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1.
Semina cienc. biol. saude ; 43(1): 177-184, jan./jun. 2022.
Article in Portuguese | LILACS | ID: biblio-1354485

ABSTRACT

Objetivo: explorar a percepção de um paciente cirúrgico queimado em relação à sede e seu manejo no período pré-operatório e pós-operatório imediato. Relato de caso: trata-se de um estudo com abordagem qualitativa, exploratória, do tipo estudo de caso. Os critérios de inclusão foram: paciente estar internado no centro de tratamento de queimados, ser submetido a procedimento cirúrgico ou balneoterapia, ter experenciado a sede no período pré-operatório ou pós-operatório e ter recebido o manejo da sede. Para a coleta de dados utilizou-se entrevista semiestruturada, gravada e transcrita. Paciente do sexo feminino, de 32 anos, admitida com queimaduras de segundo grau em extensão de tórax, membros superiores e pescoço por tentativa de autoextermínio com álcool. Passou por seis procedimentos e esteve internada por 15 dias até o momento da coleta. Experienciou o desconforto sede durante o jejum pré-operatório e pós-operatório, considerado intenso e muito estressante durante sua internação. Conclusão: a partir da identificação do desconforto sede, utilizou-se como estratégia o picolé de gelo, que fez diferença em seu tratamento. O modelo de manejo da sede é pioneiro no cuidado ao paciente queimado e apresenta benefícios para minorar a sede.


Objective: explore thirst perception of a burnt surgical patient and its management in the preoperative and immediate postoperative period. Case report: study with a qualitative and exploratory approach, named as case study. Inclusion criteria were: inpatient at burnt treatment unit, undergone surgical procedure or balneotherapy, experienced thirst in the preoperative or postoperative period and received thirst management. For data collection, semi-structured interviews were performed, recorded and transcribed. Female patient, 32 years old, admitted with second degree burns in extension of thorax, upper limbs and neck due to attempted self-extermination with alcohol. Underwent six procedures and was hospitalized for 15 days until the data collection. Experienced thirst discomfort during preoperative and postoperative fasting, which was considered intense and very stressful during his hospitalization. Conclusion: since the identification of thirst discomfort, the ice popsicle was used as a strategy, which made difference in her treatment. The thirst management model is pioneer in care of burnt patients and has benefits to alleviate thirst.


Subject(s)
Humans , Female , Adult , Patients , Thirst , Balneology , Burns , Ice , Postoperative Period , Therapeutics , Data Collection , Fasting , Preoperative Period , Hospitalization , Inpatients , Neck
3.
J. Phys. Educ. (Maringá) ; 31: e3101, 2020. tab, graf
Article in English | LILACS | ID: biblio-1098329

ABSTRACT

ABSTRACT The ice application (cooling) has become popular during physical activities to improve performance. This study aimed to test whether different cooling places could increase the number of repetitions (volume) during resistance training with blood flow restriction (BFR). Ten women volunteered for this study. The sample characterization is presented in mean and standard deviation: age: 28.5 ± 8.6 years; height: 164.6 ± 8.3 cm; total body mass: 61.5 ± 7.1 maximal dynamic strength test (1RM): 236.5 ± 54.8 kg; 30% 1RM: 71.6 ± 16.5; SBP: 124.7 ± 7.7 mm Hg; 1.3 x SBP: 161.8 ± 10.4 mm Hg. The subjects performed five sessions of resistance exercise with BFR. Three sets were held in each session, with the intensity of 30% of 1RM until muscle failure; and 30-second rest period between sets. The cooling sites were: hands, neck, and tunnel temperature. One session without cooling was done and considered as a control group. There was neither difference in the total number of repetitions of repetitions among interventions, nor a significant difference among interventions for RPE (P = 0.49). Therefore, we do not recommend cooling to maintain a high number of repetitions during strength training with BFR.


