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1.
Braz. j. biol ; 83: e250296, 2023. tab, graf
Article in English | MEDLINE, LILACS, VETINDEX | ID: biblio-1339385

ABSTRACT

Abstract The current study aimed to determine the effects of different levels of Zingiber officinale as a herbal feed additive on growth performance, carcass characteristic, serum biochemistry, total bacterial count (TBC), gut morphology, and immunological parameters of broilers. A total of 1500, day-old broiler chicks (Hubbard) were equally accredited to five treatment groups, each with six replicates (50 birds/replicate). Five experimental diets were prepared using basal diet i.e. with antibiotics positive control (PC), 3 g/kg ginger (group A), 6 g/kg ginger (group B), 9 g/kg ginger (group C) and without antibiotics negative control (NC). Group A and C showed significantly (p<0.05) higher feed intake (FI) as compared to other groups. Group C showed significantly (p<0.05) lower Total bacterial count (TBC) followed by group B as compared to NC. Carcass characteristics showed non-significant effects among different treatments. Mean villi length and width were significantly (p <0.05) higher in all ginger supplemented groups as compared to the control groups. Blood serum parameters including cholesterol, triglycerides, and low-density lipoproteins (LDL) were significantly (p<0.05) lower in groups B and C in comparison with the control groups. Whereas high-density lipoproteins (HDL) was significantly higher in group B as compared to the others. In conclusion, ginger supplementation @0.6% in the basal diet significantly improved growth performance and gut morphometry of broilers. It also showed a positive impact on cholesterol, triglycerides and gut microbes. Therefore, ginger could be a better substitute for antibiotic growth promoters.


Resumo O presente estudo teve como objetivo determinar os efeitos de diferentes níveis de Zingiber officinale como aditivo à base de plantas medicinais sobre o desempenho de crescimento, características da carcaça, bioquímica sérica, contagem bacteriana total (CBT), morfologia intestinal e parâmetros imunológicos de frangos de corte. Um total de 1.500 pintos de corte de um dia de idade (Hubbard) foram igualmente credenciados em cinco grupos de tratamento, cada um com seis repetições (50 aves/repetição). Cinco dietas experimentais foram preparadas usando dieta basal, ou seja, com controle positivo de antibióticos (PC), 3 g/kg de gengibre (grupo A), 6 g/kg de gengibre (grupo B), 9 g/kg de gengibre (grupo C) e sem controle negativo de antibióticos (NC). Os grupos A e C apresentaram consumo de ração (FI) significativamente (p < 0,05) maior do que os outros grupos. O grupo C apresentou contagem bacteriana total (CBT) significativamente menor (p < 0,05) seguido pelo grupo B em comparação com o NC. As características da carcaça apresentaram efeitos não significativos entre os diferentes tratamentos. O comprimento e largura médios das vilosidades foram significativamente (p < 0,05) maiores em todos os grupos suplementados com gengibre em comparação com os grupos de controle. Os parâmetros séricos do sangue, incluindo colesterol, triglicerídeos e lipoproteínas de baixa densidade (LDL), foram significativamente (p < 0,05) menores nos grupos B e C em comparação com os grupos controle. Enquanto as lipoproteínas de alta densidade (HDL) foram significativamente maiores no grupo B em comparação com os outros. Em conclusão, a suplementação de gengibre a 0,6% na dieta basal melhorou significativamente o desempenho de crescimento e a morfometria intestinal de frangos de corte. Ele também mostrou um impacto positivo sobre o colesterol, triglicerídeos e micróbios intestinais. Portanto, o gengibre pode ser um substituto melhor para os promotores de crescimento com antibióticos.


Subject(s)
Animals , Ginger , Chickens , Dietary Supplements , Diet/veterinary , Animal Feed/analysis
2.
Aquichan ; 21(1): e2115, Abr. 8, 2021.
Article in English | LILACS, BDENF, COLNAL | ID: biblio-1283774

ABSTRACT

Objective: To analyze the effectiveness of ginger in the reduction of the glycemic, lipid and anthropometric levels in people with Type 2 Diabetes Mellitus. Materials and method: A double-blind pilot study of the randomized clinical trial type, conducted between October 2017 and January 2018. The inclusion criteria were as follows: individuals with type 2 diabetes, aged from 18 to 80 years old, using oral antidiabetic drugs, and with glycated hemoglobin values between 7 % and 10 %. The participants were randomized and allocated in two different groups. In the experimental group, the participants used 1.2 g of ginger and, in the control group, 1.2 g of placebo. The primary outcome was the reduction in blood glucose. The reduction in the lipid and anthropometric levels was the secondary outcome. The intervention lasted four weeks. Results: A total of 21 participants were included in the study. The use of 1.2 g of ginger resulted in noticeable reductions in the anthropometric and lipid levels in 30 days of follow-up, but it did not reduce the glycemic levels. Conclusions: In this study, it was shown that ginger capsules, in doses of 1.2 g a day, can help to reduce anthropometric measures and lipid levels in the population under study; however, it had no effect on the glycemic levels.


Objetivo: analizar la efectividad del jengibre en la reducción de los niveles glicémicos, lipídicos y antropométricos de personas con diabetes mellitus tipo 2. Materiales y método: estudio piloto, del tipo ensayo clínico aleatorizado, doble ciego, llevado a cabo entre octubre de 2017 y enero de 2018. Los criterios de inclusión fueron los siguientes: personas con diabetes tipo 2, de 18 a 80 años de edad, en uso de antidiabéticos orales y con valores de hemoglobina glicada entre 7 % y 10 %. Los participantes fueron aleatorizados y asignados en dos grupos distintos. En el grupo experimental, los participantes usaron 1,2 g de jengibre y, en el de control, 1,2 g de placebo. El resultado primario fue la reducción de la glicemia. La reducción de los niveles lipídicos y antropométricos fue el resultado secundario. La intervención duró cuatro semanas. Resultados: 21 participantes formaron parte del estudio. El uso de 1,2 g de jengibre evidenció perceptibles reducciones de los niveles antropométricos y lipídicos en 30 días de seguimiento, pero no se mostró suficiente para reducir los niveles glicémicos. Conclusiones: en el estudio se demostró que cápsulas de jengibre, en dosis de 1,2 g por día, pueden ayudar a reducir medidas antropométricas y niveles lipídicos en la población del estudio, sin embargo, sin efecto en los niveles glicémicos.


