Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 709
Filter
1.
Braz. j. biol ; 82: e245813, 2022. tab, graf
Article in English | MEDLINE, LILACS, VETINDEX | ID: biblio-1285592

ABSTRACT

Abstract Hepatitis B virus infection is perilous among the five types of Hepatitis, as it remains clinically asymptomatic. The present study draws up-to-date prevalence of Hepatitis B virus (HBV) in the general population of Mardan, Khyber Pakhtunkhwa Pakistan. The blood samples from 4803 individuals including 2399 male and 2404 females were investigated. All the suspected samples were analyzed for hepatitis B surface antigen using Immuno-chromatographic test (ICT), Enzyme-linked immunosorbent assay (ELISA), and followed by Reverse transcription-polymerase chain reaction (RT-PCR). Results showed that 312 (13.00%) out of 2399 individuals contained antibodies in their blood against HBV, while among the different age groups, the highest incidences of HBV antibodies were found in the age of 21-30 groups (10.73%). Furthermore, the ICT positive samples were screened by nested polymerase chain reaction to detect the existence of active HBV-DNA. It was observed that 169 (7.04%) out of (2399) male of the total population (4803) tested was positive. On the other hand, the female 463 (19.25%) possessed antibodies in their blood against HBV. Accumulatively, our results showed a higher percentage of HBV prevalence in males than females in the age group 21-30 years. The total HCV infected in Mardan general population was recorded at 5.7% comprising both male and female.


Resumo A infecção pelo vírus da hepatite B é perigosa entre os cinco tipos de hepatite, pois permanece clinicamente assintomática. O presente estudo traça a prevalência atualizada do vírus da hepatite B (HBV) na população geral de Mardan, Khyber Pakhtunkhwa, no Paquistão. Amostras de sangue de 4.803 indivíduos, incluindo 2.399 homens e 2.404 mulheres, foram investigadas. Todas as amostras suspeitas foram analisadas para o antígeno de superfície da hepatite B usando teste imunocromatográfico (ICT), enzyme-linked immunosorbent assay (ELISA), seguido por transcrição reversa-reação em cadeia da polimerase (RT-PCR). Os resultados mostraram que 312 (13,00%) de 2.399 indivíduos continham anticorpos no sangue contra o VHB, enquanto, entre as diferentes faixas etárias, as maiores incidências de anticorpos VHB foram encontradas nos grupos de 21 a 30 anos (10,73%). Além disso, amostras positivas para ICT foram rastreadas por reação em cadeia da polimerase aninhada para detectar a existência de HBV-DNA ativo. Observou-se que 169 (7,04%) de 2.399 homens do total da população (4803) testados foram positivos. Por outro lado, 463 mulheres (19,25%) possuíam anticorpos no sangue contra VHB. Acumulativamente, nossos resultados mostraram uma porcentagem maior de prevalência de HBV em homens do que em mulheres na faixa etária de 21 a 30 anos. O total de HCV infectados na população geral de Mardan foi registrado em 5,7%, incluindo homens e mulheres.


Subject(s)
Humans , Male , Female , Adult , Young Adult , Hepatitis B virus/genetics , Hepatitis B/epidemiology , Pakistan/epidemiology , Prevalence , Hepatitis B Surface Antigens
2.
Rev. Bras. Saúde Mater. Infant. (Online) ; 21(3): 945-953, July-Sept. 2021. tab, graf
Article in English | LILACS | ID: biblio-1346996

ABSTRACT

Abstract Objectives: to calculate the prevalence and rate per 1,000 live births of sexually transmitted infections (STI) in pregnant women at a public maternity hospital in Salvador. Methods: this descriptive, cross-sectional study retrospectively collected data from compulsory notifications and medical records of pregnant women with STI seen at a maternity hospital in northeastern Brazil between 2014 and 2017 (n = 520). Prevalence and rate per 1,000 live births were estimated for hepatitis B, hepatitis C, HIV, and syphilis. Associations between STI and other clinical and sociodemographic variables were investigated. Results: most pregnant women were born and resided in Salvador, presented a mean age of 26.4 years, self-reported mixed-race and had unplanned pregnancies. Prevalence and rates per 1,000 live births were, respectively: 0.26% and 3.39 for hepatitis B, 0.06% and 0.79 for hepatitis C, 0.47% and 6.23 for HIV, and 2.46% and 32.2 for syphilis. Conclusion: higher prevalence and rates of infection per 1,000 live births were seen at the maternity hospital in northeastern Brazil compared to official data provided by the Brazilian government, notably with regard to HIV and syphilis. The appropriate epidemiological notification of STI, especially in pregnant women, enables the elaboration of effective preventive strategies incorporating specific sociodemographic and clinical characteristics.


Resumo Objetivos: calcular a prevalência e as taxas por 1000 nascidos vivos de infecções sexualmente transmissíveis (IST) em gestantes de uma maternidade pública de Salvador. Métodos: estudo transversal, descritivo, com dados coletados retrospectivamente a partir das fichas de notificação dos agravos e dos prontuários de todas as gestantes com IST atendidas na maternidade, entre os anos de 2014 e 2017 (n=520). Foram calculadas as prevalências e as taxas por 1000 nascidos vivos de hepatite B, hepatite C, HIV e sífilis para a população de gestantes da maternidade. Associações entre as IST e demais variáveis clínicas e sociodemográficas também foram investigadas. Resultados: a maioria das gestantes era natural e residente de Salvador, pardas, com idade média de 26,4 anos e que não planejaram a gravidez. As prevalências e as taxas por 1000 nascidos vivos foram respectivamente: 0,26% e 3,39 para hepatite B, 0,06% e 0,79 para hepatite C, 0,47% e 6,23 para HIV e 2,46% e 32,2 para sífilis. Conclusão: a maternidade apresenta prevalências e taxas por 1000 nascidos vivos superiores aos dados oficiais do governo brasileiro, especialmente para HIV e sífilis. A correta notificação epidemiológica desses agravos, especialmente em gestantes, permite o desenvolvimento de estratégias preventivas mais eficientes e com enfoque nas características sociodemográficas e clínicas das pacientes.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Syphilis/transmission , Syphilis/epidemiology , HIV Infections/transmission , HIV Infections/epidemiology , Hepatitis C/transmission , Hepatitis C/epidemiology , Pregnant Women , Hepatitis B/transmission , Hepatitis B/epidemiology , Socioeconomic Factors , Brazil/epidemiology , Sexually Transmitted Diseases/epidemiology , Cross-Sectional Studies , Live Birth , Health Information Systems
3.
Arq. gastroenterol ; 58(2): 150-156, Apr.-June 2021. tab, graf
Article in English | LILACS | ID: biblio-1285316

