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1.
Rev. ADM ; 78(6): 309-313, nov.-dic. 2021.
Article in Spanish | LILACS | ID: biblio-1354275

ABSTRACT

Introducción: El SARS-CoV-2 afecta el sistema respiratorio en diferentes grados. La cavidad oral es el lugar más colonizado por bacterias, por lo tanto, al no tener una adecuada higiene pueden presentarse diferentes enfermedades secundarias, lo que ha causado alerta en el gremio odontológico, ya que puede contribuir a complicaciones posteriores en los pacientes. Material y métodos: El estudio fue conformado por 47 pacientes voluntarios recuperados de SARS-CoV-2, residentes de Montemorelos, Nuevo León, México, donde fueron atendidos en Bucalia Dent, consultorio dental. Después del consentimiento informado de cada paciente, se realizó una historia clínica para conocer los síntomas, enfermedades sistémicas, ausencia de dientes y nivel de inflamación gingival de acuerdo al índice de Loe y Silness. A continuación, se tomó una muestra de biofilm microbiano (placa dentobacteriana), la cual se suspendió en una solución buffer de fosfato, posteriormente fue llevada al Centro de Investigación y Desarrollo en Ciencias de la Salud (CIDICS), Monterrey, N.L, México. Se extrajo DNA y se purificó, después se realizó PCR para detectar los patógenos orales; la PCR se visualizó en gel de agarosa (1.5%) por tinción de bromuro de etidio. Resultados: Se detectó 80.85% Porphyromona gingivalis y 68.09% Fusobacterium nucleatum en pacientes recuperados de SARS-CoV-2; 23.4% presentaron inflamación leve de acuerdo al índice de Loe y Silness, 54.5% fueron masculinos y 45.5% femeninos. Por otro lado, 36.4% de los pacientes con inflamación leve tenían de cuatro a seis dientes ausentes. En estos pacientes se detectó 18.18% únicamente con Fusobacterium nucleatum y 27.27% sólo con Porphyromona gingivalis; el sexo masculino tuvo predisposición en 66.6% y el femenino en 33.33%. Se observó infección con los dos patógenos presentes en 45.45%; y 60% de estos pacientes fueron masculinos. Conclusiones: Los pacientes recuperados de SARSCoV- 2 analizados en esta investigación mostraron mala higiene oral y alta prevalencia de los patógenos mencionados altamente relacionados a inflamación gingival o enfermedad periodontal, lo que nos indica que es indispensable la intervención del odontólogo al finalizar el periodo de infección de cada paciente (AU)


Introduction: SARS-CoV-2 affects the respiratory system to different degrees. The oral cavity is a colonized place by bacterias, therefore, by not having good hygiene, different secondary diseases can occur; this has caused an alert in the dental industry, since it can contribute to later complications in patients. Material and methods: The study was conducted in 47 SARS-CoV-2 recovered volunteers from the Montemorelos city of the Nuevo León state, Mexico, who were attended at the Bucalia Dent dental clinic. An informed consent was obtained from each of the patients, then their clinical history was documented in order to know the symptoms, previous systemic diseases, absence of teeth and degree of gingival inflammation, as suggested by Loe and Silness. Subsequently, a dental plaque sample was taken from all patients, which was suspended in a phosphate buffered solution and shipped to The Center for Research and Development in Health Sciences (CIDICS), Monterrey, NL, Mexico for storage. DNA extraction and purification was performed and PCR was carried out for the oral pathogens detection. All PCR products were visualized on 1.5% agarose gel by ethidium bromide staining. Results: Porphyromona gingivalis and Fusobacterium nucleatum were detected in 80.85% and 68.09% of SARS-CoV-2 recovered patients, respectively. 23.4% showed mild inflammation based on the Loe and Silness criteria, 54.5% were male and 45.5% female. On the other hand, 36.4% of patients with mild inflammation had between 4 to 6 missing teeth. A single infection by Fusobacterium nucleatum was detected in 18.18% and by Porphyromona gingivalis in 27.27%; the male sex had a predisposition with 66.66% and 33.33% female; coinfection of both pathogens was observed in 45.45% where 60% were male. Conclusions: SARS-CoV-2 recovered patients show poor oral hygiene and a high prevalence of oral pathogens related to the development of inflammatory gingival or periodontal disease, this suggests the need for an odontological clinical intervention at the end of the course of infection or disease caused by SARS-CoV-2 (AU)


Subject(s)
Humans , Male , Female , Adult , Oral Hygiene , Fusobacterium nucleatum , Porphyromonas gingivalis , SARS-CoV-2 , DNA , Oral Hygiene Index , Periodontal Index , Polymerase Chain Reaction , Dental Plaque/microbiology , Electrophoresis, Agar Gel , Age and Sex Distribution , Gingivitis/epidemiology , Mexico
2.
Braz. j. oral sci ; 20: e219280, jan.-dez. 2021. ilus
Article in English | LILACS, BBO | ID: biblio-1254266

ABSTRACT

Aim: To evaluate the effect of manual (M), electric (E) and ultrasonic (US) toothbrushes on the removal of oral biofilm and control of gingivitis. Also, the roughness and tooth wear production were evaluated in vitro. Methods: For the in vitro analyses, thirty bovine dentin specimens were submitted to a 3-month brushing simulation (9 minutes) with the three types of toothbrushes (n = 10). Subsequently, a randomized controlled clinical trial was performed with 36 patients divided into 3 groups according to the toothbrushes used (n = 12). Gingival index, visible plaque index and the volume of crevicular fluid were evaluated at baseline and 3 months after the beginning of the toothbrush use. Furthermore, the performance of the biofilm removal per brushing cycle of 1 and 3 minutes with each toothbrush was made monthly until the end of the experiment. Results: The US group had the highest dentin wear. Clinically, the US group had a lower plaque index at 3 months than the M group. The M group also showed less biofilm removal efficiency from the second month of follow-up and more worn bristles at the end of the 3 month period than the E and US groups. Conclusion: The ultrasonic, electric and manual toothbrushes showed no differences in gingivitis control in the present study. The ultrasonic and electric toothbrushes had a more significant effect on biofilm removal than a manual toothbrush, but the ultrasonic toothbrush promoted greater dentin tissue wear


