Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 1.749
Filter
1.
An. bras. dermatol ; 96(4): 429-435, July-Aug. 2021. tab, graf
Article in English | LILACS | ID: biblio-1285101

ABSTRACT

Abstract Background: Tacrolimus is used to prevent unaesthetic scars due to its action on fibroblast activity and collagen production modulation. Objectives: To evaluate the action pathways, from the histopathological point of view and in cytokine control, of tacrolimus ointment in the prevention of hypertrophic scars. Methods: Twenty-two rabbits were submitted to the excision of two 1-cm fragments in each ear, including the perichondrium. The right ear received 0.1% and 0.03% tacrolimus in ointment base twice a day in the upper wound and in the lower wound respectively. The left ear, used as the control, was treated with petrolatum. After 30 days, collagen fibers were evaluated using special staining, and immunohistochemistry analyses for smooth muscle actin, TGF-β and VEGF were performed. Results: The wounds treated with 0.1% tacrolimus showed weak labeling and a lower percentage of labeling for smooth muscle actin, a higher proportion of mucin absence, weak staining, fine and organized fibers for Gomori's Trichrome, strong staining and organized fibers for Verhoeff when compared to controls. The wounds treated with 0.03% tacrolimus showed weak labeling for smooth muscle actin, a higher proportion of mucin absence, strong staining for Verhoeff when compared to the controls. There was absence of TGF-β and low VEGF expression. Study limitations: The analysis was performed by a single pathologist. Second-harmonic imaging microscopy was performed in 2 sample areas of the scar. Conclusions: Both drug concentrations were effective in suppressing TGF-β and smooth muscle actin, reducing mucin, improving the quality of collagen fibers, and the density of elastic fibers, but only the higher concentration influenced elastic fiber organization.


Subject(s)
Animals , Cicatrix, Hypertrophic/pathology , Cicatrix, Hypertrophic/prevention & control , Cicatrix, Hypertrophic/drug therapy , Ointment Bases , Rabbits , Wound Healing , Tacrolimus , Ear/pathology
5.
Int. j. morphol ; 38(1): 147-152, Feb. 2020. tab, graf
Article in English | LILACS | ID: biblio-1056413

ABSTRACT

Dog ear is very important because of disease vulnerability. Therefore, gross anatomy and sectional anatomy on CT and MRI of the dog ear should be mastered by veterinarian. The purpose of this research was to present the digital atlases which high quality sectioned images and 3D models of detailed structures of dog ear could be displayed freely. In the sectioned images of a female beagle, ear structures were reconstructed by surface modeling to make 3D models. The sectioned images and 3D models were put into the browsing software and PDF file, respectively. Using the browsing software and the PDF file, gross and radiological anatomy of dog ear could be learned easily and accurately. The auditory tube of a dog was placed anterior to the tympanic cavity unlike human. The tensor tympani muscle of a dog was connected to the dorsal wall of the tympanic cavity with the malleus. No remarkable difference in the auditory ossicles, semicircular ducts, facial nerve, and endolymphatic duct was observed between dogs and humans. The software and the PDF file will be provided to other researchers freely to help contribute to veterinary research and education.


La oreja del perro es importante debido a la vulnerabilidad de enfermedad. Por lo tanto, el veterinario debe conocer plenamente la anatomía macroscópica y la anatomía seccional en la TC y la RM del oído del perro. El objetivo de esta investigación fue presentar los atlas digitales que podían mostrar imágenes seccionadas de alta calidad y modelos 3D de estructuras detalladas de orejas de perro. En las imágenes seccionadas de una hembra Beagle, las estructuras de las orejas se reconstruyeron mediante modelado de superficie con el objetivo de crear modelos 3D. Las imágenes seccionadas y los modelos 3D se colocaron en un software de navegación y un archivo PDF. El uso de software de navegación y el archivo PDF permiten un aprendizaje fácil y preciso de la anatomía macroscópica y radiológica de la oreja de perro. El músculo tensor del tímpano de un perro estaba conectado a la pared dorsal de la cavidad timpánica con el martillo. No se observaron diferencias notables en los huesecillos auditivos, los conductos semicirculares, el nervio facial y el conducto endolinfático entre perros y humanos. El software y el archivo PDF estarán disponibles libremente para los investigadores para ayudar en la investigación y educación veterinaria.


