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1.
J. Hum. Growth Dev. (Impr.) ; 30(2): 301-310, May-Aug. 2020. ilus, tab
Article in English | LILACS (Americas), INDEXPSI | ID: biblio-1114939

ABSTRACT

INTRODUCTION: Elective cesarean section is associated with several damages to the newborn's health, such as respiratory, gastrointestinal problems and diabetes that last throughout life. However, few studies discuss aspects related to psychological developmentOBJECTIVE: To investigate the development of Brazilian children according to the type of birth and gestational age in the cognitive, language, motor, socio-emotional and adaptive behavior domainsMETHODS: This is an exploratory and descriptive cross-sectional study conducted in the city of São Bernardo do Campo, São Paulo, Brazil, between June 2016 and March 2017. The final sample consisted of 263 children up to 42 months of age. For data collection were applied a socio demographic questionnaire and the Bayley-III Scale. The statistical analysis was based on both a North American reference sample and a local sample using the SPSS version 21, through Pearson's Chi-square statistical test and significance criteria p <0.05RESULTS: A significant difference (p<0.005) was observed, with a higher risk of problems in fine motor development and expressive language in children born at pre-term between 37- 39 weeks compared to those born at term between 39 - 41 weeks. Significant difference (p<0.005) was also observed in sensory processing and adaptive behavior, with greater impairment in children born via elective cesarean section compared to those born vaginallyCONCLUSION: Despite its limitations and discrepancies, this research indicates potential impairments in the psychological development of children born at early term via elective cesarean


INTRODUÇÃO: A cesárea eletiva está associada a diversos prejuízos à saúde do recém-nascido, como problemas respiratórios, gastrointestinais e diabetes, que perduram ao longo da vida. No entanto, poucos estudos discutem os aspectos relacionados ao desenvolvimento psicológicoOBJETIVO: Investigar o desenvolvimento de crianças brasileiras segundo a via de parto e a idade gestacional nos domínios cognitivo, linguagem, motor, socioemocional e comportamento adaptativoMÉTODO: Trata-se de um estudo exploratório-descritivo, transversal, realizado no município de São Bernardo do Campo, entre junho de 2016 e março de 2017. A população foi composta por 400 crianças até 42 meses de idade. Para coleta de dados foram aplicados questionário sociodemográfico e Escala Bayley-III. Foi utilizada para análise estatística tanto a normatização oferecida pela Escala Bayley (norte-americana) quanto a normatização referente à amostra estudada, por meio do SPSS version 21, utilizando o teste estatístico do Qui-Quadrado de Pearson, critérios de significância p<0,05RESULTADOS: Observou-se diferença significativa (p<0,005), com maior risco de problemas no desenvolvimento motor fino e na linguagem expressiva em crianças nascidas a termo precoce (37 a<39 semanas) quando comparadas às nascidas a termo (=39 a <41 semanas). Diferença significativa (p<0,005) também foi observada no processamento sensorial e comportamento adaptativo, com maior prejuízo observado nas crianças nascidas via CE em comparação às nascidas de parto vaginalCONCLUSÃO: Este estudo evidencia o aumento de riscos psicológicos em crianças nascidas via cesárea eletiva quando comparadas com as nascidas por parto vaginal nos aspectos relacionados ao processamento sensorial, motricidade fina, linguagem expressiva e emissão de comportamentos adaptativos


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Infant, Premature , Cesarean Section , Child Development , Child Health Services , Natural Childbirth
2.
Revista Digital de Postgrado ; 9(2): 216, ago. 2020.
Article in Spanish | LILACS (Americas), LIVECS | ID: biblio-1103452

ABSTRACT

Los primeros mil días de vida, desde la concepción hasta el final de los primeros dos años de vida, constituye un período crucial para establecer el desarrollo de la enfermedad o de la salud en la vida futura de los individuos. La exposición a ambientes adversos determinará las alteraciones temporales en el ADN que perduran en el tiempo que dicha exposición exista. Las políticas y programas destinados a garantizar el bienestar durante esta ventana crítica del crecimiento son cruciales para que la población goce de las mejores condiciones posibles que permitan la expresión de su máximo potencial, al cual están programados para desarrollar. Palabras clave: condiciones ambientales, programas y políticas(AU)


The first thousand days of life, from the conception until the end of the first two years of life, constitutes a key period in which the development of disease or health establishes in the future lives of individuals. Exposure to adverse environments will determine the temporary impairments in DNA that last as long as the exposure exists. Policies and programs aimed at guaranteeing well-being during this critical window of growth are crucial for the population to enjoy the best possible conditions that allow the expression of their maximum potential, to which they are programmed to develop(AU)


Subject(s)
Humans , Infant, Newborn , Infant , Social Conditions , Nutrition Programs , Infant Nutrition Disorders , Growth and Development , Poverty , Malnutrition , Prenatal Nutrition
3.
Odontoestomatol ; 22(35): 62-71, jul. 2020.
Article in Spanish | LILACS (Americas), InstitutionalDB | ID: biblio-1103066

ABSTRACT

Introducción: La boca del recién nacido se contamina inmediatamente con microorganismos maternos. Caufield determinó la colonización con SGM para niños americanos a los 26 meses de edad. Estudios latinoamericanos la ubican entre los 14,9-18 meses. Objetivos: Identificar el momento de adquisición y colonización del SGM en una población de niños uruguayos y relacionarlo con factores del niño y maternos. Establecer el tiempo necesario para la recolección de la muestra y estudio de su pérdida. Método: Estudio observacional, longitudinal prospectivo, de 83 pares madre-hijo de un policlínico de Montevideo. De 83 pares examinados, 20 completaron el estudio. Se incluyeron niños de 0-9 meses, con/sin dientes y primera toma salival negativa para SGM. Resultados: Edad promedio de adquisición del SGM 16,4 meses (±4,13) y colonización 18,6 meses (±3,80) de edad. La pérdida de la muestra fue 71,42%. Conclusiones: La colonización resultó similar a la encontrada por Florio (Brasil), observándose diferencias significativas con Caufield (EEUU).


