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1.
Arq. gastroenterol ; 58(1): 93-99, Jan.-Mar. 2021. tab, graf
Article in English | LILACS | ID: biblio-1248989

ABSTRACT

ABSTRACT BACKGROUND: As age advances, a higher burden of comorbidities and less functional reserve are expected, however, the impact of aging in the surgical outcomes of gastric cancer (GC) patients is unknown. OBJECTIVE: The aim of this study is to evaluate surgical outcomes of GC patients according to their age group. METHODS: Patients submitted to gastrectomy with curative intent due to gastric adenocarcinoma were divided in quartiles. Each group had 150 patients and age limits were: ≤54.8, 54.9-63.7, 63.8-72, >72. The outcomes assessed were: postoperative complications (POC), 90-day postoperative mortality, disease-free survival (DFS) and overall survival (OS). RESULTS: Major surgical complications were 2.7% in the younger quartile vs 12% for the others (P=0.007). Major clinical complications raised according to the age quartile: 0.7% vs 4.7% vs 5.3% vs 7.3% (P<0.042). ASA score and age were independent risk factors for major POC. The 90-day mortality progressively increased according to the age quartile: 1.3% vs 6.0% vs 7.3% vs 14% (P<0.001). DFS was equivalent among quartile groups, while OS was significantly worse for those >72-year-old. D2 lymphadenectomy only improved OS in the three younger quartiles. Age >72 was an independent risk factor for worse OS (hazard ratio of 1.72). CONCLUSION: Patients <55-year-old have less surgical complications. As age progresses, clinical complications and 90-day mortality gradually rise. OS is worse for those above age 72, and D2 lymphadenectomy should be individualized after this age.


RESUMO CONTEXTO: Conforme a idade avança, se esperam mais morbidades e menor reserva funcional. Entretanto não está claro qual o impacto do envelhecimento nos resultados cirúrgicos do câncer gástrico (CaG). OBJETIVO: O intuito deste estudo é avaliar os resultados cirúrgicos de pacientes com CaG de acordo com o grupo etário. MÉTODOS: Pacientes submetidos a gastrectomia por adenocarcinoma gástrico com intuito curativo foram divididos em quartis. Cada grupo incluiu 150 indivíduos e os limites etários foram: ≤54,8; 54,9-63,7; 63,8-72; >72. Os resultados avaliados foram: complicações pós-operatórias (CPO), mortalidade em 90 dias, sobrevida livre de doença (SLD) e sobrevida global (SG). RESULTADOS: Complicações cirúrgicas maiores ocorreram em 2,7% dos pacientes no quartil mais jovem vs 12% para os demais (P=0,007). A incidência de complicações clínicas maiores aumentou conforme o quartil: 0,7% vs 4,7% vs 5,3% vs 7,3% (P<0,042). A pontuação ASA e a idade foram fatores de risco independentes para CPO maiores. A mortalidade em 90 dias aumentou progressivamente conforme o quartil etário: 1,3% vs 6,0% vs 7,3% vs 14% (P<0,001). A SLD foi equivalente entre os quartis, enquanto a SG foi significativamente pior para os >72 anos de idade. Linfadenectomia D2 aumentou a SG apenas para os 3 quartis mais jovens. Idade > 72 foi fator independente de risco para pior SG (razão de chances de 1,72) CONCLUSÃO: Pacientes < 55 anos tem menos complicações cirúrgicas. Conforme a idade avança, as complicações clínicas e a mortalidade em 90 dias aumenta gradualmente. A SG é pior se >72 anos e a indicação de linfadenectomia D2 deve ser individualizada a partir dessa idade.


Subject(s)
Humans , Aged , Stomach Neoplasms/surgery , Adenocarcinoma/surgery , Postoperative Complications , Survival Rate , Retrospective Studies , Gastrectomy/adverse effects , Lymph Node Excision , Middle Aged
2.
ABCD arq. bras. cir. dig ; 34(4): e1633, 2021. tab, graf
Article in English, Portuguese | LILACS | ID: biblio-1360020

ABSTRACT

RESUMO - RACIONAL: Disfunção do esfíncter esofágico inferior (EEI), doença do refluxo gastroesofágico e esofagite erosiva em pacientes submetidos à gastrectomia subtotal são ocorrências comumente reconhecidas, mas até agora as causas permanecem obscuras. OBJETIVO: A hipótese deste estudo é que a gastrectomia subtotal provoque alterações na pressão de repouso do EEI e na sua competência, devido ao dano anatômico desta, visto que as fibras oblíquas "Sling", um dos componentes musculares do EEI, são seccionadas durante este procedimento cirúrgico. MÉTODOS: Sete cães adultos sem raça definida (18-30 kg) foram anestesiados e submetidos à transecção do estômago proximal. Em seguida, o remanescente gástrico proximal foi fechado por sutura. No intraoperatório, manometria lenta foi realizada em cada cão, em condições basais (com estômago intacto) e no remanescente gástrico proximal fechado. A média dessas medidas é apresentada, com cada cão servindo como seu próprio controle. RESULTADOS: A pressão média do EEI medida no remanescente gástrico proximal, em comparação com a pressão do EEI no estômago intacto, foi diminuída em cinco cães, aumentada em um cão e sem alterações no outro cão. CONCLUSÃO: A secção transversa superior do estômago e o fechamento do remanescente do estômago por sutura provocam alterações na pressão do EEI. Sugerimos que essas mudanças na pressão do EEI são secundárias à secção das fibras oblíquas "Sling" do esfíncter, um de seus componentes musculares. A sutura e o fechamento do remanescente gástrico proximal, reancora essas fibras com mais, menos ou a mesma tensão, modificando ou não a pressão do EEI.


ABSTRACT - BACKGROUND: Dysfunction of the lower esophageal sphincter (LES), gastroesophageal reflux disease, and erosive esophagitis in patients undergoing subtotal gastrectomy are commonly recognized occurrences, but until now the causes remain unclear. AIM: The hypothesis of this study is that subtotal gastrectomy provokes changes on the LES resting pressure and its competence, due to the anatomical damage of it, given that the oblique "Sling" fibers, one of the muscular components of the LES, are transected during this surgical procedure. METHODS: Seven adult mongrel dogs (18-30 kg) were anesthetized and admitted for transection of the proximal stomach. Later, the proximal gastric remnant was closed by a suture. Intraoperatively, slow pull-through LES manometries were performed on each dog, under basal conditions (with the intact stomach), and in the closed proximal gastric remnant. The mean of these measurements is presented, with each dog serving as its control. RESULTS: The mean LES pressure (LESP) measured in the proximal gastric remnant, compared with the LESP in the intact stomach, was decreased in five dogs, increased in one dog, and remained unchanged in other dogs. CONCLUSION: The upper transverse transection of the stomach and closing the stomach remnant by suture provoke changes in the LESP. We suggested that these changes in the LESP are secondary to transecting the oblique "Sling" fibers of the LES, one of its muscular components. The suture and closing of the proximal gastric remnant reanchor these fibers with more, less, or the same tension, whether or not modifying the LESP.