Objetivo: analisar a efetividade do gengibre na redução dos níveis glicêmicos, lipídicos e antropométricos de pessoas com diabetes mellitus tipo 2. Materiais e método: estudo-piloto, do tipo ensaio clínico randomizado, duplo-cego, realizado entre outubro de 2017 e janeiro de 2018. Os critérios de inclusão foram: pessoas com diabetes tipo 2, de 18 a 80 anos, em uso de antidiabéticos orais e com valores de hemoglobina glicada entre 7 % e 10 %. Os participantes foram randomizados e alocados em dois grupos distintos. No grupo experimental, os participantes usaram 1,2 g de gengibre e, no grupo controle, 1,2 g de placebo. O desfecho primário foi a redução da glicemia. A redução dos níveis lipídicos e antropométricos foi o desfecho secundário. A intervenção durou quatro semanas. Resultados: 21 participantes fizeram parte do estudo. O uso de 1,2 g de gengibre trouxe perceptíveis reduções dos níveis antropométricos e lipídicos em 30 dias de acompanhamento, mas não se mostrou suficiente para a redução dos níveis glicêmicos. Conclusões: neste estudo, mostrou-se que cápsulas de gengibre, em doses de 1,2 g por dia, podem ajudar a reduzir medidas antropométricas e níveis lipídicos na população estudada, no entanto sem efeito nos níveis glicêmicos.


Subject(s)
Primary Health Care , Complementary Therapies , Clinical Trial , Ginger , Diabetes Mellitus, Type 2
3.
Rev. Inst. Adolfo Lutz ; 80(Único): e37287, dez. 2021. tab, ilus
Article in Portuguese | ColecionaSUS, LILACS, ColecionaSUS, SES-SP, CONASS, SESSP-ACVSES, SESSP-IALPROD, SES-SP, SESSP-IALACERVO | ID: biblio-1367628

ABSTRACT

Especiarias são produtos constituídos de partes de espécies vegetais com importante valor alimentício e diversos benefícios para a saúde. O objetivo deste trabalho foi pesquisar adulterações na composição de cúrcuma (Curcuma longa Linnaeus), gengibre (Zingiber officinale Roscoe), noz-moscada (Myristica fragrans Houttuyn), páprica (Capsicum annuum Linnaeus), pimenta-do-reino (Piper nigrum Linnaeus) e colorífico (mistura de urucum, Bixa orellana Linnaeus, com fubá). Foram analisadas 180 amostras adquiridas em municípios do estado de São Paulo. A investigação dos elementos histológicos foi feita por microscopia óptica, a análise dos corantes por cromatografia em papel e a quantificação da bixina por cromatografia líquida de alta eficiência. Das amostras analisadas, 16,1% apresentaram elementos histológicos estranhos ao produto, sendo que nenhuma amostra apresentou corante orgânico artificial. A concentração de bixina nas amostras de colorífico variou entre 0,6 e 105,3 mg/100g, com média de 18,9 mg/100g e desvio padrão de 17,7 mg/100g. A avaliação microscópica revelou que a maioria das adulterações ocorre pela adição de amido de Zea mays. O colorífico não apresentou adulterações, porém foi constatada a necessidade de uma padronização da concentração de bixina. Este estudo demonstrou a necessidade da intensificação do monitoramento de adulterações em especiarias para que a comercialização de alimentos fidedignos seja garantida. (AU)


Spices are products made up of parts of plant species, with important nutritional value and many health benefits. The aim of this work was to evaluate adulterations in turmeric (Curcuma longa Linnaeus), ginger (Zingiber officinale Roscoe), nutmeg (Myristica fragrans Houttuyn), paprika (Capsicum annuum Linnaeus), black pepper (Piper nigrumLinnaeus) and colorific (mixture containing Bixa orellana with cornmeal). A total of 180 samples purchased in the municipalities of the state of São Paulo were analyzed. The investigation of the histological elements was performed by optical microscopy, the analysis of the dyes was carried out using paper chromatography and the quantification of the bixin was performance by high performance liquid chromatography. Of the 180 samples analyzed, 16.1% presented strange histological elements, classified as adulterations. Among the adulterated samples, none showed organic dye. Bixin analysis was carried out on colorific samples, ranging from 0.6 ­ 105.3 mg/100g, with an average of 18.9 mg/100g and standard deviation of 17.7 mg/100g, demonstrating the need to regulate the annatto extract concentration range added into the condiment. The evaluation demonstrated the necessity to monitor adulteration in spices, so that producers and merchants provide food with quality to the consumer. (AU)


Subject(s)
Brazil , Capsicum , Food Contamination , Chromatography , Spices , Ginger , Myristica , Piper nigrum , Curcuma , Colorant , Legislation, Food , Microscopy , Fraud
4.
Rev. Inst. Adolfo Lutz ; 80(Único): e37291, dez. 2021. tab, ilus, graf
Article in Portuguese | ColecionaSUS, LILACS, ColecionaSUS, SES-SP, CONASS, SESSP-ACVSES, SESSP-IALPROD, SES-SP, SESSP-IALACERVO | ID: biblio-1367543

ABSTRACT

O objetivo deste trabalho foi avaliar a presença de matérias estranhas em noz-moscada, (Myristica fragrans Houttuyn), cúrcuma (Curcuma longa Linnaeus), gengibre (Zingiber officinale Roscoe), colorífico (mistura de urucum [Bixa orellana Linnaeus] com fubá), pimenta-do-reino (Piper nigrum Linnaeus) e páprica (Capsicum annuum Linnaeus) conforme a legislação sanitária. Foram analisadas 180 amostras empregando os métodos preconizados pela AOAC International, de maio de 2018 a maio de 2020. A presença de ao menos uma matéria estranha foi observada em 80% das amostras. Pelos animais foram observados em todos os produtos e fragmentos de insetos foram encontrados na maioria das amostras. Ácaro, inseto inteiro, larva de inseto, bárbula e exúvia também foram encontrados, além de fibras sintéticas e fragmentos de microplásticos. Quanto à legislação, 47,8% das amostras estavam acima dos limites de tolerância, destas, 90,7% por conterem matérias estranhas indicativas de falhas na aplicação das boas práticas e 9,3% por matérias estranhas indicativas de risco à saúde. Os resultados obtidos denotam ineficiência da aplicação das medidas de boas práticas na cadeia produtiva e alertam para a intensificação da fiscalização direcionada ao cumprimento das normas sanitárias, além de provocarem a reflexão sobre a necessidade de alterações na legislação referente às matérias estranhas. (AU)


The aim of this work was to evaluate the presence of foreign matter in nutmeg, (Myristica fragrans Houttuyn), turmeric (Curcuma longa Linnaeus), ginger (Zingiber officinale Roscoe), colorific (mixture of annatto [Bixa orellana Linnaeus] with cornmeal), black pepper (Piper nigrum Linnaeus) and paprika (Capsicum annuum Linnaeus) according to the health legislation. A total of 180 samples were analyzed using the methods recommended by AOAC International, from May 2018 to May 2020. The presence of at least one foreign matter was observed in 80% of the samples. Animal's hairs were observed in all the evaluated products and insect's fragments were found in the most of the samples. Mites, whole insects, insect larvae, barbules and exuvia were also found, as wellas synthetic fibers and microplastic fragments. About legislation, 47.8% of the samples were above the tolerance limits, of these, 90.7% for containing foreign matters indicating failure of good practices and 9.3% for foreign matters indicating health risk. The results obtained show inefficiency in the application of good practice measures in production chain and advertise for the intensification of inspection directed to fulfillment of sanitary norms, besides provoking the reflection on the necessity of alterations in the legislation about foreign matter in foods. (AU)


