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1.
Rev. ADM ; 78(4): 235-239, jul.-ago. 2021. ilus
Article in Spanish | LILACS | ID: biblio-1337563

ABSTRACT

El mixoma odontogénico es una neoplasia de origen mesenquimal, con crecimiento lento pero localmente invasivo y agresivo, que cuenta con un aspecto histológico característico. Radiográficamente, la mayoría de las lesiones tienen un aspecto radiolúcido multilocular, descrito en la literatura como «panal de abejas¼ o «burbujas de jabón¼, que ocasionan desplazamiento dental y expansión corticales. En el ámbito histopatológico, se caracteriza por células estelares o fusiformes con prolongaciones citoplasmáticas, en una sustancia mucoide o mixoide con presencia o no de colágena, cuando contiene grandes cantidades de tejido fibroso celular maduro se le llama mixofibroma. Se presenta un caso clínico de hombre de 38 años, que acude al Hospital General de Uruapan, Michoacán con aumento de volumen en región maxilar derecha; se toma biopsia incisional y se emite el diagnóstico histopatológico de mixofibroma odontogénico, 33.6% de los casos se presenta en el maxilar, con una distribución uniforme por todas las áreas llegando a erosionar el seno maxilar. Tiene una tasa de recurrencia de 10 a 33%, y el tratamiento ideal es la resección en bloque con márgenes de seguridad (AU)


Odontogenic myxoma is a slow-growing locally invasive intraosseous lesion with defined microscopic appearance. Radiographic appearance, is described as multilocular radiolucent lesion, which is reported in scientific literature as «honeycomb¼ or «soap bubbles¼ appearance most of the time; it exhibits dental displacement and cortical expansion. Histopathologically, stellate and spindle cells with cytoplasmic processes are observed in a mucoid or myxoid substance, with or without collagen; when it contains large amounts of mature cellular fibrous tissue, it is called myxofibroma. The present article presents the case of a 38 year old male, who attended the General Hospital in Uruapan, Michoacán due to an increased volume in the right maxillary region. Incisional biopsy was performed and the histopathological diagnosis of odontogenic myxofibroma was emitted. 33.6% of cases occur in the maxilla with a uniform distribution throughout the areas, and can erode the maxillary sinus. It has a recurrence rate of 10 to 33%, therefore ideal treatment is bloc resection leaving safety margins (AU)


Subject(s)
Humans , Male , Adult , Fibroma , Myxoma , Biopsy/methods , Oral Surgical Procedures , Dental Service, Hospital , Mexico
2.
Rev. ADM ; 78(1): 7-12, ene.-feb- 2021. ilus, tab
Article in Spanish | LILACS | ID: biblio-1152232

ABSTRACT

El fibroma de fibroblastos gigantes (FFG), conocido también como fibroma de células gigantes, es una pápula o nódulo asintomático localizado en la encía, paladar y lengua, es del mismo color que la mucosa adyacente, de base sésil o pediculada, con superficie lisa o papilar que por lo general mide menos de 1 cm. Objetivo: Identificar las características demográficas e histopatológicas de los casos de FFG de un laboratorio privado de patología bucal en la Ciudad de México. Material y métodos: Se obtuvieron los datos de edad, sexo, diagnóstico presuntivo y definitivo de 122 casos de FFG de 2004 a 2019 con un total de 7,681 muestras. Se describe su distribución por edad, sexo y localización. Resultados: El rango de edad obtenido es de 1 a 84 años, con un promedio de X = 38 años, se presenta con mayor frecuencia en la segunda década de vida, con una razón de 1.6:1 mujer a hombre. La localización más frecuente es en lengua (46%); sin embargo, sólo 49.1% de los estudios especificaban este dato. Conclusión: La importancia de esta lesión es que clínicamente se parece a otras patologías de tejido fibroso, por lo tanto, se debe tener presente al FFG como diagnóstico diferencial (AU)


Giant cell fibroma (GCF) is an asymptomatic papule or nodule that is similar in color to the surrounding mucosa, with a sessile or pedunculated base. It is usually less than 1 cm in size and it features a smooth or papillary surface. Objective: To identify the demographic and histopathological characteristics of GCF cases in a private oral pathology laboratory in Mexico City. Material and methods: Data on age, sex, as well as on presumptive and definitive diagnosis of 122 GCF cases were obtained from 2004 to 2019 with a total of 7,681 samples. Its distribution by age, sex and localization is described. Results: The age range obtained is from 1 to 84 years, with a mean age of 38 years. Frequently during the second decade of life, the female to male ratio is 1.6:1. The most frequent location is the tongue (46%), however, only 60 of 122 studies specified this data. Conclusion: Since this lesion clinically resembles another fibrous tissue pathology, it is warranted to have prior knowledge on its clinical characteristics, as GCF should be regarded as a differential diagnosis (AU)