RESUMO A aplicação do gelo (resfriamento) tem sido uma estratégia popular durante as atividades físicas para aumentar o desempenho. O objetivo deste estudo foi testar se diferentes locais de resfriamento podem aumentar o número de repetições (volume) durante o treinamento resistido com restrição do fluxo sanguíneo (RFS). Dez mulheres se voluntariaram para este estudo. A caracterização da amostra é apresentada em média e desvio padrão: idade: 28,5 ± 8,6 anos; estatura: 164,6 ± 8,3 cm; massa corporal total: 61,5 ± 7,1; teste de força muscular dinâmica (1RM): 236,5 ± 54,8kg; 30% 1RM: 71,6 ± 16,5; PAS: 124,7 ± 7,7 mm Hg; 1,3 x PAS: 161,8 ± 10,4 mmHg, participaram do estudo. Os sujeitos realizaram cinco sessões de exercício resistido com RFS. Três séries foram realizadas em cada sessão, com a intensidade de 30% de 1RM até falha muscular e 30 segundos de descanso entre as séries. Os locais de resfriamento foram: mãos, pescoço e temperatura do túnel. Uma sessão sem resfriamento foi realizada e considerada como grupo controle. Não houve diferença no número total de repetições entre as intervenções, nem diferença entre as intervenções para percepção subjetiva de esforço (P = 0,49). Portanto, nós não recomendamos o resfriamento para manter um alto número de repetições durante o treinamento de força com restrição do fluxo sanguíneo.


Subject(s)
Humans , Female , Adult , Time , Blood Circulation , Cold Temperature/methods , Resistance Training , Body Weight , Exercise , Athletic Performance , Arterial Pressure , Ice
5.
Asia Pacific Allergy ; (4): e3-2019.
Article in English | WPRIM | ID: wpr-750171

ABSTRACT

Anhidrotic ectodermal dysplasia (AED) is a rare hereditary disorder with a triad of sparse hair, dental hypoplasia, and anhidrosis. Here we report a case of AED with food allergy and atopic eczema. The patient was a 11-month-old boy admitted to our hospital with pyrexia for 2 weeks. He presented with a history of dry skin, eczema, and food allergy to egg. On clinical examination, his body temperature was 38.8°C, with dry skin and eczema almost all over the body, sparse eyebrows, and scalp hair. Laboratory investigations and physical examination did not show any evidence of infection. Radioallergosorbent test was positive to egg yolk, egg white, ovomucoid, milk, house dust, and house dust mite. As the child did not sweat despite the high fever, we performed the sweat test which revealed a total lack of sweat glands. Genetic examination revealed a mutation of the EDA gene and he was diagnosed as AED. His pyrexia improved upon cooling with ice and fan. His mother had lost 8 teeth and her sweat test demonstrated low sweating, suggestive of her being a carrier of AED. Atopy and immune deficiencies have been shown to have a higher prevalence in patients with AED. Disruption of the skin barrier in patients with AED make them more prone to allergic diseases such as atopic eczema, bronchial asthma, allergic rhinitis and food allergy. Careful assessment of the familial history is essential to differentiate AED when examining patients with pyrexia of unknown origin and comorbid allergic diseases.


Subject(s)
Asthma , Body Temperature , Child , Dermatitis, Atopic , Dust , Ectodermal Dysplasia , Eczema , Egg White , Egg Yolk , Eyebrows , Fever , Food Hypersensitivity , Hair , Humans , Hypohidrosis , Ice , Infant , Male , Milk , Mothers , Ovomucin , Ovum , Physical Examination , Prevalence , Pyroglyphidae , Radioallergosorbent Test , Rhinitis, Allergic , Scalp , Skin , Sweat , Sweat Glands , Sweating , Tooth
6.
Article in English | WPRIM | ID: wpr-762140

