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Rev. colomb. cir ; 37(2): 245-250, 20220316. tab, fig
Article in Spanish | LILACS | ID: biblio-1362958


Introducción. Los linfangiomas son anormalidades benignas del sistema linfático, que corresponden a dilataciones quísticas de estos vasos y se localizan especialmente en el cuello. Solo el 10 % de todas estas malformaciones se encuentran en el abdomen y presentan síntomas variables de acuerdo al tamaño y su ubicación especifica, siendo el dolor abdominal el principal síntoma. Métodos. Se presentan cinco pacientes pediátricos con malformaciones linfáticas abdominales. Se describen su cuadro clínico, localización, tratamiento y la experiencia en el manejo de dicha patología en un hospital de referencia. Resultados. Los métodos más apropiados para hacer una aproximación diagnóstica son la ecografía, la tomografía computarizada y la resonancia nuclear magnética. Dentro de las opciones descritas para el tratamiento están la farmacológica, la escleroterapia y la resección quirúrgica, tanto por vía abierta como por laparoscopia. Conclusión. Existe una variedad de métodos para realizar la resección de los linfangiomas abdominales, pero la cirugía sigue siendo la más efectiva, especialmente cuando se cuenta con la laparoscopia como una herramienta terapéutica.

Introduction. Lymphangiomas are benign abnormalities of the lymphatic system, which correspond to cystic dilations of these vessels and are located especially in the neck. Only 10% of all these malformations are found in the abdomen and present variable symptoms according to size and their specific location, with abdominal pain being the main symptom. Methods. Five pediatric patients with abdominal lymphatic malformations are presented. Their clinical presentation, location, treatment and experience in the management of this pathology in a referral hospital are described. Results. The most appropriate methods to make a diagnostic approach are ultrasound, computed tomography and magnetic resonance imaging. Among the options described for treatment are pharmacological, sclerotherapy and surgical resection, both open and laparoscopic. Conclusion. There are a variety of methods for resecting abdominal lymphangiomas, but surgery remains the most effective, especially when laparoscopy is used as a therapeutic tool.

Humans , Lymphangioma , Lymphatic Diseases , Sclerotherapy , Laparoscopy , Lymphatic System
Fisioter. Bras ; 22(2): 272-289, Maio 25, 2021.
Article in Portuguese | LILACS | ID: biblio-1284188


Introdução: O linfedema é a complicação mais frequente no pós-operatório do câncer de mama. Objetivo: Identificar a efetividade do uso da Terapia Complexa Descongestiva (TCD) na redução do volume e no tratamento intensivo do linfedema em pacientes submetidas ao procedimento cirúrgico com esvaziamento axilar devido ao câncer de mama. Métodos: Trata-se de uma revisão sistemática, para o qual foram consultados os bancos de dados Bireme e Pubmed, utilizando artigos científicos em português e inglês de revistas indexadas nas bases de dados Medline, Scielo, Lilacs, Register of Controlled Trials (Cochrane Central) e Physiotherapy Evidence Database (PEDro), publicados entre os anos de 2004 e 2019. Para a construção do trabalho foram incluídos estudos que estivessem disponíveis na íntegra, que a população alvo fosse composta por mulheres submetidas ao procedimento cirúrgico devido ao câncer de mama, com esvaziamento axilar, que apresentassem linfedema e que incluíssem em seus tratamentos, um protocolo fisioterapêutico de TCD. Também de forma independente, foi avaliada a qualidade metodológica dos estudos selecionados com a Escala de Qualidade de JADAD. Resultados: Atualmente, o padrão-ouro dentre as principais técnicas fisioterapêuticas utilizadas para o tratamento do linfedema é a TCD, a qual é composta por drenagem linfática manual, cuidados com a pele e unhas, bandagem de compressão e exercícios terapêuticos. Conclusão: A TCD é considerada o método mais utilizado e eficiente na redução do volume e no tratamento intensivo do linfedema pósmastectomia. (AU)