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Fibroma/classification , Giant Cell Tumors , Tongue/pathology , Biopsy , Data Interpretation, Statistical , Histological Techniques , Diagnosis, Differential , Age and Sex Distribution , Mexico/epidemiology
3.
Frontiers of Medicine ; (4): 116-124, 2021.
Article in English | WPRIM | ID: wpr-880943

ABSTRACT

Meigs' syndrome (MS), a rare complication of benign ovarian tumors, is easily misdiagnosed as ovarian cancer (OC). We retrospectively reviewed the clinical laboratory data of patients diagnosed with MS from 2009 to 2018. Serum carbohydrate antigen 125 and HE4 levels were higher in the MS group than in the ovarian thecoma-fibroma (OTF) and healthy control groups (all P < 0.05). However, the serum HE4 levels were lower in the MS group than in the OC group (P < 0.001). A routine blood test showed that the absolute counts and percentages of lymphocytes were significantly lower in the MS group than in the OTF and control groups (all P < 0.05). However, these variables were higher in the MS group than in the OC group (both P < 0.05). The neutrophil-to-lymphocyte ratio (NLR) was also significantly lower, whereas the lymphocyte-to-monocyte ratio was higher in the MS group than in the OC group (both P < 0.05). The NLR, platelet-to-lymphocyte ratio, and systemic immune index were significantly higher in the MS group than in the OTF and control groups (all P < 0.05). The hypoxia-inducible factor-1 mRNA levels were also significantly higher, whereas the glucose transporter 1, lactate dehydrogenase, and enolase 1 mRNA levels were lower in peripheral CD4


Subject(s)
Carcinoma, Ovarian Epithelial , Female , Fibroma , Humans , Laboratories , Meigs Syndrome/diagnosis , Ovarian Neoplasms , Retrospective Studies
5.
Article in English | WPRIM | ID: wpr-811114

ABSTRACT

BACKGROUND: Spontaneous disease stabilization of desmoid-type fibromatosis (DF) has been demonstrated in many reports, and the watchful waiting approach without any frontline treatment is becoming popular as an initial management strategy. In this study, we aimed to assess the disease stabilization rate and identify predictive factors for disease stabilization of DF in patients with conservative treatment.METHODS: We reviewed 76 patients with sporadic extra-abdominal DF who were managed with frontline conservative treatment in our institute. The minimum follow-up was 12 months. Stabilization was defined as radiological evidence of no change or continuous decrease in size of the tumor for six months or more. The primary endpoint was stabilization of DF. Possible patient-, disease-, and treatment-related factors predictive of disease stabilization were analyzed with multivariate analysis.RESULTS: At final follow-up, 54 of the 76 tumors (71%) were stable, and mean time to stabilization was 30.4 months (range, 7 to 112 months). On Kaplan-Meier survival analysis, the spontaneous stabilization rate was 25.4% at one year, 52.7% at two years, and 70.9% at three years. The mean time to spontaneous stabilization was longer in patients with ≤ 40 years of age (p = 0.022) or recurrence (p = 0.041). On multivariate analysis with the Cox proportional hazard method, recurrence (hazard ratio [HR], 1.79; p = 0.041) and younger age (HR, 2.04; p = 0.022) were identified as independent prognostic factors for longer time to disease stabilization.CONCLUSIONS: Frontline conservative treatment seems to be the optimal treatment for most patients with DF. Younger patients or those with recurrence may require longer time to spontaneous disease stabilization.


Subject(s)
Fibroma , Fibromatosis, Aggressive , Follow-Up Studies , Humans , Methods , Multivariate Analysis , Recurrence , Watchful Waiting
6.
Annals of Dermatology ; : 146-150, 2020.
Article in English | WPRIM | ID: wpr-811083

ABSTRACT

Solitary fibrous tumor (SFT) is a relatively uncommon mesenchymal neoplasm that usually arises in the pleura, but also has been reported in numerous extrapleural locations, including cutaneous site. The skin lesion presents as a circumscribed nodule or tumor, mainly on the head and neck. A 41-year-old male presented with 6 months history of nail lesion without symptom on the left third finger. The lesion is slightly yellowish discoloration with subungual erythematous nodule and distal onycholysis. Biopsy specimen from the nail lesion showed the spindle cells form patternless pattern with hypercellular and hypocellular area. And small blood vessels and dilated vascular spaces were present. The result of special stain for specimen showed that positive for CD34, Bcl-2, and CD99 but negative for S-100, FactorXIIIa, and smooth muscle action. Recognition of this uncommon location of SFT is important because of possible confusion with other subungual tumors, including glomus tumor, fibroma and other fibrohistiocytic tumors like dermatofibrosarcoma protuberans, superficial acral fibromyxoma and cellular digital fibroma. Here in, we report a case of SFT of subungual region. We think this case is interesting because of uncommon location and may be helpful to more understand the character of this disease.