Introduction: The newborn's mouth is immediately contaminated with maternal microorganisms during birth. Caufield determined that the average age of colonization with Streptococcus Mutans (SM) for American children was 26 months old. Latin American studies indicate that it occurs at an age between 14.9 and 18 months old. Objectives: To identify the time of Sm acquisition and colonization in a population of Uruguayan children and to relate it with various child and mother factors. To establish the time needed to collect the sample and its loss. Methods: Observational, longitudinal prospective study, of 83 mother-child pairs from a medical center in Montevideo. From the 83 pairs examined, 20 completed the study. Children between 0-9 months old, with/without teeth, whose first salivary sample was negative for Sm, were included. Results: The mean age of Sm acquisition was 16.4 months (± 4.13), and colonization occurred at 18.6 months (± 3.80) of age. The sample loss was 71.42%. Conclusions: The colonization found was similar to that found by Florio (Brazil) but showed significant differences with Caufield's results (USA).


Introdução: A boca do recém-nascido é imediatamente contaminada por microrganismos maternos. Caufield determinou a colonização com SGM para crianças americanas aos 26 meses de idade. Estudos latino-americanos o situam entre 14,9-18 meses. Objetivos: Identificar o momento de aquisição e colonização do SGM em uma população de crianças uruguaias e relacioná-lo com fatores da criança e da mãe. Estabeleça o tempo necessário para coletar a amostra e estudar sua perda. Método: Estudo observacional, longitudinal prospectivo, de 83 pares mãe-filho da uma policlínica de Montevidéu. Dos 83 pares examinados, 20 completaram o estudo. Foram incluídas crianças de 0-9 meses com / sem dentes e primeira amostra salivar negativa para SGM. Resultados: Idade média de aquisição do SGM 16,4 meses (± 4,13) e colonização 18,6 meses (± 3,80) de idade. A perda estabelecida da amostra foi 71,42%. Conclusões: A colonização foi semelhante aos de Florio (Brasil), observando diferenças significativas com Caufield (EUA).


Subject(s)
Humans , Infant, Newborn , Infant , Child, Preschool , Streptococcus mutans , Uruguay , Infant
4.
ABCS health sci ; 45: [1-7], 02 jun 2020. tab
Article in English | LILACS (Americas) | ID: biblio-1097554

ABSTRACT

INTRODUCTION: The period between gestation and 24 months of age corresponds to the moment of opportunities for the development and growth of the child. OBJECTIVE: To analyze factors associated with breastfeeding in children aged 6 to 23 months. METHODS: Crosssectional study carried out during the National Polio Vaccination Campaign 2012 in Guarapuava, Paraná Brazil with children aged 6-23 months, comprising a sample of 1,750 individuals. For the identification of the factors associated with breastfeeding, Poisson regression models were applied, estimating Prevalence Ratios (PR) and 95% Confidence Intervals (95% CI). Bivariate models were developed covering each of the independent variables and the dependent variable. RESULTS: The independent factors associated with early breastfeeding interruption in 1,355 infants were: use of baby-bottle (PR 4.74, CI 3.45-6.52), use of pacifier (PR 1.47, CI 1.30-1.66), not being breastfed in the first hour of life (PR 1.14, CI 1.05-1.25) and mother working out of home (PR 1.12, CI 1.01-1.24). Maternal schooling lower than 8 years was a protective factor for the continuity of breastfeeding (PR 0.88, CI 0.80-0.96). CONCLUSIONS: The use of nipples, not being breastfed in the first hour of life and maternal work interfered in the continuity of breastfeeding. From this knowledge it is possible to propose recommendations for actions to promote breastfeeding at the local level.


INTRODUÇÃO: O período entre a gestação e os 24 meses de idade corresponde ao momento de oportunidades para o desenvolvimento e crescimento da criança. OBJETIVO: Analisar fatores associados ao aleitamento materno (AM) em crianças de 6 a 23 meses. MÉTODOS: Estudo transversal realizado na Campanha Nacional de Vacinação contra Poliomielite 2012 em Guarapuava-PR com crianças de 6-23 meses, totalizando uma amostra de 1.750 indivíduos. Para a identificação dos fatores associados ao AM foram construídos modelos de regressão de Poisson, obtendo-se Razões de Prevalências (RP) e Intervalos de Confiança (IC) de 95%. Modelos bivariados foram elaborados abrangendo cada uma das variáveis independentes e a variável dependente. RESULTADOS: Os fatores independentes associados à interrupção do AM em 1.355 crianças foram: fazer uso de mamadeira (RP 4,74; IC 3,45-6,52), usar chupeta (RP 1,47; IC 1,30-1,66), não ser amamentada na primeira hora de vida (RP 1,14; IC 1,05-1,25) e a mãe trabalhar fora (RP 1,12; IC 1,01-1,24). A escolaridade materna inferior a oito anos foi um fator de proteção para a continuidade do AM (RP 0,88; IC 0,80-0,96). CONCLUSÃO: O uso de bicos, não ser amamentado na primeira hora de vida e o trabalho materno interferiram na continuidade do AM, a partir desse conhecimento é possível propor recomendações de ações de promoção do AM em nível local.


Subject(s)
Humans , Breast Feeding , Infant , Sociological Factors
5.
ABCS health sci ; 45: [1-4], 02 jun 2020. tab, graf
Article in English | LILACS (Americas) | ID: biblio-1097543

ABSTRACT

INTRODUCTION: For post-surgical rehabilitation of the anterior cruciate ligament, the medialis and the lateralis vastus need to be worked on for good recovery. There is the discussion about the isometric and isotonic exercises to be used in the rehabilitation phase, and their results diverge in the literature. OBJECTIVE: This study aims to compare the activation of the medialis and the lateralis vastus in isometric and isotonic exercises. METHODS: Eleven subjects (seven men and four women) physically active and experienced in resistance training participated in the study. Anamnesis, anthropometric assessment, 10 Repetition maximum (RM) load test, maximum voluntary isometric contraction test and squat test were performed. RESULTS: For the vastus lateralis of the right leg, the electromyographic activity was significantly higher in the maximal isometric voluntary contraction compared to the dynamic squatting (p<0.05). The same was observed for the left leg (p<0.05). CONCLUSION: Recruitment of the medial and the lateral vastus in isometric exercises is higher in relation to isotonic exercises.