Subject(s)
Humans , Animals , Dogs , Gastroesophageal Reflux , Esophageal Sphincter, Lower/surgery , Esophagogastric Junction , Gastrectomy/adverse effects , Manometry
3.
ABCD arq. bras. cir. dig ; 34(2): e1602, 2021. tab, graf
Article in English, Portuguese | LILACS | ID: biblio-1345018

ABSTRACT

ABSTRACT Background: Morbid obesity surgery and related complications have increased with time. Aim: To evaluate the relationship between perioperative complications before discharge and preoperative body mass index and obesity surgery mortality score in laparoscopic sleeve gastrectomy. Method: 1617 patients who met the inclusion criteria were evaluated retrospectively. The patients were examined in terms of demographic data, presence of comorbidities, whether there were complications or not, type of complications and obesity surgery mortality score. Results: Complications were seen in 40 patients (2.5%) and mortality wasn't seen in the early postoperative period before discharge. The mean age of patients with complications was 36.3±10.02 years (19-57) and without complications 34.12±9.54 (15-64) years. The preoperative mean BMI values of patients with and without complications were 45.05±3.93 (40-57) kg/m2 and 44.8±3.49 (35-67) kg/m2 respectively. According to BMI groups 40-45 kg/m2, 45-50 kg/m2 and 50 and over, there was not any statistical significance seen in three groups in terms of complication positivity and major-minor complication rates. There was not any statistical significance seen between the patients with and without major-minor complications and obesity surgery mortality score. Conclusion: There was not any relation between perioperative laparoscopic sleeve gastrectomy complication rates before discharge and BMI and obesity surgery mortality scores.


RESUMO Racional: A cirurgia da obesidade mórbida e complicações relacionadas aumentaram com o tempo. Objetivo: Avaliar a relação entre as complicações perioperatórias antes da alta e o índice de massa corporal pré-operatório e o escore de mortalidade da cirurgia de obesidade na gastrectomia vertical laparoscópica. Método: 1.617 pacientes que atenderam aos critérios de inclusão foram avaliados retrospectivamente. Os pacientes foram examinados quanto aos dados demográficos, presença de comorbidades, ocorrência ou não de complicações, tipo de complicações e escore de mortalidade cirúrgico da obesidade. Resultados: Complicações foram observadas em 40 pacientes (2,5%) e mortalidade não foi observada no período pós-operatório imediato antes da alta. A média de idade dos pacientes com complicações foi de 36,3±10,02 anos (19-57) e sem complicações de 34,12±9,54 (15-64) anos. Os valores médios de IMC pré-operatórios dos pacientes com e sem complicações foram 45,05±3,93 (40-57) kg/m2 e 44,8±3,49 (35-67) kg/m2, respectivamente. De acordo com os grupos de IMC 40-45 kg/m2, 45-50 kg/m2 e 50 e mais, não houve qualquer significância estatística observada em três grupos em termos de positividade de complicações e taxas de complicações maiores-menores. Não houve significância estatística entre os pacientes com e sem complicações maiores e menores e o escore de mortalidade da cirurgia de obesidade. Conclusão: Não houve qualquer relação entre as taxas de complicações da gastrectomia vertical laparoscópica perioperatória antes da alta e os escores de mortalidade da cirurgia de obesidade e IMC.


Subject(s)
Humans , Adult , Young Adult , Obesity, Morbid/surgery , Laparoscopy , Patient Discharge , Postoperative Complications/epidemiology , Weight Loss , Body Mass Index , Retrospective Studies , Follow-Up Studies , Treatment Outcome , Gastrectomy/adverse effects , Middle Aged
4.
Rev. cuba. enferm ; 36(4): e3269, tab
Article in Portuguese | LILACS, BDENF, CUMED | ID: biblio-1280290

ABSTRACT

Introdução: A síndrome metabólica constitui-se em um dos fatores de risco cardiovascular e as estratégias para seu enfrentamento são indispensáveis para reduzir a morbimortalidade da população. Objetivo: Identificar os diagnósticos de ernfermagem e intervenções realizadas nos cuidados a pessoa com síndrome metabólica submetida a gastrectomia. Métodos: Pesquisa descritiva do tipo intervenção no cuidado a pessoa com síndrome metabólica submetida à gastrectomia, acompanhada pelo serviço de Enfermagem, no período de 2016 a 2018, em uma Unidade Básica de Saúde no interior da Bahia. Os dados foram obtidos por meio de anamnese, exame físico e exames clinico-laboratoriais disponíveis no prontuário. Os dados foram armazenados em tabela única constando os dados antropométricos e os exames glicêmicos e lipídicos antes e após a cirurgia. Adotou-se como parâmetro avaliativo a análise clínica descritiva das evidências constatadas no exame físico e nos resultados dos exames laboratoriais, como parte da rotina profissional. Resultados: Traçou-se os seguintes diagnósticos: Ansiedade; Medo; Nutrição desequilibrada: mais que as necessidades corporais; conhecimento deficiente sobre a síndrome metabólica. No pós-operatório da gastrectomia traçou-se: risco de nutrição desequilibrada: menos que as necessidades corporais; risco de infecção; dor aguda e integridade da pele prejudicada. Conclusão: Após a cirurgia, houve redução dos índices que a classificava como portadora da Síndrome Metabólica. Os dados antropométricos e metabólicos demonstram que a paciente não tem mais a síndrome porque a obesidade, a alteração glicêmica e da pressão arterial foram revertidas e as medicações suspensas(AU)


Introducción: El síndrome metabólico constituye un factor de riesgo cardiovascular y las estrategias para enfrentarlo son esenciales para reducir la morbimortalidad de la población. Objetivo: Describir el proceso de enfermería en los cuidados a la persona con síndrome metabólico sometida a la gastrectomía. Métodos: Se trata de una investigación descriptiva de intervención en el cuidado a la persona con síndrome metabólico sometida a la gastrectomía, acompañada por el servicio de enfermería, en el período de 2016 a 2018, en una Unidad Básica de Salud en el interior de Bahía. Los datos se obtuvieron a través de anamnesis, examen físico y exámenes clínicos y de laboratorio disponibles en los registros médicos. Los datos se almacenaron en una sola tabla que contenía datos antropométricos y pruebas de glucemia y lípidos antes y después de la cirugía. El parámetro evaluativo fue el análisis clínico descriptivo de la evidencia encontrada en el examen físico y los resultados de las pruebas de laboratorio, como parte de la rutina profesional. Resultados: Fueron trazados los siguientes diagnósticos de enfermería: ansiedad; miedo; nutrición desequilibrada: más que las necesidades corporales; el conocimiento deficiente sobre el síndrome metabólico. En el postoperatorio de la gastrectomía fueron trazados: riesgo de nutrición desequilibrada: menos que las necesidades corporales; riesgo de infección; dolor agudo e integridad de la piel perjudicial. Conclusión: Después de la cirugía hubo una reducción en las tasas que la clasificaron como síndrome metabólico. Los datos antropométricos y metabólicos muestran que el paciente ya no tiene el síndrome porque la obesidad, la alteración de la glucosa en la sangre y la presión arterial se revirtieron y se suspendieron los medicamentos(AU)


Introduction: Metabolic syndrome constitutes the cardiovascular risk factors and the strategies for its confrontation are essential to reduce the morbimortality of the population. Objective: Identify nursing diagnoses and perform care for a person with metabolic syndrome undergoing gastrectomy. Methods: It is a descriptive study of type intervention in the care of the person with Metabolic Syndrome submitted to gastrectomy, accompanied by the Nursing service, from 2016 to 2018, in a Basic Health Unit in the interior of Bahia. Data were obtained through anamnesis, physical examination and clinical and laboratory exams available in the medical records. Data were stored in a single table containing anthropometric data and glycemic and lipid tests before and after surgery. The evaluative parameter was the descriptive clinical analysis of the evidence found in the physical examination and the results of laboratory tests, as part of the professional routine. The study was approved by the Research Ethics Committee under Opinion No. 2.850.239. Results: It were traced the Nursing diagnoses: Anxiety; Fear; Unbalanced nutrition: more than bodily needs; knowledge about the metabolic syndrome. In post-operative gastrectomy were traced: risk of unbalanced nutrition: less than the bodily needs; risk of infection; acute pain and impaired skin integrity. Conclusion: After surgery, there was a reduction in the rates that classified her as having Metabolic Syndrome. Anthropometric and metabolic data show that the patient no longer has the syndrome because obesity, glycemic alteration and blood pressure were reversed and medications were suspended(AU)


