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1.
An. bras. dermatol ; 96(5): 649-650, Sept.-Oct. 2021. tab
Article in English | LILACS | ID: biblio-1345131
2.
Prensa méd. argent ; 107(2): 66-79, 20210000.
Article in English | LILACS, BINACIS | ID: biblio-1361343

ABSTRACT

Introducción: Se han analizado terapias ayurvédicas y prácticas médicas para un grupo de pacientes en Japón. La característica del tratamiento ayurvédico es una desintoxicación con una gran cantidad de tratamiento con aceite mediante un masaje con aceite en la superficie del cuerpo y una terapia de purificación con ghee o aceite de hierbas especialmente preparado. Los cambios de la microbiota intestinal durante estos tratamientos no han sido bien estudiados. Mé- LA PRENSA MÉDICA ARGENTINA Ayurveda Treatment (Virechana and Basti) and Changes of Intestinal Microbiota at Phyla and Species Level 79 V.107/Nº 2 todo: Los participantes fueron reclutados de la Clínica Hatai Ayurveda en Tokio. La terapia de Virechana, una terapia de purificación o la terapia de Basti (decocción y enema de aceite) se llevó a cabo en 13 pacientes con diversas manifestaciones. Todos los participantes proporcionaron el detalle de su estilo de vida, hábitos dietéticos, enfermedades pasadas y presentes mediante el cuestionario, y se registró la condición precisa durante la admisión al final del campamento. Se tomaron muestras fecales a la entrada, durante el tratamiento, al alta y tres semanas después para analizar la microbiota intestinal por el gen seqyebcubg 16srRNA. Resultados: el peso corporal disminuyó aproximadamente un 5% con la terapia de Virechana, mientras que no ocurrió con Basti, pero la grasa corporal aumentó un 4% (2,2 kg) en promedio en ambos grupos. Varias manifestaciones clínicas de los participantes mejoraron, especialmente en una erupción cutánea y un cambio atópico. El paciente deprimido también remitió mejoras en sus ganas de vivir. En su mayoría son vegetarianos y tenían más Bacteroides (48.09 ± 7.51%), Firmicutes (38.27 ± 10.82%) y Actinobacteria (3.30 ± 3.58%) que los omnívoros que tenían más Proteobacteria (10.73 ± 4.75%), Fusobacteria (2.40 ± 6.25%) y cianobacterias (0,09 ± 0,24%). Cuando los grupos se dividieron por el consumo de aceite, los usuarios de ghee mostraron más Fusobacterium y menos Firmicutes y Actinobacteria. La terapia con Virechana provocó cambios notables en la microbiota después del pretratamiento, como la disminución de Firmicutes y el aumento de Proteobacterias. A nivel género-especie, destacan el aumento de Enterobacteriaceae y la pérdida de Akkermansia municiphila. Niruha Basti y Matra Basti disminuyeron Firmicutes y aumentaron Proteobacteria (p = 0.096). Fusobacterium también aumentó. Después del alta, la Proteobateria se mantuvo alta, pero Firmicutes regresó al 30% en promedio, oscilando entre el 25% y el 50%. Tres semanas después, la variedad aumentó con Fusobacterium, Verrucomicrobia, Tenericutes y Lentisphaerae. La variedad de especies también aumentó tres semanas después. Conclusión: Varias quejas de los participantes mejoraron por el tratamiento ayurvédico con una gran cantidad de tratamiento de aceite por masaje de aceite de superficie corporal y terapia de purga. Causó cambios en la microbiota intestinal y los metabolitos bacterianos pueden afectar las lesiones cutáneas y la salud mental como la sensación depresiva


Subject(s)
Humans , Therapeutics/methods , Body Weight Changes , Herbal Medicine , Feces/microbiology , Ghee , Gastrointestinal Microbiome , Massage/methods , Medicine, Ayurvedic
3.
Saúde Soc ; 29(3): e200364, 2020.
Article in Portuguese | SES-SP, LILACS, SES-SP | ID: biblio-1145109

ABSTRACT

Resumo Durante a última década assistimos ao retrocesso paulatino das políticas públicas de atenção à saúde indígena no Brasil, principalmente no que concerne aos pilares básicos da sua formulação, construídos a partir da década de 1980: atenção específica e diferenciada, participação e controle social. Este texto, apesar de citar alguns momentos críticos desse processo, dá ensejo a algumas reflexões sobre os modos como as políticas e as práticas, essencialmente biomédicas, podem ser compreendidas no contexto mais geral das sociedades indígenas no país.


