Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 2.475
Filter
1.
Artrosc. (B. Aires) ; 29(1): 1-7, 2022.
Article in Spanish | LILACS, BINACIS | ID: biblio-1369633

ABSTRACT

La artroplastia total de rodilla (ATR) es un procedimiento altamente exitoso, sin embargo, podemos encontrar pacientes insatisfechos. Aunque la insatisfacción posterior a una ATR es un problema multifactorial, existe un interés creciente en el alineamiento como causa modificable del problema. El alineamiento ideal en ATR aún sigue siendo motivo de controversia y se describen muchas técnicas. La técnica clásica y más utilizada es el alineamiento mecánico, pero existen otros como el anatómico, mecánico ajustado, cinemático, cinemático reverso y el recientemente descripto alineamiento funcional. En esta revisión narrativa se detallan las técnicas de alineamiento más utilizadas, sus beneficios y problemas, y se comentan cuáles podrían ser los nuevos lineamientos que podrían guiar las técnicas de alineamiento en los próximos años


Total knee arthroplasty (TKA) is a highly successful procedure; however, we can find dissatisfied patients. Although post-TKA dissatisfaction is a multifactorial problem, there is growing interest in alignment as a modifiable cause of the problem. The ideal alignment in TKA is still controversial and many techniques are described. The classic and most used technique is mechanical alignment, but there are others such as anatomical, adjusted mechanical, kinematic, reverse kinematic alignment and the recently described functional alignment. This narrative review details the most used alignment techniques, their benefits and problems, and comments on what could be the new guidelines that could guide alignment techniques in the coming years


Subject(s)
Arthroplasty, Replacement, Knee , Knee Joint/surgery
2.
Rev. bras. med. esporte ; 27(3): 249-252, July-Sept. 2021. tab, graf
Article in English | LILACS | ID: biblio-1288588

ABSTRACT

ABSTRACT Introduction High-intensity rehabilitation training will produce exercise fatigue. Objective A backpropagation (BP) network neural algorithm is proposed to predict sports fatigue based on electromyography (EMG) signal images. Methods The principal component analysis algorithm is used to reduce the dimension of EMG signal features. The knee joint angle is estimated by the regularized over-limit learning machine algorithm and the BP neural network algorithm. Results The RMSE value of the regularized over-limit learning machine algorithm is lower than that of the BP neural network algorithm. At the same time, the ρ value of the regularized over-limit learning machine algorithm is closer to 1, indicating its higher accuracy. Conclusions The model training time of the regularized over-limit learning machine algorithm has been greatly reduced, which improves efficiency. Level of evidence II; Therapeutic studies - investigation of treatment results.


RESUMO Introdução O treinamento de reabilitação de alta intensidade produzirá fadiga ao exercício. Objetivo Um algoritmo neural de backpropagation network (BP) é proposto para prever a fadiga esportiva com base em imagens de sinais de eletromiografia (EMG). Métodos O algoritmo de análise de componente principal é usado para reduzir a dimensão das características do sinal EMG. O ângulo da articulação do joelho é estimado usando o algoritmo de aprendizado de máquina de limite regularizado acima e o algoritmo de rede neural BP. Resultados o valor RMSE do algoritmo de aprendizado de máquina acima do limite regularizado é menor que o do algoritmo de rede neural BP. Ao mesmo tempo, o valor de ρ do algoritmo de aprendizado de máquina acima do limite regularizado está próximo de 1, indicando sua maior precisão. Conclusões O tempo de treinamento do modelo de algoritmo de aprendizado de máquina acima do limite regularizado foi bastante reduzido, o que melhora a eficiência. Nível de evidência II; Estudos terapêuticos: investigação dos resultados do tratamento.


RESUMEN Introducción El entrenamiento de rehabilitación de alta intensidad producirá fatiga por ejercicio. Objetivo Se propone un algoritmo neuronal de red de retropropagación (BP) para predecir la fatiga deportiva basándose en imágenes de señales de electromiografía (EMG). Métodos El algoritmo de análisis de componentes principales se utiliza para reducir la dimensión de las características de la señal EMG. El ángulo de la articulación de la rodilla se estima mediante el algoritmo de la máquina de aprendizaje por encima del límite regularizado y el algoritmo de red neuronal BP. Resultados el valor de RMSE del algoritmo de la máquina de aprendizaje por encima del límite regularizado es menor que el del algoritmo de red neuronal de BP. Al mismo tiempo, el valor ρ del algoritmo de la máquina de aprendizaje por encima del límite regularizado está más cerca de 1, lo que indica su mayor precisión. Conclusiones El tiempo de entrenamiento del modelo del algoritmo de la máquina de aprendizaje por encima del límite regularizado se ha reducido en gran medida, lo que mejora la eficiencia. Nivel de evidencia II; Estudios terapéuticos: investigación de los resultados del tratamiento.


Subject(s)
Humans , Principal Component Analysis , Fatigue , High-Intensity Interval Training , Algorithms , Signal Processing, Computer-Assisted , Electromyography , Knee Joint/physiology
3.
Rev. bras. med. esporte ; 27(5): 498-503, July-Sept. 2021. tab, graf
Article in English | LILACS | ID: biblio-1288623

ABSTRACT

ABSTRACT Introduction: As skiers need to complete their movements in high mountains and snow, the athlete's landing's stability is directly related to the movement's success. The stable landing action wins high scores for the athletes' participating actions and protects their safety. Objective: This article analyzes the characteristics of lower limb muscle strength and static balance ability of female freestyle skiing aerials athletes to provide athletes with targeted strength training, evaluation of muscle effects after training, and athlete selection to provide a scientific basis valuable Theoretical reference. Methods: The paper uses isokinetic testing and balance testing methods to study the characteristics of the hip and knee flexor and extensor strengths of the Chinese great female freestyle skiing aerials athletes and the static balance characteristics in four standing positions. Results: The right flexor-extensor force, flexor-extensor force ratio, and average power value of the right hip joint were slightly greater than the left flexor power. The left and right knee joint extensor unit peak weight moments and the left and right average power values were all four indicators. Greater than the flexor, at different test speeds of 60°/s (slow speed) and 240°/s (fast), the peak flexion and extension torque per unit weight, the average power of flexion and extension, the force of flexion and extension, and the average power appear with the increase of the test speed as a significant difference. Conclusions: The research in the thesis recommends reasonable weight control and balanced training of muscle strength, using the condition of moderately increasing exercise speed, to strengthen the training of lower limb extensor strength, provide targeted strength training for athletes, evaluate the muscle effect after training and providing the scientific basis and valuable theoretical reference. Level of evidence II; Therapeutic studies - investigation of treatment results.