Subject(s)
Humans , Nursing Diagnosis/methods , Metabolic Syndrome/epidemiology , Gastrectomy/adverse effects , Nursing Process , Medical Records , Indicators of Morbidity and Mortality , Epidemiology, Descriptive
5.
ABCD arq. bras. cir. dig ; 33(4): e1553, 2020. tab, graf
Article in English | LILACS | ID: biblio-1152628

ABSTRACT

ABSTRACT Background: Gastroesophageal reflux (GER) is one of the most common indications for conversion of sleeve gastrectomy (LSG) to laparoscopic Roux-en-Y gastric bypass (LRYGBP). Objective evaluations are necessary in order to choose the best definitive treatment for these patients. Aim: To present and describe the findings of the objective studies for gastroesophageal reflux disease performed before LSG conversion to LRYGBP in order to support the indication for surgery. Method: Thirty-nine non-responder patients to proton pump inhibitors treatment after LSG were included in this prospective study. They did not present GER symptoms, esophagitis or hiatal hernia before LSG. Endoscopy, radiology, manometry, 24 h pH monitoring were performed. Results: The mean time of appearance of reflux symptoms was 26.8+24.08 months (8-71). Erosive esophagitis was found in 33/39 symptomatic patients (84.6%) and Barrett´s esophagus in five. (12.8%). Manometry and acid reflux test were performed in 38/39 patients. Defective lower esophageal sphincter function was observed independent the grade of esophagitis or Barrett´s esophagus. Pathologic acid reflux with elevated DeMeester´s scores and % of time pH<4 was detected in all these patients. more significant in those with severe esophagitis and Barrett´s esophagus. Radiologic sleeve abnormalities were observed in 35 patients, mainly cardia dilatation (n=18) and hiatal hernia (n=11). Middle gastric stricture was observed in only six patients. Conclusion: Patients with reflux symptoms and esophagitis or Barrett´s esophagus after SG present defective lower esophageal sphincter function and increased acid reflux. These conditions support the indication of conversion to LRYGBP.


RESUMO Racional: O refluxo gastroesofágico é uma das indicações mais comuns para a conversão da gastrectomia vertical (SG) em gastroplastia laparoscópica em Y-de-Roux (LRYGBP). Avaliações objetivas são necessárias para escolher o melhor tratamento definitivo para esses pacientes. Objetivo: Apresentar e descrever os achados objetivos da doença do refluxo gastroesofágico realizados antes da conversão do SG para o LRYGBP, a fim de apoiar a indicação cirúrgica. Método: Trinta e nove pacientes não respondedores ao tratamento com inibidores da bomba de prótons após SG foram incluídos neste estudo prospectivo. Eles não apresentavam sintomas de refluxo gastroesofágico, esofagite ou hérnia hiatal antes da SG. Endoscopia, radiologia, manometria, monitoramento de pH 24 horas foram realizados. Resultados: O tempo médio de aparecimento dos sintomas de refluxo foi de 26,8+24,08 meses (8-71). Esofagite erosiva foi encontrada em 33/39 pacientes sintomáticos (84,6%) e esôfago de Barrett em cinco (12,8%). A manometria e o teste de refluxo ácido foram realizados em 38/39 pacientes. A função alterada do esfíncter inferior do esôfago foi observada independentemente do grau de esofagite ou esôfago de Barrett. Em todos esses pacientes, foi detectado refluxo ácido patológico com escores elevados de DeMeester e % de tempo pH<4, mais significativo nos com esofagite grave e esôfago de Barrett. Anormalidades radiológicas SG foram observadas em 35 pacientes, principalmente dilatação da cárdia (n=18) e hérnia hiatal (n=11). Estenose gástrica foi observada em apenas seis pacientes . Conclusão: Pacientes com sintomas de refluxo e esofagite ou esôfago de Barrett após SG apresentam função do esfíncter esofágico inferior defeituosa e aumento do refluxo ácido. Esses sintomas e estudos objetivos apoiam a indicação de conversão para LRYGBP.


Subject(s)
Humans , Female , Adult , Middle Aged , Obesity, Morbid/surgery , Gastric Bypass/adverse effects , Gastroesophageal Reflux/etiology , Laparoscopy/adverse effects , Gastrectomy/adverse effects , Gastroesophageal Reflux/surgery , Prospective Studies , Gastrectomy/methods
6.
ABCD arq. bras. cir. dig ; 33(3): e1539, 2020. tab, graf
Article in English | LILACS | ID: biblio-1141904

ABSTRACT

ABSTRACT Background: Laparoscopic surgery has been gradually accepted as an option for the surgical treatment ofgastric cancer. There are still points that are controversial or situations that are eventually associated with intra-operative difficulties or postoperative complications. Aim: To establish the relationship between the difficulties during the execution of total gastrectomy and the occurrence of eventual postoperative complications. Method: The operative protocols and postoperative evolution of 74 patients operated for gastriccancer, who were subjected to laparoscopic total gastrectomy (inclusion criteria) were reviewed. The intraoperative difficulties recorded in the operative protocol and postoperative complications of a surgical nature wereanalyzed (inclusion criteria). Postoperative medical complications were excluded (exclusion criteria). For the discussion, an extensive bibliographical review was carried out. Results: Intra-operative difficulties or complications reported correspond to 33/74 and of these; 18 events (54.5%) were related to postoperative complications and six were absolutely unexpected. The more frequent were leaks of the anastomosis and leaks of the duodenal stump; however, other rare complications were observed. Seven were managed with conservative measures and 17 (22.9%) required surgical re-exploration, with a postoperative mortality of two patients (2.7%). Conclusion: We have learned that there are infrequent and unexpected complications; the treating team must be mindful of and, in front of suspicion of complications, anappropriate decision must be done which includes early re-exploration. Finally, after the experience reported, some complications should be avoided.


RESUMO Racional: A cirurgia laparoscópica tem sido gradualmente aceita como opção para o tratamento cirúrgico do câncer gástrico. Ainda existem pontos controversos ou situações eventualmente associadas a dificuldades intra-operatórias ou complicações pós-operatórias. Objetivo: Estabelecer a relação entre as dificuldades durante a execução da gastrectomia total e a ocorrência de eventuais complicações pós-operatórias. Método: Foram revisados ​​os protocolos operatórios e a evolução pós-operatória de 74 pacientes operados por câncer gástrico, submetidos à gastrectomia total laparoscópica (critérios de inclusão). Foram analisadas as dificuldades intraoperatórias registradas no protocolo operatório e as complicações pós-operatórias de natureza cirúrgica (critérios de inclusão). As complicações médicas pós-operatórias foram excluídas (critérios de exclusão). Para a discussão, foi realizada extensa revisão bibliográfica. Resultados: Dificuldades ou complicações intraoperatórias relatadas corresponderam a 33/74 e destas 18 (54,5%) foram relacionadas com complicações pós-operatórias e seis absolutamente inesperadas. As mais frequentes foram vazamentos da anastomose e do coto duodenal; no entretanto, outras complicações raras foram observadas. Sete foram tratados com medidas conservadoras e 17 (22,9%) necessitaram de re-exploração cirúrgica, com mortalidade pós-operatória de dois pacientes (2,7%). Conclusão: Aprendemos que existem complicações infrequentes e inesperadas; a equipe de tratamento deve estar atenta e diante da suspeita de complicação, decisão apropriada pode incluir uma nova exploração precoce. Finalmente, após a experiência relatada, algumas complicações devem ser evitadas.