Abstract Over the past decade, we have seen the gradual setback of public policies for indigenous health care in Brazil, especially with regard to the basic pillars of its formulation, developed from the 1980s onwards: specific and differentiated attention, participation, and social control. This paper, despite mentioning some critical moments in this process, offers an opportunity for some reflections on how policies and practices, essentially biomedical, can be understood in the more general context of indigenous societies in the country.


Subject(s)
Humans , Male , Female , Public Policy , Health of Indigenous Peoples , Health Policy , Medicine, Ayurvedic
4.
Fractal rev. psicol ; 31(spe): 220-227, set.-dez. 2019.
Article in Portuguese | LILACS, INDEXPSI | ID: biblio-1056232

ABSTRACT

Apesar da crítica à concepção cartesiana do ser humano, faltam modelos teórico-conceituais que superaram suas limitações, a despeito do destaque dado à integralidade no Brasil. A base filosófica que fundamenta as abordagens dominantes é implícita, até nos modelos orientais importados como nas medicinas tradicionais e Práticas Integrativas Complementares (PICs) que, a partir de 2006, são promovidas no SUS pela Política Nacional das Práticas Integrativas Complementares e portarias. Descontextualizadas, as adaptações e criações de novas modalidades de PICs orientais se desfiguram a partir de interesses comerciais e desconhecimento de seu histórico. A integralidade é perdida, pois a PIC é fragmentada e isolada no modelo biomédico mecanicista e biologicista. Este artigo objetiva apresentar as premissas filosóficas indianas dos tantras em seu contexto histórico, como fundamento para o Ayurveda, e as práticas contemplativas que visam o desenvolvimento espiritual. Sua breve contextualização baseia-se nas análises acadêmicas de textos históricos em sânscrito, como também de autores e mestres de tradições espirituais asiáticos e ocidentais. Os conceitos de mente, corpo, awareness e energia integram esta abordagem não dual, onde predomina a imanência. Revelam uma compreensão da natureza humana integrada com o universo de modo complexo e dinâmico, desenvolvida e pesquisada ao longo de milhares de anos.(AU)


Abstract Despite the widespread critique of the hegemonic Cartesian view of human nature, no alternatives adequately surpass its limitations in the field of health. The philosophical base which informs these western dominant approaches is implicit, even when eastern health practices are imported. These have been acknowledged and promoted in the public healthcare system in Brazil since the 2006 health policy and later government decrees. Adaptations and western creations based on eastern practices are severed from their original tenets, fueled by commercialism and ignorance of its history. In the process, its integrative approach is lost, as the complementary health practice is used in psychology or in the mechanical and biologizing biomedical model. This article thus presents the philosophical Indian tenets of the Tantras in their historical context, as a foundation for Ayurveda and the contemplative practices aimed at spiritual development. Its brief and necessarily incomplete contextualization is based on academic analysis of historical sanskrit texts by scholars, Indian, American and Tibetan authors and teachers of lineage traditions. The concepts of mind, body, awareness and energy compose this nondual approach to human nature integrated with the universe in a complex and dynamic way, developed and researched throughout thousands of years.(AU)


Subject(s)
Yoga , Meditation , Mind-Body Relations, Metaphysical , Medicine, Ayurvedic , India
5.
J. coloproctol. (Rio J., Impr.) ; 39(4): 389-393, Oct.-Dec. 2019. tab, ilus
Article in English | LILACS | ID: biblio-1056636

ABSTRACT

Abstract Rectal Prolapse is a condition where the rectum protrudes beyond the anus. The explanation of this condition can be traced back to ancient Ayurveda text like Susruta Samhita, Ebers Pappyrus of 1500 B.C., etc. The exact cause of rectal prolapse is unclear but it is predominant on female gender and on people having constipation, previous anorectal surgeries etc. Both partial and complete varieties of rectal prolapse are extremely debilitating because of the discomfort of the prolapsing mass and variety of symptoms like rectal bleed, intermittent constipation or fecal incontinence. Although, diverse modalities of surgical management of rectal prolapse are present, no single optimal procedure is proved and the choice of operation is determined by the patient's age, sex, degree of incontinence, operative risk, as well as by the surgeon's experience. In Ayurveda, Guda Bhramsa (Rectal prolapse) is explained by Acharya Susruta under Kshudra Rogas (chapter of minor diseases) and has elaborated it's conservative management very beautifully. In this case, a female with partial rectal prolapse was treated with Kshara application and managed without complications. So, Kshara application can be a safe and effective alternative for the management of rectal prolapse.


