Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 975
Filter
1.
Rev. cub. inf. cienc. salud ; 32(1): e1753, tab, fig
Article in Spanish | LILACS, CUMED | ID: biblio-1280194

ABSTRACT

El estudio tuvo como objetivo examinar la viabilidad de la aplication de herramientas que ilustren el uso de la colección y de la institución, por parte la comunidad usuaria de la Biblioteca Provincial "Martí", y contribuyan a una mejor toma de decisiones. La investigación se basó en una combinación de métodos cualitativos y cuantitativos; entre ellos, los matemáticos y estadísticos y las herramientas de visualización de la información. La muestra comprendió 1 422 usuarios, representativa del 25 por ciento del total de la población de la Biblioteca Provincial "Martí", de Villa Clara. A partir de la información que se generó en el sistema de control estadístico de la institución, se recolectaron, se procesaron y se analizaron indicadores relativos al índice de captación, los servicios por usuarios, el uso de la biblioteca, el índice de circulación de la colección, el índice de rotación de la colección y el co-uso de los documentos por temáticas. Los datos revelaron aspectos esenciales de la gestión de la institución objeto de estudio y la necesidad de acometer acciones con respecto a su política de adquisición y de difusión, a fin de revertir los aspectos con incidencia negativa. El trabajo concluye con el reconocimiento de que la aplicación de esta novedosa forma de tratar los datos es una alternativa para la presentación de información en el proceso de la toma de decisiones de cualquier institución similar(AU)


The purpose of the study was to examine the viability of the application of tools that illustrate the use of the collection and the institution, by the user community of the Martí Provincial Library, which contributes to better decision-making.The research was based on a combination of qualitative and quantitative methods, among them mathematical and statistical, and information visualization tools. The sample was composed of 1 422 users representing 25 percent of the total population of Martí Provincial Library in Villa Clara. Starting from the information generated by the statistical control system of the institution, indicators were collected, processed and analyzed which had to do with the following variables: recruitment rate, services per user, use of the library, collection circulation rate, collection turnover rate, and document co-use by subject. The data revealed essential aspects of management at the study institution, as well as the need to implement actions related to their acquisition and dissemination policy with a view to improving deficient areas. The paper recognizes that application of this novel way to treat data is an alternative for the presentation of information in the decision-making process at any similar institution(AU)


Subject(s)
Humans , Diffusion , Information , Indicators and Reagents , Libraries
2.
Rev. cub. inf. cienc. salud ; 31(4): e1667, oct.-dic. 2020. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1156345

ABSTRACT

El fenómeno denominado infodemia consiste en un flujo masivo de información que se produce durante las crisis sociales. La difusión y el consumo de información por diversos medios oficiales y no oficiales sobre la enfermedad del coronavirus (COVID-19) y los aspectos relacionados con los métodos de prevención, los síntomas de la enfermedad, las opciones terapéuticas, entre otros, han crecido de forma continua desde su reporte oficial a finales del año 2019.1) La información sin sustento científico o la información científica indebidamente utilizada y disponible en las redes sociales podría favorecer la promoción de medidas de seguridad ineficientes, opciones terapéuticas de eficacia desconocida, o ambos,2,3 por lo que resulta importante cuantificar ese tipo de información como una de las estrategias de afrontamiento4 y de aproximación a la almetría de las publicaciones científicas sobre COVID-19 en las redes sociales.5 En ese sentido, nuestro objetivo fue estimar la proporción de publicaciones con contenido verificado en artículos científicos que son compartidos en grupos de Facebook dedicados a la COVID-19 y que fueron creados entre los meses de enero y marzo del año 2020(AU)


Subject(s)
Humans , Coronavirus , Diffusion , Information , Social Networking
4.
Semina cienc. biol. saude ; 41(2, Supl.): 275-282, jun./dez. 2020. Tab
Article in Portuguese | LILACS | ID: biblio-1247464

ABSTRACT

Bactérias ácido láticas (BAL) produzem substâncias inibitórias de patógenos e deteriorantes de alimentos e isso tem despertado interesse sobre seu uso na preservação e na segurança sanitária desses produtos. Assim, o estudo foi realizado com o objetivo de avaliar a atividade inibitória de Streptococcus infantarius subsp. infantarius isoladas de queijo de coalho artesanal do Sertão da Paraíba frente a microrganismos indicadores. A avaliação do potencial antagônico foi realizada pela técnica de difusão em disco frente à estirpe reveladora Escherichia coli, isolada das mesmas amostras de queijos e frente ao patógeno de referência Escherichia coli ATCC 3539. Das 11 estirpes analisadas, 81,8% foram capazes de inibir o microrganismo indicador isolado dos mesmos queijos de coalho, enquanto 36,4% das bactérias láticas apresentaram inibição frente ao patógeno de referência. Conclui-se que as cepas Streptococcus infantarius subsp. infantarius isoladas de queijos de coalho do Sertão da Paraíba apresentam potencial antagônico e podem assegurar a qualidade microbiológica de alimentos fermentados, inclusive o queijo de coalho.(AU)