Subject(s)
Adult , Biopsy , Blood Vessels , Dermatofibrosarcoma , Fibroma , Fingers , Glomus Tumor , Head , Humans , Male , Muscle, Smooth , Neck , Onycholysis , Pleura , Skin , Solitary Fibrous Tumors
8.
Article in Spanish | LILACS | ID: biblio-1058329

ABSTRACT

RESUMEN: El fibroma odontogénico central (FOC) es una neoplasia benigna poco frecuente que representa alrededor del 1.5% de los tumores odontogénicos intraóseos. Su presentación es exclusiva de huesos maxilares. Tiene origen mesodérmico, pudiendo derivar del folículo dentario, ligamento periodontal y/o la papila dental. Tradicionalmente presenta dos variantes histológicas: un tipo que es pobre en epitelio y otro tipo que es rico en epitelio con focos de material calcificado. En la mayoría de los casos muestra un crecimiento lento y progresivo que produce expansión cortical con o sin sintomatología. Radiográficamente es común observar una imagen radiolúcida y unilocular, raramente se pueden exhibir lesiones multiloculares y/o de radiolucidez mixta. El tratamiento indicado en la mayoría de los casos es la enucleación del tumor. El siguiente reporte de caso describe las características clínicas, imageneológicas e histopatológicas de una lesión mandibular con diagnóstico de FOC y cuyo tratamiento realizado fue la enucleación del tumor.


ABSTRACT: Central odontogenic fibroma (COF) is a rare benign neoplasm that accounts for about 1.5% of intraosseous odontogenic tumors. Its presentation is exclusively in the maxillary bones. It has a mesodermal origin, being able to derive from the dental follicle, periodontal ligament and/or the dental papilla. Traditionally, it has two histological variants: one type that is poor in epithelium and another type that is rich in epithelium with foci of calcified material. In most cases it shows a slow and progressive growth that produces cortical expansion with or without symptomatology. Radiographically, it is common to observe a radiolucent and unilocular image, but rarely multilocular lesions and / or mixed radiolucency can be exhibited. The treatment indicated in most cases is the enucleation of the tumor. The following case report describes the clinical, imaging and histopathological characteristics of a mandibular lesion diagnosed with FOC and whose treatment was enucleation of the tumor.


Subject(s)
Humans , Female , Adult , Odontogenic Tumors , Fibroma , Mandible , Maxilla , Neoplasms
9.
Rev. Fac. Odontol. Univ. Antioq ; 31(1): 162-170, July-Dec. 2019. graf
Article in English | LILACS | ID: biblio-1115199

ABSTRACT

ABSTRACT Fibroma is currently considered the most common reactive hyperplasia of fibrous connective tissue in response to local trauma in the oral cavity. This case deals with the excision of a traumatic fibroma using diode laser (Epic X, wavelength of 940nm, continuous mode, 5W power), whose energy is absorbed by hemoglobin and melanin (chromophores) and is indicated in soft tissue surgeries, favoring coagulation. The results are consistent with the benefits demonstrated in the scientific literature: better visibility in the surgical act due to achieved hemostasis, excellent postoperative phase due to the absence of pain and inflammation, with no need for analgesic medication, no use of sutures, no scarring and no recurrence. It is a safe and fast procedure that also allows performing a histopathological study without altering the tissues to be examined. In the case presented here, the histopathological study confirmed the presumptive diagnosis of fibroma.


RESUMEN El fibroma es considerado actualmente como la más común hiperplasia reactiva de tejido conectivo fibroso en respuesta a un trauma local en la cavidad bucal. En este caso se menciona la escisión de un fibroma traumático utilizando laser de diodo (Epic X, longitud de onda de 940nm, modo continuo, potencia 5W), cuya energía es absorbida por la hemoglobina y la melanina (cromóforos), indicado en cirugías de tejidos blandos, favoreciendo la coagulación. Los resultados están acordes con los beneficios demostrados en la literatura científica: mejor visibilidad en el acto quirúrgico por la hemostasia lograda, postoperatorio excelente por la ausencia de dolor e inflamación, sin necesidad de medicación analgésica ni uso de suturas, no produce aparición de cicatriz y no recidiva; ofrece seguridad y rapidez en el procedimiento. Permite la realización de estudio histopatológico sin alterar los tejidos a examinar. En el caso presentado, el estudio histopatológico comprobó el diagnóstico presuntivo de fibroma.


Subject(s)
Hyperplasia , Fibroma , Lasers
10.
Rev. chil. obstet. ginecol. (En línea) ; 84(5): 384-392, oct. 2019. ilus
Article in Spanish | LILACS | ID: biblio-1058165

