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3.
Int. braz. j. urol ; 48(2): 212-219, March-Apr. 2022. graf
Article in English | LILACS | ID: biblio-1364948

ABSTRACT

ABSTRACT Despite the neuroanatomy knowledge of the prostate described initially in the 1980's and the robotic surgery advantages in terms of operative view magnification, potency outcomes following robotic-assisted radical prostatectomy still challenge surgeons and patients due to its multifactorial etiology. Recent studies performed in our center have described that, in addition to the surgical technique, some important factors are associated with erectile dysfunction (ED) following robotic-assisted radical prostatectomy (RARP). These include preoperative Sexual Health Inventory for Men (SHIM) score, age, preoperative Gleason score, and Charlson Comorbidity Index (CCI). After performing 15,000 cases, in this article we described our current Robotic-assisted Radical Prostatectomy technique with details and considerations regarding the optimal approach to neurovascular bundle preservation.


Subject(s)
Humans , Male , Prostatic Neoplasms/surgery , Prostatic Neoplasms/complications , Robotic Surgical Procedures/methods , Erectile Dysfunction/etiology , Erectile Dysfunction/prevention & control , Prostate/surgery , Prostatectomy/adverse effects , Prostatectomy/methods , Treatment Outcome
5.
urol. colomb. (Bogotá. En línea) ; 31(1): 43-44, 15/03/2022.
Article in Spanish | LILACS, COLNAL | ID: biblio-1368849

ABSTRACT

Con respecto al estudio de Espitia-De La Hoz[1] publicado en su prestigiosa revista, quisiéramos expresar algunas particularidades importantes. Esperando que dichos argumentos ayuden a mejorar la lectura crítica de artículos científicos. Para poner en contexto y como primer punto, este estudio se plantea como intervención el uso del tadalafilo a una dosis de 2,5 mg diarios durante 12 semanas en mujeres. Llama la atención que no se especifican los motivos por los cuales se establece esta dosis. En Colombia se encuentran disponibles las presentaciones de 5 mg, 10 mg y 20 mg para hombres con disfunción erectil, hiperplasia prostática benigna o su combinación.[2] Además, los registros sanitarios de Instituto Nacional de Vigilância de Medicamentos e Alimentos (INVIMA) no dan registro de esta presentación ni el uso en mujeres.[3] Se deja como mensaje a la comunidad científica, que el tadalafilo es un comprimido recubierto, sin ranuras, por lo tanto no debe dividirse de ninguna forma.[4] [5] Adicionalmente, su uso en mujeres sería off label y solo debería realizarse en el contexto de un estudio de investigación.


With respect to the study by Espitia-De La Hoz[1] published in your prestigious journal, we would like to express some important particularities. We hope that these arguments will help to improve the critical reading of scientific articles. To put in context and as a first point, this study proposes as an intervention the use of tadalafil at a dose of 2.5 mg daily for 12 weeks in women. It is noteworthy that the reasons for establishing this dose are not specified. In Colombia, 5 mg, 10 mg and 20 mg presentations are available for men with erectile dysfunction, benign prostatic hyperplasia or their combination.[2] Furthermore, the health records of the Instituto Nacional de Vigilância de Medicamentos e Alimentos (INVIMA) give no record of this presentation or its use in women. [3] It is left as a message to the scientific community that tadalafil is a coated tablet, without grooves, therefore it should not be divided in any way. 4] [5] In addition, its use in women would be off label and should only be performed in the context of a research study.


Subject(s)
Humans , Male , Prostatic Hyperplasia , Tadalafil , Erectile Dysfunction , Pharmaceutical Preparations , Surveillance in Disasters
6.
Asian Journal of Andrology ; (6): 294-298, 2022.
Article in English | WPRIM | ID: wpr-928557

