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1.
Revista brasileira de ciência e movimento ; 29(1): [1-12], nov. 2021. tab, ilus
Article in Portuguese | LILACS | ID: biblio-1348341

ABSTRACT

Os testes de hipótese são amplamente empregados para análise de dados na área de ciência do esporte. Porém, existe um questionamento em relação a utilização desse método e a comunidade científica ainda procura soluções mais adequadas para a análise dos dados. De fato, esse tipo de análise não permite uma interpretação prática das mudanças observadas ao longo do tempo. Por conta disso, o cálculo da "in ferência baseada em magnitude" (IBM) vem sendo cada vez mais utilizado por pesquisadores e analistas de desempenho. Em uma perspectiva aplicada, a IBM permite avaliar a probabilidade de se encontrar diferenças relevantes (i.e., meaningful differences) nas variáveis investigadas. Da mesma forma, a IBM permite examinar com precisão as variações individuais e importantes no desempenho esportivo. O objetivo desse ponto de vista é apresentar e discutir a aplicação da IBM a partir das análises individuais. Para tanto o trabalho aborda os seguintes temas: 1) utilização da análise de dados no "mundo real"; 2) inferência baseada em magnitude: conceitos básicos; 3) aplicando a IBM no contexto do esporte; 4) classificações qualitativas com base nas mudanças observadas; 5) formas de se obter a mínima mudança válida importante e o erro típico; 6) análise e interpretação dos dados. Esperamos que o conteúdo apresentado encoraje pesquisadores e profissionais do esporte a implementar esse novo método de análise em suas rotinas diárias e, ao mesmo tempo, lhes auxilie na interpretação dos dados provenientes das avaliações e testes de desempenho.(AU)


Null hypothesis tests are widely used for data analysis in sport science. However, the scientific community has been questioning this method and is still looking for alternative approaches for data analyses. In fact, this type of analysis does not allow practical interpretation of the changes observed in athletic performance over time. Therefore, the magnitude-based inference (MBI) method has been increasingly used by researchers and performance analysts. From an applied perspective, this method allows examining the probability of finding meaningful differences in assessed variables. In addition, the MBI enables precise assessment of individual changes, which may be releva nt to sport performance. The aim of this article is to present and discuss the application of the individual MBI analysis. Based on this purpose, the manuscript covers the following topics: 1) utilization of data analysis in real world settings; 2) basic concepts of the MBI; 3) applying the MBI approach in sport science; 4) qualitative classifications based on observed changes; 5) different methods to determine the smallest worthwhile change and the typical error; 6) data analysis and interpretation. We hope that this study will encourage practitioners and r esearchers to implement this novel statistical approach in their daily routines, for analysis and interpretation of data collected during physical performance measurements.(AU)


Subject(s)
Humans , Hypothesis-Testing , Data Interpretation, Statistical , Physical Functional Performance , Data Analysis , Science , Sports , Measurements, Methods and Theories , Athletic Performance , Athletes
2.
Rev. colomb. cir ; 36(4): 647-656, 20210000. tab
Article in Spanish | LILACS | ID: biblio-1291219

ABSTRACT

Introducción. En Colombia el cáncer gástrico representa un problema de salud pública teniendo en cuenta su alta incidencia y sus elevadas tasas de mortalidad. Cerca del 15 % de los pacientes sufren una pérdida significativa de peso, lo que se asocia con un incremento en la morbilidad y mortalidad. Método. Se realizó un estudio de corte transversal, con el objetivo de determinar la presencia de sarcopenia a través de la medición del índice del psoas por tomografía computarizada y su asociación con morbimortalidad postoperatoria temprana en pacientes con cáncer gástrico. Se incluyeron los pacientes con cáncer gástrico admitidos entre el 1° de enero de 2014 y el 31 de agosto de 2019 en el Hospital Militar Central, en Bogotá, D.C., Colombia. Se hizo un análisis descriptivo, un análisis bivariado y un análisis de regresión logística univariado para determinar la asociación de sarcopenia y complicaciones a 30 días. Todos los análisis fueron realizados en R®. Resultados. Se estudiaron 70 pacientes, encontrando una frecuencia de sarcopenia de 54,3 % (n=38), edad media de 69 años (RIC 54 - 74), mayor proporción de hombres 68,6 % (n=48), siendo menor en el grupo de sarcopenia 55,3 % (n=21), índice de psoas de 0,63 mm (RIC 0,55 - 0,7), mortalidad 2,9 % (n=2) y asociación de sarcopenia con desenlaces a 30 días (OR 1,2; IC95% 0,59 - 2,4). Discusión. Se encontraron resultados similares a los informados en la literatura mundial, con una mortalidad inferior al 3 %. En este estudio, la sarcopenia no se asoció con la aparición de complicaciones a 30 días


Introduction. Gastric cancer represents a public health problem in Colombia considering its high incidence and high mortality rates. About 15% of patients suffer a significant weight loss, which is associated with an increase in morbidity and mortality.Method. A cross-sectional study was carried out in order to determine the presence of sarcopenia by measuring the psoas index by computed tomography and its association with early postoperative morbidity and mortality in patients with gastric cancer. Gastric cancer patients admitted between January 1, 2014 and August 31, 2019 at Hospital Militar Central, in Bogotá, D.C., Colombia were included. Descriptive analysis, bivariate analysis, and univariate logistic regression analysis were performed to determine the association of sarcopenia and complications at 30 days. All analyzes were performed in R®.Results. Seventy patients were studied, finding a frequency of sarcopenia of 54.3% (n=38), mean age of 69 years (IQR 54-74), higher proportion of men 68.6% (n=48), being lower in sarcopenia group 55.3% (n=21), psoas index of 0.63 mm (IQR 0.55 - 0.7), mortality 2.9% (n=2) and no association of sarcopenia with outcomes a 30 days (OR 1.2; 95% CI 0.59 - 2.4). Discussion. Similar results were found to those reported in the world literature, with a mortality of less than 3%. In this study, sarcopenia was not associated with the development of complications at 30 days


Subject(s)
Humans , Stomach Neoplasms , Tomography , Mortality , Measurements, Methods and Theories , Psoas Muscles , Index
3.
Rev. habanera cienc. méd ; 20(4): e4245, 2021. tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1289615

ABSTRACT

Introducción: El crecimiento de los tejidos esqueléticos constituye una respuesta secundaria, compensatoria y mecánicamente obligada a cambiar las matrices funcionales. Cuando por alguna razón las matrices funcionales se ven afectadas en su crecimiento, los tejidos esqueléticos responden también con un grado de afectación dependiendo del momento en que esta se produzca. Entonces la mandíbula como parte del viscerocráneo debe presentar esa relación con el hueso hioides de forma directa. Objetivos: Asociar el comportamiento morfológico del hueso hioides con variables morfológicas de la mandíbula y verificar sí la morfología de los huesos pertenecientes a los esqueletos estudiados está determinada por el conjunto de tejidos blandos que los rodea y marcan el ritmo del proceso de remodelación de crecimiento. Material y Métodos: Se realizó la continuación del estudio osteológico en una muestra ósea de 82 esqueletos con mediciones morfométricas del hueso hioides y la mandíbula. Para evaluar la relación de la morfología del hueso hioides con respecto a la mandíbula, se utilizaron matrices de coeficiente de correlación lineal de Pearson en SPSS versión 22 de Window. Resultados: Se corrobora la relación de la morfología del hueso hioides con el crecimiento del viscerocráneo, debido a la correlación positiva y significativa entre varias variables morfológicas del hioides que se obtuvo, -tanto a nivel de su cuerpo como sus astas o cuernos mayores-, con la mandíbula. Conclusiones: Existe una asociación de la morfología del hueso hioides con respecto a la morfología de la mandíbula(AU)