Resumo O prolapso retal é uma condição em que o reto se projeta para além do ânus. A explicação desta condição foi relatada em antigos textos Ayurveda como Susruta Samhita e Ebers Pappyrus, datados de 1500 aC. A causa exata do prolapso retal não é clara, mas essa condição é predominante no sexo feminino e nas pessoas com constipação e histórico de cirurgias anorretais anteriores. Tanto o prolapso retal parcial quanto total são extremamente debilitantes devido ao desconforto da massa prolapsante e da variedade de sintomas como sangramento retal, constipação intermitente ou incontinência fecal. Embora diversas modalidades de tratamento cirúrgico para corrigir o prolapso retal tenham sido relatadas na literatura, nenhum procedimento é consensual; a escolha da operação é determinada pela idade, sexo, grau de incontinência, risco operatório e experiência do cirurgião. Na Ayurveda, Guda Bhramsa (prolapso retal) é explicado por Acharya Susruta no Kshudra Rogas (capítulo de doenças menores) e seu manejo conservador é descrito de forma bastante completa. No presente caso, uma paciente do sexo feminino com prolapso retal parcial foi tratada com aplicação de Kshara e administrada sem complicações. Assim, a aplicação de Kshara pode ser uma alternativa segura e eficaz para o manejo do prolapso retal.


Subject(s)
Humans , Female , Adult , Cautery , Rectal Prolapse/surgery , Medicine, Ayurvedic , Rectal Prolapse/therapy , India , Medicine, Ayurvedic/history
6.
HerbalGram ; 119: 62-71, 2018. tab, graf, ilus
Article in English | MTYCI, LILACS, MTYCI | ID: biblio-980304

ABSTRACT

In 2017, retail sales of herbal dietary supplements in the United States surpassed $8 billion for the first time, reaching an estimated total of $8.085 billion. Consumer spending increased by approximately $633 million, or 8.5%, from 2016 ­ the strongest US sales growth for herbal supplements in more than 15 years. Total US retail sales have increased every year since 2004, and since then, consumer spending on herbal supplements has nearly doubled.


Subject(s)
Humans , Plants, Medicinal , Dietary Supplements/economics , Marrubium , Curcuma , Medicine, Ayurvedic
7.
Article in English | WPRIM | ID: wpr-346272

ABSTRACT

The term Kriyakala refers to the recognition of the stage of a disease's progress, which helps to determine appropriate measure to correct the imbalance in Doshas (biological factors). It is a compound expression, comprised of Kriya and Kala, where Kriya means the choice to treatment (medicine, food and daily-routine) used to improve the disturbance in Doshas, and Kala refers to the stage of progress of a disease. Sushruta, an ancient Indian surgeon, has described the concept of Kriyakala in Varnaprashnadhyaya, an ancient Vedic Sanskrit text, which seeks to explain the incidence of Varnas in terms of Doshic disturbances. Varna, in modern parlance, may be described as an inflammatory process that may lead ulceration and chronic inflammation, promoting all stages of carcinogenesis. Abnormal interactions between Prakriti (genotype) and environmental factors vitiate the Doshas and impair immunity, which can lead to aberrant cell growth and cancer. Moreover, the interaction between vitiated Doshas and weak Dhatus (body tissues) manifests as cancers of a specific organ. Shatkriyakala (six stages of progress of a disease), on the other hand, provides a framework to assess the cancer and its pathogenesis in different stages. According to Ayurvedic concepts, all cancer therapies treat the affected tissues indirectly by eliminating vitiated Doshas, rejuvenating Dhatus and restoring immunity in cancer patients. The present review describes the six stages of Shatkriyakala in detail, with an emphasis on research areas to validate the concept of Shatkriyakala. This traditional knowledge can be utilized with modern technologies to detect predisposition for cancer or diagnose cancer in its early stages.