ABSTRACT

General recommendations regarding surgical techniques are not always appropriate for all Peyronie's disease (PD) patients. Therefore, the purpose of this study was to investigate the effects of plication procedures in PD patients with severe penile curvature and the effects of early surgical correction in patients who no longer have progressive deformities. The clinical data from 72 patients who underwent plication procedures were analyzed in this study. Patients were divided into Groups A and B according to the curvature severity (≤60° or >60°) and Groups 1 and 2 according to the duration of disease stabilization (≥3 months or <3 months). At the 1-year follow-up, 90.0% (36/40) and 90.6% (29/32) patients reported complete penile straightening, and 60.0% (24/40) and 100.0% (32/32) patients reported penile shortening in Groups A and B, respectively. No curvature recurrence occurred in any patient, and no significant differences were observed in postoperative International Index of Erectile Function-Erectile Function domain (IIEF-EF), erectile pain, sensitivity, or suture knots on the penis whether such outcomes were grouped according to the curvature severity or the duration of stabilization. However, the duration from symptom onset to surgical management in Group 1 was significantly longer than that in Group 2 (mean ± standard deviation [s.d.]: 20.9 ± 2.0 months and 14.3 ± 1.2 months, respectively, P < 0.001). The present study showed that the plication procedures seemed to be an effective choice for the surgical treatment of PD patients with severe penile curvature. In addition, the early surgical treatment seemed to benefit those patients who already had no erectile pain and no longer exhibited progressive deformity.


Subject(s)
Erectile Dysfunction/surgery , Humans , Male , Patient Satisfaction , Pelvic Pain , Penile Induration/surgery , Penis/surgery , Retrospective Studies , Treatment Outcome
7.
Asian Journal of Andrology ; (6): 167-170, 2022.
Article in English | WPRIM | ID: wpr-928518

ABSTRACT

Penile prosthetic implantation represents a cornerstone for patients with organic erectile dysfunction (ED) that is refractory, unsatisfactory, or contra-indicated for other approved medical or mechanical options. In this study, we introduce the "Ghattas technique," wherein we constructed a polypropylene mesh sheath that surrounds and is fixed to a 13-mm malleable prosthesis cylinder, which can increase the cylinder diameter for cases that need a larger prosthesis. All patients underwent preoperative evaluation and completed the five-item International Index of Erectile Function questionnaire (IIEF-5). Postoperative outcomes were evaluated by IIEF-5 and Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) questionnaires at final follow-up. The mean age of the 23 included patients was 57.9 (standard deviation [s.d.]: 11.4) years and the mean duration of ED was 8.5 (s.d.: 7.9) years. Erection improvement was determined by comparing mean preoperative and postoperative IIEF-5 scores (8.3 [s.d.: 3.9] vs 24.6 [s.d.: 0.6], P < 0.001). High treatment satisfaction was determined according to a mean EDITS score of 94.9 (s.d.: 9.9). The proposed Ghattas technique was safe and effective in our patients, and provides opportunity for cases that need a diameter larger than 13 mm. Further studies are needed to confirm these results.


Subject(s)
Child , Erectile Dysfunction/surgery , Humans , Male , Patient Satisfaction , Penile Prosthesis , Surgical Mesh , Surveys and Questionnaires , Treatment Outcome
8.
Asian Journal of Andrology ; (6): 171-175, 2022.
Article in English | WPRIM | ID: wpr-928501

ABSTRACT

Mesenchymal stem cells (MSCs) secrete various cytokines with angiogenic and neuroprotective effects. This study aimed to assess the effects of human umbilical cord Wharton's jelly-derived MSCs (hWJ-MSCs) on diabetes-related intracavernosal pressure (ICP) impairment in rats. hWJ-MSCs were isolated from human umbilical cord Wharton's jelly and transplanted into the corpus cavernosum of streptozotocin (STZ)-induced diabetic rats by unilateral injection. The erectile function was evaluated at 4 weeks, as well as the expression levels of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), endothelial nitric oxide synthase (eNOS), and insulin-like growth factor 1 (IGF1). STZ-induced diabetic rats showed impaired ICP, which was significantly improved by hWJ-MSC treatment. VEGF, eNOS, IGF1, and bFGF expression levels were higher in hWJ-MSC injection sites than those in control ones in STZ-induced diabetic rats. These results suggest that hWJ-MSC transplantation might improve diabetic erectile dysfunction through increased production of paracrine growth factors, highlighting a novel potential therapeutic option for erectile dysfunction.


