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1.
Rev. Ciênc. Méd. Biol. (Impr.) ; 20(1): 120-124, maio 5, 2021. fig, tab
Article in Portuguese | LILACS | ID: biblio-1355053

ABSTRACT

Introduction: dermatophytoses or "tineas" are characterized by being mycoses caused by fungi of the genera Epidermophyton, Trichophyton and Microsporum. These mycotic infections can present themselves as a form of lesions that affect the skin, hair and nails of individuals of both genders and all ages. Objective: to elucidate the epidemiological profile of dermatophytoses in patients examined by a private clinical analysis laboratory in João Pessoa-PB, between 2015 and 2019. Methodology: this is an epidemiological, analytical, retrospective and documentary study, in which data collection took place at the Clinical Pathology Laboratory ­ "HEMATO", located in João Pessoa ­ PB. Results: the profile of those affected was predominantly female (58.5%), 18 to 59 years old (38.4%), white (53.6%) and with lesions, mainly in skin glabrous (38.5%), feet (33.3%) and nails (12.8%). When relating the age group to the injury site, it was noticed that injuries on glabrous skin, feet and nails, were more frequent in individuals aged 18 to 59 years, while injuries to the scalp were mostly found in individuals younger than 18 years old. The most prevalent species were M. canis (31.9%) and T.rubrum (31.9%). When correlating the fungal species with the lesion site, it was noted that M. canis was the main agent responsible for lesions in glabrous skin, scalp and hands, while T. rubrum was predominantly observed in nails and T. mentagrophytes in feet. Conclusion: it is concluded that the data present in this research can promote the development of indicators and public policies for the population most susceptible to dermatophytosis.


Introdução: dermatofitoses ou tineas se caracterizam por serem micoses causadas por fungos dos gêneros Epidermophyton, Trichophyton e Microsporum. Essas infecções micóticas podem se apresentar na forma de lesões que acometem pele, pelo e unhas de indivíduos de ambos os gêneros e todas as idades. Objetivo: elucidar o perfil epidemiológico de dermatofitoses de pacientes atendidos por um laboratório privado de análises clínicas em João Pessoa-PB, entre 2015 a 2019. Metodologia: trata-se de um estudo epidemiológico, analítico, retrospectivo e documental, em que a coleta de dados ocorreu no Laboratório de Patologia Clínica ­ HEMATO, localizado em João Pessoa ­ PB. Resultados: o perfil de acometidos foi predominantemente de indivíduos do sexo feminino (58,5%), com 18 a 59 anos de idade (38,4%), brancos (53,6%) e com lesões, principalmente, em pele glabra (38,5%), pés (33,3%) e unhas (12,8%). Ao relacionar a faixa etária com o local da lesão, percebeu-se que lesões em pele glabra, pés e unhas, foram mais frequentes em indivíduos de 18 a 59 anos, enquanto que lesões no couro cabeludo foram majoritariamente encontradas em indivíduos menos de 18 anos. As espécies mais prevalentes foram M. canis (31,9%) e T. rubrum (31,9%). Ao correlacionar a espécie fúngica com o local da lesão, notou-se que M. canis foi o principal agente responsável por lesões em pele glabra, couro cabeludo e mãos, enquanto T. rubrum foi predominantemente observado em unhas e T. mentagrophytes em pés. Conclusão: os dados obtidos nesta pesquisa podem fomentar o desenvolvimento de indicadores e políticas públicas para a população mais susceptível às dermatofitoses.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Tinea , Arthrodermataceae , Fungi , Analytical Methods , Epidemiologic Methods , Retrospective Studies
2.
Gac. méd. Méx ; 157(2): 140-146, mar.-abr. 2021. tab
Article in Spanish | LILACS | ID: biblio-1279093

ABSTRACT

Resumen Introducción: La historia familiar de enfermedad tiroidea (HFET) como factor de riesgo para hipotiroidismo congénito (HC), en síndrome de Down (SD) aún no ha sido explorada. Objetivo: Determinar si la HFET está asociada a mayor riesgo de HC en neonatos con SD. Método: Estudio de casos y controles en 220 neonatos con SD. Se compararon las pruebas de función tiroidea (PFT) de 37 con SD e HFET (casos), frente a las PFT de 183 recién nacidos con SD sin HFET (grupo de referencia). Se realizó análisis de regresión logística multivariante y se calculó la razón de momios (RM) y sus respectivos intervalos de confianza del 95 % (IC 95 %). Resultados: Nueve casos HC (4.1 %). El HC mostró asociación con la HFET (RMa = 8.3, IC 95 %: 2.0-34.3), particularmente en los varones (RMa = 9.0, IC 95 %: 1.6-49.6). La ausencia de HFET tuvo una RM de protección para HC (RMa = 0.4, IC 95 %: 0.1-0.8). Conclusiones: La HFET puede es una estrategia fácil y accesible para identificar pacientes con SD con mayor riesgo de HC.


Abstract Introduction: Family history of thyroid disease (FHTD) as risk factor for congenital hypothyroidism (CH) in patients with Down syndrome (DS) has not yet been explored. Objective: To determine whether FHTD is associated with an increased risk for CH in DS. Method: Case-control study in 220 neonates with DS. Thyroid function tests of 37 infants with DS and FHTD (cases) were compared with those of 183 DS newborns without FHTD (reference group). Data were analyzed using multivariate logistic regression analysis and adjusted odds ratios (aORs) with their respective 95 % confidence intervals (CI) were calculated. Results: Nine newborns with DS in our sample had CH (4.1 %). FHTD showed an association with CH in neonates with DS (aOR = 8.3, 95 % CI: 2.0-34.3), particularly in males (aOR = 9.0, 95 % CI: 1.6-49.6). In contrast, newborns with DS without FHTD were less likely to suffer from CH (aOR = 0.4, 95 % CI: 0.1-0.8). Conclusions: FHTD detailed evaluation can be an easy and accessible strategy to identify those newborns with DS at higher risk for CH.