ABSTRACT

RESUMEN Introducción y objetivos: La fibromatosis produce tumores benignos pero localmente agresivos, que afectan a los tejidos blandos. A nivel mamario, representa tan sólo el 0.2% de las neoplasias de la mama. Nuestro objetivo con el presente artículo es profundizar en el conocimiento de la fibromatosis mamaria, a través del estudio de dos casos clínicos, mostrando sus características clínico-radiológicas e histológicas, e intentar establecer un protocolo de actuación adecuado. Métodos: Estudio retrospectivo de dos casos clínicos de fibromatosis mamaria diagnosticados en el Hospital Universitario La Paz entre los años 2018 y 2019. Resultados: Presentaremos dos pacientes con diagnóstico de fibromatosis mamaria, ambas debutaron con la autopalpación de un nódulo mamario. Al realizarles una ecografía, se visualizó un nódulo sólido, mal definido y axila ecográficamente negativa, que precisó de biopsia-aspiración con aguja gruesa. En los dos casos, se decidió resección quirúrgica de la lesión. Seguimiento mediante exploración mamaria y pruebas de imagen periódicas. Conclusiones: Aunque se trata de una entidad benigna, la fibromatosis mamaria puede simular un proceso maligno, tanto clínica como radiológicamente, por lo que precisa de un estudio histológico. A pesar de que la diseminación metastásica es muy poco frecuente, no se debe olvidar el carácter agresivo a nivel local de esta patología, y sus altas tasas de recurrencia. Como tratamiento, se debe realizar una resección quirúrgica, aunque recientemente se ha contemplado la opción de vigilancia estrecha sin tratamiento. No existe evidencia científica que justifique la utilización de otros tratamientos como la radioterapia o el tratamiento hormonal.


ABSTRACT Introduction and objectives: Fibromatosis produces benign but locally aggressive tumours that affect soft tissues. At breast level, it represents only 0.2% of breast neoplasms. Our goal with this article is to increase knowledge on breast fibromatosis, through the study of two clinical cases; explaining their clinical-radiologic and histological characteristics. Additionally, try to establish an adequate protocol, for the management of the disease and for its subsequent monitoring. Methods: A retrospective study about two clinical cases of breast fibromatosis diagnosed in La Paz Hospital between 2018-2019. Results: both patients presented with clinical manifestations, autopalpation of a breast nodule. A breast ultrasound was performed and a solid nodule was visualized, with poorly defined edges and ecographically negative armpit. A core needle biopsy was performed to confirm the histological diagnosis. In both clinical cases, the treatment was surgical resection of the lesion. Periodic revisions are being performed in order to exclude recurrence. Conclusions: Although it is a benign disease, breast fibromatosis can simulate a malignancy, both in a clinical and radiological way, so histological study is mandatory in order to achieve an accurate diagnosis. Even metastatic dissemination is extremely rare, the local aggressive nature and high rates of recurrence for fibromatosis makes surgical excision, with wide free margins, the most important tool in treatment, although the possibility of close surveillance without treatment is recently being contemplated. There is no scientific evidence to justify the use of other treatments such as radiotherapy or hormonal treatment.


Subject(s)
Humans , Female , Adult , Breast Neoplasms/diagnostic imaging , Fibromatosis, Aggressive , Fibroma/surgery , Fibroma/diagnostic imaging , Breast Neoplasms/surgery , Magnetic Resonance Imaging , Ultrasonography, Mammary
12.
Rev. bras. ortop ; 54(5): 491-496, Sept.-Oct. 2019. tab, graf
Article in English | LILACS | ID: biblio-1057937

ABSTRACT

Abstract Superficial acral fibromyxoma is a benign and rare tumor of the soft tissues. It usually manifests itself through a painless mass of slow growth that affects mainly males in the fifth decade of life. It usually affects the distal region, with a polypoid or dome-shaped appearance. The histological appearance is of a dermal mass without capsule, with spindle-shaped fibroblasts in a storiform or fasciculated pattern in the myxocollagenous stroma. The immunohistochemical evaluation of superficial acral fibromyxoma is usually positive for CD34 and CD99, with variable positivity for epithelial membrane antigen. The treatment consists of complete excision of the tumor mass. A review of the current literature on superficial acral fibromyxoma was performed, with an emphasis on the number of cases reported, location, diagnostic methods, histological characteristics, differential diagnoses and treatment. A total of 314 reported cases of superficial acral fibromyxoma with variable locations were found in the current literature, mainly in the toes (45.8%) and fingers (39.1%). It has a slightly superior incidence in men (61%) and enormous variability in the age range of occurrence. Superficial acral fibromyxoma is a single soft-tissue tumor that should enter the differential diagnosis of periungual and subungual acral lesions; the treatment consists of simple excision. More studies are needed to better understand this pathology, which was first described in 2001.


Resumo O fibromixoma acral superficial é um tumor raro de tecidos moles. Geralmente se manifesta por meio de uma massa indolor de crescimento lento que acomete principalmente adultos do sexo masculino na quinta década de vida. Ele normalmente afeta a região distal, com aparência polipoide. A aparência histológica é de uma massa dérmica sem cápsula, com fibroblastos fusiformes em estroma mixocolagenoso. A avaliação imuno-histoquímica do fibromixoma acral superficial normalmente é positiva para CD34 e CD99, com positividade variável para o antígeno epitelial de membrana. O tratamento consiste na exérese completa da massa tumoral. Foi feita uma revisão da literatura atual sobre o fibromixoma acral superficial com ênfase na quantidade de casos relatados, na localização, nos métodos diagnósticos, nas características histológicas, nos diagnósticos diferenciais, e no tratamento. Foram encontrados na literatura atual 314 casos descritos de fibromixoma acral superficial com localização variada, principalmente em pododáctilos (45,8%) e quirodáctilos (39,1%). Este tumor tem acometimento ligeiramente superior em homens (61%), e enorme variabilidade na faixa etária de acometimento. O fibromixoma acral superficial é um tumor de tecido mole único que deve entrar no diagnóstico diferencial das lesões periungueais e subungueais acrais; o tratamento consiste da exérese simples. Mais estudos são necessários para que se conheça melhor essa patologia, descrita em 2001.