Subject(s)
Animals , Dogs , Ear/diagnostic imaging , Software , Anatomy, Cross-Sectional , Imaging, Three-Dimensional , Ear/anatomy & histology , Visible Human Projects , Ear Auricle/diagnostic imaging
6.
Codas ; 32(3): e20190040, 2020. tab, graf
Article in Portuguese | LILACS | ID: biblio-1133494

ABSTRACT

RESUMO Objetivo: investigar a variabilidade do Teste Dicótico de Sentenças por meio do teste e reteste em indivíduos normo-ouvintes. Método: foram avaliados 36 indivíduos na faixa etária de 19 a 44 anos, destros e com limiares auditivos dentro da normalidade. Realizou-se a avaliação audiológica básica e aplicação dos Testes Dicótico de Dígitos e Dicótico de Sentenças. Teste e reteste foram realizados em duas sessões, com intervalo de 30 a 40 dias, no mesmo turno. Resultados: na tarefa de integração: houve vantagem da orelha direita em ambas as sessões de avaliação; não houve diferença significante entre as medidas obtidas na orelha direita, nas duas sessões de avaliação, enquanto na orelha esquerda foi constatada diferença significante. Na análise das diferenças por orelhas entre teste e reteste, verificou-se que 64% dos indivíduos mantiveram o mesmo resultado na orelha direita; já na esquerda, apenas 36% dos indivíduos mantiveram o mesmo resultado em ambas as etapas e 44% apresentaram diferença de 10% entre as duas avaliações. Observou-se correlação positiva moderada tanto para a orelha direita (r = 0,420) quanto para a esquerda (r = 0,550) com tendência de melhora dos escores no reteste. Na tarefa de separação, houve pequena variabilidade apenas na orelha esquerda, também com melhora dos escores no reteste. Conclusão: foi verificada diferença significante entre as medidas obtidas no teste e reteste apenas na tarefa de integração na orelha esquerda, porém houve correlação positiva moderada entre as medidas obtidas nas duas sessões de avaliação, mostrando tendência de melhora dos escores na segunda sessão de avaliação.


ABSTRACT Purpose: to investigate the variability of the Dichotic Sentence Test through the test and retest in normal-hearing adults. Method: We evaluated thirty-six individuals aged 19 to 44 years old, right-handed and with normal hearing thresholds. We performed the basic audiological evaluation and then we applied the Dichotic Digit Test and Dichotic Sentence Test. The test and retest had two sessions, with an interval from 30 to 40 days, in the same shift. Results: In the integration task, there was an advantage of the right ear in both evaluation sessions. There was no significant difference between the measures obtained in the right ear in the two evaluation sessions, while in the left ear, we found a significant difference. In the analysis of the differences in ears between the test and the retest, we found that 64% of the individuals kept the same result in the right ear, while in the left one, only 36% of the individuals kept the same result in both stages and 44% showed a 10% difference between the two evaluations. We observed moderate positive correlation for both the right ear (r=0.420) and the left ear (r=0.550), with a tendency to improve retest scores. In the separation task, there was a small variability only in the left ear, also with improved retest scores. Conclusion: There was a significant difference between the measures obtained in the test and retest only in the integration task in the left ear, but there was a moderate positive correlation between the measures obtained in the two evaluation sessions, showing a tendency to improve scores in the second evaluation session.


