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2.
Acta cir. bras ; 32(9): 736-745, Sept. 2017. tab, graf
Article in English | LILACS | ID: biblio-886242

ABSTRACT

Abstract Purpose: To investigate dynamically the X-ray appearance of cervical degenerative disease induced by unbalanced dynamic and static forces in rats. Methods: A total of 60 Sprague Dawley rats were randomized into test (n=45) and control (n=15) groups, which were randomly subdivided into the one-, three- and six-month post-operative groups. The test group included 10, 15 and 20 rats at the respective corresponding post-operative stage and the control group included five rats at each time-point. By excising cervicodorsal muscles, interspinous ligaments and supraspinous ligament of rats in the test group, the balance of dynamic and static forces on cervical vertebrae was disrupted to establish a rat model of cervical degeneration. Spinal X-ray images were acquired, and intervertebral disc space and intervertebral foramen size were measured at one, three and six months post-operation. The results were analyzed and compared among groups. Results: Cervical dynamic and static imbalance accelerated the appearance of cervical degenerative disease on X-ray. Conclusion: Cervical degenerative disease may be induced by unbalanced dynamic and static forces in rats.


Subject(s)
Animals , Male , Rats , Intervertebral Disc Degeneration/diagnostic imaging , Biomechanical Phenomena , Random Allocation , Rats, Sprague-Dawley , Disease Models, Animal , Intervertebral Disc Degeneration/etiology
3.
Arq. bras. med. vet. zootec. (Online) ; 69(4): 941-947, jul.-ago. 2017. tab, ilus
Article in Portuguese | LILACS, VETINDEX | ID: biblio-876689

ABSTRACT

Objetivou-se com este trabalho descrever os aspectos de tomografia computadorizada de discos intervertebrais de cães da raça Dachshund com um ano de idade, assim como quantificar, qualificar e localizar a mineralização nos componentes do DIV e no espaço intervertebral da coluna vertebral. Dez cães dessa raça, com um ano de idade, foram submetidos à tomografia computadorizada (TC). Nas imagens de reconstrução sagital dos animais, procedeu-se à identificação de sete DIV em cada animal, entre as vértebras T9 e L3, totalizando a análise de 70 DIV. Entre os DIV mineralizados, a presença da alteração foi determinada quanto à localização no núcleo pulposo (NP), no anel fibroso (AF) e em AF/NP. Dos 70 DIV avaliados, 45 foram considerados como mineralizados. Entre os classificados como mineralizados, 20% (9/45), 17,8% (8/45) e 62,2% (28/45) estavam localizados nas regiões do NP, AF e AF/NP, respectivamente. A mineralização encontrada neste estudo esteve caracterizada por aumento de atenuação radiográfica com densidade mineral na topografia do DIV, havendo variações da localização e da radiodensidade de área calcificada entre animais e DIV no mesmo indivíduo. As alterações relativas à mineralização dos DIV podem ser classificadas tomograficamente quanto à localização da alteração no disco em AF, NP e AF/NP.(AU)


The objective was to describe CT imaging of calcified IVD in one-year-old Dachshunds, as well as describe the location in the soft tissue structures that make up the IVD. Ten one-year-old dogs underwent computed tomography (CT). In sagittal reconstruction images of animals, the identification of 70 IVD present in the spaces between L3 - T9 were performed. Among calcified IVDs, the presence of the change was determined as the location in the nucleus pulposus (NP), annulus fibrosus (AF) and both. Of a total of 70 evaluated IVDs, 45 were found to calcified and 25 not calcified. Among calcified discs, location was determined in nine (20%) in NP, eight discs (17.77%) in AF and 28 (62, 23%) NP & AF. Calcification in this study was characterized by increased radiographic attenuation mineral density in the IVD topography. There is variation in the location and radiodensity of calcified areas between animals and IVD in the same individual. Changes related to IVD calcification can be classified as tomographic location in AF, NP and NP & AF.(AU)


Subject(s)
Animals , Dogs , Intervertebral Disc Degeneration/diagnostic imaging , Intervertebral Disc Degeneration/veterinary , Tomography/veterinary , Spinal Diseases/veterinary
4.
Coluna/Columna ; 15(4): 325-329, Oct.-Dec. 2016. tab, graf
Article in English | LILACS | ID: biblio-828617

ABSTRACT

ABSTRACT Systematic review of the literature on the evaluation of images of degenerative changes of the spine and its clinical correlation. A systematic literature review was conducted, and the results evaluated for the presence of clinical correlation, as well as the type of imaging method used. The search terms were "Intervertebral Disc Degeneration", "Intervertebral disc", "Classification", "Anulus fibrosus", "Nucleus pulposus", "Lumbar spine", "Degenerative disc disease", "Degeneration", "Zygapophyseal Joint". We also assessed whether there were inter- and intraobserver agreement in the selected works and possible guidelines regarding the treatment and prognosis of patients. Of the 91 reviewed abstracts, 31 articles were selected that met the inclusion criteria. Six articles were related to the cervical spine, 13 to the lumbar spine and 12 were about changes not related specifically to a single segment of the spine. Articles that determined limiting values considered normal were also included, since variations were considered signs of degeneration or pathology. It was not possible to establish the relationship between the changes identified in imaging and the clinical history of patients, either define treatment and prognosis guidelines.