Subject(s)
Skin Neoplasms , Soft Tissue Neoplasms , Fibroma/pathology , Fibroma/therapy
14.
Int. j. med. surg. sci. (Print) ; 6(3): 96-100, sept. 2019. ilus
Article in English | LILACS | ID: biblio-1247413

ABSTRACT

Introduction: Odontogenic mixomas (OMs) are a locally infiltrating slow-growing intraosseous nonmetastasizing tumors of the maxilla and the mandible that have the potential for bone des-truction and cortical expansion, showing high recurrence rates. Their frequency varies around the world, accounting for 3-20% of all odontogenic tumors, ranking third among odontogenic tumors. They predominantly affect young adults, but may occur in various age groups. Report: A 37-year-old female patient who in August 2005 sought treatment at the Maxillofacial Dental Unit at Hospital Higueras, Talcahuano, Chile, for a left maxillary bone lesion. An increase in vo-lume was observed in the left maxillary region in the clinical analysis of the oral cavity. The neo-plasm was sessile and painless, measuring approximately 3 cm, with a greater diameter in the vestibule, firm on palpation and without signs of gangliopathy. Computed cone beam tomogra-phy imaging showed an extensive infiltrating osteolytic lesion in the left maxillary sinus, with noinvolvement of the orbital bone structure. Analysis of incisional biopsy yielded the diagnosis ofOdontogenic Fibromixoma. It was proposed to perform the conservative treatment of the lesion,consisting of enucleation and surgical curettage, obtaining excellent postoperative results and absence of relapse after 11-year follow-up. Conclusion: The present case report provides eviden-ce that supports the conservative surgical approach for the treatment of odontogenic myxomas, which contributes to a better postoperative quality of life for the patient.


Subject(s)
Humans , Female , Adult , Maxillary Neoplasms/surgery , Odontogenic Tumors/surgery , Fibroma/surgery , Fibroma/diagnosis , Biopsy/methods , Tomography, X-Ray Computed/methods , Maxilla/pathology
15.
Braz. j. otorhinolaryngol. (Impr.) ; 85(4): 399-407, July-Aug. 2019. tab, graf
Article in English | LILACS | ID: biblio-1019582

ABSTRACT

Abstract Introduction Reactive hyperplastic lesions develop in response to a chronic injury simulating an exuberant tissue repair response. They represent some of the most common oral lesions including inflammatory fibrous hyperplasia, oral pyogenic granuloma, giant cell fibroma, peripheral ossifying fibroma, and peripheral giant cell lesions. Objective The incidence of those lesions was investigated in an oral pathology service, and the clinical characteristics, associated etiological factors, concordance between the clinical and histopathological diagnostic was determined. Methods A total of 2400 patient records were screened from 2006 to 2016. Clinical features were recorded from biopsy reports and patients' files. Results A total of 534 cases of reactive hyperplastic lesions were retrieved and retrospectively studied, representing 22.25% of all diagnoses. The most frequent lesion was inflammatory fibrous hyperplasia (72.09%), followed by oral pyogenic granuloma (11.79%), giant cell fibroma (7.30%), peripheral ossifying fibroma (5.24%), and peripheral giant cell lesions (3.55%). Females were predominantly affected (74.19%), the gingiva and alveolar ridge were the predominant anatomical site (32.89%), and chronic traumatism was presented as the main etiological factor. The age widely ranges from the 1st decade of life to the 7th. Clinically, the reactive hyperplastic lesions consisted of small lesions (0.5-2 cm) and shared a strong likeness in color to the oral mucosa. The concordance between the clinical and histopathological diagnostic was high (82.5%). Conclusion Reactive hyperplastic lesions had a high incidence among oral pathologies. The understanding of their clinical features helps to achieve a clearer clinical and etiological diagnosis, and the knowledge of factors related to their development. This may contribute to adequate treatment and positive prognosis.