ABSTRACT

PURPOSE: To review the clinical features and natural courses of cold urticaria (ColdU) in a tropical country. METHODS: A retrospective chart review was performed of patients who visited Siriraj Urticaria Clinic, Siriraj Hospital, Bangkok, Thailand, and were diagnosed with ColdU between 2007 and 2018. Data on provocation and threshold tests, clinical courses, and laboratory work-up were analyzed and compared with data reported by studies in temperate countries. RESULTS: Of 1,063 chronic urticaria patients, 27 (2.5%) were diagnosed with ColdU, with a mean age of symptom onset of 34.8 years. Half of the patients had a history of atopy, and 1 (3.7%) had a history of anaphylaxis. All patients were positive to 1 of 3 provocation tests: an ice cube test; TempTest 4.0; or a tray filled with ice, salt and water. Thirteen patients underwent the ice cube test, and all had positive results. TempTest was performed on 15 patients, 8 of whom had positive results, with a mean critical temperature threshold (CTT) of 21.0°C. All of the 7 patients who had a negative TempTest result later produced positive results to the immersion of their hand and forearm in a tray filled with ice, salt, and water. All patients were treated with H1-antihistamines, the vast majority (96.3%) being non-sedating H1-antihistamines. Some (14.8%) needed to be administered oral corticosteroids, ciclosporin, or omalizumab. Six patients (22.2%) were in remission. A Kaplan-Meier survival curve demonstrated 5-year and 10-year remission rates of 13.8% and 42.6%, respectively. CONCLUSIONS: The rate of anaphylaxis in patients with ColdU in a tropical country was lower than those reported by other studies conducted intemperate climates. On the other hand, the number of female patients, mean age at symptom onset, atopy rate, rate of concomitant chronic spontaneous urticaria and mean CTT were higher.


Subject(s)
Adrenal Cortex Hormones , Anaphylaxis , Climate , Cyclosporine , Female , Forearm , Hand , Humans , Ice , Immersion , Omalizumab , Retrospective Studies , Thailand , Tropical Climate , Urticaria , Water
7.
Article in Korean | WPRIM | ID: wpr-761833

ABSTRACT

PURPOSE: To investigate the alteration of lower extremity movement during maintaining balance test with their eyes closed in chronic ankle instability (CAI) patients compared to healthy group with and without plantar cutaneous sensation. METHODS: Ten healthy volunteers (age, 23.40±2.22 years; height, 165.42±6.67 cm; weight, 60.93±13.42 kg) and 10 CAI patients (age, 23.90±2.56 years; height, 166.89±10.50 cm; weight, 67.43±12.96 kg), were recruited. Subjects immersed both feet in an ice water for 10 minutes and performed three trials of a single-leg stance balance test with their eyes closed while standing on a force plate for 10 seconds. RESULTS: CAI group showed increased knee flexion, reduced knee external rotation, and hip internal rotation compared to the healthy group from single-limb stance with eyes closed after diminished plantar cutaneous sensation. However, there was no significant interaction between group and time. CONCLUSION: These findings indicate that the postural kinematic analyses revealed that individuals with CAI used different strategy of controlling their lower extremities, which alters transverse plane motion of hip and knee compared to the healthy group in order to compensate for their ankle deficits after freezing the plantar cutaneous.


Subject(s)
Ankle , Foot , Freezing , Healthy Volunteers , Hip , Humans , Ice , Knee , Lower Extremity , Sensation , Water
8.
Safety and Health at Work ; : 219-223, 2019.
Article in English | WPRIM | ID: wpr-761349

ABSTRACT

BACKGROUND: Ice cooling vests can cause tissue damage and have no flexibility. Therefore, these two undesirable properties of ice cooling vest were optimized, and the present study was aimed to compare the impact of the optimized ice cooling vest and a commercial paraffin cooling vest on physiological and perceptual strain under controlled conditions. METHODS: For optimizing, hydrogel was used to increase the flexibility and a layer of the ethylene vinyl acetate foam was placed into the inside layer of packs to prevent tissue damage. Then, 15 men with an optimized ice cooling vest, with a commercial paraffin cooling vest, and without a cooling vest performed tests including exercise on a treadmill (speed of 2.8 km/hr and slope of %0) under hot (40℃) and dry (40 %) condition for 60 min. The physiological strain index and skin temperature were measured every 5 and 15 minutes, respectively. The heat strain score index and perceptual strain index were also assessed every 15 minutes. RESULTS: The mean values of the physiological and perceptual indices differed significantly between exercise with and without cooling vests (P 0.05). CONCLUSIONS: The optimized ice cooling vest was as effective as the commercial paraffin cooling vest to control the thermal strain. However, ice has a greater latent heat and less production cost.


