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1.
Rev. colomb. cir ; 37(2): 298-304, 20220316. fig, tab
Article in Spanish | LILACS | ID: biblio-1362976

ABSTRACT

Las neoplasias apendiculares se presentan hasta en el 50 % de los casos como un episodio de apendicitis aguda. Existen características demográficas, clínicas y radiológicas que aumentan las posibilidades de un tumor apendicular subyacente, sin embargo, en la mayoría de los casos, son los hallazgos intraoperatorios los que alertan al cirujano. A pesar de que el tipo histológico determina la radicalidad del manejo quirúrgico de estos pacientes, algunas características macroscópicas pueden orientar a las patologías específicas y a una conducta adecuada. En general, los objetivos del manejo quirúrgico inicial se cumplen con una resección limitada al apéndice cecal, asociada a la citología de mucina y biopsia de los implantes peritoneales si están presentes, reservando las resecciones extendidas, como hemicolectomía derecha oncológica, para los pacientes con compromiso extenso de la base o del mesenterio apendicular ante la sospecha de neoplasias neuroendocrinas o adenocarcinoma del apéndice cecal.


Appendicular neoplasms present in up to 50% of cases as an episode of acute appendicitis. There are demographic, clinical and radiological characteristics that increase the chances of an underlying appendicular tumor; however, in most cases are the intraoperative findings that alert the surgeon. Although the histological type determines the radical nature of the surgical management of these patients, some macroscopic characteristics can guide specific pathologies and appropriate behavior. In general, the objectives of initial surgical management are met with a limited resection of the cecal appendix, associated with mucin cytology and biopsy of peritoneal implants if present, reserving extended resections such as oncological right hemicolectomy for patients with extensive compromise of the base or appendicular mesentery when neuroendocrine neoplasms or adenocarcinoma of the cecal appendix are suspected.


Subject(s)
Humans , Appendectomy , Appendiceal Neoplasms , Incidental Findings , Appendicitis , Adenocarcinoma, Mucinous
3.
Rev. colomb. cir ; 37(1): 129-134, 20211217. fig
Article in Spanish | LILACS | ID: biblio-1357598

ABSTRACT

La posibilidad de encontrar una neoplasia benigna o maligna del ovario, de forma inesperada durante una intervención quirúrgica abdominal, es una realidad para todos los especialistas en cirugía. Si bien en muchos casos se tratará de una lesión benigna, el riesgo de cáncer no debe subestimarse, ya que, por ejemplo, la ruptura intraoperatoria de una lesión quística maligna puede reestadificar a una paciente con cáncer de ovario del estadio IA al IC, con todas las consecuencias que esto implica, como la necesidad de requerir quimioterapia adyuvante y tener un peor pronóstico. Por otro lado, en mujeres premenopáusicas debe discutirse con la familia o la paciente (idealmente) el riesgo e implicaciones de la ooforectomía uni o bilateral, incluso si esto amerita dejar el quirófano para obtener el consentimiento, o posponer el procedimiento definitivo para un segundo tiempo. La consulta intraoperatoria a un ginecólogo, siempre que sea posible, se debe llevar a cabo con el fin de respaldar la conducta adoptada. Conocer el manejo adecuado de las masas anexiales encontradas de forma incidental durante una cirugía abdominal, es una prioridad para todos los cirujanos generales.


The possibility of finding a benign or malignant neoplasm of the ovary unexpectedly during abdominal surgery is a reality for all specialists in surgery. Although in many cases it will be a benign lesion, the risk of cancer should not be underestimated, since, for example, the intraoperative rupture of a malignant cystic lesion may well re-stage a patient with ovarian cancer from stage IA to IC, with the consequences that this implies, such as the need for adjuvant chemotherapy and a worse prognosis. On the other hand, in premenopausal women, the risk and implications of unilateral or bilateral oophorectomy should be discussed with the family or the patient (ideally), even if this implies leaving the operating room to obtain consent, or postponing the definitive procedure for a second time. Intraoperative consultation with a gynecologist, whenever possible, should be carried out in order to support the adopted behavior. Knowing the proper management of adnexal masses found incidentally during abdominal surgery is a priority for all general surgeons.


