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Rev. Soc. Peru. Med. Interna ; 33(1): 51-51, ene.-mar. 2020. ilus
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1116254


Un varón de 51 años de edad con antecedentes de tuberculosis (TB) pulmonar en el año 2000, tratado por régimen 2RHZE/4RH. Presentó una recurrencia de TB con baciloscopía positiva y sensible a la rifampicina (Figura 1). Recibió etambutol (15 mg/kg/día), isoniacida (300 mg/día), rifampicina (600 mg/día) y pirazinamida (25mg/Kg/ día), más piridoxina 150 mg/ día. Tres meses después, el paciente presentó pérdida de la agudeza visual (AV) en ambos ojos (AO): 1/10 ojo derecho y 2/10 ojo izquierdo.

Humans , Male , Middle Aged , Optic Nerve Diseases/therapy , Ethambutol/adverse effects , Medical Illustration
Int. braz. j. urol ; 46(1): 108-115, Jan.-Feb. 2020. tab, graf
Article in English | LILACS | ID: biblio-1056353


ABSTRACT Objective: Cystectomy with urinary diversion is the gold standard for muscle invasive bladder cancer. It also may be performed as part of pelvic exenteration for non-urologic malignancy, neurogenic bladder dysfunction, and chronic conditions that result in a non-functional bladder (e.g., interstitial cystitis, radiation cystitis). Our objective is to describe the surgical technique of urinary diversion using large intestine as a conduit whilst creating an end colostomy, thereby avoiding a primary bowel anastomosis and to show its applicability with respect to urologic conditions. Materials and Methods: We retrospectively reviewed five cases from a single institution that utilized the described method of urinary diversion with large intestine. We describe operative times, hospital length of stay (LOS), and describe post-operative complications. Results: Five patients with a variety of urologic and oncologic pathology underwent the described procedures. Their operative times ranged from 5 hours to 11 hours and one patient experienced a Clavien III complication. Conclusion: We describe five patients who underwent this procedure for various medical indications, and describe their outcomes, and believe dual diversion of urinary and gastrointestinal systems with colon as a urinary conduit to be an excellent surgical option for the appropriate surgical candidate.

Humans , Male , Adult , Colon, Sigmoid/surgery , Colostomy/methods , Urinary Diversion/methods , Urinary Bladder Diseases/surgery , Anastomosis, Surgical , Cystectomy/methods , Reproducibility of Results , Treatment Outcome , Operative Time , Length of Stay , Medical Illustration , Middle Aged
J. appl. oral sci ; 28: e20190435, 2020. tab, graf
Article in English | LILACS, BBO | ID: biblio-1056593


Abstract Objective To quantify the bone volume that can be safely withdrawn from 3 donor sites: (1) the mandibular symphysis, (2) the oblique mandibular line and (3) the skullcap. Methodology For the symphysis, 200 tomographic exams were evaluated by the extension of the anterior loop of mental foramen, by the nerve, by the distance of the foramens, by the distance between the vestibular cortical and the lingual plates and by the distance between the apexes, or lower anterior teeth, and the mandibular base, using the "distance" tool of the I-CAT Vision, in the panoramic and parasagittal reformations. For the oblique line, 70 TCFC exams were analyzed retrospectively in panoramic and parasagittal reformations, evaluating the thickness of the vestibular cortical and the distance between the cortical and the mandibular canal. For the cranial bone, a hexagonal donor site located in parietal area was considered. Results The average dimensions of the bone blocks that can be safely removed from the region of the mandibular symphysis are: 32.27 mm in length, 4.87 mm in height and 4 mm in thickness, providing a volume of 628.61 mm3 available for grafting. In the oblique line, the available bone volume for grafting was 859.61 mm3. In the region of the cranial vault, multiplying the average bone thickness by the area of the hexagon, an average volume of 2,499 mm3 was obtained. Conclusions Comparing the donor sites, the bone availability in the cranial vault is 3 times greater than in the mandibular posterior region, and at least 2 times greater than in the mandibular symphysis.

Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Skull/transplantation , Bone Transplantation/methods , Cone-Beam Computed Tomography/methods , Transplant Donor Site , Mandible/transplantation , Skull/diagnostic imaging , Retrospective Studies , Anatomic Landmarks , Transplant Donor Site/diagnostic imaging , Cortical Bone/transplantation , Cortical Bone/diagnostic imaging , Mandible/diagnostic imaging , Medical Illustration
Int. braz. j. urol ; 45(6): 1238-1248, Nov.-Dec. 2019. tab, graf
Article in English | LILACS | ID: biblio-1056340


ABSTRACT Introduction: Pubic hypertrophy, defined as an abnormal and abundant round mass of fatty tissue located over the pubic symphysis, is frequently underestimated in patients with hypospadias. We examined the prevalence of this condition, as well as the outcomes associated with its surgical treatment. Material and methods: Within 266 hypospadias patients treated at our clinic, we assessed the prevalence of pubic hypertrophy, and we schematically described the surgical steps of pubic lipectomy. Multivariable logistic regression (MLR) tested for predictors of pubic hypertrophy. Finally, separate MLRs tested for predictors of fistula and any complications after pubic lipectomy. Results: Of 266 hypospadias patients, 100 (37.6%) presented pubic hypertrophy and underwent pubic lipectomy. Patients with pubic hypertrophy more frequently had proximal hypospadias (44 vs. 7.8%), disorders of sex development (DSD) (10 vs. 0.6%), cryptorchidism (12 vs. 2.4%), and moderate (30°-60°) or severe (>60°) penile curvature (33 vs. 4.2%). In MLR, the location of urethral meatus (proximal, Odds ratio [OR]: 10.1, p<0.001) was the only significant predictor of pubic hypertrophy. Finally, pubic lipectomy was not associated with increased risk of fistula (OR: 1.12, p=0.7) or any complications (OR: 1.37, 95% CI: 0.64-2.88, p=0.4) after multivariable adjustment. Conclusions: One out of three hypospadias patients, referred to our center, presented pubic hypertrophy and received pubic lipectomy. This rate was higher in patients with proximal hypospadias suggesting a correlation between pubic hypertrophy and severity of hypospadias. Noteworthy, pubic lipectomy was not associated with increased risk of fistula or any complications.

Humans , Adolescent , Adult , Young Adult , Lipectomy/methods , Hypospadias/surgery , Hypospadias/epidemiology , Penis/surgery , Postoperative Complications , Pubic Bone/surgery , Logistic Models , Prevalence , Retrospective Studies , Risk Factors , Treatment Outcome , Statistics, Nonparametric , Serbia/epidemiology , Hypertrophy/surgery , Hypertrophy/epidemiology , Medical Illustration
Rev. bras. cir. cardiovasc ; 34(5): 618-623, Sept.-Oct. 2019. tab, graf
Article in English | LILACS | ID: biblio-1042033


Abstract In aortic valve disease cases, prosthetic valves have been used for valve replacement, however, these prostheses have inherent problems, and their quality in some countries is lower comparing to new-generation models, causing shorter durability. Aortic valve neocuspidization (AVNeo) has emerged as an option, which can be applied to a wide spectrum of these diseases. Despite the promising results, this procedure is not widely spread among cardiac surgeons yet. We developed a surgical technique combining Bentall and Ozaki procedures to treat patients with concomitant ascending aorta replacement and AVNeo and we describe it in this paper.

Humans , Aorta/surgery , Aortic Valve/surgery , Prosthesis Design/standards , Heart Valve Prosthesis/standards , Heart Valve Prosthesis Implantation/methods , Heart Valve Diseases/surgery , Reproducibility of Results , Medical Illustration
Arq. neuropsiquiatr ; 77(9): 646-653, Sept. 2019. tab, graf
Article in English | LILACS | ID: biblio-1038742