Subject(s)
Humans , Adult , Young Adult , Dichotic Listening Tests , Language , Ear , Face , Hearing , Functional Laterality
7.
Acta otorrinolaringol. cir. cabeza cuello ; 48(1): 79-92, 20200000. graf, ilus, tab
Article in Spanish | LILACS | ID: biblio-1097456

ABSTRACT

La cirugía electiva en otología se ha visto afectada por la pandemia del COVID-19. No sabemos cuánto tiempo pasará hasta que veamos un descenso en el número de casos nuevos y podamos volver al ejercicio médico que conocíamos. Mientras tanto, debemos adaptarnos rápidamente a la nueva forma de funcionamiento de los servicios quirúrgicos en otología, siguiendo los protocolos que están surgiendo para la reactivación gradual y segura de esta clase de actividad. El objetivo de este artículo es realizar una revisión narrativa de la literatura sobre las nuevas recomendaciones para la reactivación de los servicios quirúrgicos otológicos durante esta pandemia, estableciendo pautas seguras en el manejo perioperatorio. Una de las metas más importantes es brindar una guía sobre la forma de comportarse dentro del ambiente de los quirófanos, sus cambios operacionales, el correcto uso de elementos de protección personal y dar a conocer métodos que busquen disminuir la exposición del equipo quirúrgico a la aerosolización, describiendo una técnica novedosa de vestido del microscopio de doble cubrimiento con extensión cefálica para el cirujano.


Otologic surgical procedures have been affected by the COVID-19 pandemic. Is not known how long it will be until we see a decrease in the number of new cases and when we will be able to return to our usual medical practice. Meanwhile, we must adapt quickly to a new surgical practice in the COVID era. This article discuses recommendations for reactivating otological surgical services during the pandemic, establishing safe guidelines for ear surgery and for postoperative patient follow-up. One of the most important goals is to provide recommendations on how to behave in the operating room, how to use personal protection elements and to present new methods that seek to reduce the exposure of the surgical team to aerosolization. Here we describe a novel technique using the already described double draping technique and adding an extension for the surgeon´s protection.


Subject(s)
Humans , Aerosols , Coronavirus Infections , Ear , Ear Diseases , Ambulatory Surgical Procedures
9.
An. bras. dermatol ; 94(2): 239-241, Mar.-Apr. 2019. graf
Article in English | LILACS | ID: biblio-1001133

ABSTRACT

Abstract Atypical fibroxanthoma is a rare superficial fibrohistiocytic tumor. Clinically, it presents itself as a painless, solitary, ulcerated, and slow-growing nodule found mainly on sun-exposed areas - especially of the head and neck - of elderly individuals. The diagnosis is based on histopathological and immunohistochemical features. Immunohistochemical staining plays a critical role for the exclusion of differential diagnoses. Since atypical fibroxanthoma has an indolent clinical course, surgical excision is adequate for treatment. We present a case of atypical fibroxanthoma on the ear of a patient.


Subject(s)
Humans , Male , Aged , Skin Neoplasms/diagnosis , Histiocytoma, Benign Fibrous/diagnosis , Skin Neoplasms/pathology , Immunohistochemistry , Histiocytoma, Benign Fibrous/pathology , Diagnosis, Differential , Ear
10.
Int. arch. otorhinolaryngol. (Impr.) ; 23(2): 137-141, 2019. ilus, tab, graf
Article in English | LILACS | ID: biblio-1010196

ABSTRACT

Introduction: Preoperative temporal bone imaging studies have been routinely performed prior to cochlear implantation. Radiologists need to report these examinations with special focus on the surgeon's expectations. Objectives: To provide a basic structured format, in the form of a checklist, for reporting preoperative computed tomography (CT) and to its clinical impact on operative findings. Methods: The preoperative temporal bone CT scans of 47 patients were analyzed and reported according to the proposed checklist. Intraoperative assessment of mastoidectomy, posterior tympanotomy and round window access was done by the surgeon in a blinded fashion and were correlated with the radiological findings to assess its significance. Results: The proposed radiological checklist was reliable in assessing operative difficulty during cochlear implantation. Contracted mastoid and lower tegmen position were associated with a greater difficulty of the cortical mastoidectomy. Presence of an air cell around the facial nerve (FN) was predictive of easier facial recess access exposure. Facial nerve location and posterior external auditory canal (EAC) wall inclination were predictive of difficult round window (RW) accessibility. Conclusion: Certain parameters on the preoperative temporal bone CT scan may be useful in predicting potential difficulties encountered during the key steps involved in cochlear implant surgery (AU)