Subject(s)
Animals , Cell Differentiation , Diabetes Mellitus, Experimental/therapy , Erectile Dysfunction/therapy , Humans , Male , Mesenchymal Stem Cell Transplantation/methods , Rats , Umbilical Cord , Vascular Endothelial Growth Factor A , Wharton Jelly
9.
Asian Journal of Andrology ; (6): 32-39, 2022.
Article in English | WPRIM | ID: wpr-928500

ABSTRACT

We aimed to evaluate ten-year outcomes of penile prosthesis (PP) implantation for the treatment of erectile dysfunction and to assess predictors of early prosthetic infection (EPI). We identified 549 men who underwent 576 PP placements between 2008 and 2018. Univariate and multivariate analyses were used to identify potential predictors of EPI. An EPI predictive nomogram was developed. Thirty-five (6.1%) cases of EPI were recorded with an explant rate of 3.1%. In terms of satisfaction, 82.0% of the patients defined themselves as "satisfied," while partner's satisfaction was 88.3%. Diabetes (P = 0.012), longer operative time (P = 0.032), and reinterventions (P = 0.048) were associated with EPI risk, while postoperative ciprofloxacin was inversely associated with EPI (P = 0.014). Rifampin/gentamicin-coated 3-piece inflatable PP (r/g-c 3IPP) showed a higher EPI risk (P = 0.019). Multivariate analyses showed a two-fold higher risk of EPI in diabetic patients, redo surgeries, or when a r/g-c 3IPP was used (all P < 0.03). We showed that diabetes, longer operative time, and secondary surgeries were the risk factors for EPI. Postoperative ciprofloxacin was associated with a reduced risk of EPI, while r/g-c 3IPP had higher EPI rates without an increased risk of PP explant. After further validation, the proposed nomogram could be a useful tool for the preoperative counseling of PP implantation.


Subject(s)
Erectile Dysfunction/surgery , Humans , Male , Patient Satisfaction , Penile Implantation , Penile Prosthesis , Penis/surgery , Tertiary Care Centers
10.
Article in Chinese | WPRIM | ID: wpr-927362

ABSTRACT

Data mining technology was adopted to analyze the rules of acupoint selection in treatment of erectile dysfunction with acupuncture and moxibustion. All of the articles for acupuncture and moxibustion in treatment of erectile dysfunction were searched from the databases, i.e. Chinese national knowledge infrastructure (CNKI), Wanfang database, VIP, Chinese biomedical literature database (SinoMed) and PubMed, and the clinical trials on erectile dysfunction treated with acupuncture and moxibustion were screened. The database was set up by using Excel 2019 and input into R 4.0.3, and then, the therapeutic method, use frequency of acupoint, meridian tropism, collection visualization analysis, cluster analysis and association rule analysis were summarized. A total of 240 articles were included, with 516 prescriptions and 145 acupoints involved. The methods for treatment of erectile dysfunction included acupuncture and moxibustion therapy, acupuncture, acupoint injection, electroacupuncture, etc. The acupoints with high use frequency were Guanyuan (CV 4), Shenshu (BL 23), Sanyinjiao (SP 6), Mingmen (GV 4), Zusanli (ST 36), Zhongji (CV 3), Ciliao (BL 32), Qihai (CV 6), Taixi (KI 3) and Taichong (LR 3). The meridians involved with high frequency were the bladder meridian of foot-taiyang, the conception vessel, the spleen meridian of foot-taiyin, etc. The common acupoint combination was Shangliao (BL 31), Zhongliao (BL 33), Ciliao (BL 32), Xialiao (BL 34) and Sanyinjiao (SP 6), Shenshu (BL 23), Guanyuan (CV 4). In association rule analysis (confidence ≥ 90%, support ≥ 20%), there were 27 association rules in total. The acupoint combination with the highest support referred to "Shenshu (BL 23), Sanyinjiao (SP 6)→Guanyuan (CV 4)" (support 46.7%) and the acupoint combination with the highest confidence was "Sanyinjiao (SP 6), Qihai (CV 6)→Guanyuan (CV 4)" (confidence 98.0%). The acupoints could be divided into 5 effective clusters. Acupuncture and moxibustion therapy has a certain of rules of acupoint selection in treatment of erectile dysfunction, which provides the evidences for modern clinical trial and treatment.