Subject(s)
Humans , Male , Female , Infant, Newborn , Thyroid Diseases/genetics , Family Health , Down Syndrome/complications , Congenital Hypothyroidism/etiology , Thyroid Function Tests/statistics & numerical data , Sex Factors , Epidemiologic Methods , Congenital Hypothyroidism/epidemiology
3.
Rev. cuba. med ; 60(1): e1382, tab
Article in Spanish | LILACS, CUMED | ID: biblio-1156560

ABSTRACT

Introducción: A partir de la aparición de la epidemia COVID-19 se conforma un equipo multidisciplinario en Santiago de Cuba con participación de varias instituciones y activado por el Consejo de defensa provincial. El análisis integrado epidemiológico, la gestión gubernamental y la respuesta social resultarían determinantes en el control de la enfermedad. Objetivos: Identificar posibles grupos de casos con COVID-19 en la provincia Santiago de Cuba y caracterizar su transmisión según variables epidemiológicas. Métodos: Se desarrolló un estudio ecológico, comparándose los clústeres de transmisión de COVID-19. Se resumieron variables de interés y se realizó análisis de redes sociales desde el punto de vista de las relaciones entre casos y contactos, así como análisis espacial. Resultados: Se identificaron cinco grupos espaciales de transmisión en los municipios, uno en Palma Soriano, uno en Contramaestre y tres en Santiago de Cuba. Los antecedentes patológicos personales (hipertensión y procesos respiratorios), el sexo femenino, los casos sintomáticos y el promedio de 22 a 27 contactos por cada confirmado fueron las variables más relevantes. Se identificó fuente de infección introducida en 51 por ciento (25/49). Además, se identificaron redes sociales complejas en la transmisión de la enfermedad. Conclusiones: La transmisión de COVID-19 en la provincia Santiago de Cuba mostró grupos de casos y contactos con redes sociales epidemiológicas características para cada municipio, así como el modo de transmisión de acuerdo a la fuente de infección, relaciones de familiaridad o cercanía social y la relación de distancia espacial entre contactos, aspectos que influyeron en las bajas tasas de incidencia de la enfermedad, con predominio en su forma sintomática, edades jóvenes y en mujeres(AU)


Introduction: From the onset of COVID-19 epidemic, a multidisciplinary team is formed in Santiago de Cuba with the participation of several institutions and activated by the Provincial Defense Council. Integrated epidemiological analysis, government management and social response would be decisive in controlling the disease. Objectives: To identify possible groups of COVID-19 cases in the Santiago de Cuba province and to describe the transmission according to epidemiological variables. Methods: An ecological study was carried out, comparing COVID-19 transmission clusters. Variables of interest were summarized and analysis of social contact networks was carried out from the point of view of the relationships between cases and contacts, as well as spatial analysis. Results: Five spatial transmission groups were identified in the municipalities, one in Palma Soriano, one in Contramaestre and three in Santiago de Cuba. The personal pathological antecedents (hypertension and respiratory processes), female sex, symptomatic cases and the average of 22 to 27 contacts for each confirmed were the most relevant variables. A source of introduced infection was identified in 51 percent (25/49). In addition, complex social networks were identified in the transmission of the disease. Conclusions: The transmission of COVID-19 in Santiago de Cuba province showed groups of cases and contacts with characteristic epidemiological social networks for each municipality, as well as the mode of transmission according to the source of infection, relationships of familiarity or social closeness and the relationship of spatial distance between contacts, which influenced on the low incidence rates of the disease, with predominance of symptomatic form, young ages and in women(AU)


Subject(s)
Humans , Cluster Analysis , Epidemiologic Methods , Coronavirus Infections/epidemiology , Social Networking , Cuba
4.
Rev. colomb. anestesiol ; 49(1): e501, Jan.-Mar. 2021. tab, graf
Article in English | LILACS, COLNAL | ID: biblio-1149799

ABSTRACT

Abstract Introduction Making decisions based on evidence has been a challenge for health professionals, given the need to have the tools and skills to carry out a critical appraisal of the evidence and assess the validity of the results. Systematic reviews of the literature (SRL) have been used widely to answer questions in the clinical field. Tools have been developed that support the appraisal of the quality of the studies. AMSTAR is one of these, validated and supported by reproducible evidence, which guides the methodological quality of the SRL. Objectives To show a historical, theoretical and practical guide for critical assessment of systematic reviews using AMSTAR to guide the argumental bases for their use according to the components of this methodological structure in health research, and to provide practical examples of how to apply this checklist. Methods We conducted a non-exhaustive review of literature in Pubmed and Cochrane Library using "AMSTAR" and "Systematic Reviews" as free terms without language or publication date limit; we also collected information from experts in the evaluation of the quality of the evidence. Conclusions AMSTAR is an instrument used, validated and supported by reproducible evidence for the evaluation of the internal validity of systematic reviews of the literature. It consists of 16 items that assess the overall methodological quality of a SRL. It is currently used indiscriminately and favorably, but it is not exempt from limitations and future updates based on new reproducibility and validation studies.


Resumen Introducción Tomar decisiones basadas en la evidencia ha sido un reto para profesionales de la salud; se requiere tener herramientas y habilidades para apreciar la evidencia críticamente y evaluar la validez de los resultados. Las revisiones sistemáticas de la literatura (RSL) han sido muy usadas para dar respuesta a preguntas del ámbito clínico. Se han desarrollado herramientas que apoyan la apreciación de la calidad de los estudios. El AMSTAR es una de estas, validada y soportada por evidencia reproducible que orienta la calidad metodológica de las RSL. Objetivos Mostrar un abordaje histórico, teórico y de guía práctica para la apreciación crítica de las revisiones sistemáticas con el AMSTAR, orientar las bases argumentales para su uso, según los componentes de esta estructura metodológica en investigación en salud, y proporcionar ejemplos prácticos sobre cómo aplicar esta lista de chequeo. Métodos Realizamos una revisión no exhaustiva de literatura en PubMed y The Cochrane Library con los términos libres "AMSTAR" y "revisiones sistemáticas'', sin límite de idioma o año de publicación; también, recolectamos información de expertos en evaluación de la calidad de la evidencia. Conclusiones El AMSTAR es un instrumento validado y soportado por evidencia reproducible para la evaluación de la validez interna de las revisiones sistemáticas de la literatura. Consiste en 16 ítems que evalúan de manera global la calidad metodológica de una RSL. Actualmente, se usa de manera indiscriminada y predilecta, pero no está exenta de limitaciones y futuras actualizaciones basadas en nuevos estudios de reproducibilidad y validación.