Introduction: The growth of skeletal tissues constitutes a secondary, compensatory and mechanically obliged response to change the functional matrixes. When the growth of functional matrixes is affected for any reason, the skeletal tissues also respond with a degree of affectation depending on the moment in which it occurs. Then the mandible, as part of the viscerocranium, must present that relationship with the hyoid bone directly. Objective: To associate the morphological behavior of the hyoid bone with the morphological variables of the mandible and verify if the morphology of the bones belonging to the skeletons studied is determined by the set of soft tissues that surround them and set the pace of the growth remodeling process. Material and Methods: The continuation of the osteological study was carried out in a bone sample of 82 skulls by performing morphometric measurements of the hyoid bone and the mandible. Pearson's linear correlation coefficient matrices in SPSS Version 22 were used to evaluate the relationship between the morphology of the hyoid bone and the bones of the mandible. Results: The relationship between the morphology of the hyoid bone and the growth of the viscerocranium is corroborated by the positive and significant correlation between several morphological variables of the hyoid bone obtained - both at the level of its body and its greater horns -, and the mandible. Conclusions: These findings corroborate the association between the morphology of the hyoid bone and the growth of the mandible(AU)


Subject(s)
Humans , Skeleton/metabolism , Hyoid Bone/growth & development , Measurements, Methods and Theories , Mandible/growth & development
4.
Rev. habanera cienc. méd ; 20(3): e3947, tab, graf
Article in Spanish | LILACS | ID: biblio-1280430

ABSTRACT

Introducción: El movimiento corporal, obedece y produce actividad del músculo esquelético para lo cual debe existir un equilibrio muscular estático, a partir del cual se genere el desplazamiento de los elementos anatómicos, involucrados en él, ya sea como respuesta a la volición o a la percepción inconsciente al estímulo que lo demande. Objetivo: Asociar el comportamiento morfológico del hioides con ciertas variables morfológicas del viscerocráneo de esqueletos (excepto la mandíbula). Material y Métodos: Se realizó estudio osteológico en una muestra ósea de 82 esqueletos mediante mediciones morfométricas del hueso hioides y huesos del viscerocráneo. Se utilizaron matrices de coeficiente de correlación lineal de Pearson en SPSS 22 para evaluar la relación de la morfología del hioides con respecto a la morfología de los huesos de la cara. Variables morfológicas del viscerocráneo como ancho bicigomático (abc), ancho transversal externo del paladar óseo (pote), ancho sagital externo del paladar óseo (pose) y la altura del tercio medio de la cara (tmed). Resultados: Se obtuvo una gran correlación positiva y significativa de distintas variables morfológicas del hioides, -tanto de su cuerpo como de sus astas o cuernos mayores- con las variables morfológicas del viscerocráneo. Conclusiones: Se corrobora la asociación de la morfología del hueso hioides con el crecimiento de los huesos del viscerocráneo(AU)


Introduction: Body movement obeys and produces activity in the skeletal muscle for which there must be a static muscle equilibrium that produces the movement of the anatomic elements involved in it, either as a result of volition or as the unconscious perception of a stimulus. Objective: To associate the morphological behavior of the hyoid bone with some morphological variables of the viscerocranium of skeletons (except the jaw). Material and Methods: An osteological study was carried out in a bone sample of 82 skulls by performing morphometric measurements of the hyoid bone and the bones of the viscerocranium. Pearson's correlation coefficient and SPSS Version 22 were used to evaluate the relationship between the morphology of the hyoid bone and the facial bones. Morphological variables of the viscerocranium include: bizygomatic width (BW), external transverse width of the hard palate (ETWHP), external sagittal width of the hard palate (ESWHP), and the height of the middle third of the face (MTF). Results: A very strong positive correlation between different morphological variables of the hyoid bone, -both at the level of its antlers or greater horns- and the morphological variables of the viscerocranium was obtained. Conclusions: These findings corroborate the association between the hyoid bone and the growth of facial bones(AU)


Subject(s)
Humans , Muscle, Skeletal , Palate, Hard , Elements , Hyoid Bone , Measurements, Methods and Theories
5.
An. Fac. Cienc. Méd. (Asunción) ; 54(1): 67-76, 20210000.
Article in Spanish | LILACS | ID: biblio-1178627

ABSTRACT

Introducción: La Enfermedades Neuromusculares se caracterizan por la pérdida progresiva de la fuerza muscular, la morbi-mortalidad aumenta con la exageración de la debilidad muscular determinando mayor riesgo de complicaciones respiratorias. Es de suma importancia evaluar e interpretar adecuadamente la función pulmonar y ventilatoria para poder realizar intervenciones que pueda prevenir dichas complicaciones. Objetivos: El objetivo del estudio fue reportar el estado funcional respiratorio de un grupo de pacientes con ENM en control ambulatorio y relacionar estos hallazgos con umbrales clínicamente relevantes de complicaciones respiratorias, reforzando intervenciones basadas en opiniones de expertos. Materiales y métodos: Se realizó un estudio Descriptivo-Observacional de corte transversal, donde fueron evaluados en forma ambulatoria, de marzo del 2017 a agosto del 2018, 30 niños y adolescentes con enfermedades neuromusculares. Resultados: El 46% del total de pacientes presenta capacidad tusígena no funcional con alto riesgo de complicaciones. No obstante, sólo el 10% del total de pacientes fueron aptos para realizar adecuadamente estudios de espirometría. Durante las pruebas espirométricas, sólo el 50% de los pacientes logró mantener 6 segundos la espiración. Conclusión: Si bien la espirometría es la principal prueba de función pulmonar y una alta proporción de pacientes presentó alteraciones en su morfología, su realización en estados avanzados de enfermedad fue poco factible. Para detectar umbrales de complicaciones respiratorias graves, la medición del flujo generado durante la tos resultó mejor. Conclusión: Si bien la espirometría es la principal prueba de función pulmonar y una alta proporción de pacientes presentó alteraciones en su morfología, su realización en estados avanzados de enfermedad fue poco factible. Para detectar umbrales de complicaciones respiratorias graves, la medición del flujo generado durante la tos resultó mejor.