ABSTRACT

ABSTRACT BACKGROUND: Viral hepatitis is a global phenomenon, with the disease burden varying on a daily basis. Amongst chronic infections, hepatitis B virus and hepatitis C virus (HCV) are egregiously linked to severe health-related complications, with a worldwide prevalence of 248 million and 71 million respectively. Amongst the developing world, a hand full of countries are exhibiting a gross decline in chronic viral infection prevalence, like Bangladesh. While countries such as India have a consistent prevalence, Pakistan bears one of the largest proportions of chronic viral hepatitis globally with increasing trends shown year-by-year. Various old literature texts have stated an approximate national prevalence rate around 2.6% and 5.3% of hepatitis B and C respectively. OBJECTIVE: The objective of this study was to determine the current seroprevalence rates of chronic viral hepatitis amongst the general population of rural Sindh using a screening program to determine the current disease burden. METHODS: An observational, cross-sectional survey based on a screening program was conducted in 5 districts with a combined population of over 6.5 million. The screening was carried out via the administration of various camps with the assistance of local social workers and welfare organizations. A total of 24,322 individuals met the inclusion criteria and were screened through (HBsAg/HCV) rapid test cassette (WC) Imu-Med one-step diagnostic test. RESULTS: Hepatitis B was found positive in 964 (3.96%) individuals including 421 (43.67%) males and 543 (56.32%) females, while hepatitis C was positive in 2872 (11.80%) individuals including 1474 (51.32%) males and 1398 (48.67%) females. The prevalence amongst the districts varied between 0.97% and 9.06% for hepatitis B, and 1.61% and 29.50% for hepatitis C, respectively. Umerkot was found to be the most prevalent district amongst rural Sindh, while Badin had the least number of seropositive people. The second most prevalent district of the study population was found to be Tando Allahyar followed by Mirpur Khas. The combined seroprevalence of 15.76% was calculated for hepatitis B and C together amongst the five studied districts of rural and peri-urban Sindh. CONCLUSION: The alarmingly high prevalence rates revealed in our study warrant the urgent need to generate multiple effective strategies in the region to enhance awareness amongst the general population regarding screening, prevention, and prompt treatment of the disease.


RESUMO CONTEXTO: A hepatite viral é um fenômeno global, com a intensidade da doença variando diariamente. Entre as infecções crônicas, o vírus da hepatite B e o vírus da hepatite C (VHC) estão fortemente ligados a complicações graves relacionadas à saúde, com prevalência mundial de 248 milhões e 71 milhões, respectivamente. Entre o mundo em desenvolvimento, uma quantidade de países está exibindo um declínio bruto na prevalência de infecção viral crônica, tal como Bangladesh. Embora países como a Índia tenham uma prevalência consistente, o Paquistão tem uma das maiores proporções globais de hepatite viral crônica, com tendências crescentes mostradas ano a ano. Vários textos da menos recentes têm declarado uma taxa de prevalência nacional aproximada em torno de 2,6% e 5,3% da hepatite B e C, respectivamente. OBJETIVO: O objetivo deste estudo foi determinar as atuais taxas de soroprevalência da hepatite viral crônica entre a população geral do Sindh rural utilizando um programa de triagem para determinar a carga atual da doença. MÉTODOS: Foi realizada uma pesquisa observacional e transversal baseada em um programa de triagem combinada em cinco distritos com população de mais de 6,5 milhões. A triagem foi realizada por meio da administração de diversos acampamentos com o auxílio de assistentes sociais locais e organizações de assistência social. Um total de 24.322 indivíduos atenderam aos critérios de inclusão e foram examinados através do teste rápido (HBsAg/VHC) Imu-Med em uma etapa. RESULTADOS: Hepatite B positiva foi encontrada em 964 (3,96%) indivíduos incluindo 421 (43,67%) homens e 543 (56,32%) mulheres, enquanto hepatite C foi positiva em 2.872 (11,80%) indivíduos incluindo 1.474 (51,32%) homens e 1.398 (48,67%) mulheres. A prevalência entre os distritos variou entre 0,97% e 9,06% para hepatite B, e 1,61% e 29,50% para hepatite C, respectivamente. Umerkot foi encontrado como o distrito mais prevalente entre Sindh rural, enquanto Badin tinha o menor número de pessoas soropositivas. O segundo distrito mais prevalente da população de estudos foi encontrado como Tando Allahyar, seguido por Mirpur Khas. A soroprevalência combinada de 15,76% foi calculada para hepatite B e C em conjunto entre os cinco distritos estudados do Sindh rural e periurbano. CONCLUSÃO: As taxas de prevalência alarmantemente reveladas em nosso estudo justificam a necessidade urgente de gerar múltiplas estratégias efetivas na região para aumentar a conscientização da população em geral sobre rastreamento, prevenção e tratamento rápido da doença.


Subject(s)
Humans , Male , Female , Hepatitis C/diagnosis , Hepatitis C/epidemiology , Hepatitis B/diagnosis , Hepatitis B/epidemiology , Pakistan/epidemiology , Seroepidemiologic Studies , Prevalence , Cross-Sectional Studies
4.
Rev. bras. ginecol. obstet ; 43(3): 216-219, Mar. 2021. tab
Article in English | LILACS | ID: biblio-1251309

ABSTRACT

Abstract Objective To evaluate the seroprevalence of positive markers for syphilis, human immunodeficiency virus (HIV) I and II, human T cell lymphotropic virus (HTLV) I and II, and hepatitis B and C among women undergoing in vitro fertilization (IVF). Methods We conducted a retrospective analysis among patients who underwent IVF, between January 2013 and February 2016, and who had complete screening records. Results We analyzed 1,008 patients who underwent IVF, amounting to 2,445 cycles. Two patients (0.2%) tested positive for HIV I and II and none for HTLV I and II. Three patients (0.3%) had positive screening for syphilis, and two (0.2%) had positive hepatitis C antibody test (anti-HCV). A positive hepatitis B virus surface antigen (HbsAg) test was observed in 4 patients (0.4%), while 47 (4.7%) patients were positive for IgG antibody to hepatitis B core antigen (anti-HbC IgG), and only 1 (0.1%) was positive for IgM antibody to hepatitis B core antigen (anti-HbC IgM). The anti-HbS test was negative in 659 patients (65.3%). Only 34.7% of the patients had immunity against the Hepatitis B virus. Patients with an anti-HbS negative result were older than those with a hepatitis B test (anti-HbS) positive result (36.3 versus 34.9; p<0.001). Conclusion The present study showed lower infection rates than the Brazilian ones for the diseases studied in patients undergoing IVF. Only a few patients were immunized against hepatitis B.