Subject(s)
Humans , Postoperative Complications/epidemiology , Stomach Neoplasms/surgery , Laparoscopy/adverse effects , Gastrectomy/adverse effects , Anastomosis, Surgical , Retrospective Studies
7.
Rev. Col. Bras. Cir ; 47: e20202537, 2020. tab, graf
Article in English | LILACS | ID: biblio-1136572

ABSTRACT

ABSTRACT Objective: to analyze the effect of vertical gastrectomy on lipid profile and cardiometabolic risk in young women, preoperatively and 6 months after the operation. Methods: retrospective study, encompassing medical record reviews of women's charts, preoperatively and in six months after the operation. Data collection was performed in the second half of 2015, using a review protocol with questions on the clinical-laboratory profile, anthropometric and laboratory classification of dyslipidemias. Descriptive and inferential analysis were used to treat the variables, using measures of variance, association and linear regression. Results: we analyzed medical records of 114 women undergoing vertical gastrectomy, with a mean age of 33.82±10.92, and with complete high school education. There was a significant reduction of anthropometric data, as well as serum lipid values, six months after the surgical procedure. The coefficients of determination and the results of linear regression, showed that the reduction in serum triglyceride values and increase in high-density lipoprotein have a direct impact on the reduction of the cardiometabolic risk. Regarding the laboratory classification of dyslipidemias, it was observed that the majority presented a significant reduction at the six-month follow-up. Mixed hyperlipidemia showed no significant reduction. The categorized cardiometabolic risk showed a significant reduction in women at risk before vertical gastrectomy. Conclusion: at the six-month follow-up, vertical gastrectomy was effective in reducing the serum lipid profile and the cardiometabolic risk of young women when compared to the preoperative data. There was also a different improvement in the laboratory classification of dyslipidemias at the six-month follow-up after the surgical procedure.


RESUMO Objetivo: analisar o efeito da gastrectomia vertical no perfil lipídico e risco cardiometabólico em mulheres jovens, no pré-operatório e com seis meses de seguimento. Métodos: estudo retrospectivo, realizado a partir de consultas a prontuários de mulheres, no pré-operatório e com seis meses de seguimento. A coleta de dados foi realizada no segundo semestre de 2015, utilizando-se roteiro com questões sobre o perfil clínico-laboratorial, antropométrico e da classificação laboratorial das dislipidemias. Para tratamento das variáveis, foi utilizada análise descritiva e inferencial, por meio de medidas de variância, associação e regressão linear. Resultados: foram analisados prontuários de 114 mulheres submetidas a gastrectomia vertical, com idade média de 33,82±10,92 e ensino médio completo. Houve redução significativa da antropometria, como também dos valores séricos dos lipídios após seis meses de seguimento do procedimento cirúrgico. Os coeficientes de determinação, resultados da regressão linear, mostraram que a redução dos valores séricos dos triglicerídeos e o aumento da lipoproteína de alta densidade têm explicação direta na redução do risco cardiometabólico. Quanto à classificação laboratorial das dislipidemias, observou-se que a maioria apresentou redução significativa, no seguimento de seis meses. A hiperlipidemia mista não teve redução significativa. O risco cardiometabólico, categorizado, teve redução significativa em mulheres que apresentavam risco antes da gastrectomia vertical. Conclusão: no seguimento de seis meses, houve eficácia da gastrectomia vertical na redução dos valores séricos do perfil lipídico e do risco cardiometabólico de mulheres jovens, em relação ao período pré-operatório. A classificação laboratorial das dislipidemias também teve redução dos parâmetros, no seguimento de seis meses após o procedimento cirúrgico.


Subject(s)
Humans , Female , Obesity, Morbid/surgery , Gastrectomy/adverse effects , Lipids/blood , Cardiovascular Diseases , Weight Loss , Retrospective Studies
8.
ABCD arq. bras. cir. dig ; 33(2): e1513, 2020. tab, graf
Article in English | LILACS | ID: biblio-1130520

ABSTRACT

ABSTRACT Background: Extended vertical gastrectomy is a variation of the vertical gastrectomy technique requiring studies to elucidate safety in relation to gastroesophageal reflux. Aim: To analyze comparatively vertical gastrectomy (VG) and extended vertical gastrectomy (EVG) in rats with obesity induced by cafeteria diet in relation to the presence of reflux esophagitis, weight loss and macroscopic changes related to the procedures. Methods: Thirty Wistar rats were randomized into three groups, and after the obesity induction period by means of a 28-day cafeteria diet, underwent a simulated surgery (CG), VG and VGA. The animals were followed up for 28 days in the post-operative period, and after euthanasia, the reflux esophagitis evaluation was histopathologically performed. Weight and macroscopy were the other variables; weight was measured weekly and the macroscopic evaluation was performed during euthanasia. Results: All animals presented some degree of inflammation and the presence of at least one inflammation criterion; however, there was no statistically significant difference in the analysis among the groups. In relation to weight loss, the animals in CG showed a gradual increase during the whole experiment, evolving to super-obesity at the end of the study, while the ones with VG and EVG had weight regain after the first post-operative period; however, a less marked regain compared to CG, both for VG and EVG. Conclusion: There is no difference in relation to reflux esophagitis VG and EVG, as well as macroscopic alterations, and both techniques have the ability to control the evolution of weight during postoperative period in relation to CG.


RESUMO Racional: A gastrectomia vertical ampliada é uma variação da técnica da gastrectomia vertical, necessitando de estudos a fim de elucidar a segurança em relação ao refluxo gastroesofágico. Objetivo: Analisar comparativamente gastrectomia vertical (GV) e gastrectomia vertical ampliada (GVA) em ratos com obesidade induzida por dieta cafeteria em relação à presença de esofagite de refluxo, perda de peso e alterações macroscópicas relacionadas aos procedimentos. Método: Trinta ratos Wistar foram randomizados em três grupos, e após período de indução de obesidade por meio de dieta cafeteria de 28 dias, foram submetidos a operação simulada (grupo controle GC), gastrectomia vertical (grupo GV) e gastrectomia vertical ampliada (grupo GVA). Os animais foram acompanhados por 28 dias no pós-operatório e, após a eutanásia, foi realizada a pesquisa de esofagite de refluxo através de avaliação histopatológica. Peso e avaliação macroscópica foram as outras variáveis de estudo, sendo o peso aferido semanalmente e a avaliação macroscópica no momento da eutanásia. Resultados: Todos os animais apresentaram algum grau de inflamação e a presença de ao menos um critério de inflamação, porém, não houve diferença estatisticamente significante na análise entre os grupos. Em relação à perda de peso, os animais do GC apresentaram aumento gradativo durante todo experimento evoluindo para super-obesidade ao término do estudo, enquanto os dos grupos GV e GVA tiveram reganho de peso após a primeira semana do pós-operatório, porém, reganho menos acentuado se comparável ao GC, tanto para GV quanto para GVA. Conclusões: Não há diferença em relação à esofagite de refluxo entre GV e GVA, bem como em relação às alterações macroscópicas. Ambas as técnicas têm capacidade de controlar a evolução do peso no pós-operatório em relação ao grupo controle.