INTRODUÇÃO: Para a reabilitação pós-cirúrgica do ligamento cruzado anterior, os vastos medial e lateral precisam ser trabalhados visando uma boa recuperação. Discute-se a respeito dos exercícios isométricos e isotônicos a serem utilizados na fase de reabilitação, tendo seus resultados divergentes na literatura. OBJETIVO: Assim, o objetivo do presente estudo é comparar a ativação dos vastos medial e lateral em exercícios isométricos e isotônicos. MÉTODOS: Participaram deste estudo 11 sujeitos (sete homens e quatro mulheres), fisicamente ativos e com experiência em musculação. Foi realizada a anamnese, a avaliação antropométrica, o teste de carga de 10 repetições máximas (RM), o teste de contração voluntária isométrica máxima e o teste de agachamento. RESULTADOS: No vasto lateral da coxa direita, a atividade eletromiográfica foi significativamente maior na contração voluntária isométrica máxima em relação ao agachamento dinâmico (p<0,05). O mesmo foi observado na coxa esquerda (p<0,05). CONCLUSÃO: O recrutamento dos vastos medial e lateral em exercícios isométricos é maior em relação a exercícios isotônicos.


Subject(s)
Humans , Male , Female , Infant , Quadriceps Muscle , Anterior Cruciate Ligament Injuries/rehabilitation , Isometric Contraction , Isotonic Contraction , Electromyography
6.
Int. j. morphol ; 38(3): 596-601, June 2020. tab, graf
Article in Spanish | LILACS (Americas) | ID: biblio-1098293

ABSTRACT

Las valvas cardíacas y especialmente la valva atrioventricular izquierda (VAVI) ha sido considerada por largo tiempo, como una estructura pasiva. Sin embargo, han surgido nuevas teorías que reconocen a esta estructura como una "valva viva", con un funcionamiento de mayor autonomía y dinámico. En esta línea, existen estudios en donde se ha concluido que la ausencia de tejidos contráctiles en una valva, generan ondulaciones no fisiológicas. Por el contrario, se ha señalado la presencia de tejido contráctil en la valva, lo que refleja una activación ondulante. Basado en lo anterior, el objetivo del presente estudio fue determinar la presencia de fibras musculares cardíacas en las cúspides de la VAVI. Se utilizaron 12 cúspides, 6 anteriores y 6 posteriores, de 7 cadáveres adultos (4) y lactantes (3) de distintas edades, sin patologías cardíacas. Las muestras pertenecían a la Facultad de Medicina de la Universidad Estadual de Ciencias da Saúde de Alagoas, Maceió, Brasil. Estas muestras fueron tratadas con procesamiento histológico de rutina. Los hallazgos morfológicos a un aumento de 4x mostraron células musculares que fueron visibles principalmente por el lado atrial en la totalidad de las cúspides, tanto inmersas en el tejido conectivo denso del anillo fibroso como en el tejido conectivo laxo. Al verificar la naturaleza de las fibras con un aumento mayor (100x), se detectaron estrías transversales en todas las muestras estudiadas, lo cual afirma la presencia de fibras musculares estríadas cardíacas en la VAVI. Los resultados obtenidos aportan al conocimiento de la microestructura y tejido contráctil de las cúspides de la VAVI. Por lo tanto, resulta de gran relevancia seguir profundizando en los conocimientos morfológicos de la VAVI, para sentar una base sólida sobre la microestructura contráctil en los diferentes estadíos del ser humano.


Cardiac valves and particularly, the left atrioventricular valve (LAVV) have long been considered passive structures. Nonetheless, there are more recent hypothesis that recognize this structure as a "living valve", with greater autonomy and dynamic function. Along these lines, some studies have concluded that the absence of contractile tissues in a valve, generates non-physiological undulations. In contrast, the presence of contractile tissue in the valve has been reported, reflecting a waving activation. Based on the above, the objective of the present study was to determine the presence of cardiac muscle fibers in the cusps of the LAVV. 12 cusps, 6 anterior and 6 posterior. Therefore, 7 adult (4) and lactating (3) bodies of different ages without cardiac pathologies were used. The samples belonged to the Faculty of Medicine of the Universidade de Ciencias da Saude de Alagos, Maceió, Brazil. The samples were treated with routine histological processing. Morphological findings at an increase of 4x showed muscle cells that were visible mainly from the atrial side in all the cusps, both immersed in the dense connective tissue of the fibrous ring and in loose connective tissue. Transverse striations were detected in all samples studied, when verifying the nature of the fibers with greater increase (100x), confirming the presence of cardiac striated muscle fibers in the LAVV. The results obtained contribute to the knowledge of the microstructure and contractile tissue of the LAVV cusps. Therefore it is relevant to further morphological knowledge of this valve, in order to build a solid foundation on the contractile microstructure in the different stages of the human development.


Subject(s)
Humans , Male , Female , Infant , Adult , Mitral Valve/anatomy & histology , Cadaver , Heart/anatomy & histology
7.
Goiânia; SES-GO; 02 jun 2020. 1-16 p. tab, graf, mapa.(Informe Epidemiológico Covid-19, 9).
Monography in Portuguese | LILACS (Americas), ColecionaSUS, CONASS, SES-GO | ID: biblio-1103353

ABSTRACT

Em 11 de março de 2020, a Organização Mundial da Saúde (OMS) classificou a Doença pelo Coronavírus 2019 (COVID-19) como uma pandemia. Isso significa que o vírus está circulando em todos os continentes e há ocorrência de casos oligossintomáticos, o que dificulta a identificação. Deste modo, principalmente no hemisfério sul, onde está o Brasil, os países devem se preparar para o outono/inverno com o objetivo de evitar casos graves e óbitos. Em Goiás, a partir de 04 de fevereiro até 02 de junho, foram notificados à Vigilância Epidemiológica 39.225 casos de COVID-19. Já foram confirmados 4.334 (11,1%) casos, destes 4.223 (97,6%) confirmados por critério laboratorial, 101 (2,2%) pelo critério clinícoepidemiológico. Do total de casos notificados 10.715 (27,3%) foram descartados e 24.176 (61,6%) continuam como suspeitos


On March 11, 2020, the World Health Organization (WHO) classified Coronavirus Disease 2019 (COVID-19) as a pandemic. This means that the virus is circulating on all continents and there are oligosymptomatic cases, which makes it difficult to identify. Thus, especially in the southern hemisphere, where Brazil is located, countries should prepare for autumn/winter in order to avoid severe cases and deaths. In Goiás, from February 4 to June 2, 39,225 cases of COVID-19 were reported to the Epidemiological Surveillance. A total of 4,334 (11.1%) cases, of these 4,223 (97.6%) confirmed by laboratory criteria, 101 (2.2%) by the clinicoepidemiological criterion. Of the total number of reported cases 10,715 (27.3%) were discarded and 24,176 (61.6%) remain as suspects