Subject(s)
Humans , Quality Assurance, Health Care , Epidemiologic Methods , Evidence-Based Practice , Review Literature as Topic , Meta-Analysis as Topic , Instruments for Management of Scientific Activity
5.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 13: 982-988, jan.-dez. 2021. tab
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1254995

ABSTRACT

Objetivo: verificar a prevalência de sintomas depressivos e associação com qualidade de vida em idosos institucionalizados. Métodos: estudo descritivo realizado com idosos de duas instituições de longa permanência do Paraná. Os dados foram coletados entre junho e setembro de 2018, mediante entrevista estruturada, utilizando o The World Health OrganizationQualityof Life (WHOQOL ­ bref) e a Escala de Depressão Geriátrica. Os dados foram analisados por meio de estatística descritiva e inferencial no software R. Resultados: a maioria dos idosos (62%) tinha algum grau de sintomas depressivos - leve ou severo. A qualidade de vida apresentou correlação com características sociodemográficas, condição de saúde, estilo de vida e presença de sintomas depressivos. Conclusão: a prevalência de sintomas depressivo na amostra estudada foi alta, o que indica a necessidade de maior atenção para a saúde mental de idosos residentes em instituições de longa permanência


Objective: to verify the prevalence of depressive symptoms and to evaluate the quality of life in institutionalized elderly. Methods: descriptive study carried out with elderly people from two long-term institutions in Paraná. Data were collected between June and September 2018, through a structured interview, using The World Health Organization Quality of Life (WHOQOL ­ bref ) and the Geriatric Depression Scale - GDS. The data were analyzed using descriptive and inferential statistics in the R software. Results: most of the elderly (62%) had some degree of depressive symptoms ­ mildor severe. Quality of life was correlated with sociodemographic characteristics, health condition, life style and presence of depressives ymptoms. Conclusion: the prevalence of depressive symptoms in the sample studied was high, which indicates the need for greater attention to the mental healt hof elderly people living in long-term institutions


Objetivo: verificar La prevalencia de sintomas depresivos y evaluar La calidad de vida em ancianos institucionalizados. Métodos: Estudio descriptivo realizado con personas mayores de dos instituciones de larga duración en Paraná. Los datos se recopilaron entre junio y septiembre de 2018, através de una entrevista estructurada, utilizando La Calidad de vida de La Organización Mundial de La Salud (WHOQOL) y la Escala de depresión geriátrica (GDS). Los datos se analizaron mediante estadísticas descriptivas e inferencial esen el software R. Resultados: La mayoría de losancianos (62%) tenían algún grado de sintomas depresivos, leves o graves. La calidad de vida se correlaciono com las características sociodemográficas, el estado de salud, el estilo de vida y la presencia de sintomas depresivos. Conclusión: la prevalencia de sintomas depresivos em La muestra estudiada fue alta, lo que indica La necesidad de una mayor atención a La salud mental de las personas mayores que viven em instituciones a largo plazo


Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Quality of Life , Aged/psychology , Adjustment Disorders/psychology , Mental Health , Depression/psychology , Health of Institutionalized Elderly , Epidemiologic Methods , Risk Factors
6.
Pesqui. vet. bras ; 41: e06749, 2021. tab, graf
Article in English | LILACS, VETINDEX | ID: biblio-1287512

ABSTRACT

Infectious laryngotracheitis (ILT), caused by an Alphaherpesvirus (Gallid herpesvirus-1; GaHV-1), has been noticed in the region of the Terras Altas da Mantiqueira, Minas Gerais. From 2010 to 2018, the "Serviço Veterinário Oficial" (SVO) of the "Instituto Mineiro Agropecuário" (IMA), implemented measures to prevent spread of the virus to other regions and control the disease in the area. Due to the close proximity and consequent epidemiological link among farms, the region was considered a unique epidemiological unit. To check the efficiency of the ILT control measures, we carried out: (1) a seroepidemiological survey, (2) questionnaires for evaluating biosecurity measures; and (3) an evaluation of the influence of farm population density on the occurrence of ILT. In 2016, 2017, and 2018, ILT was investigated using epidemiological and clinicopathological methods, along with GaHV-1 molecular detection. Serological survey was carried out on 24 farms in the quarantined region and on 13 farms from other regions of the state. In 2010 and 2018, questionnaires were applied to collect data and determine indicators of biosecurity practices in all farms of the quarantined area. The differences were then assessed (Wilcoxon's p<0.05). The results indicated positive serology throughout the region, although only on four farms (16.6%) the chickens have clinical signs, macroscopic and histological lesions of ILT. The prevalence of viral infection increased from 2016 (27%) to 2017 (50%) and was higher in farms with a high stock density (p=0.033). No disease, virus or antibodies were detected in the farms outside of the quarantined area. Although the biosecurity indicators had improved on all farms in the quarantined area (p<0.05), the virus was active and circulating in the region. The contingency measures have contained the outbreak, but biosecurity practices are paramount in the control of new outbreaks. Official control will be maintained in the region, including surveillance of new cases and biosecurity procedures to mitigate the risk of the virus reaching other regions.(AU)


Laringotraqueíte infecciosa (LTI), causada por um alfaherpesvírus (herpesvírus Gallid-1; GaHV-1), foi observada na região das Terras Altas da Mantiqueira, Minas Gerais. De 2010 a 2018, o Serviço Veterinário Oficial (SVO) do Instituto Mineiro Agropecuário (IMA) implementou medidas para impedir a disseminação do vírus para outras regiões do estado e controlar a doença na região interditada. Devido à proximidade e consequente vínculo epidemiológico entre as granjas, a região foi considerada uma unidade epidemiológica única. Para verificar a eficiência das medidas de controle de LTI, foram realizados: (1) pesquisa soroepidemiológica, (2) questionários para avaliar medidas de biosseguridade; e (3) avaliação da influência da densidade populacional da granja na ocorrência de LTI. Em 2016, 2017 e 2018, a LTI foi investigada usando métodos epidemiológicos e clínico-patológicos, com a detecção molecular de GaHV-1. O levantamento sorológico foi realizado em 24 granjas da região interditada e em 13 granjas de outras regiões do estado. Em 2010 e 2018, foram aplicados questionários para coletar dados e determinar indicadores de medidas de biosseguridade em todas as granjas da área interditada. As diferenças foram avaliadas (p<0,05 de Wilcoxon). Os resultados indicaram sorologia positiva em toda a região, embora apenas em quatro granjas (16,6%) as galinhas apresentaram sinais clínicos, lesões macroscópicas e histológicas da LTI. A prevalência de infecção viral aumentou de 2016 (27%) para 2017 (50%) e foi maior em fazendas com alta densidade de alojamento (p=0,033). Presença da doença, vírus ou anticorpos foram detectados nas granjas fora da área interditada. Embora os indicadores de biosseguridade tenham melhorado em todas as fazendas da área interditada (p<0,05), o vírus está ativo e circulava na região. As medidas de contingência contiveram o surto, mas as práticas de biosseguridade são fundamentais para o controle de novos surtos. O controle oficial será mantido na região, incluindo a vigilância de novos casos e procedimentos de biosseguridade para mitigar o risco de transmissão do vírus para outras regiões.(AU)