ABSTRACT The sciatic nerve forms from the roots of the lumbosacral plexus and emerges from the pelvis passing inferiorly to the piriformis muscle, towards the lower limb where it divides into common tibial and fibular nerves. Anatomical variations related to the area where the nerve divides, as well as its path, seem to be factors related to piriformis syndrome. Objective: To analyze the anatomical variations of the sciatic nerve and its clinical implications. Methods: This was a systematic review of articles indexed in the PubMed, LILACS, SciELO, SpringerLink, ScienceDirect and Latindex databases from August to September 2018. Original articles covering variations of the sciatic nerve were included. The level of the sciatic nerve division and its path in relation to the piriformis muscle was considered for this study. The collection was performed by two independent reviewers. Results: At the end of the search, 12 articles were selected, characterized according to the sample, method of evaluation of the anatomical structure and the main results. The most prevalent anatomical variation was that the common fibular nerve passed through the piriformis muscle fibers (33.3%). Three studies (25%) also observed anatomical variations not classified in the literature and, in three (25%) the presence of a double piriformis muscle was found. Conclusion: The results of this review showed the most prevalent variations of the sciatic nerve and point to a possible association of this condition with piriformis syndrome. Therefore, these variations should be considered during the semiology of disorders involving parts of the lower limbs.

RESUMO O nervo isquiático forma-se a partir das raízes do plexo lombosacro e emerge da pelve passando inferiormente ao músculo piriforme, em direção ao membro inferior onde se divide em nervos tibial e fibular comum. Variações anatômicas relativas ao local onde ocorre a divisão desse nervo, bem como do seu trajeto, parecem ser fatores relacionados à síndrome do piriforme. Objetivo: Analisar as variações anatômicas do nervo isquiático e suas implicações clínicas. Materiais e Métodos: Trata-se de uma revisão sistemática de artigos indexados nas bases de dados PubMed, LILACS, SciELO, SPRINGERLINK, SCIENC DIRECT e LATINDEX. Foram incluídos artigos originais envolvendo as variações do nervo isquiático. Considerou-se para este estudo o nível de divisão do nervo isquiático e o seu trajeto em relação ao músculo piriforme. A coleta foi realizada por dois revisores independentes. Resultados: Ao final da busca foram selecionados 12 artigos, caracterizados quanto à amostra, método para avaliar a estrutura anatômica e principais resultados. A variação anatômica mais prevalente foi aquela em que o nervo fibular comum atravessa as fibras do músculo piriforme (33,3%). Três estudos (25%) observaram, ainda, variações anatômicas não classificadas na literatura e em outros três (25%) constatou-se a presença de um músculo piriforme duplo. Conclusão: Os resultados desta revisão mostram as variações mais prevalentes do nervo isquiático e apontam para uma possível associação dessa condição com a síndrome do piriforme. Desse modo, essas variações devem ser consideradas durante a semiologia dos distúrbios envolvendo os membros inferiores.

Humans , Male , Female , Sciatic Nerve/anatomy & histology , Piriformis Muscle Syndrome/pathology , Piriformis Muscle Syndrome/etiology , Anatomic Variation , Medical Illustration
Int. braz. j. urol ; 45(3): 560-571, May-June 2019. tab, graf
Article in English | LILACS | ID: biblio-1012321


ABSTRACT Purpose: To introduce our experience with intracorporeal ileal conduit and evaluate the safety and feasibility of this endoscopic urinary diversion. Materials and Methods: Between March 2014 and July 2017, thirty-six consecutive patients underwent laparoscopic radical cystectomy with intracorporeal ileal conduit. Patients' demographic data, perioperative data, 90-days postoperative outcomes and complications were collected. This cohort were divided into two groups of 18 patients each by chronological order of the operations to facilitate comparison of clinical data. Data were evaluated using the students' T test, Mann-Whitney test and Fisher's Exact test. Results: All surgeries were completed successfully with no conversion. Median total operating time and median intracorporeal urinary diversion time were 304 and 105 minutes, respectively. Median estimated blood loss was 200 mL, and median lymph node yield was 21. Twenty-six Clavien grade < 3 complications occurred within 30-days and 9 occurred within 30-90 days. Five Clavien grade 3-5 complications occurred within 30 days. No statistically significant differences were found between the two groups except for intracorporeal urinary diversion time. At median follow-up of 17.5 (range 3-42) months, 6 patients experienced tumor recurrence/metastasis and 4 of these patients died. Conclusions: Intracorporeal ileal conduit following laparoscopic radical cystectomy is safe, feasible and reproducible. With the accumulation of experience, the operation time can be controlled at a satisfactory level.