Subject(s)
Early Detection of Cancer , Humans , Medicine, Ayurvedic , Neoplasm Staging , Neoplasms , Therapeutics
8.
Braz. j. pharm. sci ; 52(3): 433-442, July-Sept. 2016. tab, graf
Article in English | LILACS | ID: biblio-828269

ABSTRACT

ABSTRACT Punarnava (Boerhaavia diffusa L.- Nyctaginaceae) is a promising drug to rejuvenate new cells in the body. It is well known in Ayurvedic medicine and locally called Tambadivasu. Superficially it is similar to other species of Boerhaavia and species of Trianthema and Sesuvium. Due to the minute morphological differences, the above plants are erroneously used in medicine as Punarnava, and at times on purpose as an adulterant. Therefore, it is necessary to highlight the anatomical features of Punarnava for proper identification of the medicinal plant species for local people and for scientific research. Due to the ambiguity in local names and similar apparent appearance, market samples of Punarnava are often adulterated with various species of Trianthema and Sesuvium. These adulterated samples contain neither the Punarnavine alkaloid, nor does it possess anisocytic stomata but possess paracytic stomata. Comparative study of stem anatomy showed two main characteristic differences. First, plenty of starch grains can be seen in both the ground parenchymatous tissues present in between successive cambia and xylem parenchyma of Punarnava which is not observed in species of Trianthema, and second, the phloem around the xylem of Punarnava root has semi-circular or eccentric patches, while that of Trianthema only has narrow strips. This study is focused on comparative SEM study of leaf morphologies and anatomy of leaf, stem, and root of Boerhaavia diffusa L., Trianthema portulacastrum L. and Sesuvium portulacastrum L.


Subject(s)
Comparative Study , Nyctaginaceae/anatomy & histology , Medicine, Ayurvedic , Microscopy, Electron/methods , Plants, Medicinal/anatomy & histology
10.
Article in English | WPRIM | ID: wpr-317049

ABSTRACT

<p><b>OBJECTIVE</b>Ayurvedic formulations are preferred over other formulations as well as commercialized on broad level to treat various ailments. The World Health Organization has established certain guidelines for quality control of heavy metals and pesticide residues. Bacopa monnieri, a popular herb with immunomodulator and memory-enhancing properties is the chief constituent of several Ayurvedic formulations, which include Brahmi Vati (BV), Brahmi Ghrita (BG) and Saraswat Churna (SC), etc. In view of the World Health Organization guidelines, two products of each formulation from six different manufacturers were purchased from Ayurvedic Pharmacy, Bulanala-Varanasi, India for testing heavy metal and pesticide residue.</p><p><b>METHODS</b>In the present study, all the formulations--BV, BG and SC--were selected for estimation of four heavy metals namely lead (Pb), cadmium (Cd), chromium (Cr) and nickel (Ni) by a plasma emission spectrophotometer. Organochlorine pesticidal residues were estimated for dichlorodiphenyl trichloroethane, isomers of hexachlorocyclohexane (HCH) and α-endosulfan, etc. in total 12 samples of test formulations containing Bacopa monnieri L. using gas chromatography technique.</p><p><b>RESULTS</b>Out of 12 samples, Pb, Cd, Cr and Ni were present in all samples but below the permissible limit. Although atrazine, aldrin, dialdrin were in below detection limit, but other pesticides were detected in some samples as oxamyl, hexachlorocyclohexanes (α-HCH, β-HCH and γ-HCH), dichlorodiphenyl trichloroethane and dichlorodiphenyl dichloroethylene.</p><p><b>CONCLUSION</b>The presence of heavy metals in the formulations was low to cause toxicity. However evaluation of heavy metals and pesticide residue in every batch is necessary.</p>


Subject(s)
Bacopa , Chemistry , Chemistry, Pharmaceutical , Medicine, Ayurvedic , Metals, Heavy , Pesticides
11.
Article in Korean | WPRIM | ID: wpr-8016