Subject(s)
Infant , Child, Preschool , Child , Adult , Temporal Bone/diagnostic imaging , Preoperative Care , Cochlear Implantation , Round Window, Ear/diagnostic imaging , Tomography, X-Ray Computed , Prospective Studies , Cohort Studies , Ear/diagnostic imaging , Checklist
11.
Acta cir. bras ; 34(8): e201900804, 2019. tab, graf
Article in English | LILACS | ID: biblio-1038125

ABSTRACT

Abstract Purpose To develop a rabbit model of a short peripheral catheter (SPC) and to observe the effects of different flushing methods on blood vessels. Methods Thirty rabbits were randomly divided into three groups (A, B, and C), with ten rabbits per group. In group A, we used pulsed flush; in group B, we used uniform flush; and no treatment was used in group C. Results We observed that a uniform flush reduced blockage, phlebitis, and exudation compared to a pulsed flush by visual observation. The histopathological examination found that the morphological changes in group A were more severe than in group B and C related to loss of venous endothelial cells, inflammatory cell infiltration, edema, epidermal and chondrocyte degeneration, except for the thrombosis on group B that was more serious than in group A, especially in the distal side of puncture points. The distal region of groups A and B had more inflammatory cell infiltration than the proximal region. Thrombosis was more severe in the distal region than in the proximal region in group B. Conclusions The uniform flush produced less damage to the vascular endothelium and surrounding tissues and was superior to the pulsed flush. However, the uniform flush is prone to thrombosis.


Subject(s)
Animals , Male , Rabbits , Blood Vessels/pathology , Catheterization, Peripheral/methods , Phlebitis/etiology , Regional Blood Flow , Catheterization, Peripheral/adverse effects , Endothelium, Vascular/pathology , Endothelium, Vascular/ultrastructure , Random Allocation , Endothelial Cells , Disease Models, Animal , Ear/blood supply
12.
Article in Korean | WPRIM | ID: wpr-816602

ABSTRACT

BACKGROUND: Candida auris was first isolated from the ears of Japanese and Korean patients. However, the prevalence of yeast isolates from ear cultures and their antifungal susceptibility profiles in these nations remain unclear.METHODS: We assessed yeast isolates recovered from ear cultures from a university hospital in Korea over a 4-year period from January 2014 to December 2017. Species identification was performed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and/or sequence analysis. Antifungal minimal inhibitory concentrations (MICs) were determined using the broth microdilution method of the Clinical and Laboratory Standards Institute.RESULTS: Among 81 non-duplicate isolates from ear cultures, Cadida parapsilosis was the most frequently detected yeast species (34.6%), followed by C. auris (28.4%), Candida metapsilosis (9.9%), Candida orthopsilosis (8.6%), Candida albicans (7.4%), and others (11.1%). The MICs of the isolates were 0.125 to > 64 µg/mL, ≤0.03 to 4 µg/mL, 0.25 to 1 µg/mL, 0.125 to 1 µg/mL, and ≤0.03 to 2 µg/mL for fluconazole, voriconazole, amphotericin B, caspofungin, and micafungin, respectively. Of the 81 isolates, 44.4% (36/81) showed decreased susceptibility to fluconazole (MIC ≥4 µg/mL). Of the 23 C. auris isolates, 19 (82.6%) had a fluconazole MIC of ≥32 µg/mL. None of the isolates showed resistance to amphotericin B or echinocandins. Most of these patients suffered from chronic otitis media (84%).CONCLUSION: Candida parapsilosis complex and C. auris were the yeast species identified most frequently from ear cultures and they exhibited a high rate of fluconazole non-susceptibility, particularly C. auris.


