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1.
Arq. bras. oftalmol ; 82(1): 68-71, Jan.-Feb. 2019. graf
Article in English | LILACS | ID: biblio-973863

ABSTRACT

ABSTRACT The authors describe an unusual association between posterior keratoconus and iris atrophy, confirmed by a complete ocular evaluation, scheimpflug imaging and pachymetric curve. A hypothesis for concomitant findings is discussed.


RESUMO Os autores descrevem a rara associação entre ceratocone posterior e atrofia de íris, confirmada por avaliação oftalmológica completa, imagens de scheimpflug e curva paquimétrica. Sugere-se uma hipótese que explique a concomitância de ambas as alterações.


Subject(s)
Humans , Female , Middle Aged , Iris/pathology , Iris Diseases/complications , Keratoconus/complications , Astigmatism/complications , Astigmatism/pathology , Atrophy , Amblyopia/complications , Amblyopia/pathology , Corneal Topography/methods , Corneal Pachymetry/methods , Keratoconus/pathology
2.
Arq. bras. oftalmol ; 79(5): 328-329, Sept.-Oct. 2016. graf
Article in English | LILACS | ID: biblio-827975

ABSTRACT

ABSTRACT A 42-year-old woman was admitted to our clinic with a complaint of glare in both eyes. Biomicroscopic examination of both the eyes revealed iris and lens colobomas in the inferior quadrant. Fundus examination of the right eye revealed an oval and gray inferotemporal optic pit and two choroid colobomas in the inferior quadrant. In the left eye, two choroid colobomas were detected that were inferior to the optic nerve head. Furthermore, a 21-year-old man presented to our clinic for a routine ophthalmologic examination. Bilateral biomicroscopic examination was normal. Fundus examination of the left eye revealed an oval and gray inferotemporal optic pit and a choroid coloboma that was inferior to the optic nerve head. Here we describe optic pits co-occurring with iris, lens, and choroidal colobomas. On the basis of these cases, a defect in the closure of the embryonic fissure is the most plausible etiology of the optic pit.


RESUMO Uma mulher de 42 anos de idade foi internada em nossa clínica com queixa de ofuscamento em ambos os olhos. O exame biomicroscópico revelou coloboma de íris e cristalino no quadrante inferior em ambos os olhos. O exame de fundo do olho direito revelou um fosseta óptica oval e acinzentada na região inferotemporal e dois colobomas coroide no quadrante inferior. No olho esquerdo, dois colobomas de coroide foram detectados inferiormente à da cabeça do nervo óptico. Outro homem de 21 anos apresentou-se em nossa clínica para um exame oftalmológico de rotina. O exame biomicroscópico foi normal, bilateralmente. O exame de fundo do olho esquerdo revelou uma fosseta oval e acinzentada de nervo óptico óptico inferotemporal e um coloboma coroide inferior à cabeça do nervo óptico. Nestes relatos nós descrevemos fossetas ópticas ocorrendo simultaneamente com colobomas de íris, cristalino, e coroide. Com base nestes casos, o defeito no fechamento da fissura embrionária é uma provável etiologia da fosseta óptica.


Subject(s)
Humans , Male , Female , Adult , Young Adult , Optic Disk/abnormalities , Coloboma/pathology , Iris/abnormalities , Choroid/abnormalities , Lens, Crystalline/abnormalities , Optic Disk/pathology , Optic Disk/diagnostic imaging , Fluorescein Angiography/methods , Visual Acuity , Coloboma/diagnostic imaging , Iris/pathology , Iris/diagnostic imaging , Choroid/pathology , Choroid/diagnostic imaging , Tomography, Optical Coherence/methods , Fundus Oculi , Lens, Crystalline/pathology , Lens, Crystalline/diagnostic imaging
3.
Arq. bras. oftalmol ; 79(2): 119-120, Mar.-Apr. 2016. graf
Article in English | LILACS | ID: lil-782796

ABSTRACT

ABSTRACT Bilateral acute depigmentation of the iris (BADI) is a new clinical entity of unknown etiology and is characterized by bilateral, symmetrical, and simultaneous depigmentation of the iris with focal or diffuse stromal atrophy; this condition generally has a good prognosis. We present a case of a 26-year-old woman who noted a spontaneous change in the iris color in both eyes in the last 2 months. The ophthalmological findings were atrophy of the iris stroma and pigmentation of the trabecular meshwork, without affecting the pigmented epithelium of the iris. Her intraocular pressure was normal and the visual acuity was 20/20 in both eyes.