Resumo Objetivo Avaliar a soroprevalência de marcadores positivos para sífilis, vírus da imunodeficiência humana (HIV) I e II, vírus linfotrópicos de células T humanas (HTLV) I e II e hepatite B e C em mulheres submetidas a fertilização in vitro (FIV). Métodos Realizamos uma análise retrospectiva entre as pacientes submetidas a FIV, entre janeiro de 2013 e fevereiro de 2016, e que possuíam prontuários completos. Resultados Foram analisadas 1.008 pacientes submetidas a FIV, totalizando 2,445 ciclos. Duas pacientes (0,2%) apresentaram resultado positivo para HIV I e II, e nenhuma para HTLV I e II. Três pacientes (0,3%) apresentaram triagem positiva para sífilis, e duas (0,2%) apresentaram teste de pesquisa de anticorpos anti-HCV (anti-HCV) positivo. Um teste de antígeno de superfície do vírus da hepatite B (HbsAg) positivo foi observado em 4 pacientes (0,4%), enquanto 47 (4,7%) pacientes foram positivas para anticorpos IgG contra o antígeno de superfície da hepatite B (IgG anti-HbC), e apenas 1 (0,1%) foi positiva para anticorpos IgM contra o antígeno central da hepatite B (IgM anti-HbC). O teste de anticorpos contra hepatite B (anti-HbS) foi negativo em 659 pacientes (65,3%). Apenas 34,7% das pacientes tinham imunidade contra o vírus da hepatite B. Pacientes comresultado negativo anti-HbS erammais velhas do que aquelas com resultado positivo anti-HbS (36,3 versus 34,9; p<0,001). Conclusão Este estudo mostrou taxas de infecção inferiores às taxas brasileiras para as doenças estudadas em pacientes submetidas à FIV. Apenas alguns pacientes foram imunizados contra a hepatite B.


Subject(s)
Humans , Female , Adult , Fertilization in Vitro , Blood-Borne Infections/epidemiology , Infertility, Female , Brazil/epidemiology , Syphilis/blood , Syphilis/epidemiology , HIV Infections , HIV Infections/blood , Seroepidemiologic Studies , Retrospective Studies , Hepatitis C/blood , Hepatitis C/epidemiology , Blood-Borne Infections/blood , Hepatitis B/blood , Hepatitis B/epidemiology
6.
Ciênc. Saúde Colet ; 26(3): 1173-1182, mar. 2021. tab, graf
Article in English, Portuguese | LILACS | ID: biblio-1153826

ABSTRACT

Resumo O objetivo deste artigo é analisar a distribuição espacial da vacina contra Hepatite B (VCHB) de gestantes. Estudo transversal, realizado com 266 puérperas. O registro da VCHB foi obtido por meio da caderneta de pré-natal. Para a detecção do cluster de risco para presença de registro ou ausência de VCHB foi utilizada a técnica de varredura espacial. Posteriormente a esta identificação do cluster, procedeu-se à comparação das variáveis individuais e ambientais entre as Áreas de Abrangência da Unidade Básica de Saúde (AA-UBS). A prevalência média de não VCHB foi de 88,34%. A análise de varredura espacial Scan observou-se um cluster de alta prevalência de puérperas que apresentava o registro da VCHB em suas cadernetas. Análises comparativas demonstraram que trabalho remunerado e o número de consultas realizadas no pré-natal estão associados positivamente a VCHB. Este trabalho suscita uma reflexão de possíveis disparidades com as demais AA-UBS, além da perspectiva a nível ambiental. Ressalta-se que a situação vacinal sofre influência não somente de fatores intrínsecos aos indivíduos, entretanto, nesse estudo, os resultados apontam que as variáveis individuais são majoritariamente mandatórias na decisão das gestantes em vacinarem.


Abstract The objective of this article is to analyze the spatial distribution of Hepatitis B vaccine (HBVAC) of pregnant women. This is a cross-sectional study carried with 266 puerperae. The HBVAC record was obtained through the prenatal care booklet. The spatial scanning technique was used to detect a cluster of risk for the presence or absence of an HBVAC record. After this cluster identification, the individual and environmental variables were compared between the Coverage Areas of Basic Health Units (CAs-BHUs). The mean prevalence of non-HBVAC was 88.34%. Scan spatial scan analysis observed a cluster of a high prevalence of puerperae with a HBVAC record. Comparative analyses have shown that paid work and the number of prenatal visits are positively associated with an HBVAC record. Given the above, this work brings a reflection on possible disparities with other CAs-BHUs, besides the influence of the environmental perspective. It should be emphasized that the vaccination situation is influenced not only by factors intrinsic to the individuals. However, in this study, the results indicate that individual variables are predominantly mandatory in the decision of HBVAC uptake among pregnant women.


Subject(s)
Humans , Female , Pregnancy , Pregnant Women , Hepatitis B/prevention & control , Hepatitis B/epidemiology , Brazil/epidemiology , Cross-Sectional Studies , Vaccination , Spatial Analysis
7.
ABCS health sci ; 46: e021219, 09 fev. 2021. tab
Article in English | LILACS | ID: biblio-1343345

ABSTRACT

INTRODUCTION: Hepatitis B (HB) vaccination for health-care workers is essential for World Health Organization's goals achievement of viral hepatitis (VH) elimination. However, recent studies showed low vaccination adherence by these professionals and lack of knowledge about HB vaccination adherence of community health workers (CHW). OBJECTIVE: To identify the adherence of CHW to HB vaccination; to determine the causes of non-adherence; to investigate whether the prevalence of vaccination is different among surveyed towns, and to verify whether years practiced as CHW have any association with vaccination adherence. METHODS: This cross-sectional study included five towns (T) of a Brazilian state. Data were collected at VH educational meetings, in which CHW answered a questionnaire. The proportions Z-test and the likelihood ratio test were used for statistical analysis. Significance was set at p<0.05. RESULTS: The sample included 516 CHW. Most CHW (86.8%) reported to have taken the vaccine, but only 59.7% affirmed having taken all doses, and 28.1% correctly answered the number of doses. 24.4% of CHW pointed the unknowing about HB vaccine importance as the main reason for non-adherence. T4 and T5 showed higher vaccination prevalence than T2 and T1. Vaccination adherence was higher among individuals with more years working as CHW. CONCLUSION: CHW demonstrated low adherence to HB vaccination and pointed the lack of knowledge about HB vaccine importance as the main reason for that. There were differences in vaccination prevalence among the towns and adherence was positively associated with professional experience.