Subject(s)
Serology , Chickens , Epidemiologic Methods , Veterinarians , Surveillance , Indicators and Reagents
7.
Rev. colomb. anestesiol ; 48(3): 111-117, July-Sept. 2020. tab, graf
Article in English | LILACS, COLNAL | ID: biblio-1126292

ABSTRACT

Abstract Introduction: Total intravenous anesthesia (TIVA) and balanced anesthesia (BA) are the most commonly used anesthetic techniques. The differences are the variability of the depth of anesthesia between these techniques that might predict which one is safer for patients and presents a lower risk of intraoperative awakening. Objective: To determine whether a difference exists in the variability of depth of anesthesia obtained by response entropy (RE). Methods: A crossover clinical trial was conducted on 20 healthy patients receiving upper or lower limb ambulatory orthopedic surgery. Patients were randomly assigned to (a) target-controlled infusion of propofol using the Schnider model at a target concentration of 2.5 µg/mL for 15 minutes and a 10-minute washout, followed by sevoflurane administration at 0.8 minimal alveolar concentration (MAC) for the reminder of the surgery, or (b) the reverse sequence. Differences in the variability of the depth of anesthesia using RE were evaluated using paired t-test. Results: The treatment effect showed no significant difference in the average values of RE, during TIVA = 97.23 vs BA 97.04 (P = 0.39). Carry Over (-4.98 vs 4.08) and Period (100.3 vs 94.68) effects were not significantly different. Conclusion: The present study suggests that both anesthetic techniques are equivalent in terms of the stability of the depth of anesthesia. It is important to keep testing the determinants of the efficacy of different populations because the individual behaviors of patients might ultimately tip the scale.


Resumen Introducción: La anestesia total intravenosa (TIVA, por sus siglas en inglés) y la anestesia balanceada (AB) son las técnicas anestésicas más comúnmente utilizadas. La diferencia está en la variabilidad de la profundidad de la anestesia entre estas dos técnicas, lo cual pudiera predecir cuál es más segura para los pacientes y representar un menor riesgo de despertar intraoperatorio. Objetivo: Determinar si existe alguna diferencia en la variabilidad de la profundidad de la anestesia obtenida según los índices de entropía de respuesta (ER). Métodos: Se llevó a cabo un estudio clínico cruzado en 20 pacientes sanos que se sometieron a cirugía ortopédica ambulatoria de miembros superiores o inferiores. Los pacientes se asignaron aleatoriamente así: a) infusión controlada por objetivo (TCI, por sus siglas en inglés) de propofol, utilizando el modelo Schnider a una concentración objetivo de 2,5 µg/mL durante 15 min y un período de lavado de 10 minutos, seguido de la administración de sevoflurano a 0,8 de concentración alveolar mínima (CAM) durante el tiempo restante de la cirugía; o b) la secuencia inversa. Las diferencias en la variabilidad de la profundidad de la anestesia utilizando entropía de respuesta se evaluaron utilizando la prueba t pareada. Resultados: El efecto del tratamiento no mostró ninguna diferencia significativa en los valores promedio de entropía de respuesta (ER) durante TIVA = 97,23 vs. AB 97,04 (P = 0,39). Los efectos de arrastre (-4,98 vs. 4,08) y período (100,3 vs. 94,68) no fueron significativamente diferentes. Conclusiones: El presente estudio sugiere que ambas técnicas anestésicas son equivalentes en términos de estabilidad de la profundidad de la anestesia. Es importante continuar probando los factores determinantes de eficacia en las distintas poblaciones, ya que el comportamiento individual de cada paciente pudiera finalmente inclinar la balanza.


Subject(s)
Humans , Male , Female , Adult , Entropy , Intraoperative Awareness , Balanced Anesthesia , Anesthesia, Intravenous , Propofol , Epidemiologic Methods , Sevoflurane
8.
Homeopatia Méx ; 89(721): 30-39, abr.-jun. 2020.
Article in Spanish | MTYCI, LILACS, HomeoIndex, MTYCI | ID: biblio-1359468

ABSTRACT

Pandemia de consecuencias sanitarias, sociales y económicas incalculables, la enfermedad COVID-19 parece haber llegado para quedarse mucho tiempo entre nosotros, y cuando decimos "nosotros" nos referimos a los 7,700 millones de habitantes del planeta. (au)


Subject(s)
Homeopathic Therapeutics , Epidemiologic Methods , Pandemics
9.
Rev. Assoc. Med. Bras. (1992) ; 66(3): 275-283, Mar. 2020. tab, graf
Article in English | SES-SP, LILACS, SES-SP | ID: biblio-1136210

ABSTRACT

SUMMARY Malignant liver tumors are the fourth leading cause of cancer death worldwide. Hepatocellular carcinoma (HCC) accounts for 75-85% of these. Most patients are diagnosed at incurable stages. Palliative care is the appropriate treatment course in these circumstances (chemoembolization and sorafenib). There are few national studies on sorafenib. The objective is to evaluate survival predictors of HCC patients treated with sorafenib and evaluate the compliance of its indication in relation to BCLC recommendations. METHODS A total of 88 patients with an indication of sorafenib from 2010 to 2017 at the ISCMSP were retrospectively analyzed. Univariate and multivariate analyzes were performed in the search for predictors of survival. RESULTS The mean age was 61.2 years, 70.5% were men, most were classified as Child-Pugh A (69.3%), and BCLC C (94.3%). Cirrhosis was present in 84.6% and portal hypertension in 55.7%. Hepatitis C virus was the most common etiology (40.9%). Sixty-nine (78.4%) patients received the medication, with the average duration of treatment being 9.7 months. The mean overall survival was 16.8 months. Significant differences were observed in the multivariate analysis: ECOG PS (p = 0.024): Child-Pugh (p = 0.013), time of medication use (p <0.001), clinical worsening (p = 0.031) and portal thrombosis (p = 0.010). CONCLUSION Absence of portal thrombosis, Child-Pugh A, longer time of medication use, ECOG PS 0, and absence of suspension due to clinical worsening were predictors of better overall survival in the study. The drug's indication complies with BCLC guidelines in 94% of patients.