Subject(s)
Brazil , Food Quality , Spices , Ginger , Myristica , Piper nigrum , Curcuma , Colorant , Legislation, Food , Microscopy
5.
Article in Chinese | WPRIM | ID: wpr-877603

ABSTRACT

OBJECTIVE@#To observe the effect of ginger-separated moxibustion on fatigue state and intestinal flora in patients with chronic fatigue syndrome (CFS).@*METHODS@#A total of 62 patients with CFS were randomly divided into an observation group (31 cases, 3 cases dropped off) and a control group (31 cases, 2 cases dropped off). The patients in the control group were treated with normal diet and moderate exercise; on the basis of the control group, the patients in the observation group were treated with ginger-separated moxibustion at Zhongwan (CV 12), Shenque (CV 8) and Guanyuan (CV 4), 30 min each time, once every other day, three times a week. Both groups were intervened for 4 weeks. Before and after treatment, the fatigue scale-14 (FS-14) was used to observe the improvement of fatigue state, and 16S rRNA detection technology was used to detect the distribution of intestinal flora.@*RESULTS@#Compared before treatment, the FS-14 score was reduced after treatment in the observation group (@*CONCLUSION@#The ginger-separated moxibustion could significantly improve the fatigue state in CFS patients, which may be related to the regulation of intestinal flora structure and the repair of intestinal barrier.


Subject(s)
Acupuncture Points , Fatigue Syndrome, Chronic/therapy , Gastrointestinal Microbiome , Ginger , Humans , Moxibustion , RNA, Ribosomal, 16S
6.
Biosci. j. (Online) ; 36(3): 783-791, 01-05-2020. graf
Article in English | LILACS | ID: biblio-1146967

ABSTRACT

In order to achieve good yields and profitability from ginger crops, the water supply must be adequate. However, there are few studies available which have evaluated the adequate water supply to this vegetable. The objective of this study was to evaluate the effect of different irrigation depths on the development and productivity of ginger plants. The research was conducted at the "Sítio Schmidt" farm located in the municipality of Santa Maria de Jetibá, in the central mountainous region of Espírito Santo State, Brazil. The experimental design was a randomized block design with four replications, each experimental unit consisting of three rows at a spacing of 0.90 m and 0.10 m between plants of two meters extension, totaling 20 experimental units. The treatments consisted of application of five irrigation depths equivalent to: 50%, 75%, 100%, 125% and 150% of crop evapotranspiration (ETc). We evaluated the number of sprouts; average mass of export quality rhizome; the production of export, small and total rhizomes (t ha-1); and water use efficiency. The total water depth applied in the range 1100­1200 mm per cycle favors the development of ginger plants, providing the highest yields of total and export rhizomes, the greatest average mass of export quality rhizome and lowest production of small rhizomes.


Para que se alcance bons rendimentos e lucratividade com a cultura do gengibre o fornecimento de água deve ser adequado. Entretanto, ainda são poucos os trabalhos que avaliam o adequado fornecimento de água para esta hortaliça. Frente a isso, objetivou-se avaliar o efeito de diferentes lâminas de irrigação no desenvolvimento e na produtividade da cultura do gengibre. A pesquisa foi conduzida na propriedade "Sítio Schmidt" localizada no município de Santa Maria de Jetibá, região Central Serrana do Estado do Espírito Santo. O delineamento experimental utilizado foi o de blocos casualizados, com quatro repetições, sendo cada unidade experimental constituída por três fileiras em um espaçamento de 0,90 m e 0,10 m entre plantas de dois metros de extensão, totalizando 20 unidades experimentais. Os tratamentos consistiram na aplicação de cinco lâminas de irrigação, sendo elas: 50%, 75%, 100%, 125% e 150%. Foram avaliados o número de brotações; a massa média dos rizomas com padrão tipo exportação; as produtividades de rizomas tipo exportação, pequeno e total (t ha-1); e a eficiência do uso da água. A lâmina total aplicada na faixa de 1100-1200 mm por ciclo, ou seja, 75 a 100% da ETc favorece o desenvolvimento de plantas de gengibre, proporcionando maiores produtividades de rizoma total e tipo exportação, maior massa média de rizoma tipo exportação e menor produção de rizomas pequenos.


Subject(s)
Evapotranspiration , Water Use , Ginger , Dehydration , Horticulture
7.
Braz. arch. biol. technol ; 63: e20190213, 2020. tab, graf
Article in English | LILACS | ID: biblio-1132272

ABSTRACT

Abstract This study aims to find the best conditions for the extraction of Zingiber officinale essential oil using the supercritical fluid extraction (SFE), steam distillation (SD) and hydrodistillation (HD) techniques, regarding the maximum oil yield. For the HD technique is evaluated the best ratio between plant mass and water volume and for SFE and SD the pressure condition was investigated. Principal Component Analysis (PCA) was used to evaluate the similarity between the composition of the essential oil in different pressures and extraction methods. The experimental extraction curve was plotted and three different mathematical models were used to fit the data for SD and SFE methods, obtaining the relevant mass transfer parameters. The essential oil compounds were identified by gas chromatography coupled with mass spectrometry (GC-MS), being α-zingiberene the main component with different contents (from 11.9 to 28.9%). The best condition for the SFE was 100 bar, 40 °C (0.0508 goil/gplant) with 19.34% of α-zingiberene; for the SD, 3 bar (133 °C) (0.00616 goil/gplant) with 28.9% of α-zingiberene; and HD, the volume of 750 mL (0.006988 goil/gplant) with 15.70% of α-zingiberene, all measured on a dry basis.