Subject(s)
Humans , Ovarian Cysts , Ovarian Neoplasms , Surgical Procedures, Operative , Krukenberg Tumor , Incidental Findings
4.
Rev. Assoc. Med. Bras. (1992) ; 67(9): 1328-1332, Sept. 2021. tab, graf
Article in English | LILACS | ID: biblio-1351488

ABSTRACT

SUMMARY OBJECTIVE: In coronary computed tomography angiography, a part of the lung parenchyma also enters the image area which is called the field of view. The aim of this study was to evaluate the rate of pulmonary abnormalities and document their association with demographic features in subjects undergoing multislice coronary computed tomography angiography obtained for the assessment of coronary artery disease. METHODS: This was a retrospective observational study evaluating the coronary computed tomography angiography scans of 1,050 patients (58.5% males and 47.3% smokers) with a mean age of 52.2±11.2 years, obtained between January 2018 and March 2020. Pulmonary abnormalities were reported as nodules, focal consolidations, ground-glass opacities, consolidations, emphysema, cysts, bronchiectasis, atelectasis, and miscellaneous. RESULTS: In total, 274 pulmonary abnormalities were detected in 266 patients (25.3%). The distribution of incidental lung findings was as follows: pulmonary nodules: 36.4%, emphysema: 15.6%, bronchiectasis: 11%, ground-glass opacities: 7.2%, atelectasis 7.2%, focal consolidations: 5%, cysts: 6%, consolidations: 2.5%, and miscellaneous: 9.1%. The patients with pulmonary pathology were older (55.5±11.4 versus 51.0±10.9 years), and the percentage of smokers was higher (60.1 versus 43.2%). The possibility of the presence of any incidental lung findings in field of view of coronary computed tomography angiography increases significantly over the age of 40.5 years (p<0.001, AUC 0.612, 95%CI 0.573-0.651). CONCLUSION: Multislice coronary computed tomography angiography can give important clues regarding pulmonary diseases. It is essential for the reporting radiologist to review the entire scan for pulmonary pathological findings especially in patients with smoking history and over the age of 40.5 years.


Subject(s)
Humans , Male , Female , Adult , Incidental Findings , Computed Tomography Angiography , Tomography, X-Ray Computed , Retrospective Studies , Coronary Angiography , Lung/diagnostic imaging , Middle Aged
5.
Infectio ; 25(2): 138-141, abr.-jun. 2021. graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1250081

ABSTRACT

Resumen Balantidium coli es el único miembro de la familia Balantidiidae capaz de producir infección en seres humanos. Presentamos un caso en un hombre de 43 años que ingresa para corrección quirúrgica de hernia ventral durante la cual se realizó apendicetomía profiláctica. En el estudio histopatológico se observó apéndice cecal con arquitectura conservada, sin la presencia de apendicitis ni periapendicitis. En la luz se reconocieron estructuras grandes (aproximado de 50 μm) redondas con citoplasma amplio con vacuolas grandes, cilias periféricas y núcleos densos, los cuales correspondieron a trofozoitos de Balantidium coli.


Abstract Balantidium coli is the only member of the Balantidiiae family capable of infecting human beings. We present one in a 43 years-old male admitted for a surgical co rrection of an incisional hernia with prophylactic appendicectomy. Histopathological findings reported the cecal appendix within normal architecture, appendicitis and peri-appendicitis free. At the lumen big, rounded shape structures (aprox. 50 mm) were visible with broad cytoplasm, big vacuoles, peripheral cilia and dense nucleus, corresponding to Balantidium coli trophozoites.


Subject(s)
Humans , Male , Adult , Appendix , Balantidium , Incidental Findings , Appendicitis , Coliforms , Infections
6.
Rev. colomb. gastroenterol ; 36(1): 126-129, ene.-mar. 2021. tab, graf
Article in Spanish | LILACS | ID: biblio-1251533

ABSTRACT

Resumen La mucosectomía endoscópica ha probado ser una alternativa efectiva para el tratamiento del cáncer gástrico temprano; sin embargo, se requiere de un seguimiento estricto para asegurar una conducta de manejo adecuada en caso de recurrencia. Se presenta el caso de un paciente de 54 años, con hallazgo incidental de un carcinoma gástrico temprano, a quien se le realizó mucosectomía endoscópica, con un reporte final de histopatología compatible con adenocarcinoma gástrico temprano y márgenes de resección negativos, con un seguimiento endoscópico e histopatológico a 2 meses negativos para malignidad.