Lactic acid bacteria (BAL) produce pathogen inhibiting and food damaging substances and this has raised interest in their use in the preservation and health safety of these products. Thus, the study was carried out with the objective of evaluating the inhibitory activity of Streptococcus infantarius subsp. infantarius isolated from artisanal coalho cheese from Sertão da Paraíba against indicator microorganisms. The evaluation of the antagonistic potential was performed using the disk diffusion technique against the Escherichia coli revealing strain, isolated from the same cheese samples and against the reference pathogen Escherichia coli ATCC 3539. Of the 11 strains analyzed, 81.8% were able to inhibit the indicator microorganism isolated from the same coalho cheeses, while 36.4% of the lactic acid bacteria showed inhibition compared to the reference pathogen. It is concluded that the strains Streptococcus infantarius subsp. infantarius isolated from coalho cheeses from Sertão da Paraíba have antagonistic potential and can ensure the microbiological quality of fermented foods, including coalho cheese.(AU)


Subject(s)
Humans , Bacteria , Escherichia coli , In Vitro Techniques , Health , Diffusion , Lactobacillales , Food
5.
Rev. colomb. psiquiatr ; 49(2): 67-67, abr.-jun. 2020.
Article in Spanish | LILACS, COLNAL | ID: biblio-1115645

ABSTRACT

A raiz de la polemica originada por la difusión de un programa televisivo de opinion donde se denuncias maltratos a pacientes hospitalizados en instituciones nacionales de salud mental, la ACP emitió el siguiente comunicado que ponemos hoy como editorial de nuestra revista.


As a result of the controversy caused by the dissemination of an opinion television program where mistreatment of hospitalized patients in national mental health institutions is reported, the ACP issued the following statement that we put today as the editorial of our magazine.


Subject(s)
Humans , Male , Female , Television , Mental Health , Patients , Passive Cutaneous Anaphylaxis , Diffusion
6.
Rev. cub. inf. cienc. salud ; 31(2): e1487, abr.-jun. 2020. fig
Article in Portuguese | LILACS, CUMED | ID: biblio-1149840

ABSTRACT

A implementação de programas de compliance vem sendo cada vez mais difundida nos ambientes organizacionais, se destacando o compliance, com vistas a estar em conformidade com as questões jurídicas, aumentando a eficiência e minimizando os riscos. O objetivo do presente artigo situa-se na análise da difusão do compliance a partir da perspectiva na gestão da informação, bem como seu impacto nos aspectos jurídicos no Brasil, e com isso, refletir sobre as vantagens da adoção desses mecanismos como forma de ganho de competitividade. Dessa maneira, a presente pesquisa realizou um levantamento bibliográfico com o objetivo de realizar uma análise preliminar da gestão da informação enquanto ferramenta organizacional no contexto da saúde. Também foi analisado como o processo de compliance pode fazer uso da informação gerida com o intuito de diminuir o risco e aumentar a competitividade no contexto das organizações que possuem a saúde como área fim. Ressalta-se que se trata de uma pesquisa de caráter preliminar, que buscou chamar a atenção das organizações brasileiras do setor da saúde quanto ao uso da gestão da informação como ferramenta para o compliance. Sendo assim, concluiu-se preliminarmente que a prática do compliance, alinhada ao uso estratégico da informação, pode ser fundamental para a minimização de riscos e aumento da competitividade, especialmente pelo ganho de confiabilidade de ambiente, pautado na integridade e na segurança de investimentos(AU)


La implementación de programas de compliance (cumplimiento normativo) se ha generalizado cada vez más en entornos organizacionales, con miras a cumplir con los problemas legales, aumentar la eficiencia y minimizar los riesgos. El objetivo de este artículo es determinar la difusión del compliance desde la perspectiva de la gestión de la información, así como su impacto en los aspectos legales en Brasil, y con eso, reflexionar sobre las ventajas de adoptar estos mecanismos como una forma de obtener competitividade. En la presente investigación realizó una encuesta bibliográfica con el fin de realizar un análisis preliminar de la gestión de la información como herramienta organizativa en el contexto de la salud. También se analizó cómo el proceso de compliance puede hacer uso de la información administrada para reducir el riesgo y aumentar la competitividad en el contexto de las organizaciones que tienen la salud como área final. Esta es una investigación preliminar, que intenta atraer la atención de las organizaciones brasileñas del sector de la salud en cuanto al uso de la gestión de la información como herramienta para el compliance. Por lo tanto, se concluyó preliminarmente que la práctica del compliance, alineada con el uso estratégico de la información, puede ser fundamental para minimizar los riesgos y aumentar la competitividad, especialmente por la ganancia en la confiabilidad del entorno basada en la integridad y la seguridad de las inversiones(AU)