Introduction: Neuromuscular Diseases are characterized by the progressive loss of muscle mass, morbidity and mortality increases with the progress of muscle weakness due to the increased risk of respiratory complications, so it is very important to properly evaluate and interpret the measurements of lung functions and ventilation to be able to carry out a specific treatment that can reduce respiratory complications. Objectives: The purpose of this work is to present the results of the measurements of flows, volumes, respiratory capacities and spirometric patterns in outpatients with neuromuscular diseases and to verify their usefulness to detect vital risks. Materials and methods: A cross-sectional Descriptive-Observational study was carried out, where 30 children and adolescents with neuromuscular diseases were evaluated on an outpatient basis, from March 2017 to August 2018. Results: 46% of all patients presented a non-functional cough with a high risk of complications and only 10% of all patients were eligible for spirometry studies. During the spirometric tests, 50% of the patients managed to maintain expiration for 6 seconds. In 70% of the patients, abnormalities in the Flow-Volume curve could be detected. Conclusion: Although spirometry is the main pulmonary function test, its usefulness and efficacy in neuromuscular diseases depends on the findings of specific alterations in the morphology of the flow-volume curve, which in many cases are not possible to distinguish.


Subject(s)
Spirometry , Cough , Lung , Neuromuscular Diseases , Respiratory Function Tests , Measurements, Methods and Theories , Control
6.
Rev. argent. radiol ; 85(2): 33-40, abr. 2021. tab, graf
Article in Spanish | LILACS, BINACIS | ID: biblio-1288197

ABSTRACT

Resumen Objetivo: Evaluar la diferencia del trazado cefalométrico manual con el digital en radiografías laterales de cráneo. Materiales y métodos: Inicialmente se realizó un piloto para calibrar al investigador principal, en donde se analizaron 10 radiografías pertenecientes a cinco pacientes del Servicio de Radiología del Centro Odontológico de nuestra institución para evaluar la concordancia entre los dos evaluadores y establecer el tamaño de la muestra. Finalmente, se analizaron 78 radiografías cefalométricas de 39 pacientes, en las que se realizó el trazado cefalométrico de Steiner manual y digital. Esas radiografías se analizaron en una escala 1:1 y posteriormente se evaluó la diferencia de las mediciones mediante el análisis univariado, se determinó en mediana e intervalo intercuartil por separado. En el análisis bivariado, se aplicó la prueba de signo de rangos de Wilcoxon y muestras pareadas para determinar la diferencia de las mediciones cefalométricas de Steiner entre el tipo del análisis cefalométrico. El nivel de significancia se fijó en p < 0,05 y confiabilidad al 95%, respectivamente. Resultados: No hubo diferencia significativa en la mayoría de las mediciones hechas de manera manual y digital, siendo el ángulo interincisal la única medición angular en la cual hubo diferencia significativa al obtener un resultado de p = 0,002. Mientras tanto, en las mediciones lineales, la única medición en la que hubo diferencia significativa fue en el segmento incisivo inferior - NB con p = 0,005. Conclusión: No se encuentran diferencias significativas entre el trazado cefalométrico manual y el digital. No obstante, es importante tener en cuenta que la muestra o población evaluada es reducida para definir conclusiones.


Abstract Objective: To evaluate the difference of the manual cephalometric tracing with the digital tracing on lateral cranial radiographs. Materials and Methods: Initially, a pilot study was carried out to calibrate the principal investigator, where 10 radiographs belonging to 5 patients of the Radiology Service of the Dental Center, were analyzed to evaluate the intraclass concordance between the two evaluators. To establish the size of the sample, finally, 78 cephalometric radiographs of 39 patients were analyzed, in which the manual and digital Steiner cephalometric tracing was performed. These radiographs were analyzed on a 1: 1 scale and then the difference of the measurements was evaluated using the univariate analysis, which was determined in the median and interquartile range, separately. In the bivariate analysis, the Wilcoxon rank sign test and paired samples were applied to determine the difference of Steiner's cephalometric measurements between the cephalometric analysis type. The level of significance was set at p < 0.05 and 95% reliability, respectively. Results: There was no significant difference in most of the measurements made manually and digitally. The interincisal angle the only angular measurement in which there was a significant difference when obtaining a result of p = 0.002, while, in the linear measurements, the only measurement in which there was significant difference was in the lower incisor segment - NB with p = 0.005. Conclusion: There is no significant difference between manual and digital cephalometric tracing, nevertheless it is important to keep in mind that the simple or population evaluated is reduced to define conclusions.


Subject(s)
Humans , Adolescent , Adult , Middle Aged , Cephalometry , Radiography, Dental, Digital , Patients , Population , Radiology , Research Personnel , Skull , Measurements, Methods and Theories , Radiography, Dental , Pilot Projects , Organizations , Sample Size , Materials , Incisor , Methods
7.
Rev. bras. ortop ; 56(2): 175-180, Apr.-June 2021. tab, graf
Article in English | LILACS | ID: biblio-1251344

ABSTRACT

Abstract Objective To evaluate knee alignment in the frontal plane and pelvic balance during the step-down test in female and male soccer players. Methods Cross-sectional study carried out with male and female soccer players from under-15 and under-17 teams of a professional club in Southern Brazil. The step-down test was performed, filmed with a video camera, and evaluated according to the angular measurements obtained during movement using the Kinovea software (open source), version 0.8.24. Results The sample consisted of 38 individuals, 19 males and 19 females. Female athletes had a greater varus angle (9.42º ± 1.65º) compared to male athletes (3.91º ± 2.0º; p = 0.04). There was no difference regarding the unilateral pelvic drop between the groups. In addition, the association between the hip-related pelvic drop and the projection angle on the frontal plane of the knee was weak in both genders. Conclusion Even though the pelvic drop was observed in both genders, young female athletes had greater varus knee angles on the step-down test, which require greater attention to minimize the risk of injury.


Resumo Objetivo Avaliar o alinhamento do joelho no plano frontal e o equilíbrio pélvico durante a descida de um degrau comparando atletas de futebol feminino e masculino. Métodos Estudo transversal, realizado com atletas de futebol das categorias sub-15 e sub-17, de ambos os sexos, de um clube profissional do Sul do Brasil. Foi realizado o teste de descida de um degrau, o qual foi filmado por uma câmera de vídeo, e, em sua avaliação, traçaram-se as medidas angulares durante o movimento por meio do software Kinovea (código aberto), versão 0.8.24. Resultados A amostra foi composta por 38 indivíduos, 19 do sexo masculino e 19 do sexo feminino. As atletas do sexo feminino apresentaram maior ângulo em varo (9,42º ± 1,65º) quando comparadas com os atletas masculinos (3,91º ± 2,0º; p = 0,04). Não houve diferença em relação à queda unilateral da pelve (drop pélvico) entre os grupos, e a associação entre o drop pélvico do quadril e o ângulo de projeção no plano frontal do joelho foi fraca em ambos os sexos. Conclusão Apesar de ambos os sexos terem apresentado queda pélvica, as atletas de base do sexo feminino apresentaram maior angulação do joelho em varo no teste de descida do degrau, e necessitam maior atenção para minimizar o risco de lesão.