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Coronavirus Infections/mortality , Coronavirus Infections/prevention & control , Coronavirus Infections/epidemiology
8.
Goiânia; SES-GO; 12 maio 2020. 1-9 p. tab, graf, mapa.(Informe Epidemiológico Covid-19, 6).
Monography in Portuguese | LILACS (Americas), ColecionaSUS, Inca, CONASS, SES-GO | ID: biblio-1103147

ABSTRACT

Em 11 de março de 2020, a Organização Mundial da Saúde (OMS) classificou a Doença pelo Coronavírus 2019 (COVID-19) como uma pandemia. Isso significa que o vírus está circulando em todos os continentes e há ocorrência de casos oligossintomáticos, o que dificulta a identificação. Deste modo, principalmente no hemisfério sul, onde está o Brasil, os países devem se preparar para o outono/inverno com o objetivo de evitar casos graves e óbitos. Em Goiás, a partir de 04 de fevereiro até esta data, foram notificados à Vigilância Epidemiológica 17.243 casos de COVID-19. Dos quais 1.114 (6,4%) foram confirmados, 4.029 (23,3%) descartados e 12.100 (70,3%) continuam como suspeitos nos sistemas de informação (ESUS VE e SIVEP Gripe) aguardando encerramento pelos municípios de residência


On March 11, 2020, the World Health Organization (WHO) classified Coronavirus Disease 2019 (COVID-19) as a pandemic. This means that the virus is circulating on all continents and there are oligosymptomatic cases, which makes it difficult to identify. Thus, especially in the southern hemisphere, where Brazil is located, countries should prepare for autumn/winter in order to avoid severe cases and deaths. In Goiás, from February 4 to this date, 17,243 cases of COVID-19 were reported to the Epidemiological Surveillance. Of which 1,114 (6.4%) were confirmed, 4,029 (23.3%) discarded and 12,100 (70.3%) remain as suspects in the information systems (ESUS VE and SIVEP Gripe) awaiting closure by the municipalities of residence.


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Coronavirus Infections/mortality , Coronavirus Infections/prevention & control , Coronavirus Infections/epidemiology
9.
Goiânia; SES-GO; 21 maio 2020. 1-10 p. tab, graf, mapa.(Informe Epidemiológico Covid-19, 7).
Monography in Portuguese | LILACS (Americas), ColecionaSUS, CONASS, SES-GO | ID: biblio-1103227

ABSTRACT

Em 11 de março de 2020, a Organização Mundial da Saúde (OMS) classificou a Doença pelo Coronavírus 2019 (COVID-19) como uma pandemia. Isso significa que o vírus está circulando em todos os continentes e há ocorrência de casos oligossintomáticos, o que dificulta a identificação. Deste modo, principalmente no hemisfério sul, onde está o Brasil, os países devem se preparar para o outono/inverno com o objetivo de evitar casos graves e óbitos. Em Goiás, a partir de 04 de fevereiro até esta data, foram notificados à Vigilância Epidemiológica 22.857 casos de COVID-19. Dos quais 1.846 (8,1%) foram confirmados, 5.352 (23,4%) descartados e 15.659 (68,5%) continuam como suspeitos.


On March 11, 2020, the World Health Organization (WHO) classified Coronavirus Disease 2019 (COVID-19) as a pandemic. This means that the virus is circulating on all continents and there are oligosymptomatic cases, which makes it difficult to identify. Thus, especially in the southern hemisphere, where Brazil is located, countries should prepare for autumn/winter in order to avoid severe cases and deaths. In Goiás, from February 4 to this date, 22,857 cases of COVID-19 were reported to the Epidemiological Surveillance. Of which 1,846 (8.1%) were confirmed, 5,352 (23.4%) discarded and 15,659 (68.5%) remain as suspects.


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Coronavirus Infections/mortality , Coronavirus Infections/transmission , Coronavirus Infections/epidemiology
10.
Goiânia; SES-GO; 28 maio 2020. 1-13 p. graf, tab, mapa.(Informe Epidemiológico Covid-19, 8).
Monography in Portuguese | LILACS (Americas), ColecionaSUS, CONASS, SES-GO | ID: biblio-1103349

ABSTRACT

Em 11 de março de 2020, a Organização Mundial da Saúde (OMS) classificou a Doença pelo Coronavírus 2019 (COVID-19) como uma pandemia. Isso significa que o vírus está circulando em todos os continentes e há ocorrência de casos oligossintomáticos, o que dificulta a identificação. Deste modo, principalmente no hemisfério sul, onde está o Brasil, os países devem se preparar para o outono/inverno com o objetivo de evitar casos graves e óbitos. Em Goiás, a partir de 04 de fevereiro até 26 de maio, foram notificados à Vigilância Epidemiológica 29.228 casos de COVID-19. Dos quais 2.671 (9,1%) foram confirmados, 7.891 (27%) descartados e 15.659 (63,9%) continuam como suspeitos


On March 11, 2020, the World Health Organization (WHO) classified Coronavirus Disease 2019 (COVID-19) as a pandemic. This means that the virus is circulating on all continents and there are oligosymptomatic cases, which makes it difficult to identify. Thus, especially in the southern hemisphere, where Brazil is located, countries should prepare for autumn/winter in order to avoid severe cases and deaths. In Goiás, from February 4 to May 26, 29,228 cases of COVID-19 were reported to the Epidemiological Surveillance. Of which 2,671 (9.1%) were confirmed, 7,891 (27%) discarded and 15,659 (63.9%) remain as suspects


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Coronavirus Infections/mortality , Coronavirus Infections/prevention & control , Coronavirus Infections/epidemiology
11.
Goiânia; SES-GO; maio 2020. 1-42 p. ilus, tab.
Non-conventional in Portuguese | LILACS (Americas), ColecionaSUS, CONASS, SES-GO | ID: biblio-1096093