Subject(s)
Exercise , Hot Temperature , Humans , Hydrogels , Ice , Male , Paraffin , Pliability , Skin Temperature
9.
Article in English | WPRIM | ID: wpr-715691

ABSTRACT

BACKGROUND AND PURPOSE: The various tests that are routinely used to diagnose generalized myasthenia gravis, such as the edrophonium test, serum anti-acetylcholine-receptor antibodies (AChR-Ab), and repetitive nerve stimulation (RNS) tests, have lower diagnostic sensitivity in ocular myasthenia gravis (OMG). Diagnosing OMG becomes even more difficult when the clinical symptoms are subtle. There is no gold-standard diagnostic test available for OMG patients, and so this study compared the diagnostic sensitivity of gaze photographs with conventional tests in OMG. METHODS: Records of gaze photographs were available for 25 of 31 consecutive patients diagnosed with OMG. Each patient underwent a neuro-ophthalmologic examination, serum AChR-Ab, RNS, edrophonium test, ice tests, and the acquisition of gaze photographs. The margin reflex distance 1 (MRD1) was measured on each of the gaze photographs, with MRD1 < 2 mm or an interlid MRD1 difference of ≥2 mm on any of the gaze photographs defined as a positive sign of OMG. The diagnostic sensitivities of the tests were assessed. RESULTS: The mean age at onset was 38.5 years (range, 2–76 years), and 13 patients (52%) were men. The diagnostic sensitivities of the RNS test, AChR-Ab test, gaze photographs, and ice test were 56%, 64%, 80%, and 73%, respectively. CONCLUSIONS: The diagnostic sensitivity was higher for gaze photographs than for the other tests applied to OMG patients.


Subject(s)
Age of Onset , Antibodies , Diagnosis , Diagnostic Tests, Routine , Edrophonium , Humans , Ice , Male , Myasthenia Gravis , Reflex
11.
Article in Korean | WPRIM | ID: wpr-718366

ABSTRACT

Acute lateral ankle sprain, which is the most common musculoskeletal injury, can be treated effectively with appropriate evidence-based initial care using PRICE (protection, rest, ice, compression, and elevation) and functional rehabilitation. Many systemic reviews reporting a high-level of evidence supporting the clinical usefulness and necessity of primary surgical repair for acute lateral ankle sprain have been insufficient. Regardless of the severity of ligament complex injuries, the surgical treatment for acute lateral ankle sprain without concomitant pathologies is not recommended and should be considered only in young professional athletes with complete ligament rupture (grade III) and severe instability.


Subject(s)
Ankle Injuries , Ankle , Athletes , Humans , Ice , Ligaments , Pathology , Rehabilitation , Rupture , Sprains and Strains
12.
Article in English | WPRIM | ID: wpr-741359