Subject(s)
Oils, Volatile/isolation & purification , Ginger/chemistry , Distillation , Chromatography, Supercritical Fluid , Gas Chromatography-Mass Spectrometry , Models, Theoretical
8.
Rev. latinoam. enferm. (Online) ; 28: e3369, 2020. tab, graf
Article in English | LILACS, BDENF | ID: biblio-1139217

ABSTRACT

Objective: to evaluate the effectiveness of ginge (Zingiber officinale) in reducing blood sugar and lipid levels in people with type 2 diabetes. Method: a randomized and double-blind clinical trial conducted with people with type 2 diabetes in primary care facilities. The study included individuals aged between 20 and 80 years old, using oral antidiabetic drugs and with HbA1c levels between 6.0% and 10%. The participants were paired 1:1, allocated in two distinct groups, and randomized in blocks, based on their HbA1c levels. In the experimental group, the participants used 1.2g of ginger and, in the control group, 1.2g of placebo, daily for 90 days. The primary outcome was a reduction in fasting blood sugar and HbA1c, and the secondary outcome was a reduction in lipids and HOMA-IR. 103 individuals completed the study, 47 in the experimental group and 56 in the control group. Results: the participants in the experimental group showed a greater reduction in the blood glucose and total cholesterol values compared to the control group. Conclusion: the use of ginger can help in the treatment of people with diabetes, and data support the inclusion of this herbal drug in the clinical practice of nurses. RBR-2rt2wy


Objetivo: avaliar a efetividade do gengibre (Zingiber officinale) na redução de níveis glicêmicos e lipídicos de pessoas com diabetes tipo 2. Método: ensaio clínico randomizado, duplo cego, conduzido com pessoas com diabetes tipo 2, em unidades de atenção primária à saúde. Foram incluídos no estudo indivíduos com idade entre 20 e 80 anos, em uso de antidiabéticos orais e com valores de HbA1c entre 6,0% e 10%. Os participantes foram pareados de 1:1, alocados em dois grupos distintos e randomizados em blocos, com base nos valores de HbA1c. No grupo experimental os participantes usaram 1,2g de gengibre, e no grupo controle 1,2g de placebo, diariamente, durante 90 dias. Os desfechos primários foram a redução da glicemia venosa de jejum e HbA1c, e os secundários a redução dos lipídicos e HOMA-IR. 103 pessoas concluíram o estudo, encontrando-se 47 no grupo experimental e 56 no grupo controle. Resultados: os participantes do grupo experimental apresentaram melhor redução dos valores de glicemia e colesterol total, em comparação com o grupo controle. Conclusão: o uso do gengibre pode auxiliar o tratamento das pessoas com a diabetes, e os dados dão suporte para a inserção desse fitoterápico na prática clínica dos enfermeiros. RBR-2rt2wy


Objetivo: evaluar la eficacia del jengibre (Zingiber officinale) en la reducción de los niveles glucémicos y de lípidos en personas con diabetes tipo 2. Método: ensayo clínico aleatorizado y doble ciego, realizado con personas con diabetes tipo 2 en unidades de atención primaria de salud. Se incluyeron en el estudio individuos con edades comprendidas entre 20 y 80 años, que utilizaban antidiabéticos orales y con valores de HbA1c entre 6,0% y 10%. Los participantes fueron comparados de forma equitativa (1:1), asignados a dos grupos distintos y aleatorizados en bloques, basados en sus valores de HbA1c. En el grupo experimental, los participantes utilizaron 1,2 g de jengibre, y en el grupo de control 1,2 g de placebo, diariamente durante 90 días. Los resultados primarios fueron la reducción de glucemia venosa en ayunas y de HbA1c, y los resultados secundarios fueron la reducción de lípidos y del índice HOMA-IR. El estudio contó con la participación de 103 personas, 47 en el grupo experimental y 56 en el grupo de control. Resultados: los participantes del grupo experimental presentaron una mayor reducción en los valores de glucosa y colesterol total, en comparación con el grupo de control Conclusión: el uso del jengibre puede ayudar en el tratamiento de personas con diabetes, y los datos respaldan la introducción de este fitoterapéutico en la práctica clínica de los enfermeros. RBR-2rt2wy


Subject(s)
Humans , Adult , Middle Aged , Aged , Aged, 80 and over , Placebos , Therapeutics , Effectiveness , Blood Glucose , Double-Blind Method , Control Groups , Ginger , Diabetes Mellitus, Type 2 , Glucose , Hypoglycemic Agents , Lipids
9.
Chinese Acupuncture & Moxibustion ; (12): 1164-1168, 2020.
Article in Chinese | WPRIM | ID: wpr-877580

ABSTRACT

OBJECTIVE@#To observe the effect of ginger-partitioned moxibustion on digestive tract reaction, quality of life and white blood cell count after chemotherapy in advanced malignant bone tumors patients.@*METHODS@#A total of 64 patients were randomly divided into an observation group and a control group, 32 cases in each group. Both groups were treated with adriamycin combined with cisplatin (AP) chemotherapy. The patients in the control group were treated by tropisetron hydrochloride intravenous on preventing the vomiting 1 h before receiving chemotherapy. On the basis of the control group, the patients in the observation group were treated with ginger-partitioned moxibustion at Neiguan (PC 6), Zusanli (ST 36), Shenque (CV 8), and Zhongwan (CV 12) 2 h after chemotherapy, once a day, 30 min each time. The course of chemotherapy, ginger-partitioned moxibustion and tropisetron hydrochloride intravenous was 5 days. The digestive tract reaction rating, quality of life score and white blood cell count were compared 1 d before chemotherapy, 2 d after chemotherapy and 7 d after chemotherapy between the two groups.@*RESULTS@#The number of 0 grade in digestive tract reaction 2 d and 7 d after chemotherapy in the observation group was significantly higher than that in the control group (@*CONCLUSION@#Ginger-partitioned moxibustion can prevent and treat vomiting after chemotherapy in advanced malignant bone tumors, and improve the quality of life and white blood cell count of patients.


Subject(s)
Acupuncture Points , Bone Neoplasms/drug therapy , Ginger , Humans , Moxibustion , Quality of Life , Vomiting/etiology
10.
Article in Chinese | WPRIM | ID: wpr-828029

ABSTRACT

Coicis Semen is widely used as a raw material which can be used as both medicine and food among people. According to the ancient monographs on materia medica and relevant documents on the processing specifications in various provinces and cities, herba logical study on the historical evolution of the processing methods of Coicis Semen was conducted in this paper from the aspects of collecting and processing methods of Coicis Semen, the processing methods in the past dynasties and the nature, flavour and efficacy of Coicis Semen. The results showed that the processing methods of Coicis Semen recorded in monographs on materia medica mainly included stir-frying, glutinous rice stir-frying, salt processing(including salt cooking and salt stir-frying), stir-frying with the earth scraped from the wall facing east, and ginger juice stir-frying, etc. Among them, stir-frying, and stir-frying with the earth scraped from the wall facing east are still used nowadays. The bran stir-frying is the improved version of glutinous rice stir-frying in order to be adaptive to the modern-day situation and the needs of the present. In addition, the ancient shell removal and kernel keeping method are also included in the processing procedures in modern local processing specifications, which are combined with frying to form a new method named "Fazhi" processing( "Fazhi" means a processing method of multiple procedures). The 2015 edition of Chinese Pharmacopoeia records that Coicis Semen is helpful to clear dampness and promote diuresis, strengthen the spleen and prevent diarrhea, eliminate impediment, discharge pus, resolve toxin and a mass, etc., which are consistent with those contained in ancient monographs on materia medica. After the "Fazhi" processing, the cold nature of Coicis Semen has been removed and its nature,flavour and meridian tropism have been changed, so its application scopes expanded. The results of this study clearly traced the history of the collecting and proces-sing of Coicis Semen, summarized the nature, flavour and efficacy of Coicis Semen contained in both ancient and modern literature, and provided a historical basis for the standardization of the subsequent processing technology of Coicis Semen, the clinical application of various processed products, and the further development and utilization of medicinal materials.