The implementation of compliance programs has been increasingly widespread in organizational environments, highlighting compliance, with a view to being in compliance with legal issues, increasing efficiency and minimizing risks. The objective of this article is to analyze the diffusion of compliance from the perspective of information management, as well as its impact on legal aspects in Brazil, and with that, to reflect on the advantages of adopting these mechanisms as a way of gaining competitiveness. In this way, the present research carried out a bibliographic survey with the objective of carrying out a preliminary analysis of information management as an organizational tool in the context of health. It was also analyzed how the compliance process can make use of managed information in order to reduce risk and increase competitiveness in the context of organizations that have health as an end area. It should be noted that this is a preliminary research, which sought to draw the attention of Brazilian organizations in the health sector regarding the use of information management as a tool for compliance. Therefore, it was preliminarily concluded that the practice of compliance, in line with the strategic use of information, can be fundamental to minimize risks and increase competitiveness, especially due to the gain in the reliability of the environment based on the integrity and security of investments(AU)


Subject(s)
Humans , Compliance , Diffusion , Information
7.
Rev. cub. inf. cienc. salud ; 31(2): e1575, abr.-jun. 2020. tab, fig
Article in Spanish | LILACS, CUMED | ID: biblio-1138847

ABSTRACT

Este trabajo pretendió abordar un problema muy actual de los sistemas de información relativo a la calidad de la información, principalmente en sus manifestaciones de desinformación y de información imprecisa, así como lo relativo a los vacíos de información. Se realizó una conceptualización de estas manifestaciones a partir de un análisis documental, tomando el criterio de autores contemporáneos de gran relevancia. Se consideraron algunos atributos de estas manifestaciones y el modelo de Karlova-Fisher relativo a su difusión social. Se valoraron las características de estas manifestaciones y el efecto que puede provocar en la toma de decisiones, así como en el manejo de la información en las instituciones. Se concluye con los retos que estas constituyen para la gestión de información institucional, entre los que se incluyen, por su importancia, algunos ajustes en la alfabetización informacional(AU)


The purpose of the study was to address a very current problem faced by information systems which has to do with information quality, mainly as manifested by misinformation and inaccurate information, and information gaps. Conceptualization of these manifestations was based on document analysis, taking into account the opinions of contemporary authors of great relevance. Some attributes of these manifestations were considered, as well as their social diffusion following the Karlova-Fisher model. An evaluation was conducted of the characteristics of the manifestations and their potential effect on decision making and information management at institutions. An analysis was also performed of the challenges posed by these manifestations to institutional information management, including, due to their importance, some adjustments to information literacy(AU)


Subject(s)
Humans , Communication , Information Management , Decision Making , Diffusion , Information Literacy
8.
Rev. cub. inf. cienc. salud ; 31(2): e1510, abr.-jun. 2020. tab, fig
Article in Spanish | LILACS, CUMED | ID: biblio-1138848

ABSTRACT

El presente trabajo tuvo como objetivo diseñar un plan de comunicación para el Sistema de Inteligencia Colaborativa del Grupo Empresarial BioCubaFarma correspondiente al período 2019-2020. Se utilizó una metodología basada en la propuesta de Paul Capriotti en torno a la planificación de la comunicación. Se emplearon el análisis documental, la encuesta y la observación no participante como técnicas, así como el cuestionario y la guía de observación como instrumentos de recopilación de información. Se incorporó el enfoque de la Norma española UNE 166006:2018 para la gestión de la vigilancia e inteligencia, que reconoce a la comunicación como uno de los componentes de este sistema de gestión, y se resaltó su importancia en la generación, conservación, diseminación y uso de la información en relación con sus públicos. A partir de un diagnóstico del proceso de vigilancia e inteligencia en el sector se definieron los públicos, los canales de comunicación, la temporalidad y el alcance del plan de comunicación. Se estableció un sistema de objetivos y se especificaron sus estrategias y tácticas. Se definieron las formas de evaluación y se analizó la comunicación desde su dinamismo, complejidad, intersubjetividad e interacción social, aspectos que contribuyen a la gestión del sistema de inteligencia colaborativa para la co-creación, difusión y promoción de productos y servicios informacionales de vigilancia e inteligencia como sustento de la toma de decisiones(AU)