ABSTRACT

PURPOSE: Although the prognosis is generally good in patients with intermediate-risk neuroblastoma, no consensus has been reached on the ideal treatment regimen. This study analyzed treatment outcomes and toxicities in patients younger than 18 months with stage 4 MYCN nonamplified neuroblastoma. METHODS: We retrospectively analyzed 20 patients younger than 18 months newly diagnosed with stage 4 MYCN nonamplified neuroblastoma between January 2009 and December 2015. Patients received 9 cycles of chemotherapy and surgery, with or without local radiotherapy, followed by 12 cycles of differentiation therapy with 13-cis-retinoic acid. Chemotherapy consisted of alternating cycles of cisplatin, etoposide, doxorubicin, and cyclophosphamide (CEDC) and ifosfamide, carboplatin, and etoposide (ICE) regimens. RESULTS: The most common primary tumor site was the abdomen (85%), and the most common metastatic sites were the lymph nodes (65%), followed by the bones (60%), liver (55%), skin (45%), and bone marrow (25%). At the end of induction therapy, 14 patients (70%) achieved complete response, with 1 achieving very good partial response, 4 achieving partial response, and 1 showing mixed response. Nine patients (45%) received local radiotherapy. At a median follow-up of 47 months (range, 17–91 months), none of these patients experienced relapse, progression, or secondary malignancy, or died. Three years after chemotherapy completion, none of the patients had experienced grade ≥3 late adverse effects. CONCLUSION: Patients younger than 18 months with stage 4 MYCN nonamplified neuroblastoma showed excellent outcomes, without significant late adverse effects, when treated with alternating cycles of CEDC and ICE, followed by surgery and differentiation therapy.


Subject(s)
Abdomen , Bone Marrow , Carboplatin , Child , Cisplatin , Consensus , Cyclophosphamide , Doxorubicin , Drug Therapy , Etoposide , Follow-Up Studies , Humans , Ice , Ifosfamide , Infant , Isotretinoin , Liver , Lymph Nodes , Neoplasm Metastasis , Neuroblastoma , Prognosis , Radiotherapy , Recurrence , Retrospective Studies , Skin
13.
Article in English | WPRIM | ID: wpr-764448

ABSTRACT

Clinical reasoning (CR) is a key learning domain for physical therapy educators and a core skill for entry-level practitioners. Integrated clinical experience (ICE) and problem-based learning (PBL) have each been reported to improve interpersonal and social domains, while promoting knowledge acquisition and CR. Unfortunately, studies monitoring CR during ICE with concurrent PBL in physical therapy education are sparse. We hypothesized that ICE with concurrent PBL would be associated with improved self-reported CR in third-year student physical therapists (PTs) in the United States. The Self-Assessment of Clinical Reflection and Reasoning (SACRR) survey was administered to 42 student PTs at the beginning and end of their third and final year of didactic training. Between the pretest and posttest analyses, the participants completed faculty-led ICE and PBL coursework for 16 weeks. The overall SACRR score and 26 individual item scores were examined. The Wilcoxon rank-sum test and paired t-test were used, with statistical significance accepted at P < 0.05. Significant improvements were observed in the overall SACRR score (P < 0.001), including 6 of the 26 survey items centered around decision-making based on experience and evidence, as well as self-reflection and reasoning. ICE with PBL was associated with improved self-assessed CR and reflection in third-year student PTs in the United States. Monitoring the impact of curricular design on CR may improve educators' ability to enhance cognitive and psychomotor skills, which underscores the importance of increasing the explicit use of theoretical frameworks and teaching techniques for coping with uncertainty as a way of enhancing entry-level training.


Subject(s)
Education , Humans , Ice , Learning , Physical Therapists , Problem-Based Learning , Self-Assessment , Uncertainty , United States
14.
Article in English | WPRIM | ID: wpr-716788

ABSTRACT

Patients complaining of swelling and hematoma caused by contusion of the face can be easily seen in the emergency room. Most of the treatments were conservative treatments such as ice bag application, mild compression dressing, and massage. During the follow-up, fibrosis progression due to hematoma was frequently observed in the contusion site. When hematoma or fibrosis is confirmed, hyaluronidase (H-lase) 1,500 IU and 2 mL of normal saline were mixed and subcutaneously injected in crisscross manner. To evaluate the improvement of hematoma before and after hyaluronidase injection, three plastic surgeons evaluated using the Vancouver scar scale and compared preoperative and postoperative images. Hematoma and fibrosis after facial trauma improved after hyaluronidase injection for early treatment.