Abstract Endoscopic mucosal resection has proven to be an effective alternative for the treatment of early gastric cancer. However, strict follow-up is necessary to ensure adequate management in the event of recurrence. This is the case of a 54-year-old patient with an incidental finding of early gastric carcinoma. He underwent endoscopic mucosal resection, with a final histopathology report compatible with early gastric adenocarcinoma and negative resection margins. Endoscopic and histopathological follow-up at 2 months showed negative results for malignancy.


Subject(s)
Humans , Male , Middle Aged , Stomach Neoplasms , Endoscopic Mucosal Resection , Recurrence , Incidental Findings , Research Report
9.
J. appl. oral sci ; 29: e20200978, 2021. tab, graf
Article in English | LILACS | ID: biblio-1286913

ABSTRACT

Abstract Mucopolysaccharidosis (MPS) is a group of rare and inherited metabolic disorders caused by the accumulation of macromolecule glycosaminoglycans inside lysosomes. Affected individuals may have dental and craniofacial tissue alterations, facilitating the development of several oral diseases. Objectives To assess, with panoramic radiographic images, the frequency of dental and maxillomandibular incidental findings among MPS individuals and compare them with non-MPS individuals. Methodology A cross-sectional study evaluating a sample of 14 MPS individuals and 28 non-MPS individuals aged from 5 to 26 years was carried out. They were matched for sex and age on a 2:1 proportion. Panoramic radiographs were assessed for the presence/absence of the following dental and maxillomandibular alterations: dental anomalies of number (hypodontia/dental agenesis, supernumerary teeth); anomalies of form (microdontia, macrodontia, conoid teeth, taurodontism, and root dilaceration); anomalies of position (impacted tooth, inverted tooth, tooth migration, partially bony teeth, complete bony teeth); periapical alterations (furcation lesion, circumscribed bone rarefaction); other alterations (radiolucent bone lesions, radiopaque bone lesions, radiopacity in the maxillary sinus, condylar hypoplasia). Differences between groups were tested by the Fisher's exact test and chi-square test (p<0.05). Results For intrarater agreement, Kappa values were 0.76 to 0.85. The presence of supernumerary teeth (p=0.003); conoid teeth (p=0.009); taurodontism (p<0.001); impacted teeth (p<0.001); partial bony teeth (p=0.040); complete bony teeth (p=0.013); and root dilaceration (p=0.047) were statistically more frequent in MPS individuals compared to non-MPS individuals. Bone rarefaction/furcation lesions (p=0.032), condylar hypoplasia (p<0.001), radiolucent bone lesions (p=0.001), and dentigerous cysts (p=0.002) were also more frequent in MPS individuals. Conclusion The presence of specific oral manifestations is more common in MPS individuals than non-MPS individuals.


Subject(s)
Humans , Child, Preschool , Child , Adolescent , Adult , Young Adult , Tooth Abnormalities/diagnostic imaging , Tooth, Supernumerary , Mucopolysaccharidoses/diagnostic imaging , Radiography, Panoramic , Cross-Sectional Studies , Incidental Findings
10.
Rev. cir. (Impr.) ; 72(3): 262-266, jun. 2020. ilus
Article in Spanish | LILACS | ID: biblio-1115553

ABSTRACT

Resumen El cáncer de vesícula es infrecuente a nivel mundial, a diferencia de su alta incidencia en Chile. Su pronóstico es malo en general, y dependerá de su forma de presentación, siendo mejor en los casos diagnosticados después de una colecistectomía laparoscópica por patología benigna. La reintervención, que incluye la resección hepática y linfadenectomía, es el pilar de la terapia curativa en esta neoplasia. Presentamos la descripción de la técnica quirúrgica realizada en los pacientes con cáncer de vesícula de diagnóstico incidental, en el Servicio de Cirugía de Clínica Alemana de Santiago y en el Hospital de la Fuerza Aérea de Chile. El abordaje laparoscópico representa una alternativa quirúrgica válida en el tratamiento de pacientes con cáncer de vesícula biliar diagnosticados después de la colecistectomía. La estandarización de la técnica debiera contribuir a su mayor empleo y a la obtención de buenos resultados desde un punto de vista oncológico.