The current paper had as objective to design a communication plan for the Collaborative Intelligence System of BioCubaFarma Enterprises Group, (period 2019-2020). A methodology based on Paul Capriotti's proposal related to the communication planning was used. Documental analysis, survey and non-participatory observation as techniques, and questionnaire and observation guide as instruments of data collection, were applied. The approach of the Spanish standard UNE 166006:2018 on surveillance and intelligence management was incorporated. The standard recognizes communication as one of the components of this system, highlighting its importance for generation, conservation, dissemination and use of information in relation to its audiences. A diagnosis of surveillance and intelligence processes in the sector was done in order to define audiences, communication channels, temporality and the scope of the Communication Plan. A target system was established, and its corresponding strategies with their tactics were specified and described. Based on the specific objectives and their strategies, the forms of assessment were defined. The communication was analyzed from its dynamism, complexity, inter-subjectivity and social interaction. These aspects contribute to the collaborative intelligence system management for co-creation, dissemination and promotion of information products and services related to surveillance and intelligence, which support decision-making processes(AU)


Subject(s)
Humans , Health Strategies , Communication , Diagnosis , Diffusion , Information
9.
Rev. colomb. anestesiol ; 48(1): 1-2, Jan.-Mar. 2020.
Article in English | LILACS, COLNAL | ID: biblio-1092913

ABSTRACT

The technological revolution of recent years has produced an absolute and irremediable alteration in the creation, production, diffusion, distribution, reproduction, use and consumption of contents of biomedical scientific journals.1 These changes include the way of transmitting knowledge and represent new and renewed evolutionary strategies of communication. Thirty years ago, we could predict that the electronic and technological revolution would dramatically change and gradually reduce the use of printed publications.2 We have reached that point, and regional and global scientific journals are no unaware of these changes. There has been a gradual shift toward the online content publication as a priority form of dissemination.


La revolución tecnológica de los últimos años ha producido una alteración absoluta e irremediable en la creación, producción, difusión, distribución, reproducción, uso y consumo de contenidos de las revistas científicas biomédicas.1 Estos cambios incluyen la forma de transmitir el conocimiento y representan nuevas y renovadas estrategias evolutivas de comunicación. Hace treinta años, podíamos predecir que la revolución electrónica y tecnológica cambiaría drásticamente y reduciría gradualmente el uso de las publicaciones impresas.2 Hemos llegado a ese punto, y las revistas científicas regionales y mundiales no son ajenas a estos cambios. Se ha producido un cambio gradual hacia la publicación de contenidos en línea como forma prioritaria de difusión.


Subject(s)
Humans , Publications , Knowledge , Diffusion , Electronics , Periodicals as Topic , Communication
10.
Semina cienc. biol. saude ; 41(1): 3-12, jan./jun.2020. Tab, Ilus
Article in Portuguese | LILACS | ID: biblio-1224198

ABSTRACT

The tendency to replace synthetic antimicrobials for natural ones in food industry and an increase in bacterial resistance to antibiotics resulted in a necessity to find new alternatives, and essential oils are emerging as promising substitutes for synthetic chemicals in food preservation. The objective of this work was to test the antimicrobial activity of oregano (OEO) and clove (CEO) essential oils over a range of bacteria, molds and yeast of importance as pathogens or food spoilage. The antimicrobial activity of oregano and clove essential oils were analyzed by disk diffusion method and broth microdilution test (MIC) of OEO and CEO were determined for each tested microorganism. OEO and CEO were evaluated in natura (IN) and after thermal processing (TP) at 120 o C for 5 min. Both OEO and CEO presented the same inhibition zones for IN and TP samples, for all tested microorganisms, indicating that these oils can be thermally processed maintaining their antimicrobial activity. For OEO and CEO, the more sensitive microorganisms were the fungi (Aspergillus niger, Penicillium citrinum and Candida albicans), followed by Staphylococcus aureus, Bacillus cereus and Methicillin - resistant Staphylococcus aureus (MRSA); the lowest antimicrobial activities were observed against Streptococcus mutans and Enterococcus faecalis. In general, OEO resulted in higher inhibition zones and lower MIC values for all tested microorganisms, suggesting that it was more effective as an antimicrobial agent than CEO (AU)