RESUMO Introdução: Como os esquiadores precisam completar seus movimentos em altas montanhas e neve, a estabilidade de pouso do atleta está diretamente relacionada ao sucesso do movimento. A ação de pouso constante ganha altas pontuações para os participantes e protege sua segurança. Objetivo: este artigo discute as características da força muscular das extremidades inferiores e habilidade de equilíbrio estático de atletas de esqui estilo livre para fornecer aos atletas treinamento de força específico e avaliação pós-treino dos efeitos musculares em atletas selecionados para fornecer uma base científica de referência teórica valiosa. Métodos: O artigo usa testes isocinéticos e métodos de teste de equilíbrio para estudar as características de força dos flexores e extensores de quadril e joelho de grandes atletas chinesas de esqui estilo livre e as características de equilíbrio estático em quatro posições de pé. Resultados: A força flexor-extensora direita, a relação da força flexor-extensora e o valor médio da potência da articulação do quadril direito foram ligeiramente maiores do que a potência do flexor esquerdo. Os momentos máximos de peso da unidade extensora da articulação do joelho esquerdo e direito e os valores médios das potências esquerda e direita foram os quatro indicadores. Maior que o flexor, em diferentes velocidades de teste de 60 ° / s (velocidade lenta) e 240 ° / s (rápido), o torque máximo de flexão e extensão por unidade de peso, a força média de flexão e extensão, a força de flexão e extensão, e a potência média aparece com o aumento da velocidade de teste como uma diferença significativa. Conclusões: A pesquisa na tese recomenda o controle de peso razoável e o treinamento de força muscular balanceado, utilizando a condição de aumentar moderadamente a velocidade do exercício, para fortalecer o treinamento de força extensora de membros inferiores, fornecer treinamento de força específico para atletas, avaliando o efeito muscular após formar e fornecer a base científica e um valioso referencial teórico. Nível de evidência II; Estudos terapêuticos- investigação dos resultados do tratamento.


RESUMEN Introducción: Como los esquiadores necesitan completar sus movimientos en alta montaña y nieve, la estabilidad del aterrizaje del atleta está directamente relacionada con el éxito del movimiento. La acción de aterrizaje estable gana puntuaciones altas para las participantes y protege su seguridad. Objetivo: Este artículo analiza las características de la fuerza muscular de las extremidades inferiores y la capacidad de equilibrio estático de las atletas de esquí de estilo libre para proporcionar a los atletas un entrenamiento de fuerza específico y una evaluación de los efectos musculares después del entrenamiento en atletas seleccionados para proporcionar una base científica de referencia teórica valiosa. Métodos: El artículo utiliza pruebas isocinéticas y métodos de prueba de equilibrio para estudiar las características de la fuerza de los flexores y extensores de cadera y rodilla de las grandes atletas chinas de esquí de estilo libre femenino y las características del equilibrio estático en cuatro posiciones de pie. Resultados: La fuerza flexora-extensora derecha, la relación de fuerza flexora-extensora y el valor de potencia promedio de la articulación de la cadera derecha fueron ligeramente mayores que la potencia del flexor izquierdo. Los momentos de peso máximo de la unidad extensora de la articulación de la rodilla izquierda y derecha y los valores de potencia promedio izquierda y derecha fueron los cuatro indicadores. Mayor que el flexor, a diferentes velocidades de prueba de 60 ° / s (velocidad lenta) y 240 ° / s (rápido), el par máximo de flexión y extensión por unidad de peso, la potencia promedio de flexión y extensión, la fuerza de flexión y extensión, y la potencia media aparecen con el aumento de la velocidad de prueba como una diferencia significativa. Conclusiones: La investigación en la tesis recomienda un control de peso razonable y un entrenamiento equilibrado de la fuerza muscular, utilizando la condición de aumentar moderadamente la velocidad del ejercicio, para fortalecer el entrenamiento de la fuerza extensora de las extremidades inferiores, proporcionar entrenamiento de fuerza específico para los atletas, evaluar el efecto muscular después del entrenamiento y proporcionar la base científica y una valiosa referencia teórica. Nivel de evidencia II; Estudios terapéuticos- investigación de los resultados del tratamiento.


Subject(s)
Humans , Female , Adult , Young Adult , Skiing/physiology , Postural Balance/physiology , Muscle Strength/physiology , Knee Joint/physiology , Algorithms , Kinetics , Models, Theoretical
4.
Cambios rev. méd ; 20(1): 87-93, 30 junio 2021. ilus.
Article in Spanish | LILACS | ID: biblio-1292972

ABSTRACT

INTRODUCCIÓN. Los defectos de la fosa poplítea suponen un desafío reconstructivo para el cirujano plástico, dada la relación íntima de esta área con la articulación de la rodilla y la neurovasculatura vital subyacente. El propósito de éste informe fie compartir la experiencia en la utilización de un colgajo fasciocutaneode la arteria safena. CASO CLÍNICO. Paciente de 5 años de edad que sufrió quemadura térmica en miembros inferiores con dos años y medio de evolución, ameritó injertos, presentó contractura por tejido cicatricial en fosa poplítea, dificultó la deambulación y desarrollo neuro osteomuscular. Se realizó reconstrucción de la fosa poplítea con colgajo fasciocutáneo de la arteria safena. RESULTADOS. El colgajo fasciocutáneo de la arteria safena dio cobertura al defecto en fosa poplítea izquierda tras retiro del tejido cicatricial que producía contractura, limitaba la marcha y el desarrollo neuro osteo-muscular. Seis meses postquirúrgicos brindó cobertura cutánea definitiva y estable en el área crítica, que permitió la deambulación con movimientos de extensión y flexión de rodilla conservados. DISCUSIÓN. Este colgajo al igual que en otros estudios que respaldan su ejecución brindó excelentes resultados en defectos de partes blandas a nivel de la articulación de la rodilla. CONCLUSIÓN. El colgajo fasciocutáneo de la arteria safena demostró utilidad para la reconstrucción del defecto de la fosa poplítea, posibilitó una cobertura definitiva, funcional y estética, restableció los ángulos de movilidad y favoreció el desarrollo pondoestatural del paciente.