Subject(s)
Humans , Male , Female , Oral Hygiene , Toothbrushing , Gingivitis
3.
Medicentro (Villa Clara) ; 25(2): 291-296,
Article in Spanish | LILACS | ID: biblio-1279421

ABSTRACT

RESUMEN Los estudios poblacionales muestran que la gingivitis es frecuente en la niñez; esta afección es más prevalente en la adolescencia y tiende a estabilizarse en edades más avanzadas. Se realizó un estudio descriptivo de corte epidemiológico transversal, en una población de 313 escolares, comprendidos en las edades de 5 a 12 años, pertenecientes al internado «Marta Abreu de Estévez¼, de la ciudad de Santa Clara, de septiembre de 2017 a junio de 2018, para caracterizar su estado periodontal. Prevaleció la gingivitis leve y se estableció la relación ascendente entre higiene bucal y gravedad de la enfermedad periodontal.


ABSTRACT Population studies show that gingivitis is common in childhood; this condition is more prevalent in adolescence and tends to stabilize at older ages. A descriptive, cross-sectional and epidemiological study was carried out in a population of 313 school children aged 5 to 12 years, belonging to "Marta Abreu de Estévez" boarding school, in Santa Clara city, from September 2017 to June of 2018, in order to characterize their periodontal status. Mild gingivitis prevailed and an ascending relationship between oral hygiene and severity of periodontal disease was established.


Subject(s)
Oral Hygiene , Periodontal Diseases , Gingivitis
4.
Medicentro (Villa Clara) ; 25(2): 197-212, tab, graf
Article in Spanish | LILACS | ID: biblio-1279416

ABSTRACT

RESUMEN Introducción: hacer una transición hacia la meta de una población sana periodontal, con fortalecimiento en la entrega del componente promocional preventivo, es un reto para los profesionales de Estomatología. Objetivo: evaluar la efectividad de una estrategia de intervención educativa-curativa para la enfermedad periodontal inflamatoria crónica en adolescentes. Métodos: se realizó un estudio longitudinal prospectivo de intervención mediante un pre-experimento, de enero de 2018 a septiembre de 2019, en la escuela Secundaria Básica «13 de marzo¼, de Placetas, Villa Clara. La población de estudio estuvo constituida por 117 adolescentes del 7mo grado escolar y sus padres, así como los 16 profesores que trabajaron con ellos. Las variables del estudio fueron: la condición periodontal, el nivel de información sobre la enfermedad periodontal, la higiene bucal y la efectividad de la estrategia. Se utilizaron: la estadística descriptiva, fundamentalmente las frecuencias absolutas y porcientos, y la prueba de los rangos con signo de Wilcoxon como prueba no paramétrica. Resultados: el 69,2 % de los adolescentes presentaron gingivitis, y el 65,8% tenía un nivel de información insuficiente. La estrategia de intervención educativa-curativa de la enfermedad periodontal inflamatoria crónica constó de cuatro etapas: diagnóstica, planeación estratégica, implementación y evaluación, con un componente educativo (programa educativo) y otro curativo. La caracterizaron los objetivos a corto, mediano y largo plazo, y las acciones para dar cumplimiento a dichos objetivos. Conclusiones: la estrategia fue valorada por criterios de especialistas como adecuada, y se consideró efectiva después de su aplicación.


ABSTRACT Introduction: making a transition towards the goal of a healthy periodontal population, with strengthening in the delivery of the preventive promotional component is a challenge for dentistry professionals. Objective: to evaluate the effectiveness of an educational and curative intervention strategy for chronic inflammatory periodontal disease in adolescents. Methods: a prospective, longitudinal and intervention study was carried out through a pre-experiment at "13 de Marzo" Basic Secondary School in Placetas, Villa Clara from January 2018 to September 2019. The study population consisted of 117 adolescents from the 7th grade and their parents, as well as, 16 teachers who worked with them. Periodontal condition, level of information on periodontal disease, oral hygiene and effectiveness of the strategy were the variables studied. Descriptive statistics, mainly absolute frequencies and percentages, and Wilcoxon signed - rank test, as a non-parametric test were used. Results: 69.2% of the adolescents had gingivitis, and 65.8% had an insufficient level of information. The educational and curative intervention strategy for chronic inflammatory periodontal disease consisted of four stages: diagnosis, strategic planning, implementation and evaluation, with an educational component (educational program) and a curative one. It was characterized by short- , medium- and long-term objectives, as well as the actions to fulfill those objectives. Conclusions: the strategy was assessed by specialist criteria as adequate, and it was considered effective after its application.


Subject(s)
Local Health Strategies , Adolescent , Gingivitis
5.
Rev. odontol. UNESP (Online) ; 50: e20210045, 2021. tab, ilus
Article in English | LILACS, BBO | ID: biblio-1352135

ABSTRACT

Introduction Gingivitis is a gingival inflammation which can often be treated with oral hygiene such as brushing, flossing, and an antiseptic mouthwash. Objective The aim of this randomized clinical trial was to clinically evaluate the effectiveness of 0.12% chlorhexidine (CHX) solution as an anti-inflammatory agent and for reducing the presence of plaque and inflammation in young adults. Material and method Thirty patients with gingivitis aged 18 to 30 years with a probing depth ≤ 3 mm and a minimum of 20 teeth in the whole mouth were selected and evaluated at baseline and 30 days after treatment. Periodontal clinical parameters were verified: plaque index (PI), gingival index (GI), Simplified Oral Hygiene Index (OHI-S), Simplified Debris Index (DI-S), and Simplified Calculus Index (CI-S) Patients were then randomly allocated into two groups: CHX Group, received chlorhexidine 0.12% labeled as solution 1, and Placebo Group, received saline solution labeled as solution 2. Both groups were included in a hygiene program and received mouthwash. Result Statistically significant differences between CHX and Placebo groups were observed for the variables PI, GI, DI-S, CI-S, and OHI-S (p<0.05 - Paired T Test) after 30 days. The CHX group presented improved GI compared to Placebo at 30 days. Chlorhexidine 0.12% was efficient in the control of periodontium inflammation. Conclusion It can be concluded that chlorhexidine as a mouthwash is efficient in improving periodontal indices in young adults, but it is still controversial whether age can influence GI and OHI-S.