ABSTRACT

Nearly nothing is known of medicine in ancient Korea due to insufficient materials. With several extant prescriptions and esoteric methods of treating diseases alone, it is impossible to gauge in depth the management of medicine during this period. If one exception were to be cited, that would be the fact that the annotations for understanding the contents on Indian medicine in the “Chapter on Eliminating Disease” in the Sutra of Golden Light, a Buddhist sutra originating from India, reflected the medical knowledge of Buddhist monks from Silla (新羅, 57 BC-935 AD) who were active immediately after the nation's unification of the two other kingdoms on the Korean Peninsula (668 AD) such as Wonhyo (元曉, 617-686 AD), Gyeongheung (憬興, 620?-700? AD), and Seungjang (勝莊, 684-? AD). Along with those by other monks, these annotations are collected in the Mysterious Pivot of the Sutra of Golden Light (金光明經最勝王經玄樞), which was compiled by Gangyō(願曉, 835-871 AD), a Japanese monk from the Heian era (平安, 794-1185 AD). Representative versions of the “Chapter on Eliminating Disease” in the Sutra of Golden Light include: a classical Chinese translation by the Indian monk Dharmakṣema (曇無讖, 385-433 AD); the eight-volume edition by Chinese monk Baogui (寶貴), which differs little from the preceding work in terms of the contents of the “Chapter on Eliminating Disease”; and the ten-volume edition by Yijing (義淨, 635-713 AD), who had full-fledged knowledge of Indian medicine. When the contents of the annotations thus collected are examined, it seems that Wonhyo had not been aware of the existence of the ten-volume edition, and Gyeongheung and Seungjang most certainly used the ten-volume edition in their annotations as well. Especially noteworthy are Wonhyo's annotations on the Indian medical knowledge found in the “Chapter on Eliminating Disease” in the Sutra of Golden Light. Here, he made a bold attempt to link and understand consistently even discussions on Indian and Buddhist medicine on the basis of the traditional East Asian medical theory centering on the yin-yang (陰陽) and five phases (五行, wuxing). In accordance with East Asia's theory of the seasonal five phases, Wonhyo sought to explain aspects of Indian medicine, e.g., changes in the four great elements (四大, catvāri mahā-bhūtāni) of earth, water, fire, and wind according to seasonal factors and their effect on the internal organs; patterns of diseases such as wind (vāta)-induced disease, bile (pitta)-induced disease, phlegm (śleṣman)-induced disease, and a combination (saṃnipāta) of these three types of diseases; pathogenesis due to the indigestion of food, as pathological mechanisms centering on the theory of the mutual overcoming (相克, xiangke) of the five phases including the five viscera (五藏, wuzang), five flavors (五味, wuwei), and five colors (五色, wuse). They existed in the text contents on Indian medicine, which could not be explicated well with the existing medical knowledge based on the theory of the five phases. Consequently, he boldly modified the theory of the five phases in his own way for such passages, thus attempting a reconciliation, or harmonization of disputes (和諍, hwajaeng), of the two medical systems. Such an attempt was even bolder than those by earlier annotators, and Wonhyo's annotations came to be accepted by later annotators as one persuasive explanation as well. In the case of Gyeongheung and Seungjang, who obtained and examined the ten-volume edition, a new classical Chinese translation produced following Wonhyo's death, annotated the “Chapter on Eliminating Disease” based on their outstanding proficiency in Sanskrit and knowledge of new Indian and Buddhist medicine. This fact signifies that knowledge of the eight arts (八術) of Ayurvedic medicine in India was introduced into Silla around the early 8th century. The medical knowledge of Wonhyo, Gyeongheung, and Seungjang demonstrates that intellectual circles in contemporary Silla were arenas in which not only traditional East Asian medicine as represented by works such as the Inner Canon of the Yellow Emperor (黃帝內經, Huangdi Neijing) but also Indian medicine of Buddhism coexisted in almost real time.


Subject(s)
Asian Continental Ancestry Group , Bile , Buddhism , Dissent and Disputes , Dyspepsia , Fires , History of Medicine , Humans , India , Korea , Medicine, Ayurvedic , Medicine, East Asian Traditional , Monks , Prescriptions , Seasons , Viscera , Water , Wind , Yin-Yang
12.
Indian J Exp Biol ; 2015 Mar; 53(3): 158-163
Article in English | IMSEAR | ID: sea-158406

ABSTRACT

Chyawanprash is an ayurvedic formulation used in Indian traditional medicinal system for its beneficial effect on human health. We investigated the immunostimulatory effects of Chyawanprash (CHY) using in vitro assays evaluating the secretion of cytokines such as Tumor Necrosis Factor-alpha (TNF-α), Interleukin-1beta (IL-1β) and Macrophage Inflammatory Protein-1-alpha (MIP-1-α) from murine bone marrow derived Dendritic Cells (DC) which play pivotal role in immunostimulation. The effects of CHY on phagocytosis in murine macrophages (RAW264.7) and Natural Killer (NK) cell activity were also investigated. At non-cytotoxic concentrations (20–500 µg/ml), CHY enhanced the secretion of all the three cytokines from DC. CHY also stimulated both, macrophage (RAW264.7) as well as NK cell activity, in vitro. In conclusion, the data substantiates the immunoprotective role of CHY at cellular level mediated by immunostimulation in key immune cells viz. dendritic Cells, macrophages and NK cells.