Subject(s)
Humans , Male , Female , Pelvis , Soccer , Weights and Measures , Measurements, Methods and Theories , Genu Varum , Athletes , Hip , Knee
8.
Rev. cuba. oftalmol ; 34(1): e971, 2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1289521

ABSTRACT

Objetivo: Comparar las mediciones biométricas realizadas con el IOL Master 500 y el Pentacam AXL. Métodos: Se realizó un estudio transversal en 99 ojos de 99 pacientes miopes con criterio de cirugía fotoablativa, atendidos en el período de enero del año 2019 a enero de 2020, en el Servicio de Cirugía Refractiva del Instituto Cubano de Oftalmología "Ramón Pando Ferrer". Las variables estudiadas fueron edad, sexo, equivalente esférico y características biométricas preoperatorias (longitud axial, profundidad de la cámara anterior y queratometrías), así como su relación, aportadas automáticamente por el IOL Master 500 y el Pentacam AXL para evitar los factores dependientes del operador. El análisis estadístico se realizó con la Prueba t para datos pareados, utilizando una significación del 95 por ciento. Una diferencia con un valor de p < 0,05 fue considerado estadísticamente significativo. Resultados: El 60,61 por ciento de los pacientes eran de sexo femenino y el 39,39 por ciento del masculino, con una edad promedio de 25,67 ± 4,30 años. Se analizaron 51 ojos derechos y 48 izquierdos. El equivalente esférico medio fue de -3,30 ± 1,53 dioptrías. No hubo diferencia estadísticamente significativa entre los valores biométricos (longitud axial, profundidad de la cámara anterior y queratometrías) obtenidos con el IOL Master 500, en comparación con los del Pentacam-AXL (p > 0,05). Conclusión: Las mediciones biométricas (longitud axial, profundidad de la cámara anterior y queratometrías) obtenidas con el IOL Master 500 y el Pentacam-AXL son similares(AU)


Objective: Compare biometric measurements taken with IOL Master 500 and Pentacam AXL. Methods: A cross-sectional study was conducted of 99 eyes of 99 myopic patients with indication of photoablative surgery attending the Refractive Surgery Service at Ramón Pando Ferrer Cuban Institute of Ophthalmology from January 2019 to January 2020. The variables analyzed were age, sex, spherical equivalent and preoperative biometric characteristics (axial length, anterior chamber depth and keratometries) and the relationship to one another, automatically supplied by IOL Master 500 and Pentacam AXL to avoid operator-dependent factors. Statistical analysis was based on the paired T-test with a significance level of 95%. A difference with a p-value < 0.05 was considered to be statistically significant. Results: Of the patients studied, 60.61 percent were female and 39.39 percent were male; mean age was 25.67± 4.30 years. A total 51 right eyes and 48 left eyes were analyzed. Mean spherical equivalent was -3.30 ± 1.53 diopters. No statistically significant difference was found between the biometric values (axial length, anterior chamber depth and keratometries) obtained with IOL Master 500 versus Pentacam AXL (p > 0.05). Conclusion: Similar biometric measurements (axial length, anterior chamber depth and keratometries) are obtained with IOL Master 500 and Pentacam AXL(AU)


Subject(s)
Humans , Male , Female , Adult , Measurements, Methods and Theories , Statistical Analysis , Biometry/methods , Refractive Surgical Procedures/methods , Anterior Chamber/diagnostic imaging , Cross-Sectional Studies
9.
Rev. colomb. gastroenterol ; 36(1): 58-64, ene.-mar. 2021. tab, graf
Article in Spanish | LILACS | ID: biblio-1251522

ABSTRACT

Resumen Introducción: la elastografía en tiempo real, 2D-SWE (Supersonic), es una prueba no invasiva que se utiliza para determinar la elasticidad del hígado y, de esa forma, calcular el grado de fibrosis hepática. En Colombia, la prueba se introdujo en 2016 y no existen hasta el momento estudios del comportamiento de la prueba en todos los pacientes hepáticos, solo se han publicado en pacientes sanos y cirróticos. Objetivo: analizar la experiencia de la aplicación de la elastografía en tiempo real, en sujetos atendidos en el centro de enfermedades hepáticas y digestivas de Bogotá, Colombia. Materiales y métodos: estudio descriptivo retrospectivo de una cohorte de sujetos atendidos entre marzo de 2016 y julio de 2017. Se realizó una historia clínica completa y una prueba de elastografía en tiempo real (Supersonic). Resultados: se incluyeron 654 sujetos, con una mediana de edad de 55 años (rango intercuartílico [RIC]: 45-64). La mediana de valores de fibrosis expresada en kilopascales (kPs) fue de 8,3, con un promedio de 5 mediciones. Se observó una diferencia significativa en el grado de fibrosis entre los grupos de edad y en relación con el diagnóstico final, donde se evidenció una mayor fibrosis en el grupo de enfermedades colestásicas (autoinmune, colangitis biliar primaria [CBP] y superposición autoinmune-CBP). La tasa global de fracaso fue menor al 1%. Conclusiones: es la primera descripción del comportamiento de la prueba a nivel nacional. Los valores de rigidez hepática observados en los diferentes estadios demuestran la utilidad de la prueba para la determinación de la fibrosis hepática en pacientes con diferentes patologías.


Abstract Introduction: Real-time two-dimensional shear wave elastography (2D-SWE) (Supersonic Imagine SA), is a non-invasive test used to determine liver elasticity and calculate the degree of liver fibrosis. In Colombia, this test was introduced in 2016 and, to date, no study has tested its behavior in all liver patients, only in healthy and cirrhotic patients. Objective: To analyze the experience of real-time elastography implementation in subjects treated at the Centro de Enfermedades Hepáticas y Digestivas in Bogotá, Colombia. Materials and methods: This is a retrospective descriptive study of a cohort of subjects treated between March 2016 and July 2017. A complete medical report and a real-time elastography (Supersonic) test were performed. Results: 654 subjects were included, with a median age of 55 years (interquartile range [IQR]: 45-64). The median fibrosis values expressed in kilopascals (kPs) were 8.3, with an average of 5 measurements. There was a significant difference in the degree of fibrosis between the age groups and in relation to the final diagnosis, where there was a greater fibrosis in the cholestatic disease group (autoimmune, primary biliary cholangitis [PBC], and overlap). The overall failure rate was less than 1%. Conclusions: This is the first description of this test behavior in the country. Hepatic stiffness values observed in the different stages demonstrate the usefulness of the test to establish the degree of liver fibrosis in patients with multiple diseases.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Fibrosis , Elasticity Imaging Techniques , Liver , Measurements, Methods and Theories , Medical Records , Elasticity , Research Report , Methods
10.
Rev. odontopediatr. latinoam ; 11(1): 219150, 2021. ilus, tab
Article in Spanish | LILACS, COLNAL | ID: biblio-1147636

ABSTRACT

Objetivos: La presente investigación tuvo como objetivo establecer la correlación entre la presencia de maloclusiones a nivel vertical con el índice del paladar y con la altura palatina. Materiales y Métodos: Estudio de tipo transversal. La población de estudio fue conformada por 134 modelos de yeso con dentición mixta, 81 mujeres y 53 hombres, seleccionados por conveniencia y obtenidos desde el 2014 hasta el 2018 del área de clínica de odontopediatría y ortodoncia en la Escuela Nacional de Estudios Superiores Unidad León. La muestra de estudio fue dividida en 3 categorías según la oclusión; mordida abierta (37), mordida profunda (32) y normoclusión (65). Se realizaron mediciones del ancho intermolar y altura del paladar con el uso de un calibrador digital, posteriormente se obtuvo el índice del paladar y se correlacionó con los parámetros expuestos por Korkhaus mediante la prueba estadística de Spearman. Resultados: La prueba estadística de Spearman refleja que no hay correlación entre la magnitud de los valores del índice del paladar propuestos por Korkhaus con la presencia de maloclusiones a nivel vertical. De igual manera las pruebas estadísticas indican que no existe correlación notable entre la altura del paladar y la oclusión en relación vertical. Conclusiones: El resultado obtenido al usar el índice del paladar no fue capaz de corresponder a los parámetros propuestos por Korkhaus como normales, posiblemente al ser usado durante la etapa de la dentición mixta pues durante este periodo suceden cambios constantes relacionados al crecimiento.