A preferência mundial para alimentos mais saudáveis e livres de aditivos químicos pelos consumidores, associada ao aumento da resistência bacteriana, resultaram na necessidade de medidas alternativas no setor de alimentos. Os óleos correspondem a antimicrobianos naturais e constituem uma classe emergente como substitutos dos produtos químicos sintéticos na conservação de alimentos. O objetivo deste trabalho foi avaliar a atividade antimicrobiana de óleos essenciais de orégano (OEO) e cravo (CEO ) frente a bactérias, fungos e leveduras de importância no setor de alimentos. OEO e CEO foram avaliados in natura (IN) e após processamento térmico (TP) a 120 o C por 5 minutos. Para avaliar a atividade antimicrobiana frente a cada microrganismo empregou-se o método de discodifusão e o teste de microdiluição em caldo (MIC). Tanto o OEO quanto o CEO apresentaram zonas de inibição semelhantes para amostras IN e TP, indicando que a atividade antimicrobiana desses óleos são resistentes a altas temperaturas. Os microrganismos mais sensíveis para ambos os óleos essenciais foram os fungos (Aspergillus niger, Penicillium citrinum e Candida albicans), seguidos por Staphylococcus aureus, Bacillus cereus e Staphylococcus aureus resistente à meticilina (MRSA). Já as cepas Streptococcus mutans e Enterococcus faecalis apresentaram uma maior resistência frente à atividade antimicrobiana dos óleos essenciais. Em geral, os maiores halos de inibição e menores valores de MIC foram obtidos quando empregado o OEO, sugerindo uma maior atividade microbiana do mesmo quando comparado ao CEO. (AU)


Subject(s)
Oils, Volatile , Food , Anti-Bacterial Agents , Yeasts , Diffusion , Food Preservation , Fungi
11.
Article in English | WPRIM | ID: wpr-810980

ABSTRACT

OBJECTIVE: We aimed to investigate the ability of readout-segmented echo-planar imaging (rs-EPI)-based diffusion tensor imaging (DTI) in assessing the microstructural change of extraocular muscles (EOMs) and optic nerves in patients with thyroid-associated orbitopathy (TAO) as well as in evaluating disease activity.MATERIALS AND METHODS: We enrolled 35 TAO patients and 22 healthy controls (HCs) who underwent pre-treatment rs-EPI-based DTI. Mean, axial, and radial diffusivity (MD, AD, and RD) and fractional anisotropy (FA) of the medial and lateral EOMs and optic nerve for each orbit were calculated and compared between TAO and HC groups and between active and inactive TAO groups. Factors such as age, sex, disease duration, mediation, and smoking history between groups were also compared. Logistic regression analysis was used to evaluate the predictive value of significant variables for disease activity.RESULTS: Disease duration was significantly shorter in active TAOs than in inactive ones (p < 0.001). TAO patients showed significantly lower FA and higher MD, AD, and RD than HCs for both medial and lateral EOMs (p < 0.001), but not the AD value of lateral EOMs (p = 0.619). Active patients had significantly higher FA, MD, and AD than inactive patients for medial EOMs (p < 0.005), whereas only FA differed significantly in the lateral EOMs (p = 0.018). The MD, AD, and RD of optic nerves were significantly lower in TAO patients than HCs (p < 0.05), except for FA (p = 0.129). Multivariate analysis showed that the MD of medial EOMs and disease duration were significant predictors for disease activity. The combination of these two parameters showed optimal diagnostic efficiency for disease activity (area under the curve, 0.855; sensitivity, 68.4%; specificity, 96.9%).CONCLUSION: rs-EPI-based DTI is promising in assessing microstructural changes of EOMs and optic nerves and can help to indicate the disease activity of TAO, especially through the MD of medial EOMs.


Subject(s)
Anisotropy , Diffusion Tensor Imaging , Diffusion , Echo-Planar Imaging , Humans , Logistic Models , Multivariate Analysis , Muscles , Negotiating , Optic Nerve , Orbit , Sensitivity and Specificity , Smoke , Smoking , Troleandomycin
12.
Article in English | WPRIM | ID: wpr-810964

ABSTRACT

BACKGROUND: Pulmonary hypertension (PH) is common in patients with idiopathic pulmonary fibrosis (IPF) and is associated with poor outcomes. This study was performed to determine the clinical efficacy of PH-specific therapeutic agents for IPF patients.METHODS: We performed a systematic review and meta-analysis using MEDLINE, EMBASE, and the Cochrane Central Register. We searched randomized controlled trials (RCTs) without language restriction until November 2018. The primary outcome was all-cause mortality to end of study.RESULTS: We analyzed 10 RCTs involving 2,124 patients, 1,274 of whom received PH-specific agents. In pooled estimates, the use of PH-specific agents was not significantly associated with reduced all-cause mortality to end of study compared with controls (hazard ratio, 0.99; 95% confidence interval [CI], 0.92, 1.06; P = 0.71; I² = 30%). When we performed subgroup analyses according to the type of PH-specific agent, sample size, age, forced vital capacity, diffusion lung capacity, and the extent of honeycombing, PH-specific agents also showed no significant association with a reduction in all-cause mortality. A small but significant improvement in quality of life, measured using the St. George Respiratory Questionnaire total score, was found in the PH-specific agent group (mean difference, −3.16 points; 95% CI, −5.34, −0.97; P = 0.005; I² = 0%). We found no significant changes from baseline in lung function, dyspnea, or exercise capacity. Serious adverse events were similar between the two groups.CONCLUSION: Although PH-specific agents provided small health-related quality-of-life benefits, our meta-analysis provides insufficient evidence to support their use in IPF patients.