RESUMO A despigmentação aguda bilateral da íris (DABI) é uma nova entidade clínica caracterizada pela despigmentação bilateral, simétrica e simultânea da íris, com atrofia focal ou difusa do seu estroma, geralmente com bom prognóstico. Apresentamos o caso de uma mulher de 26 anos de idade que procurou atendimento médico em nosso serviço com queixa de mudança espontânea na cor da íris de ambos os olhos nos últimos dois meses. Os achados oftalmológicos observados durante o exame clínico foram atrofia do estroma da íris e pigmentação da malha trabecular, sem afetar o epitélio pigmentado da íris. A pressão intraocular era normal e acuidade visual de 20/20 em ambos os olhos.


Subject(s)
Humans , Female , Adult , Pigment Epithelium of Eye/pathology , Pigmentation Disorders/diagnosis , Iris/pathology , Atrophy/diagnosis , Trabecular Meshwork/pathology , Acute Disease , Diagnosis, Differential
4.
Rev. bras. oftalmol ; 75(1): 58-60, jan.-fev. 2016. graf
Article in English | LILACS | ID: lil-771122

ABSTRACT

RESUMO Estudo realizado para descrever um caso da síndrome de Cogan Reese. Paciente do sexo feminino, 55 anos, com diagnóstico de síndrome de Cogan Reese. Melhor acuidade visual de 0,67 em olho direito e 0,2 em olho esquerdo. Pelo exame biomicroscópico não se detectou anormalidades no olho direito. No olho esquerdo haviam nódulos pigmentados na superfície anterior da íris, irregularidades corneanas e buraco iriano (pseudopolicoria). A pressão intra-ocular era 18 mmHg no olho esquerdo e havia atrofia óptica glaucomatosa no disco óptico. A paciente havia sido submetida à trabeculectomia três anos atrás. Recentemente o tratamento medicamentoso possibilitou o controle relativo da pressão intraocular. Gonioscopia revelou sinéquias anteriores periféricas. A microscopia especular eletrônica mostrou ICE-cells e baixa contagem de células. A cirurgia filtrante para tratamento do glaucoma usualmente tem sucesso quando realizada precocemente, mas ela pode falhar devido à endotelização da fístula pela membrana anormal do endotélio corneano. O tratamento medicamentoso foi efetivo apesar da falha na trabeculectomia.


ABSTRACT Study conducted to report a case of Cogan Reese syndrome. Female patient, 55 years old with diagnosis of Cogan Reese syndrome. Best visual acuity of 0.67 in the right eye and 0.2 in the left eye. By biomicroscopic examination there was no abnormalities in the right eye. In the left eye there were pigmented nodules on the anterior surface of the iris, corneal irregularities and iris hole (pseudopolycoria). The intraocular pressure was 18 mmHg in the left eye and there was glaucomatous optic atrophy of the optic disk. The patient had been subjected to trabeculectomy three years ago. Recently medical treatment allowed the relative control of intraocular pressure. Gonioscopy revealed peripheral anterior synechiae. Corneal specular microscopy showed ICE-cells and low cell count. Glaucoma filtering surgery is usually successful when done early, but it may fail due to endothelialization of the fistula by the abnormal corneal endothelium. Medical treatment was effective despite a fail trabeculectomy.


Subject(s)
Humans , Female , Middle Aged , Iris/pathology , Iridocorneal Endothelial Syndrome/diagnosis , Iris Diseases/diagnosis , Nevus, Pigmented/pathology , Trabeculectomy , Glaucoma/surgery , Treatment Failure , Slit Lamp Microscopy , Fundus Oculi , Gonioscopy , Intraocular Pressure/physiology
5.
Arq. bras. oftalmol ; 78(5): 305-309, Sep.-Oct. 2015. tab, ilus
Article in English | LILACS | ID: lil-761515

ABSTRACT

ABSTRACTPurpose:To investigate the relationship between quantitative iris parameters and the presence of keratoconus.Methods:Cross-sectional observational study that included 15 affected eyes of 15 patients with keratoconus and 26 eyes of 26 normal age- and sex-matched controls. Iris parameters (area, thickness, and pupil diameter) of affected and unaffected eyes were measured under standardized light and dark conditions using anterior segment optical coherence tomography (AS-OCT). To identify optimal iris thickness cutoff points to maximize the sensitivity and specificity when discriminating keratoconus eyes from normal eyes, the analysis included the use of receiver operating characteristic (ROC) curves.Results:Iris thickness and area were lower in keratoconus eyes than in normal eyes. The mean thickness at the pupillary margin under both light and dark conditions was found to be the best parameter for discriminating normal patients from keratoconus patients. Diagnostic performance was assessed by the area under the ROC curve (AROC), which had a value of 0.8256 with 80.0% sensitivity and 84.6% specificity, using a cutoff of 0.4125 mm. The sensitivity increased to 86.7% when a cutoff of 0.4700 mm was used.Conclusions:In our sample, iris thickness was lower in keratoconus eyes than in normal eyes. These results suggest that tomographic parameters may provide novel adjunct approaches for keratoconus screening.