Introdução A gengivite é uma inflamação gengival que geralmente pode ser tratada com higiene oral, como escovação, uso do fio dental e um anti-séptico bucal. Objetivo O objetivo deste ensaio clínico randomizado foi avaliar clinicamente a eficácia da solução de clorexidina 0,12% (CHX) como um agente antiinflamatório e na redução da presença de placa e inflamação em adultos jovens. Material e método Trinta pacientes com gengivite com idade entre 18 e 30 anos com profundidade de sondagem ≤ 3 mm com mínimo de 20 dentes em toda a boca foram selecionados e avaliados no início do estudo e 30 dias após o tratamento. Foram verificados os parâmetros clínicos periodontais: índice de placa (IP), índice gengival (GI), Índice de Higiene Oral Simplificado (IHO-S), Índice de Debris Simplificado (DI-S) e Índice de Cálculo Simplificado (IC-S). A seguir, os pacientes foram alocados aleatoriamente em dois grupos: Grupo CHX, recebeu clorexidina 0,12% previamente identificada como solução 1 e grupo placebo, recebeu solução salina identificada como solução 2. Ambos os grupos foram incluídos em programa de higiene e receberam enxaguatório bucal. Resultado Diferença estatisticamente significante entre os grupos CHX e Placebo foi observada para as variáveis ​​PI, GI, DI-S, CI-S e OHI-S (p <0,05 - Teste T Pareado) após 30 dias. O grupo CHX melhorou a resposta ao GI em comparação ao placebo em 30 dias. Clorexidina 0,12% foi eficiente no controle da inflamação do periodonto. Conclusão Pode-se concluir que a eficácia da clorexidina como enxaguatório bucal na melhora dos índices periodontais foi confirmada em adultos jovens, mas ainda é controverso que a idade pode influenciar o IG e IHO-S.


Subject(s)
Humans , Adolescent , Adult , Oral Hygiene , Periodontitis , Placebos , Chlorhexidine , Oral Hygiene Index , Periodontal Index , Gingivitis , Mouthwashes , Adolescent , Adult
6.
Article in English | LILACS, BBO | ID: biblio-1287497

ABSTRACT

ABSTRACT Objective: To analyze periodontal comparison between Systemic Lupus Erythematosus (SLE) subject and healthy control. Material and Methods: This descriptive cross-sectional study included 122 subjects, 61 SLE patients and 61 healthy subjects who visited the Rheumatology Department, Dr. Saiful Anwar General Hospital, Malang, during 2017-2018. Clinical examination of SLE was using Mexican SLE Disease Activity Index and oral cavity conditions were assessed using the periodontal index, gingival index, calculus index, bleeding on probing, clinical attachment loss and mobility teeth. Results: The age of SLE patients ranged from 18-55 years old with the mean age of 29.50 ± 9.57 years old. Periodontitis was higher in SLE patients (88.5%) than healthy subjects (22.95%). In addition, periodontitis occurrence in SLE (2.66 ± 1.02) was significantly different (p<0.001) compared to healthy subjects (0.51 ± 0.81). Conclusion: This study found higher rates of periodontitis, gingivitis, bleeding on probing, clinical attachment loss, and mobility tooth among SLE patients compared to healthy subjects. Periodontitis was also found to be higher along with more severe SLE group.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Periodontal Diseases/pathology , Tooth Mobility , Periodontal Index , Connective Tissue Diseases , Lupus Erythematosus, Systemic/pathology , Periodontitis , Clinical Diagnosis , Dental Plaque Index , Oral Health , Epidemiology, Descriptive , Cross-Sectional Studies/methods , Data Interpretation, Statistical , Statistics, Nonparametric , Gingivitis , Indonesia/epidemiology
7.
Arq. odontol ; 57: 106-113, jan.-dez. 2021. tab
Article in Portuguese | LILACS, BBO | ID: biblio-1224424

ABSTRACT

Objetivo: Este estudo teve o objetivo de avaliar a associação entre doença periodontal e obesidade. Métodos: Foi realizada uma busca nas bases PubMed, SciELO e Bireme, sendo incluídos estudos relevantes relacionados ao tema para síntese deste trabalho. Resultados: Foram selecionados treze artigos para serem incluídos nessa revisão, sendo um ensaio clínico, uma meta-análise, dois estudos de coorte, dois caso-controle, cinco estudos transversais e duas revisões sistemáticas. Conclusão: Existe uma plausibilidade biológica entre a obesidade e a doença periodontal, porém não há um consenso na literatura sobre essa associação. Desta forma, são necessários mais estudos prospectivos, laboratoriais, de coorte e meta-análises que avaliem tal associação entre as doenças.


Aim: This study aimed to assess the association between periodontal disease and obesity. Methods: A search was performed in the PubMed, SciELO, and Bireme databases, including relevant studies related to the theme for the synthesis of this work. Results: Thirteen articles were selected to be included in this review, one clinical trial, one meta-analysis, two cohort studies, two case-control studies, five cross-sectional studies and two systematic reviews. Conclusion: There is a biological plausibility between obesity and periodontitis, but there is no consensus in the literature about this association. Thus, further prospective, laboratory, cohort, and meta-analysis studies are needed to assess such an association between diseases.


Subject(s)
Periodontal Diseases , Periodontitis , Metabolic Syndrome , Gingivitis , Obesity , Review
8.
Chinese Journal of Stomatology ; (12): 238-243, 2021.
Article in Chinese | WPRIM | ID: wpr-879315

ABSTRACT

Report of the fourth national oral health survey showed that the prevalence of gingivitis and periodontitis stayed at a high level in Chinese population and the periodontitis was the most common cause of tooth loss in Chinese adults. Therefore, the examination of periodontal health status, disease condition and risk assessment are particularly important. The Society of Periodontology of the Chinese Stomatological Association organized experts of related disciplines to formulate the standard of basic periodontal examination and evaluation during oral diagnosis and treatment, aiming to emphasize the necessity and importance of periodontal health and to improve dental clinicians' abilities in understanding, diagnosis and treatment planning of periodontal disease. As a national and professional standard, it will play an important and practically significant role in conservation of natural teeth and improvement of people's oral health in China.