INTRODUCTION. Defects of the popliteal fossa pose a reconstructive challenge for the plastic surgeon, because of the intimate relation of this area with the knee joint and the near vital neurovasculature; the purpose of this report was to share the experience of using a fasciocutaneous flap of the saphenous artery. CLINICAL CASE. A 5 year old patient who suffered thermal burn in lower limbs with two and a half years of evolution, he nedeed grafts and presented tissue contracture because the scar in the popliteal fossa hindered ambulation and neuro-osteomuscular growth. Reconstruction of the popliteal fossa was made it with a fasciocutaneous flap of the saphenous artery. RESULTS. The fasciocutaneous flap of the saphenous artery covered the defect in the left popliteal fossa after removal of the scar tissue that caused contracture, limited to walk and growth. Six months after surgery the flap provided definitive and secure skin coverage in the critical area, which allowed to walk with preserved knee extension and flexion movements. DISCUSSION. This flap was useful for the recons-truction of the defect of the popliteal fossa and provided excellent results in soft tissue defects in this area of the knee joint. CONCLUSION. The fasciocutaneous flap of the saphenous artery proved useful for the reconstruction of the popliteal fossa defect, it permited a definitive, functional and esthetic coverage, reestablished the angles of mobility and helped with the patient growth


Subject(s)
Humans , Male , Child, Preschool , Arteries , Regeneration , Surgical Flaps , Burns , Lower Extremity/injuries , Pediatrics , Child Development , Skin Transplantation , Motor Skills Disorders , Knee , Knee Joint
5.
Rev. Pesqui. Fisioter ; 11(2): 401-410, Maio 2021. ilus, tab
Article in English, Portuguese | LILACS | ID: biblio-1253989

ABSTRACT

OBJETIVOS: A osteoartrite do joelho (OAJ) é a doença crônica das articulações mais prevalente. Existem vários fatores biomecânicos que afetam o alinhamento das articulações do joelho, resultando em deformidades em varo ou valgo, o que leva a cargas desiguais nas estruturas articulares. O objetivo principal do estudo é determinar as correções biomecânicas na tíbia e deformidade em varo na osteoartrite tibiofemoral medial do joelho (MTKJOA). O objetivo secundário é ver a melhora nas funções físicas dos pacientes. METODOLOGIA / DESENHO: Um ensaio clínico randomizado equivalente de dois grupos pré-teste-pós-teste. O total de '52' pacientes será incluído entre a idade de 35 a 80 anos com osteoartrite da articulação tibiofemoral medial. Os sujeitos serão divididos no grupo de correção biomecânica (Técnica de correção manual de deformidade em varo além do tratamento fisioterapêutico convencional). E grupo de fisioterapia convencional, que inclui eletroterapia e terapia por exercícios. Para medir a dor, será realizada a Escala Numérica de Dor (NPRS) para o goniômetro de amplitude de movimento. O Índice de Artrite da Western Ontario McMaster Universities (WOMAC) será utilizado para avaliar o desempenho físico; e o Software TraumaCaD será utilizado para determinar o alinhamento do membro afetado. Em ambos os grupos, o tratamento fisioterapêutico convencional será realizado por 9 dias. No total, 9 sessões serão dadas em três semanas, e em cada semana, 3 sessões serão dadas em dias alternativos. O resultado será medido no início do estudo. REGISTRO DE ENSAIOS: Registro de Ensaios Clínicos - Índia. (NCT04324931). NÚMERO UNIVERSAL DE ENSAIO: U1111-1249-3661. DISCUSSÃO: Até onde sabemos, este estudo será o primeiro a corrigir o eixo biomecânico das articulações do joelho. Após a Correção Biomecânica, a distribuição da descarga de peso será ajustada e a progressão da deformidade poderá ser reduzida, o que ajudará a melhorar as tarefas funcionais e evitar a realização precoce da Artroplastia Total do Joelho (ATJ).


OBJECTIVES: Knee osteoarthritis (KOA) is the most prevalent chronic disease of joints. Various biomechanical factors affect the alignment of the knee joints resulting in the varus or valgus deformities, which leads to unequal loading on the joints structures. The study's primary aim is to determine the biomechanical corrections on tibia and varus deformity in Medial Tibiofemoral Knee Joint Osteoarthritis (MTKJOA). A secondary aim is to see the improvement in the physical functions of the patients. METHODOLOGY/DESIGN: A Two Group Pretest-Posttest Equivalent Randomized Clinical Trial. Total '52' patients will be included between 35 to 80 years with medial tibiofemoral joint osteoarthritis. Subjects will be divided into the biomechanical correction group (Manual varus deformity correction technique in addition to conventional physiotherapy treatment). Conventional physiotherapy group, which includes electrotherapy and exercise therapy. For measuring the pain, the Numeric Pain Rating Scale (NPRS) will be taken, for a range of motion goniometer will be taken, Western Ontario McMaster Universities Arthritis Index (WOMAC) will be taken for assessing the physical performance, and TraumaCaD Software will be used to determine the alignment of the affected limb. In both groups, conventional physiotherapy treatment will be given for nine days. A total of nine sessions will be given in three weeks, and each week, 3 sessions will be given on alternate days. The outcome will be measured at baseline. TRIAL REGISTRATION: Clinical Trials Registry ­ India. (NCT04324931). UNIVERSAL TRIAL NUMBER: U1111-1249-3661. DISCUSSION: To our knowledge, this study will be the first to correct the biomechanical axis of knee joints. After Biomechanical Correction, the weight-bearing distribution will be adjusted, and progression of deformity can be reduced, which will help improve the functional tasks and prevent early Total Knee Arthroplasty (TKA).


Subject(s)
Osteoarthritis , Exercise Therapy , Knee Joint
6.
Rev. bras. ortop ; 56(1): 24-30, Jan.-Feb. 2021. graf
Article in English | LILACS | ID: biblio-1288658

ABSTRACT

Abstract The present research aims to compare the outcomes from the combined reconstruction of the anterior cruciate ligament (ACL) and of the anterolateral ligament (ALL) with the standard isolated ACL reconstruction in patients with chronic ACL injury. To do so, a meta-analysis was carried out to determine whether the combined ACL and ALL reconstruction would lead to a significant improvement in knee function according to the International Knee Documentation Committee (IKDC), the Lysholm test and KT-2000 evaluation scores and lower graft rupture rates in comparison with isolated reconstruction. To identify randomized controlled trials (RCTs) comparing the combined ACL and ALL reconstruction with the isolated ACL reconstruction, papers published between 2010 and 2019 were searched in the MEDLINE, EMBASE, SPORTDiscus, LILACS and Cochrane Central Register of Controlled Trials databases, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. The stability of the knee joint is only marginally improved with the combined reconstruction of ACL and ALL, and both reconstruction techniques show functional results. The main outcomes sought were patient function and graft stability and rupture rates after ACL reconstruction. Out of the 421 studies identified, 6 were included in our meta-analysis. Study quality (internal validity) was assessed using the Cochrane risk-of-bias tool; in general, the studies included presented moderate-quality evidence. The graft rupture rate was higher in patients undergoing isolated ACL reconstruction (relative risk, 0.22; 95% confidence interval, 0.12 to 0.41; p < 0.00001).