RESUMOObjetivo:Investigar a relação entre os parâmetros quantitativos irianos e a presença de ceratocone.Métodos:Estudo observacional transversal com quinze olhos de 15 pacientes com ceratocone e 26 olhos de 26 indivíduos normais, pareados por idade e gênero. Parâmetros da íris (área, espessura e diâmetro da pupila) de olhos com ceratocone e olhos sem ceratocone foram medidos usando tomografia de coerência óptica do segmento anterior (AS-OCT), em condições padronizadas de alta luminosidade e ambiente escuro. Com o objetivo de maximizar a sensibilidade, especificidade e identificar o melhor ponto de corte na diferenciação entre ceratocone e indivíduos normais, foi realizada a análise quantitativa da curva característica operacional do receptor (ROC) dos parâmetros de espessura da íris.Resultados:A área e espessura da íris estavam reduzidas nos olhos de pacientes com ceratocone. Observamos que o melhor parâmetro para discriminar indivíduos normais de pacientes com ceratocone foi a espessura média na margem pupilar, tanto em condições de alta luminosidade quanto em ambiente escuro. O desempenho diagnóstico deste parâmetro foi avaliado pela análise quantitativa da área sob a curva ROC (AROC), mostrando AROC de 0,8256, com sensibilidade de 80,0% e especificidade de 84,6% usando um ponto de corte de 0,4125 milímetros de espessura da íris. A sensibilidade aumentou para 86,7%, com um corte de 0,4700 milímetros de espessura da íris.Conclusões:Na amostra deste estudo, a espessura da íris demostrou-se reduzida nos olhos com ceratocone. Estes resultados sugerem que os parâmetros tomográficos podem proporcionar novas informações no auxilio da triagem de pacientes com ceratocone.


Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , Iris/pathology , Keratoconus/pathology , Tomography, Optical Coherence , Cornea/pathology , Darkness , Epidemiologic Methods , Iris/physiopathology , Keratoconus/physiopathology , Lightning , Reference Values , Visual Acuity
6.
Rev. Esc. Enferm. USP ; 49(4): 626-631, July-Aug. 2015. tab, ilus
Article in English | LILACS, BDENF | ID: lil-757484

ABSTRACT

OBJECTIVETo compare the development of diabetes mellitus in subjects with and without the sign of the Cross of Andreas in the iris over a period of four years.METHODA prospective, descriptive study of quantitative approach. This cohort study had 91 patients without the disease, with and without the signal. The monitoring was conducted by means of the records in medical charts.RESULTSAt the end of the research, 28.2% of the group with the sign of the Cross of Andreas was diagnosed with diabetes and 56.5% had two or more episodes of impaired glucose tolerance. In the group without the sign, 4.4% was diagnosed with the disease and 24.5% had two or more episodes of glucose intolerance. There was a statistically significant difference between the groups regarding the development of the disease and glucose intolerance.CONCLUSIONThe group with the Cross of Andreas developed more glucose intolerance and diabetes than the group without the sign.


OBJETIVOEl objetivo de este trabajo fue comparar el desarrollo de la Diabetes Mellitus en individuos con y sin la señal de la cruz de Andreas en el iris en un período de cuatro años.MÉTODOEstudio prospectivo, descriptivo y con abordaje cuantitativo. Participaron de este estudio de cohorte 91 pacientes sin la enfermedad, con y sin la señal en el iris. El seguimiento fue llevado a cabo mediante registros en las fichas.RESULTADOSAl final de la investigación, el 28,2% del grupo con la señal de la cruz de Andreas fue diagnosticado con Diabetes y el 56,5% presentó dos o más episodios de intolerancia a la glucosa. En el grupo sin la señal, el 4,4% fue diagnosticado con la enfermedad y el 24,5% tuvo dos o más episodios de intolerancia a la glucosa. Hubo diferencia estadísticamente significativa entre los grupos en cuanto al desarrollo de la enfermedad (p=0,002) e intolerancia a la glucosa (p=0,004).CONCLUSIÓNEl grupo con la cruz de Andreas desarrolló más intolerancia a la glucosa y diabetes que el grupo sin esta señal en el iris.