RESUMO Tumores malignos do fígado são a quarta maior causa de morte por câncer, sendo que o carcinoma hepatocelular (CHC) corresponde a 85-90% desses casos. A maioria dos doentes apresenta-se, ao diagnóstico, sem possibilidade de tratamento curativo, restando apenas as opções paliativas (quimioembolização e sorafenibe). Há poucos estudos nacionais acerca do sorafenibe. OBJETIVO Avaliar fatores preditivos de sobrevida em pacientes com CHC que tiveram indicação de tratamento com sorafenibe na Irmandade da Santa Casa de Misericórdia de São Paulo (ISCMSP) e avaliação da conformidade da indicação da medicação em relação às recomendações do BCLC. MÉTODOS Foram analisados retrospectivamente os dados de 88 pacientes que tiveram indicação de tratamento com sorafenibe no período de 2010 a 2017 na ISCMSP. Análises univariada e multivariada foram realizadas na busca de preditores de sobrevida global nos pacientes que receberam a medicação. RESULTADOS Idade média de 61,2 anos, sendo 70,5% homens. A maioria (69,3%) foi classificada como Child Pugh A e BCLC C (94,3%). A cirrose esteve presente em 84,6% e a hipertensão portal em 55,7% desses. O vírus da hepatite C foi a etiologia mais comum (40,9%) do CHC. Sessenta e nove (78,4%) pacientes receberam a medicação, sendo o tempo médio de duração do tratamento 9,7 meses e a sobrevida global média, 16,8 meses. Diferenças significativas foram observadas na análise multivariada: Ecog PS (p=0,024), CP (p=0,013), tempo de uso de medicação (p<0,001), suspensão por piora clínica (p=0,031) e trombose portal (p=0,010). CONCLUSÃO Ausência de trombose portal, Child Pugh A, Ecog PS 0, tempo maior de uso de medicação e ausência de suspensão por piora clínica foram fatores preditores de melhor sobrevida global e a indicação da medicação esteve em conformidade com as orientações do BCLC em 94% dos pacientes.


Subject(s)
Humans , Male , Female , Carcinoma, Hepatocellular/drug therapy , Sorafenib/therapeutic use , Liver Neoplasms/drug therapy , Antineoplastic Agents/therapeutic use , Palliative Care , Epidemiologic Methods , Treatment Outcome , Carcinoma, Hepatocellular/mortality , Carcinoma, Hepatocellular/pathology , Liver Neoplasms/mortality , Liver Neoplasms/pathology , Middle Aged , Neoplasm Staging
10.
Article in English | LILACS, BBO | ID: biblio-1135501

ABSTRACT

Abstract Objective: To identify the need for restorative treatment in 12-year-old Brazilian schoolchildren with dental trauma and its association with clinical and socioeconomic factors. Material and Methods: A cross-sectional population-based study was carried out with sample composed of 588 12-year-old students from the city of Diamantina, Minas Gerais, Brazil. Data were collected from August to November 2016 through clinical examination, adopting the Andreasen classification and semi-structured questionnaire to verify the etiology and location of the accident that resulted in dental trauma. Statistical analysis included the frequency distribution and bi and multivariate analysis, with 5% significance level. Results: The presence of 219 traumatized teeth in 176 students was observed (29.9%). The main lesion was enamel fracture (41.4%), followed by enamel and dentin fracture (39.4%). The presence of restorative treatment was observed only in 11.5% of students. Fall (43.5%) was the most frequent etiology, followed by accidents on the streets (35.8%). Need for treatment was present in 53.4% of adolescents. Statistically significant association between males (p=0.010), severe overjet (p<0.0001) and inadequate lip protection (p<0.0001) and presence of dental trauma was observed. Maternal schooling over 8 years of study was statistically associated with need for restorative treatment (OR = 2.047; CI: 1.099-3.813; p=0.023). Conclusion: Prevalence of dental trauma, need for restorative treatment and number of adolescents with no access to restorative treatment in this study were high, point out that the health system is unable to satisfactorily prevent dental trauma and absorb all dental treatment demand resulting from dental trauma.


Subject(s)
Students , Brazil/epidemiology , Epidemiologic Methods , Tooth Injuries/etiology , Dental Enamel , Socioeconomic Factors , Oral Health/education , Prevalence , Cross-Sectional Studies , Multivariate Analysis , Surveys and Questionnaires
11.
Article in English | LILACS, BBO | ID: biblio-1056869

ABSTRACT

Abstract Objective: To evaluate the dental caries experience and clinical consequences of untreated dental caries (UDC) among primary school children of Al Jouf region, Saudi Arabia and to determine the correlation between dental caries experience and clinical consequences of UDC. Material and Methods: A 250 primary school children 6-7 years were recruited using systematic random sampling. The prevalence of dental caries in deciduous dentition was assessed by following WHO criteria using the dmft index and the clinical consequence of UDC was assessed with the pufa index. The pufa score was calculated cumulatively following the pufa diagnostic criteria. The Student's t-test was used to equate the mean dmft and pufa scores between boys and girls. The correlation between the dmft and the pufa scores was evaluated using Pearson's correlation coefficient (r), and the p-value was set at 0.05 for statistical significance. Results: Out of which 154 (61.60%) boys and 94 (37.60%) were girls. The mean (SD) values of dmft for boys reported to be 5.37 (± 3.31) and for girls 6.35 (± 3.27), which was statistically significant with gender (p<0.001). Statistically, significant mean values of pufa were 1.20 (± 1.37) in boys and 1.71 (± 1.58) in girls, respectively was observed (p<0.001). The Pearson correlation between dmft and pufa values showed a highly significant positive correlation among dmft and pufa values (r= 0.635, p<0.001). Conclusion: The present study revealed that high caries prevalence and experience of the clinical consequences of UDC in the primary dentition, and there was a strong positive correlation between dmft and pufa score values.


Subject(s)
Humans , Male , Female , Child , Child , DMF Index , Epidemiologic Methods , Dental Caries/prevention & control , Saudi Arabia/epidemiology , Cross-Sectional Studies/methods , Data Interpretation, Statistical
12.
Rev. Soc. Bras. Med. Trop ; 53: e20190193, 2020. tab
Article in English | LILACS | ID: biblio-1057301

ABSTRACT

Abstract INTRODUCTION: Prevalence of human immunodeficiency virus among adolescents is increasing. This study aimed to analyze this current situation in Rio de Janeiro City. METHODS: This was a retrospective longitudinal study using secondary data from the National System of Notifiable Diseases database of cases in adolescents aged 13-19 years. RESULTS: There were 885 acquired immunodeficiency syndrome cases from 1978 to 2017 and 445 human immunodeficiency virus new cases from 2014 to 2017. Over time, sexually transmitted human immunodeficiency virus/acquired immunodeficiency syndrome cases increase. CONCLUSIONS: Human immunodeficiency virus/acquired immunodeficiency syndrome epidemic in adolescents requires novel prevention policies.