Subject(s)
Amphotericin B , Asian Continental Ancestry Group , Candida , Candida albicans , Ear , Echinocandins , Fluconazole , Humans , Korea , Mass Spectrometry , Methods , Otitis Media , Prevalence , Sequence Analysis , Voriconazole , Yeasts
13.
Immune Network ; : 39-2019.
Article in English | WPRIM | ID: wpr-785822

ABSTRACT

Several gut commensals have been shown to modulate host immune response. Recently, many food derived microbes have also been reported to affect the immune system. However, a mechanism to identify immunostimulatory and immunoregulatory microbes is needed. Here, we successfully established an in vitro screening system and identified an immunoregulatory bacterium, Lactobacillus pentosus KF340 (LP340), present in various fermented foods. LP340 induced a regulatory phenotype in mice Ag presenting cells which, in turn, induced IL-10 and IFN-γ producing Type 1 regulatory T cells (Tr1 cells) from naïve CD4⁺ T cells. Naïve CD4⁺ T cells co-cultured with LP340 treated dendritic cells highly expressed cytokine receptor IL-27R and were CD49b and lymphocyte-activation gene 3 double positive. Oral administration of LP340 in mice with atopic dermatitis reduced cellular infiltration in affected ear lobes and serum IgE levels, thus, ameliorating the disease symptoms. This suggests a systemic immunoregulatory effect of LP340. These findings demonstrate that LP340, a bacterium derived from food, prevents systemic inflammation through the induction of IL-10 producing Tr1 cells.


Subject(s)
Administration, Oral , Animals , Dendritic Cells , Dermatitis, Atopic , Ear , Immune System , Immunoglobulin E , In Vitro Techniques , Inflammation , Interleukin-10 , Lactobacillus , Mass Screening , Mice , Phenotype , Receptors, Cytokine , T-Lymphocytes , T-Lymphocytes, Regulatory
14.
Article in English | WPRIM | ID: wpr-785451

ABSTRACT

BACKGROUND: Keloids are benign fibro-proliferative lesion, related to excessive inflammatory reactions in certain anatomical areas, including the auricles. Their specific etiology remains unclear; nonetheless they exhibit tumor-like characteristics of significant recurrence and cause emotional distress, even with various treatment strategies. We applied intermittent magnetic pressure therapy on ear keloids in combination with surgical excision, and present its effectiveness herein.METHODS: Ear keloid patients were treated with surgical excision followed by magnetic pressure therapy. The keloid tissues underwent excision and keloid marginal flaps were utilized for wound closure. Intermittent magnetic pressure therapy was applied 2 weeks after the surgical procedure. The pressure therapy consisted of a 3-hour application and 2-hour resting protocol (9 hr/day), and lasted for 6 months. The results were analyzed 6 months after the therapeutic procedures, using the scar assessment scale.RESULTS: Twenty-two ear keloids from 20 patients were finally reviewed. Among the keloids that completed the therapeutic course, 20 ear keloids out of 22 in total (90.9%) were successfully eradicated. Two patients (2 keloids) exhibited slight under-correction. Postoperative complications such as wound dehiscence or surgical site infection were not noted. The scar assessment scale demonstrated a significant improvement in each index. The intermittent pressure therapy led to patient compliance, and avoided pressure-related pain and discomfort.CONCLUSION: Excision followed by intermittent pressure application using a magnet successfully reduced the burden of fibro-proliferative keloids, and had good patient compliance. The role of intermittent pressure application and resting should be studied with regard to keloid tissue remodeling.