Subject(s)
Coix , Cooking , Drugs, Chinese Herbal , Ginger , Materia Medica , Medicine, Chinese Traditional , Oryza
11.
Int. j. morphol ; 37(2): 438-447, June 2019. tab, graf
Article in English | LILACS | ID: biblio-1002240

ABSTRACT

Obesity is a modifiable risk factor for the development and progression of kidney disease. Obesity may harm kidneys in individuals without hypertension, diabetes, or pre-existing renal disease. Ginger, Zingiber officinale, has many beneficial pharmaceutical benefits. This study aimed to evaluate the Zingiber officinale protective effect against obesity complications which induced by high fat diet and caused renal dysfunctions. The study period was two months, and the experimental animals' groups were four, 80 Wistar rats were appropriated similarly 20 animals/group: control group; ginger extract group (GE); high-fat diet (HFD); and GE+HFD group. Body and fat weight, creatinine, leptin, TNF-α, total antioxidants, renal histopathological and ultrastructure were investigated. Rats in group of HFD showed a significant increase (P<0.05) in the body and fat weights, creatinine, leptin and TNF-α, and significant decrease (P<0.05) in total antioxidants (TAS). Ginger administration significantly showed the protective restoring the altered parameters. Furthermore, rats co-treated with ginger extract improved the histopathological and ultrastructural renal injury induced by obesity. The study concluded that the ginger extract used could suppress and decrease the renal damage induced by high-fat diet as it possesses potential medicinal values.


La obesidad es un factor de riesgo modificable para el desarrollo y la progresión de la enfermedad renal. La obesidad puede dañar los riñones en personas sin hipertensión, diabetes o enfermedad renal preexistente. El jengibre, Zingiber officinale, tiene muchos beneficios farmacéuticos. Este estudio tuvo como objetivo evaluar el efecto protector de Zingiber officinale en las complicaciones de la obesidad inducida por una dieta alta en grasas y las enfermedad renal. El período de estudio fue de dos meses, y los grupos de animales experimentales fueron cuatro, se asignaron 80 ratas Wistar de manera similar, 20 animales por grupo: grupo de control; grupo de extracto de jengibre (GE); dieta alta en grasas (DAG); y el grupo GE + DAG. Se evaluó el peso corporal y la grasa, creatinina, leptina, TNF-α, antioxidantes totales, histopatología renal y ultraestructura. Las ratas en el grupo de DAG mostraron un aumento significativo (P<0,05) en el peso corporal y de grasa, creatinina, leptina y TNF-a, y una disminución significativa (P<0,05) en los antioxidantes totales. La administración de jengibre mostró una protección significativa restaurando los parámetros alterados. Además, las ratas tratadas conjuntamente con extracto de jengibre mejoraron la lesión renal histopatológica y ultraestructural inducida por la obesidad. El estudio concluyó que el extracto de jengibre podría suprimir y disminuir el daño renal inducido por la dieta alta en grasas, ya que posee potenciales valores medicinales.


Subject(s)
Animals , Rats , Plant Extracts/pharmacology , Ginger/chemistry , Diet, High-Fat/adverse effects , Kidney Diseases/drug therapy , Obesity/complications , Body Weight , Tumor Necrosis Factor-alpha/analysis , Rats, Sprague-Dawley , Creatinine/analysis , Leptin/analysis , Microscopy, Electron, Transmission , Kidney/pathology , Kidney Diseases/pathology
12.
Rev. peru. med. integr ; 4(4): 121-126, 2019. graf, ilus
Article in Spanish | MTYCI, LILACS, MTYCI | ID: biblio-1145702

ABSTRACT

Objetivo. Evaluar la capacidad antioxidante in vitro del liofilizado de la pulpa y cáscara del rizoma de Zingiber officinale Roscoe (jengibre) mediante los ensayos DPPH, FRAP y TBARS. Materiales y métodos. Se separó la pulpa y la cáscara de los rizomas de Z. officinale, se preparó un macerado con solución hidroalcohólica (70:30 EtOH:H2O), y luego de rotaevaporar, se liofilizó. La capacidad antioxidante de los liofilizados se evaluó según porcentaje de inhibición del radical DPPH y el poder antioxidante de reducción férrica (FRAP), así como la capacidad de inhibir la peroxidación lipídica in vitro mediante el ensayo TBARS. Resultados. Los extractos liofilizados de la pulpa y cáscara evidenciaron moderada capacidad antioxidante, siendo similar según porcentaje de inhibición del radical DPPH (46,5 y 45,6% respectivamente). Sin embargo, mediante el ensayo FRAP la cáscara presentó una capacidad antioxidante de 31,09 µg/mL expresados como equivalentes de trolox (ET) en comparación a la pulpa (22,96 µg ET/mL). Además, solo el liofilizado de cáscara del rizoma de Z. officinale a bajas concentraciones (0,1, 0,2 y 0,3 mg/mL) es capaz de reducir significativamente (p < 0,01) la peroxidación lipídica in vitro. Conclusión. La cáscara del rizoma de Z. officinale posee mayor capacidad antioxidante en comparación con la pulpa según los ensayos FRAP y TBARS; sin embargo, la inhibición de radicales DPPH fue la misma tanto en la cáscara como en la pulpa.


Objective. To evaluate the in vitro antioxidant capacity of the freeze-dried pulp and peel of the rhizomes of Zingiber officinale Roscoe (ginger) using the DPPH, FRAP and TBARS assays. Materials and Methods. The pulp and peel were separated from the rhizomes of Z. officinale, then a macerate was prepared with a hydroalcoholic solution (70:30 EtOH: H2O), and after rotary evaporation, lyophilized. The antioxidant capacity of lyophilisates was evaluated according to the percentage of DPPH radical inhibition and the ferric reduction antioxidant power (FRAP), as well as the ability to inhibit lipid peroxidation in vitro using the TBARS assay. Results. Freeze-dried pulp and peel extracts showed moderate antioxidant capacity, being similar according to the percentage of DPPH radical inhibition (46.5% and 45.6% respectively). However, utilizing the FRAP assay, the peel presented an antioxidant capacity of 31.09 µg/mL expressed as Trolox Equivalents (ET) compared to the pulp (22.96 µg ET / mL). Also, only the freeze-dried peel of Z. officinale at low concentrations (0.1, 0.2 and 0.3 mg / mL) can significantly reduce p < 0.01 lipid peroxidation in vitro. Conclusion. The rhizome peel of Z. officinale has a higher antioxidant capacity compared to the pulp according to the FRAP and TBARS assays, however; DPPH radical inhibition was the same in both the peel and pulp.