Objetivos: Os objetivos a presente investigação buscou valor uma correlação entre a presença de más oclusões em nível vertical com o índice do palato e com a altura palatina. Materiais e Métodos: Estudo do tipo transversal. A população do estudo foi composta por 134 modelos de gesso com dentição mista, 81 mulheres e 53 homens, selecionados por conveniência e obtidos de 2014 a 2018 na área de Odontopediatria e Ortodontia na Escola Nacional de Ensino Superior Unidade de León. A amostra do estudo foi dividida em 3 categorias de acordo com a oclusão; mordida aberta (37), mordida profunda (32) e normoclusão (65). A medida da largura intermolar e da altura do palato foi feita com o uso de um paquímetro digital, o índice de palato foi posteriormente obtido e relacionado aos parâmetros expostos por Korkhaus por meio do teste estatístico de Spearman. Resultados: O teste estatístico de Spearman mostra que não há correlação entre a magnitude dos valores do índice de palato proposta por Korkhaus e a presença de más oclusões verticais. Da mesma forma, os testes estatísticos indicam que não há correlação notável entre a altura do palato e a oclusão na relação vertical. Conclusões: O resultado obtido com o uso do índice de palato não foi capaz de corresponder aos parâmetros propostos por Korkhaus como normais, possivelmente quando usado durante o estágio de dentição mista, porque durante este período há mudanças constantes relacionadas ao crescimento


Purpose: The aim of the present study is to assess the relation between vertical malocclusions with palatal index and palatal height. Materials and Methods: Transversal study. The sample consisted in 134 stone models within mixed dentition, 81 females and 53 males, they were convenience selected and obtained from the pediatric and orthodontic dentistry medical center at the National School for Superior Studies Unit León since 2014 to 2018. The stone models were divided into three categories according to their kind of occlusion: open bite (37), deep bite (32) and normal bite (65). Palatal width and height were measure by using a digital caliper. Subsequently the palatal index was obtained and it was related with the parameters exposed by Korkhaus using the Spearman statistical test. Results: The Spearman statistical test indicated there is no a clearly relationship between palatal index values exposed by Korkhaus with the presence of vertical malocclusions and in the same way there is no a relationship between palatal height and vertical malocclusions.Conclusions: The result obtained by using the palatal index was no able to indicate an agreement with Korkhaus parameters. Probably this disagreement was due to the constant changes that occur during the period of the mixed dentition.


Subject(s)
Humans , Male , Female , Open Bite , Dentition, Mixed , Measurements, Methods and Theories , Dentition , Malocclusion
11.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 13: 538-546, jan.-dez. 2021. ilus
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1178393

ABSTRACT

Objetivo: Analisar as publicações centradas na Pesquisa Convergente Assistencial na atenção ao idoso. Método: revisão sistemática realizada nas bases de dados utilizando a palavra-chave "Pesquisa Convergente Assistencial" e o descritor "idoso", e suas variações em artigos originais. Resultados: Dezenove publicações foram incluídas, estas foram realizadas predominantemente por enfermeiros e publicadas na mesma área. Contemplam principalmente atividades educativas com profissionais e familiares de idosos a fim de instrumentalizar o cuidado, e se apresentam como método efetivo de transformação de práticas. Contudo, poucos estudos adotam todos os itens teórico-metodológicos propostos pela abordagem. Conclusão: O desenvolvimento da Pesquisa Convergente Assistencial na área da saúde do idoso delineia-se em torno das práticas educativas, e requerer maior clareza metodológica quanto a sua realização


Objective: To analyze the publications centered on the convergent care research in the care of the elderly. Method: A systematic review performed in the databases, using the keyword "convergent assistance research" and the Descriptor "elderly", and their variations in original articles. Results: Nineteen publications were included, these were performed predominantly by nurses and published in the same area. They mainly contemplate educational activities with professionals and relatives of the elderly in order to instrumentalize care, and present themselves as an effective method of transforming practices. However, few studies have adopted all the theoretical-methodological items proposed by the approach. Conclusion: The development of the convergent care research in the health area of the elderly is outlined around educational practices, and requires greater methodological clarity regarding its accomplishment


Objetivo: Analizar las publicaciones centradas en la investigación de la atención convergente en el cuidado de las personas mayores. Método: Una revisión sistemática realizada en las bases de datos, utilizando la palabra clave "investigación de asistencia convergente" y el Descriptor "ancianos", y sus variaciones en los artículos originales. Resultados: Se incluyeron diecinueve publicaciones, que fueron realizadas predominantemente por enfermeras y publicadas en la misma área. Contemplan principalmente actividades educativas con profesionales y familiares de ancianos con el fin de instrumentalizar la atención, y se presentan como un método eficaz de transformación de las prácticas. Sin embargo, pocos estudios han adoptado todos los puntos teóricometodológicos propuestos por el enfoque. Conclusión: El desarrollo de la investigación de la atención convergente en el área de salud de las personas mayores se describe en torno a las prácticas educativas, y requiere una mayor claridad metodológica con respecto a su realización


Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Health of the Elderly , Health Education , Healthcare Models , Measurements, Methods and Theories
12.
Article in Spanish | LILACS, BINACIS | ID: biblio-1353997

ABSTRACT

El desarrollo de teléfonos inteligentes ha creado nuevas oportunidades para incorporar la tecnología médica en la práctica clínica diaria. La medición intraoperatoria exacta de los grados necesarios de corrección es un desafío frecuente para el cirujano cuando realiza osteotomías desrotadoras. Por lo general, se utilizan clavijas divergentes colocadas proximal y distal a la osteotomía que, luego de la desrotación, deben quedar paralelas. Sin embargo, la medición de estos grados, en general, se hace por estimación visual, lo que suele ser poco preciso. El objetivo de este estudio es describir un detalle técnico que combina la aplicación de clavijas divergentes con la medición intraoperatoria mediante telefonía móvil para mejorar la precisión de las osteotomías desrotadoras. Nivel de Evidencia: V


Smartphone technology has created new opportunities to incorporate medical technology into daily clinical practice. Accurate intraoperative measurement of the desired derotation angle is a frequent challenge for the surgeon when performing derotational osteotomies. Divergent pins are commonly used proximal and distal to the osteotomy, which after derotation should remain parallel. However, the measurement of the derotation angle is usually performed by visual estimation, which could be unreliable. The aim of this study is to describe a technical detail that combines the application of divergent pins with intraoperative measurement by mobile phone to improve the accuracy of derotational osteotomies. Level of Evidence: V