Subject(s)
Adult , China , Diagnosis, Oral , Gingivitis , Humans , Periodontal Diseases/therapy , Reference Standards
9.
J. oral res. (Impresa) ; 9(6): 500-510, dic. 31, 2020. tab
Article in English | LILACS | ID: biblio-1178947

ABSTRACT

Objetive: Home oral care practices in patients undergoing orthodontic therapy are often ineffective in maintaining optimal plaque control. The aim of the present study was to assess the effectiveness of periodontal maintenance program in subjects with established gingivitis undergoing fixed orthodontic appliance therapy for one year. Material and Methods: Forty patients undergoing fixed orthodontic appliance therapy with established chronic gingivitis were recruited for the study. As a part of a periodontal maintenance program, a pre-validated structured questionnaire evaluating oral hygiene and periodontal health was administered at the baseline as well as at the end of the study. At the baseline Gingival Bleeding Index, Gingival Index, and Bonded Bracket Plaque Index scores were recorded, Scaling and polishing procedure was performed followed by a customised Oral Hygiene Advice (OHA) session was conducted for all the study subjects. Clinical indices were assessed and OHA was conducted at the 3rd, 6th, 9th, and 12th months of orthodontic treatment visits. Results: There was significant improvement in the clinical indices and awareness regarding oral hygiene and periodontal health level in the patients at the end of the 12th month. Conclusion: The periodontal maintenance program appeared to be effective in improving the periodontal health and awareness health awareness level about oral hygiene among patients undergoing fixed orthodontic therapy at the end of 12 months in our study population.


Objetivo: Las prácticas de cuidado bucal en el hogar en pacientes sometidos a terapia de ortodoncia suelen ser ineficaces para mantener un control óptimo de la placa. El objetivo del presente estudio fue evaluar la efectividad del programa de mantenimiento periodontal en sujetos con gingivitis establecida sometidos a terapia con aparatos de ortodoncia fijos durante un año. Material y Métodos: Se reclutó para el estudio a 40 pacientes sometidos a terapia con aparatos de ortodoncia fijos y con gingivitis crónica establecida. Como parte de un programa de mantenimiento periodontal, se administró un cuestionario estructurado pre-validado que evaluaba la higiene bucal y la salud periodontal al inicio y al final del estudio. En la línea de base, se registraron las puntuaciones del índice de sangrado gingival, el índice gingival y el índice de placa de soporte adherido, se realizó el procedimiento de raspado y pulido seguido de una sesión personalizada de consejos de higiene oral (CHO) para todos los sujetos del estudio. Se evaluaron los índices clínicos y se llevó a cabo la CHO a los 3, 6, 9 y 12 meses durante las visitas de tratamiento de ortodoncia. Resultados: Hubo una mejora significativa en los índices clínicos y la conciencia sobre la higiene oral y el nivel de salud periodontal en los pacientes al final del 12º mes. Conclusión: El programa de mantenimiento periodontal pareció ser eficaz para mejorar la salud periodontal y el nivel de conciencia de la salud sobre la higiene bucal entre los pacientes sometidos a terapia de ortodoncia fija al final de los 12 meses en nuestra población de estudio.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Young Adult , Oral Hygiene/psychology , Orthodontic Appliances, Fixed , Gingivitis , Surveys and Questionnaires , India/epidemiology
10.
J. oral res. (Impresa) ; 9(5): 383-391, oct. 31, 2020. graf, tab
Article in English | LILACS | ID: biblio-1179024

ABSTRACT

Objective: To describe the prevalence of oral manifestations of hypophosphatemic rickets in patients treated in a Peruvian referral pediatric hospital during the years 2012-2016. Material and methods: An observational, descriptive, retrospective, cross-sectional study was carried out. The sample consisted of patients diagnosed with hypophosphatemic rickets who attended the outpatient clinic of the Stomatology Service and the Genetics Service of the National Institute of Child Health (INSN), Lima, Peru, between the years 2012-2016. The research project was assessed and approved by the Research Ethics Committee of the Health Service. Medical records stored in a database of the health institution with the Code CIE E83.3, which corresponds to the diagnosis of Hypophosphatemic Rickets, were requested for the study. Results: Fifteen children received health care, of which only 10 were treated at the Stomatology Service. The distribution of the data was obtained from these 10 patients according to the proposed objective. A higher frequency of gingival lesions was found at the soft tissue level (41.18%); at the bone tissue level, only one case of dentigerous cyst was observed; and at the dental level, 90% of the patients had dental caries. Conclusion: The most frequent oral manifestations of hypophosphatemic rickets in pediatric patients treated at the National Institute of Child Health (2012-2016) were gingivitis and dental caries.


Objetivo:Describir la prevalencia de las manifestaciones bucales del raquitismo hipofosfatémico de pacientes atendidos en un hospital pediátrico de referencia peruano durante los años 2012-2016. Material y Métodos:Se realizó un estudio tipo observacional, descriptivo, retrospectivo, transversal. Para la selección de la muestra se consideró a los pacientes que acudieron a la consulta externa del Servicio de Odontoestomatología y el Servicio de Genética del Instituto Nacional de Salud del Niño, Lima, Perú; en el periodo comprendido entre los años 2012-2016 y que presentaron como diagnóstico Raquitismo Hipofosfatémico. El proyecto de investigación fue evaluado por un Comité de Ética en Investigación del servicio de salud. Se solicitaron las historias clínicas consignadas en una base de datos de la institución de salud con el Código CIE E83.3, que corresponde a este diagnóstico. Resultados: Fueron atendidos 15 niños, de los cuales solo 10 fueron tratados en el Servicio Odontoestomatología; siendo de estos 10 pacientes la distribución de los datos obtenidos según el objetivo propuesto. Se encontró mayor frecuencia de lesiones a nivel de tejido blando de gingivitis con 41.18%, a nivel de tejido óseo solo se presentó un caso de quiste dentígero; y a nivel de tejido dental el 90% de los pacientes presentó caries dental. Conclusión: Las manifestaciones bucales más frecuentes del raquitismo hipofosfatémico de pacientes pediátricos atendidos en el Instituto Nacional de Salud del Niño (2012-2016), fueron la gingivitis y caries dental.