OBJETIVODeste trabalho foi comparar o desenvolvimento do Diabetes Mellitus em indivíduos com e sem o sinal da Cruz de Andréas na íris em um período de quatro anos.MÉTODOEstudo prospectivo, descritivo e com abordagem quantitativa. Participaram deste estudo de coorte 91 pacientes sem a doença, com e sem o sinal na íris. O acompanhamento foi realizado por meio dos registros nos prontuários.RESULTADOSAo final da investigação, 28,2% do grupo com o sinal da Cruz de Andréas foi diagnosticado com Diabetes e 56,5% apresentou dois ou mais episódios de intolerância à glicose. No grupo sem o sinal, 4,4% foi diagnosticado com a doença e 24,5% teve dois ou mais episódios de intolerância à glicose. Houve diferença estatisticamente significativa entre os grupos quanto ao desenvolvimento da doença (p=0,002) e intolerância à glicose (p=0,004).CONCLUSÃOO grupo com a Cruz de Andréas desenvolveu mais intolerância à glicose e diabetes que o grupo sem este sinal na íris.


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Diabetes Mellitus/diagnosis , Iris/pathology , Diabetes Mellitus/metabolism , Glucose Intolerance , Longitudinal Studies , Prospective Studies
7.
SJO-Saudi Journal of Ophthalmology. 2013; 27 (4): 277-280
in English | IMEMR | ID: emr-143019

ABSTRACT

We report a case of large iris melanocytoma in a child diagnosed by fine needle aspiration biopsy. In this interventional case report, cytologic features typical of melanocytoma were obtained by fine needle aspiration biopsy [FNAB]. FNAB can be used in difficult diagnostic cases if a good sample is obtained, this technique has an accuracy of more than 99% in tumors larger than 3 mm; however, false-negative and false-positive results may be obtained. Its risk of local spread is very small, an advantage over incisional biopsy. The most common complication is intralesional hemorrhage and hyphema.


Subject(s)
Humans , Female , Iris Neoplasms/pathology , Biopsy, Fine-Needle/standards , Iris/pathology
8.
Indian J Ophthalmol ; 2011 July; 59(4): 312-314
Article in English | IMSEAR | ID: sea-136198

ABSTRACT

We report an unusual presentation of a case of Axenfeld-Rieger (A-R) syndrome. A 14-year-old male presented with gradual dimness of vision for 1 year and redness of left eye for 3 days. The patient had megalocornea with Haab's striae in the right eye and posterior embryotoxon in both the eyes. In the left eye, there was a white cord-like structure traversing the anterior chamber with adhesions to iris tissue along its course. On two antiglaucoma medications, his intraocular pressure (IOP) was 22 mm Hg in the right eye and 18 mm Hg in the left eye. Gonioscopy revealed a cord-like structure originating at the level of Schwalbe's line. He underwent right eye trabeculectomy with mitomycin-C. This case highlights a rare presentation of a strange cord-like structure, a rare presentation of A-R syndrome.


Subject(s)
Adolescent , Anterior Chamber/pathology , Anterior Eye Segment/abnormalities , Anterior Eye Segment/pathology , Anterior Eye Segment/physiopathology , Anterior Eye Segment/surgery , Cornea/abnormalities , Eye Abnormalities/pathology , Eye Abnormalities/physiopathology , Eye Abnormalities/surgery , Gonioscopy , Humans , Intraocular Pressure , Iris/pathology , Male , Mitomycin/therapeutic use , Tissue Adhesions/pathology , Trabeculectomy , Vision Disorders/etiology
9.
Article in English | WPRIM | ID: wpr-125050

ABSTRACT

PURPOSE: To compare conventional laser peripheral iridotomy (LPI) and LPI combined with laser peripheral iridoplasty in eyes with primary angle closure suspect (PACS) by assessment of anterior chamber dimensional changes using a Pentacam. METHODS: Forty-eight eyes of 24 subjects with bilateral PACS were recruited consecutively. Each eye was randomly allocated to treatment with conventional LPI, argon LPI only, or LPI plus iridoplasty, which consisted of simultaneous argon LPI and peripheral iridoplasty. Anterior chamber measurements were performed on each eye using a Pentacam, both before and after treatment. Mean anterior chamber depth (ACD), anterior chamber volume (ACV), and anterior chamber angle were measured, and topographic ACD analysis was performed. Results were compared between the two treatment groups. RESULTS: After treatment with either conventional LPI or LPI plus iridoplasty, the mean ACD and ACV increased significantly. Topographic ACD analysis revealed that the mid-to-peripheral ACD increase was significantly greater in the LPI plus iridoplasty group than in eyes treated with conventional LPI. Intraocular pressure changes and post-LPI complications did not differ between the groups. CONCLUSIONS: Compared with conventional LPI, our study showed that LPI plus iridoplasty improved the mid-to-peripheral ACD increase. This procedure may have a role as an adjunct for reducing angle closure by simultaneously eliminating pupillary and non-pupillary block components.