Resumo Introdução As lesões hiperplásicas reativas se desenvolvem em resposta a uma lesão crônica que estimula uma resposta acentuada de reparo tecidual. Elas representam uma das lesões orais mais comuns, inclusive hiperplasia fibrosa inflamatória, granuloma piogênico oral, fibroma de células gigantes, fibroma periférico ossificante e lesão periférica de células gigantes. Objetivo A incidência dessas lesões foi investigada em um serviço de patologia bucal e as características clínicas, os fatores etiológicos associados e a concordância entre os diagnósticos clínico e histopatológico foram determinados. Método Foram selecionados 2.400 registros de pacientes entre 2006 e 2016. As características clínicas foram registradas a partir de laudos de biópsia e dos prontuários dos pacientes. Resultados Um total de 534 casos de lesões hiperplásicas reativas foram recuperados e retrospectivamente estudados, representando 22,25% de todos os diagnósticos. A lesão mais frequente foi hiperplasia fibrosa inflamatória (72,09%), seguida por granuloma piogênico oral (11,79%), fibroma de células gigantes, (7,30%), fibroma periférico ossificante (5,24%) e lesão periférica de células gigantes (3,55%). O sexo feminino foi predominante (74,19%), a gengiva e a crista alveolar foram o local anatômico predominante (32,89%) e o traumatismo crônico foi demonstrado como o principal fator etiológico. A idade variou desde a 1ª década de vida até a 7ª. Clinicamente, as LHR consistiram em pequenas lesões (0,5 a 2 cm) que apresentaram uma forte semelhança de cor com a mucosa oral. A concordância entre o diagnóstico clínico e histopatológico foi alta (82,5%). Conclusão As lesões hiperplásicas reativas apresentaram alta incidência entre as patologias bucais. A compreensão das características clínicas ajuda na realização de um diagnóstico clínico e etiológico mais claro, bem como determinar os fatores relacionados ao seu desenvolvimento. Dessa forma contribui para um tratamento adequado e um prognóstico positivo.


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Young Adult , Hyperplasia/pathology , Mouth/pathology , Mouth Diseases/pathology , Giant Cells/pathology , Retrospective Studies , Granuloma, Pyogenic/congenital , Granuloma, Pyogenic/pathology , Fibroma, Ossifying/etiology , Fibroma, Ossifying/pathology , Fibroma/etiology , Fibroma/pathology , Hyperplasia/classification , Hyperplasia/etiology , Mouth Diseases/classification , Mouth Diseases/diagnosis , Mouth Diseases/etiology , Mouth Mucosa/pathology
16.
Rev. colomb. reumatol ; 26(2): 140-144, ene.-jun. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1115673

ABSTRACT

RESUMEN Objetivo: Describir el comportamiento clínico y epidemiológico de la contractura de Dupuytren (CD) en la población colombiana y comparar nuestros resultados con otras series publicadas en la literatura. Materiales y métodos: Estudio descriptivo observacional de 33 casos de CD presentados en el hospital San Pedro y San Pablo de la Virginia, Risaralda, durante los últimos 6 arios. Los pacientes cumplieron con el diagnóstico de CD de acuerdo con el parámetro establecido. Se compararon los resultados con diferentes series de casos de CD publicadas en la literatura. Resultados: La edad promedio al momento del diagnóstico fue de 61,3 años con mayor prevalencia en hombres (64% de los casos). La forma de presentación más frecuente fue unilateral en mano derecha (73%), a diferencia de lo reportado en otras series, donde el compromiso usualmente fue bilateral. La diabetes mellitus fue la comorbilidad con mayor asociación a la CD (24,24%), hallazgo similar a lo publicado previamente. La mayoría de los pacientes requirió tratamiento quirúrgico. Conclusiones: La CD es una entidad de mayor ocurrencia en hombres de la sexta a la séptima década de la vida. La diabetes mellitus es la enfermedad que más se asocia a su aparición, sin encontrase diferencias entre los estudios realizados. En población colombiana no hay relación aparente con epilepsia. La presentación de la CD es variable, encontrándose en nuestra serie un mayor compromiso unilateral a diferencia de otras poblaciones donde la presentación usualmente es bilateral.


ABSTRACT Objective: To describe the clinical and epidemiological behavior of Dupuytren's contracture (DC) in the Colombian population, and to compare the results of this study with other series published in the literature. Materials and methods: A descriptive, observational study of 33 cases of DC presented at the Hospital San Pedro y San Pablo, La Virginia Risaralda, over the last 6 years. The patients were diagnosed with DC according to the established parameter. The results were compared against different series of DC cases published in the literature. Results: The mean age at diagnosis was 61.3 years, with a higher prevalence of men (64% of cases). The most frequent form of presentation was unilateral in the right hand (73%), unlike the reports from other series with usually bilateral involvement. Diabetes mellitus was the comorbidity most often associated with DC (24.24%), a finding similar to those of previous publications. Most patients required surgical treatment. Conclusions: DC is a condition that occurs more often in men in the sixth or seventh decade of life. Diabetes mellitus is the most frequently associated disease, with no differences being found among the various studies. In the Colombian population there is no apparent association with epilepsy. The presentation of DC is variable, but our series showed more unilateral involvement as compared to other populations where the presentation is usually bilateral.