Subject(s)
Humans , Male , Female , Adolescent , Young Adult , Acquired Immunodeficiency Syndrome/epidemiology , Epidemics , Urban Population , Brazil/epidemiology , Epidemiologic Methods
13.
Rev. Soc. Bras. Med. Trop ; 53: e20190377, 2020. tab, graf
Article in English | LILACS | ID: biblio-1092223

ABSTRACT

Abstract INTRODUCTION: Snakebites represent a serious global public health problem, especially in tropical countries. In Brazil, the incidence of snakebites ranges from 19 to 22 thousand cases per 100000 persons annually. The state of Rondônia, in particular, has had an increasing incidence of snakebites. METHODS: A retrospective cross-sectional study on snakebites was conducted from January 2007 to December 2018. Brazil's Information System for Notifiable Diseases was queried for all snakebites reported in Porto Velho, Ariquemes, Cacoal, and Vilhena. Data on land surface temperatures during the day and night, precipitation, and humidity were obtained using the Google Earth Engine. A Bayesian time series model was constructed to describe the pattern of snakebites and their relationship with climate data. RESULTS: In total, 6326 snakebites were reported in Rondônia. Accidents were commonly caused by Bothrops sp. (n=2171, 81.80%). Snakebites most frequently occurred in rural areas (n=2271, 85.5%). Men, with a median age of 34 years (n=2101, 79.1%), were the most frequent bitten. Moderate clinical manifestation was the most common outcome of an accident (n=1101, 41.50%). There were clear seasonal patterns with respect to rainfall, humidity, and temperature. Rainfall and land surface temperature during the day or night did not increase the risk of snakebites in any city; however, changes in humidity increased the risk of snakebites in all cities. CONCLUSION: This study identified the population exposed to snakes and the influence of anthropic and climatic factors on the incidence of snakebites. According to climate data, changes in humidity increased the risk of snakebites.


Subject(s)
Humans , Animals , Adult , Snake Bites/epidemiology , Seasons , Brazil/epidemiology , Epidemiologic Methods , Humidity
14.
Rev. bras. epidemiol ; 23: e200052, 2020. tab
Article in Portuguese | LILACS | ID: biblio-1101577

ABSTRACT

RESUMO: Objetivo: Analisar o comportamento da prevalência de hipertensão arterial no município de São Paulo e seus fatores associados. Métodos: O presente trabalho utilizou os dados do Inquérito de Saúde no Município de São Paulo (ISA Capital), estudo transversal de base populacional executado no município de São Paulo. Foram utilizados dados de 1.667 e de 3.184 indivíduos em 2003 e 2015, respectivamente, com idade de 20 anos e mais. Fizeram-se análises descritivas das prevalências de hipertensão arterial com respectivos intervalos de 95% de confiança. Análises simples e múltiplas foram realizadas para analisar possíveis associações com as variáveis socioeconômicas, demográficas e de estilo de vida por meio de regressão de Poisson. Resultados: A prevalência de hipertensão arterial passou de 17,2% em 2003 para 23,2% em 2015. Os fatores associados à hipertensão foram: sexo feminino; idade (60 anos e mais); situação conjugal (casados, separados e viúvos); ter religião; baixa escolaridade; ter nascido no estado de São Paulo (exceto capital); estado nutricional (baixo peso, sobrepeso e obesidade); e ex-fumantes. Conclusão: A prevalência de hipertensão autorreferida aumentou significativamente no período estudado em São Paulo. Considerando o impacto dessa doença na sociedade, conhecendo sua atual prevalência e identificando seus principais fatores associados, evidencia-se a necessidade de intensificar atividades que contribuam para a prevenção desse agravo, atenuando os danos aos indivíduos e gastos públicos.


ABSTRACT: Objective: To analyze the behavior of the prevalence of hypertension in the city of São Paulo and its associated factors. Methods: The present study used data from the Health Survey in the Municipality of São Paulo (ISA Capital), a population-based cross-sectional study conducted in São Paulo. Data from 1,667 and 3,184 individuals were analyzed in 2003 and 2015, respectively, aged 20 years and over. Descriptive analyzes of the prevalence of hypertension were performed with 95% confidence intervals. Simple and multiple analyzes were performed to analyze the possible associations with socioeconomic, demographic and lifestyle variables by Poisson regression. Results: The prevalence of hypertension increased from 17.2% in 2003 to 23.2% in 2015. The associated variables with hypertension were: gender (females); age (60 years old and over); marital status (married, separated and widowed); having a religion; low education level; being born in the state of São Paulo (except capital); nutritional status (low weight, overweight and obesity); former smokers. Conclusion: The prevalence of self-reported hypertension increased significantly in the study period. Considering this disease's impact on society, knowing its current prevalence and identifying its main associated factors, the need to intensify the efforts to prevent it disease is evident in order to mitigate damage to individuals and impact on public expenditure.


Subject(s)
Humans , Male , Female , Adult , Aged , Young Adult , Hypertension/epidemiology , Socioeconomic Factors , Brazil/epidemiology , Sex Factors , Nutritional Status , Epidemiologic Methods , Age Factors , Hypertension/diagnosis , Middle Aged
15.
Buenos Aires; s.n; 2020. 20 p.
Non-conventional in Spanish | LILACS, InstitutionalDB, BINACIS, UNISALUD | ID: biblio-1353778

ABSTRACT

El presente trabajo tiene como objetivo describir las actividades realizadas por el equipo de psicopedagogía, durante la pandemia COVID-19. A mediados del mes de marzo del 2020, se declaró el Aislamiento Social Preventivo y Obligatorio (ASPO) en la Ciudad Autónoma de Buenos Aires y como consecuencia, las actividades que se realizaban diariamente en el hospital se vieron modificadas y/o suspendidas. Esto llevó a repensar y reestructurar tareas como la atención presencial, las rotaciones programáticas, los dispositivos interdisciplinarios, entre otras. Asimismo, el equipo comenzó a realizar nuevas actividades en colaboración con otros profesionales. Se presenta brevemente el hospital General de Agudos Dr. José María Ramos Mejía, el equipo de Psicopedagogía Estratégico Interaccional y el Área Programática en el cual el equipo está inserto, con el objetivo de poder comprender su nuevo rol a partir de la pandemia, y se detallan las actividades que fue realizando el mismo, desde mediados de marzo. (AU)