ABSTRACT

O surto da doença respiratória causada pelo novo coronavírus (SARS-CoV-2) aconteceu na cidade de Wuhan, capital da província de Hubei, na China, em dezembro de 2019, a qual disseminou-se de forma acelerada e, logo, atingiu mais de uma centena de países dos cinco continentes. Em 12 de março de 2020, a situação foi caracterizada como pandemia pela Organização Mundial de Saúde (OMS, 2020). Em razão da disseminação o do Coronavírus pelo mundo, o Ministério da Saúde declarou Emergência de Saúde Pública de Importância Nacional (ESPIN) em decorrência da infecção pelo novo coronavírus (COVID-19) e estabeleceu o Centro de Operações de Emergência em Saúde Pública (COE-COVID-19) como mecanismo de gestão coordenada da resposta à ESPIN no país (BRASIL, 2020a). Seguindo a linha mundial, o Ministério da Saúde elaborou e publicou "Plano de Contingência Nacional para Infecção Humana pelo Novo Coronavírus COVID-19" para organizar a detecção, monitoramento e resposta dos serviços de saúde à doença (BRASIL, 2020b). O Estado de Goiás instituiu o Centro de Operações Estratégicas de Saúde Pública (COE) em 18 de fevereiro de 2020 (GOIÁS, 2020a). E, seguindo as orientações nacionais, propõe o presente PLANO ESTADUAL DE CONTINGÊNCIA PARA O ENFRENTAMENTO DA DOENÇA PELO CORONAVÍRUS (COVID-19), a fim de organizar e fortalecer as políticas públicas de saúde, visto que, para que atinjam eficácia e eficiência, é necessário atuação conjunta e ordenada dos entes federados, bem como dos setores públicos e privados.


The outbreak of respiratory disease caused by the new coronavirus (SARS-CoV-2) occurred in Wuhan city, capital of Hubei province, China, in December 2019, which spread rapidly and thus reached more than a hundred countries on five continents. On March 12, 2020, the situation was characterized as a pandemic by the World Health Organization (WHO, 2020). Due to the spread of Coronavirus around the world, the Ministry of Health declared a Public Health Emergency of National Importance (ESPIN) due to infection by the new coronavirus (COVID-19) and established the Center for Emergency Operations in Public Health (COE-COVID-19) as a mechanism for coordinated management of the response to ESPIN in the country (BRASIL, 2020a). Following the global line, the Ministry of Health elaborated and published "National Contingency Plan for Human Infection by the New Coronavirus COVID-19" to organize the detection, monitoring and response of health services to the disease (BRASIL, 2020b). The State of Goiás established the Center for Strategic Operations of Public Health (COE) on February 18, 2020 (GOIÁS, 2020a). And, following the national guidelines, it proposes this State CONTINGENCY PLAN FOR COPING WITH CORONAVIRUS DISEASE (COVID-19), in order to organize and strengthen public health policies, since, in order to achieve effectiveness and efficiency, joint and orderly action of federal entities, as well as public and private sectors, is necessary.


Subject(s)
Humans , Male , Female , Pregnancy , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Coronavirus Infections/complications , Coronavirus Infections/diagnosis , Coronavirus Infections/prevention & control , Coronavirus Infections/therapy , Coronavirus Infections/transmission
12.
Univ. salud ; 22(1): 91-95, ene.-abr. 2020. tab
Article in Spanish | LILACS (Americas), COLNAL | ID: biblio-1094584

ABSTRACT

Introducción: La Organización Mundial de la Salud (OMS) establece los patrones de crecimiento de niños menores de 5 años. Colombia adoptó indicadores antropométricos y puntos de corte para clasificar el estado nutricional. Sin embargo, para desnutrición se considera Peso/Talla en vez del Índice de Masa Corporal (IMC). Objetivo: Identificar la prevalencia de malnutrición en menores de 5 años del área urbana del municipio de Palermo, Huila (Colombia), comparando los resultados con los patrones de la OMS y resolución 2465 de 2016 en el parámetro IMC/Edad. Materiales y métodos: Estudio de corte transversal, con enfoque analítico con 254 niños menores de 5 años del municipio de Palermo. Resultados: Según IMC/edad el 11,81% de los menores presentaron algún tipo de malnutrición: 1,9% desnutrición y 9,8% sobrepeso y obesidad. Un 25,5% estuvieron en riesgo de presentarlo, siendo mayor el sobrepeso (17,7%). Según parámetros OMS el 12,2% presentaron malnutrición: 9,8% por exceso y 2,4% por déficit. El 18,5% y 7,9% tuvieron riesgo de sobrepeso y bajo peso respectivamente. Conclusión: No existen diferencias al comparar la clasificación nutricional entre la Resolución y los parámetros de la OMS.


Introduction: The World Health Organization (WHO), has established the growth patterns of children under 5 years of age. Colombia has adopted anthropometric indicators and cut-off points to classify nutritional status. However, weight/height are the only measurements taken into account for defining malnutrition, instead of Body Mass Index (BMI). Objective: To identify malnutrition prevalence in children who are younger than 5 years of age and live in the metropolitan area of the municipality of Palermo-Huila (Colombia), comparing the results with the WHO reference standards and with the IMC/Age parameter of Resolution 2465 of 2106. Materials and methods: A cross-sectional study with an analytical approach was conducted on 254 children younger than 5 years old from Palermo. Results: According to the BMI/Age parameter 11.81% of the children showed some nutrition problem: 1.9% malnutrition and 9.8% overweight and obesity. 25.5% of children were at risk of having some type of malnutrition, with the risk of overweight (17.7%) being the highest. According to WHO parameters, 12.2% of child participants showed malnutrition: 9.8% due to excess and 2.4% because of a deficient intake of nutrients. It was observed that 18,5% and 7,9% of the minors were at risk of being overweight and underweight, respectively. Conclusions: There are no differences when comparing the nutritional classification of the Resolution with the one based on the WHO parameters.