Introduction: The lymphedema is the most common postoperative complication of breast cancer. Objective: The present study aims to identify the effectiveness of the use of Complex Decongestive Therapy (CDT) in reducing volume and intensive treatment of lymphedema in patients undergoing axillary emptying due to breast cancer. Methods: This was a systematic review, for which Bireme and Pubmed databases were consulted, using scientific articles in Portuguese and English from journals indexed in Medline, Scielo, Lilacs, Register of Controlled Trials (Cochrane Central) databases and Physiotherapy Evidence Database (PEDro), all of them published between the years 2004 to 2019. For the construction of this study, we included articles available in full, with a target population consisting of women undergoing the surgical procedure due to breast cancer, with axillary emptying, who presented lymphedema and who included in their treatments a physical therapy protocol of CDT. Also, independently, the methodological quality of the studies selected was evaluated using the JADAD Quality Scale. Results: Currently, the gold standard among the main physiotherapeutic techniques used for the treatment of lymphedema is CDT, which consists of manual lymphatic drainage, skin and nail care, compression bandaging and therapeutic exercises. Conclusion: The CDT is considered the most used and efficient method for volume reduction and intensive treatment of post-mastectomy lymphedema. (AU)

Humans , Physical Therapy Modalities , Lymphedema , Mastectomy , Breast Neoplasms , Lymph , Lymphatic System
Chinese Journal of Biotechnology ; (12): 2633-2644, 2021.
Article in Chinese | WPRIM | ID: wpr-887829


Endothelial cells that form the inner layers of both blood and lymphatic vessels are important components of the vascular system and are involved in the pathogenesis of vascular and lymphatic diseases. Angiopoietin (Ang)-Tie axis in endothelial cells is the second endothelium-specific ligand-receptor signaling system necessary for embryonic cardiovascular and lymphatic development in addition to the vascular endothelial growth factor receptor pathway. The Ang-Tie axis also maintains vascular homeostasis by regulating postnatal angiogenesis, vessel remodeling, vascular permeability, and inflammation. Therefore, the dysfunction of this system leads to many vascular and lymphatic diseases. In light of the recent advances on the role of the Ang-Tie axis in vascular and lymphatic system-related diseases, this review summarizes the functions of the Ang-Tie axis in inflammation-induced vascular permeability, vascular remodeling, ocular angiogenesis, shear stress response, atherosclerosis, tumor angiogenesis, and metastasis. Moreover, this review summarizes the relevant therapeutic antibodies, recombinant proteins, and small molecular drugs associated with the Ang-Tie axis.

Angiopoietins , Endothelial Cells/metabolism , Humans , Lymphatic Diseases , Lymphatic System/metabolism , Receptor, TIE-2/metabolism , Signal Transduction , Vascular Endothelial Growth Factor A
Article in English | WPRIM | ID: wpr-810984


OBJECTIVE: To evaluate the technical feasibility of intranodal lymphangiography and thoracic duct (TD) access in a canine model.MATERIALS AND METHODS: Five male mongrel dogs were studied. The dog was placed in the supine position, and the most prominent lymph node in the groin was accessed using a 26-gauge spinal needle under ultrasonography (US) guidance. If the cisterna chyli (CC) was not opacified by bilateral lymphangiography, the medial iliac lymph nodes were directly punctured and Lipiodol was injected. After opacification, the CC was directly punctured with a 22-gauge needle. A 0.018-in microguidewire was advanced through the CC and TD. A 4-Fr introducer and dilator were then advanced over the wire. The microguidewire was changed to a 0.035-in guidewire, and this was advanced into the left subclavian vein through the terminal valve of the TD. Retrograde TD access was performed using a snare kit.RESULTS: US-guided lymphangiography (including intranodal injection of Lipiodol [Guerbet]) was successful in all five dogs. However, in three of the five dogs (60%), the medial iliac lymph nodes were not fully opacified due to overt Lipiodol extravasation at the initial injection site. In these dogs, contralateral superficial inguinal intranodal injection was performed. However, two of these three dogs subsequently underwent direct medial iliac lymph node puncture under fluoroscopy guidance to deliver additional Lipiodol into the lymphatic system. Transabdominal CC puncture and cannulation with a 4-Fr introducer was successful in all five dogs. Transvenous retrograde catheterization of the TD (performed using a snare kit) was also successful in all five dogs.CONCLUSION: A canine model may be appropriate for intranodal lymphangiography and TD access. Most lymphatic intervention techniques can be performed in a canine using the same instruments that are employed in a clinical setting.