Subject(s)
Adult , Aged , Anterior Chamber/pathology , Diagnostic Techniques, Ophthalmological/instrumentation , Equipment Design , Female , Follow-Up Studies , Glaucoma, Angle-Closure/pathology , Gonioscopy , Humans , Intraocular Pressure , Iridectomy/methods , Iris/pathology , Laser Therapy/methods , Lasers, Solid-State , Male , Middle Aged , Prospective Studies , Tonometry, Ocular
10.
Article in English | WPRIM | ID: wpr-22607

ABSTRACT

We report a case of ciliary body melanocytoma in a Korean patient, which presented as an intermittently painful pigmented iris mass and was successfully managed by iridocyclectomy. A 52-year-old healthy man presented with an irregularly-shaped and heavily-pigmented mass at the iris root of his right eye. Visual acuity of the right eye was 20/20 with normal intraocular pressure. Ultrasound biomicroscopy showed a 1.5x1.3-mm ciliary-body mass with extension into the iris root. Iridocyclectomy with scleral resection under a lamellar scleral flap was performed, and the histopathologic features of the resected tissue were consistent with melanocytoma of the ciliary body. The patient's visual acuity remained 20/20 with good postoperative cosmesis. During one year of follow-up, no signs of tumor recurrence were seen, and the patient reported resolution of the intermittent ocular pain in the involved eye.


Subject(s)
Ciliary Body/surgery , Humans , Iris/pathology , Male , Middle Aged , Neoplasm Invasiveness/pathology , Nevus/pathology , Pain/physiopathology , Uveal Neoplasms/pathology
11.
Arq. bras. oftalmol ; 72(3): 302-307, May-June 2009. tab
Article in English | LILACS | ID: lil-521462

ABSTRACT

PURPOSE: To investigate biometrically the differences between plateau iris configuration (PIC) eyes and primary open angle glaucoma with narrow angle eyes. METHODS: A comparative study involving a case series with 20 eyes of 11 plateau iris configuration patients and 45 eyes of 27 primary open angle glaucoma with narrow angle eyes patients was done. The following measurements were taken: corneal curvature, central corneal thickness, anterior chamber depth, lens thickness (LT), axial length (AL), lens thickness and axial length ratio, lens position (LP) and relative lens position (RLP). RESULTS: The plateau iris configuration eyes presented a higher corneal cuvature value than primary open angle glaucoma with narrow angle eyes eyes but not with clinical and statistical difference (P=0.090). The plateau iris configuration eyes demonstrated a higher central corneal thickness, with statistical significance, when compared to primary open angle glaucoma with narrow angle eyes (P=0.010). Statistical significant difference between plateau iris configuration and primary open angle glaucoma with narrow angle eyes was found in axial length (21.69 ± 0.98 vs. 22.42 ± 0.89; P=0.003). No significant difference was found when anterior chamber depth (2.62 ± 0.23 vs. 2.71 ± 0.31; P=0.078), LT (4.67 ± 0.36 vs. 4.69 ± 0.45; P=0.975), LT/AL (2.16 ± 0.17 vs. 2.10 ± 0.21; P=0.569), LP (4.95 ± 0.25 vs. 5.06 ± 0.34; P=0.164) and RLP (0.23 ± 0.01 vs. 0.22 ± 0.14; P=0.348) were evaluated. CONCLUSION: The eyes with plateau iris configuration presented statistical significantly shorter axial length and higher central corneal thickness than primary open angle glaucoma with narrow angle eyes.