INTRODUÇÃO: A vacinação dos profissionais de saúde contra hepatite B (HB) é fundamental para que sejam atingidas as metas da Organização Mundial de Saúde de eliminação das hepatites virais (HV). Entretanto, estudos recentes mostram baixa aderência desses profissionais à vacinação e falta conhecimento sobre a adesão dos agentes comunitários de saúde (ACS) à vacinação. OBJETIVO: Identificar a adesão dos ACS à vacinação contra HB; determinar as causas da não adesão; investigar se a prevalência de vacinação é diferente entre os municípios (M) pesquisados; e verificar se o tempo de experiência como ACS está associado à adesão. MÉTODOS: Estudo transversal incluindo cinco municípios de um estado brasileiro. Os dados foram coletados em palestras sobre HB, nas quais os ACS responderam um questionário. Foram aplicados o teste de proporções (Z) e a razão de verossimilhança, considerando-se significante p<0,05. RESULTADOS: A amostra incluiu 516 ACS, dos quais 86,8% relataram ter tomado a vacina, 59,7% afirmaram ter tomado todas as doses, 28,1% responderam corretamente o número de doses e 24,4% apontaram o desconhecimento sobre a importância da vacina como o principal motivo de não adesão. M4 e M5 mostraram maior prevalência de vacinação que M2 e M1. Os ACS com maior tempo de experiência profissional apresentaram maior adesão. CONCLUSÃO: Os ACS demonstraram baixa adesão à vacinação contra HB e indicaram a falta de conhecimento sobre a importância da vacina como a principal causa. Houve diferenças na prevalência de vacinação entre os municípios e a aderência foi positivamente associada ao tempo de experiência profissional.


Subject(s)
Humans , Vaccination , Community Health Workers , Hepatitis B/prevention & control , Hepatitis B/epidemiology , Cross-Sectional Studies
8.
Rev. Soc. Bras. Med. Trop ; 54: e00892020, 2021. graf
Article in English | ColecionaSUS, LILACS, ColecionaSUS, SES-SP | ID: biblio-1143879

ABSTRACT

Abstract INTRODUCTION: Viral hepatitis is a major public health problem. It is necessary to understand the epidemic, verifying the combination of biological and demographic characteristics. METHODS: This is an analytical ecological and epidemiological study. Confirmed case data from the Notification Disease Information System (SINAN) were used. RESULTS: From 2009-2018, SINAN confirmed 404,003 viral hepatitis cases in Brazil, with 12.49%, 37.06%, and 48.28% cases of hepatitis A, B, and C, respectively. CONCLUSIONS: In Brazil, 4,296 deaths were associated with viral hepatitis, of which 36.66% were associated with acute hepatitis B. The proportional distribution of cases varied among the five Brazilian regions.


Subject(s)
Humans , Hepatitis B/epidemiology , Hepatitis, Viral, Human/epidemiology , Brazil/epidemiology , Epidemiologic Studies , Incidence
9.
Rev. chil. salud pública ; 24(1): 30-39, 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1121731

ABSTRACT

INTRODUCCIÓN: Las infecciones de transmisión sexual (ITS) se expresan con mayor frecuencia en poblaciones marginadas, como lo son los ciudadanos que se encuentran en situación de calle y con problemas de drogadicción. MATERIALES Y MÉTODOS: Mediante un estudio de campo descriptivo retrospectivo, se determinó la prevalencia de las ITS que se detallan en los ciudadanos residentes de un Centro de Inclusión Social en Venezuela durante los años 2013 a 2018. Para ello, suero de 280 individuos fue analizado mediante la prueba ELISA de diferentes compañías biotecnológicas. RESULTADOS: 50 casos (17,8%) fueron reactivos a cualquiera de las enfermedades investigadas. El biomarcador de mayor prevalencia durante el lapso estudiado fue el antiHBc con 13,9% y las menores fueron HBsAg con 0,75%, VHC con 0,71% y Treponema pallidum con 2,85%, así como 2,14% para VIH. No se detectó ningun caso de HTLV. Del mismo modo, se observó una tasa de co-infección entre hepatitis B y VIH de 2,32%, entre hepatitis C y VIH de 1,5% y en dos años se consiguió co-infeccion de hepatitis B y Sífilis con 1,5% y 5,8% en el 2014 y 2018 respectivamente. DISCUSIÓN: Se encontró que los sujetos acogidos en el Centro de Inclusión Social son un grupo vulnerable a las ITS y las coinfecciones, por lo que deben llevarse a cabo campañas de preven-ción y pruebas de detección de estas enfermedades en dicha población.


INTRODUCTION: Sexually Transmitted Infections (STIs) are most frequently expressed in marginalized populations, such as as homeless individuals or those with substance abuse issues. MATERIALS AND METHODS: Through a retrospective descriptive study, the prevalence of various STDs was determined among residents of a Social Inclusion Center in Venezuela from 2013 to 2018. For this purpose, serum from 280 individuals were analyzed with ELISA tests from different biotech companies. RESULTS: 50 cases (17.86%) were sero-reactive to any of the STIs investigated. The most preva-lent biomarker during the study period studied was antiHBc (13.9%) and the lowest prevalen-ces were HBsAg with 0.75%, HCV with 0.71%, and Treponema pallidum with 2.85%, as well as 2.14% for HIV. No cases of HTLV were detected. Similarly, there was coinfection between hepatitis B and HIV in 2.32% of cases, between hepatitis C and HIV in 1.5%, and between syphillis and hepatitis in 1,5% and 5,8% of cases (in 2014 and 2018 respectively). DISCUSSION: Individuals in Centers for Social Inclusion are at risk of presenting STIs and co-infections; therefore, STI prevention campaigns and screenings should be conducted in this vulnerable group.


