling calf displayed mild clinical signs of photodermatitis on the 8th day of the experiment. It was estimated that the average consumption of F. humboldtiana necessary to initiate clinical signs in each adult bovine was 78kg.(AU)

Os objetivos deste trabalho foram descrever os aspectos epidemiológicos, clínicos e patológicos de dois surtos de intoxicação por Froelichia humboldtiana em bovinos em Pernambuco e reproduzir experimentalmente essa intoxicação em bovinos. Intoxicações espontâneas foram observadas após o início do período chuvoso nos municípios de Cachoerinha e São Caetano. Vinte e dois bovinos apresentaram sinais clínicos e lesões cutâneas compatíveis com fotossensibilização primária, dentre os quais, dois bezerros lactentes. Todos os bovinos se recuperaram totalmente cerca de 21 dias após serem retirados da pastagem. Para reproduzir experimentalmente a intoxicação, três vacas, uma delas com bezerro ao pé, foram mantidas em um piquete de 1ha composto por F. humboldtiana por 14 dias consecutivos. O quadro clínico e as lesões tegumentares, tanto nos bovinos intoxicados nos surtos espontâneos, quanto nos bovinos do experimento consistiram em prurido e hiperemia em áreas despigmentadas de pele, que evoluíam para edema, dermatite exsudativa e necrose de áreas extensas de pele. Em todos os bovinos examinados, os níveis séricos de aspartato aminotransferase (AST), gamaglutamiltransferase (GGT), bilirrubina total, direta e indireta estavam normais. Histologicamente, as lesões consistiram em necrose da epiderme, hiperqueratose com grande quantidade de neutrófilos degenerados e acantose. Na derme havia edema e infiltrado inflamatório composto por eosinófilos, linfócitos e plasmócitos principalmente ao redor dos vasos sanguíneos. Nos bovinos do experimento, sinais clínicos de fotossensibilização foram observados após o terceiro dia de consumo de F. humboldtiana. O bezerro lactente apresentou sinais clínicos leves de fotodermatite no 8º dia do experimento. Estimou-se que o consumo médio de matéria seca de F. humboldtiana necessário para iniciar os sinais clínicos em cada bovino adulto foi de 78kg.(AU)

Animals , Cattle , Plant Poisoning/veterinary , Dermatitis, Photoallergic/etiology , Cicer/poisoning , Cicer/toxicity , Dermatitis, Photoallergic/veterinary , Dermatitis/etiology , Dermatitis/veterinary
Dermatol. argent ; 26(1): 2-10, 2020. ilus, tab
Article in Spanish | LILACS | ID: biblio-1146328


El síndrome de Sézary (SS) es una rara y agresiva variante leucémica del linfoma cutáneo de células T, de pronóstico ominoso. Se caracteriza por presentar la tríada eritrodermia, linfadenopatías y linfocitos T neoplásicos circulantes. El diagnóstico está dado por la clínica, el estudio histopatológico, la citometría de flujo y el reordenamiento genético del receptor del linfocito T. En esta revisión se analizan la presentación clínica, la histopatología, el diagnóstico y el pronóstico de este síndrome. (AU)

Sézary syndrome (SS) is a rare and aggressive leukemic cutaneous T-cell lymphoma with poor prognosis. Is characterized by a triad of erythroderma, lymphadenopathy and circulating neoplastic T cells. Diagnosis is made by clinical features, histopathology, flow cytometry and T-cell receptor gene rearrangements. In this review we will analyze clinical presentation, histopathology, diagnosis and prognosis of SS. (AU)

Humans , Male , Female , Middle Aged , Skin Neoplasms/diagnosis , Sezary Syndrome/diagnosis , Prognosis , Mycosis Fungoides/diagnosis , Dermatitis/diagnosis , Diagnosis, Differential
Rev. chil. reumatol ; 36(1): 24-30, 2020. tab, ilus
Article in Spanish | LILACS | ID: biblio-1282370


l lupus eritematoso es una afección que se conoce desde antiguo, referida en especial al compromiso cutáneo, pero ha sido mejor definida desde principios del siglo XIX, constituyéndose como una enfermedad sistémica con una base autoinmune. Mecanismos patogénicos inmunogenéticos desempeñan un papel en la susceptibilidad a la enfermedad, sobre la que actuarían variaciones hormonales y factores ambientales. De esta interacción deriva la producción de múltiples anormalidades inmunológicas, cuya acción sobre los tejidos da origen a la expresión clínica de la enfermedad. La relación entre el compromiso cutáneo, en especial crónico discoide, y sistémico, ha sido un factor de polémica, importante de dilucidar por el significado terapéutico y de pronóstico para el enfermo. De esta revisión se puede concluir que las diferentes manifestaciones del lupus constituyen una misma enfermedad, pero probablemente factores etiopatogénicos genéticos, hormonales y ambientales marcan la diferencia.

Lupus erythematosus is a condition that has been known since ancient times, especially referring to skin involvement, but has been better defined since the beginning of the 19th century, constituting itself as a systemic disease with an autoimmune basis. Immunogenetic pathogenic mechanisms play a role in disease susceptibility, on which hormonal variations and environmental factors would act. From this interaction derives the production of multiple immunological abnormalities, whose action on the tissues gives rise to the clinical expression of the disease. The relationship between cutaneous involvement, especially chronic discoid, and systemic, has been a controversial factor, important to elucidate due to its therapeutic and prognostic significance for the patient. From this review it can be concluded that the different manifestations of lupus constitute the same disease, but genetics, hormonal and environmental etiopathogenic factors probably make the difference.