Animals , Catheterization , Catheters , Dogs , Ethiodized Oil , Fluoroscopy , Groin , Humans , Lymph Nodes , Lymphatic System , Lymphography , Male , Needles , Punctures , SNARE Proteins , Subclavian Vein , Supine Position , Thoracic Duct , Ultrasonography
Gac. méd. boliv ; 42(2): 159-162, dic. 2019. ilus.
Article in Spanish | LILACS | ID: biblio-1293165


El higroma quístico congénito o linfangioma es un tumor del sistema linfático, es de origen embrionario y se origina por la obstrucción del drenaje de los sacos linfáticos. Su localización en orden de frecuencia es en las regiones cervical, axilar, intraperitoneal e inguinal, y muy raro como alteración única en el mediastino anterior. Paciente de 32 años de edad, con embarazo 16 sem ± 6 días y reporte de ecografía: Embarazo de 15 sem ± 20 días, normohidramnia, higroma quístico, Ausencia de hueso nasal además de una comunicación interventricular. Paciente en sala de legrado bajo sedación profunda, se obtiene producto de sexo masculino con alteraciones faciales y aumento de volumen en región cervical. Podemos concluir que, el control prenatal es importante realizar para obtener un diagnóstico precoz con examen ecográfico seriado, estudio genético, ecocardiografía fetal y para dar tratamiento quirúrgico es necesario conformar un equipo multidisciplinario.(AU)

The congenital cystic hygroma or lymphangioma is a tumor of the lymphatic system, is of embryonic origin and is caused by the obstruction of the drainage of the lymphatic sacs. Its location in order of frequency is in the cervical, axillary, intraperitoneal and inguinal regions, and very rare as a single alteration in the anterior mediastinum. A 32-year-old patient with a pregnancy of 16 weeks ± 6 days and an ultrasound report: Pregnancy of 15 weeks ± 20 days, normohydramnia, cystic hygroma, Absence of nasal bone in addition to interventricular communication. Patient in curettage room under deep sedation, male product with facial alterations and volume increase in cervical region is obtained. We can conclude that prenatal control is important to obtain an early diagnosis with serial ultrasound examination, genetic study, fetal echocardiography and to give surgical treatment it is necessary to form a multidisciplinary team.(AU)

Lymphangioma, Cystic , Cleft Lip , Embryonic Development , Lymphatic System
J. vasc. bras ; 18: e20180066, 2019. tab, graf
Article in Portuguese | LILACS | ID: biblio-1002488


O linfedema de membros inferiores é uma doença crônica decorrente de dano no sistema linfático que influencia a mobilidade, a funcionalidade e a qualidade de vida dos indivíduos. Questionários e o teste físico são métodos bastante práticos, de fácil aplicação e baixo custo, que fornecem dados importantes para a avaliação desses pacientes. Objetivos Avaliar a influência do linfedema unilateral de membro inferior na funcionalidade e na qualidade de vida, correlacionando três ferramentas de avaliação. Métodos Estudo descritivo com 25 indivíduos com linfedema unilateral em membro inferior, de ambos os sexos. Foi avaliada a perimetria e foram aplicados The Medical Outcome Study Short Form-36 Health Survey (SF-36) para avaliação da qualidade de vida, Lymphoedema Functioning, Disability and Health Questionnaire for Lower Limb Lymphoedema (Lymph-ICF-LL) para estudo das habilidades físicas, mentais e sociais relacionadas ao linfedema e o Timed Up and Go (TUG) para avaliação da funcionalidade. Resultados Houve a presença de linfedema em todo o membro inferior dos participantes. Os domínios mais prejudicados pelo linfedema foram os aspectos físicos (25,0 ± 31,4) e emocionais (36,0 ± 42,9) no SF-36 e o domínio mobilidade (6,0 ± 2,6) no Lymph-ICF-LL. O TUG foi realizado em 9,88 ± 1,98 s. Houve correlação entre o TUG e os questionários e entre os dois questionários utilizados. Conclusões Indivíduos com linfedema unilateral em membro inferior apresentam um impacto negativo na qualidade de vida e na funcionalidade avaliadas através de questionários, que correlacionam entre si. Não foi encontrada alteração no TUG, mas houve correlação entre ele e os questionários utilizados

Lymphedema of the lower limbs is a chronic disease caused by damage to the lymphatic system that influences people's mobility, functionality, and quality of life. Questionnaires and physical test are very practical, easy to apply, and low cost methods that provide important data for evaluation of these patients. Objectives To evaluate the influence of unilateral lower limb lymphedema on functionality and quality of life, correlating 3 assessment tools. Methods This was a descriptive study investigating 25 patients of both sexes with unilateral lymphedema in a lower limb. Limb volume was assessed using circumferential tape measurements, the Medical Outcomes Study Short Form-36 Health Survey (SF-36) was used to assess quality of life, the Lymphoedema Functioning, Disability and Health Questionnaire for Lower Limb Lymphoedema (Lymph-ICF-LL) was used to assess physical, mental, and social skills related to lymphedema, and the Timed Up and Go (TUG) test was used for functional assessment. Results Lymphedema was present throughout the affected lower limb of participants. The domains most affected by lymphedema were physical aspects (25.0 ± 31.4) and emotional aspects (36.0 ± 42.9) from the SF-36 and the mobility domain (6.0 ± 2.6) from the Lymph -ICF-LL. Patients performed the TUG in 9.88 ± 1.98 seconds. The TUG was correlated with the questionnaires and the questionnaires were correlated with each other. Conclusions People with unilateral lower limb lymphedema exhibited negative impacts on quality of life and functionality, as evaluated by questionnaires, which were correlated with each other. TUG performance was within normal limits, but results correlated with the questionnaires used