Resumo O objetivo da presentepesquisa é comparar, por meio de uma metanálise, os resultados da reconstrução combinada do ligamento cruzado anterior (LCA) e do ligamento anterolateral (LLA), comparado com a reconstrução isolada padrão, em pacientes com lesão crônica do ligamento cruzado anterior. Buscando alcançar o objetivo da pesquisa, foi realizada uma meta-análise para determinar se a combinação da reconstrução combinada LCA e LLA levaria àmelhoria significativa da função do joelho, medida pelos escores de avaliação International Knee Documentation Committee (IKDC), Lysholm, KT-2000 e menor taxa de ruptura do enxerto, em comparação com a reconstrução isolada. Para identificar ensaios clínicos randomizados (ECR) comparando a reconstrução combinada do LCA e LLA com a reconstrução isolada do LCA, foram pesquisados artigos publicados entre 2010 e 2019 nas bases MEDLINE, EMBASE, SPORTDiscus, LILACS e Cochrane Central RegisterofControlledTrials e seguiram os critérios de Itens de Relatórios Preferidos para Revisões Sistemáticas e Metanálises (PRISMA). A estabilidade da articulação do joelho é apenas marginalmente aprimorada com a reconstrução combinada de LCA e LLA, e ambas as técnicas de reconstrução mostram resultados funcionais. Os principais desfechos procurados foram a função do paciente e as taxas de estabilidade e ruptura do enxerto após a reconstrução do LCA. Dos 421 estudos identificados, 6estudos foram incluídos em nossa meta-análise. A qualidade do estudo (validade interna) foi avaliada usando o instrumento Cochrane risco-de-viés; em geral, foi encontrada uma qualidade moderada de evidências dos estudos incluídos. Os pacientes submetidos à reconstrução isolada do LCA mostraram maior taxa de ruptura do enxerto (RR 0,22; índice de confiança [IC]95%: 0,12-0,41; p< 0,00001).


Subject(s)
Rupture , Wounds and Injuries , Anterior Cruciate Ligament , Anterior Cruciate Ligament Injuries , Knee Joint , Ligaments
7.
Article in Chinese | WPRIM | ID: wpr-888328

ABSTRACT

OBJECTIVE@#To study the three-approach and traditional anterior medial technique to establish the femoral tunnel of position, length, and coronal angle and the early efficacy of anterior cruciate ligament reconstruction.@*METHODS@#Through retrospective research, from December 2018 to June 2019, a total of 36 patients diagnosed with simple anterior cruciate ligament tear and undergoing surgery were collected. All patients had a clear history of knee sprains and were divided into two groups. A group of 16 patients, including 11 males and 5 females, with an average age of (30.13±6.54) years and an injury time of 7 to 60 (30.19±15.78) days, three-approach technique was used to drill the femoral tunnel to reconstruct the anterior cruciate ligament. Another group of 20patients, including 15 males and 5 females, with an average age of (30.80±8.60) years, and an injury time of 7 to 60 (27.35±15.50) days, the traditional anterior medial approach was used to drill the femoral tunnel to reconstruct anterior cruciate ligament. CT 3D reconstruction technique was used to evaluate the femoral tunnel and the knee joint function was evaluated by Lysholm score of the knee joint.@*RESULTS@#All patients achieved primary healing after the surgical incision. No femoral tunnel fracture, vascular and nerve damage, difficulty in graft passage during the operation, and venous thrombosis occurred. All 36 patients were followed up on an outpatient basis, with a follow up period of 9 to 15 (12.00±2.83) months. Three-dimensional CT reconstruction was used to evaluate the femoral tunnel of the patients. The position of the femoral tunnel was described using the quartile method as the three-approach group:the lower (27.83±1.97) % of the femoral condyle and the posterior (25.57±3.20) %;the traditional approach group:the lower (28.38±3.21) % of the femoral condyle and the posterior (26.23±3.20) %. Bone tunnel length, three-approach group:(35.20±5.52) mm in total length, (23.20±2.07) mm in thick bone tunnel;traditional approach group:(34.60±4.26) mm in total length, (22.56±2.50) mm in thick bone tunnel. Coronal plane angle, three-approach group:(47.93±5.98) °;traditional approach group:(41.78±6.62) °. Knee joint Lysholm score, three-approach group:48.67±4.18 before surgery;97.00±2.48 at last follow up;traditional approach group:49.75±5.33 before surgery, 97.30±2.68 at last follow up, there were significant differences before and after surgery, no significant statistical difference between two groups.@*CONCLUSION@#The positions of the femoral tunnel drilled by the two methods were within the range of the anatomic stop of the anterior cruciate ligament, and there was no statistical difference. Compared with the traditional anterior medial approach, the coronal plane angle of the femoral tunnel drilled by the three-approach approach is relatively large, and there were no statistical differences in the length of the tunnel, the early postoperative effect of the two surgical methods, and the operation time. But the three approach has a wider and clearer vision. In addition, the knee flexion angle required for drilling the femoral tunnel during surgery is significantly smaller than that of traditional approach technology, which reduces the difficulty of surgery.