Subject(s)
Humans , Male , Female , Tooth Diseases/etiology , Rickets, Hypophosphatemic/complications , Rickets, Hypophosphatemic/epidemiology , Oral Manifestations , Peru , Tooth Diseases/epidemiology , Dental Caries/etiology , Gingivitis/etiology
11.
Pesqui. vet. bras ; 40(9): 696-706, Sept. 2020. tab, ilus
Article in English | LILACS, VETINDEX | ID: biblio-1143425

ABSTRACT

Periodontal disease is the most common infectious disease that occurs in feline patients. Although it occurs in both sexes, different age groups, and any breeds, the prevalence and severity seem much higher in cats living in animal shelters. This paper aimed to describe the clinical, radiological, cytopathological, and virological aspects of periodontal disease and its complications in cats, based on these aspects and, consequently, on the importance it brings to cat feline medicine in shelter cats. For this, nine cats with periodontal disease from a single animal shelter were evaluated. These cats demonstrated a disease characterized by halitosis, excessive salivation, and oral discomfort. Lymphadenomegaly of the mandibular and retropharyngeal lymph nodes was observed in 44.4% of the cases. Oral lesions consisted of varying degrees of gingival hyperemia, complete loss of free gingival margins, and consequently gingival retraction, dental calculus deposition, dental mobility, complete exposure of the furcation of premolars and molars, and dental roots of canines and incisors, loss of bone radiopacity due to alveolar bone resorption and tooth loss. Complications included chronic ulcerative paradental stomatitis (22.2%), faucitis (22.2%), and chronic gingivostomatitis (11.1%). None of the cats affected by periodontal disease was positive for FIV or FeLV. In 33.3% of the cases, cats were carriers of feline calicivirus, but not feline herpesvirus.(AU)


Doença periodontal é a mais comum doença infecciosa que ocorre em pacientes felinos. Embora ocorra em gatos de ambos os sexos, diferentes faixas etárias e quaisquer raças, a prevalência e a gravidade parece muito maior em gatos que vivem em abrigos para animais. Baseado nesses aspectos e, consequentemente, na importância que ela traz para a medicina felina de gatos de abrigos, o objetivo desse artigo é descrever os aspectos clínicos, radiológicos, citopatológicos e virológicos da doença periodontal e suas complicações em gatos. Para isso, nove gatos com doença periodontal oriundos de um único abrigo de animais foram avaliados. Esses gatos demonstraram uma doença caracterizada por halitose, salivação excessiva e desconforto oral. Linfadenomegalia dos linfonodos mandibulares e retrofaríngeos foi observada em 44,4% dos casos. As lesões orais consistiam de graus variados de hiperemia gengival, perda completa das margens gengivais livres e, consequentemente, retração gengival, deposição de cálculo dental, mobilidade dentária, exposição completa da furca dos pré-molares e molares e das raízes dentárias dos caninos e incisivos, perda de radiopacidade óssea devido à reabsorção de osso alveolar e perda dentária. Complicações incluíram estomatite paradental ulcerativa crônica (22,2%), faucite (22,2%) e gengivoestomatite crônica (11,1%). Nenhum dos gatos afetados pela doença periodontal foi positivo para FIV ou FeLV. Em 33,3% dos casos, os gatos eram portadores do calicivírus felino, mas não do herpesvírus felino.(AU)


Subject(s)
Animals , Cats , Periodontal Diseases/complications , Periodontal Diseases/diagnosis , Periodontal Diseases/pathology , Periodontal Diseases/veterinary , Periodontal Diseases/epidemiology , Periodontitis/veterinary , Stomatitis/veterinary , Cat Diseases , Gingivitis/veterinary
12.
Int. j. odontostomatol. (Print) ; 14(2): 183-190, June 2020. tab
Article in English | LILACS | ID: biblio-1090673

ABSTRACT

The objective of this study is to show the distribution of periodontal disease, risk factors, and importance of primary healthcare, for the improvement of clinical parameters. Two phases study transversal and nonrandomized trial (before - after), with educational intervention and conservative treatment, were carried out at Dental School of the Universidad Autónoma de Guerrero México, in 161 subjects who met the inclusion criteria. Oral healthcare education was carried out as well as conservative periodontal treatment, with six months follow up. Clinical measurements were performed with a Williams probe, O'Leary plaque index, calculus index and dental mobility Miller method. Periodontal disease was found on 82 % of all participants. Multinomial logistic regression analysis showed an odds ratio of 14.3 (95 % CI: 2.5, 82.1), 13.4 (95 % CI: 1.7, 103.5), 29.2 (95 % CI: 3.2, 260.9) and 68 (95 % CI: 6.6, 711.0) plaque in gingivitis, mild, moderate and severe chronic periodontitis, respectively. The longitudinal panel data analysis showed a significant effect (p <0.001) in the mean decrease of the clinical parameters after intervention, probing depth 0.4 mm (95 % CI: -0.5, -0.3), pockets depth 1.1 mm (95 % CI: -1.3, -0.9), amount of pockets 4.5 (95 % CI: -5.2, -3.7), bleeding 5.2 (95 % CI: -5.9, -4.5) and dental mobility 0.6 degrees (95 % CI: -0.7, -0.5). Primary healthcare is still the best option to improve the periodontal health in population who do not have access to specialty services. Dentists can achieve significant clinical improvement at very low cost, if they are aware of primary health care.