Subject(s)
Cicatrix , Ear , Humans , Keloid , Patient Compliance , Postoperative Complications , Recurrence , Surgical Wound Infection , Treatment Outcome , Wounds and Injuries
15.
Article in English | WPRIM | ID: wpr-785442

ABSTRACT

Due to the variety in the shape of dysmorphic cartilage, tragus reconstruction is one of the most challenging goals in otoplasty. The authors describe a method to reconstruct a prominent tragus in a simple way suitable for accounting for the size, shape, and location of the remaining ear. We present a case of tragus deformity in an 11-year-old female patient after a previous excision of pretragal skin tags. There was a small remnant of the deeply located dystopic cartilage in a horizontal orientation. The dystopic cartilage was used to reconstruct the tragus using a chondrocutaneous transposition flap. Only a small portion of the pre-existing cartilage was used to create a chondrocutaneous transposition flap that supplemented the portion of cartilage during tragus reconstruction. The result was a new tragus that showed acceptable improvement in shape, location, and projection. Patients with a small portion of pre-existing cartilage near the tragal wall may benefit from the use of this method for tragus reconstruction.


Subject(s)
Cartilage , Child , Congenital Abnormalities , Ear , Ear, External , Female , Humans , Methods , Skin , Surgical Flaps
16.
Article in English | WPRIM | ID: wpr-785306

ABSTRACT

Cornelia de Lange syndrome (CdLS) is a rare multisystemic disorder that is characterized by mental retardation, prenatal and postnatal growth retardation, limb anomalies, and distinctive facial features, which include arched eyebrows that often meet in the middle (synophrys), long eyelashes, low-set ears, small and widely spaced teeth, and a small and upturned nose. Ophthalmic manifestations include long eyelashes, nasolacrimal duct obstruction, myopia, ptosis, and strabismus. There has been no report of surgical treatment for esotropia and unilateral ptosis in patients with CdLS in Korea. I report a patient with CdLS who underwent surgical treatment for esotropia and unilateral ptosis with a good surgical outcome.


Subject(s)
De Lange Syndrome , Ear , Esotropia , Extremities , Eyebrows , Eyelashes , Humans , Intellectual Disability , Korea , Myopia , Nasolacrimal Duct , Nose , Strabismus , Tooth
17.
Article in English | WPRIM | ID: wpr-785300

ABSTRACT

BACKGROUND: The aim of this study was to evaluate the awareness of occupational hazards and personal protective equipment use among dental hygienists (DHs).METHODS: A total of 271 self-administered questionnaires were obtained from 280 DHs working at dental hospitals or clinics in Daegu and Gyeongsangbuk-do, Korea.RESULTS: The occupational hazards included work involving dust (94.1%), volatile substances (86.0%), noise (97.0%), and light-curing units (96.7%). The proportion of dental hygiene tasks that participants perceived as harmful were 42.4%, 51.7%, 9.2%, and 31.4% in the same order as above. The proportion of participants who used dust-proof masks during work involving dust was 1.1%. Those who wore gas-proof masks and gloves for work using volatile substances were 0.7% and 31.2%, respectively. Participants who used goggles for work involving light-curing units were 31.0%. None of the participants used ear plugs for work involving noise. A total of 22.9% of the participants recognized the Material Safety Data Sheet, while 79.7% had never been educated about harmful work environments.CONCLUSION: When compared to exposure status and perception of occupational hazards, the level of protective equipment use was very low. Extra measures to increase DHs’ use of personal protective equipment are necessary.


Subject(s)
Dental Hygienists , Dust , Ear , Eye Protective Devices , Humans , Korea , Masks , Material Safety Data Sheets , Noise , Occupations , Oral Hygiene , Personal Protective Equipment
18.
Article in Chinese | WPRIM | ID: wpr-774207

ABSTRACT

The extraction of pulse rate variability(PRV) in daily life is often affected by exercise and blood perfusion. Therefore, this paper proposes a method of detecting pulse signal and extracting PRV in post-ear, which could improve the accuracy and stability of PRV in daily life. First, the post-ear pulse signal detection system suitable for daily use was developed, which can transmit data to an Android phone by Bluetooth for daily PRV extraction. Then, according to the state of daily life, nine experiments were designed under the situation of static, motion, chewing, and talking states, respectively. Based on the results of these experiments, synchronous data acquisition of the single-lead electrocardiogram (ECG) signal and the pulse signal collected by the commercial pulse sensor on the finger were compared with the post-auricular pulse signal. According to the results of signal wave, amplitude and frequency-amplitude characteristic, the post-ear pulse signal was significantly steady and had more information than finger pulse signal in the traditional way. The PRV extracted from post-ear pulse signal has high accuracy, and the accuracy of the nine experiments is higher than 98.000%. The method of PRV extraction from post-ear has the characteristics of high accuracy, good stability and easy use in daily life, which can provide new ideas and ways for accurate extraction of PRV under unsupervised conditions.