Humans , Male , Female , Adult , Middle Aged , Quality of Life , Lower Extremity , Lymphedema/complications , Lymphedema/diagnosis , Comorbidity , Sex Factors , Chronic Disease , Epidemiology, Descriptive , Statistical Analysis , Surveys and Questionnaires , Age Factors , Physical Therapy Specialty/methods , Diabetes Mellitus , Hypertension , Lymphatic System , Obesity
Article in English | WPRIM | ID: wpr-765789


The most important advantages of laparoscopic gastrectomy are the minimal invasiveness, including less postoperative pain, shorter recovery, and minimal complications. A laparoscopic distal gastrectomy is accepted widely as a standard treatment for gastric cancer. On the other hand, a laparoscopic total gastrectomy has not been popularized as a distal gastrectomy because of the complexity of a lymph node dissection and the diversity of reconstruction. In terms of laparoscopic surgery for a remnant gastrectomy, there are three key points, which are critical for safe operation: adequate lymph node dissection, meticulous adhesiolysis, and reconstruction. After radical surgery for gastric cancer, the intra-abdominal condition is greatly changed. In addition, the lymphatic anatomy around the stomach is broken and surgeons should be aware of a newly developed lymphatic system to perform adequate node dissection. An esophago-jejunal reconstruction is at risk of leakage. Until evidence that is more concrete can be obtained, experienced surgeons should consider the laparoscopic approach.

Gastrectomy , Gastric Stump , Hand , Laparoscopy , Lymph Node Excision , Lymphatic System , Pain, Postoperative , Stomach , Stomach Neoplasms , Surgeons
Article in English | WPRIM | ID: wpr-742331


Castleman disease is a relatively rare disease, characterized by well-circumscribed benign lymph-node hyperplasia. The disease may develop anywhere in the lymphatic system, but is most commonly reported as unicentric Castleman disease in the mediastinum along the tracheobronchial tree. It is usually asymptomatic and detected on plain chest radiography as an incidental finding. We report an incidentally detected case of Castleman disease in the paravertebral space that was preoperatively diagnosed as a neurogenic tumor and treated by complete surgical resection.

Castleman Disease , Hyperplasia , Incidental Findings , Lymphatic System , Mediastinal Neoplasms , Mediastinum , Radiography , Rare Diseases , Thorax , Trees
J. vasc. bras ; 17(2): 136-140, abr.jun.2018.
Article in Portuguese | LILACS | ID: biblio-910704


O linfedema é a complicação mais frequente no pós-operatório de câncer de mama, podendo afetar diretamente as atividades diárias. O objetivo desse estudo foi verificar o uso do taping como forma alternativa/auxiliar de tratamento na redução do linfedema. Foi realizada uma revisão da literatura de artigos científicos indexados nas bases de dados PubMed, LILACS, MEDLINE, PEDro e Google Acadêmico, onde foram selecionados nove artigos científicos. Verificou-se que o uso do taping é uma técnica complementar na redução do linfedema, podendo ser uma forma alternativa de tratamento para a redução deste, apesar de não ser capaz de substituir a terapia compressiva multicamadas

Lymphedema is the most common complication during the postoperative period after surgery for breast cancer and can have a direct impact on daily activities. The objective of this study was to review the use of taping as an alternative/complementary treatment to reduce lymphedema. A literature review was conducted of scientific articles indexed on the PubMed, LILACS, MEDLINE, and PEDro databases and Google Scholar, and nine articles were selected. It was found that taping is a complementary therapy for reducing lymphedema, which may be used as an alternative treatment method, but cannot substitute multilayer compression therapy.