Gallbladder cancer is considered an infrequent disease but in Chile has a higher incidence. Prognostic is considered dismal except in those patients in whom the diagnosis is performed after the cholecystectomy specimen study. Reoperation with gallbladder bed resection and lymphadenectomy is considered the treatment in patients with incidental cases. We show the way this operation is performed in Clinica Alemana of Santiago and in the Air Force Hospital. The laparoscopic approach is an alternative to those patients in whom the diagnosis was done after the cholecystectomy. Laparoscopy allows to accomplish same objectives and to obtain identical results that the open approach. The technical standardization should contribute to spread its employment and to improve the results.


Subject(s)
Humans , Biliary Tract Surgical Procedures/methods , Gallbladder/surgery , Gallbladder Neoplasms/surgery , Lymph Node Excision/methods , Biliary Tract Surgical Procedures/adverse effects , Laparoscopy , Disease Management , Incidental Findings , Lymph Node Excision/standards
11.
Int. j. odontostomatol. (Print) ; 14(2): 150-153, June 2020. graf
Article in Spanish | LILACS | ID: biblio-1090667

ABSTRACT

El seno maxilar (SM) es una cavidad par presente en el hueso maxilar, que puede presentar diversas alteraciones o lesiones patológicas factibles de ser pesquisadas mediante estudios imagenológicos. En este sentido, la opacidad, el ocupamiento y/o engrosamiento de las mucosas son los signos orientadores para el diagnóstico de patologías en estas estructuras, las que pueden ir desde sinusitis, hasta antrolitos, pasando por hipoplasias, pseudoquistes u osteomas. En el siguiente reporte presentamos el caso de una mujer de 75 años de edad en la cual mediante examinación radiográfica de rutina se observa un cuerpo extraño en el SM derecho en relación a diente 1.6. De acuerdo a esto, se solicitó una tomografía computarizada cone-beam (CBCT) para evaluar posibles implicancias con tratamiento dental rehabilitador. Al examen se observan dos estructuras de alta densidad (densidad metálica), redondeadas, una al lado de la otra, en contacto inmediato a la cortical sinusal sin comprometerla. También se observa una cortical sinusal conservada en todo su recorrido y discreto engrosamiento mucoso en relación a dichas estructuras. En consideración con los antecedentes de la paciente, se opta por un manejo conservador del hallazgo mediante controles periódicos. Se propone la hipótesis de la formación de un antrolito de origen exógeno, que se corresponde con el historial de tratamiento endodóntico en la zona. El diagnóstico diferencial de los hallazgos radiográficos encontrados es fundamental para establecer los lineamientos terapéuticos de nuestros pacientes, por ello es importante contar con personal clínico capacitado para la interpretación de las imágenes.


The maxillary sinus (SM) is an even cavity present in the maxillary bone, which may present a number of pathological alterations or lesions that can be investigated through imaging analysis. In this sense, opacity, location and / or thickening of the mucous membranes are guides for the diagnosis of pathologies in these structures. These can range from sinusitis, to antrolites, to hypoplasias, pseudocysts or osteomas. In this study the case of a 75-year-old woman is presented. During routine radiographic examination, a foreign body was observed in the right MS in relation to tooth 1.6. A cone-beam computed tomography (CBCT) was requested to evaluate possible rehabilitative dental treatment. Upon examination, two highdensity rounded structures (metal density) adjacent to each other were noted. The structures were in direct contact with the sinus cortex without compromising it. Furthermore in relation to the above structures, scant cortical sinus was observed throughout its course, as well as slight mucous thickening. Considering the patient's background, it was determined to use conservative treatment through periodic controls. Hypothesis of an exogenous mass is proposed, corresponding to the history of endodontic treatment in the area. In view of the differential diagnosis of radiographic findings found, it is essential to implement therapeutic guidelines for patients and have trained clinical staff available to interpret the images.