Subject(s)
Adjuvants, Immunologic/pharmacology , Animals , Cell Line , Cytokines/analysis , Cytotoxicity, Immunologic/drug effects , Dendritic Cells/drug effects , Drug Evaluation, Preclinical , In Vitro Techniques , Killer Cells, Natural/drug effects , Macrophages/drug effects , Male , Medicine, Ayurvedic , Mice , Mice, Inbred C57BL , Phagocytosis/drug effects , Plant Preparations/pharmacology , Specific Pathogen-Free Organisms , Spleen/cytology , Zymosan
13.
Article in English | IMSEAR | ID: sea-158414

ABSTRACT

Background & objectives: In the traditional system of medicine in India Ashwagandha powder and Sidh Makardhwaj have been used for the treatment of rheumatoid arthritis. However, safety and efficacy of this treatment have not been evaluated. Therefore, the present study was carried out to evaluate the efficacy and safety of Ayurvedic treatment (Ashwagandha powder and Sidh Makardhwaj) in patients with rheumatoid arthritis. Methods: One hundred and twenty five patients with joint pain were screened at an Ayurvedic hospital in New Delhi, India. Eighty six patients satisfied inclusion criteria and were included in the study. Detailed medical history and physical examination were recorded. Patients took 5g of Ashwagandha powder twice a day for three weeks with lukewarm water or milk. Sidh Makardhwaj (100 mg) with honey was administered daily for the next four weeks. The follow up of patients was carried out every two weeks. The primary efficacy end point was based on American College of Rheumatology (ACR) 20 response. Secondary end points were ACR50, ACR70 responses, change from baseline in disease activity score (DAS) 28 score and ACR parameters. Safety assessments were hepatic function [alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), bilirubin and β2 microglobulin], renal function (urea and creatinine and NGAL) tests and urine mercury level. Results: The study was completed by 90.7 per cent (78/86) patients. Patients with moderate and high disease activity were 57.7 per cent (45/78) and 42.3 per cent (33/78), respectively. All patients were tested positive for rheumatoid factor and increased ESR level. Ashwagandha and Sidh Makardhwaj treatment decreased RA factor. A significant change in post-treatment scores of tender joint counts, swollen joint counts, physician global assessment score, patient global assessment score, pain assessment score, patient self assessed disability index score and ESR level were observed as compared to baseline scores. ACR20 response was observed in 56.4 per cent (44/78) patients (American College of Rheumatology criteria) and moderate response in 39.74 per cent (31/78) patients [European League Against Rheumatism (EULAR) criteria]. Ayurvedic treatment for seven weeks in rheumatoid arthritis patients showed normal kidney and liver function tests. However, increased urinary mercury levels were observed after treatment. Interpretation & conclusions: The findings of the present study suggest that this Ayurvedic treatment (Ashwagandha powder and Sidh Makardhwaj) has a potential to be used for the treatment of rheumatoid arthritis. However, due to small sample size, short duration, non randomization and lack of a control group as study limitations, further studies need to be done to confirm these findings.


Subject(s)
Arthritis, Rheumatoid/therapy , Humans , India , Medicine, Ayurvedic , Plant Extracts/pharmacology , Plant Extracts/therapeutic use , Withania/pharmacology , Withania/therapeutic use
14.
Buenos Aires; s.n; 2015. 1-66 p. tab.
Thesis in Spanish | MTYCI, LILACS, MTYCI | ID: biblio-1007528