Humans , Male , Female , Adult , Aged , Urinary Diversion/methods , Urinary Bladder Neoplasms/surgery , Adenocarcinoma/surgery , Cystectomy/methods , Laparoscopy/methods , Postoperative Complications , Time Factors , Urinary Bladder Neoplasms/pathology , Anastomosis, Surgical , Carcinoma, Squamous Cell/surgery , Carcinoma, Squamous Cell/pathology , Adenocarcinoma/pathology , Prospective Studies , Reproducibility of Results , Treatment Outcome , Statistics, Nonparametric , Surgical Stomas , Neoplasm Grading , Operative Time , Medical Illustration , Middle Aged , Neoplasm Staging
Rev. bras. cir. cardiovasc ; 34(2): 187-193, Mar.-Apr. 2019. tab, graf
Article in English | LILACS | ID: biblio-990579


Abstract Objective: The study aimed to compare the clinical outcomes of simplified linear plication and classic patch plasty in patients with left ventricular aneurysm (LVA). Methods: We retrospectively reviewed 282 patients undergoing LVA repair between 2006 and 2016. After propensity score matching, 45 pairs of patients receiving LVA surgery were divided into either a patch group (on-pump endoventricular patch plasty) or a plication group (off-pump linear plication). Then, their early surgical outcomes and long-term survival were compared in two matched groups. Results: The heart function improvement at discharge was similar in the two matched groups, while patients in the patch group more commonly suffered from low cardiac output syndrome (P=0.042) with higher proportion of intra-aortic balloon pumping assistance (P=0.034) than patients in the plication group. Compared with patients in the patch group, the patients in the plication group had shorter recovery times, regarding to mechanical ventilation, intensive care unit stay, and hospital stay (P<0.001, P<0.001, and P=0.001, respectively). No significant difference was found in the long-term survival (P=0.62). Conclusions: Off-pump linear plication presented acceptable results in terms of early outcomes and long-term survival. For high-risk patients, the simplified LVA repair technique may be an option.

Humans , Male , Female , Middle Aged , Aged , Heart Aneurysm/surgery , Heart Aneurysm/mortality , Heart Ventricles/surgery , Reference Values , Time Factors , Survival Analysis , Retrospective Studies , Risk Factors , Follow-Up Studies , Treatment Outcome , Statistics, Nonparametric , Propensity Score , Length of Stay , Medical Illustration
Braz. j. otorhinolaryngol. (Impr.) ; 85(2): 176-182, Mar.-Apr. 2019. graf
Article in English | LILACS | ID: biblio-1001553


Abstract Introduction: In rhinoplasty, the nasal dorsum has important relevance regarding the esthetic and functional aspects of the surgery. Its reduction should be performed with maximum accuracy and controlled resection to prevent or minimize potential complications. The septum pyramidal adjustment and repositioning consists of a conservative surgical technique of the nasal dorsum, which does not require the detachment of the upper lateral cartilages of the nasal septum, allowing the remodeling of the nasal dorsum while maintaining esthetic lines and nasal function, potentially reducing frequent complications in more traditional surgeries. Objective: To describe the septum pyramidal adjustment technique in detail, presenting its advantages and disadvantages in relation to the other surgical approaches, as well as to disclose results of this surgical procedure in patients submitted to primary rhinoplasty in a specific hospital. Methods: The medical records of all patients submitted to surgery from 2011 to 2015 through this surgical technique were evaluated by the same team. Of these cases, certain variables were analyzed such as gender, age, indication for reoperation and surgical complications. Results: 153 patients underwent rhinoplasty through septum pyramidal adjustment. Of these, 13 patients experienced an indication for a second surgery and four had some type of postoperative complication. Conclusion: The septum pyramidal adjustment surgical technique is a simple procedure, as it does not require the reconstruction of the nasal dorsum. It has a low number of complications and preserves the anatomical structures.