Subject(s)
Orthopedics , Osteotomy/methods , Measurements, Methods and Theories , Reconstructive Surgical Procedures/methods , Mobile Applications , Smartphone , Intraoperative Period
13.
Pesqui. bras. odontopediatria clín. integr ; 21(supl.1): e0019, 2021. tab, graf
Article in English | LILACS, BBO | ID: biblio-1340343

ABSTRACT

ABSTRACT Objective: To evaluate how the lower arch spontaneously change after upper rapid palatal expansion in a group of patients with transversal skeletal deficit. Material and Methods: Twenty-four patients treated by the same orthodontist with a rapid palatal expander (RPE) bounded on a deciduous molar have been selected. The sample was divided into two groups: no treatment was provided for group one, while group two was treated using a lip bumper or Schwarz appliance. For each patient, dental casts were collected when the RPE was bounded (T0) and at the end of treatment, 9 months ± 3 months later (T1). Each outcome was analyzed, providing descriptive statistics, main effects significance tests and post-hoc analyses with the objective to evaluate the variations between pre-treatment (TO) and post-treatment (T1) of each of them. Results: If the linear measurements are considered, a significant beneficial effect on both arches is observed. However, the upper arch always shows a major increase of all values at T1 with respect to the lower arch. Even though the post-hoc tables indicate that time differences are all statistically significant across considered partitions, the lower arch's increase is more pronounced in group two, where patients were treated in both arches. If the angular measurements are concerned, the increase of lingual crown inclination was found in all patients, independently from the type of treatment in lower arch. Conclusion: All patients show normalization of upper diameters, regardless of whether the lower arch was treated or not.


Subject(s)
Humans , Male , Female , Orthodontics , Palatal Expansion Technique/instrumentation , Extraoral Traction Appliances , Orthodontists , Malocclusion, Angle Class III , Measurements, Methods and Theories , Prospective Studies , Statistics, Nonparametric , Italy
14.
Braz. J. Pharm. Sci. (Online) ; 57: e181084, 2021. tab, graf
Article in English | LILACS | ID: biblio-1350225

ABSTRACT

Some antioxidant compounds have a pro-oxidant effect in the presence of transition metal ions, due to the reduction of Mn+ to M(n-1)+ with simultaneous formation of free radicals, which then promote DNA damage. In the present study, we evaluated the pUC19 DNA damage in a solution containing Cu(II) and ascorbic acid (AA) or S(IV) saturated with air by agarose gel electrophoresis. Our results showed that this damage decreases if AA and S(IV) are simultaneously added. This study also illustrates the importance of Cu(II) in this process, as no DNA damage was observed when AA or S(IV) were present in the absence of this metallic ion. Our data showed that DNA preservation depends on the concentration of AA and S(IV) and occurs when the [S(IV)]:[AA] ratio ranges from 1:1 to 20:1. Absorbance measurements and thermodynamic data show that no reaction occurs between AA and S(IV) when this mixture (pH 5.5) is added to pUC-19 DNA. The presence of dissolved oxygen may be the cause of AA consumption in the mixture of these two antioxidants, which subsequently decreases DNA damage.


Subject(s)
Ascorbic Acid/adverse effects , Sulfites , DNA Damage , Copper/pharmacology , Ions/adverse effects , Antioxidants/adverse effects , Measurements, Methods and Theories , Electrophoresis, Agar Gel/instrumentation , Free Radicals/pharmacology , Hydrogen-Ion Concentration
15.
Braz. J. Pharm. Sci. (Online) ; 57: e19073, 2021. tab, graf
Article in English | LILACS | ID: biblio-1345463

ABSTRACT

A reversed-phase high performance liquid chromatography (RP-HPLC) method with ultraviolet detection was developed and validated for the simultaneous quantification of antiretroviral drugs lamivudine (3TC), stavudine (d4T), and zidovudine (AZT) in perfusate samples obtained from the Single-Pass Intestinal Perfusion studies. The chromatographic analysis was performed using a Gemini C18 column and didanosine as internal standard (IS). The following parameters were considered for the validation procedure: system suitability, accuracy, precision, linearity and selectivity. The limits of detection were 0.32 µg/mL for 3TC, 0.11 µg/mL for d4T and 0.45 µg/mL for AZT and the limits of quantification were 1.06 µg/mL for 3TC, 0.38 µg/mL for d4T and 1.51 µg/mL for AZT. Repeatability and intermediate precision ranged from 1.05 to 1.31 and 1.50 to 1.87, respectively, and are expressed as percent of relative standard deviation (RSD). Based on these results, the developed and validated RP-HPLC method can be used for simultaneous determination of 3TC, d4T, and AZT in perfusate samples. Furthermore, this method is simple and adequate for measurements of the antiretroviral drugs in the same sample, since those compounds are mostly co-administered. Besides, this work can be used as an initial base for the development of similar methods in the same conditions presented in our study.


Subject(s)
Zidovudine/pharmacology , Chromatography, High Pressure Liquid/methods , Lamivudine/pharmacology , Validation Study , Anti-Retroviral Agents/pharmacology , Perfusion/instrumentation , Permeability , Measurements, Methods and Theories , Pharmaceutical Preparations/administration & dosage , Limit of Detection
16.
Arch. latinoam. nutr ; 70(4): 263-268, dic. 2020. tab, graf
Article in English | LILACS, LIVECS | ID: biblio-1247666

ABSTRACT

Mango is the second most commercialized tropical fruit in the world, and Mexico is the major exporter. In terms of mango production, Manila´s variety represents a quarter of the total mangoes production in Mexico. However, the changes that occur on the phenolic compounds during the Manila mango ripening process are unknown. Quantitative analysis of the major phenolic compounds was conducted at different maturity stages, using several spectrophotometric measurements and by high-performance liquid chromatography (HPLC). At the late ripening stage was observed the biggest content in pulp and peel of total phenols (577 and 10547 mg EAG /100 g), flavonoids (95.33 and 537 mg EQ/100 g), and antioxidant capacity by DPPH (25 and 347 mmol TE/100 g). Some bioactive compounds achieve their highest values at optimal consumption ripening. Although they diminish when the fruit reaches a senescence appearance. This is the first study to prove that mangiferin by itself shows a higher correlation in antioxidant capacity compared to other phenolic compounds in mango peel, and this suggest that phenolic compounds may have an important role in the postharvest antioxidant metabolism in Manila mango fruit. On the other hand, the results show that the peel compared to the pulp contains higher amounts of total phenols, flavonoids, gallic acid, mangiferin and antioxidant capacity, so its use as an ingredient in the preparation of functional food products is recommended. More studies are needed to go in-depth in the changes of the content of phytochemicals during the ripening process in the peel and pulp mango, which ones could be caused by the hormones responsible for ripening in the fruit, such as ethylene, and bioavailability of these compounds at different stages of maturation(AU)