Humans , Female , Athletic Tape/ethics , Breast Cancer Lymphedema/rehabilitation , Breast Neoplasms/rehabilitation , Lymphatic System/pathology
Med. interna (Caracas) ; 34(1): 57-60, 2018. ilus
Article in Spanish | LILACS, LIVECS | ID: biblio-1008289


Los linfomas constituyen un grupo diverso de neoplasias malignas, que se originan del sistema linfático(1). Aproximadamente el 85% se agrupan dentro de los denominados Linfomas No Hodgkin (LNH). Los LNH constituyen un numeroso grupo de linfomas derivados de la transformación neoplásica de los linfocitos B, T y Células NK, provenientes de diversas zonas que comprometen los folículos linfáticos en los nódulos linfáticos o en el sistema linfoide extranodal(2). Las localizaciones extra ganglionares primarias representan más de 10% de los casos y los sitios más frecuentes comprenden estómago, intestino delgado, orofaringe, piel, hígado y cerebro; además de otras bastante raras como ano, corazón, músculos y encías. Los linfomas testiculares primarios son muy raros, representan aproximadamente el 5% de todas las neoplasias testiculares malignas, menos del 1% de los LNH y el 4% de los LNH extra nodales(3). Esta neoplasia constituye el tumor maligno testicular más frecuente en sujetos ancianos. La presentación clínica típica es una masa testicular unilateral acompañada en ocasiones de hidrocele y dolor agudo escrotal. A continuación presentamos un caso que requirió de la participación de múltiples especialidades de nuestra institución para un manejo conjunto y finalmente el paciente falleció(AU)

The lymphomas constitute a diverse group of malignant neoplasms, which originate from the lymphatic system(1). Approximately 85% are grouped into the so-called Non-Hodgkin's Lymphomas (NHL). NHL are a large group of lymphomas derived from the neoplastic transformation of B, T and NK cells of different areas with involvement of lymphatic follicles in the lymph nodes or the extranodal lymphoid system(2). The primary extraganglionic sites represent more than 10% of the cases and the most frequent sites include stomach, small intestine, oropharynx, skin, liver and brain; others, quite rare, are anus, heart, muscles and gums.Primary testicular lymphomas are extremely rare, accounting for approximately 5% of all malignant testicular neoplasms, less than 1% of NHL and 4% of extranodal NHL(3). This neoplasm constitutes the most frequent testicular malignant tumor in elderly subjects. The typical clinical presentation is a unilateral testicular mass, sometimes accompanied by hydrocele and acute scrotal pain. We present a case which required the participation of multiple specialties of our institution for management but the patient finally died(AU)

Humans , Male , Middle Aged , Testicular Neoplasms/etiology , Lymphoma, Non-Hodgkin/pathology , Lymphatic System/pathology , Lymphocytes , Internal Medicine , Medical Oncology
Chinese Journal of Traumatology ; (6): 137-151, 2018.
Article in English | WPRIM | ID: wpr-691022


Traumatic brain injury (TBI) remains a major cause of death and disability worldwide. Increasing evidence indicates that TBI is an important risk factor for neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, and chronic traumatic encephalopathy. Despite improved supportive and rehabilitative care of TBI patients, unfortunately, all late phase clinical trials in TBI have yet to yield a safe and effective neuroprotective treatment. The disappointing clinical trials may be attributed to variability in treatment approaches and heterogeneity of the population of TBI patients as well as a race against time to prevent or reduce inexorable cell death. TBI is not just an acute event but a chronic disease. Among many mechanisms involved in secondary injury after TBI, emerging preclinical studies indicate that posttraumatic prolonged and progressive neuroinflammation is associated with neurodegeneration which may be treatable long after the initiating brain injury. This review provides an overview of recent understanding of neuroinflammation in TBI and preclinical cell-based therapies that target neuroinflammation and promote functional recovery after TBI.

Age Factors , Animals , Brain , Allergy and Immunology , Brain Injuries, Traumatic , Therapeutics , Cell- and Tissue-Based Therapy , Methods , Exosomes , Extracellular Vesicles , Physiology , Female , Humans , Inflammation , Lymphatic System , Physiology , Male , Neuroprotective Agents , Sex Characteristics
Article in English | WPRIM | ID: wpr-714546


Chronic lymphedema is caused by an impairment of the lymphatic system due to primary or secondary causes. Vascularized lymph node transplantation (VLNT) is currently the most promising and frequently used technique besides lymphaticovenous anastomosis. However, the vessel anatomy in the lateral thoracic region is sometimes quite variable. Based on our experiences with vascular anatomical inconstancy in the lateral thoracic region, we planned a lateral intercostal artery perforator flap for VLNT in a female patient with chronic stage II lymphedema of both legs after cervical cancer treatment. After surgery, the patient reported significant improvement in limb volume and the accompanying symptoms. The limb circumference was reduced by an average of 19.2% at 6 months postoperatively. Despite having a short pedicle and small vessel caliber, the lateral intercostal artery perforator flap can safely be used for VLNT in lymphedema patients with anatomical variants.