Subject(s)
Adult , Anterior Cruciate Ligament/surgery , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Reconstruction , Female , Femur/surgery , Humans , Knee Joint/surgery , Male , Retrospective Studies , Young Adult
8.
Article in Chinese | WPRIM | ID: wpr-888311

ABSTRACT

OBJECTIVE@#In order to observe the clinical effects of sliding osteotomy for patients with severe knee osteoarthritis and varus knee due to complex femoral extra-articular deformity to achieve the medial and lateral soft tissue balancing during total knee arthroplasty.@*METHODS@#From June 2014 to January 2018, a total of 22 patients with severe knee osteoarthritis and complex extra-articular malformation of femurs were treated with total knee arthroplasty. There were 5 males and 17 females in this group, aged 48 to 76 years old, with an average age of (61.3±13.8) years old. All the patients had varus deformities caused by extra-articular deformities of femur. Hip-knee-ankle(HKA) angle was(158.8±9.7) ° before operation, and the average Knee Society Score (KSS) clinical score was 32.6±6.1;KSS function score was 35.8 ±9.6;the average Hospital for Special Surgical (HSS) score was 39.7±4.6;the average range of motion before operation was (80.6±10.7) °. The mechanical alignment method was used in joint replacement. The flexion space was balanced first. The coronal plane vertical sliding osteotomy was performed on the medial femoral condyle for the imbalance of coronal plane. The sliding distance of the osteotomy block was determined by straightening the gap between the inner and outer sides of the space until the space was balanced. After the separated segments were fixed with several screws, the prosthesis was installed as usual.@*RESULTS@#The wounds of all patients healed in the first stage, and no wound complications occurred. All the 22 patients were followed up, and the duration ranged from 18 months to 3 years with an average of (28.2±10.1) months. X-ray showed that the fracture line disappeared for 2 to 5(3.5±1.5) months without nonunion. HKA angle measured at the latest follow up was (178.8±0.7) °, which wassignificantly different from that before operation. The HSS score was 91.3 ±6.0;KSS clinical score 93.7±3.5;KSS functional score 81.2±6.5;and the average range of motion of knee joint was(121.7±11.6) °, which was statistically significant compared with that before operation.@*CONCLUSION@#For severe knee osteoarthritis patients with complex femoral extra-articular deformity, sliding osteotomy is performed. For severe varus deformity, downward sliding the medial femoral condyle is performed. The operation is relatively simple and the damage is small. It is easy to achieve the balance of internal and external soft tissue in flexion extension space. The short-term clinical effect is satisfactory.


Subject(s)
Aged , Arthroplasty, Replacement, Knee , Female , Femur/surgery , Humans , Knee Joint/surgery , Male , Middle Aged , Osteoarthritis, Knee/surgery , Osteotomy , Range of Motion, Articular , Treatment Outcome
9.
Article in Chinese | WPRIM | ID: wpr-888307

ABSTRACT

OBJECTIVE@#To observe the clinical efficacy of Kinesio Taping combined with electroacupuncture in the treatment of patellofemoral disorder in middle-aged and elderly exercise enthusiasts.@*METHODS@#From April 2018 to April 2020, 62 middle-aged and elderly exercisers with patellofemoral disorder were selected and divided into observation group and control group. In the observation group, there were 30 cases:12 males and 18 females, aged from 35 to 66 years old, with an average age of (48.32±6.80) years old. The observation group was treated with Kinesio Taping and electroacupuncture . In the control group, there were 32 cases:12 males and 20 females, aged from 35 to 67 years old, with an averageage of (48.67±8.13) years old. The patients in the control group was treated with knee electroacupuncture. All the patients in both groups were treated once every other day, 3 times a week, for a total of 4 weeks. The VAS pain score and knee Lysholm score before and after treatment were compared between the two groups before and after treatment, and statistical analysis was conducted.@*RESULTS@#In the control group, 2 patients were not satisfied with the curative effect after 2 weeks of treatment and gave up treatment, while the remaining 60 patients completed all the treatments. After 4 weeks of treatment, the VAS and Lyshlom scores of the control group were 2.73±1.46 and 75.63±8.62 respectively;the VAS and Lyshlom scores of the observation group were 2.02±1.85 and 83.31±5.53 respectively;the VAS and Lyshlom scores of the observation group and the control group were better than those before treatment, and the Lyshlom scores of the observation group were better than those of the control group.@*CONCLUSION@#Kinesio Taping combined with electroacupuncture is aimed at patellofemoral disorderof middle-aged and elderly sports enthusiasts. It has little trauma, can relieve pain and has a fast onset speed, which is readily accepted by patients, and promotes the rehabilitation of knee joint function of patients, thus providing a favorable reference for the promotion in clinical application.


Subject(s)
Adult , Aged , Athletic Tape , Electroacupuncture , Female , Humans , Knee Joint , Male , Middle Aged , Patellofemoral Pain Syndrome , Treatment Outcome
10.
Article in Chinese | WPRIM | ID: wpr-888306

ABSTRACT

OBJECTIVE@#To investigate the clinical results of the application of critical rehabilitation pathway in the rehabilitation after total knee arthroplasty.@*METHODS@#From March 2015 to December 2019, 67 patients with total knee arthroplasty (TKA) were included. There were 49 females and 18 males, 42 cases on the left and 25 cases on the right, with an average age of 60 to 81(70.72±5.92) years old. Critical rehabilitation paths included intensive strength and gait rehabilitation exercises. All patients were evaluated before operation and 3, 12 months after operation. The evaluation indexes included stair climbing test (SCT), six minute walk test (6MWT), quadriceps and hamstring strength, range of motion, visual pain scale (VAS), Western Ontario McMasterUniversity Osteoarthritis score(WOMAC).@*RESULTS@#All the patients completed the entire pathway and the assessment. The results of pre-operative, 3 months after surgery and 12 months after surgery were as follows respectively. SCT-up: (16.32±3.58) s, (18.16±2.46) s, (11.00±1.29) s, @*CONCLUSION@#Critical rehabilitation path is safe and effective. The knee function of patients who receive critical rehabilitation path after TKA is significantly improved in the first 12 months after operation.


Subject(s)
Aged , Aged, 80 and over , Arthroplasty, Replacement, Knee , Female , Humans , Knee Joint/surgery , Male , Middle Aged , Osteoarthritis, Knee/surgery , Quadriceps Muscle , Range of Motion, Articular , Recovery of Function
11.
Article in Chinese | WPRIM | ID: wpr-921947

ABSTRACT

Knee osteoarthritis-associated bone marrow edema-like lesions (KOA-BMLs) is a common MRI imaging feature, which is mainly manifested as abnormal bone marrow hyperintensity in subchondral bone on T2 imaging. The formation of KOA-BMLs may be related to the abnormality of lower limb force line and subchondral bone perfusion, and related histopathological studies showed that the remodeling of bone and bone marrow in these damaged areas was abnormally increased. In KOA patients, the size of BMLs can fluctuate or even disappear in a relatively short period of time, and was closely related to pain, subchondral bone cyst formation, and the progression of KOA. However, the current treatment methods for KOA-BMLs are limited, and there is no uniform guideline or expert consensus, mainly includingmedication, physical therapy and surgical treatment. This article reviews the research progress of the disease characteristics and treatment of KOA-BMLs in order to provide guidance for the clinical diagnosis and treatment of KOA-BMLs.


