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2.
Rev. argent. cir ; 113(1): 117-120, abr. 2021. graf
Article in Spanish | LILACS, BINACIS | ID: biblio-1288181

ABSTRACT

RESUMEN La resección gástrica atípica ha demostrado ser beneficiosa para tumores submucosos. La técnica pre senta mayor riesgo cuando estos se desarrollan próximos a la unión esófago-gástrica (UEG). Para esta limitación se propuso la resección intragástrica mediante una técnica mixta combinando laparoscopia y endoscopia. En nuestro medio no existen publicaciones al respecto. Se trata de una mujer de 42 años, con lesión subepitelial-subcardial de 2 cm, evaluada mediante videoendoscopia alta (VEDA), compa tible con tumor del estroma gastrointestinal (GIST) evaluado mediante ecoendoscopia. La lesión fue resecada mediante abordaje combinado laparoendoscópico. Bajo visión laparoscópica se introdujeron en cavidad abdominal trocares con balón, y bajo visión endoscópica intragástrica se introdujeron estos en el estómago y se fijó la pared gástrica a la pared abdominal insuflando dichos balones. Posterior mente se realizó la resección de la lesión con sutura mecánica. El abordaje combinado es seguro y eficaz, simple en manos entrenadas, pero constituye una opción reproducible en casos seleccionados.


ABSTRACT Atypical gastric resection has proved to be beneficial to treat submucosal tumors. The technique is more difficult when these tumors develop next to the gastroesophageal junction (GEJ). Intragastric resection combining endoscopic and laparoscopic approach was proposed to solve this limitation. There are no publications about this technique in our environment. A 42-year-old female patients with a 2-mm subepithelial tumor below the cardia evaluated by upper gastrointestinal (UGI) videoendoscopy and endoscopic ultrasound suggestive of a gastrointestinal stroma tumor (GIST) underwent resection using the combined laparo-endoscopic approach. Under laparoscopic guidance, balloon-tipped trocars were introduced in the abdominal cavity and then into the stomach using endoscopic view. The balloons were inflated to fix the gastirc wall to the abdominal wall. The lesion was resected using mechanical stapler. The combined approach is safe and efficient, and simple to perform for trained professionals, constituting a reproducible option in selected cases.


Subject(s)
Laparoscopy , Esophagogastric Junction , Neoplasms , Patients , Stomach , Surgical Instruments , Vision, Ocular , Women , Wounds and Injuries , Cardia , Endosonography , Mechanics , Abdominal Cavity , Endoscopy , Environment , Hand , Methods
3.
Rev. colomb. gastroenterol ; 35(4): 506-518, dic. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1156332

ABSTRACT

Resumen La endosonografía es un método diagnóstico que viene revolucionando el abordaje de los pacientes con tumores del tracto gastrointestinal y de otros órganos y estructuras extradigestivas. En la actualidad, se viene posicionando como un método de elección en la evaluación de lesiones subepiteliales gastrointestinales y en la estadificación de muchos tumores gastrointestinales como de esófago, estómago, recto y páncreas. Por lo anterior pretendemos hacer una revisión de tema mostrando la evidencia de la endosonografía en indicaciones clásicas y aplicaciones actuales en tumores gastrointestinales.


Abstract Endosonography is a diagnostic method that has revolutionized the way to approach patients with tumors in the gastrointestinal tract and other extra-digestive organs and structures. Currently, it is a method of choice to assess subepithelial lesions of the gastrointestinal tract and to classify gastrointestinal tumors in the esophagus, stomach, rectum, and pancreas. Therefore, this literature review presents evidence on the classical indications of endosonography, as well as current applications to approach gastrointestinal tumors.


Subject(s)
Humans , Endosonography , Gastrointestinal Tract , Neoplasms , Pancreas , Rectum , Stomach , Esophagus , Methods
4.
Rev. colomb. gastroenterol ; 35(4): 527-532, dic. 2020. graf
Article in Spanish | LILACS | ID: biblio-1156335

ABSTRACT

Resumen El tratamiento actual para la obstrucción biliar maligna es la derivación biliar no quirúrgica con propósito paliativo. La cirugía tiene indicaciones específicas en pacientes con patología maligna con propósito curativo. Sin embargo, la obstrucción duodenal y del conducto biliar intra o extrahepático no dilatado hace que esta cirugía y el procedimiento endoscópico guiado por ultrasonografía endoscópica (USE) sean difíciles de realizar. Presentamos nuestra experiencia con el primer caso en Colombia, un país latinoamericano del tercer mundo. Consistió en una colecistogastrostomía guiada por USE, a partir de la utilización de una endoprótesis luminal (Lumen-apposing metal stents, LAMS) (HOT AXIOS stent, Xlumena Inc.; Mountain View, CA, Estados Unidos) de 15 mm × 10 mm, en un paciente masculino con cáncer pancreático inoperable e invasión duodenal con conducto colédoco dilatado. La colecistogastrostomía guiada por USE podría ser considerada como una opción de más importancia para la descompresión biliar que el drenaje percutáneo, ya que es superior en términos de viabilidad técnica, seguridad y eficacia en casos específicos de estenosis ampular e invasión duodenal. Además, puede ser realizada en países del tercer mundo, cuando se cuenta con el entrenamiento y los instrumentos adecuados. La endoprótesis metálica totalmente recubierta, aplicada a luz (HOT AXIOS stent, Xlumena Inc.; Mountain View, CA, Estados Unidos), es ideal para la colecistogastrostomía guiada por USE, a fin de minimizar complicaciones como fugas biliares. Se necesitan estudios comparativos adicionales para validar los beneficios de esta técnica.


Abstract The current treatment of malignant biliary obstruction is non-surgical biliary diversion with palliative intent. The surgery having specific indications in patients with malignant pathology with curative intent. However, duodenal obstruction and non-dilated intra- or extrahepatic bile duct make these surgical and endoscopic procedures guided by EUS difficult. We present our experience with the first case in Colombia, a third-world country in Latin America, of a cholecystogastrostomy guided by endoscopic ultrasound (EUS) in a patient with unresectable pancreatic cancer and duodenal invasion with dilated common bile duct using a luminal stent (LAMS) (HOT AXIOS stent, Xlumena Inc.; Mountain View, CA, USA) 15 mm × 10 mm. EUS-guided cholecystogastrostomy should be considered as an option for biliary decompression of greater importance than percutaneous drainage since it is superior in terms of technical feasibility, safety and efficacy in specific cases of ampullary stenosis and duodenal invasion. In addition, it can be done in third world countries when it has the appropriate training and implements. The fully covered metal stent applied to light (HOT AXIOS stent, Xlumena Inc.; Mountain View, CA, USA) is ideal for EUS guided cholecystogastrostomy to minimize complications such as bile leakage. Additional comparative studies are needed to validate the benefits of this technique.