Subject(s)
Humans , Male , Middle Aged , Dupuytren Contracture , Diabetes Mellitus , Myofibroblasts , Fibroma
17.
Rev. chil. radiol ; 25(2): 67-70, jun. 2019. ilus
Article in Spanish | LILACS | ID: biblio-1013851

ABSTRACT

El tumor desmoides es un tumor benigno raro, de origen fibroblastico no inflamatorio, algunas veces referido como fibromatosis no agresiva. Su etiología aún no está completamente clara, sin embargo, se asocia habitualmente a trauma previo y/o procedimientos quirúrgicos. La ubicación más frecuente es abdominal, el cual posee características imagenologicas claras, al igual que su presentación musculo esquelética plantar. La presentación fuera de estos lugares es infrecuente y difícil de diagnosticar. Presentamos un caso de un tumor desmoides cervical que genero un gran desafío diagnóstico, identificando sus claves diagnósticas y realizando una revisión de la bibliografía al respecto para esta ubicación.


Desmoid tumours are a rare benign tumour of fibroblastic non inflammatory origin, sometimes referred as non aggressive fibromatosis.The etiology is not yet completely clear, however, it is usually associated with previous trauma and / or surgical procedures. The most frequent location is in the abdomen, which has typical images characteristics, as well as its skeletal muscle presentation at the plantar level. The presentation outside these places is infrequent and difficult to diagnose. We present a case of a cervical desmoid tumour that generated a great diagnostic challenge, identifying its key imaging characteristics and performing a literature review of the bibliography regarding this location.


Subject(s)
Humans , Male , Adult , Fibroma/surgery , Fibroma/diagnostic imaging , Head and Neck Neoplasms/surgery , Head and Neck Neoplasms/diagnostic imaging , Tomography, X-Ray Computed , Fibroma/pathology , Head and Neck Neoplasms/pathology
18.
Rev. Odontol. Araçatuba (Impr.) ; 40(2): 43-47, maio/ago. 2019. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-1006564

ABSTRACT

O objetivo deste estudo é descrever o diagnóstico e conduta clínica no tratamento do Fibroma Traumático (FT). O FT é uma lesão proliferativa de natureza benigna que surge na cavidade bucal devido à traumas de repetição, que desencadeiam reações inflamatórias em tecido conjuntivo, causando uma hiperplasia tecidual, geralmente assintomática, podendo interferir na mastigação e na fala causando desconforto ao paciente. Sua prevalência é alta, geralmente em mucosa jugal, linha oclusal, mucosa labial, língua e gengiva. O tratamento consiste na excisão cirúrgica e a confirmação do diagnóstico é dado através de envio para exame histopatológico. Paciente do gênero masculino, 46 anos de idade, procurou atendimento por apresentar nódulo único, exofítico, unilateral de aproximadamente 3 cm em seu diâmetro, localizado na mucosa jugal do lado direito, com bordas regulares e indolor a palpação, apresentando há cerca de 12 meses. Foi submetido a remoção cirúrgica total da lesão e encaminhamento ao laboratório para análise histopatológica para confirmação diagnóstica, além de proservação do caso em 7, 30 e 60 dias. Desta forma, foi possível concluir que a excisão cirúrgica da lesão promove maior conforto, melhora na fala e mastigação, além de um bom reparo tecidual, devolvendo assim, condições de saúde a mucosa bucal e mínimas chances de recidiva(AU)


The objective of this study is to describe the diagnosis and clinical management in the treatment of Traumatic Fibroma (FT). FT is a proliferative lesion of benign nature that arises in the buccal cavity due to repetitive traumas, which trigger inflammatory reactions in connective tissue, causing a tissue hyperplasia, usually asymptomatic, that can interfere in chewing and speech causing discomfort to the patient. Its prevalence is high, usually in jugal mucosa, occlusal line, labial mucosa, tongue and gingiva. The treatment consists of surgical excision and confirmation of the diagnosis is given by sending for histopathological examination. A 46-year-old male patient sought care for having a single, exophytic, unilateral nodule of approximately 3 cm in diameter, located on the right side of the jugal mucosa, with regular borders and painless palpation, presenting about 12 months. He was submitted to total surgical removal of the lesion and sent to the laboratory for histopathological analysis for diagnostic confirmation, in addition to case proservation at 7, 30 and 60 days. In this way, it was possible to conclude that the surgical excision of the lesion promotes greater comfort, improvement in speech and chewing, besides a good tissue repair, thus returning health conditions to the oral mucosa and minimal chances of relapse(AU)


Subject(s)
Humans , Male , Middle Aged , Fibroma/surgery , Surgery, Oral , Fibroma , Fibroma/diagnosis , Fibroma/therapy , Hyperplasia , Mouth Mucosa/pathology
19.
Rev. pediatr. electrón ; 16(1): 6-12, abr. 2019.
Article in Spanish | LILACS | ID: biblio-998405

ABSTRACT

Los tumores cardiacos primarios fetales representan una entidad de baja incidencia en la práctica clínica. La gran mayoría corresponde a lesiones benignas, siendo el rabdomioma el tipo más común. Si bien, es frecuente la regresión espontánea de este tipo de lesiones durante el embarazo, los tumores cardiacos fetales pueden asociarse a complicaciones como obstrucción del flujo cardíaco, insuficiencia valvular, arritmias, insuficiencia cardíaca e hidrops fetal, pudiendo conducir incluso a la muerte fetal. El mayor desarrollo de técnicas imagenológicas ha permitido un aumento en el número y precisión de los diagnósticos prenatales de tumores cardiacos, generando al mismo tiempo, nuevos desafíos y alternativas en relación al abordaje terapéutico. El objetivo del presente artículo de revisión es exponer la evidencia actual en relación al diagnóstico prenatal, manejo, complicaciones y condiciones asociadas de los tumores cardiacos fetales más frecuentes.