Subject(s)
Infant , Child, Preschool , Malnutrition , Caregivers , Overweight , Social Determinants of Health , Obesity
13.
Arch. argent. pediatr ; 118(2): 89-: I-94, II, abr. 2020. tab, ilus
Article in English, Spanish | LILACS (Americas), BINACIS | ID: biblio-1099856

ABSTRACT

Introducción. La fiebre en pediatría es motivo de consulta frecuente. El objetivo fue evaluar los conocimientos, actitudes y temores de los padres ante la fiebre de sus hijos.Material y métodos. Estudio observacional, analítico, transversal. En 2018, se realizó una encuesta a padres de niños de entre 6 meses y 5 años que asistieron al Hospital de Niños Ricardo Gutiérrez de la Ciudad de Buenos Aires.Se analizó la asociación entre las variables sociodemográficas y los conocimientos, actitudes y temores frente al cuadro febril.Resultados. Se realizaron 201 encuestas. El 56,7 % de los padres consideró que la fiebre era mala para la salud. El 37 % definió fiebre entre 37 °C y 37,5 °C, y el 59 %, 38-38,5 ºC. La media de temperatura considerada grave fue 39,2 °C (desvío estándar 0,69). El 93 % de los cuidadores utilizaba medidas físicas; el 97 % administraba antitérmicos y el 14,5 % los alternaba. Los temores a las consecuencias fueron, en el 82 %, convulsiones; en el 41 %, deshidratación; en el 18 %, daño cerebral y, en el 12 %, muerte. El 86,5 % despertaba a sus hijos para administrarles antitérmico. En el estrato de mayor instrucción materna, fue menor el temor a la fiebre (odds ratio0,5; intervalo de confianza del 95 %: 0,28-0,91).Conclusiones. Un tercio de los encuestados consideró fiebre valores bajos de temperatura. El temor a la fiebre fue elevado y el nivel de instrucción materna podría mitigarlo.


Introduction. In pediatrics, fever is a common reason for consultation. The objective was to assess parental knowledge, behaviors, and fears in the management of fever in their children.Materials and methods. Observational, analytical, cross-sectional study. In 2018, a survey was administered to the parents of children aged 6 months to 5 years who attended Hospital de Niños Ricardo Gutiérrez, in the Autonomous City of Buenos Aires. The association between sociodemographic outcome measures and knowledge, behaviors, and fears in cases of fever was analyzed.Results. A total of 201 surveys were completed: 56.7 % of parents considered that fever was bad for health; 37 % defined fever between 37 °C and 37.5 °C, and 59 %, between 38 °C and 38.5 °C. The mean temperature considered severe was 39.2 °C (standard deviation: 0.69). Physical methods were used by 93 % of caregivers; 97 % administered antipyretic agents, and 14.5 % used alternating agents. Fears of consequences included seizures in 82 %, dehydration in 41 %, brain damage in 18 %, and death in 12 %. Also, 86.5 % woke up their children to give them an antipyretic agent. Among the higher maternal education level, fear of fever was lower (odds ratio: 0.5; 95 % confidence interval: 0.28-0.91).Conclusions. One-third of survey respondents considered low body temperature values as fever. Fear of fever was high, and the level of maternal education may mitigate it.


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Adult , Health Knowledge, Attitudes, Practice , Disease Management , Fever/therapy , Parents , Cross-Sectional Studies , Surveys and Questionnaires , Antipyretics/therapeutic use , Fever/diagnosis
14.
Arch. argent. pediatr ; 118(2): 95-101, abr. 2020. tab, ilus
Article in English, Spanish | LILACS (Americas), BINACIS | ID: biblio-1099857

ABSTRACT

Introducción. El objetivo fue evaluar la concentración de vitamina D en niños sanos de 12 a 24 meses suplementados con vitamina D (400 UI/día) durante el primer año.Métodos. Estudio descriptivo transversal entre junio de 2015 y mayo de 2016 en Estambul. Se incluyó a niños de 12 a 24 meses en seguimiento en la clínica del niño sano y con suplementación con vitamina D durante el primer año. Se midió calcio, fósforo, fosfatasa alcalina, hormona paratiroidea y 25-hidroxivitamina D [25(OH)D]. Se definió suficiencia (>20 ng/ml), insuficiencia (15-20 ng/ml) y deficiencia (<15 ng/ml) de vitamina D.Resultados. El estudio incluyó 197 niños. El 26,9 % (n = 53) siguió recibiendo suplementación después del año (dosis media: 491 ± 267 UI/día). La concentración media de 25(OH)D fue 38,0 ± 13,9 ng/ml. La ingesta regular de vitamina D en menores de un año (p = 0,008) y la continuación de suplementación después del año (p = 0,042) aumentaron la concentración de 25(OH)D en niños de 12 a 24 meses. Hubo deficiencia en 4,1 % e insuficiencia en 7,1 %. El nivel educativo materno (p = 0,009) y la leche maternizada (p = 0,012) fueron factores protectores contra deficiencia o insuficiencia.Conclusiones. La concentración de 25(OH)D era suficiente en el 88,8 % de los niños de 12 a 24 meses con suplementación con vitamina D (400 UI/día) durante el primer año. Los niños sanos de 12 a 24 meses con una suplementación correcta de vitamina D en el primer año podrían no requerir suplementación.


Introduction. The aim of this study was to evaluate vitamin D levels between 12-24 month-old healthy children supplemented with vitamin D (400 IU/day) during the first year.Methods. Descriptive-sectional study conducted between June 2015, and May 2016, in Istanbul (latitude 41ºN). Children aged 12-24 months followed up by the well-child clinic who had vitamin D supplementation in the first year were included in the study. The levels of calcium, phosphorus, alkaline phosphatase, parathyroid hormone and 25-hydroxyvitamin D [25(OH)D] were measured. Vitamin D status was defined as >20 ng/mL: sufficiency, 15-20 ng/mL: insufficiency and <15 ng/mL: deficiency.Results. The study was completed with 197 children. 26.9 % of children (n = 53) went on receiving supplementation after one year (mean dose 491 ± 267 IU/day). The mean 25(OH)D level was 38.0 ± 13.9 ng/mL. It was found that regular vitamin D intake under one year of age (p = 0.008) and continued support after one year of age (p = 0.042) increased level of 25(OH)D in children aged 12-24 months. Vitamin D deficiency was found in 4.1 % and vitamin D insufficiency in 7.1 %. Mother's education (p = 0.009) and use of formula (p = 0.012) were protective factors in relation to development of vitamin D deficiency or insufficiency.Conclusions. The level of 25(OH)D was sufficient in 88.8 % of children aged 12-24 months receiving 400 IU/day vitamin D supplementation in the first year. Vitamin D supplementation could not be required in healthy children aged 12-24 months who received properly vitamin D supplementation in the first year.