Subject(s)
Humans , Male , Sexually Transmitted Diseases/diagnosis , Sexually Transmitted Diseases/epidemiology , Venezuela/epidemiology , Enzyme-Linked Immunosorbent Assay , Biomarkers/analysis , Serotyping , HIV Infections/epidemiology , Epidemiology, Descriptive , Prevalence , Retrospective Studies , Hepatitis C/epidemiology , Vulnerable Populations , Coinfection , Hepatitis B/epidemiology
10.
Rev. Soc. Bras. Med. Trop ; 53: e20190282, 2020. tab
Article in English | LILACS | ID: biblio-1057266

ABSTRACT

Abstract INTRODUCTION: Despite the success of antiretrovirals, human immunodeficiency virus (HIV) coinfections continue to cause mortality. We investigated the prevalence of coinfections in women with HIV/acquired immunodeficiency syndrome in Sergipe, Brazil. METHODS: We conducted a cross-sectional study. The coinfections investigated were syphilis, hepatitis B and C, toxoplasmosis, rubella, tuberculosis, and cytomegalovirus. RESULTS: Among the 435 women, 85 (19.5%) had coinfections. The most prevalent was HIV/syphilis, followed by tuberculosis, toxoplasmosis, hepatitis C, hepatitis B, and rubella. Additionally, 300 (96.2%) were seropositive for cytomegalovirus immunoglobulin G. CONCLUSIONS: Despite significant progress in the treatment for people with HIV, coinfections continued to affect this population.


Subject(s)
Humans , Female , Adolescent , Adult , Aged , Young Adult , Rubella/epidemiology , Tuberculosis/epidemiology , HIV Infections/epidemiology , Toxoplasmosis/epidemiology , Hepatitis C/epidemiology , Hepatitis B/epidemiology , Socioeconomic Factors , Brazil/epidemiology , Prevalence , Cross-Sectional Studies , Coinfection , Middle Aged
11.
Rev. Soc. Bras. Med. Trop ; 53: e20180533, 2020. tab
Article in English | LILACS | ID: biblio-1057270

ABSTRACT

Abstract INTRODUCTION: HBV and HIV have identical transmission routes. The aim of this study was to determine the prevalence of HBV in HIV patients and to detect the presence of occult HBV infection. METHODS: All samples were tested for serology markers and using qPCR. RESULTS: This study included 232 individuals, out of which 36.6% presented with HBV markers and 11.8% presented with HBsAg or HBV-DNA, including 3 patients that showed OBI. CONCLUSIONS: We observed a high prevalence of HBV among HIV patients. In addition, the results suggest that OBI can occur in patients with serological profiles that are indicative of past infection. Therefore, the application of molecular tests may enable the identification of infections that are not evident solely based on serology.


Subject(s)
Humans , HIV Infections/epidemiology , Hepatitis B virus/immunology , Hepatitis B/epidemiology , Hepatitis B Antibodies/blood , Hepatitis B Core Antigens/blood , Hepatitis B Surface Antigens/blood , Brazil/epidemiology , DNA, Viral/blood , HIV Infections/complications , Prevalence , Real-Time Polymerase Chain Reaction , Hepatitis B/complications , Hepatitis B/diagnosis
12.
Rev. Soc. Bras. Med. Trop ; 53: e20190559, 2020. tab
Article in English | ColecionaSUS, LILACS, ColecionaSUS, SES-SP | ID: biblio-1136898

ABSTRACT

Abstract INTRODUCTION: Brazil's western Amazon basin has the highest prevalence of hepatitis B virus (HBV) infection in the country. Coinfection with hepatitis D virus (HDV) is also endemic. To estimate the prevalence of HBV and HDV markers in a population inhabiting the northwest portion of Mato Grosso state in the western Amazon. METHODS: We performed a cross-sectional study of the seroprevalence of antibodies against HBV core antigen (anti-HBc) in the Três Fronteiras District northwest of Mato Grosso. Anti-HBc-positive subjects were tested for HBV surface antigen (HBsAg). Those positive for this marker were tested for HDV antibodies. Anti-HBc-negative participants were tested for anti-HBsAg. All tests were performed by EIA. RESULTS: A total of 623 individuals in the community were assessed; the majority (67.6%) were male, with a mean age of 30.8 ± 15.4 years. Two hundred and fourteen individuals (34.3%) were anti-HBc-positive, and 47 (7.5%) were HBsAg carriers. Only one individual was anti-HDV-positive. Among the 409 individuals without HBV infection, 18.3% were anti-HBsAg-positive. There was no association between HBV infection and known risk factors. CONCLUSIONS: The study area had intermediate-to-high endemicity for HBV infection, but a low prevalence of HDV. Our serological results suggesting low vaccination-induced protection indicate a need for reinforced immunization programs in the populations of northwest Mato Grosso.


Subject(s)
Humans , Male , Adolescent , Adult , Young Adult , Hepatitis B/epidemiology , Hepatitis D/epidemiology , Brazil/epidemiology , Seroepidemiologic Studies , Hepatitis B virus/immunology , Prevalence , Cross-Sectional Studies , Hepatitis B Antibodies , Hepatitis B Surface Antigens , Middle Aged
13.
Braz. j. infect. dis ; 23(6): 419-426, Nov.-Dec. 2019. tab
Article in English | LILACS | ID: biblio-1089319

ABSTRACT

ABSTRACT Introduction: Hepatitis B virus (HBV) is responsible for one of the most common human viral infections. An estimated 257 million people are living with chronic HBV infection worldwide, and mortality has reached 900,000 deaths in recent years. In 2001, the World Health Organization reported a prevalence of chronic hepatitis B infection in Iran between 2-7%. Objective: To assess the effect of the national HBV mass vaccination program after 25 years. Methods: A retrospective cohort study was conducted in vaccinated and unvaccinated people according to the year of birth. Blood samples were obtained from each enrolled person and data about demographic variables, and medical and vaccination history were collected using a standardized questionnaire. Persons were considered uninfected if they were negative for both HBsAg and anti-HBc. Also, Vaccine effectiveness was measured by calculating the risk of disease among vaccinated and unvaccinated persons and defining the percentage risk reduction of infection in the vaccinated group. Results: A total of 2720 persons were interviewed. The rate of HBV breakthrough infection among the vaccinated group was significantly lower than in unvaccinated group. One hundred ninety-four cases with positive HBV markers of infection were identified. The risk ratio of HBV infection was 0.71, 95% CI: 0.54-0.94 (vaccinated/unvaccinated). The estimated vaccination effectiveness against Hepatitis B infection was 29% (95% CI: 6%-46%). Conclusions: Iran has successfully combined hepatitis B vaccination into regular immunization programs. The WHO goal of reducing HBsAg prevalence to an equivalent of 1% by 2020 has been reached. With respect to vaccination effectiveness and low prevalence of the disease in the country, catch-up hepatitis B vaccination programs for adolescents can guarantee the immunity of the population.