El objetivo del estudio fue mostrar la distribución de la enfermedad periodontal, los factores de riesgo y la importancia de la atención primaria de salud, para la mejora de los parámetros clínicos. Material y método: Estudio de dos fases transversal y no aleatorizado (antes - después), con intervención educativa y tratamiento conservador, realizado en la Facultad de Odontología de la Universidad Autónoma de Guerrero México, en 161 sujetos que cumplieron con los criterios de inclusión. Se llevó a cabo una educación sanitaria oral, así como un tratamiento periodontal conservador, con un seguimiento de seis meses. Las mediciones clínicas se realizaron con una sonda Williams, el índice de placa O'Leary, el índice de cálculo y el método Miller de movilidad dental. Resultados: se encontró enfermedad periodontal en el 82 % de todos los participantes. El análisis de regresión logística multinomial mostró un odds ratio de 14.3 (IC 95 %: 2.5, 82.1), 13.4 (IC 95 %: 1.7, 103.5), 29.2 (IC 95 %: 3.2, 260.9) y 68 (IC 95 %: 6.6, 711.0) placa en gingivitis, periodontitis crónica leve, moderada y grave, respectivamente. El análisis de datos del panel longitudinal mostró un efecto significativo (p <0.001) en la disminución media de los parámetros clínicos después de la intervención, profundidad de sondeo 0.4 mm (IC 95 %: -0.5, -0.3), profundidad de bolsillos 1.1 mm (IC 95 %: -1.3, -0.9), cantidad de bolsillos 4.5 (IC 95 %: -5.2, -3.7), hemorragia 5.2 (IC 95 %: -5.9, -4.5) y movilidad dental 0.6 grados (IC 95 %: -0.7, - 0.5). Conclusiones: la atención primaria de salud sigue siendo la mejor opción para mejorar la salud periodontal en la población que no tiene acceso a servicios especializados. Relevancia clínica: los dentistas pueden lograr una mejora clínica significativa a un costo muy bajo, si conocen la atención primaria de salud.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Young Adult , Periodontal Diseases/epidemiology , Primary Health Care , Periodontal Diseases/therapy , Socioeconomic Factors , Logistic Models , Oral Health , Health Education , Cross-Sectional Studies , Risk Factors , Follow-Up Studies , Chronic Periodontitis/epidemiology , Conservative Treatment , Gingivitis/epidemiology , Mexico
14.
Periodontia ; 30(3): 26-31, 2020. tab
Article in English | LILACS, BBO | ID: biblio-1129608

ABSTRACT

Introduction: Due to inherent limitations of chlorhexidine, search for an effective and potentially safe anti-plaque agent has led to emergence of alternative products. Aim: To evaluate and compare the effects of Oral Pal Plus mouth rinse and chlorhexidine on dental plaque and gingivitis. Materials and Methods: The present study was randomized parallel group controlled trial. A group of 90 healthy subjects in the age group of 18-21 yrs received complete supragingival scaling at baseline and study variables viz, Plaque index and Gingival index were recorded. Subjects were then randomly divided into three groups (30 in each group) and were randomly intervened with three different mouthwashes. ie, Chlorhexidine, Oral Pal Plus and normal saline. Variables were again recorded on the 7th day 14th day after use of mouthwashes and data obtained was subjected to statistical analysis. Results: There was statistically significant reduction in plaque and gingival scores from baseline to 14 days in both the groups A & B. Conclusion: Chlorhexidine (0.2%) and Oral Pal Plus mouthwash showed significantly reduction in plaque scores and gingival scores whereas no improvement was seen in Group C using normal saline over 14 days. (AU)


Subject(s)
Chlorhexidine , Randomized Controlled Trial , Dental Plaque , Gingivitis
15.
Periodontia ; 30(3): 43-48, 2020. graf
Article in Portuguese | LILACS, BBO | ID: biblio-1129563

ABSTRACT

A gengivite tem se tornado a doença periodontal que apresenta maior prevalência na atualidade. Este trabalho tem como objetivo, avaliar a prevalência da gengivite associada ao biofilme em pacientes atendidos na Clínica Escola de Odontologia de um Centro Universitário no interior do Ceará, além de analisar, sexo, faixa etária, associação com alterações sistêmicas e o fumo. Desta forma, foi realizado um estudo epidemiológico de base de dados secundários, executado através de avaliação de prontuários de pacientes que foram atendidos no período de 2013 a 2018. Um total de 8.039 prontuários avaliados, apenas 2.821 (35%) atenderam aos critérios de inclusão. Diante dos dados (30%) foram identificados com saúde periodontal. Enquanto que a gengivite associada ao biofilme apresentou-se como sendo a alteração periodontal com maior prevalência em (74%) dos casos. O sexo feminino é dominante em (62%) dos pacientes. A faixa etária mais acometida foi de 30 a 44 anos. Em relação ao uso de tabaco, (78%) nunca fizeram uso. Por conseguinte, (86%) não apresentaram nenhum tipo de doença sistêmica. Conclui-se que mulheres normossistêmicas, não fumantes e acima de 30 anos de idade, apresentaram maior predisposição para o desenvolvimento de gengivite (AU)


Gingivitis has become the most prevalent periodontal disease now a days. The aim of this study is to evaluate the prevalence of gingivitis associated to biofilm in patients treated at the School of Dentistry Clinic of a University Center in Ceará, as well as to analyze gender, age, association with systemic changes and smoking. Thus, an epidemiological study of secondary database was performed, through the evaluation of medical records of patients who were attended from 2013 to 2018. A total of 8,039 medical records evaluated, only 2,821 (35%) met the inclusion criteria. Due to the data (30%) were identified with periodontal health. While gingivitis associated to biofilm was the most prevalent periodontal alteration in (74%) of the cases. Females are dominant in (62%) patients. The most affected age group was 30 to 44 years. Regarding tobacco use, (78%) never made use of it. Therefore, (86%) did not present any type of systemic disease. It was concluded that normosystemic women, non-smokers and over 30 years old, were more predisposed to the development of gingivitis. (AU)


Subject(s)
Humans , Periodontal Diseases , Prevalence , Gingivitis
16.
J. appl. oral sci ; 28: e20200276, 2020. tab, graf
Article in English | LILACS, BBO | ID: biblio-1134771