Subject(s)
Bandages , Cicatrix , Contusions , Emergency Service, Hospital , Fibrosis , Follow-Up Studies , Hematoma , Humans , Hyaluronic Acid , Hyaluronoglucosaminidase , Ice , Massage , Plastics , Surgeons
15.
Article in English | WPRIM | ID: wpr-8209

ABSTRACT

We present the first reported case of cold urticaria, which was mistaken as congestion status, in a patient undergoing breast reconstruction with deep inferior epigastric perforator (DIEP) flap coverage. A 53-year-old woman underwent an immediate bilateral breast reconstruction with DIEP flap coverage. The harvested DIEP flap was wrapped with wet gauze and kept above an ice pack to minimize ischemic damage before flap in-setting to the mastectomy site. After the transfer of the harvested DIEP flap, she had suddenly developed an erythematous and edematous lesion, specifically on the flap. The room temperature was raised and a single dose of steroid and antihistamine was given intravenously. At the first instance, flap congestion was suspected; however, as the rash gradually spread throughout the body, we could deduce that it was cold urticaria. The erythematous rash and whirl resolved soon after receiving medication. Patients with known cold urticaria undergoing surgical procedures require several precautions (e.g., antihistamine, relatively warm operation room) to lessen the risk of severe reaction. Especially in patients with DIEP free flap, the lack of preoperative treatment could result in a pinkish flap due to urticaria, which could be mistaken by the surgeon as a congested flap.


Subject(s)
Breast , Estrogens, Conjugated (USP) , Exanthema , Female , Free Tissue Flaps , Humans , Hyperemia , Ice , Mammaplasty , Mastectomy , Middle Aged , Urticaria
16.
Article in English | WPRIM | ID: wpr-203198

ABSTRACT

A survey was performed to know the recent infection status of digenetic trematode metacercariae in clams and oysters from 4 sites in western coastal regions of the Republic of Korea (=Korea). Four species of clams (Mactra veneriformis, Ruditapes philippinarum, Cyclina sinensis, and Saxidomus purpuratus) were collected from Taean-gun, Chungcheongnam-do (Province), Buan-gun (County) and Gochang-gun, Jeollabuk-do, and oysters, Crassostrea gigas, from Shinan-gun, Jeollanam-do were transferred to our laboratory on ice and examined by the artificial digestion method. The metacercariae of Himasthla alincia were detected in 3 species of clams, M. veneriformis, R. philippinarum, and C. sinensis from the 3 surveyed areas. The positive rate and the mean density per clam infected were 98.9% (30.8 metacercariae) in M. veneriformis, 60.0% (5.0) in R. philippinarum, and 96.0% (28.4) in C. sinensis. The positive rate (mean density) of Acanthoparyphium tyosenense metacercariae in M. veneriformis was 50.0% (2.1) from Taean-gun and 70.0% (2.8) from Gochang-gun. The metacercariae of Parvatrema spp. were detected in M. veneriformis and R. philippinarum from Taean-gun and Gochang-gun; the positive rate (mean density) was 63.3% (4,123) and 50.0% (19) in M. veneriformis, and 6.7% (126) and 100% (238) in R. philippinarum from the 2 regions, respectively. The metacercariae of Gymnophalloides seoi were detected in all 30 oysters from Shinan-gun, and their average density per oyster was 646. From the above results, it has been confirmed that more than 3 species of metacercariae are prevalent in clams from the western coastal regions, and G. seoi metacercariae are still prevalent in oysters from Shinan-gun, Jeollanam-do, Korea


Subject(s)
Bivalvia , Crassostrea , Digestion , Ice , Korea , Metacercariae , Methods , Ostreidae , Prevalence , Republic of Korea , Trematoda
17.
Article in English | WPRIM | ID: wpr-25855