Subject(s)
Humans , Male , Aged , Pancreatic Neoplasms , Therapeutics , Bile Ducts, Extrahepatic , Common Bile Duct , Endosonography , Methods , Drainage , Efficacy , Decompression
5.
Rev. Assoc. Med. Bras. (1992) ; 66(11): 1521-1525, Nov. 2020. graf
Article in English | SES-SP, LILACS, SES-SP | ID: biblio-1143633

ABSTRACT

SUMMARY INTRODUCTION: EUS-guided gastroenterostomy (EUS-GE) is a novel procedure for palliation of malignant gastric outlet obstruction (GOO). Our aim was to evaluate the outcomes of this technique in our initial experience. METHODS: Patients with GOO from our institute were included. Technical success was defined as the successful creation of a gastroenterostomy. Clinical success was defined as the ability to tolerate a soft diet after the procedure. We assessed adverse events and diet tolerance 1 month after the procedure. RESULTS: Three patients were included. Technical and clinical success was achieved in all cases. There were no adverse events and good diet tolerance was observed 1 month after the procedure in the included patients. CONCLUSION: EUS-GE is a promising treatment for patients with GOO.


RESUMO INTRODUÇÃO: A gastroenterostomia ecoguiada é um novo procedimento para paliação da obstrução maligna gastroduodenal. Nosso objetivo foi avaliar os resultados dessa técnica em nossa experiência inicial. MÉTODOS: Foram incluídos pacientes com obstrução maligna gastroduodenal de nossa instituição. O sucesso técnico foi definido como a realização adequada de uma gastroenterostomia. O sucesso clínico foi definido como boa aceitação de dieta pastosa durante a internação. Os eventos adversos e a aceitação alimentar foram avaliados um mês após o procedimento. RESULTADOS: Três pacientes foram incluídos. Os sucessos técnico e clínico foram alcançados em todos os casos. Não houve eventos adversos e a aceitação alimentar permaneceu adequada um mês após o procedimento nos pacientes incluídos. CONCLUSÃO: O EUS-GE é um tratamento promissor para pacientes com obstrução maligna gastroduodenal.


Subject(s)
Humans , Gastroenterostomy , Endosonography , Brazil , Stents , Gastric Outlet Obstruction/surgery , Gastric Outlet Obstruction/etiology , Gastric Outlet Obstruction/diagnostic imaging , Tertiary Care Centers
6.
Rev. colomb. gastroenterol ; 35(3): 319-328, jul.-set. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1138789

ABSTRACT

Resumen Introducción: la coledocolitiasis (CDL) afecta al 10 % de los pacientes con cálculos en la vesícula biliar. La obstrucción del colédoco se asocia a pancreatitis, colangitis y ruptura del colédoco. Clásicamente, la obstrucción biliar es considerada cuando se aumentan la fosfatasa alcalina, la γ-glutamil-transpeptidasa (GGTP) y las bilirrubinas. En la última década, se ha encontrado que hasta un 10 % de los pacientes con CDL presentan elevaciones de las aminotransferasas. En Latinoamérica, no se ha estudiado esta alteración. El objetivo del presente trabajo fue determinar la prevalencia de la elevación de transaminasas y su evolución. Metodología: estudio de casos y controles. Se determinó la alanina aminotransferasa (ALT) al ingreso, a las 48 h y a las 72 h. Si la ecografía era normal, se realizó una colangiorresonancia o una ecoendoscopia, así como una colangiopancreatografía retrógrada endoscópica (CPRE) cuando fue necesario. Resultados: se incluyeron 72 pacientes con CDL (casos) y 128 con colecistitis, sin CDL (controles). En los casos, el 83 % tuvo un aumento de ALT, mientras que el 56,9 % presentó una elevación de 2-9 veces, el 16 %, de 10-20 veces, y el 8,3 % mostró una elevación >20 veces. En contraste, a las 48 h, las ALT descendieron al 30 % y a las 72 h al 56 %. Entre tanto, en los controles hubo un aumento de ALT en el 27,3 %, mientras que en el 15,6 % se observó una elevación de 2-9 veces, en el 7,8 %, de 10-20 veces, y >20 veces en el 2,9 %. La combinación de cólico biliar y la elevación de ALT tuvo un valor predictivo positivo (VPP) para CDL del 72 %, así como un valor predictivo negativo (VPN) del 87,7 %. Conclusión: cuando hay un cólico biliar y una elevación de ALT es imperativo descartar una CDL, y si la ecografía es normal, es necesario realizar una colangiorresonancia o una ecoendoscopia biliopancreática.


Abstract Introduction: Choledocolithiasis (CLD) affects 10% of patients with gallstones. Bile duct obstruction is associated with pancreatitis, cholangitis, and rupture of the common bile duct. This condition usually presents with increased alkaline phosphatase, GGTP and bilirubin levels. In the last decade, it has been found that up to 10% of patients with CLD have elevated aminotransferases levels. In Latin America, this alteration has not been studied. The aim of the present work was to determine the prevalence of transaminase elevation and its evolution. Methodology: Case-control study. ALT was measured on admission, at 48 h and at 72 h. If ultrasound was normal, MRCP and/or echo-endoscopy and ERCP were performed, as appropriate. Results: A total of 72 patients with choledocholithiasis (CLD) (cases) and 128 with cholecystitis without choledocholithiasis (controls) were included. Among the cases, 83% had increased ALT levels, which was 2-9 times higher in 56.9%, 10-20 times higher in 16%, and more than 20 times higher in 8.3%. At 48 hours, those levels decreased by 30% and at 72 hours by 56%. In turn, in 27.3% of the controls, ALT was 2-9 times higher in 15.6%, 10-20 times higher in 7.8% and more than 20 times higher in 2.9%. The combination of biliary colic and ALT elevation had a positive predictive value (PPV) for CLD of 72% and a negative predictive value (NPV) of 87.7%. Conclusion: When biliary colic and ALT elevation are reported, it is imperative to rule out choledocholithiasis. If the ultrasound is normal, MRCP and/or biliopancreatic endoscopy should be performed.


Subject(s)
Humans , Case-Control Studies , Cholangiopancreatography, Endoscopic Retrograde , Lifting , Choledocholithiasis , Diagnosis , Alanine Transaminase , Transaminases , Colic , Endosonography
7.
Rev. Assoc. Med. Bras. (1992) ; 66(9): 1190-1195, Sept. 2020. graf
Article in English | SES-SP, LILACS, SES-SP | ID: biblio-1136370

ABSTRACT

SUMMARY Tubulovillous adenomas of the duodenal ampulla are rare neoplasms. The present report describes a case with radiological-endoscopic and pathological correlation in which the patient underwent duodenal pancreatectomy with good postoperative progression. With advanced imaging methods, especially magnetic resonance and endoscopic ultrasound, locoregional aspects and extraluminal, lymphovascular, and metastatic invasion have been increasingly discussed as contributors to therapeutic decision making. This progression improves lesion staging and is especially useful in selecting eligible candidates for endoscopic treatment.


RESUMO Os adenomas túbulo-vilosos da ampola duodenal são neoplasias raras. Neste trabalho apresentamos um caso com correlação radiológico-endoscópica e patológica, tendo a paciente sido submetida à duodenopancreatectomia com boa evolução pós-operatória. Com os avanços dos métodos de imagem, em especial da ressonância magnética e ultrassonografia endoscópica, aspectos locorregionais, além da invasão extraluminal, linfovascular e metastática, têm sido discutidos de maneira crescente como contribuintes na decisão terapêutica. Essa evolução contribui para o melhor estadiamento destas lesões e é especialmente útil para selecionar candidatos elegíveis ao tratamento endoscópico.