Subject(s)
Diffusion , Dyspnea , Humans , Hypertension, Pulmonary , Idiopathic Pulmonary Fibrosis , Lung , Lung Volume Measurements , Mortality , Quality of Life , Sample Size , Treatment Outcome , Vasodilator Agents , Vital Capacity
14.
Article in English | WPRIM | ID: wpr-820819

ABSTRACT

OBJECTIVES: We investigated the characteristics of Streptococcus mutans in the national culture collection from Korea. Twenty-nine (dental plaque, n=27; endodontic infections, n=1; blood, n=1) isolates were included in this study.METHODS: Antimicrobial susceptibilities were tested using the disk diffusion test. Multilocus sequence typing (MLST), serotyping, and collagen-binding genes were used for polymerase chain reaction (PCR) and direct sequencing. A collagen-binding (to assess the adhesion properties) assay was performed. S. mutans demonstrated high susceptibility to antimicrobial agents. Differences in collagen-binding abilities of the cnm-positive and -negative groups were compared using the Mann-Whitney U test (P<0.05).RESULTS: MLST analyses revealed 25 sequence types (STs), 17 of which (ST213-ST229) contained new alleles. The strains were classified into four serotypes with the c type encompassing 79.3% of all strains, while the e, f, and k types representing 6.9% each. Analysis of the cnm and cbm genes, which encode the two surface adhesin components of S. mutans, revealed three cnm-positive strains, each displaying greater adhesion ability than those of the cnm-negative strains.CONCLUSIONS: This study highlights the presence of a wide variety of S. mutans genotypes in Korea. These findings may provide useful information regarding the pathogenesis of infectious diseases, such as dental caries.


Subject(s)
Alleles , Anti-Infective Agents , Bacteremia , Communicable Diseases , Dental Caries , Diffusion , Genotype , Inflammation , Korea , Molecular Epidemiology , Multilocus Sequence Typing , Polymerase Chain Reaction , Serogroup , Serotyping , Streptococcus mutans , Streptococcus
15.
Rev. argent. microbiol ; 51(4): 334-338, dic. 2019. graf
Article in Spanish | LILACS | ID: biblio-1057397

ABSTRACT

Resumen Los objetivos de este trabajo fueron estudiar la sensibilidad antibiótica de aislamientos de Corynebacterium pseudotuberculosis procedentes de pequeños rumiantes e investigar la presencia de integrones que contienen genes de resistencia. Se estudiaron 15 aislamientos de diferentes fuentes por los métodos de difusión y dilución. Por el método de difusión, amoxicilina-clavulánico, ampicilina, cefotaxima, cefoxitina, ciprofloxacina, cloranfenicol, eritromicina, estreptomicina, gentamicina, imipenem, kanamicina, norfloxacina, penicilina, rifampicina, tetraciclina, trimetroprima-sulfametoxazol y vancomicina fueron activos frente al 100% de los aislamientos, mientras que amicacina presentó resultados variables. En los aislamientos que desarrollaron frente a amicacina se investigó la presencia de integrones de clase 1. El resultado fue negativo, sugiriendo la ausencia del integrón. Utilizando el método de dilución, los antibióticos más activos correspondieron a los grupos de cefalosporinas, gluco-péptidos, macrólidos, quinolonas y tetraciclinas. Se demostró menor actividad de p-lactámicos y aminoglucósidos. No se registró variabilidad en los perfiles antibióticos en los aislamientos procedentes de diferentes fuentes.


Abstract The aims of this work were to study the antibiotic susceptibility in Corynebacterium pseudotuberculosis isolated from small ruminants and to determine the presence of integrons that contain resistance genes. Fifteen isolates of different sources were analysed using the diffusion and the dilution methods. When the diffusion method was performed, amoxicillin-clavulanic, ampicillin, cefotaxime, cefoxitin, ciprofloxacin, chloramphenicol, erythromycin, streptomycin, gentamicin, imipenem, kanamycin, norfloxacin, penicillin, rifampicin, tetracycline, trimethoprim-sulfamethoxazole and vancomycin were effective against the 100% of isolates, while amikacin showed variable results. The isolates that were able to grow with amikacin, were studied in relation to the presence of integron class 1. The result was negative, suggesting the absence of integron. Using dilution method, the antibiotics belonging to the cephalosporin, glycopeptide, macrolide, quinolone, and tetracycline groups were the most active ones for the C. pseudotuberculosis biovar ovis isolates. Less activity of p-lactam and aminoglycosides were observed. There was no observation of variability in the antibiotic patterns in the strains coming from different sources.