Subject(s)
Bone Marrow/diagnostic imaging , Bone Marrow Diseases/diagnostic imaging , Edema/diagnostic imaging , Humans , Knee Joint , Magnetic Resonance Imaging , Osteoarthritis, Knee/diagnostic imaging
12.
Article in Chinese | WPRIM | ID: wpr-921940

ABSTRACT

OBJECTIVE@#To investigate whether shifting the femoral opening point and setting a personalized femoral valgus angle can improve the lower limb force line of total knee arthroplasty (TKA) patients with external femoral arch.@*METHODS@#From March 2016 to October 2018, 50 patients (55 knees) with osteoarthritis with genu varus deformity combined with external femoral arch for TKA were selected. There were 10 males and 40 females. The age ranged from 63.1 to 80.5 years old, with an average of (67.8±5.8) years old. Forty-five cases were unilateral and 5 cases were bilateral. The osteoarthritis stages of 55 knees were Kellgren-Lawrence grade Ⅲ to Ⅳ; and the course of disease ranged from 2 to 10 years. PreoperativeSpecial Surgery (Hospital for Special Surgery) scores:pain was 15.20±3.52; function was 8.30±2.96;mobility was 10.15±2.85;muscle strength was 4.20±1.95;flexion deformity was 5.50±3.05;stability was 6.15±2.20; total score was 47.93±3.39. The external femoral arch angle ranged from 6.4° to 16.7°, with a mean of (10.63±2.29) °. The tibiofemoral angle ranged from 7.4° to 12.6°, with a mean of (12.04±3.59)°. The anatomical distal femoral angle ranged from 83.10° to 91.20°, with a mean of (84.55± 1.66)°. And the distance from the center of the knee joint to the lower limb line of force ranged from 2.01 to 6.00 cm, with a mean of (3.57±1.12) cm. During the replacement surgery, the femoral opening point and the valgus angle were individually set to obtain a good line of force of the lower limbs.@*RESULTS@#Before the operation, the distance of femoral opening point ranged from 0.24 to 0.74 cm, with a mean of (0.54±0.10) cm. The distance between the internal and external condyles of the femur ranged from 6.86 to 8.12 cm, with a mean of (7.27±0.27) cm. The preoperative valgus correction angle (VCA) ranged from 7.20° to 13.80°, with a mean of (9.38±1.38) °. The post-correction valgus correction angle' (VCA') ranged from 6.10° to 9.50°, with a mean of (7.36±0.82) °. All patients were followed up, and the duration ranged from 3 to 36 months, with an average of (13.5±5.8) months. All patients obtained good knee function after operation. Three months after operation, HSS scores included pain of 25.30±3.05, function of 18.25±2.05, mobility of 16.05±0.75, muscle strength of 6.20±2.10, flexion deformity of 8.80±1.85, stability of 8.20±1.75; and the total score ranged from 90.00 to 93.00, with an average of 91.82±0.98. The total score was higher than that before operation (@*CONCLUSION@#In TKA combined with external femoral arch, good lower limb force line and knee joint function can be obtained by externally shifting the femoral opening point and setting a personalized femoral valgus angle.


Subject(s)
Aged , Aged, 80 and over , Arthroplasty, Replacement, Knee , Female , Femur/surgery , Humans , Knee Joint/surgery , Lower Extremity , Male , Middle Aged , Osteoarthritis, Knee/surgery
13.
Article in Chinese | WPRIM | ID: wpr-921938

ABSTRACT

OBJECTIVE@#To investigate the clinical effect of arthroscopic fixation of tibial avulsion fracture of posterior cruciate ligament with a knot-free anchor and Endobuton titanium plate.@*METHODS@#From October 2019 to October 2020, 12 patients with tibial avulsion fracture of posterior cruciate ligament were treated with the arthroscopic knot-free anchor and Endobuton titanium plate, including 9 males and 3 females. The age ranged from 23 to 58 years old. The time from injury to operation ranged from 2 to 9 days. There were 2 cases of Meyers typeⅡand 10 cases of Meyers type Ⅲ. There were 2 cases of meniscus injury and 1 case of partial injury of medial collateral ligament. The fracture healing and knee range of motion were evaluated after operation, and the clinicalefficacy was evaluated by Lysholm function score.@*RESULTS@#All patients were followed up for 12 months. All patients healed within 6 months, and there were no complications such as incision infection, lower extremity deep venous thrombosis and internal fixation falling off. The knee flexion range of motion recovered from 50°-90° before operation to 115°-130° 6 months after operation, and no patient had straightening disorder. Lysholm functional score recovered from preoperative 29-54 scores to 86-100 scores 12 months after operation.@*CONCLUSION@#Arthroscopic reduction and fixation of tibial avulsion fracture of posterior cruciate ligament with the knot-free anchor and Endobuton titanium plate has less complications, high fracture healing rate, good extension and flexion angle and early function recovery of knee joint.


Subject(s)
Adult , Arthroscopy , Female , Fractures, Avulsion/surgery , Humans , Knee Joint/surgery , Male , Middle Aged , Posterior Cruciate Ligament/surgery , Suture Techniques , Tibial Fractures/surgery , Titanium , Treatment Outcome , Young Adult
14.
Article in Chinese | WPRIM | ID: wpr-921936