Arteries , Extremities , Female , Free Tissue Flaps , Humans , Leg , Lymph Nodes , Lymphatic System , Lymphedema , Microsurgery , Perforator Flap , Tissue Donors , Transplantation, Autologous , Uterine Cervical Neoplasms
Article in English | WPRIM | ID: wpr-716534


Lymphedema is a common complication associated with cancer itself or with cancer treatment. Lymphedema infrequently occurs after drug therapy. Bee venom is one of the materials used in acupuncture, and it has been used in the treatment of a variety of inflammatory diseases including arthritis. We report a 74-year-old male patient with late-onset post-radiation lymphedema provoked by bee venom therapy. He was free of lymphedema for 5 years after the complete remission of prostate cancer which had been treated with transurethral resection and radiation therapy. The patient developed left leg swelling after undergoing bee venom therapy for left hip pain. Computed tomography and lymphoscintigraphy showed lymphedema without tumor recurrence or infection. The lymphatic system was suspected to be injured by bee venom therapy and lymphedema was provoked. Bee venom therapy should be used cautiously in patients prone to lymphedema.

Acupuncture , Aged , Arthritis , Bee Venoms , Bees , Drug Therapy , Hip , Humans , Leg , Lymphatic System , Lymphedema , Lymphoscintigraphy , Male , Prostatic Neoplasms , Recurrence
Article in English | WPRIM | ID: wpr-739808


Hennekam syndrome is a rare autosomal recessive disorder resulting from malformation of the lymphatic system. The characteristic signs of Hennekam syndrome are lymphangiectasia, lymph edema, facial anomalies, and mental retardation. This is a case in which a patient presented with left-arm lymphedema, facial-feature anomalies, and multiple organ lymphangiectasia consistent with symptoms of Hennekam syndrome. There is no curative therapy at this time, but rehabilitative treatments including complete decongestive therapy for edema control appeared to be beneficial.

Edema , Humans , Intellectual Disability , Lymphatic System , Lymphedema
Article in English | WPRIM | ID: wpr-739546


Small bowel lymphangioma is a rare benign tumor of the lymphatic system, characterized by the presence of dilated lymphatic spaces and significant gastrointestinal bleeding. Small bowel lymphangiomas are rare in adults and case reports are few. Lymphangiomas in the jejunum or ileum are extremely rare and account for less than 1% of all lymphangiomas. The case reported herein is of an older patient (70-year-old male) with melena and chronic anemia (hemoglobin count < 5 g/dL) who had small-sized multiple lymphangiomas in his small bowel (jejunum). Surgical resection was performed after failure of treatment by gastroenteroscopy. Final pathological analysis revealed lymphangioma with thrombus and hemorrhage. After surgery, he no longer had decreased hemoglobin count, nor symptoms of anemia and melena. Also, at the last follow-up visit, the patient's hemoglobin count patient was normal and he returned to normal daily functions.

Adult , Anemia , Endoscopy , Follow-Up Studies , Hemorrhage , Humans , Ileum , Jejunum , Lymphangioma , Lymphatic System , Melena , Thrombosis
Rev. odontopediatr. latinoam ; 8(1): 83-92, 2018. ilus
Article in Spanish | LILACS, COLNAL | ID: biblio-1005967


Los linfangiomas son neoplasias benignas que ocurren predominantemente en la infancia, son muy infrecuentes, y nacen del sistema linfático. Cuando ocurren en la cavidad oral, la localización más común es el dorso de la lengua, seguido por los labios, la mucosa bucal, el paladar blando y el piso de la boca. La prevalencia es de 1 a 3 /10.000 nacidos vivos, afectando ambos generos por igual, involucran en un 75% la cabeza y el cuello, seguido por el tronco, abdomen y extremidades. En esta publicación presentamos una situación de una paciente de sexo femenino de menos de 24 horas de vida que reside en el Servicio de Neonatología H.I.G.A. Pte. Perón en la que se decidió realizar la exéresis de la patología. El objetivo del tratamiento instaurado fué la remoción del tejido exofítico, con margen de seguridad del mismo debido al pequeño tamaño y su base pediculada. Dicho material fué remitido a la Cátedra de Anatomía Patológica de la Facultad de Odontología de la Universidad de Buenos Aires y su diagnóstico histopatológicos, morfológico e inmunohistoquímicos comprobaron la compatibilidad de linfangioma. A los 18 meses de seguimiento post operatorio la paciente no muestra signos evidentes de recidiva o asociados a la patología diagnosticada.