Subject(s)
Animals , Sheep/microbiology , Corynebacterium pseudotuberculosis/drug effects , Integrons/drug effects , Anti-Bacterial Agents/therapeutic use , In Vitro Techniques/methods , Ruminants/microbiology , Dilution/analysis , Diffusion/drug effects , Lymphadenitis/prevention & control
16.
Rev. colomb. anestesiol ; 47(4): 209-210, Oct-Dec. 2019.
Article in English | LILACS, COLNAL | ID: biblio-1042730

ABSTRACT

Editorial dissemination of research is the reflection of a scientific production and reward system which is not at its best at the present time in the world. Health sciences literature has been under the spotlight over the past few years and, as a result, its ability to provide valid, unbiased answers is widely challenged.1 There is growing evidence that suggests that a vast amount of biomedical scientific literature may contain significant bias2 and distortion,3 may not be reproducible,4 and that its methods may have been hijacked to serve vested interests, including financial gain.5 Regrettably, these occurrences have given rise to a growing amount of research waste.6 In this bed of thorns, each of us as academics, researchers, and users are partly to be blamed.


La difusión editorial de la investigación es el reflejo de un sistema de producción y recompensa científica que no pasa por su mejor momento en el mundo. La literatura en ciencias de la salud ha estado en el punto de mira durante los últimos años y, como resultado, su capacidad para proporcionar respuestas válidas e imparciales está ampliamente cuestionada.1 Cada vez hay más pruebas que sugieren que una gran cantidad de literatura científica biomédica puede contener importantes sesgos2 y distorsiones,3 puede no ser reproducible,4 y que sus métodos pueden haber sido secuestrados para servir a intereses creados, incluyendo el beneficio financiero.5 Lamentablemente, estos hechos han dado lugar a una cantidad cada vez mayor de residuos de investigación.6 En este lecho de espinas, cada uno de nosotros, como académicos, investigadores y usuarios, tenemos parte de culpa.


Subject(s)
Humans , Research , Unified Health System , Diffusion , Health Sciences , Literature
17.
Electron. j. biotechnol ; 42: 1-5, Nov. 2019. tab, graf
Article in English | LILACS | ID: biblio-1087340

ABSTRACT

Background: Fermentation strategies for bioethanol production that use flocculating Saccharomyces cerevisiae yeast need to account for the mechanism by which inhibitory compounds, generated in the hydrolysis of lignocellulosic materials, are tolerated and detoxified by a yeast floc. Results: Diffusion coefficients and first-order kinetic bioconversion rate coefficients were measured for three fermentation inhibitory compounds (furfural, hydroxymethylfurfural, and vanillin) in self-aggregated flocs of S. cerevisiae NRRL Y-265. Thièle-type moduli and internal effectiveness factors were obtained by simulating a simple steady-state spherical floc model. Conclusions: The obtained values for the Thiéle moduli and internal effectiveness factors showed that the bioconversion rate of the inhibitory compounds is the dominant phenomenon over mass transfer inside the flocs.


Subject(s)
Saccharomyces cerevisiae/metabolism , Biofuels , Yeasts , Benzaldehydes , Biodegradation, Environmental , Inactivation, Metabolic , Diffusion , Flocculation , Furaldehyde/analogs & derivatives
18.
Rev. colomb. cardiol ; 26(3): 113-114, May-Jun. 2019.
Article in Spanish | LILACS, COLNAL | ID: biblio-1058396

ABSTRACT

Desde hace ya varios anos ˜ la Revista Colombiana de Cardiología viene estrechando lazos de amistad con la Red de Editores de la Sociedad Europea de Cardiología, lo cual la ubica en una posición privilegiada en Latinoamérica y de cara a otras revistas científicas del país y de la región. Esta Red está comprometida con el fomento de la implementación de estándares editoriales de alta calidad entre las revistas con interés cardiovascular pertenecientes a las agremiaciones de la Sociedad Europea de Cardiología. Desempena˜ un papel relevante en la difusión de investigaciones científicas originales y promueve la educación y la armonización de la práctica clínica. En este sentido, la Red de Editores respalda las recomendaciones del Comité Internacional de Editores de Revistas Médicas y actualiza continuamente su documento sobre requisitos uniformes (anteriormente conocido como las directrices de Vancouver) para los manuscritos enviados a revistas biomédicas. Estos incluyen recomendaciones para la conducta, los informes, la edición y la publicación de trabajos académicos. En concordancia con lo anterior, la Revista Colombiana de Cardiología, ya publicó previamente Data Sharing: A New Editorial Initiative of the International Committee of Medical Journal Editors. Implications for the Editors' Network1 .