Subject(s)
Thiobarbituric Acid Reactive Substances , Ginger , Antioxidants , Plants, Medicinal , In Vitro Techniques , Plant Extracts , Freeze Drying , Medicine, Traditional
13.
Braz. arch. biol. technol ; 62: e19180579, 2019. tab, graf
Article in English | LILACS | ID: biblio-1055409

ABSTRACT

Abstract Ginger and white yam starches were investigated and compared with maize starch. Proximal composition, thermogravimetry, differential scanning calorimetry, microscopy, colourimetry, X-ray powder diffractometry and pasting profile were analysed. The unconventional starches presented higher protein and ash contents than the maize starch, that had the highest thermal stability. Higher gelatinisation temperatures were reported for ginger starch, and the enthalpy of the unconventional starches were similar. The maize starch presented the lowest gelatinisation values. For the corn starch the granules were polygonal and smaller than the unconventional starches, and oval shapes and larger diameters were found for the ginger and yam starches. The unconventional starches presented less brightness and a greater tendency to red and yellow. The maize and ginger starches had A-type diffraction patterns, while the white yam starch had a C-type pattern. The highest relative crystallinity was observed for the ginger starch and there were small differences between the yam and maize starches. Higher peak viscosity and final viscosity and lower pasting temperature were observed for the yam starch. Ginger starch showed the highest shear and stability of heating glue, so may be used in products processed under high temperatures; and yam starch can be used in acidic foods that require high viscosities.


Subject(s)
Ginger/chemistry , Colocasia/chemistry , Starch and Fecula , Thermogravimetry/instrumentation , Differential Thermal Analysis/instrumentation , Microscopy/instrumentation
14.
Article in English | WPRIM | ID: wpr-760672

ABSTRACT

OBJECTIVE: Dysmenorrhea is one of the most common problems for women, especially during their reproductive age. Various studies have examined the effects of vitamins D and E and ginger supplements. This study aimed to investigate the individual effects of each of these supplements on dysmenorrhea. METHODS: This single-blind clinical trial was conducted in 2016 on students aged 18 to 25 years who complained of mild to severe dysmenorrhea. The participants were randomly assigned into 4 groups: vitamin D, vitamin E, ginger, and placebo. The effects of the supplements on the severity of dysmenorrhea were evaluated in 2 successive cycles using the visual analog scale (VAS) and a questionnaire. RESULTS: Initially, 240 female students were enrolled in the study; thereafter, 40 students were excluded from the study owing to follow-up loss. The average VAS score for dysmenorrhea in the entire study population was 7.13±0.80 before the intervention; the mean VAS score after the first and second months of supplement use was 5.37±1.51 and 4.93±1.48, respectively. The highest reduction in pain severity was observed in the ginger group (F=74.54, P<0.001). CONCLUSION: Vitamin D, vitamin E, and ginger significantly reduced the severity of dysmenorrhea, with ginger having the most significant effect followed by vitamin D and vitamin E. Given the low risk of these supplements, more studies must be conducted on their use as opposed to analgesics.


Subject(s)
Analgesics , Dysmenorrhea , Female , Follow-Up Studies , Ginger , Humans , Menstrual Cycle , Visual Analog Scale , Vitamin D , Vitamin E , Vitamins
15.
Article in English | WPRIM | ID: wpr-719636

ABSTRACT

Ginger, one of worldwide consumed dietary spice, is not only famous as food supplements, but also believed to exert a variety of remarkable pharmacological activity as herbal remedies. In this study, a ginger constituent, 12-dehydrogingerdione (DHGD) was proven that has comparable anti-inflammatory activity with positive control 6-shogaol in inhibiting LPS-induced interleukin (IL)-6, tumor necrosis factor (TNF)-α, prostaglandin (PG) E₂, nitric oxide (NO), inducible NO synthase (iNOS) and cyclooxygenase (COX)-2, without interfering with COX-1 in cultured microglial cells. Subsequent mechanistic studies indicate that 12-DHGD may inhibit neuro-inflammation through suppressing the LPS-activated Akt/IKK/NF-κB pathway. Furthermore, 12-DHGD markedly promoted the activation of NF-E2-related factor (Nrf)-2 and heme oxygenase (HO)-1, and we demonstrated that the involvement of HO-1 on the production of pro-inflammatory mediators such as NO and TNF-α by using a HO-1 inhibitor, Zinc protoporphyrin (Znpp). These results indicate that 12-DHGD may protect against neuro-inflammation by inhibiting Akt/IKK/IκB/NF-κB pathway and promoting Nrf-2/HO-1 pathway.


Subject(s)
Dietary Supplements , Ginger , Heme Oxygenase (Decyclizing) , Interleukins , Microglia , Nitric Oxide , Nitric Oxide Synthase , Prostaglandin-Endoperoxide Synthases , Spices , Tumor Necrosis Factor-alpha , Zinc
16.
Fortaleza; s.n; jul. 2018. 151 p.
Thesis in Portuguese | LILACS, BDENF | ID: biblio-1253798

ABSTRACT

O controle glicêmico do Diabetes Mellitus constitui um desafio da prática clínica. Ademais, o diabetes predispõe a dislipidemia diabética. A fitoterapia constitui uma alternativa de tratamento coadjuvante para a redução dos níveis glicêmicos e lipêmicos nas pessoas com diabetes tipo 2. Objetivou-se avaliar a efetividade do gengibre (Zingiber officinale) na redução dos níveis glicêmicos e lipêmicos de pessoas com diabetes tipo 2. Ensaio clínico randomizado, duplo cego, controlado por placebo, realizado em nove Estratégias de Saúde da Família de Picos/Piauí. A amostra totalizou 103 participantes com DM tipo 2, que foram alocados aleatoriamente em blocos pareados por hemoglobina glicada e sexo, em grupo controle (n =56) e experimental (n = 47). A coleta de dados foi realizada de dezembro/2017 a maio/2018. No recrutamento, os participantes foram orientados em relação ao protocolo do estudo e avaliados quanto aos critérios de exclusão e à adesão ao tratamento farmacológico, além da coleta para os dados bioquímicos. No encontro subsequente coletou-se dados socioeconômicos, clínicos e antropométricos e iniciou-se a intervenção com duração de três meses, cujo acompanhamento foi mensal. O grupo experimental consumiu uma cápsula contendo 600 miligramas de gengibre extrato seco 0,1% duas vezes ao dia e grupo controle recebeu cápsulas idênticas ao gengibre contendo celulose microcristalina MC-102. Para as análises de dados utilizou-se o SPSS 22.0, o software R 3.3.1., e os testes U de Mann-Whitey, Wilcoxon, Qui-quadrado de Pearson e Exato de Fischer. O estudo foi aprovado pelo Comitê de Ética em Pesquisa da Universidade Estadual do Piauí (Parecer: 2.248.450) e registrado na Rede Brasileira de Ensaios Clínicos (TRIAL: U111-1202-1650). Os resultados apontam a prevalência de mulheres, o tempo de diagnóstico < 5 anos e presença de hipertensão arterial. A maioria dos participantes eram sedentários, tinham sobrepeso e níveis elevados de glicemia e lipídios. O gengibre reduziu significativamente a glicemia de jejum (p=0,001), o colesterol (p=0,010) e o LDL-C (p=0,018) em relação aos valores basais, no entanto, não houve redução significativa do grupo experimental em relação ao grupo controle para esses parâmetros (-29,55 ± 53,76 vs. -9,25 ± 48,44, p=0,13), (-11,62±30,5 vs. -8,09±75,32, p=0,884) e (-7,45±23,12 vs. 11,97±66,15, p=0,12), respectivamente. O tempo de diagnóstico apresentou associação significativa com a glicemia, a idade com glicemia, HDL-C, LDL-C e HOMA-IR e a circunferência da cintura com o HDL-C e HOMA-IR. Conclui-se que o gengibre pode ser considerado uma terapia coadjuvante para o diabetes tipo 2, visto que reduziu alguns parâmetros glicêmicos e lipêmicos. (AU)