Subject(s)
Humans , Male , Female , Infant , Vitamin D/blood , Dietary Supplements , Turkey , Vitamin D/administration & dosage , Vitamin D/therapeutic use , Vitamin D Deficiency , Epidemiology, Descriptive , Cross-Sectional Studies , Statistical Analysis
15.
Arch. argent. pediatr ; 118(2): 135-138, abr. 2020. tab
Article in English, Spanish | LILACS (Americas), BINACIS | ID: biblio-1100249

ABSTRACT

El daño renal agudo es causa de morbilidad en niños diabéticos en países en vías de desarrollo, especialmente, en pacientes con cetoacidosis diabética. El objetivo de esta investigación fue identificar factores de riesgo para daño renal agudo en pacientes con cetoacidosis diabética. Se realizó un estudio de cohorte retrospectiva. Se incluyeron 50 pacientes diabéticos con cetoacidosis; el 54 % desarrollaron daño renal; en ellos, los niveles de glucosa y ácido úrico fueron mayores (541 mg/dl contra 407 mg/dl, p = 0,014, y 8,13 mg/dl contra 5,72 mg/dl, p = 0,015, respectivamente). El ácido úrico mayor de 6,5 mg/dl demostró un odds ratio de 6,910 (p = 0,027) para daño renal. En conclusión, la hiperuricemia fue un factor de riesgo para el desarrollo de daño renal agudo en estos pacientes. Son necesarios estudios prospectivos para determinar el papel del ácido úrico en la patogénesis del daño renal agudo en pacientes diabéticos.


Acute kidney injury is a cause of morbidity in children with diabetes in developing countries, especially in patients with diabetic ketoacidosis. The objective of this study was to identify the risk factors for acute kidney injury in patients with diabetic ketoacidosis. This was a retrospective cohort study. A total of 50 patients with diabetic ketoacidosis were included; 54 % developed kidney injury. These had higher glucose and uric acid levels (541 mg/dL vs. 407 mg/dL, p = 0.014 and 8.13 mg/dL vs. 5.72 mg/dL, p = 0.015, respectively). Uric acid levels above 6.5 mg/dL showed an odds ratio of 6.910 (p= 0.027) for kidney injury. To conclude, hyperuricemia was a risk factor for acute kidney injury in these patients. Prospective studies are required to determine the role of uric acid in the pathogenesis of acute kidney injury in patients with diabetes.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Diabetic Ketoacidosis/diagnosis , Acute Kidney Injury , Uric Acid , Statistical Analysis , Retrospective Studies , Risk Factors , Hyperuricemia
16.
Arch. argent. pediatr ; 118(2): e162-e165, abr. 2020. ilus
Article in Spanish | LILACS (Americas), BINACIS | ID: biblio-1100422

ABSTRACT

Los sarcomas de partes blandas en menores de 2 años son infrecuentes. Durante 2007-2017, 445 pacientes con sarcomas de partes blandas fueron tratados en nuestra Institución; 6 (el 0,5 %) eran menores de 2 años. Se analizaron los resultados clínicos y oncológicos en este grupo. La edad media de diagnóstico fue 15 meses. Cuatro eran varones y 2, mujeres. El seguimiento promedio fue 29 meses. El fibrosarcoma (n = 4) fue la variedad más frecuente. Cinco fueron tratados con cirugía de conservación del miembro; al restante se le realizó amputación. Todos realizaron tratamiento adyuvante con quimioterapia. La supervivencia a 24 meses fue del 100 %. Dos pacientes presentaron recidiva local; ambos casos, antes de los 24 meses.El tratamiento quirúrgico asociado a la quimioterapia impresiona ser la mejor opción terapéutica. La proporción de recurrencia local es alta para este grupo de pacientes luego de la cirugía de conservación del miembro.


Soft tissue sarcomas in children under 2 years of age are infrequent. During 2007-2017, a total of 445 patients diagnosed with soft tissue sarcomas were treated at our institution, 6 (0.5 %) were under 2 years. We analysed clinical and oncologic outcomes in this select group. The mean age of diagnosis was 15 months. Four patients were male and 2 female. The mean follow-up time was 29 months. Fibrosarcoma (n = 4) was the most frequent diagnosis. Five patients were treated with limb salvage surgery, and the remaining one had to undergo amputation. All patients received adjuvant treatment with chemotherapy. The 24-month survival rate was 100 %. Two patients presented a local recurrence before 24-months follow-up. Surgical treatment associated with chemotherapy seems to be the best therapeutic option. Local recurrence rate after limb salvage surgery is high for this group of patients


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Sarcoma/surgery , Drug Therapy , Rhabdomyosarcoma/surgery , Rhabdomyosarcoma/therapy , Sarcoma/radiotherapy , Sarcoma/therapy , Retrospective Studies
17.
Arch. argent. pediatr ; 118(2): e174-e177, abr. 2020.
Article in English, Spanish | LILACS (Americas), BINACIS | ID: biblio-1100429

ABSTRACT

La linfohistiocitosis hemofagocítica (LHH) puede ser primaria (hereditaria) o secundaria a infecciones, tumores malignos, trastornos reumatológicos, síndromes de inmunodeficiencia y metabolopatías. Se informaron casos de intolerancia a la proteína lisinúrica, deficiencia de múltiples sulfatasas, galactosemia, enfermedad de Gaucher, síndrome de Pearson y galactosialidosis. No se sabe cómo se desencadena la LHH en las metabolopatías. Se diagnosticó LHH en un lactante de 2 meses con letargo, palidez, alimentación deficiente, hepatoesplenomegalia, fiebre y pancitopenia, y se instauró el protocolo HLH-2004. Se realizaron, en conjunto, análisis para detectar mutaciones genéticas y pruebas metabólicas; los resultados fueron negativos para las mutaciones genéticas de LHH primaria, pero se detectaron hiperamoniemia y concentración elevada de metilcitrato. Se diagnosticó acidemia propiónica. Aquí informamos sobre un caso de LHH secundaria a acidemia propiónica. Es posible la realización simultánea de pruebas de detección de trastornos metabólicos y de mutaciones genéticas para el diagnóstico temprano en los lactantes con LHH


Hemophagocytic lymphohystiocytosis (HLH) may be primary (inherited/familial) or secondary to infections, malignancies, rheumatologic disorders, immune deficiency syndromes and metabolic diseases. Cases including lysinuric protein intolerance, multiple sulfatase deficiency, galactosemia, Gaucher disease, Pearson syndrome, and galactosialidosis have previously been reported. It is unclear how the metabolites trigger HLH in metabolic diseases. A 2-month-old infant with lethargy, pallor, poor feeding, hepatosplenomegaly, fever and pancytopenia, was diagnosed with HLH and the HLH-2004 treatment protocol was initiated. Analysis for primary HLH gene mutations and metabolic screening tests were performed together; primary HLH gene mutations were negative, but hyperammonemia and elevated methyl citrate were detected. Propionic acidemia was diagnosed with tandem mass spectrometry in neonatal dried blood spot. We report this case of HLH secondary to propionic acidemia. Both metabolic disorder screening tests and gene mutation analysis may be performed simultaneously especially for early diagnosis in infants presenting with HLH.