Os Linfangiomas são neoplasias benignas que acontecem geralmente na infância, são muito frequentes, e se originam no sistema linfático. Quando ocorre na cavidade oral, a localização mais comum é no dorso da língua, seguida pelos lábios, mucosa bucal, palato mole e o assoalho da boca. A prevalência é de 1 a 3 /10.000 nascidos vivos, afetando ambos gêneros igualmente. Cerca 75% acometem região de cabeça e pescoço, seguida pelo tronco, abdômen e membros. Nesta publicação, vamos apresentar uma situação de um paciente do sexo feminino de menos de 24 horas de vida proveniente do Serviço de Neonatologia H.I.G.A. Pte. Peron, onde se decidiu fazer a exérese da lesão. O objetivo do tratamento foi a remoção do tecido exofítico, com margem de segurança, devido ao tamanho pequeno e sua base pediculada. O material foi enviado à Cadeira de Anatomia Patológica da Faculdade de Odontologia da Universidade de Buenos Aires e seu diagnóstico histopatológico, morfológico e imunohistoquímico confirmou a compatibilidade com linfangioma. Aos 18 meses de seguimento pós-operatório, o paciente não apresentou sinais evidentes de recidiva ou associados à patologia diagnosticada.

Lymphangiomas are benign neoplasms that appear preferentially in childhood, are very uncommon, and have their origin in the lymphatic system. When they occur in the oral cavity, the most frequent location is the back of the tongue, followed by lips, buccal mucosa, soft palate and floor of the mouth. Prevalence is 1­3/10,000 live births, equally affecting both genders, with 75% involving the head and neck region followed by trunk, abdomen, and extremities. In this publication we present the case of a female patient less than 24 hours of life that remained in the Service of Neonatology Service of H.I.G.A Pte. Perón. According to the clinical evaluation of the Dentistry Service it was decided to perform the excisional biopsy of the pathology. The aim of the treatment was to remove of the exophytic tissue, with safety margin due to the small size and pediculated base. This material was sent to the Chair of Pathological Anatomy of the Odontology Faculty of the University de Buenos Aires and his histopathological, morphological and immunohistochemical diagnosis proved the compatibility of lymphangioma. At the 18 months post-operative follow-up, the patient did not show obvious signs of relapse or othe complications associated with the diagnosed pathology.

Humans , Infant, Newborn , Infant , Infant, Newborn , Lymphangioma , Maxilla , Tongue , Lymphatic System
Med. leg. Costa Rica ; 34(1): 325-231, ene.-mar. 2017. ilus
Article in Spanish | LILACS | ID: biblio-841460


Resumen:Los linfomas son un conjunto de enfermedades neoplásicas que se originan en células del sistema inmunitario, y que afectan específicamente a las células del sistema linfopoyético, que es el encargado de producir los linfocitos. Son considerados como la tercera enfermedad maligna más frecuente de la niñez, representan aproximadamente, el 12% de los casos nuevos de cáncer diagnosticados en los menores de 15 años. De éstos, alrededor de 40% son linfomas de Burkitt.

Abstract:Lymphomas are a set of neoplastic diseases that originate in cells of the immune system and that specifically affect cells lymphopoietic system, which is responsible for producing lymphocytes. They are regarded as the third most common malignant disease of childhood, representing approximately 12% of new cases of cancer diagnosed in children under 15 years. Of these, about 40 % are Burkitt lymphomas.

Humans , Male , Adult , Lymphocytes , Burkitt Lymphoma/diagnosis , Sentinel Lymph Node Biopsy , Forensic Medicine , Lymphatic System , Lymphoma
Fisioter. Bras ; 18(4): f: 505-I: 510, 2017.
Article in Portuguese | LILACS | ID: biblio-907061


O objetivo deste estudo foi verificar os efeitos do Drenagem Linfática Eletrônica (DLE) em edemas de membros inferiores (MMII). A metodologia contou com 2 voluntários do gênero feminino com idade entre 21 e 25 anos, apresentando edemas nos MMII, os quais foram medidos por meio da fita métrica. O aparelho utilizado para realização deste estudo foi o Ciclus®. Foram realizadas as sessões de drenagem linfática eletrônica nos MMII, uma vez por semana, totalizando 10 sessões com duração de 50 minutos cada. Pode-se concluir neste estudo de caso que após a aplicação do aparelho de drenagem linfática eletrônica, houve uma redução significativa nos membros inferiores nos dois participantes do estudo. Porém é necessário realizações de mais estudos práticos com maiores números de participantes e principalmente no que se diz respeito a parâmetros e colocação dos eletrodos. (AU)