Subject(s)
Blood Glucose , Cholesterol , Ginger , Diabetes Mellitus, Type 2
17.
Mundo saúde (Impr.) ; 42(2): 534-547, jun. 2018. ilus, tab, graf
Article in English, Portuguese | LILACS | ID: biblio-1000088

ABSTRACT

Anisakid nematode helminths have great importance in public health, with several reports of human infections causedby larvae of these parasites in several countries of the world. These parasites are common in freshwater and marine fish,with man as an accidental host. Contamination occurs when humans feed on raw fish in the form of sushi, sashimi, andceviche, which are infected by the larval stages of these nematodes. In Brazilian rivers there are records of these larvaein Astyanax altiparanae (lambaris) and Geophagus brasiliensis (pearl cichlid), which are species widely distributed in theNeotropical region, especially in Brazil. These diseases are little-known by Brazilian health professionals because theirfrequency is still low, mainly due to the population's low fish consumption and the difficulties medical professionals havein diagnosing them. The present study aimed to evaluate the larvicidal action of ginger essential oil (Zingiber officinale) onlarvae of Contracaecum sp. removed from the visceral cavity of pearl cichlid and lambaris collected from the lake at IngáPark, Maringá, PR, in the year 2016. Two hundred and thirty-four fish specimens were necropsied, and their larvae weretested to verify the larvicidal effect of ginger. Of these fish, 123 were parasitized, equivalent to 52.5%, of which 181 larvaewere collected, all from the coelomic cavity. Ginger essential oil proved to be a promising larvicide, promoting larvaldeath in vitro. This larvicidal action was observed at different times and concentrations, showing the efficacy of ginger oilin combating this zoonosis. It is suggested that new natural products be tested for this purpose, as the number of peoplewho consume raw fish in Brazil continues to increase


Os helmintos nematoides anisaquídeos possuem grande importância em saúde pública, havendo vários relatos deinfecções humanas causadas pelas larvas desses parasitos em vários países do mundo. Esses parasitas são comuns empeixes de água doce e marinhos, tendo o homem como hospedeiro acidental. A contaminação ocorre quando os sereshumanos se alimentam de peixes crus na forma de sushi, sashimi e ceviche, infectados pelos estados larvais dessesnematoides. Nos rios brasileiros há registros dessas larvas em Astyanax altiparanae (lambaris) e Geophagus brasiliensis(acará ou papa-terra), que são espécies amplamente distribuídas na região Neotropical, em especial no Brasil. Essasdoenças são pouco conhecidas pelos profissionais da saúde brasileiros, pois sua frequência ainda é pequena, devido aobaixo consumo de peixes pela população e às dificuldades no diagnóstico pela classe médica. O presente estudo tevecomo objetivo avaliar a ação larvicida do óleo essencial de gengibre (Zingiber officinale) em larvas de Contracaecumsp. retirados da cavidade visceral de acarás e lambaris, coletados no lago do Parque do Ingá, Maringá, PR no ano de2016. Nesse sentido, 234 espécimes de peixes foram necropsiados e suas larvas testadas para verificar o efeito larvicidado gengibre. Destes peixes, 123 estavam parasitados, equivalendo a 52,5%, dos quais coletou-se 181 larvas, todas nacavidade celomática. Essas substancias mostraram-se promissores larvicidas, promovendo a morte das larvas no teste invitro do óleo essencial do gengibre. Essa ação larvicida foi observada em tempos e concentrações diferentes, mostrandoa eficácia do óleo de gengibre no combate a essa zoonose. Sugere-se que novos produtos naturais sejam testados comesse objetivo, pois é crescente o aumento no número de pessoas que passaram a se alimentar de peixes crus no Brasil


Subject(s)
Humans , Zoonoses , Ginger , Fishes , Larvicides
18.
Biosci. j. (Online) ; 34(3): 727-743, mai/jun. 2018. tab, graf
Article in English | LILACS | ID: biblio-966987

ABSTRACT

Spices are natural plant products, have been used not only as flavoring and coloring agents, but also as food preservatives and folk medicines throughout the world for thousands of years. Many spices also have been recognized by having both digestive stimulant and carminative actions and also antimicrobial, anti-inflammatory, antimutagenic and anti-carcinogenic potential. Antioxidant and genotoxic potential of species commonly used in Brazil was evaluated. The antioxidant activity was evaluated using different methods, including DPPH radical scavenging activity, ferric reducing power (FRAP), iron ion chelating power, inhibition of lipid peroxidation (TBARS), NO radical scavenging, and oxidative hemolysis inhibition. Furthermore, the antigenotoxic activity was evaluated through mitotic index and chromosome aberration in Allium cepa roots. Quantification of total phenols and flavonoids carried out. The results with the Ocimum basilicum spices in the DPPH test showed activity (82.01%), FRAP (321.12 uM ET and iron chelating activity (94.18) and for the Cinnamomum zeylanicum spice in the TBARS test (18.52%) evaluated by different methods and mechanisms of inactivation of free radicals and according to the evaluation of genotoxicity by the Allium cepa test the spices do not present genotoxic effects.