Resumo Introdução: Na rinoplastia, o dorso nasal tem importante relevância no quadro estético e funcional. A sua redução deve ser realizada com máxima precisão e ressecção controlada a fim de prevenir ou minimizar complicações potenciais. O termo septum pyramidal adjustment and repositioning consiste em uma técnica cirúrgica conservadora do dorso nasal, que não requer a desinserção das cartilagens laterais superiores do septo nasal, que permite remodelar o dorso nasal, manter as linhas estéticas e a função nasal, reduz potencialmente complicações frequentes nas cirurgias mais tradicionais. Objetivo: Descrever em detalhes o septum pyramidal adjustment, expor suas vantagens e desvantagens em relação às outras abordagens cirúrgicas, bem como apresentar resultados desse procedimento cirúrgico em pacientes submetidos à rinoplastia primária em um hospital específico. Método: Foram avaliados os registros médicos de todos os pacientes operados de 2011 a 2015 por essa técnica cirúrgica, pela mesma equipe. Desses casos, foram analisadas algumas variáveis, como: sexo, idade, indicação de reoperação e complicações cirúrgicas. Resultados: Foram submetidos 153 pacientes à rinoplastia por septum pyramidal adjustment. Desses, 13 tiveram segunda indicação cirúrgica e quatro apresentaram alguma complicação pós-operatória. Conclusão: A técnica cirúrgica septum pyramidal adjustment apresenta-se como um procedimento de fácil realização, pois não exige a reconstrução do dorso nasal. Apresenta baixo número de complicações e preserva as estruturas anatômicas.

Humans , Male , Female , Adult , Rhinoplasty/methods , Nasal Cartilages/surgery , Nasal Septum/surgery , Postoperative Complications , Rhinoplasty/adverse effects , Reproducibility of Results , Treatment Outcome , Medical Illustration
Rev. méd. hered ; 30(2): 115-115, abr. 2019. ilus
Article in Spanish | LILACS | ID: biblio-1058678
Hist. ciênc. saúde-Manguinhos ; 26(1): 219-244, Jan.-Mar. 2019. graf
Article in English | LILACS | ID: biblio-989868


Abstract This paper provides an overview of the state of Mexican genetics and biomedical knowledge during the second half of the twentieth century, as well as its impact on the visual representation of human groups and racial hierarchies, based on social studies of scientific imaging and visualization (SIV) and theoretical concepts and methods. It also addresses the genealogy and shifts of the concept of race and racialization of Mexican bodies, concluding with the novel visual culture that resulted from genetic knowledge merged with the racist phenomenon in the second half of the twentieth century in Mexico.

Resumo Este artigo traça um panorama do estado da genética e do conhecimento biomédico no México durante a segunda metade do século XX, assim como seu impacto na representação visual de grupos humanos e hierarquias raciais, baseado em estudos sociais da imagem e visualização cientifica e de seus métodos e conceitos teóricos. Também aborda a genealogia e as mudanças nos conceitos de raça e racismo nos corpos mexicanos, que resultaram na nova cultura visual fruto do conhecimento genético, interligando-se ao fenômeno do racismo na segunda metade do século XX no México.

Humans , History, 19th Century , History, 20th Century , Continental Population Groups/genetics , Biological Evolution , Genetics, Medical/history , Medical Illustration/history , Internationality/history , Racism/history , Mexico
Rev. Assoc. Med. Bras. (1992) ; 65(3): 355-360, Mar. 2019. graf
Article in English | LILACS | ID: biblio-1003039


SUMMARY OBJECT: To explore the treatment effect of the anterior medial neurovascular interval approach to coronal shear fractures of the distal humerus. METHODS: This prospective study included two female patients who were 30-64 years old, with a mean age of 47 years. Fractures were caused by falling from a bicycle. The time between the injury and operation was 1-2 days, with a mean time interval of 1.5 days. Two patients with coronal shear fracture of the distal humerus were treated with open reduction and internal fixation using anterior neurovascular interval approach. RESULTS: There were no intraoperative and postoperative neurological and vascular complications or infections, and the fracture was united. At 12 months after the surgery, the patient returned to work without pain, and with a normal range of motion for elbow and forearm rotation. The X-rays revealed excellent fracture union, no signs of heterotopic ossification, and no traumatic arthritis. According to Mayo's evaluation standards for elbow function, a score of 100 is excellent. CONCLUSIONS: The application of the anterior neurovascular interval approach of the elbow in the treatment of shear fracture of the articular surface of the distal humerus, particularly the trochlea of the humerus, can reduce the stripping of the soft tissue.