ABSTRACT

OBJECTIVE@#To compare the femoral and tibial tunnel positions of anterior cruciate ligament reconstruction using the modified transtibial (MTT) technique and anteromedial (AM) portal technique.@*METHODS@#Between January 2017 and September 2020, 78 patients with anterior cruciate ligament rupture underwent single-bundle reconstruction with the modified transtibial technique in 39 cases (group MTT) and through anteromedial approach in 39 cases (group AM). There were 25 males and 14 females in group MTT, with an average age of (37.0±2.3) years old; 27 males and 12 females in group AM, with an average age of (37.5±2.2) years old. CT scan of the affected knee was conducted one week after the surgery to measure and compare the femoral tunnels positioning (Fx, Fy), tibial tunnels positioning in the frontal plane(Tx1), tibial tunnels positioning in the sagittal plane (Ty1), and tibial tunnels positioning in the axial plane (Tx2, Ty2) in patients undergoing anterior cruciate ligament reconstruction through Mimics software.@*RESULTS@#Three-dimensional CT reconstruction after the surgery showed that the average Fx and Fy were(25.2±2.1)% and (34.9±3.0)% respectively and the Tx1 and Ty1 were (45.5±3.3)% and (44.7± 3.0)% respectively, while the Tx2 and Ty2 were (47.0±3.0)% and (39.9±4.2)% respectively in group MTT. In group AM, the average Fx and Fy were (26.0±2.0)% and (36.1±3.9)% respectively and the Tx1 and Ty1 were (46.5±3.1)% and (45.6± 3.1)% respectively, while the Tx2 and Ty2 were (47.4±2.5)% and (39.6±3.9)% respectively. There were no statistically significant differences in the femoral and tibial tunnels between the two groups (@*CONCLUSION@#Both the MTT and AM technique can achieve good anatomical positioning of the femoral and tibial tunnels, without significant differences in the positioning of the bone tunnels.


Subject(s)
Adult , Anterior Cruciate Ligament/surgery , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Reconstruction , Female , Femur/surgery , Humans , Knee Joint/surgery , Male , Software , Tibia/surgery , Tomography, X-Ray Computed
15.
Article in Chinese | WPRIM | ID: wpr-921934

ABSTRACT

OBJECTIVE@#To explore the influencing factors of the postoperative effect of arthroscopic treatment of symptomatic discoid lateral meniscus (DLM).@*METHODS@#From September 2008 to September 2015, patients with symptomatic DLM treated by arthroscopic surgery were retrospectively analyzed. The knee function was evaluated by Lysholm scoring system. According to the scoring results, it was divided into excellent (≥90 points), good (80 to 89 points), fair (70 to 79 points) and poor (<70 points). Sixteen research factors were collected, namely gender, operation age, body mass index, work intensity, symptom duration, history of knee injury, involved knee side, DLM classification, DLM injury type, DLM injury site, medial meniscus injury, knee cartilage injury site and degree, Kellgren-Lawrence (K-L) classification, operation method, and latest follow-up time. According to the data type, Kruskall-Wallis rank sum test or @*RESULTS@#According to the inclusion and exclusion criteria, 502 patients were included. Lysholm functional grade at the latest follow-up was higher than that before operation (@*CONCLUSION@#Arthroscopy is a safe and effective method for the treatment of symptomatic DLM. The gender, body mass index, work intensity, age of operation, duration of symptoms and degree of knee cartilage injury are independent influencing factors for the postoperative efficacy of symptomatic DLM.


Subject(s)
Arthroscopy , Cartilage Diseases , Female , Humans , Knee Joint/surgery , Menisci, Tibial/surgery , Retrospective Studies , Risk Factors
16.
Article in Chinese | WPRIM | ID: wpr-921932

ABSTRACT

OBJECTIVE@#To observe the curative effect of one-stage reconstruction of anterior cruciate ligament(ACL), posterior cruciate ligament (PCL) and medial collateral ligament (MCL) in patients with KD-Ⅲ-M knee injury, and to compare the operation time, hospitalization cost and curative effect after arthroscopic reconstruction of PCL with LARS artificial ligament and autogenous hamstring tendon, ACL reconstruction with autogenous hamstring tendon and MCL repair combined with limited incision.@*METHODS@#From March 2016 to January 2019, a total of 36 patients met the criteria of this study. Twenty patients in group A were treated with autogenous hamstring tendon reconstruction of ACL and PCL and repair of MCL, including 17 males and 3 females, with an average age of (34.7±9.2) years old. Sixteen patients in group B with LARS artificial ligament reconstruction of PCL, with an autogenous hamstring tendon reconstruction of PCL and MCL repair as before as group B, including 15 males and 1 female, with an average age of (36.8±8.6) years old. The operation time, hospitalization time and total hospitalization cost were compared between the two groups. The preoperative and postoperative functions of the two groups were evaluated by Hospital for Sepcial Surgery (HSS) score and Lysholm score respectively, and the curative effects were compared within and between groups.@*RESULTS@#All the patients in the two groups were followed up for at least 1 year. There were no complications such as infection and poor wound healing in both groups. There was significant difference in operation time between (120.25±9.55) min in group A and (106.63±8.85) min in group B (@*CONCLUSION@#There was no significant difference in the average hospitalization days between the two groups, but the operation time in group A was longerthan that in group B, and the hospitalization cost in group B was higher than that in group A. There was no difference in HSS score and Lysholm score before and follow-up for a certain period of time after operation.


Subject(s)
Adult , Anterior Cruciate Ligament/surgery , Anterior Cruciate Ligament Injuries/surgery , Arthroscopy , Female , Hamstring Tendons/surgery , Humans , Knee Dislocation , Knee Joint/surgery , Male , Middle Aged , Posterior Cruciate Ligament/surgery , Posterior Cruciate Ligament Reconstruction , Treatment Outcome
17.
Article in Chinese | WPRIM | ID: wpr-921931

ABSTRACT

OBJECTIVE@#To investigate and compare the clinical efficacies of remnant-preserving and remnant-non-preserving, remnant-non-preserving remnant segment preserving and remnant root preserving with anterior cruciate ligament reconstruction.@*METHODS@#From March 2014 to December 2017, 204 patients with anterior cruciate ligament (ACL) injuries were treated by single-bundle ACL reconstruction with hamstring tendon autograft. According to the different methods of remnant preservation, the procedures were divided into remnant segment preserving group (A), remnant root preserving group (B), and remnant-non-preserving group (C). There were 37 males and 39 femalesin group A aged from 16 to 43 years old with an average of (28.80±5.41) years old. The time from injury to operation ranged from 2 to 11 weeks with an average of (3.68±1.04) weeks. In group B, there were 39 males and 25 females aged from 18 to 41 years old with an average of (28.42±5.60) years old. The time from injury to operation ranged from 2 to 10 weeks with an average of (3.36±1.68) weeks. In group C, there were 37 males and 27 females aged from 18 to 43 years old with an average of (29.10±6.11) years old. The time from injury to operation ranged from 3 to 11 weeks with an average of (3.54±1.46) weeks. The range of motion (ROM) of the knee was used to assess the range of extension and flextion of the knee at pre-operation and 24 months after operation. Lysholm score and the international knee documentation committee (IKDC) score were used to assess the knee function. The differences among three procedures were judged by comparing among the three groups at 6, 12 and 24 months postoperatively.@*RESULTS@#All incisions got a one stage healing, and no complications, such as vascular injury, nerve damage and articular infect or the like, occurred. All the patients were followed up, and the follow-up duration of group A ranged from 24.00 to 45.96 months with a mean of (35.52±14.40) months;the follow up duration of group B ranged from 27.96 to 48.00 months with a mean of (37.56±10.68) month;and the follow up duration of group C ranged from 24.00 to 66.00 months with a mean of (37.08±13.44) month. There were no significant differences in follow up time among three groups (@*CONCLUSION@#Compared with remnant-non-preserving group, the residual tissue of anterior cruciate ligament is preserved, which is conducive to promote the healing and remodeling of tendon graft and accelerate the recovery of joint function. Proper fixation of residual tissue and restoration of its tension are the key factors affecting the postoperative efficacy.