ABSTRACT

El ayurveda es una medicina milenaria de la india de creciente presencia en argentina. Damos cuenta en este trabajo de aspectos comunes en el proceso de transnacionalización del ayurveda, y de rasgos locales en la dinámica de recepción por parte de sus seguidores en argentina. En los últimos años el circuito local de especialistas, en nicho comercial de productos y alimentos ayurvedicos y las organizaciones vinculadas con la disciplina, han crecido como parte del campo en expansión de las medicinas alternativas y las subculturas alimentarias. El Ayurveda es promovido como una Medicina Holística, para aquellos dispuestos a cultivar estilos de vida saludables y dedicar tiempo y esfuerzo al cuidado personal. Las consultas médicas y los tratamientos no son parte de las prestaciones de la seguridad social, ni de los servicios públicos, ni los planes de medicina privado, constituyendo un gasto del bolsillo accesible a los sectores medios y altos. A raíz del creciente descreimiento por la medicina occidental, se ha incrementado el interés por diferentes metodologías alternativas. Pocos estudios han sido realizados sobre los beneficios de la Medicina Ayurveda y la relación con un estilo de vida saludable, como tratamiento preventivo de diversas dolencias. (AU)


Subject(s)
Humans , Complementary Therapies , Medicine, Ayurvedic , Argentina , Healthy Lifestyle
15.
Article in English | WPRIM | ID: wpr-310872

ABSTRACT

<p><b>OBJECTIVE</b>To study and compare the conventional extraction procedure with microwave assisted extraction (MAE) for some Ayurvedic Rasayana drugs and to evaluate their antioxidant potential and carry out the characterization of extracts by thin layer chromatography.</p><p><b>METHODS</b>Three Ayurvedic rasayana plants Allium sativum Linn., Bombax ceiba Linn. and Inula racemosa Hook. were evaluated for an improved MAE methodology by determining the effects of grinding degree, extraction solvent, effect of dielectric constant and duration of time on the extractive value. Antioxidant potential of all three drugs was evaluated with 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and reducing power was determined by using Gallic acid as standard. Further thin layer chromatographic (TLC) analysis was performed on pre-activated Silica Gel G plates and Rf value were compared with those reported for the important biomarkers.</p><p><b>RESULTS</b>The total extractive value for Allium sativum Linn. was 36.95% (w/w) and 49.95% (w/w) for ethanol extraction respectively. In case of Bombax ceiba Linn. the yield of aqueous extract by MAE was 50% (w/w) compared to 42% (w/w) in ethanol (50% v/v). Percent yield of Inula racemosa Hook. in aqueous extract was found to be 27.55% (w/w) which was better than ethanol extract (50%) where the yield was 25.95% (w/w). Upon antioxidant activity evaluation. sativum extract showed an absorbance of 0.980±0.92 at concentration of 500 μg with maximum reducing capacity. This was followed by. ceiba Linn. 0.825±0.98 and. racemosa Hook. with 0.799±2.01 at a concentration of 500 μg. TLC based standardization of. sativum Linn. extract shows single spot with Rf value of 0.38, B. ceiba Linn. extract shows Rf values were 0.23, 0.58, 0.77, 0.92 and I. racemosa Hook. extract spot had a Rf value of 0.72.</p><p><b>CONCLUSIONS</b>A significant improvement in extractive values was observed as a factor of time and other advantages by using MAE technology. All three drugs have high antioxidant potential and a TLC profiling similar to reported ones. The presence of fructan type polysaccharide can be further utilized for bioactivity directed fractionation and evaluation of immunomodulatory activity.</p>


Subject(s)
Antioxidants , Pharmacology , Biphenyl Compounds , Chemistry , Chromatography, Thin Layer , Methods , Ethanol , Chemistry , Free Radical Scavengers , Pharmacology , Inhibitory Concentration 50 , Medicine, Ayurvedic , Microwaves , Oxidation-Reduction , Pharmaceutical Preparations , Picrates , Chemistry , Plants, Medicinal , Chemistry , Solvents , Time Factors
16.
Journal of Integrative Medicine ; (12): 115-121, 2015.
Article in English | WPRIM | ID: wpr-317099