Subject(s)
Ear , Electrocardiography, Ambulatory , Fingers , Heart Rate , Humans , Monitoring, Ambulatory , Motion , Pulse
19.
Article in English | WPRIM | ID: wpr-777123

ABSTRACT

OBJECTIVE@#To identify the effectiveness of auricular acupressure (AA) in patients with acute postoperative pain after surgery by systematic review.@*METHODS@#A search of randomized controlled trials was conducted in 5 English medical electronic databases and 4 Chinese databases. Two reviewers independently retrieved related studies, assessed the methodological quality, and extracted data with a standardized data form. Meta-analyses were performed using all time-points meta-analysis.@*RESULTS@#A total of 26 studies with 1,682 participants were included. Results showed that compared with conventional therapy, AA significantly improved the total effective rate [risk ratio=1.25, 95% confidence interval (CI), 1.13 to 1.37, Plt;0.0001; heterogeneity: Plt;0.0001, I=85%]. In the subgroup analysis, the results changed in different follow-up time and surgery categories. The pain relief in the AA group might be the most significant at 72 h after surgery (mean difference=-0.85, 95% CI,-1.20 to-0.50, Plt;0.0001) and in abdominal surgery (mean difference=-1.15, 95% CI,-1.41 to-0.90, Plt;0.0001). Sensitivity analysis demonstrated that the results of this meta-analysis were stable. No serious adverse effects were recorded.@*CONCLUSION@#It was recommended to provide AA to patients with acute postoperative pain. However, a more accurate estimate of the effect requires further rigorously designed large-scale and high-quality RCTs for improving acute postoperative pain after surgery.


Subject(s)
Acupressure , Methods , Acute Disease , Ear , Humans , Pain, Postoperative , Therapeutics , Publication Bias
20.
Article in Korean | WPRIM | ID: wpr-787505

ABSTRACT

BACKGROUND: Sarcopenia has become a major concern owing to its association with a high risk of fall or fracture and metabolic impairments. There is insufficient evidence to support the role of dietary protein intake in reducing the prevalence of sarcopenia. This study was conducted to investigate the variation in low skeletal muscle index (SMI) with the dietary levels of protein intake.METHODS: This study analyzed data of 3,482 male and 4,838 female aged 50 years or older from the Korean National Health and Nutrition Examination Survey (KNHNES) database (2008–2011). Low SMI was indicated by a value <0.789 in male and <0.512 in female. Multiple logistic regression was performed to analyze the association of SMI with protein intake, whereby it was tested whether the dietary intake of proteins met the estimated average requirement (EAR) or the reference nutrient intake (RNI) as stated in the dietary reference intake (DRI) for Koreans, 2015.RESULTS: Irrespective of sex, the prevalence of low SMI was significantly high when the protein intake did not meet the EAR or RNI. Following adjustment for covariates, the odds ratio (OR) for low SMI in subjects with unmet EARs was 1.63 (1.28–2.09) in male and 1.35 (1.10–1.66) in female. The OR for low SMI in subjects with unmet RNI was 1.74 (1.38–2.18) in male and 1.39 (1.14–1.69) in female.CONCLUSION: The prevalence of low SMI was significantly higher when the protein intake did not meet the EAR or RNI as stated in the DRI for Koreans.


Subject(s)
Dietary Proteins , Ear , Female , Humans , Logistic Models , Male , Muscle, Skeletal , Nutrition Surveys , Odds Ratio , Prevalence , Protein Deficiency , Recommended Dietary Allowances , Sarcopenia
SELECTION OF CITATIONS
SEARCH DETAIL