OBJETIVO: Comparar, biometricamente, olhos portadores de configuração da íris em platô (CIP) e olhos portadores de glaucoma primário de ângulo aberto com seio camerular estreito. MÉTODOS: Estudo prospectivo comparativo envolvendo 20 olhos de 11 pacientes portadores de íris em platô e 45 olhos de 27 pacientes portadores de glaucoma primário de ângulo aberto com seio camerular estreito. Os parâmetros avaliados foram: curvatura corneana, espessura central da córnea, profundidade central da câmara anterior, espessura do cristalino (EC), comprimento axial (CAx), relação entre a espessura do cristalino e o comprimento axial (EC/CAx), posição do cristalino (PC) e posição relativa do cristalino (PRC). RESULTADOS: Os olhos com íris em platô apresentaram valores ceratométricos superiores àqueles dos olhos com glaucoma primário de ângulo aberto com seio camerular estreito, embora sem diferença clínica ou estatística (P=0,090). Os olhos com configuração da íris em platô apresentaram maior espessura central da córnea com diferença estatisticamente significativa, quando comparados aos olhos com CIP (P=0,010). Diferença estatisticamente significativa foi encontrada entre os olhos com configuração da íris em platô e os olhos com glaucoma primário de ângulo aberto com seio camerular estreito no CAx (21,69 ± 0,98 vs. 22,42 ± 0,89; P=0,003). Não houve diferença significativa entre: profundidade central da câmara anterior (2,62 ± 0,23 e 2,71 ± 0,31; P=0,078); EC (4,67 ± 0,36 e 4,69 ± 0,45; P=0,975); EC/CAx (2,16 ± 0,17 e 2,10 ± 0,21; P=0,569); PC (4,95 ± 0,25 e 5,06 ± 0,34; P=0,164) e PRC (0,23 ± 0,01 e 0,22 ± 0,14; P=0,348). CONCLUSÃO: Os olhos com configuração da íris em platô possuem menor comprimento axial e maior espessura central da córnea em comparação aos olhos com glaucoma primário de ângulo aberto com seio camerular estreito, com significância estatística.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Cornea/pathology , Glaucoma, Open-Angle/pathology , Iris/pathology , Biometry , Chi-Square Distribution , Prospective Studies
12.
Indian J Ophthalmol ; 2009 Jan-Feb; 57(1): 61-3
Article in English | IMSEAR | ID: sea-70076

ABSTRACT

We describe the occurrence of bilateral iridocorneal endothelial (ICE) syndrome with glaucoma in a young girl with Down's syndrome. A 16-year-old girl with Down's syndrome was found to have secondary glaucoma in the right eye with features of progressive iris atrophy in both eyes. She was uncontrolled on maximum tolerable medical therapy for glaucoma. She underwent an uneventful trabeculectomy with mitomycin-C in her right eye. Scanning electron microscopy of the trabecular meshwork obtained in this case is described.


Subject(s)
Adolescent , Atrophy , Corneal Diseases/complications , Down Syndrome/complications , Endothelium, Corneal/pathology , Female , Functional Laterality , Glaucoma/etiology , Gonioscopy , Humans , Intraocular Pressure , Iris/pathology , Iris Diseases/complications , Karyotyping , Microscopy, Electron, Scanning , Syndrome , Trabecular Meshwork/surgery , Trabeculectomy
14.
Arq. bras. oftalmol ; 71(2): 265-268, mar.-abr. 2008. ilus
Article in English | LILACS | ID: lil-483039

ABSTRACT

Ocular complications in dengue fever are uncommon but may result in visual loss. The authors report the first documented case of a patient with dengue fever who presented with simultaneous bilateral acute angle closure glaucoma. The disease was confirmed by specific serological tests. Despite the treatment, severe visual impairment occurred in this case.


Complicações oculares são incomuns na dengue, mas podem resultar em perda visual. Os autores relatam o primeiro caso de um paciente com dengue que apresentou glaucoma agudo bilateral. Testes sorológicos confirmaram a doença. Apesar do tratamento, houve perda visual grave.


Subject(s)
Aged , Female , Humans , Severe Dengue/complications , Glaucoma, Angle-Closure/etiology , Acute Disease , Atrophy/diagnosis , Glaucoma, Angle-Closure/drug therapy , Iris/pathology
15.
Arq. bras. oftalmol ; 70(4): 683-688, jul.-ago. 2007. tab
Article in Portuguese | LILACS | ID: lil-461959