ABSTRACT

PURPOSE: The purpose of this study was to investigate the electrochemical characteristics of nanotubular Ti-25Nb-xZr ternary alloys for dental implant materials. MATERIALS AND METHODS: Ti-25Nb-xZr alloys with different Zr contents (0, 3, 7, and 15 wt.%) were manufactured using commercially pure titanium (CP-Ti), niobium (Nb), and zirconium (Zr) (99.95 wt.% purity). The alloys were prepared by arc melting in argon (Ar) atmosphere. The Ti-25Nb-xZr alloys were homogenized in Ar atmosphere at 1,000℃ for 12 hours followed by quenching into ice water. The microstructure of the Ti-25Nb-xZr alloys was examined by a field emission scanning electron microscope. The phases in the alloys were identified by an X-ray diffractometer. The chemical composition of the nanotube-formed surfaces was determined by energy-dispersive X-ray spectroscopy. Selforganized TiO₂ was prepared by electrochemical oxidation of the samples in a 1.0 M H₃PO₄+0.8 wt.% NaF electrolyte. The anodization potential was 30 V and time was 1 hour by DC supplier. Surface wettability was evaluated for both the metallographically polished and nanotube-formed surfaces using a contact-angle goniometer. The corrosion properties of the specimens were investigated using a 0.9 wt.% aqueous solution of NaCl at 36℃±5℃ using a potentiodynamic polarization test. RESULT: Needle-like structure of Ti-25Nb-xZr alloys was transform to equiaxed structure as Zr content increased. Nanotube formed on Ti-25Nb-xZr alloys show two sizes of nanotube structure. The diameters of the large tubes decreased and small tubes increased as Zr content increased. The lower contact angles for nanotube formed Ti-25NbxZr alloys surfaces showed compare to non-nanotube formed surface. The corrosion resistance of alloy increased as Zr content increased, and nanotube formed surface showed longer the passive regions compared to non-treatment surface. CONCLUSION: It is confirmed that corrosion resistance of alloy increased as Zr content increased, and nanotube formed surface has longer passive region compared to without treatment surface.


Subject(s)
Alloys , Argon , Atmosphere , Corrosion , Dental Implants , Freezing , Ice , Nanotubes , Niobium , Spectrum Analysis , Titanium , Water , Wettability , Zirconium
18.
Article in English | WPRIM | ID: wpr-25541

ABSTRACT

The purpose of this study was to investigate the immunomodulatory activity of ice plant (Mesembryanthemum crystallinum) extract (IPE) in vitro and in vivo. Raji (a human B cell line) and Jurkat (a human T cell line) cells were treated with various doses of IPE and cell proliferation was measured by WST assay. Results showed that IPE promoted the proliferation of both Raji and Jurkat cells in a dose-dependent manner. IPE also enhanced IL-6 and TNF-α production in macrophages in the presence of lipopolysaccharide (LPS), although IPE alone did not induce cytokine production. Moreover, IPE treatment upregulated iNOS gene expression in macrophages in a time- and dose-dependent manner and led to the production of nitric oxide in macrophages in the presence of IFNγ. In vivo studies revealed that oral administration of IPE for 2 weeks increased the differentiation of CD4+, CD8+, and CD19+ cells in splenocytes. These findings suggested that IPE has immunomodulatory effects and could be developed as an immunomodulatory supplement.


Subject(s)
Administration, Oral , Cell Proliferation , Cytokines , Ethanol , Gene Expression , Humans , Ice , In Vitro Techniques , Interleukin-6 , Jurkat Cells , Lymphocytes , Macrophages , Mesembryanthemum , Nitric Oxide
19.
Article in English | WPRIM | ID: wpr-16097