Subject(s)
Social Isolation , Epidemiologic Methods , Pandemics , Epidemiological Monitoring , COVID-19 , Hospitals, General , Inservice Training , Internship and Residency/methods , Internship and Residency/trends
16.
Braz. j. infect. dis ; 23(6): 464-467, Nov.-Dec. 2019. tab, graf
Article in English | LILACS | ID: biblio-1089308

ABSTRACT

ABSTRACT Background: Effective antiretroviral therapy (ART) has increased life expectancy for HIV patients to levels close to that observed for general population. Comorbidities are also increasing, due to ageing of such population. Erectile dysfunction (ED) has been a frequent finding in men living with HIV. Objectives: The goals of the present study were to define the prevalence of ED and associated factors in HIV-infected men, in a referral center of Salvador city, Brazil. Methods: HIV-infected men ≥18 years of age, receiving care at the AIDS Clinics of Complexo Hospitalar Professor Edgard Santos (C-HUPES), Universidade Federal da Bahia were consecutively included in the study until the estimated sample size (N = 134) was reached. Patients filled a structured questionnaire on clinical-epidemiological characteristics, as well as the International Index on Erectile Function to assess ED. Results: Most (55%) were black and single (79%), mean age 44.8 years. ED was detected in 29 (21.6%) patients; 86% of ED cases were classified as severe. The only factors associated with ED were low income (p = 0.02) and unemployment (p = 0.01). No association was found between ED and frequency of comorbidities, age, or ART used by patients. Conclusion: In a referral center in Salvador city, socio-economic problems were the main factors associated with ED. Psychological impact of poor social conditions should be routinely assessed in patients with ED to implement preventive measures for ED.


Subject(s)
Humans , Male , Adolescent , Adult , Young Adult , Comorbidity , HIV Infections/complications , Erectile Dysfunction/etiology , Socioeconomic Factors , Brazil/epidemiology , HIV Infections/drug therapy , HIV Infections/epidemiology , Epidemiologic Methods , Anti-Retroviral Agents/therapeutic use , Erectile Dysfunction/epidemiology
17.
J. pediatr. (Rio J.) ; 95(6): 657-666, Nov.-Dec. 2019. tab
Article in English | LILACS | ID: biblio-1056655

ABSTRACT

ABSTRACT Objective: To investigate the occurrence of infectious morbidities according to day care attendance during the first year of life. Methods: This was a cross-sectional analysis of data from the 12-month follow-up of a medium-sized city birth cohort from children born in 2015, in the Southern Brazil. Main exposure variables were day care attendance from 0 to 11 months of age, type of day care center (public or private), and age at entering day care. Health outcomes were classified as follows: "non-specific respiratory symptoms," "upper respiratory tract infection," "lower respiratory tract infection," "flu/cold," "diarrhea," or "no health problem," considering the two weeks prior to the interview administered at 12 months of life. Associations were assessed using Poisson regression adjusted by demographic, behavioral, and socioeconomic variables. Results: The sample included 4018 children. Day care attendance was associated with all classifications of health outcomes mentioned above, except for flu/cold. These were stronger among children who entered day care at an age closer to the outcome time-point. An example are the results for lower respiratory tract infection and diarrhea, with adjusted prevalence ratios of 2.79 (95% CI: 1.67-4.64) and 2.04 (95% CI: 1.48-2.82), respectively, for those who entered day care after 8 months of age when compared with those who never attended day care. Conclusions: The present study consistently demonstrated the association between day care attendance and higher occurrence of infectious morbidities and symptoms at 12 months of life. Hence, measures to prevent infectious diseases should give special attention to children attending day care centers.


RESUMO Objetivo: Investigar a ocorrência de morbidades infecciosas de acordo com a frequência em creches durante o primeiro ano de vida. Métodos: Esta foi uma análise transversal dos dados de uma coorte de nascimento, em uma cidade de tamanho médio, na visita aos 12 meses de idade de crianças nascidas em 2015 no Sul do Brasil. As principais variáveis de exposição foram frequência em creches de zero aos 11 meses de idade, tipo de creche (pública ou particular) e idade ao entrar na creche. Os resultados de saúde foram classificados como: "sintomas respiratórios não específicos", "infecção do trato respiratório superior", "infecção do trato respiratório inferior", "gripe/resfriado", "diarreia" ou "nenhum problema de saúde", considerando as duas semanas anteriores à entrevista feita aos 12 meses de vida da criança. As associações foram avaliadas com a regressão de Poisson ajustada pelas variáveis demográficas, comportamentais e socioeconômicas. Resultados: A amostra incluiu 4.018 crianças. O ato de frequentar creches foi associado a todas as classificações de resultados de saúde mencionados, exceto gripe/resfriado. Esses resultados foram mais fortes entre as crianças que começaram a frequentar creches em uma idade mais próxima ao ponto de tempo do resultado. Um exemplo são os resultados para infecção do trato respiratório inferior e diarreia, índice de prevalência ajustado de 2,79 (IC de 95%: 1,67-4,64) e 2,04 (IC de 95%: 1,48-2,82), respectivamente, naqueles que ingressaram nas creches após os oito meses de idade, em comparação com aqueles que nunca frequentaram creche. Conclusões: O presente estudo mostra sistematicamente a associação entre a frequência em creches e a maior ocorrência de morbidades infecciosas e sintomas aos 12 meses de vida da criança. Assim, deve-se dar atenção especial às medidas para prevenir as doenças infecciosas em crianças que frequentes creches.


Subject(s)
Humans , Male , Female , Adult , Respiratory Tract Infections/epidemiology , Child Day Care Centers/statistics & numerical data , Diarrhea, Infantile/epidemiology , Respiratory Tract Infections/prevention & control , Respiratory Tract Infections/transmission , Socioeconomic Factors , Epidemiologic Methods , Public Sector , Private Sector , Disease Transmission, Infectious , Qualitative Research , Diarrhea, Infantile/prevention & control
18.
Prensa méd. argent ; 105(9 especial): 628-633, oct 2019.
Article in English | LILACS, BINACIS | ID: biblio-1046836

ABSTRACT

The article reveals the features of the study and development of the tempo-rhythmic speech components of children with disabilities as exemplified by preschool children with a stutter. The article describes the course and methods of an ascertaining experiment to identify the initial state of the tempo-rhythmic speech components of children with stuttering. Games and tasks, with the help which it is possible to determine the state of the tempo and rhythm of children's speech, are offered and the obtained results are described. The stages of correctional work with children on the development of the tempo-rhythmic speech components of children with stuttering are given.