Subject(s)
Humans , Female , Aged , Foreign Bodies/diagnostic imaging , Maxillary Sinus/diagnostic imaging , Radiography, Panoramic , Incidental Findings , Cone-Beam Computed Tomography , Conservative Treatment
12.
Int. j. odontostomatol. (Print) ; 14(2): 213-219, June 2020. tab, graf
Article in English | LILACS | ID: biblio-1090677

ABSTRACT

Facial pain is one of the symptoms of temporomandibular disorders (TMDs) but can be associated with other pathological conditions. The present study retrospectively evaluated the occurrence of nonarticular incidental findings in panoramic radiographs in a group of patients with painful TMDs. Outpatients with a diagnosis of TMD were included and distributed into three groups: arthralgia, myalgia or arthralgia and myalgia, according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Nonarticular incidental findings of their panoramic radiographs were classified in relation to pathological, dental and endodontic status. The dependency relationships among the variables were analyzed using the likelihood test. Sixty patients (38 women and 22 men; mean age: 36.9 years) were evaluated. There was a predominance of arthralgia plus disc displacement (43.4 %), followed by myopain plus arthralgia and disc displacement (38.3 %) and myopain (18.3 %). Pathologic radiographic changes such as bone loss, caries, maxillary sinus opacification and periapical lesions were frequent. Dental alterations such as the absence and altered position of teeth and impacted teeth were frequent. Endodontic changes such as periapical lesions with or without endodontic treatment were frequent. There was no significant difference between groups except for gyroversion. The incidental findings were compatible with caries, sinusitis, impacted tooth and periapical lesion, which may be associated with orofacial pain and could potentially be superimposed on the initial diagnosis, although this hypothesis was discarded. Findings such as the absence and altered position of teeth were also frequent, which may represent occlusal factors associated with TMDs.


El dolor orofacial es uno de los síntomas de los trastornos temporomandibulares (TTM), pero puede estar asociado con otras afecciones patológicas. El presente estudio evaluó retrospectivamente la aparición de hallazgos incidentales no articulares a través de ortopantomografías en un grupo de pacientes con TTM dolorosas. Se incluyeron pacientes con diagnóstico de TTM y se distribuyeron en tres grupos: artralgia, mialgia o artralgia y mialgia, de acuerdo con los criterios de diagnóstico para los trastornos temporomandibulares (DC/TMD). Los hallazgos incidentales no articulares de las ortopantomografias se clasificaron en relación al estado patológico, dental y endodóncico. Las relaciones de dependencia entre las variables se analizaron mediante la prueba de probabilidad. Fueron evaluados 60 pacientes (38 mujeres y 22 hombres; edad media: 36,9 años). Hubo predominio de artralgia más desplazamiento de disco (43,4 %), seguido de mialgia más artralgia y desplazamiento de disco (38,3 %) y mialgia (18,3 %). Las alteraciones radiográficas patológicas como pérdida ósea, carie dentaria, opacificación del seno maxilar y lesiones periapicales fueron frecuentes. Entre las alteraciones dentales, las impactaciones, malposiciones o ausencias dentarias fueron frecuentes. Entre las alteraciones endodóncicas, las lesiones periapicales frecuentes. No hubo diferencias significativas entre los grupos, excepto para la girosversión dentaria. Los hallazgos incidentales fueron compatibles con carie dentaria, sinusitis, diente impactado y lesión periapical, lo que podría estar asociado con el dolor orofacial y así estar sobrepuesto en el diagnóstico inicial, aunque esta hipótesis fue descartada. Hallazgos como la ausencia y la posición alterada de los dientes también fueron frecuentes, lo que puede representar factores oclusales asociados con TTM.