Subject(s)
Humans , Adenoma/surgery , Radiography , Endosonography , Duodenal Neoplasms , Endoscopy
8.
Rev. Assoc. Med. Bras. (1992) ; 66(9): 1210-1216, Sept. 2020. tab, graf
Article in English | SES-SP, LILACS, SES-SP | ID: biblio-1136359

ABSTRACT

SUMMARY OBJECTIVE: To evaluate the value of EBUS-TBNA in the diagnosis of lung and mediastinal lesions. METHODS: Prospective cohort study that included 52 patients during a 2-year period (2016 to 2018) who underwent EBUS-TBNA. RESULTS: Among the 52 individuals submitted to the procedure, 22 (42.31%) patients were diagnosed with locally advanced lung cancer (N2 or N3 lymph node involvement). EBUS-TBNA confirmed the diagnosis of metastases from other extrathoracic tumors in the mediastinum or lung in 5 patients (9.61%), confirmed small cell lung cancer in 3 patients (5.76%), mediastinal sarcoidosis in 1 patient (1.92%), and reactive mediastinal lymph node in 8 patients (15.38%); insufficient results were found for 3 patients (5.76%). Based on these results, EBUS-TBNA avoided further subsequent surgical procedures in 39 of 52 patients (75%). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 86%, 100%, 100%, 77%, and 90%, respectively. No major complications were observed. CONCLUSIONS: EBUS-TBNA is a safe, effective, and valuable method. This technique can significantly reduce the rate of subsequent surgical procedures required for the diagnosis of lung and mediastinal lesions.


RESUMO OBJETIVO: Avaliar a importância da ecoendoscopia endobrônquica com punção por agulha fina (Ebus-TBNA) no diagnóstico das lesões pulmonares e mediastinais. MÉTODOS: Estudo prospectivo e do tipo coorte, no qual foram incluídos 52 pacientes, durante o período de dois anos (2016 a 2018), submetidos ao procedimento de Ebus-TBNA. RESULTADOS: Do total de 52 indivíduos submetidos ao procedimento, 22 (42,31%) pacientes foram diagnosticados com neoplasia pulmonar localmente avançada (N2 ou N3). O método confirmou o diagnóstico de metástases de outros tumores extratorácicos no mediastino ou pulmão em cinco pacientes (9,61%), três pacientes (5,76%) com carcinoma de pequenas células, um paciente (1,92%) com sarcoidose, oito pacientes (15,38%) com linfonodomegalias reacionais/inflamatórias e resultado insuficiente em três pacientes (5,76%). O Ebus-TBNA evitou a realização de outros procedimentos cirúrgicos subsequentes em 39 de 52 (75%) pacientes. Foram calculados os valores de sensibilidade de 86%, especificidade de 100%, valor preditivo positivo de 100%, valor preditivo negativo de 77% e acurácia de 90%. Não foram observadas complicações maiores pelo método neste estudo. CONCLUSÃO: O Ebus-TBNA é um método seguro, eficaz e de relevante importância. Este exame pode reduzir significativamente o número de procedimentos invasivos subsequentes necessários para o diagnóstico das lesões pulmonares e mediastinais.


Subject(s)
Humans , Endosonography , Mediastinum/diagnostic imaging , Prospective Studies , Ultrasonography, Interventional , Neoplasm Staging
9.
Rev. cuba. cir ; 59(2): e917, abr.-jun. 2020. graf
Article in Spanish | LILACS, CUMED | ID: biblio-1126418

ABSTRACT

RESUMEN La exploración mediastinal comienza desde la época de Galeno. Su desarrollo se alcanzó en la segunda mitad del siglo XX, utilizada para el estudio de los ganglios y tumores mediastinales. En la actualidad su uso se ha ampliado no solo como diagnóstico, sino con fines terapéuticos, al lograr realizar resecciones pulmonares. El objetivo es realizar una revisión actualizada de la literatura, acerca del uso de la mediastinoscopia en el diagnóstico del cáncer pulmonar. Se realizó una revisión de la literatura médica donde se utilizaron las bases de datos Scopus, Medline y Cochrane bajo los criterios de sus revisores. Se emplearon las palabras claves en idioma español e inglés. El método de análisis y síntesis se usó para la interpretación de la bibliografía. Se revisaron 173 artículos, de los cuales, se escogieron 58, que cumplían con los criterios de selección, entre ellos, 6 meta análisis, 11 artículos de revisión y 41 artículos originales. La videomediastinoscopía constituye una herramienta válida para el diagnóstico, así como para el estadiamiento de enfermedades dentro y fuera de la cavidad torácica y mediastino. Por otra parte, permite el tratamiento de algunas enfermedades(AU)


ABSTRACT The mediastinal exploration begins from the time of Galen. Its development was reached in the second half of the 20th century, used for the study of lymph nodes and mediastinal tumors. At present its use has been expanded not only as a diagnosis, but also for therapeutic purposes, by achieving lung resections. The objective is to carry out an updated review of the literature on the use of mediastinoscopy in the diagnosis of lung cancer. A review of the medical literature was carried out where the Scopus, Medline and Cochrane databases were used under the criteria of their reviewers. The keywords in Spanish and English were used. The method of analysis and synthesis was used for the interpretation of the bibliography. 173 articles were reviewed, of which 58 were chosen, which met the selection criteria, including 6 meta-analyzes, 11 review articles, and 41 original articles. Videomediastinoscopy is a valid tool for diagnosis, as well as for the staging of diseases inside and outside the thoracic cavity and mediastinum. On the other hand, it allows the treatment of some diseases(AU)


Subject(s)
Humans , Endosonography/methods , Thoracic Surgery, Video-Assisted/methods , Lung Neoplasms/diagnostic imaging , Mediastinoscopy/methods , Review Literature as Topic
10.
Medicina (B.Aires) ; 80(2): 173-176, abr. 2020. ilus
Article in Spanish | LILACS | ID: biblio-1125061

ABSTRACT

El cáncer de pulmón es la principal causa de muerte por cáncer en todo el mundo. Los nódulos pulmonares ubicados en proximidad al mediastino, retrocardíacos, cercanos a grandes vasos o por delante de la columna vertebral pueden resultar de difícil acceso por vía percutánea o broncoscópica. La punción aspiración/biopsia con aguja fina guiada por ecoendoscopía transesofágica (EUS-FNA/FNB) es un método mini invasivo con baja morbilidad que permitiría acceder a estas localizaciones. Presentamos el caso de un paciente con nódulo pulmonar solitario, en el que se obtuvo el diagnóstico de cáncer de pulmón mediante EUS-FNA/FNB.


Lung cancer is one of the leading causes of death worldwide. Pulmonary nodules located in the vicinity of the mediastinum, retrocardiac, near the aorta or pulmonary vessels, and in front of the spine, may be difficult to access through a percutaneous or bronchoscopic approach. Fine needle aspiration/biopsy guided by transesophageal echoendoscopy (EUS-FNA/FNB) is a minimally invasive method with low morbidity that could allow access to lesions in these places. We present the case of a patient with a solitary pulmonary nodule, in which the diagnosis of lung cancer was obtained by EUS-FNA/FNB.