The aim of this study was to demonstrate the increase of lymphatic and venous return using electronic lymphatic drainage. The methodology included two female volunteers 20 to 30 years old, with edema of the lower limbs, measured with a metric tape. The equipment used for this study was the Ciclus®. The Electronic lymphatic drainage sessions were performed in the lower limbs once a week, totalling 10 sessions with 50 minutes each. We observed after the application of the electronic lymphatic drainage device a significant reduction in the lower limbs in the two participants. However, it is necessary to carry out more practical studies with larger numbers of participants and especially with regard to parameters and placement of the electrodes. (AU)

Humans , Female , Adult , Electric Stimulation Therapy , Lymphatic System , Edema , Lower Extremity , Therapeutics
Fisioter. Bras ; 18(5): f:624-I:631, 2017.
Article in Portuguese | LILACS | ID: biblio-908576


O edema é uma das disfunções associadas ao sistema linfático caracterizado pelo acúmulo de líquido no espaço intersticial. Para a redução e melhora deste problema existe diversas técnicas que possuem como objetivo estimular o sistema linfático aumentando sua capacidade de absorção e circulação da linfa por entre seus vasos até a corrente sanguínea, de modo manual ou eletrônico, como o caso da drenagem linfática manual e da endermoterapia. O presente estudo teve como objetivo verificar se a endermoterapia como drenagem linfática eletrônica possui os mesmo efeitos que a drenagem linfática manual na redução do edema de membros inferiores. Devido ao seu caráter experimental qualitativo pertinente ao tema escolhido, optou-se por um estudo de caso. Este estudo contou com um voluntário do sexo feminino, com idade de 25 anos, apresentando edema nos membros inferiores. Após avaliação feita por anamnese, perimetria e exame físico, foram realizadas 10 sessões de drenagem linfática manual no membro direito e no membro esquerdo drenagem linfática eletrônica por meio do aparelho de endermoterapia Beauty Dermo Vacuoterapia® da marca HTM, para comparação de ambas as técnicas. As sessões foram realizadas duas vezes na semana em um período de 30 dias. Os resultados obtidos mostraram que houve diminuição de 0,5 cm no membro que recebeu a drenagem linfática manual, enquanto aquele que recebeu a técnica de drenagem linfática eletrônica com aparelho de endermoterapia um total de 5,5 cm, além da melhora no aspecto da pele ocasionado pelos efeitos secundários do aparelho. Com o estudo pode-se concluir que a endermoterapia usada como drenagem linfática eletrônica obteve melhores resultados que a drenagem linfática manual, na redução do edema nos membros inferiores, contudo são necessárias novas pesquisas com um grupo maior de indivíduos para melhores resultados. (AU)

Edema is one of the dysfunctions associated with the lymphatic system characterized by the accumulation of fluid in the interstitial space. To reduce and improve this problem, there are several techniques that aim to stimulate the lymphatic system by increasing its capacity for absorption and circulation of lymph through its vessels into the bloodstream, either manually or electronically, such as manual lymphatic drainage and endermotherapy. This study aimed to verify if the endermotherapy as electronic lymphatic drainage has the same effects as manual lymphatic drainage in the reduction of lower limb edema. This case study had a female volunteer, aged 25 years, presenting edema in the lower limbs. After anamnesis, perimetry and physical examination, 10 sessions of manual lymphatic drainage were performed on the right limb and left lymphatic drainage using the HTM brand Beauty Dermo Vacuoterapia® endermoterapia, for comparison of both techniques. The sessions were held twice a week over a period of 30 days. The results showed that there was a decrease of 0.5 cm in the limb that received manual lymphatic drainage, while the one who received the electronic lymphatic drainage technique with an endermotherapy device, a total of 5.5 cm, besides the improvement in the appearance of the skin caused by the side effects of the appliance. We concluded that the endermotherapy used as electronic lymphatic drainage obtained better results than manual lymphatic drainage, in the reduction of the edema in the lower limbs, however, new studies are necessary with a larger group of individuals for better results. (AU)

Humans , Female , Adult , Lymphatic System , Edema , Lymph , Manual Lymphatic Drainage