Subject(s)
Humans , Male , Female , Adult , Facial Pain/diagnostic imaging , Radiography, Panoramic , Mandibular Diseases/diagnostic imaging , Facial Pain/etiology , Mandibular Diseases/complications , Mandibular Diseases/epidemiology , Temporomandibular Joint Disorders/diagnostic imaging , Retrospective Studies , Incidental Findings
13.
Rev. Ateneo Argent. Odontol ; 62(1): 25-30, jun. 2020. ilus
Article in Spanish | LILACS | ID: biblio-1148131

ABSTRACT

El creciente número de técnicas radiográficas realizadas por paciente para diagnóstico y planificación provoca un aumento en el número de hallazgos incidentales. La descripción de un hallazgo incidental puede desencadenar atención médica adicional, que incluye otros procedimientos y tratamientos de diagnóstico, con lo cual, en muchas ocasiones es necesario derivar al paciente para tratar la patología descubierta en forma incidental. La CBCT puede ayudar a detectar la presencia de lesión periapical no diagnosticada previamente, donde la evaluación clínica previa y las radiografías convencionales no han revelado la patología. La patología asintomática u oculta puede conducir a un diagnóstico tardío, lo que puede afectar negativamente las posibles estrategias de tratamiento y los resultados. La detección temprana y la precisión diagnóstica son esenciales. La CBCT es una técnica que proporciona vistas de zonas anatómicas con las cuales la mayoría de los odontólogos no están familiarizados y que pueden revelar patología oculta, permitiendo diagnósticos más precisos y confiables, y reduciendo así la posibilidad de perder la patología clínicamente relevante. Este articulo trata de sintetizar las ventajas del uso de la tomografía para diagnosticar el hallazgo incidental (AU)


The increasing number of radiographic techniques performed by the patient for diagnosis and planning causes an increase the number of incidental findings. The description of an unexpected finding can trigger additional medical care including, other diagnostic procedures and treatments, therefore, in many occasions it is necessary to refer the patient to treat the pathology discovered incidentally. CBCT may aid in detecting the presence of previously undiagnosed periapical disease, where prior clinical evaluation and conventional radiographs have failed to reveal pathology. Asymptomatic or occult pathology may lead to delayed diagnosis, which may adversely affect eventual treatment strategies and outcomes. Early detection and improved diagnostic accuracy are essential, also, provide views of anatomy that most dentists have never before seen; in addition, they may reveal occult pathology, enabling more accurate and reliable diagnoses thereby reducing the possibility of missing clinically relevant disease (AU)


Subject(s)
Humans , Incidental Findings , Cone-Beam Computed Tomography , Periapical Diseases/diagnostic imaging , Radiography, Dental/methods , Radiography, Panoramic
14.
Autops. Case Rep ; 10(1): 2019133, Jan.-Mar. 2020. ilus
Article in English | LILACS | ID: biblio-1052963

ABSTRACT

Pulmonary alveolar microlithiasis (PAM) is a rare entity, presenting mostly as an incidental finding. This disease has an autosomal recessive inheritance with inactivating mutations in the gene "solute carrier family 34 member 2". The present study was conducted to bring attention to this rare though preventable disease. The study was a cross-sectional descriptive study, conducted at the Department of Pathology, of a tertiary care hospital in New Dehli-India. PAMs were incidentally seen in two patients diagnosed with micronodular hepatic cirrhosis leading to reanalysis of 212 autopsies, retrospectively. Statistical analysis was done using Stata 14.0. We observed three forms (Type A, B and C) of round hyaline bodies measuring in diameter with thin delicate, radiating fibrils. These bodies were PAS positive, showed black discolouration of the pigment with von Kossa stain and birefringence on polarized microscopy using Congo red stain, however the refringence was light green as compared to apple green birefringence seen with amyloid deposition. PAM has a slow progressive course leading to a high rate of incidental detection. Drugs known to inhibit the micro-crystal growth of hydroxyapatite may slow the disease progression. The family members of patients with PAM may also be kept on follow up with regular imaging. Key messages: It is important to bring out the incidental finding as, seemingly innocuous observations may provide valuable insight into incurable diseases, especially rare diseases.