Subject(s)
Humans , Male , Adolescent , Adult , Middle Aged , Young Adult , Vaccination/statistics & numerical data , Hepatitis B Vaccines/administration & dosage , Immunization Programs/statistics & numerical data , Hepatitis B, Chronic/prevention & control , Hepatitis B/prevention & control , Prevalence , Surveys and Questionnaires , Retrospective Studies , Hepatitis B, Chronic/immunology , Hepatitis B, Chronic/epidemiology , Hepatitis B/epidemiology , Iran/epidemiology
14.
Rev. bras. enferm ; 72(5): 1265-1270, Sep.-Oct. 2019. tab
Article in English | LILACS, BDENF | ID: biblio-1042147

ABSTRACT

ABSTRACT Objective: to analyze clinical, serological, biochemical and hematological aspects in patients infected with the hepatitis B (HBV) and Delta (HDV) viruses. Method: cross-sectional, descriptive and retrospective study, performed with patients chronically infected with HBV and superinfected with HDV. Results: among the 112 patients selected, 74% were monoinfected with HBV (Group HBV) and 26% were superinfected with HDV (Group HBV+HDV). There was no difference in gender distribution. The average age was 36 years with standard deviation of ±12 years. The symptoms and signs presented a higher proportion in Group HBV+HDV (p=0.001). In both groups, most patients had non-reactive AgHBe. The records of biochemical and hematologic changes showed highest proportion in Group VHB+VHD Group (p<0.05). Conclusion: the study found that patients were in clinical stages of the disease different from those in the initial examination for monitoring their chronic condition. The clinical profile suggests greater severity of liver disease among the patients superinfected with HDV.


RESUMEN Objetivo: Analizar los aspectos clínicos, serológicos, bioquímicos y hematológicos de pacientes infectados por el virus de las hepatitis B (VHB) y Delta (VHD). Método: Se trata de un estudio transversal, descriptivo, retrospectivo, realizado entre pacientes crónicos infectados de VHB y sobre infectados de VHD. Resultados: Entre los 112 pacientes seleccionados, el 74% estaba mono infectado por VHB (Grupo VHB) y el 26%, sobre infectado por VHD (Grupo VHB+VHD). No se encontró diferencia en la distribución por género. La edad promedio era 36 años, con desviación típica de ±12 años. Los síntomas y signos sobresalían en mayor proporción en el grupo VHB+VHD (p=0,001). Para ambos grupos, la mayoría de los pacientes estaba con AgHBe no reactivo. El registro de alteraciones bioquímicas y hematológicas atribuyó proporción más grande al grupo VHB+VHD (p<0,05). Conclusión: El estudio demostró que los pacientes, en la consulta inicial para el seguimiento de la condición crónica, estaban en diferentes estadios clínicos de la enfermedad. El perfil clínico sugiere que la gravedad de la enfermedad hepática es mayor entre pacientes sobre infectados de VHD.


RESUMO Objetivo: Analisar aspectos clínicos, sorológicos, bioquímicos e hematológicos entre pacientes infectados por vírus das hepatites B (VHB) e Delta (VHD). Método: Estudo transversal, descritivo, retrospectivo, realizado com pacientes cronicamente infectados por VHB e superinfectados por VHD. Resultados: Entre os 112 pacientes selecionados, 74% estavam monoinfectados por VHB (Grupo VHB) e 26% superinfectados por VHD (Grupo VHB+VHD). Não houve diferença na distribuição por gênero. A idade média foi de 36 anos, com desvio padrão de ±12 anos. Os sintomas e sinais apresentaram maior proporção no grupo VHB+VHD (p=0,001). Para ambos os grupos, a maioria dos pacientes estava com AgHBe não reagente. O registro de alterações bioquímicas e hematológicas apresentou maior proporção no grupo VHB+VHD (p<0,05). Conclusão: O estudo revelou que os pacientes estavam em diferentes estágios clínicos da doença na consulta inicial para acompanhamento de condição crônica. O perfil clínico sugere maior gravidade da doença hepática entre os pacientes superinfectados por VHD.


Subject(s)
Humans , Male , Female , Adult , Hepatitis D/classification , Hepatitis B/classification , Hepatitis D/epidemiology , Brazil/epidemiology , Hepatitis Delta Virus/classification , Hepatitis B virus/classification , Cross-Sectional Studies , Retrospective Studies , Hepatitis B/epidemiology , Middle Aged
15.
Rev. chil. infectol ; 36(5): 576-584, oct. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1058083

ABSTRACT

Resumen Introducción: Chile es un país de baja endemia de virus de hepatitis B (VHB), pero los países de mayor flujo migratorio hacia Chile tienen una endemia intermediaalta. La inmunoprofilaxis (IP) en el recién nacido (RN) es fundamental para evitar la transmisión vertical de VHB. Objetivos: Determinar la prevalencia de HBsAg en mujeres embarazadas: inmigrantes, y chilenas con conductas de riesgo (CR), y evaluar el cumplimiento de la indicación de IP a los RN de madre con HBsAg reactivo. Material y Métodos: Cohorte prospectiva de cribado de HBsAg a mujeres embarazadas inmigrantes, y chilenas con CR, entre julio 2017 y junio 2018 en CABL. Los RN de madre con HBsAg reactivo se les administró IP adecuada (antes de 12 h de vida). Resultados: Se realizó un total de 1.415 HBsAg: 1.265 a inmigrantes y 150 a chilenas con CR. Se obtuvieron 37 pacientes con HBsAg reactivos. Dos falsos positivos. La prevalencia HBsAg en inmigrantes fue 2,7% y 0,66% en chilenas con CR (p < 0,05). El 91,1% provenía de Haití, con una prevalencia de 3,5% en nuestra área. Todos los RN (36) recibieron IP. La mediana de administración de IP fue 3:02 h. Conclusiones: La prevalencia de VHB en mujeres gestantes inmigrantes fue superior a lo reportado en la población general y en mujeres chilenas con CR. Planteamos la necesidad de implementar el cribado universal en el embarazo, y en especial, en mujeres embarazadas provenientes de países con endemia intermedia-alta.


Background: Chile is a low-endemic HBV country, but countries with the highest migratory flow to Chile have an intermediate-high endemicity. In order to avoid vertical transmission of HBV, immunoprophylaxis (IP) in the newborn (NB) is a key factor. Aim: To identify HBsAg prevalence in pregnant immigrants and Chilean pregnant women with risk behaviors (RB) and to asses IP use in the NB. Material and Methods: Prospective HBsAg screening cohort of immigrant and Chilean pregnant women with RB, between July 1, 2017 and June 30, 2018 in CABL. IP of all NB of reactive HBsAg mothers was assessed. Results: 1,415 HBsAg samples, 1,265 immigrants and 150 Chileans with RB. 37 reactive HBsAg. Two false positive. HBsAg prevalence in immigrant pregnant women was 2.7% and 0.66% in Chileans with RB (p < 0.05). 91.1% came from Haiti, with a prevalence of 3.5% in our region. All NB (36) received IP with a median of administration of 3:02 h. Conclusions: The prevalence in immigrant pregnant women was higher than that reported in the general population and in Chilean women with RB. We proposed the need for universal screening in pregnancy, especially in pregnant women from countries with intermediate-high endemicity.