Subject(s)
Humans , Child, Preschool , Child , Speech , Speech Therapy/methods , Stuttering/etiology , Time , Epidemiologic Methods , Disabled Children/rehabilitation , Games, Experimental
19.
Educ. med. super ; 33(3): e1574, jul.-set. 2019. []
Article in Spanish | LILACS, CUMED | ID: biblio-1089926

ABSTRACT

Introducción: El proceso docente educativo que se desarrolla desde la educación en el trabajo debe sustentarse en una concepción didáctica de actualidad y pertinencia, en función de preparar a un individuo capaz de enfrentar nuevas situaciones y problemas mediante los métodos científicos. Objetivo: Caracterizar los dos momentos didácticos para el desarrollo de habilidades investigativas desde la educación en el trabajo. Métodos: Se realizó una investigación cualitativa en la carrera de Medicina en el ciclo clínico en la Filial de Ciencias Médicas "Lidia Doce Sánchez" de Sagua la Grande en el período 2014-2016. La población de estudio estuvo constituida por 160 estudiantes desde 3ro hasta 5to años de Medicina (ciclo clínico). La muestra fue seleccionada por un muestreo estratificado guiado por propósito y quedó finalmente constituida por 44 estudiantes. Además, participaron estudiantes de 6to año mediante un muestreo aleatorio simple, los profesores y tutores fueron seleccionados a través de un muestreo no probabilístico intencional, y los directivos y metodólogos de la carrera fueron seleccionados en su totalidad. La recogida de la información se realizó a través de diferentes técnicas: análisis de documento, encuesta a los profesores, encuesta a estudiantes, observación a las actividades de educación en el trabajo y entrevista a directivos y metodólogos. Resultados: El proceso docente educativo contribuyó al desarrollo de las habilidades investigativas de los estudiantes. Este debió ejecutarse en dos momentos didácticos fundamentales: la preparación de la ejecución y la ejecución del proceso, en los cuales se concibió la tarea investigativa y fueron diseñados teniendo en cuenta los problemas de salud que afectan al individuo, la familia, la comunidad y el medio ambiente. Conclusiones: Los dos momentos didácticos para la educación en el trabajo contribuyeron al desarrollo de las habilidades investigativas, al favorecer la adquisición de los modos de actuación profesional relacionados con los métodos clínico y epidemiológico(AU)


Introduction: The teaching-learning process carried out via on-the-job training should be based on current, relevant didactic principles, so that professionals are trained who can face up to new situations and problems applying scientific methods. Objective: Characterize the two didactic moments suitable for developing research skills via on-the-job training. Methods: A qualitative study was conducted of the Medicine major during its clinical cycle at Lidia Doce Sánchez Medical Sciences Branch School in Sagua la Grande in the period 2014-2016. The study population was 160 third-to-fifth-year medical students (clinical cycle). The sample was selected by purposive stratified sampling and was finally made up of 44 students. Additionally, sixth-year students were selected by simple random sampling. Teachers and tutors were chosen by purposive non-probability sampling. All faculty managers and methodologists went through the selection process. Data collection was based on document analysis, teacher surveys, student surveys, observation of on-the-job activities, and interviews with managers and methodologists. Results: The teaching-learning process conducted via on-the-job training in the major of Medicine in the various primary and secondary training environments, contributed to develop students' research skills. The process should be performed at two main didactic moments: preparation for conduct and process conduct. Research as the cornerstone of the teaching-learning process was conceived of as taking place at these two didactic moments, which were designed bearing in mind the health problems affecting the individual, the family, the community and the environment. Conclusions: The two didactic moments occurring during on-the-job training contributed to develop research skills, fostering the acquisition of professional behavior modes related to the clinical and epidemiological methods(AU)


Subject(s)
Humans , Schools , Students, Medical , Epidemiologic Methods , Qualitative Research
20.
Rev. bras. cir. cardiovasc ; 34(4): 396-405, July-Aug. 2019. tab, graf
Article in English | LILACS | ID: biblio-1020497

ABSTRACT

Abstract Objective: To evaluate whether there is any difference on the results of patients treated with coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) in the setting of ischemic heart failure (HF). Methods: Databases (MEDLINE, Embase, Cochrane Controlled Trials Register [CENTRAL/CCTR], ClinicalTrials.gov, Scientific Electronic Library Online [SciELO], Literatura Latino-americana e do Caribe em Ciências da Saúde [LILACS], and Google Scholar) were searched for studies published until February 2019. Main outcomes of interest were mortality, myocardial infarction, repeat revascularization, and stroke. Results: The search yielded 5,775 studies for inclusion. Of these, 20 articles were analyzed, and their data were extracted. The total number of patients included was 54,173, and those underwent CABG (N=29,075) or PCI (N=25098). The hazard ratios (HRs) for mortality (HR 0.763; 95% confidence interval [CI] 0.678-0.859; P<0.001), myocardial infarction (HR 0.481; 95% CI 0.365-0.633; P<0.001), and repeat revascularization (HR 0.321; 95% CI 0.241-0.428; P<0.001) were lower in the CABG group than in the PCI group. The HR for stroke showed no statistically significant difference between the groups (random effect model: HR 0.879; 95% CI 0.625-1.237; P=0.459). Conclusion: This meta-analysis found that CABG surgery remains the best option for patients with ischemic HF, without increase in the risk of stroke.


Subject(s)
Humans , Male , Female , Aged , Coronary Artery Bypass/mortality , Myocardial Ischemia/surgery , Stroke/etiology , Percutaneous Coronary Intervention/mortality , Heart Failure/surgery , Postoperative Complications/etiology , Postoperative Complications/mortality , Brazil/epidemiology , Review Literature as Topic , Randomized Controlled Trials as Topic , Meta-Analysis as Topic , Coronary Artery Bypass/adverse effects , Epidemiologic Methods , Multicenter Studies as Topic , Treatment Outcome , Practice Guidelines as Topic , Myocardial Ischemia/mortality , Evidence-Based Medicine , Stroke/mortality , Percutaneous Coronary Intervention/adverse effects
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