Subject(s)
Humans , Animals , Rats , Gastroesophageal Reflux/etiology , Laparoscopy/adverse effects , Gastrectomy/methods , Obesity/surgery , Random Allocation , Rats, Wistar , Gastrectomy/adverse effects
9.
Rev. venez. cir ; 73(1): 10-13, 2020. ilus
Article in Spanish | LILACS, LIVECS | ID: biblio-1283939

ABSTRACT

La gastrectomía vertical laparoscópica es actualmente la cirugía bariátrica más empleada a nivel mundial. Aunque es un procedimiento seguro y efectivo pueden ocurrir complicaciones mayores. En el presente trabajo reportamos el caso de un infarto y absceso esplénico como una rara complicación de esta técnica, que requirió finalmente de esplenectomía como tratamiento definitivo. Caso clínico: Mujer de 22 años con obesidad grado I, a quien se le practicó gastrectomía vertical laparoscópica con buena evolución intrahospitalaria y egreso a las 48 horas. Al 4to día posoperatorio consultó por fiebre, dolor abdominal, taquipnea y taquicardia. Mediante tomografía computada de abdomen se diagnosticó infarto esplénico parcial. Recibió tratamiento médico con remisión inicial de los síntomas, los cuales reaparecieron a la 3era semana. Se reinició el tratamiento médico, esta vez sin respuesta, y con evolución al absceso esplénico. Se decidió esplenectomía como tratamiento definitivo logrando la recuperación completa de la paciente. Conclusión: El infarto esplénico es una complicación infrecuente de la gastrectomía vertical. Su tratamiento inicial es médico, reservando la esplenectomía para los casos que no responden(AU)


Laparoscopic sleeve gastrectomy is currently the most performed bariatric surgery worldwide. Although it is an effective and safe procedure major complications can occur. In the present manuscript we report a case of splenic infarct and abscess as a rare complication of laparoscopic sleeve gastrectomy, finally requiring a splenectomy as a definitive treatment. Case report: A 22 years old woman with grade I obesity underwent laparoscopic sleeve gastrectomy with good hospital evolution and 48 hours discharge. On the 4th postoperative day she return because fever, abdominal pain, tachypnea and tachycardia. By means of a computed tomography a splenic infarct was diagnosed. She received medical treatment with initial remission of symptoms, which reappear at the third week. Medical treatment was restarted, this time without success, and with progression to splenic abscess. We decided a splenectomy as definitive treatment achieving a complete patient recovery. Conclusion: Splenic infarction is a rare complication after sleeve gastrectomy. The treatment is non surgical, reserving the splenectomy for the non responded cases(AU)


Subject(s)
Humans , Female , Adult , Young Adult , Splenic Infarction/etiology , Laparoscopy/adverse effects , Bariatric Surgery/adverse effects , Gastrectomy/adverse effects , Splenectomy , Splenic Infarction/surgery , Splenic Infarction/diagnosis , Laparoscopy/methods , Bariatric Surgery/methods , Gastrectomy/methods , Obesity/surgery
10.
Rev. invest. clín ; 71(2): 98-105, Mar.-Apr. 2019. tab, graf
Article in English | LILACS | ID: biblio-1289675

ABSTRACT

Abstract Background Bursectomy consists of surgically removing the peritoneal lining covering the pancreas and the anterior plane of the transverse mesocolon during gastrectomy. However, there are little data to indicate whether bursectomy has a clinical benefit. Objective The objective of this study was to study the effect of bursectomy on complications, recurrence, and overall survival of patients with gastric cancer. Methods The publicly available literature published from January 2000 to July 2017 concerning gastrectomy with bursectomy and standard gastrectomy for gastric cancer was retrieved by searching the national and international online databases. Meta-analysis was performed after the data extraction process. Results Eight studies were finally included for a total of 1644 patients, of whom 644 underwent bursectomy and 1000 received standard gastrectomy without bursectomy. As shown by the meta-analysis results, there were no statistically significant differences in the presence of total post-operative complications (odds ratio [OR] = 1.06, 95% confidence interval [CI] [0.83-1.35], p = 0.63), overall recurrence (OR = 1.07, 95% CI [0.77-1.50], p = 0.68), 3-year overall survival (OR = 1.30, 95% CI [0.82-2.07], p = 0.26), and 5-year overall survival (OR = 0.91, 95% CI [0.66-1.27], p = 0.58). Conclusion Although application of bursectomy in radical gastrectomy did not increase post-operative complications, it offered no benefit to control tumor recurrence or improve overall survival.


Subject(s)
Humans , Postoperative Complications/epidemiology , Stomach Neoplasms/surgery , Gastrectomy/methods , Randomized Controlled Trials as Topic , Treatment Outcome , Gastrectomy/adverse effects
11.
Rev. chil. cir ; 71(1): 29-34, feb. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-985375

ABSTRACT

Resumen Introducción: La gastrectomía vertical (GV) y el by-pass gástrico (BPG) son los procedimientos más utilizados en el tratamiento de la obesidad. El objetivo de este trabajo es comparar ambas técnicas tanto en pérdida ponderal como en mejoría de las comorbilidades asociadas. Materiales y Método: Estudio observacional ambispectivo de los pacientes sometidos a BPG y GV desde enero de 2011 hasta diciembre de 2013. Se ha analizado la pérdida de peso y de IMC, la tasa de éxito, la reganancia de peso, el impacto en las comorbilidades asociadas y la morbimortalidad de ambas técnicas. Resultados: 172 pacientes fueron intervenidos (92 BPG y 80 GV). El BPG presenta mejores resultados en cuanto a pérdida de peso y mejoría de las comorbilidades. El grupo GV presenta mayor reganancia de peso. Ambos procedimientos presentan resultados similares en cuanto a morbimortalidad.


Introduction: Sleeve gastrectomy (SG) and gastric bypass (GBP) are the most commonly used procedures in the treatment of obesity. The objective of this paper is to compare these two techniques in regard to weight loss and improvement of the associated comorbidities. Material and Method: An ambispective observational study of patients undergoing GBP and SG from January 2011 to December 2013. Weight loss, BMI, success rate, weight regain, impact on associated comorbidities and morbimortality of both techniques were analysed. Results: 172 patients underwent operations (92 GBP and 80 SG). GBP had better results in regard to weight loss and improvement of comorbidities. The SG group had greater weight regain. The two procedures had similar results in regard to morbimortality.


Subject(s)
Humans , Male , Female , Gastric Bypass/adverse effects , Gastric Bypass/methods , Gastric Bypass/mortality , Gastrectomy/adverse effects , Gastrectomy/methods , Gastrectomy/mortality , Obesity, Morbid/surgery , Anastomosis, Roux-en-Y/methods , Weight Loss , Treatment Outcome , Perioperative Care
12.
ABCD arq. bras. cir. dig ; 32(4): e1473, 2019. tab, graf
Article in English | LILACS | ID: biblio-1054587

ABSTRACT

ABSTRACT Background: Gastrectomy is the main treatment for gastric and Siewert type II-III esophagogastric junction (EGJ) cancer. This surgery is associated with significant morbidity. Total morbidity rates vary across different studies and few have evaluated postoperative morbidity according to complication severity. Aim: To identify the predictors of severe postoperative morbidity. Methods: This was a retrospective cohort study from a prospective database. We included patients treated with gastrectomy for gastric or EGJ cancers between January 2012 and December 2016 at a single center. Severe morbidity was defined as Clavien-Dindo score ≥3. A multivariate analysis was performed to identify predictors of severe morbidity. Results: Two hundred and eighty-nine gastrectomies were performed (67% males, median age: 65 years). Tumor location was EGJ in 14%, upper third of the stomach in 30%, middle third in 26%, and lower third in 28%. In 196 (67%), a total gastrectomy was performed with a D2 lymph node dissection in 85%. Two hundred and eleven patients (79%) underwent an open gastrectomy. T status was T1 in 23% and T3/T4 in 68%. Postoperative mortality was 2.4% and morbidity rate was 41%. Severe morbidity was 11% and was mainly represented by esophagojejunostomy leak (2.4%), duodenal stump leak (2.1%), and respiratory complications (2%). On multivariate analysis, EGJ location and T3/T4 tumors were associated with a higher rate of severe postoperative morbidity. Conclusion: Severe postoperative morbidity after gastrectomy was 11%. Esophagogastric junction tumor location and T3/T4 status are risk factors for severe postoperative morbidity.