RESUMO OBJETIVO: Explorar o efeito do tratamento com uma abordagem anterior do intervalo neurovascular médio para fraturas de cisalhamento coronal da porção distal do úmero. METODOLOGIA: Este estudo prospectivo incluiu duas pacientes do sexo feminino de 30-64 anos de idade, com idade média de 47 anos. As fraturas foram causadas por quedas de bicicleta. O tempo entre a lesão e a operação foi de 1-2 dias, com um intervalo de tempo médio de 1,5 dias. Duas pacientes com cisalhamento coronal da porção distal do úmero foram tratadas com redução aberta e fixação interna utilizando a abordagem anterior do intervalo neurovascular. RESULTADOS: Não houve complicações neurológicas e vasculares intra e pós-operatórias, nem complicações ou infecções, e a fratura foi unida. Após 12 meses da cirurgia, as pacientes retornaram ao trabalho sem dor e com uma amplitude normal de movimento de rotação do antebraço e cotovelo. Os raios-X revelaram excelente união das fraturas, sem sinais de ossificação heterotópica e sem artrite traumática. De acordo com as diretrizes da clínica Mayo para avaliação da função do cotovelo, uma pontuação de 100 é considerada excelente. CONCLUSÃO: A aplicação da abordagem anterior do intervalo neurovascular do cotovelo no tratamento de uma fratura de cisalhamento da superfície articular da porção distal do úmero, especificamente da tróclea do úmero, pode reduzir o desgaste do tecido mole.

Humans , Female , Adult , Vascular Surgical Procedures/methods , Neurosurgical Procedures/methods , Elbow Joint/surgery , Fracture Fixation, Internal/methods , Humeral Fractures/surgery , Humerus/injuries , Time Factors , Prospective Studies , Reproducibility of Results , Follow-Up Studies , Treatment Outcome , Humeral Fractures/physiopathology , Humerus/physiopathology , Medical Illustration , Middle Aged
Rev. bras. cir. cardiovasc ; 34(1): 107-110, Jan.-Feb. 2019. tab, graf
Article in English | LILACS | ID: biblio-985238


Abstract Among all cystic echinococcosis cases, only 0.5%-2% exhibit a cardiac involvement. Only 10% of these become symptomatic. Considering the long time interval between the start of infestation and symptoms to occur, it is hard to diagnose cystic echinococcosis. When detected, even if it is asymptomatic, intramyocardial hydatid cyst requires surgical intervention due to risks of spontaneous rupture and anaphylaxis. In literature, no case of hydatid cyst located in the coronary arterial wall has been reported. Twenty-two-year-old male patient with previous history of pulmonary cystic echinococcosis was referred to us with typical symptoms of coronary artery disease. Coronary cineangiography revealed proximal left diagonal artery (LAD) occlusion. Pre-operative transthoracic echocardiography of the patient planned to undergo coronary artery bypass grafting unveiled an intracoronary calcified cystic mass. In operation, the calcified cystic mass with well-defined borders and size of 2x2 cm located within wall of proximal segment of the LAD artery was excised and double bypass with left internal thoracic artery (LITA) and great saphenous vein grafts to the LAD and first diagonal arteries, respectively, was done. Pathological analysis of the mass revealed it to be an inactive calcified hydatid cyst. Echinococcal IgG-ELISA test was positive. 12-week oral albendazole treatment (2x400 mg/day) was launched postoperatively and the patient was discharged on 7th postoperative day.

Humans , Male , Young Adult , Coronary Artery Disease/parasitology , Echinococcosis/complications , Coronary Artery Disease/surgery , Coronary Artery Disease/diagnostic imaging , Echocardiography , Echinococcosis/surgery , Echinococcosis/diagnostic imaging , Medical Illustration