ABSTRACT

A survey was performed to investigate the infection status of zoonotic trematode (ZT) metacercariae in fish from a local market in Yangon City, Myanmar. A total of 264 fish (12 species) were collected through 4 times from December 2013 to June 2015. All collected fish were transferred to our laboratory on ice and examined by the artificial digestion method. More than 7 species of ZT metacercariae, i.e., Haplorchis taichui, H. pumilio, H. yokogawai, Centrocestus spp., Stellantchasmus falcatus, Pygidiopsis cambodiensis, and Procerovum sp. were detected. Metacercariae of H. taichui were collected in 58 (42.3%) out of 137 fish (5 species), and their average density was 42.9 per fish infected. Metacercariae of H. pumilio were detected in 96 (49.0%) out of 196 fish (9 species), and their average density was 23.6 per fish infected. H. yokogawai metacercariae were found in 40 (50.0%) out of 80 fish (5 species), and Centrocestus spp. metacercariae in 91 (50.8%) out of 179 fish (8 species), and their densities were 306 and 25.8 per fish infected, respectively. Metacercariae of S. falcatus and P. cambodiensis were detected only in mullets, Chelon macrolepis. A total of 280 Procerovum sp. metacercariae were found in 6 out of 12 climbing perch, Anabas testudineus. Morphological characteristics of adult flukes recovered from experimental animals were described. It has been first confirmed that fish from Yangon, Myanmar are commonly infected with various species of ZT metacercariae.


Subject(s)
Adult , Animals , Digestion , Humans , Ice , Metacercariae , Methods , Myanmar , Perches , Smegmamorpha , Trematoda
20.
Rev. bras. enferm ; 69(6): 1215-1222, nov.-dez. 2016. tab, graf
Article in Portuguese | LILACS, BDENF | ID: biblio-829861

ABSTRACT

RESUMO Objetivo: analisar as estratégias utilizadas para minorar a sede do paciente hospitalizado. Método: revisão integrativa, para a qual as bases de dados PubMed, LILACS, CINAHL e o conjunto de referências organizadas pelo Grupo de Estudo e Pesquisa da Sede foram selecionadas para a busca dos estudos primários, com os descritores: thirst, ice, cold, intervention, nursingcare, artificialsaliva. Resultados: a amostra da revisão foi composta de 10 estudos primários. As estratégias encontradas foram: baixa temperatura utilizando gaze congelada, lascas de gelo e água fria, mentol associado a estratégias frias, goma de mascar, acupressão, uso de canudo fino, substituto salivar e ingestão precoce de líquidos. Conclusão: a temperatura apresentou-se como estratégia predominante e efetiva para minorar a sede de pacientes cirúrgicos, em cuidado intensivo e em tratamentos de hemodiálise.


RESUMEN Objetivo: analizar las estrategias utilizadas para saciar la sed del paciente hospitalizado. Método: revisión integrativa, sobre estudios primarios seleccionados de las bases de datos PubMed, LILACS, CINAHL y del conjunto de referencias elaboradas por el Grupo de Estudio e Investigación de la Sed, con los descriptores: thirst, ice, cold, intervention, nursing care, artificial saliva. Resultados: la muestra de la revisión se compuso de 10 estudios primarios. Las estrategias halladas fueron: baja temperatura utilizando gasa congelada, hielo molido y agua fría, mentol asociado a estrategias frías, goma de mascar, acupresión, uso de sorbete delgado, sustituto salival e ingestión precoz de líquidos. Conclusión: la temperatura se presentó como estrategia predominante y efectiva para saciar la sed en pacientes quirúrgicos, en cuidados intensivos y en tratamientos de hemodiálisis.


ABSTRACT Objective: to analyze the strategies used to relieve the thirst of hospitalized patients. Method: an integrative review, for which the databases PubMed, LILACS, CINAHL and the group of references organized by the Group for Study and Research of Thirst were selected for the search of primary studies, with the keywords: thirst, ice, cold, intervention, nursing care, artificial saliva. Results: the review sample was composed of ten primary studies. The strategies found were: low temperature using frozen gauze, ice chips, and cold water, menthol associated with cold strategies, chewing gum, acupressure, and the use of a thin straw, substitute saliva, and early fluid ingestion. Conclusion: the temperature was presented as a predominant and effective strategy to relieve the thirst for surgical patients in intensive care and hemodialysis treatment.


Subject(s)
Humans , Critical Illness/therapy , Hospitalization , Thirst , Critical Illness/nursing , Ice , Saliva, Artificial/administration & dosage
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