Subject(s)
Humans , Male , Aged, 80 and over , Carcinoma, Squamous Cell/pathology , Endoscopic Ultrasound-Guided Fine Needle Aspiration/methods , Lung Neoplasms/pathology , Carcinoma, Squamous Cell/radiotherapy , Tomography, X-Ray Computed , Endosonography , Biopsy, Fine-Needle , Lung Neoplasms/radiotherapy
11.
Gastroenterol. latinoam ; 31(2): 85-89, 2020. ilus
Article in Spanish | LILACS | ID: biblio-1292373

ABSTRACT

Subepithelial lesions are generally an incidental diagnosis with an prevalence of 0.4%. These tumors represent a great diagnostic challenge, mainly when ruling out potentially malignant lesions, such as gastrointestinal stromal tumor (GIST), lymphomas and carcinomas. Among the many differential diagnosis, the ectopic pancreas arises with an prevalence of 1-2% in general population. The first diagnostic approach is performed using upper digestive endoscopy, computed tomography and endosonography. This last one has a diagnostic performance of less than 50%, which increases to 90% when it is associated with a histopathological examination. There is no current consensus regarding the management and monitoring of these lesions. Based on the imaging and histological characteristics, the possibilities range from observation to endoscopic or surgical resection. In this context, we will present a clinical case of ectopic pancreas as an incidental finding, and afterwards the diagnostic and therapeutic breakdown of subepithelial lesions.


Las lesiones subepiteliales son pesquisadas generalmente de manera incidental, con una prevalencia de 0,4%. Estos tumores suponen un gran desafío diagnóstico, principalmente al momento de descartar lesiones potencialmente malignas, como el tumor estromal gastrointestinal (GIST), linfomas y carcinomas. Dentro de los posibles diagnósticos, surge el páncreas ectópico, con una prevalencia de hasta 1-2% en la población general. La primera aproximación diagnóstica se realiza mediante endoscopia digestiva alta, tomografía computarizada y la endosonografía, ésta última con un rendimiento diagnóstico menor del 50%, que aumenta hasta el 90% al asociar el examen histopatológico. No existe consenso actual respecto al manejo y seguimiento de estas lesiones, que según sus características imagenológicas e histológicas, va desde la observación hasta la resección endoscópica o quirúrgica. En este contexto, se presenta un caso clínico de páncreas ectópico como hallazgo incidental y el desglose diagnóstico y terapéutico de las lesiones subepiteliales.


Subject(s)
Humans , Male , Adult , Pancreas/diagnostic imaging , Choristoma/diagnostic imaging , Stomach Diseases/diagnosis , Endosonography , Gastrointestinal Stromal Tumors/diagnosis , Diagnosis, Differential , Gastrointestinal Neoplasms/diagnosis
12.
ABCD arq. bras. cir. dig ; 33(2): e1512, 2020. tab, graf
Article in English | LILACS | ID: biblio-1130523

ABSTRACT

ABSTRACT Background: Gastrointestinal neuroendocrine tumors are rare, usually presented as subepithelial or polypoid tumors. Accurate diagnosis and indication of the type of resection are still challenging. Aim: To determine the effectiveness of echoendoscopy in determining the depth of the lesions (T) identified by endoscopy in order to evaluate surgical and/or endoscopic indication, and to evaluate the results of endoscopic removal in the medium term. Methods: Twenty-seven patients were included, all of whom underwent echoendoscopy for TN tumor staging and the evaluation of possible endoscopic resection. The parameters were: lesion size, origin layer, depth of involvement and identified perilesional adenopathies. The inclusion criteria for endoscopic resection were: 1) high surgical risk; 2) those with NET <2 cm; 3) absence of impairment of the muscle itself; and 4) absence of perilesional adenopathies in echoendoscopy and in others without distant metastases. Exclusion criteria were TNE> 2 cm; those with infiltration of the muscle itself; with perilesional adenopathies and distant metastases. The techniques used were: resection with polypectomy loop; mucosectomy with saline injection; and mucosectomy after ligation with an elastic band. The anatomopathological study of the specimens included evaluation of the margins and immunohistochemistry (chromogranin, synaptophysin and Ki 67) to characterize the tumor. Follow-up was done at 1, 6 and 12 months. Results: Resections with polypectomy loop were performed in 15 patients; mucosectomy in five; mucosectomy and ligation with elastic band in three and the remaining four were referred for surgery. The anatomopathological specimens and immunohistochemical analyzes showed positive chromogranin and synaptophysin, while Ki 67 was less than 5% among all cases. The medium-term follow-up revealed three recurrences. The average size of tumors in the stomach was 7.6 mm and in the duodenum 7.2 mm. Well-demarcated, hypoechoic, homogeneous lesions occurred in 75%; mucous layer in 80%; and the deep and submucosal mucosa in 70%. Conclusions: Echoendoscopy proved to be a good method for the study of subepithelial lesions, being able to identify the layer affected by the neoplasm, degree of invasion, echogenicity, heterogeneity, size of the lesion and perilesional lymph node involvement and better indicate the treatment option.


RESUMO Racional: Tumores neuroendócrinos gastrointestinais são raros geralmente apresentados como tumores subepiteliais ou polipoides. O diagnóstico preciso e a indicação do tipo de ressecção ainda são desafiadores. Objetivo: Determinar a eficácia da ecoendoscopia em determinar a profundidade das lesões (T) identificadas pela endoscopia com objetivo de avaliar indicação cirúrgica e/ou endoscópica, e avaliar os resultados da remoção endoscópica em seguimento em médio prazo. Métodos: Foram incluídos 27 pacientes todos submetidos à ecoendoscopia para estadiamento tumoral TN e à avaliação de possível ressecção endoscópica. Os parâmetros estudados foram: tamanho da lesão, camada de origem, profundidade do acometimento e adenopatias perilesionais identificadas. Os critérios de inclusão para ressecção endoscópica foram: 1) risco cirúrgico elevado; 2) aqueles com TNE <2 cm; 3) ausência de comprometimento da muscular própria; e 4) ausência de adenopatias perilesionais na ecoendoscopia e em outros sem metástases à distância. Os critérios de exclusão foram TNE >2 cm; os com infiltração da muscular própria; com adenopatias perilesionais e metástases à distância. As técnicas utilizadas foram: ressecção com alça de polipectomia; mucosectomia com injeção de solução salina; e mucosectomia após a ligadura com banda elástica. O estudo anatomopatológico dos espécimes incluiu avaliação das margens e imunoistoquímica (cromogranina, sinaptofisina e Ki 67) para caracterizar o tumor. O seguimento foi feito com 1, 6 e 12 meses. Resultados: Ressecções com alça de polipectomia foram realizadas em 15 pacientes; mucosectomia em cinco; mucosectomia e ligadura com banda elástica em três e os quatro restantes foram encaminhados para cirurgia. O anatomopatológico dos espécimes e as análises imunoistoquímicas mostraram cromogranina e sinaptofisina positivas, enquanto que o Ki 67 foi menor que 5% dentre todos os casos. O seguimento em médio prazo revelou três recidivas. A média de tamanho dos tumores no estômago foi de 7,6 mm e no duodeno 7,2 mm. As lesões bem demarcadas, hipoecóicas, homogêneas ocorreram em 75%; da camada mucosa em 80%; e da mucosa profunda e submucosa em 70%. Conclusões: A ecoendoscopia mostrou ser bom método para o estudo de lesões subepiteliais podendo identificar a camada acometida pela neoplasia, grau de invasão, ecogeneicidade, heterogeneidade, tamanho da lesão e acometimento linfonodal perilesional e melhor indicar a opção de tratamento.