Subject(s)
Adolescent , Adult , Anterior Cruciate Ligament/surgery , Anterior Cruciate Ligament Injuries/surgery , Anterior Cruciate Ligament Reconstruction , Arthroscopy , Case-Control Studies , Female , Humans , Knee Joint/surgery , Male , Treatment Outcome , Young Adult
18.
Article in Chinese | WPRIM | ID: wpr-921910

ABSTRACT

OBJECTIVE@#To evaluate clinical efficacy of arthroscopic with platelet-rich plasma (PRP) in treating meniscus injury.@*METHODS@#From January 2015 to December 2019, clinical control study on repair meniscus injury by arthroscopic with PRP between arthroscopic were searched by PubMed, Science Direct, Cochrane library, Chinese Journal Full-text Database, Wanfang and VIP database. Literature screening, data extraction and quality evaluation according to inclusion and exclusion criteria. Visual analogue scale(VAS) of knee joint and Lysholm score at 1, 6 and 12 months after opertaion between two groups were compared, and Western Ontario and McMaster University Osteoarthritis Index (WOMAC) at 3, 6 and 12 months after opertaion between twogroups were also compared.@*RESULTS@#Totally 9 literatures and 329 patients with meniscal injuries were screened, include 146 patients treated by arthroscopic with PRP and 183 patients treated by arthroscopic. There were no statistical differences in VAS between two groups at 1, 6 and 12 months after opertaion. There were differences in Lysholm score at 1 and 6 months after operation between two groups [@*CONCLUSION@#Arthroscopic with PRP for repair meniscus injury has short term efficacy of knee function and delay arthritis, while has similar effect in long term clinical efficacy and relieve pain.


Subject(s)
Arthroscopy , Humans , Knee Joint , Meniscus , Osteoarthritis, Knee , Platelet-Rich Plasma , Tibial Meniscus Injuries/surgery , Treatment Outcome
19.
Article in Chinese | WPRIM | ID: wpr-921902

ABSTRACT

OBJECTIVE@#To explore effectiveness and safety of an inside-out, arthroscopic deep medial collateral ligament pie-crusting release in treating posterior horn of medial meniscus (PHMM) tear in tight medial tibiofemoral compartment of knee joint.@*METHODS@#From January 2016 to December 2017, 61 patients (61 knees) were underwent arthroscopic partial meniscectomies for PHMM tear in tight medial tibiofemoral compartment of knee joint, who were divided into valgus group and pie-crusting group according to exposure of PHMM region . There were 28 patients in valgus group, including 12 males and 16 females aged from 27 to 60 years old with an average age of (35.75±7.57) years old;who were performed conventional valgused knee to exporsure PHMM region. There were 33 patients in pie-crusting group, including 15 males and 18 females aged from 26 to 58 years old with an average age of (36.06±7.93) years old;who were treated with inside-out, arthroscopic deep MCL pie crusting release technique with MM-Ⅱ meniscus suture package (Smith & Nephew). Operation time, preoperative and postopertaive Lysholm score of knee joint, injury of MCL between two groups were recorded and compared.@*RESULTS@#All patients were followed up from 12 to 18 months with an average of (15.19±2.22) months. The incisions were healed at stageⅠ. There were no statistical difference in anatomical classification of PHMM between two groups(@*CONCLUSION@#The inside-out, arthroscopic deep MCL pie-crusting release for the treatment of posterior horn of medial meniscus tear in tight medial tibiofemoral could expand working apace, shorten operation time, reduce injury to MCL and obtain good clinical efficacy.


Subject(s)
Adult , Arthroplasty, Replacement, Knee , Arthroscopy , Collateral Ligaments , Female , Humans , Knee Joint/surgery , Male , Menisci, Tibial/surgery , Middle Aged , Treatment Outcome
20.
Article in Chinese | WPRIM | ID: wpr-921900

ABSTRACT

OBJECTIVE@#To explore effect and significance of lateral closed high tibial osteotomy on recovery of activity of knee joint.@*METHODS@#From February to December 2018, 78 patients with knee osteoarthritis who were treated by high tibial osteotomy for the first time were selected as the observation group, including 46 males and 32 females, aged from 55 to 73 years old with an average age of (61.78±6.39) years old, the course of disease ranged from 6 to 24 months with an average of (16.52±4.25) months;according to Kellgren-Lawrence (K-L) grading, 36 patients were gradeⅡand 42 patients were grade Ⅲ. Another 20 healthy people were selected as healthy group, including 13 males and 7 females, aged from 56 to 73 years old with an average of (60.89±7.12) years old. The expression of miR-146 in peripheral blood was compared between observation group and healthy group. At the same time, patients in observation group were followed up for 6 months. The patients whose knee joint function returned to normal or improved significantly during the follow-up period were admitted as the effective group, while the patients whose knee joint function did not improve significantly or tended to aggravate were admitted as the ineffective group. The clinical data and the relative expression of serum miR-146 between effective group and ineffective group were analyzed.@*RESULTS@#The relative expression of serum miR-146 in observation group after operation was significantly higher than that in healthy group (@*CONCLUSION@#The expression level of serum miR-146 showed upward trend, which could regulate the differentiation of chondrocyte. The monitoring of miR-146 after operation has reference value for predicting the recovery of bone and joint function after operation.


Subject(s)
Aged , Female , Humans , Knee Joint , Male , MicroRNAs/genetics , Middle Aged , Osteoarthritis, Knee/surgery , Osteotomy , Tibia/surgery , Treatment Outcome
SELECTION OF CITATIONS
SEARCH DETAIL