As especiarias são produtos vegetais naturais, que foram utilizados não só como agentes aromatizantes e colorantes, mas também como conservantes de alimentos e medicamentos populares em todo o mundo há milhares de anos. Muitas especiarias também foram reconhecidas por ter estimulantes digestivos e ações carminativas e também potencial antimicrobiano, anti-inflamatório, antimutagênico e anticarcinogênico. O potencial antioxidante e genotóxico das espécies comumente utilizadas no Brasil foi avaliado. A atividade antioxidante foi avaliada utilizando diferentes métodos, incluindo a atividade de eliminação de radicais DPPH, poder de redução férrica (FRAP), poder quelante de íons de ferro, inibição da peroxidação lipídica (TBARS), eliminação de radicais NO e inibição da hemólise oxidativa. Além disso, a atividade antigenotóxica foi avaliada através do índice mitótico e aberração cromossômica nas raízes do Allium cepa. Quantificação de fenóis totais e flavonoides realizados. Os resultados mostraram que as especiarias (Cinnamomum zeylanicum, Origanum vulgare, Piper nigrum, Zingiber officinale e Ocimum basilicum) apresentaram atividade antioxidante avaliada por diferentes métodos e mecanismos de inativação de radicais livres e de acordo com a avaliação de genotoxicidade pelo teste Allium cepa as especiarias não apresentam efeitos genotóxicos.


Subject(s)
Spices , Cooking , Genotoxicity , Antioxidants , Cinnamomum zeylanicum , Ocimum basilicum , Ginger , Piper nigrum , Origanum
19.
Braz. dent. j ; 29(1): 93-98, Jan.-Feb. 2018. tab, graf
Article in English | LILACS | ID: biblio-888723

ABSTRACT

Abstract The aim of this study was to evaluate in vitro the influence of 20% glycolic ginger extract on the bond strength of glass-fiber post cemented with etch-and-rinse or self-etching resin cement. Forty-eight bovine roots were standardized (17±0.5 mm) and randomly divided into two groups, according to irrigant used during biomechanical preparation: NaOCl: 1% sodium hypochlorite and GEN: 20% glycolic ginger extract. Root canal was prepared and randomly assigned to one of two subgroups (n=12), according to luting protocol: self-etching (RelyX U200) and etch-and-rinse (RelyX ARC). After 48 h, the roots were sectioned perpendicularly (4 in cervical third and 3 in middle third) and submitted to push-out bond strength test (50 kgf load cell, 1.0 mm/min). Failure mode was analyzed in SEM and stereomicroscopy. Data were analyzed by three-way ANOVA and Tukey tests (p<0.05). ANOVA revealed that there were no significant differences between U200 (2.01±0.17)B and ARC (1.93±0.12)B in GEN group, and at the cervical third for both irrigants, 2.69±0.16A and 2.54±0.17A, respectively. Middle third showed lower bond strength than cervical third, regardless the irrigant. Overall, the cervical third regardless the irrigant employed and the association between NaOCl and ARC, presented better adhesive performance.


Resumo O objetivo deste estudo foi avaliar in vitro a influência do extrato de gengibre 20% na resistência adesiva de pinos de fibra de vidro cimentados com cimentos resinosos convencional ou autocondicionantes. Quarenta e oito raízes bovinas foram padronizadas (17±0.5mm) e aleatoriamente divididas em dois grupos (n=24), de acordo com o irrigante utilizado durante o preparo biomecânico: NaOCl: hipoclorito de sódio 1%; e GEN: extrato glicólico de gengibre 20%. Os canais radiculares foram preparados e aleatoriamente distribuídos em dois subgrupos (n=12), conforme o protocolo de cimentação: autocondicionante (RelyX U200) e convencional (RelyX ARC). Após 48 h, as raízes foram seccionadas perpendicularmente (4 no terço cervical e 3 no terço médio) e submetidas ao teste de resistência adesiva push-out (50 kgf carga, 1.0 mm/min). O modo de falha foi analisado em MEV e estereomicroscopia. Os dados foram analisados pelos testes ANOVA 3-fatores e Tukey (p<0.05). ANOVA mostrou que não houve diferenças significativas entre U200 (2.01±0.17)B e ARC (1.93±0.12)B no grupo GEN, e no terço cervical para ambos os irrigantes (2.69±0.16A and 2.54±0.17A, respectivamente). O terço médio apresentou menor resistência adesiva que o terço cervical, independente do irrigante. Em geral, o terço cervical, independentemente do irrigante empregado, e a associação entre NaOCl e ARC apresentaram melhores desempenhos adesivos.


Subject(s)
Animals , Cattle , Ginger/chemistry , Glass , Materials Testing , Plant Extracts/pharmacology , Post and Core Technique
20.
Arq. bras. med. vet. zootec. (Online) ; 70(1): 199-204, Jan.-Feb. 2018. tab
Article in English | LILACS, VETINDEX | ID: biblio-888095

ABSTRACT

This study was carried out to evaluate the effects of dietary essential oils of ginger (Zingiber officinale), black seed (Nigella sativa) and cone flower (Echinacea angustifolia) on the immune system of cultured rainbow trout, Oncorhynchus mykiss. A total of 360 fish were divided into 4 groups and 3 replicates each containing 30 fish. The fish were fed for 21 days with 1% of the herbal essential oils and with unsupplemented diet as the control group. Haematological and immune parameters including serum lysozyme, number of phagocytic bacteria, Hb, PCV, MCV, MCH, MCHC, number of RBC and WBC were studied. Treatments recorded enhancement in immune parameters compared to the control group. Significantly higher serum lysozyme level and phagocytic germs were detected in the groups fed black seed, ginger and cone flower (P<0.05). However, no significant difference was found in RBC, Hb, PCV, MCV, MCH and MCHC of fish fed the diets containing essential oils and the control group (P>0.05). The results of this study demonstrated that essential oils might strengthen the non-specific immunity of rainbow trout.(AU)


Avaliou-se a eficácia de uma dieta com semente preta (Nigella sativa), gengibre (Zingiber officinale) e Flor-de-cone (Echinacea angustifolia) sobre o sistema imunológico de truta arco-íris (Oncorhynchus mykiss) em cultivo. Um total de 360 peixes foram divididos em 4 grupos com 3 repetições cada, contendo 30 peixes. Os peixes foram alimentados por 21 dias com 1% de óleo essencial herbáceo e com dieta comercial não suplementada como controle. Parâmetros imunes e hematológicos incluindo soro lisozima, número de bactéria fagocítica, Hb, PCV, MCV, MCH, MCHC, número de RBC e WBC foram estudados. Os tratamentos registraram a melhoria em parâmetros imunes comparados ao grupo de controle. Foram detectadas concentrações de lisozima no soro e germes fagocíticos significativamente altos em grupos que receberam semente preta, gengibre e Flor-de-cone (P<0.05). Porém, não foi encontrada diferença significativa em RBC, Hb, PCV, MCV, MCH e MCHC nos peixes alimentados com dietas contendo óleos essenciais e no grupo de controle (P>0.05). Os resultados deste estudo demonstraram que óleos essenciais podem aumentar a imunidade não específica da truta arco-íris.(AU)


Subject(s)
/administration & dosage , Nigella sativa/adverse effects , Ginger/immunology , Nigella sativa/immunology
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