Subject(s)
Humans , Neuroendocrine Tumors/surgery , Neuroendocrine Tumors/diagnostic imaging , Endosonography/methods , Gastrointestinal Neoplasms/surgery , Gastrointestinal Neoplasms/diagnostic imaging , Treatment Outcome , Neuroendocrine Tumors/pathology , Gastrointestinal Neoplasms/pathology , Neoplasm Recurrence, Local , Neoplasm Staging
13.
Rev. colomb. gastroenterol ; 34(4): 337-344, oct.-dic. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1092959

ABSTRACT

Resumen La ultrasonografía endoscópica (USE) se usa ampliamente para evaluar enfermedades pancreatobiliares, especialmente masas pancreáticas. La USE tiene una buena capacidad para detectar masas pancreáticas, pero no es suficiente para el diagnóstico diferencial de varios tipos de lesiones. La aspiración endoscópica con aguja fina guiada por ultrasonido (USE-PAF) es el método de diagnóstico de elección para masas pancreáticas y su precisión se afecta por diversos métodos de punción. Materiales y métodos: nuestro objetivo fue evaluar el rendimiento diagnóstico de la técnica de succión estándar (TS) versus la técnica húmeda híbrida (TH) en el estudio de lesiones sólidas en páncreas, utilizando un diseño prospectivo, con ocultación única, aleatorizado y controlado, que incluye a pacientes con diagnóstico de lesión sólida en páncreas a los que se realizó USE-PAF desde mayo de 2014 a junio de 2016. Resultados: en total incluimos 65 pacientes, 34 (52,3%) se asignaron a USE-PAF con TH y 31 (47,7%) pacientes a USE-PAF con TS. Se encontró que la frecuencia relativa porcentual respecto a la técnica de punción en la USE-PAF en lesiones sólidas de páncreas, que permite obtener la cantidad de tejido adecuado para el diagnóstico citológico, fue de 85,2% para la TH y 71% para la TS, con un OR de 2,35 (IC 95%; 1,2-4,7) a favor de la TH. Conclusión: este estudio sugiere que la TH es superior a la TS en el diagnóstico de las lesiones sólidas del páncreas, por lo cual, dado que la implementación de esta técnica no aumenta costos y es muy sencilla, sugerimos que sea la técnica de elección cuando se necesita puncionar una lesión sólida.


Abstract Endoscopic ultrasound (EUS) is widely used to evaluate pancreatobiliary diseases, especially pancreatic masses. EUS has a good ability to detect pancreatic masses, but it is not sufficient for differential diagnoses of various types of lesions. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is the diagnostic method of choice for pancreatic masses, but its accuracy is affected by various puncture methods. Materials and methods: Our objective was to compare the diagnostic yield of examinations of solid lesions in the pancreas by the standard suction technique (ST) with the yield of the hybrid technique (HT) using a prospective, single blind, randomized, controlled design. Patients diagnosed with solid pancreatic lesions who underwent EUS-FNA from May 2014 to June 2016 were included. Results: We included 65 patients, 34 of whom (52.3%) were assigned to EUS-FNA with HT, and 31 of whom (47.7%) were assigned to EUS-FNA with TS. We found that the relative frequency that HT successfully obtained an adequate amount of tissue for the cytological diagnosis was 85.2% while ST's relative frequency of success was 71%. The odds ratio was 2.35 (95% CI; 1.2-4.7) in favor of HT. Conclusion: This study suggests that the TH is superior to ST for diagnosis of solid pancreatic lesions. Since implementation of this technique does not increase costs and is very simple, we suggest that it become the technique of choice for EUS-FNA.


Subject(s)
Humans , Male , Female , Pancreas , Endoscopic Ultrasound-Guided Fine Needle Aspiration , Methods , Ultrasonics , Endosonography
14.
Rev. colomb. gastroenterol ; 34(3): 231-236, jul.-set. 2019. graf
Article in Spanish | LILACS | ID: biblio-1042809

ABSTRACT

Resumen La dispepsia se define como un dolor o molestia abdominal superior que se considera originado en el tracto gastrointestinal superior. Muchas enfermedades y condiciones clínicas pueden producir dispepsia como la úlcera péptica, cáncer gástrico o esofágico, medicamentos, litiasis biliar, pancreatitis, cáncer de páncreas, entre otras. Por una parte, tradicionalmente la dispepsia solo se evalúa con la endoscopia digestiva y su producción solo es del 27 %. Por otra parte, la ecoendoscopia (ECE), al combinar una imagen endoscópica y una imagen ecográfica, podría ampliar el rango diagnóstico al detectar más causas de dispepsia que puedan ayudar a tratar al paciente de manera más oportuna. Objetivo: evaluar si la ECE aumenta el rendimiento diagnóstico que tiene la endoscopia (27 % en nuestro medio) en el enfoque inicial de la dispepsia no investigada (DPNI). Materiales y métodos: estudio prospectivo, de prevalencia analítica en pacientes adultos con DPNI, que consultaron a una institución universitaria de Colombia. Los pacientes incluidos consultaron a la unidad de gastroenterología durante el período comprendido entre enero a octubre del 2016 y se programaron para endoscopia digestiva alta (EDA). Bajo sedación guiada por anestesiólogo primero se realizó la fase endoscópica evaluando el esófago, estómago y duodeno; después se realizó la fase ecográfica y se inició el examen de manera retrógrada evaluándose el páncreas en su totalidad, la vía biliar extrahepática, la vesícula biliar, el tronco celíaco, el lóbulo izquierdo del hígado y la región mediastinal. Todas las anormalidades se anotaban en el formulario de ingreso del paciente. Resultados: En total se incluyeron a 60 pacientes, de los cuales el 65 % son de sexo femenino con un promedio de edad de 40,8 (desviación estándar: 12,5). Los hallazgos en la fase endoscópica de la ECE fueron principalmente gastritis crónica en 43 pacientes (71,6 %), el resto tenía una lesión estructural (17 pacientes): esofagitis en 5 (8,3 %), úlcera gástrica en 2 (3,3 %), úlcera duodenal en 5 (8,3 %), cáncer gástrico en 4 (6,6 %) y lesión subepitelial gástrica (GIST) en 1 (1,6 %). Los hallazgos en la fase ecográfica de la ECE fueron colelitiasis en 11 (18,3 %), coledocolitiasis en 1 (1,6 %) y pancreatitis crónica en 5 (8,3 %). Aunque solo el 28,3 % (17) de los pacientes con dispepsia tuvo un hallazgo estructural en la fase endoscópica, 18 pacientes (30 %) presentaron algún hallazgo positivo en la fase ecográfica, es decir que el rendimiento subió a un 58,3 % (p <0,001). Conclusión: este estudio, aunque pequeño, sugiere que la ECE como método inicial de enfoque en la evaluación de la dispepsia podría llegar a ser útil dado que aumenta el rendimiento diagnóstico en este grupo de pacientes, pasando de un 28,3 % a 58,3 %, lo cual es muy significativo si se tiene en cuenta que estos pacientes con dispepsia y endoscopia negativa usualmente se catalogan como funcionales y solo se les formula medicamentos. Sin embargo, se deben reconocer las fallas metodológicas del estudio y consideramos que es una exploración inicial y deben plantearse estudios más grandes y controlados para confirmar este trabajo; además, se debe tener en cuenta el costo del examen, que es mucho mayor que el de la EDA.