Humans , Lupus Erythematosus, Cutaneous/pathology , Lupus Erythematosus, Systemic , Lupus Erythematosus, Cutaneous/classification , Dermatitis/etiology
Med. interna (Caracas) ; 36(4): 174-181, 2020. ilus, tab
Article in Spanish | LILACS, LIVECS | ID: biblio-1150783


Paciente femenina que presentó durante sus dos embarazos eritema nodoso, úlceras nasales y artritis. Debido a la persistencia del eritema nodoso después del segundo parto, se practicó determinación de ANA y anti-DNA ­ IF, resultando este último positivo, por lo que se plantea el diagnóstico de lupus eritematoso y es referida al Centro Nacional de Enfermedades Reumáticas, (CNER) donde se le practicó biopsia de piel que resultó compatible con lepra: borderline o dimorfa (BB-BL) en estado reaccional tipo II (eritema nodoso leproso: ENL). Se discuten algunos de aspectos de la lepra haciendo especial énfasis en síntomas que presentó la paciente y la exacerbación de los mismos durante los embarazos, posiblemente en relación con algunos cambios inmunológicos adaptativos que son generados para mantener la tolerancia materno fetal(AU)

Female young patient with erythema nodosum, nasal ulcers and arthritis during her two pregnancies. Due to the persistence of the erythema nodosum after the second delivery, ANA and anti-DNA - IF determination were done, the latter being positive, and she was diagnosed with lupus erythematosus and was referred to the National Center for Rheumatic Diseases, where skin biopsy showed to be compatible with leprosy: borderline or dimorphic (BB-BL) in type II reactional state (leprous erythema nodosum: LEN). Some aspects of leprosy are discussed with special emphasis on symptoms that the patient presented and their exacerbation during pregnancies, possibly in relation to some adaptive immunological changes that was generated to maintain maternal fetal tolerance(AU)

Humans , Female , Adult , Arthritis/physiopathology , Dermatitis/physiopathology , Leprosy , Lupus Vulgaris , Biopsy , Rheumatic Diseases , Papillomavirus Infections
Ciênc. cuid. saúde ; 19: e50154, 20200000.
Article in Portuguese | LILACS, BDENF | ID: biblio-1120011


Introduction: incontinence-associated dermatitis (IAD) is an inflammation of the skin, related to contact with moisture, frequent in patients with urinary and/or anal incontinence, which is an important challenge in nursing care. Objective: to identify the punctual prevalence and characteristics of incontinence-associated dermatitis (IAD) in adult patients admitted to the medical clinic of a general hospital. Method: a descriptive, cross-sectional study, carried out with a non-probabilistic sample of incontinent patients. Data were collected on 2 days in March 2019, through interviews, physical examination and medical records, and analyzed using simple descriptive statistics. Results: a prevalence of dermatitis associated with incontinence of 56.2% was found in incontinent patients. Among the types of incontinence, it was identified that 12.5% of the patients had urinary incontinence, 18.8% anal incontinence and 68.7% double incontinence. IAD was more frequent in women, over 70 years of age, with double incontinence. Conclusion: the prevalence of IAD in the medical clinic of the hospital under study is considered high, with category 2 being more frequent, that is, with skin rupture associated with edema and erythema. The findings raise the need for further studies, discussions and implementation of continuing education in health, especially for nursing care related to the topic.

Introdução: a dermatite associada à incontinência (DAI) é uma inflamação da pele, relacionada ao contato com a umidade, frequente em pacientes com incontinência urinária e/ ou anal que constitui importante desafio no cuidado de enfermagem.Objetivo:identificar a prevalência pontual e as características da dermatite associada à incontinência (DAI) em pacientes adultos internados na clínica médica de um hospital geral. Método:estudo descritivo, de corte transversal,realizado com amostra não probabilística de pacientes incontinentes. Os dados foram coletados em 2 dias do mês de março de 2019, mediante entrevista, exame físico e consulta a prontuário,e analisados por meio de estatística descritiva simples. Resultados:constatou-se prevalência de dermatite associada à incontinência de 56,2% nos pacientes incontinentes.Entre os tipos de incontinência, identificou-se que 12,5%dos pacientes apresentavam incontinência urinária, 18,8% incontinência anal e 68,7% dupla incontinência. A DAI foi mais frequente em mulheres, acima de 70 anos de idade, com dupla incontinência. Conclusão: a prevalência de DAI na clínica médica do hospital em estudo é considerada elevada, sendo mais frequente a categoria 2, ou seja, com ruptura da pele associada a edema e eritema. Os achados suscitam a necessidade de maiores estudos, discussões e implementação de ações de educação permanente em saúde, sobretudo para o cuidado de enfermagem relacionado ao tema.

Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Urinary Incontinence , Dermatitis , Diaper Rash , Fecal Incontinence , Pathology , Aging , Clinical Medicine , Nursing , Empathy , Medical Chaperones , Hospitalization , Hospitals , Nursing, Team