Subject(s)
Periodicals as Topic , Cardiology , Quality Management , Diffusion
19.
Article in English | WPRIM | ID: wpr-785650

ABSTRACT

BACKGROUND/AIMS: A risk prediction model for the development of hepatocellular carcinoma (HCC) from indeterminate nodules detected on computed tomography (CT) (Rad(CT) score) in patients with chronic hepatitis B (CHB)-related cirrhosis was proposed. We validated this model for indeterminate nodules on magnetic resonance imaging (MRI).METHODS: Between 2013 and 2016, Liver Imaging Reporting and Data System (LI-RADS) 2/3 nodules on MRI were detected in 99 patients with CHB. The Rad(CT) score was calculated.RESULTS: The median age of the 72 male and 27 female subjects was 58 years. HCC history and liver cirrhosis were found in 47 (47.5%) and 44 (44.4%) patients, respectively. The median Rad(CT) score was 112. The patients with HCC (n=41, 41.4%) showed significantly higher Rad(CT) scores than those without (median, 119 vs. 107; P=0.013); the Chinese university-HCC and risk estimation for HCC in CHB (REACH-B) scores were similar (both P>0.05). Arterial enhancement, T2 hyperintensity, and diffusion restriction on MRI were not significantly different in the univariate analysis (all P>0.05); only the Rad(CT) score significantly predicted HCC (hazard ratio [HR]=1.018; P=0.007). Multivariate analysis showed HCC history was the only independent HCC predictor (HR=2.374; P=0.012). When the subjects were stratified into three risk groups based on the Rad(CT) score (<60, 60–105, and >105), the cumulative HCC incidence was not significantly different among them (all P>0.05, log-rank test).CONCLUSIONS: HCC history, but not Rad(CT) score, predicted CHB-related HCC development from LI-RADS 2/3 nodules. New risk models optimized for MRI-defined indeterminate nodules are required.


Subject(s)
Asian Continental Ancestry Group , Carcinoma, Hepatocellular , Diffusion , Female , Fibrosis , Hepatitis B , Hepatitis B, Chronic , Hepatitis, Chronic , Humans , Incidence , Information Systems , Liver , Liver Cirrhosis , Liver Neoplasms , Magnetic Resonance Imaging , Male , Multivariate Analysis , Radiographic Image Interpretation, Computer-Assisted , Risk Assessment
20.
Article in English | WPRIM | ID: wpr-785422

ABSTRACT

OBJECTIVE: To investigate longitudinal changes in language function in left-hemispheric ischemic stroke patients as well as factors that influence language recovery until 1 year after stroke onset.METHODS: We analyzed data from 235 patients with first-ever left-hemispheric ischemic stroke. All patients completed the Korean version of the Frenchay Aphasia Screening Test (K-FAST) at 7 days (T1), 3 months (T2), 6 months (T3), and 1 year (T4) after stroke onset. Repeated measures analysis of variance (ANOVA) was used to investigate changes in language function between time points. Subgroup analysis was performed according to the K-FAST scores at T1. Stroke lesion volume was assessed using diffusion tensor images, and involvement of language-related brain regions was examined. Multiple regression analysis was used to analyze factors influencing improvement of K-FAST score.RESULTS: The K-FAST scores at T1, T2, T3, and T4 differed significantly (p < 0.05). In the subgroup analysis, only the severe group showed continuous significant improvement by 1 year. Factors that negatively influenced improvement of language function were the age at onset, initial National Institutes of Health Stroke Scale (NIHSS) score, and initial K-FAST score, whereas education level and stroke lesion volume positively affected recovery. Involvement of language-related brain regions did not significantly influence long-term language recovery after ischemic stroke.CONCLUSION: Recovery of language function varied according to the severity of the initial language deficit. The age at stroke onset, education level, initial severity of aphasia, initial NIHSS score, and total stroke lesion volume were found to be important factors for recovery of language function.


Subject(s)
Age of Onset , Aphasia , Brain , Diffusion , Education , Humans , Mass Screening , Prognosis , Rehabilitation , Stroke Volume , Stroke
SELECTION OF CITATIONS
SEARCH DETAIL