Abstract Dyspepsia is defined as upper abdominal pain or discomfort that is considered to originate in the upper gastrointestinal tract. Many diseases and clinical conditions can cause dyspepsia. Among others, they include peptic ulcers, gastric and esophageal cancer, medications, biliary lithiasis, pancreatitis, and pancreatic cancer. Traditionally, dyspepsia is only evaluated with digestive endoscopy whose diagnostic yield is only 27%. On the other hand, endoscopic ultrasound combines an endoscopic image and an ultrasound image thereby potentially broadening diagnostic range to detect more of the causes of dyspepsia allowing treatment of patients in a timelier manner. Objective: To evaluate whether endoscopic ultrasound increases the diagnostic yield of endoscopy (27% in our environment) in the initial approach to previously unstudied dyspepsia. Materials and methods: This is a prospective study of analytical prevalence in adult patients with previously unstudied dyspepsia who were examined at a university institution in Colombia. The patients included were seen in the gastroenterology unit from January to October 2016 and underwent upper digestive endoscopy and endoscopic ultrasound. Under anesthesiologist-guided sedation, the stomach and duodenal esophagus were first evaluated endoscopically. Then retrograde endoscopic ultrasound was used to evaluate the pancreas in its entirety, the extra hepatic bile duct, the gallbladder, the celiac trunk, the left lobe of the liver and the mediastinal region. All abnormalities were noted on the patient's admission form. Results: In total we included 60 patients of whom 65% were female and whose average age of was 40.8 years (SD: 12.5). The findings in the endoscopic phase of the endoscopic ultrasound were mainly chronic Gastritis 43 patients (71.6%), the rest had a structural lesion (17 patients): esophagitis 5 (8.3%), gastric ulcer 2 (3.3%), duodenal ulcer 5 (8.3%), gastric cancer, 4 (6.6%), gastric subepithelial lesion (GIST) 1 (1.6%). In the endoscopy phase, we found 11 cases of cholelithiasis (18.3%), one case of choledocholithiasis (1.6%), and five cases of chronic pancreatitis (8.3%). Only 17 patients of these patients (28.3%) had a structural finding in the endoscopy phase, but 18 additional patients (30%) had some positive finding in the ultrasound phase. In other words, the diagnostic yield rose to 58.3% (p < 0.001). Conclusion: Although this study's sample size is small, it suggests that using endoscopic ultrasound in the initial evaluation of dyspepsia could be useful since it increased diagnostic yield in this group of patients from 28.3 to 58.3%. This is very significant because patients with dyspepsia and negative endoscopy are usually classified as functional and only treated with medications. However, in recognition of the methodological limitations of this study, it should be considered an initial exploration. Larger, controlled studies should be considered to confirm this work. Another factor that should be considered is the cost of endoscopic ultrasound which is much higher than the upper digestive endoscopy.


Subject(s)
Humans , Population , Prospective Studies , Endosonography , Dyspepsia , Endoscopy
15.
Rev. Assoc. Med. Bras. (1992) ; 65(8): 1055-1060, Aug. 2019. tab, graf
Article in English | LILACS | ID: biblio-1041056

ABSTRACT

SUMMARY OBJECTIVE This study aims to investigate the causes of misdiagnosis in assessing tubal patency by transvaginal real-time three-dimensional hysterosalpingo-contrast sonography (TVS RT-3D-HyCoSy), in order to improve the diagnostic efficiency of TVS RT-3D-HyCoSy. METHODS A total of 162 oviducts of 83 infertility patients were examined by TVS RT-3D-HyCoSy. These results were compared with the gold standard for laparoscopic dye studies, and the misdiagnosed cases were analyzed. RESULTS TVS RT-3D-HyCoSy revealed that 68 oviducts were unobstructed and 94 obstructed. The results for the 144 oviducts were in line with the gold standard, while those for 18 oviducts were not. The accuracy rate of the TVS RT-3D-HyCoSy was 88.9%, and the misdiagnosis rate was 11.1%. The main causes of misdiagnosis included contrast medium countercurrent and diffusion, oviduct spasm, abnormal shape or position of the oviduct, pelvic adhesion, and poor imaging operation. CONCLUSION TVS RT-3D-HyCoSy can well-evaluate tubal patency, and understand and improve the cause of misdiagnosis. Furthermore, the diagnostic efficiency of TVS RT-3D-HyCoSy can still be further improved.


RESUMO OBJETIVO Este estudo tem como objetivo investigar as causas do diagnóstico equivocado na avaliação da patência tubária por meio da ultrassonografia de contraste histerosalpingo em tempo real transvaginal (TVS RT-3D-HyCoSy), a fim de melhorar a eficiência diagnóstica das TVS RT-3D-HyCoSy. MÉTODOS Um total de 162 ovidutos em 83 pacientes da infertilidade foi examinado por TVS RT-3D-HyCoSy. Esses resultados foram comparados com o padrão ouro para estudos de tintura laparoscópica, e os casos diagnosticados erroneamente foram analisados. RESULTADOS TVS RT-3D-HyCoSy revelaram que 68 ovidutos foram desobstruídos e 94 ovidutos foram obstruídos. Os resultados para os 144 ovidutos estavam em consonância com o padrão ouro, enquanto que aqueles para os 18 ovidutos, não. A taxa de acurácia do TVS RT-3D-HyCoSy foi de 88,9%, e a taxa de erro de diagnóstico foi de 11,1%. As principais causas de erro de diagnóstico incluíram contraponto e difusão do meio de contraste, espasmo do oviduto, forma ou posição anormal do oviduto, adesão pélvica e má operação de imagem. CONCLUSÃO TVS RT-3D-HyCoSy pode bem avaliar a patência tubária, e compreender e melhorar a causa do erro de diagnóstico. Além disso, a eficiência diagnóstica do TVS RT-3D-HyCoSy ainda pode ser melhorada.