Subject(s)
Acupuncture Points , Acupuncture Therapy , Data Mining , Erectile Dysfunction/therapy , Humans , Male , Meridians , Moxibustion , Technology
11.
African Health Sciences ; 22(3): 1-12, 2022-10-26. Tables
Article in English | AIM | ID: biblio-1400765

ABSTRACT

Background: Erectile dysfunction (ED) is a global public health problem that affects the quality of life, interpersonal, occupational, and social functioning of sufferers. Despite being high-risk groups, there is a paucity of data on erectile dysfunction among commercial vehicle drivers and motorcycle riders. Objectives: We aimed to determine and compare the prevalence and factors associated with ED among long-distance commercial vehicle drivers (CVDs) and commercial motorcycle riders (CMRs) in Ibadan, Nigeria. Methods: We used a comparative cross-sectional study design to enroll eligible male respondents in selected motor/motorcycle parks within Ibadan metropolis. Interviewer administered questionnaires were used to elicit sociodemographic/health-related characteristics, and ED status among participants. Data was analyzed using STATA version 12. Chi-square and Binary logistic regression were conducted to explore the association between ED and other covariates. Analyses were performed at 5% significance level. Results: The prevalence of ED was significantly higher among motorcycle riders than vehicle drivers (71.4% vs 47.4%, p = 0.001). Predictors of ED among CMRs were monogamous marriage type and history of perineal injury; while among CVRs were aged above 40-years, history of perineal injury, and current use of alcohol. Conclusion: There is a need for public education and awareness programmes on ED to reduce the burden and improve well-being in these populations


Subject(s)
Motorcycles , Global Health , Erectile Dysfunction , Interpersonal Relations , Motor Vehicles , Basic Training for Drivers , Nigeria
12.
Ann. afr. méd. (En ligne) ; 16(1): 4931-4938, 2022. tales, figures
Article in French | AIM | ID: biblio-1410559

ABSTRACT

Contexte et objectif. La maladie athéromateuse dont la coronaropathie étant une pathologie diffuse peut être prévenue par le contrôle des facteurs de risqué cardiovasculaire. Le but de cette étude était de décrire les caractéristiques pharmaco doppler pénien des patients coronariens souffrant de dysfonction érectile. Méthodes. Il s'agissait d'une série analytique des cas suivie entre juin 2020 et février 2021. Elle concernait des patients ayant des lésions athéromateuses significatives à la coronographie et souffrant de dysfonction érectile. Nous avons évalué les caractéristiques pharmaco doppler pénien. La qualité d'érection était appréciée par le score de rigidité Erectile Hardness Score (EHS). Résultats. Trente-six patients étaient inclus. L'âge moyen était de 56 ± 8,4 ans. le pic de Vitesse systolique au repos (PSVr) moyen des patients était de 13,7 cm/s ± 5,9. Le pic de vitesse systolique post injection (PSV pi) moyen des patients était de 23,9 cm/s ± 5,4. Les causes étaient principalement artérielles de 75%. La qualité d'érection était appréciée selon le score EHS : E1 (83%), E2 (22%), E3 (5%) et E4 (3%). Conclusion. La dysfunction érectile est associée aux facteurs de risque cardiovasculaire selon plusieurs études. L'echodoppler pénien avait occupé une place importante dans le diagnostic étiologique. Les causes retrouvées étaient principalement artérielles avec une baisse de PSVpi<25 cm/s.


Subject(s)
Humans , Coronary Artery Disease , Heart Disease Risk Factors , Blood Pressure , Coronary Vessels , Erectile Dysfunction
13.
Bull. méd. Owendo (En ligne) ; 20(51): 6-12, 2022. tables
Article in French | AIM | ID: biblio-1378024