RESUMO Revisão sistemática da literatura de avaliação por imagem das alterações degenerativas da coluna e sua correlação clínica. A revisão sistemática da literatura foi realizada e seus resultados, avaliados com relação à presença de correlação clínica, assim como o tipo de método de imagem utilizado. Os termos de pesquisa foram "Intervertebral Disc Degeneration", "Intervertebral disc", "Classification", "Anulus fibrosus", "Nucleus pulposus", "Lumbar spine", "Degenerative disc disease", "Degeneration", "Zygapophyseal Joint". Também se avaliou se houve concordância inter e intraobservador nos trabalhos selecionados e possíveis orientações com relação ao tratamento e ao prognóstico dos pacientes. Dos 91 resumos revisados, foram selecionados 31 artigos que satisfizeram os critérios de inclusão. Seis artigos estavam relacionados com a coluna cervical, 13 com a coluna lombar e 12 versavam sobre alterações não relacionadas especificamente com um único segmento da coluna. Os artigos que determinaram valores limítrofes considerados normais também foram incluídos, uma vez que suas variações foram consideradas sinais de degeneração ou patologia. Não foi possível estabelecer a relação entre alterações identificadas nos exames de imagem e a história clínica dos pacientes, tampouco definir orientações de tratamento e prognóstico.


RESUMEN Revisión sistemática de la literatura sobre evaluación por imágenes de los cambios degenerativos de la columna y su correlación clínica. Fue realizada una revisión sistemática de la literatura y sus resultados evaluados cuanto a la presencia de correlación clínica, así como al tipo de método de imagen utilizado. Los términos de búsqueda fueron "Intervertebral Disc Degeneration", "Intervertebral disc", "Classification", "Anulus fibrosus", "Nucleus pulposus", "Lumbar spine", "Degenerative disc disease", "Degeneration", "Zygapophyseal Joint". Se evaluó también si había concordancia inter e intraobservador en los trabajos seleccionados, además de las posibles orientaciones en cuanto al tratamiento y al pronóstico de los pacientes. De los 91 resúmenes revisados, treinta y un artículos que cumplieron los criterios de inclusión fueron seleccionados. Seis artículos estaban relacionados con la columna cervical, 13 con la columna lumbar y 12 eran acerca de cambios no relacionados específicamente a un solo segmento de la columna vertebral. También se incluyeron artículos que determinaron valores límites considerados normales, ya que los cambios fueron considerados señales de degeneración o patología. No fue posible establecer la relación entre los cambios identificados en las imágenes y la historia clínica de los pacientes, tampoco definir orientaciones de tratamiento y pronóstico.


Subject(s)
Intervertebral Disc Degeneration/diagnostic imaging , Spinal Diseases/classification , Diagnostic Imaging/methods , Zygapophyseal Joint
5.
Article in English | WPRIM | ID: wpr-223658

ABSTRACT

BACKGROUND: We retrospectively evaluated the clinical and radiological outcomes of posterior lumbar interbody fusion (PLIF) with using a unilateral single cage and a local morselized bone graft. METHODS: Fifty three patients who underwent PLIF with a unilateral single cage filled with local morselized bone graft were enrolled in this study. The average follow-up duration was 31.1 months. The clinical outcomes were evaluated with using the visual analogue scale (VAS) at the pre-operative period, at 1 year post-operation and at the last follow-up, the Oswestry Disability Index, the Prolo scale and the Kim & Kim criteria at the last follow-up; the radiological outcomes were evaluated according to the change of bone bridging, the radiolucency, the instablity and the disc height. RESULTS: For the clinical evaluation, the VAS pain index, the Oswestry Disability Index, the Prolo scale and the Kim & Kim criteria showed excellent outcomes. For the the radiological evaluation, 52 cases showed complete bone union at the last follow-up. Regarding the complications, only 1 patient had cage breakage during follow-up. CONCLUSIONS: PLIF using a unilateral single cage filled with a local morselized bone graft has the advantages of a shorter operation time, less blood loss and a shorter hospital stay, as compared with the PLIF using bilateral cages, for treating degenerative lumbar spine disease. This technique also provides excellent outcomes according to the clinical and radiological evaluation.


Subject(s)
Adult , Aged , Blood Loss, Surgical , Bone Transplantation/methods , Female , Follow-Up Studies , Humans , Intervertebral Disc Degeneration/diagnostic imaging , Lumbar Vertebrae/pathology , Male , Middle Aged , Prosthesis Implantation/methods , Retrospective Studies , Spinal Fusion/methods , Spinal Stenosis/surgery , Spondylolisthesis/surgery , Time and Motion Studies , Treatment Outcome
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