Subject(s)
Humans , Female , Adult , Young Adult , Fallopian Tubes/diagnostic imaging , Infertility, Female/diagnostic imaging , Hysterosalpingography , Risk Factors , Endosonography , Imaging, Three-Dimensional , Diagnostic Errors , Fallopian Tube Patency Tests/methods , Middle Aged
16.
Rev. argent. coloproctología ; 30(2): 51-56, Jun. 2019. tab
Article in Spanish | LILACS | ID: biblio-1025473

ABSTRACT

Introducción: La incontinencia anal es una compleja y devastadora patología que altera la calidad de vida de los pacientes, cuya etiología más común es la lesión esfintérica postparto vaginal. A la hora de clasificar la incontinencia, el score descripto por Jorge y Wexner es el más utilizado en nuestro medio. La ecografía endoanal ha sido definida como el gold standard para evaluar los defectos del esfínter anal. Objetivo: Determinar la correlación entre los hallazgos clínicos y ecográficos en pacientes con incontinencia fecal de causa obstétrica. Material y Métodos: Población: pacientes que consultaron en el Centro Privado de Cirugía y Coloproctología entre enero de 2015 y diciembre de 2017 por incontinencia fecal con antecedentes de trauma obstétrico y a las que se les realizó una ecografía endoanal 360° y score de Jorge y Wexner. Resultados: Se evaluaron 24 pacientes. La media de edad fue de 56 años. El número de partos en promedio fue 2,3 y el Score de Wexner en promedio fue 9.7 (±5.2). La ecografía endoanal confirmó alteración esfintérica por afinamiento o interrupción en el 100% de los pacientes. Se observó una tendencia a una asociación negativa entre el Score de Wexner y la ecografía endoanal (r=-0.328, p=0.067). Las pacientes con menor grado de lesión esfinteriana por ecografía tenían mayor severidad en el Score de Wexner que las pacientes con mayor grado de lesión. Las pacientes con evidencia ecográfica de lesiones leves refirieron un mayor Score de Wexner que aquellas con lesiones severas. Conclusión: En este trabajo no existió correlación entre los hallazgos ecográficos y el score de incontinencia. Si bien la ecografía esfintérica es el gold standard para evaluar daño muscular, la terapéutica no debe ser determinada solamente por la ecografía. Tipo de estudio: Retrospectivo, transversal y descriptivo.


Introduction: Anal incontinence is a complex and devastating pathology that alters the patient's quality of life, whose most common etiology is vaginal postpartum sphincter injury. To classify incontinence, the score described by Jorge and Wexner is the most used in our environment. Endoanal ultrasound has been defined as the gold standard for evaluating anal sphincter defects. Objective: To determine the correlation between clinical and ultrasound findings in patients with fecal incontinence due to obstetric cause. Material and Methods: Population: patients who consulted at the Private Center of Surgery and Coloproctology between January 2015 and December 2017 due to fecal incontinence with a history of obstetric trauma and who underwent a 360º endoanal ultrasound and a Jorge and Wexner score. Results: Twenty-four patients were evaluated. The average age was 56 years. The number of births on average was 2.3 and the Wexner Score on average was 9.7 (± 5.2). Endoanal ultrasound confirmed sphincter alteration by refining or interruption in 100% of patients. A tendency to a negative association was observed between the Wexner Score and the endoanal ultrasound (r = -0.328, p = 0.067). Patients with a lower degree of sphincter injury by ultrasound had greater severity in the Wexner Score than patients with a higher degree of injury. Patients with ultrasound evidence of mild lesions reported a higher Wexner Score than those with severe lesions. Conclusion: In this work, there was no correlation between the sonographic findings and the incontinence score. Although sphincter ultrasonography is the gold standard for assessing muscle damage, therapy should not be determined only by ultrasound. Type of study: Retrospective, cross-sectional and descriptive.


Subject(s)
Humans , Female , Pregnancy , Adult , Middle Aged , Aged , Aged, 80 and over , Anal Canal/injuries , Anal Canal/diagnostic imaging , Endosonography/methods , Fecal Incontinence/etiology , Risk Factors , Fecal Incontinence/diagnostic imaging , Obstetric Labor Complications
17.
Rev. colomb. gastroenterol ; 34(2): 197-201, abr.-jun. 2019. graf
Article in Spanish | LILACS | ID: biblio-1013936

ABSTRACT

Resumen Se presenta el caso clínico de un paciente masculino de 74 años quien ingresó con síntomas de sangrado digestivo alto, se realizó una endoscopia de vías digestivas altas y se encontraron dos lesiones en el estómago: una elevada de centro ulcerado y otra subepitelial, lo que llevó a completar los estudios con una ecoendoscopia gástrica que mostró una lesión mucosa que infiltraba la submucosa sugestiva de cáncer gástrico temprano y otra lesión subepitelial dependiente de la muscular, sugestivas de un tumor gastrointestinal estromal (GIST); los estudios de estatificación no evidenciaron compromiso metastásico, por lo que se llevó al manejo quirúrgico con la posterior confirmación histológica de los hallazgos.


Abstract We present the case of a 74-year-old male patient who was admitted with symptoms of upper digestive bleeding. Endoscopy of his upper digestive tract found an ulcerated lesion and a subepithelial lesion in his stomach. Complete studies including gastric endoscopic ultrasound showed a mucosal lesion infiltrating the submucosa which was suggestive of early gastric cancer as well as a subepithelial lesion on the muscle that was suggestive of a gastrointestinal stromal tumor (GIST). Staging showed no metastatic compromise, so surgery was performed, and histology subsequently confirmed the findings.


Subject(s)
Humans , Male , Aged , Stomach Neoplasms , Gastrointestinal Stromal Tumors , Endosonography , Endoscopy , Mucous Membrane
18.
Rev. Assoc. Med. Bras. (1992) ; 65(5): 589-591, May 2019. graf
Article in English | LILACS | ID: biblio-1012970

ABSTRACT

SUMMARY Our case report shows the complexity of dealing with tracheal tumors, highlighting the importance of the method used for staging. In this report, endoscopic ultrasound (EUS) was crucial to identify the involvement of the esophageal muscular propria in a tracheal tumor and change the surgical planning of the case. Staging this kind of tumor represents a challenge for physicians. There is no evidence in the literature on which methods represent the gold standard for T staging.


RESUMO Neste relato de caso mostramos a complexidade em lidar com tumores traqueais, destacando a importância do método usado para estadiamento. Neste relato, a ecoendoscopia (EUS) foi fundamental para identificar o envolvimento da camada muscular própria esofágica por um tumor traqueal e alterar o planejamento cirúrgico do caso. O estadiamento desse tipo de tumor representa um desafio para os médicos. Não há evidências na literatura sobre quais métodos representam o padrão ouro para o estadiamento T.