Fetal primary cardiac tumors represent a low incidence entity in clinical practice. The vast majority corresponds to benign lesions, with rhabdomyoma being the most common type. Although spontaneous regression of this type of lesions during pregnancy is frequent, fetal cardiac tumors can be associated with complications such as obstruction of cardiac flow, valvular insufficiency, arrhythmias, heart failure and fetal hydrops, which can even lead to fetal death. The greater development of imaging techniques has allowed an increase in the number and precision of prenatal diagnoses of cardiac tumors, generating at the same time, new challenges and alternatives in relation to the therapeutic approach. The objective of this review article is to present the current evidence regarding the prenatal diagnosis, management, complications and associated condition s of the most frequent fetal cardiac tumors.


Subject(s)
Humans , Female , Pregnancy , Fetus/diagnostic imaging , Heart Neoplasms/diagnostic imaging , Rhabdomyoma/diagnostic imaging , Teratoma/diagnostic imaging , Ultrasonography, Prenatal , Fibroma/diagnostic imaging , Heart Neoplasms/therapy , Myxoma/diagnostic imaging
20.
Int. j. odontostomatol. (Print) ; 13(1): 58-63, mar. 2019. graf
Article in Spanish | LILACS | ID: biblio-990065

ABSTRACT

RESUMEN: El fibromixoma odontogénico (FM) es una infrecuente lesión benigna que muestra un comportamiento invasivo. Considerada una variante del mixoma odontogénico, presenta un origen mesenquimal controvertido y ligera predilección por el sexo femenino. La lesión está asociada a zonas con estructuras dentales adyacentes, siendo su localización más frecuente la región mandibular posterior. El objetivo de este trabajo fue mostrar un caso agresivo de FM en una paciente, localizado en la zona posterior de maxila, destacando su abordaje quirúrgico. Se reporta un caso de una mujer de 52 años, la cual acudió a la consulta por presentar una masa indolora, firme a la palpación en el lado derecho de la maxila. Radiográficamente se observaba como una imagen radiopaca, de márgenes mal definidos que se extendía en el seno maxilar ipsilateral; la tomografía computarizada pudo evidenciar la expansión de las paredes del antro y la fosa nasal, con compromiso del cigomático y el piso de órbita. Se realizó biopsia incisional y el diagnóstico histopatológico fue de FM. El tratamiento de elección consistió en la resección en bloque, mediante abordaje Weber-Fergusson, acompañada de reconstrucción con placa y malla de titanio para garantizar la suspensión del globo ocular; un nuevo estudio histopatológico, confirmó el diagnóstico inicial. Al año del procedimiento quirúrgico no se evidenció recidiva, observando que el material de reconstrucción mantiene su posición, proporcionado estética y funcionabilidad a la paciente.


ABSTRACT: Odontogenic fibromyxoma (FM) is an infrequent benign lesion that shows with invasive characteristics. Considered a variant of the odontogenic myxoma, it presents a controversial mesenchymal origin and is somewhat more frequent in women. The lesion is associated with areas with adjacent dental structures, with its most frequent location in the posterior mandibular region. The objective of this study was to show an aggressive case of FM in a female, located in the posterior area of the maxilla, emphasizing its surgical approach. A case of a 52-year-old woman, who came to the clinic because of a painless, firm mass on the right side of the maxilla. Radiographically, it was seen as a radiopaque image, with poorly defined margins extending in the ipsilateral maxillary sinus; computed tomography showed the expansion of the walls of the antrum and the nasal cavity, with zygomatic compromise and the orbital floor. An incisional biopsy was performed and the histopathological diagnosis was FM. The treatment of choice consisted of block resection, using a WeberFerguson approach, along with reconstruction with a titanium plaque and mesh to guarantee suspension of the eyeball; a new histopathological study, confirmed the initial diagnosis. One year after the surgical procedure, there is no recurrence, and the reconstruction material maintains its position, providing aesthetic and functionality to the patient.


Subject(s)
Humans , Female , Middle Aged , Maxillary Neoplasms/surgery , Odontogenic Tumors/surgery , Fibroma/diagnosis , Radiography, Panoramic , Maxillary Neoplasms/diagnostic imaging , Odontogenic Tumors/diagnostic imaging , Tomography, X-Ray Computed , Fibroma/diagnostic imaging
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