ABSTRACT

Introduction : Les urgences péniennes sont multiples et variées. Elles peuvent mettre en jeu le pronostic fonctionnel sexuel du patient. L'objectif de notre étude était de rapporter les aspects cliniques et thérapeutiques des urgences péniennes au CHU de Libreville. Matériel et Méthodes : Nous avons réalisé une étude rétrospective de janvier 2016 à décembre 2020 au service d'urologie du CHU de Libreville. Les variables comprenaient les données sociodémographiques, cliniques et thérapeutiques des patients pris en charge pour une urgence pénienne. Résultats : Durant cette période, 63 patients ont été pris en charge pour urgences péniennes. L'âge moyen était de 27±17,3 ans avec des extrêmes de 1 et 90 ans. Les urgences péniennes les plus fréquentes étaient le priapisme (55,5%) et la fracture de verge (15,9%). Le délai moyen de consultation en urologie était de 121 343,3 heures pour une médiane de 10 heures tandis que celui de prise en charge était de 34,3±74,6 pour une médiane de 2 heures. Les principaux gestes effectués étaient la ponction des corps caverneux (n=29, 46%) suivie de l'albuginorraphie (n=9, 14,3%) et du shunt caverno spongieux (n=9, 14,3%). Conclusion : Les urgences péniennes sont relativement fréquentes. Elles sont dominées par le priapisme et la fracture de verge dans notre contexte. Le pronostic fonctionnel sexuel est bon mais le délai de prise en charge demeure encore long.


Introduction: Penile emergencies are multiple and varied. They can jeopardize the patient's functional sexual prognosis. The objective of our study was to report the clinical and therapeutic aspects of penile emergencies at the University Hospital of Libreville. Material and Methods: We conducted a retrospective study from January 2016 to December 2020 at the Urology Department of the CHU of Libreville. Variables included sociodemographic, clinical and therapeutic data of patients managed for a penile emergency. Results: During this period, 63 patients were managed for penile emergencies. The mean age was 27±17.3 years with extremes of 1 and 90 years. The most frequent penile emergencies were priapism (55.5%) and penile fracture (15.9%). The mean time to consultation in urology was 121,343.3 hours with a median of 10 hours, while the mean time to management was 34.3±74.6 with a median of 2 hours. The main procedures performed were corpora cavernosa puncture (n=29, 46%) followed by albuginorraphy (n=9, 14.3%) and cavernospongiosus shunt (n=9, 14.3%). Conclusion: Penile emergencies are relatively frequent. They are dominated by priapism and penile fracture in our context. The sexual functional prognosis is good but the delay of management remains long.


Subject(s)
Humans , Male , Adult , Middle Aged , Aged , Aged, 80 and over , Penile Diseases , Priapism , Surgical Procedures, Operative , Academic Medical Centers , Erectile Dysfunction
14.
urol. colomb. (Bogotá. En línea) ; 31(2): 82-92, 2022. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1412019

ABSTRACT

Objetivo Exponer los factores que han sido asociados al desarrollo de disfunción eréctil (DE) en las personas con virus de la inmunodeficiencia humana (VIH) y cuál es la prevalencia de la disfunción eréctil en esta población. Métodos Se realizó una revisión de alcance utilizando las siguientes bases de datos: MEDLINE, CENTRAL, Embase, Scopus, Lilacs, y Psycinfo. Los artículos incluidos debían tener cualquier información relacionada con la DE en personas con VIH, su prevalencia, y posibles factores asociados. Se filtraron un total de 2.726 artículos por título y resumen, y, de estos, se seleccionaron 22 referencias para revisión de texto completo y análisis. Resultados Se encontró que las personas con VIH tienen una mayor probabilidad de presentar DE en comparación con las personas sin VIH. Algunos estudios han establecido una asociación entre la DE y trastornos psicológicos o factores orgánicos, como la lipodistrofia, la hipertensión arterial, la hipercolesterolemia, la diabetes mellitus, la depresión, la ansiedad, y el hipogonadismo. La ingesta de terapia antirretroviral (TARV), más específicamente los inhibidores de la proteasa, sigue siendo cuestionada como causante de DE en pacientes con VIH. Conclusiones Ante un paciente con diagnóstico de VIH, se debe ahondar sobre DE con el fin de recomendar e iniciar conductas terapéuticas que aseguren un mejoramiento en su calidad de vida.