Subject(s)
Humans , Male , Aged , Tracheal Neoplasms , Carcinoma, Squamous Cell/diagnostic imaging , Endosonography/methods , Bronchoscopy/methods , Esophageal Neoplasms/pathology , Esophageal Neoplasms/diagnostic imaging , Tracheal Neoplasms/pathology , Carcinoma, Squamous Cell/pathology , Positron Emission Tomography Computed Tomography , Neoplasm Staging
19.
Oncol. (Guayaquil) ; 29(1): 67-73, 30 de abril 2019.
Article in Spanish | LILACS | ID: biblio-1005066

ABSTRACT

Introducción: La aparición de nuevas técnicas de imagen y mayor conocimiento de esta entidad han contribuido para que el diagnóstico del Tumor Mucinoso Papilar Intraductal haya aumentado en la última década. En el presente artículo describimos un caso de un paciente con Tumor Mucinoso Papilar Intraductal de páncreas, hallazgo incidental en Tomografía computarizada de abdomen. Caso Clínico: Se trata de una mujer de 71 años de edad, con antecedentes de Diabetes tipo 2, Hipertensión Arterial Esencial, y cáncer de mama intervenida. En un estudio de control con tomografía computarizada de abdomen se observó un tumor pancreático de 3 x 1.1 cm. Se realizó una punción transagástrica, con lo que se obtuvo una muestra para estudio patológico, el cual reportó una neoplasia mucinosa papilar intraductal. Evolución: La paciente fue sometida a cirugía con la Técnica de Whipple, con duodenopancreatectomía, en donde se retiró la cabeza del páncreas con el tumor adyacente. El estudio de patología confirmó una neoplasia mucinosa papilar intraductal. La paciente no presentó complicaciones post-operatorias y continúa en revisión en consulta externa. Conclusión: Por tratarse de una lesión maligna, el diagnóstico oportuno y correcto fue importante en este caso, para la conducta terapéutica quirúrgica resolutiva.


Introduction: The appearance of new imaging techniques and greater knowledge of this entity have contributed to the diagnosis of the Mucinous Papular Intraductal Tumor has increased in the last decade. In the present article, we describe a case of a patient with pancreatic papillary intraductal mucosal tumor, incidental finding in abdominal CT scan. Clinical Case: This is a 71-year-old woman with a history of type 2 diabetes, essential arterial hypertension, and intervened breast cancer. In a control study with abdominal CT, a pancreatic tumor of 3 x 1.1 cm was observed. A transgastric puncture was performed, which obtained a sample for pathological study, which reported an intraductal papillary mucinous neoplasia. Evolution: The patient underwent surgery with the Whipple Technique, with pancreaticoduodenectomy, in which the head of the pancreas with the adjacent tumor was removed. The pathology study confirmed an intraductal papillary mucinous neoplasm. The patient did not present post-operative complications and continues in external consultation review. Conclusion: Because it is a malignant lesion, the opportune and correct diagnosis was important in this case, for the operative surgical therapeutic behavior.


Subject(s)
Humans , Pancreatic Neoplasms , Case Reports , Carcinoma, Pancreatic Ductal , General Surgery , Tomography , Endosonography
20.
Arq. gastroenterol ; 56(1): 99-105, Jan.-Mar. 2019. tab, graf
Article in English | LILACS | ID: biblio-1001334

ABSTRACT

ABSTRACT BACKGROUND: One of the most feared complications with the use of cyanoacrylate for treatment of gastric varices is the occurrence of potentially life-threatening systemic embolism. Thus, endoscopists are turning towards new techniques, including endoscopic coiling, as a potentially safer and more effective treatment option. However, no studies have been performed comparing the two techniques. OBJECTIVE: This study aims to compare the safety and efficacy of endoscopic ultrasound guided coil and cyanoacrylate injection versus the conventional technique of injection of cyanoacrylate alone. DESIGN: A pilot randomized controlled trial. METHODS: Patients randomized into group I were treated with coil and cyanoacrylate, and those in group II with cyanoacrylate alone. Flow within the varix was evaluated immediately after the treatment session and one month following initial treatment. If thrombosis was confirmed, additional follow-up was performed 4 and 10 months following initial treatment. All patients underwent a thoracic computerized tomography scan after the procedure. RESULTS: A total of 32 patients, 16 in each group, were followed for an average of 9.9 months (range 1-26 months). Immediately after the procedure, 6 (37.5%) group-I patients and 8 (50%) group-II patients presented total flow reduction in the treated vessel (P=0.476). After 30 days, 11 (73.3%) group-I patients and 12 (75%) group-II patients were found to have varix thrombosis. In both groups, the majority of patients required only one single session for varix obliteration (73.3% in group I versus 80% in group II). Asymptomatic pulmonary embolism occurred in 4 (25%) group-I patients and 8 (50%) group-II patients (P=0.144). No significant difference between the groups was observed. CONCLUSION: There is no statistical difference between endoscopic ultrasound guided coils plus cyanoacrylate versus conventional cyanoacrylate technique in relation to the incidence of embolism. However, a greater tendency towards embolism was observed in the group treated using the conventional technique. Both techniques have similar efficacy in the obliteration of varices. Given the small sample size of our pilot data, our results are insufficient to prove the clinical benefit of the combined technique, and do not yet justify its use, especially in light of higher cost. Further studies with larger sample size are warranted.


RESUMO CONTEXTO: Uma das complicações mais temidas com o uso de cianoacrilato para tratamento de varizes gástricas é a ocorrência de embolia sistêmica potencialmente fatal. Assim, os endoscopistas estão se aprimorando com novas técnicas, incluindo o uso de coils endoscópico, como uma opção de tratamento potencialmente mais segura e eficaz. No entanto, nenhum estudo foi realizado comparando as duas técnicas. OBJETIVO: Este estudo tem como objetivo comparar a segurança e eficácia da injeção de coil com cianoacrilato guiados por ultrassom endoscópico versus a técnica convencional de injeção de cianoacrilato. DESIGN: Um ensaio piloto controlado aleatoriamente. MÉTODOS: Os pacientes randomizados para o grupo I foram tratados com coil + cianoacrilato e os do grupo II apenas com cianoacrilato. O fluxo dentro da variz foi avaliado imediatamente após a sessão de tratamento e um mês após o tratamento inicial. Se a trombose foi confirmada, o acompanhamento adicional era realizado em 4 e 10 meses após o tratamento inicial. Todos os pacientes foram submetidos a uma tomografia computadorizada torácica após o procedimento. RESULTADOS: Um total de 32 pacientes, 16 em cada grupo, foram acompanhados por uma média de 9,9 meses (variação de 1-26 meses). Imediatamente após o procedimento, 6 (37,5%) pacientes do grupo I e 8 (50%) pacientes do grupo II apresentaram redução total do fluxo no vaso tratado (P=0,476). Após 30 dias, 11 (73,3%) pacientes do grupo I e 12 (75%) pacientes do grupo II apresentaram trombose da variz. Em ambos os grupos, a maioria dos pacientes necessitou de apenas uma única sessão para obliteração da variz (73,3% no grupo I versus 80% no grupo II). Embolia pulmonar assintomática ocorreu em 4 (25%) pacientes do grupo I e em 8 (50%) pacientes no grupo II (P=0,144). Nenhuma diferença significativa entre os grupos foi observada. CONCLUSÃO Apesar de não haver diferença estatística entre os dois grupos em relação à incidência de embolia neste estudo piloto, observou-se maior tendência de embolia no grupo tratado pela técnica convencional.


Subject(s)
Humans , Male , Female , Adult , Aged , Esophageal and Gastric Varices/therapy , Cyanoacrylates/administration & dosage , Pulmonary Embolism/etiology , Esophageal and Gastric Varices/diagnostic imaging , Injections, Intralesional/adverse effects , Injections, Intralesional/methods , Pilot Projects , Treatment Outcome , Hemostasis, Endoscopic/methods , Ethiodized Oil/administration & dosage , Endosonography/methods , Middle Aged
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