ABSTRACT

Abstract Objective: This study aimed to determine serum and salivary levels of neutrophil gelatinase-associated lipocalin (NGAL) and evaluate NGAL correlation with key anti-interleukin 10 (IL-10) and pro-inflammatory (IL-1β) cytokines in different severities of periodontal diseases. We also calculated the systemic inflammation using the periodontal inflamed surface area (PISA) to evaluate its correlation with NGAL in the study groups. Methodology: Eighty systemically healthy and non-smoking individuals were separated into four groups of 20: clinically healthy (Group 1), gingivitis (Group 2), stage I generalized periodontitis (Group 3, Grade A), and stage III generalized periodontitis (Group 4, Grade A). Sociodemographic characteristics and periodontal parameters were recorded, and PISA was calculated. The serum and salivary levels of interleukin (IL)-1β, IL-10, and NGAL were determined using the enzyme-linked immunosorbent assay (ELISA). Results: We observed a significant increase in serum and salivary NGAL levels from healthy to periodontitis groups (p=0.000). Group 2 presented significantly higher serum and salivary IL-10 levels and salivary IL-1β levels than Group 3 (p=0.000). Serum and salivary parameters (IL-1β, IL-10, and NGAL levels) were strongly positively correlated to periodontal parameters and PISA values (p=0.000). Groups 2 and 3 showed overlapping PISA values. Conclusion: The overlapping PISA values found in Groups 2 and 3 suggest that gingivitis might progress to a systemic inflammatory burden somewhat comparable to stage I periodontitis. This finding is supported by the higher serum and salivary cytokines/mediators levels in the gingivitis group than in stage I periodontitis group. Serum and salivary NGAL levels increased proportionally to disease severity and PISA. NGAL seems to play a role in the pathogenesis of periodontal disease, within the limitation of our study.


Subject(s)
Humans , Female , Periodontal Diseases , Periodontitis , Lipocalin-2/metabolism , Gingivitis , Arteritis , Lipocalin-2/blood
17.
J. appl. oral sci ; 28: e20190490, 2020. tab, graf
Article in English | LILACS, BBO | ID: biblio-1090781

ABSTRACT

Abstract The relationship between periodontitis and the pathogenesis of other inflammatory diseases, such as diabetes, rheumatoid arthritis and obesity has been an important topic of study in recent decades. The Th17 pathway plays a significant role in how local inflammation can influence systemic inflammation in the absence of systemic pathology. Objective: To determine Th17 biased-cells in systemically healthy patients in the presence of generalized chronic periodontitis. Methodology: A total of 28 patients were recruited without systemic inflammatory pathology, which was determined by clinical history, the Health Assessment Questionnaire (HAQ) and rheumatoid factor detection. Of these patients, 13 were diagnosed as healthy/gingivitis (H/G) and 15 as generalized chronic periodontitis (GCP). Th17 (CD4+CD161+) cells and Th17IL23R+ (CD4+CD161+IL-23R+) cells were quantified by flow cytometry, based on the total cells and on the lymphocyte region, termed the "enriched population" (50,000 events for each). Results: The percentages of Th17 cells of the H/G and periodontitis groups were similar on total cells and enriched population (19 vs 21.8; p=4.134 and 19.6 vs 21.8; p=0.55). However, Th17IL23R+ cells differ significantly between periodontally healthy patients and generalized chronic periodontitis patients in both total cell (0.22% vs 0.65%; p=0.0004) and enriched populations (0.2% vs 0.75%; p=0.0266). Conclusions: GCP patients (otherwise systemically healthy) were characterized by increased Th17-proinflammatory cell phenotype positive for the IL-23 receptor in peripheral blood. The proportion of Th17 cells that are negative for the IL-23 receptor in the peripheral blood of systemically healthy patients seemed to be unaffected by the presence or absence of chronic periodontitis.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Chronic Periodontitis/immunology , Th17 Cells/immunology , Phenotype , Case-Control Studies , Periodontal Index , Surveys and Questionnaires , Receptors, Interleukin/blood , Statistics, Nonparametric , Interleukin-23/blood , Chronic Periodontitis/pathology , Th17 Cells/pathology , Flow Cytometry , Gingivitis/immunology , Gingivitis/pathology
18.
Rev. bras. epidemiol ; 23: e200051, 2020. tab
Article in English | LILACS | ID: biblio-1101588

ABSTRACT

ABSTRACT: Introduction: Oral health-related quality of life (OHRQoL) is affected by different clinical conditions. The aim of this study was to evaluate the impact of gingivitis on OHRQoL in adolescents. Methodology: This cohort study consisted of a random sample of 1,134 schoolchildren enrolled during 2012, in Santa Maria, Brazil. After two years, 743 adolescents were follow-up (response rate: 65.5%). Clinical, socioeconomic and OHRQoL data were collected. OHRQoL was assessed by the short Brazilian version of the Child Perceptions Questionnaire 11-14 (CPQ11-14), and gingival bleeding through Community Periodontal Index. Gingivitis was considered with the presence of 15% or more bleeding sites. Poisson regression models were used to evaluate the association between gingivitis and overall and domain-specific CPQ11-14 scores. Prevalence of gingivitis at baseline was considered the main predictor for the OHRQoL at follow-up. Results: Gingivitis at baseline was associated with higher overall CPQ 11-14 score (RR = 1.07; 95%CI 1.01 - 1.14), and emotional well-being (RR = 1.17; 95%CI 1.04 - 1.31), independently of other oral conditions and socioeconomic variables. Conclusions: The findings indicate that gingivitis negatively impacts the adolescents' OHRQoL. Moreover, gender, maternal schooling and household income were also associated with OHRQoL.