Subject(s)
Humans , Male , Female , Pregnancy , Infant, Newborn , Adult , Young Adult , Pregnancy Complications, Infectious/epidemiology , Mass Screening/methods , Infectious Disease Transmission, Vertical/prevention & control , Emigrants and Immigrants , Hepatitis B/transmission , Hepatitis B/epidemiology , Hepatitis B Surface Antigens/analysis , Pregnancy Complications, Infectious/virology , Risk-Taking , Time Factors , Seroepidemiologic Studies , Chile/epidemiology , Hepatitis B virus/isolation & purification , Prospective Studies , Risk Factors , Vaccination/methods
16.
Hematol., Transfus. Cell Ther. (Impr.) ; 41(3): 199-204, July-Sept. 2019. tab
Article in English | LILACS | ID: biblio-1039918

ABSTRACT

ABSTRACT Introduction: Carriers of oncohematological diseases are at high risk for hepatitis B virus (HBV) infection. Objective and method: To investigate the epidemiology of HBV infection in Goiânia, Central Brazil, 322 individuals with oncohematological diseases (leukemias, Hodgkin lymphoma and non-Hodgkin lymphoma) were interviewed and blood samples were collected for the detection of serological markers of HBV-DNA by polymerase chain reaction (PCR). Medical records of participants were also reviewed. Results: Non-Hodgkin's lymphomas (n = 99) and chronic myeloid leukemia (n = 108) were the most frequent oncohematological diseases. The overall prevalence of HBV was 13.97% (45/322). Of the total participants, 8.69% (28/322) presented isolated positivity for anti-HBs, suggesting low vaccine coverage. HBV-DNA was detected in 25% (1/4) of HBsAg positive samples and in 25% (3/12) of anti-HBc isolated, suggesting HBV occult infection. All samples were identified as subgenotype A1. Entries in patient records and the findings of this investigation suggest anti-HBc seroconversion during oncologic treatment. Age 50 years or over and use of a central catheter during therapy were associated with HBV exposure. Conclusion: The low frequency of hepatitis B immunized individuals, detection of HBV DNA in HBsAg negative samples, and the suggestion of HBV exposure during treatment evidenced the potential for health-related viral dissemination in people with oncohematological diseases in our region, reinforcing the importance of serological monitoring, vaccination against hepatitis B, and adoption of strict infection control measures in these individuals.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Lymphoma, Non-Hodgkin , Leukemia , Hepatitis B/epidemiology , Lymphoma , Medical Oncology
17.
Rev. cuba. med. gen. integr ; 35(3): e417, jul.-set. 2019. tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1093507

ABSTRACT

Introducción: La hepatitis B es un problema de salud a nivel mundial; los estudiantes de ciencias de la salud deben tener pleno conocimiento de dicha enfermedad, no solo como parte de su aprendizaje, sino porque se encuentran expuestos a accidentes ocupacionales y mayor riesgo de transmisión en la práctica. Objetivo: Evaluar el nivel de conocimientos sobre hepatitis B en estudiantes de ciencias de la salud y los factores asociados a este nivel de conocimientos. Métodos: Estudio transversal, analítico; realizado en una Facultad Peruana de Ciencias de la Salud. Evaluamos el nivel de conocimientos a través de un cuestionario de 20 preguntas sobre la infección con hepatitis B, se recolectaron datos socio-educativos y preventivos de los estudiantes sobre hepatitis B. La variable analítica fue el tener mejor conocimiento (tercil superior). Se hallaron razones de prevalencias en el programa estadístico Stata. Resultados: De los 205 estudiantes de medicina, odontología y tecnología médica, 57 por ciento fueron mujeres, predominantemente de primer año (39 por ciento). La media del puntaje fue 12 puntos (rango intercuartílico: 10-13), de 20 puntos posibles. Encontramos que el 82 por ciento manifestó tener la vacunación incompleta. Los estudiantes de las áreas clínicas tuvieron mayor probabilidad de obtener una evaluación satisfactoria (RP: 1,84; IC95 por ciento:1,06-3,18). Conclusiones: La mayoría de estudiantes tuvo un inadecuado nivel de conocimientos sobre hepatitis B, siendo los estudiantes de ciencias clínicas los que tuvieron mejores resultados. Por tal motivo, sugerimos a las autoridades tomar medidas oportunas para corregir esta situación, por ser una población de alto riesgo de infección(AU)


Introduction: Hepatitis B is a global health problem; Health science students should be fully aware of this pathology, not only as part of their learning, but because they are exposed to occupational accidents and increased risk of transmission in practice. The aim of the study was to assess the level of knowledge about Hepatitis B in health science students and to determine the factors associated with this level of knowledge. Methodology: Cross-sectional, analytical study; performed in peruvian health sciences faculty. Knowledge was evaluated with a questionnaire of 20 questions about Hepatitis B infection. Likewise, socio-educational and preventive data were collected from students about hepatitis B. The analytical variable was to have the better knowledge (upper tertile). Prevalence ratios were found in the statistical program Stata. Results: Of the 205 students to medicine, dentistry and medical technology, 57 percent were women, predominantly in the first year (39 percent). The mean of the score was 12 points (interquartile range: 10-13), of 20 possible points. We found that 82 percent reported incomplete vaccination. The students in the clinical areas were more likely to obtain a satisfactory evaluation. (PR: 1.84, 95 percent CI: 1.06-3.18). Conclusions: Most students had an inadequate level of knowledge about Hepatitis B, being the clinical sciences students who did better results. For this reason, we suggest that the authorities take appropriate measures to correct this situation, as a population at high risk of infection(AU)


Subject(s)
Humans , Male , Female , Hepatitis B Vaccines , Knowledge , Hepatitis B/epidemiology , Cross-Sectional Studies
18.
Buenos Aires; GCBA. Gerencia Operativa de Epidemiología; 24 mayo 2019. a) f: 12 l:19 p. tab, graf.(Boletín Epidemiológico Semanal: Ciudad Autónoma de Buenos Aires, 4, 144).
Monography in Spanish | LILACS, InstitutionalDB, BINACIS, UNISALUD | ID: biblio-1102803

ABSTRACT

Se describe la modalidad de presentación y notificación de los casos de infecciones de transmisión vertical que fueron reportados a la División de Promoción y Protección (P y P) desde los Servicios del Hospital Argerich de la Ciudad de Buenos Aires, y los efectores de su Área Programática, entre la Semana Epidemiológica (SE) 1 y 52 del trienio 2016-2018, con el propósito de mejorar el proceso de diagnóstico-notificación-atención-cuidado (PDNAC) y seguimiento de los casos de ITS y transmisión vertical atendidos en el hospital. Para esto, se realizó un estudio descriptivo con los datos de los casos de sífilis en población general y en embarazadas, sífilis congénita, hepatitis B en embarazadas y recién nacidos, VIH en embarazadas y VIH expuesto perinatal, enfermedad de Chagas en embarazada y congénita notificados a la División de PyP.