RESUMO Raciona l: A gastrectomia é o tratamento principal para o câncer de junção esofagogástrica (EGJ) e Siewert tipo II-III. Ela está associada à morbidade significativa. As taxas de morbidade total variam entre os diferentes estudos e poucos avaliaram a morbidade pós-operatória de acordo com a gravidade da complicação. Objetivo: Identificar os preditores de morbidade pós-operatória grave. Métodos: Este foi um estudo de coorte retrospectivo de um banco de dados prospectivo. Foram incluídos pacientes tratados com gastrectomia para câncer gástrico ou EGJ em um único centro. A morbidade severa foi definida como escore de Clavien-Dindo ≥3. Análise multivariada foi realizada para identificar preditores de morbidade grave. Resultados: Duzentos e oitenta e nove gastrectomias foram realizadas (67% homens, mediana de idade: 65 anos). A localização do tumor foi EGJ em 14%, o terço superior do estômago em 30%, o terço médio em 26% e o terço inferior em 28%. Em 196 (67%), foi realizada gastrectomia total com dissecção de linfonodos D2 em 85%. Duzentos e onze pacientes (79%) foram submetidos à gastrectomia aberta. O estado T foi T1 em 23% e T3/T4 em 68%. A mortalidade pós-operatória foi de 2,4% e a taxa de morbidade foi de 41%. A morbidade severa foi de 11% e foi representada principalmente por fístula esofagojejunal (2,4%), fístula duodenal (2,1%) e complicações respiratórias (2%). Na análise multivariada, a localização do EGJ e os tumores T3/T4 foram associados com maior morbidade pós-operatória grave. Conclusão: Morbidade pós-operatória severa após gastrectomia foi de 11%. A localização do tumor na junção esofagogástrica e o estado T3/T4 são fatores de risco para a morbidade pós-operatória grave.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Postoperative Complications/epidemiology , Stomach Neoplasms/surgery , Esophageal Neoplasms/surgery , Esophagogastric Junction/surgery , Gastrectomy/adverse effects , Retrospective Studies , Risk Factors , Cohort Studies
13.
ABCD arq. bras. cir. dig ; 32(1): e1413, 2019. tab, graf
Article in English | LILACS | ID: biblio-973378

ABSTRACT

ABSTRACT Background: Laparoscopic gastrectomy has numerous perioperative advantages, but the long-term survival of patients after this procedure has been less studied. Aim: To compare survival, oncologic and perioperative outcomes between completely laparoscopic vs. open gastrectomy for early gastric cancer. Methods: This study was retrospective, and our main outcomes were the overall and disease-specific 5-year survival, lymph node count and R0 resection rate. Our secondary outcome was postoperative morbidity. Results: Were included 116 patients (59% men, age 68 years, comorbidities 73%, BMI 25) who underwent 50 laparoscopic gastrectomies and 66 open gastrectomies. The demographic characteristics, tumour location, type of surgery, extent of lymph node dissection and stage did not significantly differ between groups. The overall complication rate was similar in both groups (40% vs. 28%, p=ns), and complications graded at least Clavien 2 (36% vs. 18%, p=0.03), respiratory (9% vs. 0%, p=0.03) and wound-abdominal wall complications (12% vs. 0%, p=0.009) were significantly lower after laparoscopic gastrectomy. The lymph node count (21 vs. 23 nodes; p=ns) and R0 resection rate (100% vs. 96%; p=ns) did not significantly differ between groups. The 5-year overall survival (84% vs. 87%, p=0.31) and disease-specific survival (93% vs. 98%, p=0.20) did not significantly differ between the laparoscopic and open gastrectomy groups. Conclusion: The results of this study support similar oncologic outcome and long-term survival for patients with early gastric cancer after laparoscopic gastrectomy and open gastrectomy. In addition, the laparoscopic approach is associated with less severe morbidity and a lower occurrence of respiratory and wound-abdominal wall complications.


RESUMO Racional: A gastrectomia laparoscópica tem numerosas vantagens perioperatórias, mas a sobrevivência em longo prazo após este procedimento tem sido menos estudada. Objetivo: Comparar resultados de sobrevivência, oncológica e perioperatória entre a gastrectomia completamente laparoscópica vs. aberta para câncer gástrico precoce. Método: Este estudo foi retrospectivo e os principais resultados foram a sobrevivência global e específica de cinco anos, contagem de linfonodos e taxa de ressecção R0. Resultado secundário foi a morbidade pós-operatória. Resultados: Foram incluídos 116 pacientes (59% homens, idade 68 anos, comorbidades 73%, IMC 25) que foram submetidos a 50 gastrectomias laparoscópicas e 66 gastrectomias abertas. As características demográficas, a localização do tumor, o tipo de operação, a extensão da dissecção dos linfonodos e do estágio não diferiram significativamente entre os grupos. A taxa geral de complicações foi semelhante em ambos os grupos (40% vs. 28%, p=ns) e complicações classificadas Clavien 2 (36% vs. 18%, p=0,03), respiratórias (9% vs. 0%, p=0,03) e as da parede abdominal (12% vs. 0%, p=0,009) foram significativamente menores após a gastrectomia laparoscópica. A contagem de linfonodos (21 contra 23, p=ns) e a taxa de ressecção R0 (100% vs. 96%; p=ns) não diferiram significativamente entre os grupos. A sobrevida global de cinco anos (84% vs. 87%, p=0,31) e a sobrevida específica (93% vs. 98%, p=0,20) não diferiram significativamente entre os grupos de gastrectomia laparoscópica e aberta. Conclusão: Estes resultados suportam resultados oncológicos similares e sobrevida em longo prazo para pacientes com câncer gástrico precoce após gastrectomia laparoscópica e gastrectomia aberta. Além disso, a abordagem laparoscópica está associada com morbidade menos grave e menor ocorrência de complicações respiratórias e da parede abdominal.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Stomach Neoplasms/surgery , Stomach Neoplasms/mortality , Laparoscopy/methods , Laparoscopy/mortality , Gastrectomy/methods , Gastrectomy/mortality , Postoperative Complications , Stomach Neoplasms/pathology , Time Factors , Chile , Survival Rate , Retrospective Studies , Treatment Outcome , Laparoscopy/adverse effects , Statistics, Nonparametric , Kaplan-Meier Estimate , Early Detection of Cancer , Perioperative Period , Gastrectomy/adverse effects , Lymph Node Excision/mortality , Neoplasm Staging
14.
Braz. j. med. biol. res ; 52(6): e8523, 2019. tab, graf
Article in English | LILACS | ID: biblio-1011583