Subject(s)
Humans , Male , Adult , Middle Aged , Incidental Findings , Lung Diseases/pathology , Autopsy , Calcification, Physiologic , Rare Diseases
15.
Rev. cir. (Impr.) ; 72(1): 72-75, feb. 2020. ilus
Article in Spanish | LILACS | ID: biblio-1092894

ABSTRACT

Resumen Introducción Los leiomiosarcomas de la vena cava inferior son tumores raros, sólo hay 300 casos descritos en la literatura. Su incidencia es mayor en mujeres, suelen aparecer entre los 50-60 años, y presentan una progresión lenta y mal pronóstico. Los síntomas son inespecíficos haciendo que el diagnóstico se realice de forma tardía, éste se realiza mediante pruebas de imagen y biopsia guiada. Caso clínico Se presenta el caso de un varón de 73 años con diagnóstico de leiomiosarcoma de la vena cava inferior, como hallazgo incidental en TC de control, tratado mediante radioterapia neoadyuvante, cirugía y radioterapia intraoperatoria. Discusión El único tratamiento que ha descrito modificaciones en la supervivencia es la cirugía. El papel de la adyuvancia y neoadyuvancia en estos tumores es muy controvertido. La elección de la actitud terapéutica dependerá de la localización del tumor, tamaño, la relación con estructuras adyacentes y la presencia de circulación colateral.


Introduction Leiomyosarcomas of the inferior vena cava are rare tumors, with fewer than 300 cases reported. Its incidence is higher in females, usually appear in the sixth decade and they have a slow-growing and poor prognosis. Symptoms are generally non-specific. Diagnosis is made with imaging studies and guided biopsy. Clinical Case We report a case of a 73-year-old male patient with leimyosarcoma of the inferior vena cava treated by neoadjuvant radiotherapy, surgery and intraoperative radiotherapy. Discussion Surgery is the only treatment that can improve the survival. The role of the adjuvancy and neoadjuvancy is very controversial. Surgical management is determined by the location of the tumour, the relationship with adjacent structures and the presence of collateral veins.


Subject(s)
Humans , Male , Aged , Vena Cava, Inferior/pathology , Vascular Neoplasms/surgery , Vascular Neoplasms/diagnostic imaging , Leiomyosarcoma/surgery , Leiomyosarcoma/diagnostic imaging , Patient Care Team , Postoperative Period , Vena Cava, Inferior/surgery , Tomography, X-Ray Computed , Treatment Outcome , Radiotherapy, Adjuvant/methods , Incidental Findings , Leiomyosarcoma/radiotherapy
16.
Rev. méd. Chile ; 148(1): 10-16, Jan. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1094201

ABSTRACT

Background: Thyroid incidentalomas detected by 18F-Fludeoxyglucose (FDG) PET/CT are defined as an incidental and unexpected thyroid focus present in a patient studied for a non-thyroid disease. Aim: To assess the frequency of malignancy of nodular thyroid incidentalomas, and their association with 18F-FDG avidity (standard uptake value (SUV) max). Material and Methods: Whole body PET/CT performed from December 2008 to December 2017 were reviewed selecting those that showed nodular thyroid foci. Glands with diffuse increased uptake were excluded. Thyroid ultrasonography and fine-needle aspiration cytology (FNAC) performed after PET/CT were reviewed. Bethesda score and SUVmax were correlated. Results: Of 5,100 whole body 18F-FDG PET/CT, 119 showed a thyroid nodular uptake (2.3%). Forty eight percent of these patients were studied with FNAC or surgery, 50% of which (29/58) were confirmed as malignant. Benign nodules showed significantly lower 18F-FDG uptake (n = 20, SUVmax: 3.5 ± 1.7) than Bethesda V-VI (n=24, SUVmax: 8.2 ± 5.2) and thyroid metastases (n=5, SUVmax: 6.3 ± 2.1). The best cut-off value to distinguish between benign and malignant nodules was a SUVmax of 5.0, with a sensitivity of 76% (95% confidence intervals (CI) 56-90%), a specificity of 85% (95% CI 62 - 97%), and positive likelihood ratio of 5 (95% CI 1.8 - 14.6). The size of the thyroid nodule was not predictive of malignancy. Conclusions: Half of nodular thyroid incidentalomas detected by 18F-FDG PETC/CT are malignant. A nodule with a SUVmax ≥ 5,0 is highly suggestive of malignancy, regardless of its size.