Subject(s)
Syphilis/epidemiology , Sexually Transmitted Diseases/epidemiology , HIV , Chagas Disease/epidemiology , Infectious Disease Transmission, Vertical/prevention & control , Infectious Disease Transmission, Vertical/statistics & numerical data , Disease Notification/methods , Hepatitis B/epidemiology , Preventive Health Services , Hospitals, Municipal
19.
Rev. chil. infectol ; 36(2): 221-233, abr. 2019. tab
Article in Spanish | LILACS | ID: biblio-1003668

ABSTRACT

Resumen Las infecciones de transmisión sexual (ITS) son una de las principales causas de enfermedad aguda, infertilidad, discapacidad a largo plazo y muerte en el mundo1. Este informe presenta la situación epidemiológica preliminar de las ITS hasta el año 2017 en Chile. Sífilis es la ITS de mayor tasa de notificación, seguido de la infección por VIH. En términos generales, todas las ITS presentan una relativa estabilización de sus tasas en el período 2014 y 2015, excepto gonorrea que muestra un incremento en estos años, el que se focaliza en el grupo de 15 a 24 años. El año 2017, sífilis y la infección por VIH presentaron un aumento de sus tasas en relación al año 2016. En todas estas ITS la tasa de hombres supera a la de mujeres y el grupo de edad más afectado es el de 15 a 39 años. Según distribución geográfica, las regiones de Arica-Parinacota a Antofagasta, Metropolitana, Valparaíso, Los Lagos y Aysén, presentan los mayores riesgos.


Sexually transmitted infections (STIs) are one of the main causes of acute illness, infertility, long-term disability and death in the world1. This report presents the preliminary epidemiological situation of STIs up to the year 2017 in Chile. Syphilis is the STI with the highest reporting rate, followed by HIV infection. In general terms, all STIs present a relative stabilization of their rates in the 2014 and 2015 periods, except for gonorrhea that shows an increase in these years, which focuses on the group of 15 to 24 years. In 2017, syphilis and HIV infection showed an increase in their rates in relation to 2016. In all these STIs the rate of men exceeds that of women and the most affected age group is 15 to 39 years. According to geographical distribution, the regions of Arica-Parinacota to Antofagasta, Metropolitana, Valparaíso, Los Lagos and Aysén, present the greatest risks.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Gonorrhea/epidemiology , Syphilis/epidemiology , HIV Infections/epidemiology , Disease Notification/statistics & numerical data , Hepatitis B/epidemiology , Time Factors , Chile/epidemiology , Prevalence , Sex Distribution , Age Distribution
20.
Rev. bras. epidemiol ; 22: e190004, 2019. tab, graf
Article in English | LILACS | ID: biblio-990748

ABSTRACT

ABSTRACT: Introduction: This paper details the methods used in the second national Biological and Behavioral Surveillance Survey (BBSS) of HIV, syphilis, and hepatitis B and C among men who have sex with men in Brazil. Methods: Respondent-driven sampling (RDS) was used in 12 cities in 2016. The targeted sample size was initiated with five to six seeds in each city. HIV, syphilis, and Hepatitis B and C rapid tests were offered to participants. RDS Analyst with Gile's successive sampling (SS) estimator was used to adjust results as recommended and a weight for each individual was generated for further analysis. Data for the 12 cities were merged and analyzed using Stata 14.0 complex survey data tools with each city treated as its own stratum. Results: Duration of data collection varied from 5.9 to 17.6 weeks. 4,176 men were recruited in the 12 cities. Two sites failed to achieve targeted sample size due to a six-month delay in local IRB approval. No city failed to reach convergence in our major outcome variable (HIV). Conclusion: The comprehensive BBSS was completed as planned and on budget. The description of methods here is more detailed than usual, due to new diagnostic tools and requirements of the new STROBE-RDS guidelines.


RESUMO: Introdução: Este artigo detalha os métodos utilizados na segunda Pesquisa Nacional de Vigilância Biológica e Comportamental (BBSS) do HIV, sífilis e hepatite B e C entre os homens que fazem sexo com homens no Brasil. Métodos: O método Respondent-driven Sampling (RDS) foi utilizado em 12 cidades em 2016. A amostra foi iniciada com cinco a seis sementes em cada cidade. Testes rápidos para o HIV, sífilis e Hepatite B e C foram oferecidos aos participantes. O software RDS Analyst com o estimador de amostragem sucessiva (SS) de Gile foi utilizado para ajustar os resultados como recomendado, gerando um peso para cada indivíduo para análises. Osdados das 12cidades foram unidos em um único banco e analisados usando as ferramentas de dados complexos do Stata 14.0, com cada cidade sendo tratada como seu próprio estrato. Resultados: A duração da coleta de dados variou de 5,9 a 17,6 semanas e 4.176 homens foram recrutados nas 12 cidades. Dois sites não alcançaram o tamanho da amostra alvo devido a uma demora de seis meses na aprovação local do Comitê de Ética. Todas as cidades atingiram a convergência na principal variável estudada (HIV). Conclusão: O BBSS foi representativo e concluído conforme planejado e dentro do orçamento. A descrição dos métodos aqui é mais detalhada do que o habitual, devido às novas ferramentas e requisitos de diagnóstico das novas diretrizes do STROBE-RDS.


Subject(s)
Humans , Male , Adult , Syphilis/diagnosis , HIV Infections/diagnosis , Hepatitis C/diagnosis , Homosexuality, Male/statistics & numerical data , Hepatitis B/diagnosis , Brazil/epidemiology , Syphilis/epidemiology , HIV Infections/epidemiology , Population Surveillance , Prevalence , Surveys and Questionnaires , Health Surveys/methods , Hepatitis C/epidemiology , Self Report , Hepatitis B/epidemiology
SELECTION OF CITATIONS
SEARCH DETAIL