El mango es la segunda fruta tropical más comercializada del mundo y México es el principal exportador. En términos de producción de mango, la variedad Manila representa una cuarta parte de la producción total de mangos en México. Sin embargo, se desconocen los cambios que ocurren en los compuestos fenólicos durante el proceso de maduración del mango Manila. El análisis cuantitativo de los principales compuestos fenólicos se realizó en diferentes etapas de madurez, utilizando varias medidas espectrofotométricas y mediante cromatografía líquida de alta resolución (HPLC). En la etapa de madurez tardía se observó el mayor contenido en pulpa y cáscara de fenoles totales (577 y 10547 mg EAG / 100 g), flavonoides (95.33 y 537 mg EQ / 100 g) y capacidad antioxidante por DPPH (25 y 347 mmol TE / 100 g). Algunos compuestos bioactivos alcanzan sus valores más altos en el punto de madurez óptima. Aunque disminuyen cuando el fruto adquiere una apariencia de senescencia. Este es el primer estudio que demuestra que la mangiferina por sí misma presenta una alta correlación con la capacidad antioxidante en comparación con otros compuestos fenólicos de la cáscara de mango, y esto sugiere que los compuestos fenólicos pueden tener un papel importante en el metabolismo antioxidante postcosecha en el mango Manila. Por otro lado, los resultados muestran que la cáscara comparada con la pulpa contiene mayores cantidades de fenoles totales, flavonoides, ácido gálico, mangiferin y capacidad antioxidante por DPPH, por lo que se recomienda su uso como ingrediente en la elaboración de productos alimenticios fucionales. Se necesitan más estudios para profundizar en los cambios del contenido de fitoquímicos durante el proceso de maduración en la cáscara y pulpa del mango, los cuáles podrían ser provocados por las hormonas responsables de la maduración en el fruto, como el etileno, y la biodisponibilidad de estos compuestos en diferentes etapas de maduración(AU)


Subject(s)
Mangifera , Polyphenols/analysis , Antioxidants , Measurements, Methods and Theories , Phytochemicals , Fruit
17.
Rev. colomb. cardiol ; 27(5): 388-393, sep.-oct. 2020. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1289247

ABSTRACT

Resumen Introducción: El ángulo QRS-T espacial es la diferencia entre el vector del QRS y la T. Se conoce el valor diagnóstico y pronóstico de este marcador en enfermedades cardíacas. Es prioritario determinar si estas mediciones son reproducibles con confiabilidad en nuestro medio. Métodos: En 30 adultos se obtuvieron electrocardiogramas, independientemente del diagnóstico. Las mediciones las realizaron dos estudiantes de Medicina de quinto año, un médico interno y un cardiólogo, posterior a un reentrenamiento sobre la medición del ángulo por el método de transformación visual. Con identificación cegada, ingresaron en un aplicativo web las mediciones del QRS y la T. El ángulo fue estimado a partir de la plantilla de Cortez y colaboradores. Sobre el 20% de las lecturas se estimó un acuerdo intraobservador y en el 100% de las lecturas un acuerdo interobservador. Los puntos de corte para estimar el acuerdo Kappa fueron < 105s (normal), 105° a 135° (limítrofe) y > 135° (anormal). Resultados: Se excluyó un ECG por calidad deficiente. El rango del ángulo estuvo entre 72.9° y 176.2°. El acuerdo interobservador entre los 4 evaluadores fue kappa = 0.786 (IC95% 0.728-0.823, p < 0.0001) y el intraobservador kappa = 1.0 (p 0.007). Conclusión: Es el primer estudio sobre el ángulo QRS-T espacial realizado en Colombia. Se logró un acuerdo inter- e intraobservador adecuado en la medición del ángulo por el método de transformación visual, en observadores con diferente experticia, con un kappa mayor de 0,75. Este resultado apoya la reproducibilidad de esta medición en estudios posteriores en Colombia.


Abstract Introduction: The spatial QRS-T angle is the difference between the QRS vector and T vector. The diagnostic and prognostic value of this marker in heart disease is well-known. It is essential to determine whether these measurements are reproducible and reliable in Colombia. Methods: Electrocardiograms (ECG) were obtained from 30 adults, regardless of the diagnosis. The measurements were made by two fifth-year medical students, a houseman/ intern, and a cardiologist. They were all re-trained on the measurement of the angle using the visual transformation method. With blinded identification, they entered the QRS and T measurements into a web application. The angle was estimated from the template of Cortez et al. About 20% of the readers showed an intra-observer agreement and an inter-observer agreement in 100%. The cut-off points to estimate the agreement Kappa were < 105° (normal), 105° a 135° (borderline), and >135° (abnormal). Results: One ECG was excluded due to poor quality. The range of the angle was between 72.9° and 176.2°. The inter-observer agreement between the 4 evaluators gave a kappa = 0.786 (95% CI; 0.728-0.823, P < .0001), and the intra-observer agreement a kappa = 1.0 (P = .007). Conclusion: This the first study on the spatial QRS-T angle performed in Colombia. A good inter- and intra-observer agreement was achieved in the measurement of the angle by the visual transformation method by observers with different levels of expertise, with a Kappa greater than 0.75. These results support the reproducibility of this measurement in subsequent studies in Colombia.


Subject(s)
Humans , Adult , Measurements, Methods and Theories , Reproducibility of Results , Vectorcardiography , Electrocardiography
18.
Rev. cuba. invest. bioméd ; 39(3): e611, jul.-set. 2020. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1138933

ABSTRACT

Introducción: El organismo se adapta al lugar donde reside, pero este tema no ha sido estudiado en la población laboral peruana. Objetivo: Determinar las variaciones fisiológicas y antropométricas en trabajadores según su residencia en tres altitudes geográficas del Perú. Métodos: Se realizó una investigación transversal analítica, con los datos fisiológicos (6 parámetros de laboratorio) y antropométricos (peso y talla) de 7500 trabajadores en 3 altitudes diferentes: Lima (nivel del mar), Arequipa (2500 m sobre el nivel del mar) y Cerro de Pasco (4300 m sobre el nivel del mar). Estas mediciones fueron estándares, realizadas por clínicas ocupacionales con certificaciones de calidad. Se obtuvo los coeficientes y valores p para las diferencias según cada altitud y ajustados por el sexo y la edad de cada participante. Resultados: Todos los parámetros fisio-antropométricos variaron según la altitud de residencia (todos los valores p fueron menores a 0,005). Los que se incrementaron a mayor altitud fueron la hemoglobina, el colesterol total y el colesterol HDL; en cambio, disminuyeron a mayor altitud el peso y la glucosa en ayunas. En los hombres aumentaron todas las variables menos en el colesterol HDL (que disminuyó significativamente) y el colesterol LDL (que no tuvo variación estadística), en comparación con las mujeres. Conclusiones: Son evidentes las variaciones en las mediciones de los trabajadores según el lugar donde residían, lo que muestra que no se debe tomar parámetros fijos para su valoración laboral. Esto debe servir a los médicos del trabajo y las autoridades, para tener en cuenta al momento de la valoración de la aptitud médica y luego para la vigilancia ocupacional(AU)