Subject(s)
Humans , Thyroid Neoplasms/diagnostic imaging , Thyroid Nodule , Retrospective Studies , Radiopharmaceuticals , Fluorodeoxyglucose F18 , Incidental Findings , Positron Emission Tomography Computed Tomography
18.
ABCD arq. bras. cir. dig ; 33(1): e1496, 2020.
Article in English | LILACS | ID: biblio-1130518

ABSTRACT

ABSTRACT Background: Incidental gallbladder cancer is defined as a cancer discovered by histological examination after cholecystectomy. It is a potentially curable disease. However, some questions related to their management remain controversial and a defined strategy is associated with better prognosis. Aim: To develop the first evidence-based consensus for management of patients with incidental gallbladder cancer in Brazil. Methods: Sixteen questions were selected, and 36 Brazilian and International members were included to the answer them. The statements were based on current evident literature. The final report was sent to the members of the panel for agreement assessment. Results: Intraoperative evaluation of the specimen, use of retrieval bags and routine histopathology is recommended. Complete preoperative evaluation is necessary and the reoperation should be performed once final staging is available. Evaluation of the cystic duct margin and routine 16b1 lymph node biopsy is recommended. Chemotherapy should be considered and chemoradiation therapy if microscopically positive surgical margins. Port site should be resected exceptionally. Staging laparoscopy before reoperation is recommended, but minimally invasive radical approach only in specialized minimally invasive hepatopancreatobiliary centers. The extent of liver resection is acceptable if R0 resection is achieved. Standard lymph node dissection is required for T2 tumors and above, but common bile duct resection is not recommended routinely. Conclusions: It was possible to prepare safe recommendations as guidance for incidental gallbladder carcinoma, addressing the most frequent topics of everyday work of digestive and general surgeons.


RESUMO Racional: Carcinoma incidental da vesícula biliar é definido como uma neoplasia descoberta por exame histológico após colecistectomia videolaparoscópica. É potencialmente uma doença curável. Entretanto algumas questões relacionadas ao seu manuseio permanecem controversas e uma estratégia definida está associada com melhor prognóstico. Objetivo: Desenvolver o primeiro consenso baseado em evidências para o manuseio de pacientes com carcinoma incidental da vesícula biliar no Brasil. Métodos: Dezesseis questões foram selecionadas e para responder as questões e 36 membros das sociedades brasileiras e internacionais foram incluídos. As recomendações foram baseadas em evidências da literatura atual. Um relatório final foi enviado para os membros do painel para avaliação de concordância. Resultados: Avaliação intraoperatória da peça cirúrgica, uso de bolsas para retirar a peça cirúrgica e exame histopatológico de rotina, foram recomendados. Avaliação pré-operatória completa é necessária e deve ser realizada assim que o estadiamento final esteja disponível. Avaliação da margem do ducto cístico e biópsia de rotina do linfonodo 16b1 são recomendadas. Quimioterapia deve ser considerada e quimioradioterapia indicada se a margem cirúrgica microscópica seja positiva. Os portais devem ser ressecados excepcionalmente. O estadiamento laparoscópico antes da operação é recomendado, mas o tratamento radical por abordagem minimamente invasiva deve ser realizado apenas em centros especializados em cirurgia hepatopancreatobiliar minimamente invasiva. A extensão da ressecção hepática é aceitável até que seja alcançada a ressecção R0. A linfadenectomia padrão é indicada para tumores iguais ou superiores a T2, mas a ressecção da via biliar não é recomendada de rotina. Conclusões: Recomendações seguras foram preparadas para carcinoma incidental da vesícula biliar, destacando os mais frequentes tópicos do trabalho diário do cirurgião do aparelho digestivo e hepatopancreatobiliar.


Subject(s)
Humans , Female , Gallbladder Neoplasms , Brazil , Carcinoma , Retrospective Studies , Incidental Findings , Consensus , Positron Emission Tomography Computed Tomography , Lymph Node Excision , Neoplasm Staging
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