Aim To present factors that have been associated with the development of erectile dysfunction (ED) in people with human immunodeficiency virus (HIV) and the frequency of erectile dysfunction among this population. Methods We performed a scoping review on the following databases: MEDLINE, CENTRAL, Embase, Scopus, Lilacs, and Psycinfo. The articles included information related to ED in people with HIV, its frequency, and possible associated factors. A total of 2,726 articles were filtered by title and abstract, and, from these, 22 references were selected for full-text review and analysis. Results People with HIV were found to be more likely to have ED compared to people without HIV. Some studies have established an association between ED and psychological disorders or organic factors, such as lipodystrophy, high blood pressure, hypercholesterolemia, diabetes mellitus, depression, anxiety, and hypogonadism. The intake of antiretroviral therapy (ART), more specifically protease inhibitors, continues to be questioned as a cause of ED in patients with HIV. Conclusions In HIV-positive men, we recommend to actively seek ED in order to initiate therapeutic conducts that can ensure an improvement in their quality of life.


Subject(s)
Humans , Male , Quality of Life , HIV , Erectile Dysfunction , Anxiety , Peptide Hydrolases , Protease Inhibitors , Therapeutic Approaches , Alkalies , Hypercholesterolemia , Lipodystrophy
15.
Article in Spanish | LILACS, COLNAL | ID: biblio-1412077

ABSTRACT

La prostatectomía radical (PR) es uno de los pilares en el manejo del cáncer próstata. Esta cirugía constituye un reto para el urólogo, quien debe encontrar un balance entre el riesgo de extensión extraprostática y el grado de preservación del tejido neural. A pesar del avance en técnicas quirúrgicas, la incontinencia urinaria y disfunción eréctil (DE) post-prostatectomía continúan impactando considerablemente la calidad de vida de los pacientes. Por lo anterior, un abordaje transdisciplinario desde el momento del diagnóstico es esencial para mejorar los desenlaces funcionales y oncológicos.


Radical prostatectomy (RP) is one of the mainstays in the management of prostate cancer. This surgery constitutes a challenge for the urologist, who must find a balance between the risk of extraprostatic extension and the degree of preservation of neural tissue. Despite advances in surgical techniques, post-prostatectomy urinary incontinence and erectile dysfunction (ED) continue to significantly impact the quality of life of patients. Therefore, a transdisciplinary approach from the time of diagnosis is essential to improve functional and oncologic outcomes.


Subject(s)
Humans , Male , Prostatectomy , Erectile Dysfunction , Prostatic Neoplasms , Quality of Life , Urinary Incontinence , Post and Core Technique
16.
urol. colomb. (Bogotá. En línea) ; 31(3): 21-29, 2022. ilus
Article in Spanish | LILACS, COLNAL | ID: biblio-1412083

ABSTRACT

La enfermedad cardiovascular aterosclerótica es la primera causa de muerte en todo el mundo, y la principal causa de años de vida perdidos por discapacidad (AVADs) en los adultos. Sus factores de riesgo son muy prevalentes en la población, y su ocurrencia se ha asociado con disfunción sexual tanto en hombres como en mujeres, debido a que comparten un mecanismo fisiopatológico similar en el caso de la disfunción eréctil en los hombres y potencialmente en la disfunción sexual femenina. Además, los trastornos mentales asociados (principalmente ansiedad y depresión) y los efectos adversos de los medicamentos antihipertensivos y antidepresivos también contribuyen a las disfunciones sexuales. Por otro lado, los inhibidores de la fosfodiesterasa 5 (iFDE5s) han demostrado seguridad y beneficios cardiovasculares en los hombres, y en las mujeres hay evidencia creciente de su utilidad en las disfunciones sexuales. En esta revisión, se presentan las implicaciones de la enfermedad cardiovascular aterosclerótica y su tratamiento en la vida sexual de hombres y mujeres, los efectos cardiovasculares de los tratamientos de las disfunciones sexuales, y la consejería a los pacientes.