ABSTRACT

OBJETIVO: Descrever os resultados da cirurgia de catarata pela técnica de facoemulsificação em pacientes com uveíte. MÉTODOS: Foi realizado estudo retrospectivo pela análise de prontuários de 189 pacientes (242 olhos) com uveíte que foram submetidos a cirurgia de catarata pela técnica de facoemulsificação no Setor de Uveítes e Imunologia Ocular do Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canadá. Os dados foram coletados em fichas protocoladas com informações sobre sexo, idade, classificação da uveíte, descrição cirúrgica e exames pré e pós-operatórios. Os exames pré e pós-operatórios continham informações sobre a data do exame, a melhor acuidade visual corrigida, o exame biomicroscópico, a pressão intra-ocular, os procedimentos realizados e o tratamento em uso. RESULTADOS: A média de acompanhamento pós-operatório foi de 46,8 ± 31,2 meses. A média da acuidade visual pré-operatória encontrada foi de 20/100 e a média de acuidade visual pós-operatória encontrada foi de 20/40. Encontramos 145 olhos (59,5 por cento) com acuidade visual melhor ou igual a 20/40 e 26 olhos com piora da acuidade visual. A complicação per-operatória mais encontrada foi a ruptura de cápsula posterior com perda vítrea observada em 7 olhos (3 por cento do total de olhos). A recorrência da uveíte foi a complicação pós-operatória mais freqüente, sendo observada em 73 olhos (30,16 por cento). Outras complicações pós-operatórias observadas foram a atrofia iriana (28,51 por cento), hipertensão intra-ocular (28,09 por cento), membrana epirretiniana (26,44 por cento), opacidade de cápsula posterior (19 por cento), edema macular cistóide (13,63 por cento), hipotonia ocular (12,80 por cento), atrofia do disco óptico (8,67 por cento) e sinéquias posteriores (6,61 por cento). CONCLUSÕES: A cirurgia de catarata pela técnica de facoemulsificação é considerada segura e eficaz em pacientes com uveíte. Observamos um bom prognóstico visual no período...


PURPOSE: To report outcomes of cataract extraction by phacoemulsification in patients with uveitis. METHODS: We retrospectively reviewed the charts of 189 patients (242 eyes) with uveitis who underwent cataract extraction by phacoemulsification at the Uveitis and Ocular Immunology Unit of McGill University Health Centre, Montreal, Quebec, Canada. RESULTS: Average follow-up was 46 ± 31.2 months. Average preoperative visual acuity was 20/100 and average postoperative visual acuity was 20/40. Hundred and forty-six eyes (59.9 percent) attained visual acuity better than 20/40. Visual loss occurred in 26 eyes. The most common peroperative complication was posterior capsule rupture with vitreous loss seen in 7 eyes (3 percent). Recurrence of uveitis was the most common postoperative complication seen in 73 eyes (30.16 percent). Other postoperative complications included iris atrophy (28.51 percent), ocular hypertension (28.09 percent), epiretinal membrane (26.44 percent), posterior capsule opacification (19 percent), cystoid macular edema (13.63 percent), ocular hypotony (12.80 percent), optic disc atrophy (8.67 percent) and posterior synechiae (6.61 percent). CONCLUSIONS: Cataract extraction by phacoemulsification is safe in patients with uveitis. Successful visual results are observed in long-term follow-up despite the prevalence of recurrence of uveitis, posterior capsule opacification and macular abnormalities. To the best of our knowledge this is the largest series presented to date.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Lens Implantation, Intraocular , Phacoemulsification/adverse effects , Uveitis/complications , Atrophy , Brazil , Follow-Up Studies , Intraocular Pressure/physiology , Iris/pathology , Lenses, Intraocular , Lens Capsule, Crystalline/injuries , Ocular Hypertension/etiology , Recurrence , Retrospective Studies , Treatment Outcome , Uveitis/pathology , Uveitis/surgery , Visual Acuity/physiology
16.
Arq. bras. oftalmol ; 68(3): 410-414, maio-jun. 2005. ilus
Article in Portuguese | LILACS | ID: lil-410461

ABSTRACT

A retinopatia diabética continua sendo importante causa de cegueira entre adultos americanos e brasileiros. Existem fatores ambientais determinantes para o desenvolvimento da retinopatia diabética apesar de número crescente de evidências sugerirem um componente genético na retinopatia diabética. Os avanços realizados nas últimas décadas com o objetivo de melhorar o entendimento dos mecanismos envolvidos no desenvolvimento e progressão da retinopatia diabética estimularam esta revisão. Este artigo tem como objetivo revisar e atualizar conceitos acerca da fisiopatologia ocular do diabetes mellitus.


Subject(s)
Humans , Adult , Diabetic Retinopathy , Iris/blood supply , Iris/pathology , Retinal Neovascularization/etiology , Diabetic Retinopathy/pathology , Diabetic Retinopathy/physiopathology
17.
Article in English | IMSEAR | ID: sea-87005

ABSTRACT

Snake venoms are complex heterogenous poisons with multiple effects. Ocular complications with snake bite are rare. This report describes two cases which developed bilateral acute angle closure glaucoma following snake bite. There was complete recovery in the two patients following timely diagnosis and treatment.