ABSTRACT

This study aimed to observe the effects of lung-protective ventilation (LPV) on oxygenation index (OI) and postoperative pulmonary complications (PPCs) after laparoscopic radical gastrectomy in middle-aged and elderly patients. A total of 120 patients who were scheduled to undergo laparoscopic radical gastrectomy with an expected time of >3 h were randomly divided into conventional ventilation (CV group) with tidal volume (TV) of 10 mL/kg without positive end-expiratory pressure (PEEP), and lung-protective ventilation (PV group) with 7 mL/kg TV and personal level of PEEP with regular recruitment maneuver every 30 min. Measurements of OI, modified clinical pulmonary infection score (mCPIS), and PPCs were assessed during the perioperative period. Fifty-seven patients in the CV group and 58 in the PV group participated in the data analysis. Patients in the PV group showed better pulmonary dynamic compliance, OI, and peripheral capillary oxygen saturation during and after surgery. The mCPIS was significantly lower in the PV group than in the CV group after surgery. The incidence rate of PPCs was lower in the PV group than in the CV group and the difference was significant in patients whose ventilation time was longer than 6 h in both groups. LPV during laparoscopic radical gastrectomy significantly improved pulmonary oxygenation function and reduced postoperative mCPIS and the incidence of PPCs during the early period after surgery of middle-aged and elderly patients, especially patients whose mechanical ventilation time was longer than 6 h.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Postoperative Complications/prevention & control , Pulmonary Gas Exchange/physiology , Laparoscopy/methods , Gastrectomy/methods , Intraoperative Care/methods , Lung Diseases/prevention & control , Respiration, Artificial/methods , Double-Blind Method , Prospective Studies , Laparoscopy/adverse effects , Gastrectomy/adverse effects
15.
Rev. chil. cir ; 70(6): 598-603, dic. 2018. tab, graf
Article in Spanish | LILACS | ID: biblio-1042613

ABSTRACT

Varias publicaciones informan un aumento en la tasa de enfermedad por reflujo gastroesofágico (ERGE) después de la gastrectomía vertical tubular (GVT) o en manga a pesar que no existe aún consenso al respecto. El objetivo de este artículo es mostrar nuestra propia experiencia y de la literatura respecto a los aspectos clínicos de la enfermedad por ERGE después de la gastrectomía vertical tubular. Del análisis de nuestros resultados y de los datos de la literatura, los estudios que evalúan la prevalencia de la enfermedad de reflujo gastroesofágico posoperatorio muestran que la GVT puede provocar síntomas de ERGE de novo o empeoramiento de la ERGE preexistente.


Several publications report an increase in the rate of gastroesophageal reflux disease (GERD) after surgery, although there is still no consensus on this. The aim of this article is to show our own experience and literature regarding the clinical aspects of GERD disease after tubular vertical gastrectomy. From the analysis of our results and data from the literature, studies evaluating the prevalence of postoperative gastro-oesophageal reflux disease show that GVT can cause symptoms of de novo GERD or worsening of pre-existing GERD.


Subject(s)
Humans , Gastroesophageal Reflux/etiology , Gastrectomy/adverse effects , Gastrectomy/methods , Barrett Esophagus/etiology , Gastroesophageal Reflux/drug therapy , Esophagitis/etiology , Proton Pump Inhibitors/therapeutic use , Hernia, Hiatal/etiology
16.
Rev. chil. radiol ; 24(1): 40-43, mar. 2018. ilus
Article in Spanish | LILACS | ID: biblio-959572

ABSTRACT

Portograma aéreo o portograma de aire (PA), se define como la presencia de aire en el sistema venoso portomesentérico. Neumatosis intestinal (NI) se define como la presencia de aire en la pared intestinal, independiente de su causa o localización. La principal etiología de estas alteraciones es la isquemia intestinal aguda y en general, se consideran predictores de perforación intestinal y de mal pronóstico. Un pequeño grupo de pacientes con PA y/o NI pueden evolucionar sin complicaciones e incluso cursan sin manifestaciones clínicas. Presentamos el caso de una paciente con antecedente quirúrgico inmediato de gastrectomía total y reconstrucción en Y de Roux, que evidenció en tomografía computarizada (TC) de abdomen de control PA y NI, sin alteraciones clínicas significativas asociadas.


Hepatic portal venous gas (HPVG) is defined as the presence of air in the portal venous system. Pneumatosis intestinalis (PI) is defined as the presence of air within the bowel wall, regardless of its cause or location. Its main etiology is the intestinal ischemia and are generally considered predictors of intestinal perforation and wrong prognosis. A small group of patients with HPVG and PI may have a different clinical course, without complications and clinical manifestations. We report the case of a patient with immediate surgical history of total gastrectomy and Roux-en-Y reconstruction, which showed in computed tomography (CT) of the abdomen HPVG and PI, without associated clinically significant changes.


Subject(s)
Humans , Female , Middle Aged , Pneumatosis Cystoides Intestinalis/diagnostic imaging , Portal Vein/diagnostic imaging , Embolism, Air/diagnostic imaging , Pneumatosis Cystoides Intestinalis/etiology , Tomography, X-Ray Computed , Incidental Findings , Embolism, Air/etiology , Gastrectomy/adverse effects
17.
Rev. chil. cir ; 70(5): 480-487, 2018. tab, ilus
Article in Spanish | LILACS | ID: biblio-978019

ABSTRACT

Resumen La gastrectomía vertical tubular (GVT) o en manga ha sido validada como un procedimiento bariátrico efectivo para tratar pacientes con obesidad mórbida. Se han descrito modificaciones anatómicas y fisiopatológicas en la unión esofagogástrica que pueden estar relacionados con patogénesis de la enfermedad por reflujo gastroesofágico. En este artículo se muestran los resultados de nuestra propia experiencia y de la literatura respecto de los cambios en la función esofágica y gástrica, la prueba de reflujo ácido, los estudios endoscópicos y radiológicos en pacientes sometidos a GVT. Se concluye que la GVT puede presentar cambios anatómicos y fisiopatológicos que se asocian a la aparición de enfermedad por reflujo gastroesofágico.


Tubular vertical gastrectomy (GVT) or sleeve gastrectomy has been validated as an effective bariatric procedure to treat patients with morbid obesity. Anatomical and pathophysiological changes have been described in the esophagogastric junction that may be related to the pathogenesis of gastroesophageal reflux disease. This article shows the results of our own experience and the literature regarding changes in esophageal and gastric function, the acid reflux test, endoscopic and radiological studies in patients undergoing GVT. It is concluded that GVT can present anatomical and physiopathological changes that are associated with the appearance of gastroesophageal reflux disease.