Atherosclerotic cardiovascular disease is the leading cause of death worldwide and the leading cause of disability-adjusted life years (DALYs). Its risk factors are very prevalent in the population, and its occurrence has been associated with sexual dysfunction in both men and women, because they share a similar pathophysiological mechanism in the case of erectile dysfunction in men and potentially in female sexual dysfunction. Furthermore, associated mental disorders (mainly anxiety and depression) and the adverse effects of antihypertensive drugs and antidepressants also contribute to sexual dysfunction. On the other hand, phosphodiesterase 5 inhibitors (PDE5is) have shown safety and cardiovascular benefits in men, and in women there is growing evidence of their usefulness in female sexual dysfunctions. The present review describes the implications of atherosclerotic cardiovascular disease and its treatment on the sexual lives of men and women, the cardiovascular effects of the treatments for sexual dysfunctions, and patient counseling.


Subject(s)
Humans , Male , Female , Sexuality , Atherosclerosis , Phosphodiesterase 5 Inhibitors , Anxiety , Therapeutics , Cardiovascular Diseases , Phosphoric Diester Hydrolases , Depression , Disability-Adjusted Life Years , Erectile Dysfunction , Mental Disorders , Antidepressive Agents , Antihypertensive Agents
17.
Diagn. tratamento ; 26(4): 151-5, out-dez. 2021.
Article in Portuguese | LILACS | ID: biblio-1348616

ABSTRACT

Estamos testemunhando um aumento previsível de sobreviventes ao câncer em decorrência da sofisticação crescente dos tratamentos, porém esses pacientes enfrentam sintomas de longo prazo, com efeitos psicológicos, sendo a disfunção sexual o mais prevalente e duradouro e com tendência a piorar quando não tratada. O objetivo desse artigo é discutir o comprometimento da saúde sexual como um dos efeitos colaterais mais dramáticos dos tratamentos de câncer e propor algumas recomendações terapêuticas. O modelo atual de resposta sexual é biopsicossocial, considerando que pacientes fragilizados pelo diagnóstico e pelos tratamentos para o câncer apresentarão alterações em dimensões psicológicas, sociais, culturais e relacionais. A saúde sexual feminina fica comprometida com sintomas físicos e psicológicos e dificuldades relacionais. Sobreviventes de câncer da próstata apresentam capacidade erétil insuficiente para a penetração. A terapêutica tradicional busca melhorar a função erétil, mas há evidências de que essas intervenções são insuficientes por não abordar as sequelas psicológicas. A perda da intimidade sexual pode comprometer o relacionamento do casal, a satisfação com o relacionamento, a saúde física e mental e a qualidade de vida. Há evidências de eficácia de programas psicoeducacionais, com orientações ao casal antes e durante o tratamento, mindfulness e tratamento em grupo. Mesmo com evidências da necessidade de abordar a saúde sexual dos sobreviventes dos tratamentos de câncer, os profissionais de saúde justificam a não abordagem com a falta de capacitação e a de tempo. Apresentamos um modelo breve de treinamento dos profissionais de saúde para a abordagem da saúde sexual, com resultados promissores.


Subject(s)
Sexual Dysfunction, Physiological , Sexual Health , Mindfulness , Erectile Dysfunction , Neoplasms
19.
Diagn. tratamento ; 26(2): 79-84, abr.-jun. 2021.
Article in Portuguese | LILACS | ID: biblio-1280729

ABSTRACT

A doença de Peyronie, notória desde 1743, segue sendo um grande desafio na prática médica, com prevalência relevante e grande impacto na vida sexual dos casais. O tratamento cirúrgico é a principal modalidade terapêutica capaz de restabelecer a vida sexual nos pacientes com doença de Peyronie significativa. A escolha do momento de implementação do tratamento cirúrgico, bem como a escolha da técnica a ser empregada, varia de acordo com três pontos centrais: a fase da doença, a deformidade apresentada e a função erétil. Estes pilares para a decisão terapêutica do paciente com doença de Peyronie possuem nuances, não sendo simples a caracterização destes fatores em muitos casos. Uma avaliação pré-operatória criteriosa, fundamental para a melhor escolha terapêutica, exige experiência e um conhecimento aprofundado sobre o tema. O objetivo do presente artigo é promover uma ampla discussão acerca de fatores primordiais da avaliação pré-operatória de pacientes com doença de Peyronie.


Subject(s)
Penile Diseases , Penile Induration , Preoperative Care , Penile Implantation , Erectile Dysfunction
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