RESUMO: Introdução: Qualidade de vida relacionada à saúde bucal (QVRSB) é afetada por diferentes condições clínicas. O objetivo deste estudo foi avaliar o impacto da gengivite na QVRSB de adolescentes. Metodologia: Este estudo de coorte consistiu em uma amostra aleatória de 1.134 escolares iniciado em 2012, na cidade de Santa Maria, Brasil. Após dois anos, 743 adolescentes foram acompanhados (taxa de resposta: 65,5%). Dados clínicos, socioeconômicos e de QVRSB foram coletados. A QVRSB foi avaliada pela versão brasileira curta do Child Perceptions Questionnaire 11-14 (CPQ11-14) e o sangramento gengival foi coletado através do Índice Periodontal Comunitário. Gengivite foi considerada com o indivíduo apresentando 15% ou mais locais de sangramento. Os modelos de regressão de Poisson foram utilizados para avaliar a associação entre gengivite e os escores total e específico do domínio do CPQ11-14. A prevalência de gengivite na primeira avaliação foi considerada o preditor principal para a QVRSB no acompanhamento. Resultados: A gengivite no baseline foi associada à maior pontuação geral do CPQ 11-14 (RR = 1,07; IC95% 1,01 - 1,14) e ao domínio de bem-estar emocional (RR = 1,17; IC95% 1,04 - 1,31), independentemente das outras condições orais e variáveis socioeconômicas. Conclusão: Os achados indicam que a gengivite impacta negativamente a QVRSB de adolescentes. Além disso, sexo, escolaridade materna e renda familiar mensal também foram associados à QVRSB.


Subject(s)
Humans , Male , Female , Child , Adolescent , Quality of Life , Gingivitis/psychology , Socioeconomic Factors , Brazil/epidemiology , Gingival Hemorrhage/psychology , Oral Health , Surveys and Questionnaires , Cohort Studies , Longitudinal Studies , Tooth Injuries/psychology , Dental Caries/psychology , Gingivitis/epidemiology
19.
Braz. oral res. (Online) ; 34: e015, 2020. tab, graf
Article in English | LILACS | ID: biblio-1089381

ABSTRACT

Abstract We sought to compare the characteristics and clinical significance of neutrophil extracellular traps in gingival samples from patients with periodontitis and those with gingivitis. The clinical indexes of gingival samples from patients with periodontitis and gingivitis were measured; the expression of TNF-alpha and IL-8 was measured by real-time fluorescent quantitative PCR; and the expression of TLR-8 and MMP-9 was measured by western blotting assays. Chemotaxis, phagocytosis and phagocytic activity of neutrophils were measured. Compared with the healthy group, the expression of TNF-α and IL-8 in the periodontitis group and the gingivitis group increased significantly (p < 0.05), and TNF-α in the gingivitis group was significantly lower than that in the healthy group (p < 0.05). The expression of IL-8 in the periodontitis group was significantly higher than that in the periodontitis group (p < 0.05). Furthermore, the expression of TLR-8 and MMP-9 in the periodontitis group was different from that in the gingivitis group and the healthy group, and the expression of TLR-8 and MMP-9 in the gingivitis group was significantly different from that in the healthy group (p < 0.05). In addition, the neutrophil mobility index in healthy people was 3.02 ± 0.53, that in the periodontitis group was 2.21 ± 0.13, and that in the gingivitis group was 2.31 ± 0.12. In conclusion, the chemotaxis of neutrophils in gingival samples of patients with periodontitis and gingivitis was decreased, the phagocytotic ability and activity of neutrophils were reduced, and the release of the extracellular trap-releasing inducible factors TNF-alpha and IL-8 also declined.


Subject(s)
Humans , Male , Female , Young Adult , Periodontitis/pathology , Extracellular Traps , Gingivitis/pathology , Neutrophils/pathology , Reference Values , RNA/analysis , Case-Control Studies , Periodontal Index , Blotting, Western , Interleukin-8/analysis , Actins/analysis , Tumor Necrosis Factor-alpha/analysis , Matrix Metalloproteinase 9/analysis , Electrophoresis, Agar Gel , Toll-Like Receptor 8/analysis , Real-Time Polymerase Chain Reaction , Middle Aged
20.
Braz. oral res. (Online) ; 34: e012, 2020. graf
Article in English | LILACS | ID: biblio-1055530

ABSTRACT

Abstract Lipoproteins are important bacterial immunostimulating molecules capable of inducing receptor activator of nuclear factor-κB (RANKL) and osteoclast formation in vitro and in vivo . Although these molecules are present in periodontopathogenic bacteria, their role in periodontitis is not known. In this study, we used Pam2CSK4 (PAM2), a synthetic molecule that mimics bacterial lipoprotein, to investigate the effects of lipoproteins on periodontitis in mice. C57BL/6 male mice were randomly divided into three experimental groups: 1) Negative control group: animals received vehicle injection; 2) Positive control group: animals received injection of Escherichia coli lipopolysaccharide (LPS); 3) PAM2 group: animals received PAM2 injection. All the injections were performed bilaterally every other day into the palatal mucosa between first and second molars. After twenty-four days, the animals were euthanized to assess alveolar bone volume (micro-CT), cellular and extracellular composition in the gingiva (stereometric analysis), and osteoclast numbers (TRAP staining). Treatment with either PAM2 or LPS induced gingival inflammation, as demonstrated by increased infiltration of inflammatory cells and enhanced angiogenesis, associated with a smaller number of fibroblasts and decreased extracellular matrix. Importantly, treatment not only with LPS but also with PAM2 resulted in a larger number of TRAP+ multinucleated osteoclasts and significant loss of alveolar bone. Collectively, our data demonstrate that PAM2 can induce gingival inflammation and bone loss in mice, broadening the avenues of investigation into the role of lipoproteins in the pathogenesis of periodontal disease.


Subject(s)
Animals , Male , Periodontitis/etiology , Periodontitis/pathology , Toll-Like Receptor 2/antagonists & inhibitors , Lipopeptides/pharmacology , Osteoclasts/drug effects , Periodontitis/microbiology , Time Factors , Random Allocation , Alveolar Bone Loss/etiology , Alveolar Bone Loss/pathology , Disease Models, Animal , X-Ray Microtomography , Alveolar Process/drug effects , Alveolar Process/pathology , Tartrate-Resistant Acid Phosphatase , Gingiva/drug effects , Gingiva/pathology , Gingivitis/etiology , Gingivitis/pathology , Mice, Inbred C57BL
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