Subject(s)
Humans , Male , Infant , Lymphohistiocytosis, Hemophagocytic/diagnosis , Propionic Acidemia/diagnosis , Pancytopenia , Splenomegaly , Lymphohistiocytosis, Hemophagocytic/drug therapy , Propionic Acidemia/drug therapy , Torpor , Continuous Renal Replacement Therapy , Hepatomegaly
18.
Arch. argent. pediatr ; 118(2): e183-e187, abr. 2020. ilus
Article in Spanish | LILACS (Americas), BINACIS | ID: biblio-1100433

ABSTRACT

La epilepsia refleja por agua caliente es un tipo de convulsión poco frecuente cuya fisiopatología se desconoce. Estas crisis reflejas suelen iniciarse pocos segundos tras el contacto con el agua y, comúnmente, a temperaturas de 37-48 ºC. Los automatismos y las crisis parciales complejas, con o sin generalización secundaria, son el modo de manifestación principal.La exploración neurológica y el electroencefalograma intercrítico no suelen presentar alteraciones, lo que puede condicionar un retraso en el diagnóstico, por lo que es fundamental la sospecha clínica.El tratamiento antiepiléptico se inicia cuando se asocia a otro tipo de epilepsia o cuando ciertas medidas sencillas, como el descenso de la temperatura del agua en el baño, no controlan las crisis. Es posible la desaparición espontánea. Cuando es necesaria la terapéutica farmacológica, existe, normalmente, buena respuesta.Se presenta el caso de un lactante con diagnóstico de epilepsia refleja por agua caliente.


Hot-water epilepsy is a rare type of seizure whose pathophysiology is unknown. These reflex seizures usually begin a few seconds after contact with water, commonly at temperatures between 37-48 ºC. Automations and complex partial crises, with or without secondary generalization, are the main manifestation mode of this type of reflex epilepsies.Neurological examination and intercritical electroencephalography are usually normal, which may condition a delay in diagnosis, and the clinical suspicion is fundamental.Antiepileptic treatment is initiated when associated with another type of epilepsy or when certain simple measures, such as lowering the water temperature in the bath, do not control crises. Spontaneous disappearance is possible; when pharmacological therapy is necessary, there is usually a good response.We present the case of an infant diagnosed with hot-water epilepsy.


Subject(s)
Humans , Male , Infant , Epilepsy, Reflex/diagnosis , Seizures , Baths , Epilepsy, Reflex/drug therapy , Hot Temperature
19.
Arch. argent. pediatr ; 118(2): e188-e190, abr. 2020. ilus
Article in Spanish | LILACS (Americas), BINACIS | ID: biblio-1100470

ABSTRACT

La invaginación intestinal es la causa más frecuente de obstrucción intestinal entre los 6 y los 36 meses de edad. La mayoría son idiopáticas. Se ha descrito la asociación entre la enfermedad celíaca y la invaginación intestinal en la población pediátrica. Se presenta el caso de un varón de 23 meses ingresado por estancamiento ponderal en cuyo estudio ecográfico se observaron invaginaciones íleo-ileales asintomáticas repetidas.


Intestinal intussusception is the most frequent cause of intestinal obstruction between 6 and 36 months of age, the majority being idiopathic. The association between celiac disease and intestinal intussusception in the pediatric population has been described. We present the case of a 23-month-old male admitted due to a failure to thrive. In his ultrasound study recurrent asymptomatic ileo-ileal invaginations were found


Subject(s)
Humans , Male , Infant , Celiac Disease/diagnosis , Intussusception/diagnostic imaging , Celiac Disease/diet therapy , Failure to Thrive , Diet, Gluten-Free , Intussusception/diet therapy
20.
Arch. argent. pediatr ; 118(2): s59-s63, abr. 2020. ilus, tab
Article in Spanish | LILACS (Americas), BINACIS | ID: biblio-1100502

ABSTRACT

El síndrome de lisis tumoral representa una complicación potencialmente letal provocada por la liberación masiva de ácidos nucleicos, potasio y fosfato hacia la circulación como resultado de la lisis de células neoplásicas, las cuales se caracterizan por una rápida capacidad de proliferación y alta sensibilidad a fármacos. Esto puede ocurrir de forma espontánea antes del inicio del tratamiento y agravarse luego de haberse iniciado la quimioterapia. Presenta una alta mortalidad. Su prevención continúa siendo la medida terapéutica más importante. El cuadro clínico se caracteriza por la existencia de trastornos del metabolismo hidroelectrolítico, en particular, hipercalemia, hiperfosfatemia e hiperuricemia y por la aparición de una lesión renal aguda. Una adecuada intervención terapéutica implica hidratación intravenosa y medidas para prevenir o corregir las alteraciones metabólicas. En este artículo, se proponen lineamientos para seguir tanto en la etapa diagnóstica como en el tratamiento de esta complicación.


The tumor lysis syndrome represents a potentially lethal complication caused by the massive release of nucleic acids, potassium and phosphate into the circulation as a result of the lysis of neoplastic cells, which are characterized by a rapid proliferation capacity and high sensitivity to drugs. This may occur spontaneously prior to the start of treatment, becoming worse after the initiation of chemotherapy. It presents a high mortality; its prevention continues being the most important therapeutic measure. The clinical picture is characterized by the existence of hydroelectrolytic metabolism disorders, in particular hyperkalemia, hyperphosphatemia and hyperuricemia and by the appearance of an acute renal lesion. Adequate therapeutic intervention involves intravenous hydration and measures to prevent or correct metabolic alterations. This article proposes guidelines to follow both in the diagnostic stage and in the treatment of this complication.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Tumor Lysis Syndrome/diagnosis , Tumor Lysis Syndrome/prevention & control , Tumor Lysis Syndrome/drug therapy , Risk Assessment , Hyperuricemia/drug therapy , Hyperphosphatemia/drug therapy , Hypercalcemia/drug therapy , Hypocalcemia/drug therapy
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