ABSTRACT

<p><b>OBJECTIVE</b>The purpose of the present study was to evaluate the nephroprotective and antioxidant properties of Triphala against bromobenzene-induced nephrotoxicity in female Wistar albino rats.</p><p><b>METHODS</b>Animals were divided into five groups of six rats and treated as follows: Group I was a normal control and received no treatment, Group II received only bromobenzene (10 mmol/kg), Groups III and IV received bromobenzene and Triphala (250 and 500 mg/kg, respectively), Group V received Triphala alone (500 mg/kg), and Group VI received bromobenzene and silymarin (100 mg/kg). Antioxidant status and serum kidney functional markers were analyzed.</p><p><b>RESULTS</b>Bromobenzene treatment resulted in significant (P< 0.05) decreases in the activities of antioxidant enzymes such as catalase, superoxide dismutase, glutathione-S-transferase and glutathione peroxidase as well as total reduced glutathione. There was a significant (P< 0.05) increase in lipid peroxidation in kidney tissue homogenates. There were significant (P< 0.05) reductions in the levels of serum total protein and albumin as well as significant (P< 0.05) increases in serum creatinine, urea and uric acid. The oral administration of two different doses (250 and 500 mg/kg) of Triphala in bromobenzene-treated rats normalized the tested parameters. The histopathological examinations of kidney sections of the experimental rats support the biochemical observations.</p><p><b>CONCLUSION</b>Triphala treatment alleviated the nephrotoxic effects of bromobenzene by increasing the activities of antioxidant enzymes and reducing the levels of lipid peroxidation and kidney functional markers.</p>


Subject(s)
Acute Kidney Injury , Diagnosis , Metabolism , Animals , Antioxidants , Pharmacology , Bromobenzenes , Pharmacology , Disease Models, Animal , Female , Kidney , Metabolism , Pathology , Kidney Function Tests , Medicine, Ayurvedic , Phyllanthus emblica , Plant Preparations , Chemistry , Pharmacology , Plant Structures , Protective Agents , Pharmacology , Rats , Rats, Wistar , Silymarin , Pharmacology , Terminalia , Treatment Outcome
17.
Article in English | IMSEAR | ID: sea-157661

ABSTRACT

This study is conducted to evaluate the efficacy and safety of the poly herbal drug preparation “Jod Aram” in Rheumatoid arthritis patients. The ingredients are hydro alcoholic extraction of different parts of plants. Material and method: A double blind, randomized, fixed dose, placebo controlled clinical trial using “Jod Aram” was carried out on 24 (14 Patients of “Jod Aram” and 10 patients on placebo) patients of rheumatoid arthritis, who were followed up for a period of 6 months. Result: There is significant improvement in clinical variables of rheumatoid arthritis in “Jod Aram” group compared to placebo at the end of 24 weeks of randomization trial. The drug is most effective in reducing pain and tenderness in the joint as the observed p value < 0.001. It is also effective in reducing signs of inflammation and improving disability associated with arthritis. Conclusion: This randomized drug trial demonstrated potential efficacy, safety in symptomatic treatment of rheumatoid arthritis over 24 weeks.


Subject(s)
Adult , Arthritis, Rheumatoid/drug therapy , Arthritis, Rheumatoid/epidemiology , Female , Humans , Male , Medicine, Ayurvedic , Middle Aged , Placebos , Plants, Medicinal/drug effects , Plants, Medicinal/therapeutic use , Randomized Controlled Trials as Topic
19.
Indian J Exp Biol ; 2014 Feb; 52(2): 103-111
Article in English | IMSEAR | ID: sea-150338

ABSTRACT

Role of herbal drugs and medicinal plant extracts in the successful treatment of urolithiasis, classified as the third most common urinary tract diseases is well documented. Ayurvedic plants and their components mediate antilithogenic effects by altering ionic composition of urine, being diuretic, antioxidant or having antimicrobial activity. Therapeutic peptides and proteins have unique place in pharmaceutical biotechnology due to their critical roles in cell biology. The innovation in antilithiatic proteins is that they are anionic, rich in acidic amino acids which make oxalate unavailable by interacting with calcium and have EF Hand domain which is a characteristic feature of various calcium binding protein like calgranulin, osteopontin. The review provides a background on the pathogenesis of urolithiasis and medical treatments. It focusses on the present research evaluating the scientific basis of antilithiatic potential of various plants and role of plant proteins as therapeutic agents thus opening new vista in the management of urolithiasis. Further investigations are required to fully decipher the mode of action of the potent biomolecules so as to exploit their preventive and therapeutic potential.


Subject(s)
Humans , Leukocyte L1 Antigen Complex/therapeutic use , Medicine, Ayurvedic , Osteopontin/therapeutic use , Phytotherapy , Plant Extracts/chemistry , Plant Extracts/therapeutic use , Urolithiasis/drug therapy , Urolithiasis/pathology
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