Subject(s)
Adult , Animals , Antivenins/therapeutic use , Female , Glaucoma, Angle-Closure/chemically induced , Humans , Iris/pathology , Male , Snake Bites/complications , Snake Venoms/toxicity
18.
Bol. Asoc. Méd. P. R ; 96(2): 77-83, Mar.-Apr. 2004.
Article in English | LILACS | ID: lil-411071

ABSTRACT

BACKGROUND: Uveitis in herpes simplex virus (HSV) ocular disease is usually associated with corneal stromal disease. It has generally been believed that herpetic uveitis in the absence of corneal disease is very rare. When seen it is usually attributed to varicella zoster virus (VZV) infections. The diagnosis of uveitis caused by herpes simplex is often not diagnosed resulting in inadequate treatment and a poor visual result. METHODS: Seven patients from a large uveitis practice who presented with a clinical picture of: anterior uveitis and sectoral iris atrophy without keratitis, a syndrome highly suggestive of herpetic infection, are reported. Polymerase chain reaction (PCR) was done in the aqueous of four of them and was positive for HSV. One patient had bilateral disease. Most of the patients also had severe secondary glaucoma. RESULTS: Of the seven patients presented five had no history of any previous corneal disease. Two had a history of previous dendritic keratitis which was not active at the time of uveitis development. One patient with bilateral disease was immunosuppressed at the time when the uveitis developed. Six of the seven patients had elevated intraocular pressures at the time of uveitis and five required glaucoma surgery. Intractable glaucoma developed in two patients leading to rapid and severe visual loss despite aggressive management. CONCLUSION: Findings suggest that uveitis without corneal involvement may be a more frequent manifestation of ocular herpes simplex disease than previously thought. Absence of corneal involvement delays a correct diagnosis and may worsen visual outcome. Primary herpetic uveitis (when there is no history of previous corneal disease) seems to be more severe than the uveitis in patients with previous corneal recurrences. The associated glaucoma may be a devastating complication


Subject(s)
Male , Adolescent , Middle Aged , Humans , Keratitis, Herpetic/complications , Uveitis, Anterior/virology , Atrophy , Acyclovir/therapeutic use , Antiviral Agents/therapeutic use , Cataract Extraction , Chronic Disease , Cataract/complications , Keratitis, Dendritic/complications , Keratitis, Herpetic/diagnosis , Keratitis, Herpetic/drug therapy , Adrenal Cortex Hormones/therapeutic use , Glaucoma/etiology , Glaucoma/surgery , Aqueous Humor/virology , Iris/pathology , Simplexvirus/isolation & purification , Trifluridine , Uveitis, Anterior/complications , Uveitis, Anterior/diagnosis , Uveitis, Anterior/drug therapy
20.
Rev. mex. oftalmol ; 74(3): 97-108, mayo-jun. 2000. ilus, tab, CD-ROM
Article in Spanish | LILACS | ID: lil-294999

ABSTRACT

Los nevi de la úvea son frecuentes (2 por ciento de la población general), pueden localizarse en el iris, cuerpo ciliar o coroides. Los nevi de más fácil diagnóstico son los del iris, que pueden ser únicos o múltiples y en ocasiones originan alteraciones en el aparato de filtración dando como resultado glaucoma (síndrome del nevo del iris). Los del cuerpo ciliar pasan inadvertidos en la mayoría de los casos. Los localizados en la coroides son lesiones frecuentes y se descubren accidentalmente en la fundoscopia. Los melanomas son la forma maligna, los más frecuentes son los de coroides y les siguen los del cuerpo ciliar e iris. El pronóstico depende de muchos factores y el tratamiento es controversial. Los melanocitomas son lesiones benignas aunque ocasionalmente pueden desarrollar cambios a melanoma. Se les localiza en papila y en cuerpo ciliar. El prognoma melanótico es una lesión muy rara propia de la infancia. La hiperplasia de células névicas (melanosis) puede ser congénita o adquirida, primaria y secundaria, las adquiridas y primarias son las que representan mayor riesgo que representan mayor riesgo de epicarcinogénesis.


Subject(s)
APUD Cells , Iris/pathology , Melanosis , Neural Crest/pathology , Nevus, Pigmented , Uvea/pathology , Choroid/pathology , Melanoma , Precancerous Conditions
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