Subject(s)
Humans , Gastroesophageal Reflux/etiology , Gastrectomy/adverse effects , Gastroesophageal Reflux/physiopathology , Gastrectomy/methods , Hydrogen-Ion Concentration , Manometry
18.
Rev. Col. Bras. Cir ; 45(6): e2016, 2018. tab
Article in Portuguese | LILACS | ID: biblio-976943

ABSTRACT

RESUMO Objetivo: comparar a prevalência das deficiências de micronutrientes nos pacientes submetidos à gastrectomia vertical (GV) e à derivação gástrica em Y de Roux (DGYR). Métodos: estudo comparativo de 576 pacientes submetidos à cirurgia bariátrica, 338 através de GV e 238 de DGYR e avaliados quanto às dosagens séricas de hemoglobina, ferro, ferritina, zinco e vitamina B12. Estas dosagens foram realizadas nos períodos pré-operatório e três, seis, 12 e 24 meses após a cirurgia, para análise e comparação das deficiências de micronutrientes entre as técnicas. Resultados: o grupo submetido à GV foi composto por 48 homens e 290 mulheres, com IMC médio de 39,4±2,6Kg/m2 e média de idade de 37,2±11 anos; o grupo submetido à DGYR foi composto por 77 homens e 161 mulheres, com IMC médio de 42,7±5,9Kg/m2 e média de idade de 41,9±11,1 anos. Após 24 meses, déficit de hemoglobina se fez presente em 24,4% dos pacientes submetidos à GV e 40% da DGYR (p=0,054); deficiência de ferro em 6,6% da GV e 15% da DGYR (p=0,127); déficit de ferritina em 17,8% da GV e 23,7% da DGYR (p=0,399); deficiência de zinco em 6,6% da GV e 30% da DGYR (p=0,002) e deficiência de B12 em 6,6% da GV e 8,7% da DGYR (p=0,844). Conclusão: pacientes submetidos à GV apresentaram níveis séricos de ferro e zinco superiores aos pacientes submetidos à DGYR, e a prevalência de déficit deste último micronutriente foi significativamente maior no grupo da DGYR.


ABSTRACT Objective: to compare the prevalence of micronutrient deficiencies in patients submitted to sleeve gastrectomy (SG) and Roux- en-Y gastric bypass (RYGB). Methods: this is a comparative study of 576 patients submitted to bariatric surgery, 338 to SG and 238 to RYGB, and evaluated for hemoglobin, iron, ferritin, zinc and vitamin B12 serum levels. We performed these dosages in the preoperative period and at three, six, 12 and 24 months after surgery, for analysis and comparison of micronutrient deficiencies among the techniques. Results: the SG group consisted of 48 men and 290 women, with a mean BMI of 39.4±2.6kg/m2, and a mean of age of 37.2±11 years; the group RYGB consisted of 77 men and 161 women, with mean BMI 42.7±5.9kg/m2, and a mean age of 41.9±11.1 years. After 24 months, hemoglobin deficiency was present in 24.4% of the patients submitted to SG and in 40% of the RYGB individuals (p=0.054); iron deficiency was present in 6,6% of SG patients and in 15% of RYGB ones (p=0.127); ferritin deficiency occurred in 17.8% of the SG group and in 23.7% of RYGB one (p=0.399); the Zinc deficiency incidence was 6.6% in SG and 30% in RYGB (p=0.002); and B12 deficiency took place in 6.6% the SG patients and in 8.7% of RYGB ones (p=0.844). Conclusion: patients undergoing SG had serum levels of iron and zinc superior to the ones undergoing RYGB, the prevalence of the latter micronutrient deficit being significantly higher in the RYGB group.


Subject(s)
Humans , Male , Female , Adult , Obesity, Morbid/surgery , Gastric Bypass/adverse effects , Micronutrients/deficiency , Malnutrition/etiology , Gastrectomy/adverse effects , Postoperative Period , Brazil/epidemiology , Hemoglobins/analysis , Hemoglobins/deficiency , Prevalence , Micronutrients/blood , Malnutrition/epidemiology , Preoperative Period , Gastrectomy/methods , Middle Aged
19.
Rev. cuba. cir ; 56(4): 1-11, oct.-dic. 2017. ilus
Article in Spanish | LILACS | ID: biblio-901001

ABSTRACT

Se presenta el caso de un paciente masculino de 73 años de edad operado por adenocarcinoma del antro gástrico. Se practicó gastrectomía subtotal distal más linfadenectomía D2. Durante el examen anatomopatológico de la pieza quirúrgica se encontró otro tumor pequeño en el espesor de la pared del antro cubierto por mucosa normal, separado del adenocarcinoma. El análisis histológico confirmó otra neoplasia incidental sincrónica, un tumor del estroma gastrointestinal de tipo fusiforme, positivo para el marcador tumoral CD117. El objetivo del trabajo es presentar esta asociación tumoral sincrónica, revisar sus características y las teorías etiopatogénicas actuales de esta condición sincrónica según la literatura especializada(AU)


A case is presented of a 73-year-old male patient who was operated for a gastric adenocarcinoma of the antrum. A distal subtotal gastrectomy plus D2 lymphadenectomy were practiced. During the anatomic and pathologic examination of the surgical piece, a second tiny tumor was found in the wall of the antrum and that was covered with a normal mucosa separated from the adenocarcinoma. The histologic examination confirmed another synchronous incidental neoplasm, a spindle-cell gastrointestinal stromal tumor, positive for the tumor marker CD117. This paper is aimed at presenting synchronous tumor entity, to review its characteristics and the current etiologic and pathogenic theories of this synchronic condition according to the specialized literature(AU)


Subject(s)
Humans , Male , Aged , Adenocarcinoma/diagnostic imaging , Gastrointestinal Neoplasms/etiology , Gastrointestinal Stromal Tumors/surgery , Gastrectomy/adverse effects
20.
Rev. chil. cir ; 69(5): 365-370, oct. 2017. tab, graf
Article in Spanish | LILACS | ID: biblio-899618

ABSTRACT

Resumen Introducción: La técnica de elección para la reconstrucción del tránsito intestinal después de una gastrectomía total es la esófago-yeyuno anastomosis en Y de Roux, la cual evita el reflujo de jugo digestivo alcalino. El objetivo del presente estudio es el de analizar la motilidad del esófago y del asa de yeyuno en pacientes operados con gastrectomía total por cáncer gástrico. Pacientes y método: Se estudió prospectivamente una muestra de 17 pacientes intervenidos mediante gastrectomía total 5 años atrás. En todos ellos se realizaron manometrías esofágicas de alta resolución incluyendo los primeros 7 cm del asa de yeyuno. Resultados: Los resultados de la manometría demostraron motilidad esofágica normal a excepción de la presión máxima intrabolo, la cual se encontraba aumentada en todos los pacientes. La motilidad del asa de yeyuno fue desordenada e inefectiva. Conclusiones: La motilidad del cuerpo esofágico es normal 5 años después de la gastrectomía total. Sin embargo, la presión intrabolo máxima se encuentra aumentada; la causa más probable de este hecho estaría constituida por el asa de yeyuno, que ejerce resistencia al paso del bolo debido a que presenta una actividad motora desordenada y poco propulsiva. El impacto clínico de este hecho es, sin embargo, poco importante.


Abstract Introduction: The most preferred technique to reconstruct the intestinal transit after total gastrectomy for gastric cancer is the Roux-en-Y esophagus-gastrostomy which prevents the reflux of alkaline intestinal juice. The purpose of this study was to analyze the esophageal motility and the motility of the jejunal loop in patients subjected to total gastrectomy. Patients and method: A prospective sample of 17 total gastrectomy patients operated on 5 years before was studied using high resolution esophageal manometry including the first 7 cm of the jejunal loop. Results: Manometry results showed normal esophageal body motility with the exception of the maximum intrabolus pressure that was elevated in all patients. The jejunal loop motility was disordered and ineffective. Conclusions: Esophageal body motility was normal 5 years after the surgical procedure. However, maximum intrabolus pressure was elevated and the most plausible reason would be the jejunal loop that exerts resistance to the bolus passage due to its ineffective motility. However, this fact does not have a significant clinical impact.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Anastomosis, Roux-en-Y/methods , Esophagus/physiology , Gastrectomy/methods , Jejunum/physiology , Manometry/methods , Postoperative Period , Stomach Neoplasms/surgery , Anastomosis, Roux-en-Y/adverse effects , Gastroesophageal Reflux/prevention & control , Prospective Studies , Treatment Outcome , Gastrectomy/adverse effects
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