Introduction: The human body adapts to its place of residence, but this topic has not been studied in the Peruvian working population. Objective: Determine physiological and anthropometric variations in workers due to their residence in three geographic altitudes in Peru. Methods: An analytical cross-sectional study was conducted of physiological data (6 laboratory parameters) and anthropometric data (weight and height) of 7 500 workers from three different altitudes: Lima (sea level), Arequipa (2 500 m above sea level) and Cerro de Pasco (4 300 m above sea level). The measures were standard and taken by occupational clinics with quality certifications. Coefficients and p values for differences between the altitudes were obtained and adjusted according to the sex and age of participants. Results: All the physio-anthropometric parameters varied with the altitude of the place of residence (all p values were under 0.005). The parameters which increased at a higher altitude were hemoglobin, total cholesterol and HDL cholesterol, whereas the ones which decreased at a higher altitude were weight and fasting glucose. Among men all variables increased except for HDL cholesterol (which decreased significantly) and LDL cholesterol (which did not show any statistical variation), in comparison with women. Conclusions: Variations in measurements taken from workers from different places of residence are obvious, which shows that fixed parameters should not be used for their labor assessment. This should be taken into account by occupational doctors and authorities for medical attitude assessment and occupational surveillance(AU)


Subject(s)
Humans , Male , Female , Body Weights and Measures/adverse effects , Altitude , Altitude Sickness/epidemiology , Laboratories/standards , Occupational Groups , Peru , Measurements, Methods and Theories , Cross-Sectional Studies
19.
Rev. colomb. cardiol ; 27(4): 250-261, jul.-ago. 2020. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1289223

ABSTRACT

Resumen Introducción: la fragilidad es una condición del paciente anciano, caracterizada por un estado de vulnerabilidad para desenlaces adversos en salud, incluidos los causados por la cirugía cardíaca. Objetivo: establecer la prevalencia de fragilidad en el contexto prequirúrgico del anciano sometido a cirugía cardiaca y establecer el riesgo de desenlaces adversos otorgado por esta condición. Metodología: estudio analítico de cohorte que valoró la fragilidad en 66 pacientes ancianos sometidos a cirugía cardiaca mediante el fenotipo físico de fragilidad de Fried. Se realizó un seguimiento a 30 días, durante el cual se estableció la prevalencia de fragilidad y el riesgo otorgado por esta condición a los desenlaces adversos de la cirugía cardiaca. Resultados: la edad de los pacientes osciló entre los 60 y los 83 años; la mediana fue de 70,5 años. La prevalencia de la fragilidad fue del 31,8%. La fragilidad incrementó los siguientes desenlaces adversos postoperatorios: muerte (p 0,001), ventilación prolongada (p 0,001), uso prolongado de vasoactivos (p 0,001) e infección del sitio operatorio (p 0,004). El riesgo de mortalidad otorgado por la fragilidad fue más alto que el de los puntajes usuales de valoración como el EuroSCORE II (HR 5,49; IC95% 1,0-28,5 vs. HR 1,17 IC95% 1,0-1,29). Conclusión: la fragilidad es una condición frecuente en el paciente anciano sometido a cirugía cardiaca e incrementa el riesgo de eventos adversos, en especial el de mortalidad. Se recomienda incluir la medición de la fragilidad en el protocolo prequirúgico del paciente anciano.


Abstract Introduction: Frailty is a common condition in the elderly patient, and is noted for its vulnerability for adverse outcomes in health, including those caused by cardiac surgery. Objective: To establish the prevalence of frailty in the pre-surgical context of the elderly subjected to cardiac surgery, as well as to establish the risk of adverse outcomes due to this condition. Method: An analytical cohort study was performed in order to evaluate frailty in 66 elderly patients subjected to cardiac surgery, using the physical phenotype of frailty described by Fried. A follow-up was made at 30 days, during which the frailty prevalence was established, as well the risk of adverse outcomes of the cardiac surgery due to this condition. Results: The age of the patients varied between 60 and 83 years, with a median of 70.5 years. The prevalence of frailty was 31.8%. Frailty increased the following post-surgical adverse outcomes: death (P = .001), longer ventilation time (P = .001), prolonged use of vasoactive drugs (P = .001), and infection of the surgical site (P = .004). The mortality risk due to frailty was higher than that of the usual evaluation scores such as Euro SCORE II (HR 5.49; 95% CI; 1.0-28.5 vs. HR 1.17: 95% CI; 1.0-1.29). Conclusion: Frailty is a common condition in the elderly patient subjected to cardiac surgery, and increases the risk of adverse events, particularly, mortality. It is recommended to use measurements of frailty in the pre-surgical protocol of the elderly patient.


Subject(s)
Humans , Male , Female , Aged , Thoracic Surgery , Aged , Frailty , Measurements, Methods and Theories , Pharmaceutical Preparations , Cohort Studies
20.
Rev. chil. nutr ; 47(4): 620-629, ago. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1138597

ABSTRACT

RESUMEN Introducción: La determinación del nivel de actividad física (AF) puede realizarse a través de acelerómetro o mediante cuestionario de auto-reporte. El objetivo de este estudio fue comparar los niveles de AF entre un cuestionario de auto-reporte y la medición con acelerómetro de movimiento según factores sociodemográficos en la población chilena. Métodos: Estudio de corte transversal que incluyó a 230 adultos chilenos participantes del proyecto Genes, Ambiente, Diabetes y Obesidad (GENADIO). Niveles de AF fueron medidos mediante el cuestionario Internacional Physical Activity Questionnaire (IPAQ) y acelerómetro de movimiento (ActiGraph). Resultados: IPAQ subestimó los niveles de AF total en comparación a la medición con acelerómetro (delta [IPAQ-Acel.]= −55,7 min/día). Según nivel educacional, se evidenció que el cuestionario IPAQ sobreestimó los niveles de AF total en personas con bajo nivel educacional (delta [IPAQ-Acel.]= 70,4 min/día), pero subestimó la AF total en personas con enseñanza media o técnico universitaria (delta [IPAQ-Acel.]= −67,9 y −135,6 min/día, respectivamente). Resultados similares fueron observados para los distintos niveles de ingreso socioeconómico (NSE). Conclusión: El cuestionario de auto-reporte IPAQ subestimó los niveles de AF total en comparación a la medición por acelerómetro; sin embargo, estas diferencias variaron según factores sociodemográficos.


ABSTRACT Introduction: Determining level of physical activitY (PA) can be done with objective measurement, through accelerometer, or by subjective measurement through self-report questionnaire. The aim of this study was to compare PA measurements derived from a self-reported questionnaire and accelerometer according to sociodemographic factors in the Chilean population. Methods: This was a cross-sectional study which included 230 Chilean adults participating in the GENADIO study (Genes, Environment, Diabetes and Obesity). PA levels were measured through the International Physical Activity Questionnaire (IPAQ) and GT1M accelerometer (ActiTrainer, ActiGraph). Results: IPAQ questionnaire underestimated the total PA levels compared to the accelerometer measurement (delta[IPAQ-Acel.]= −55.7 min/day). According to educational level, IPAQ questionnaire overestimated PA level in people with low educational level (delta[IPAQ-Accel.]= 70.4 min/day), but underestimated total PA in people with secondary education or university technician (delta[IPAQ-Accel.]=-67.9 and-135.6 min/day, respectively). Similar results were observed for the different levels of socioeconomic income. Conclusion: The IPAQ questionnaire underestimated total PA levels compared to accelerometer; however, these differences varied according to sociodemographic factors.


Subject(s)
Adult , Measurements, Methods and Theories , Exercise , Obesity , Population , Chronic Disease , Education, Primary and Secondary , Environment , Genes
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