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1.
Article in Korean | WPRIM | ID: wpr-227513

ABSTRACT

Mantle cell lymphoma (MCL) is an uncommon type of gastrointestinal lymphoma. MCL is a distinct subtype of B-cell non-Hodgkin lymphomas. The major subtype of MCL is characterized by the presence of multiple lymphomatous polyposis (MLP), in which multiple polyps are observed along the gastrointestinal tract. The malignant cells express pan B-cell marker and the T-cell marker cluster of differentiation 5. The chromosomal translocation t(11;14)(q13;q32) that causes cyclin D1 overexpression is commonly observed on the cytogenetic analysis of MCL. Survival improvement has recently been achieved for patient with MCL by the successful introduction of monoclonal antibodies and dose-intensified approaches for treatment, including autologous stem cell transplantation strategies. Some reports suggest that there is an increased incidence of second malignancies in patients with MCL or lymphoma. We report a case of MCL involving the colon; the patient was a 60-year-old man who complained of low abdominal discomfort during defecation. During the workup, a meningioma was unexpectedly discovered. On analysis, the tumor was found to be a t(11;14)-negative and non-MLP-type MCL.


Subject(s)
Chromosomes, Human, Pair 11 , Chromosomes, Human, Pair 14 , Cyclin D1/metabolism , Humans , Lymphoma, Mantle-Cell/diagnosis , Magnetic Resonance Imaging , Male , Meningeal Neoplasms/complications , Meningioma/complications , Middle Aged , Positron-Emission Tomography , Translocation, Genetic
2.
Article in English | WPRIM | ID: wpr-119893

ABSTRACT

Multiple endocrine neoplasia type 1 (MEN1) syndrome includes varying combinations of endocrine and non-endocrine tumors. There are also a considerable number of atypical MEN1 syndrome. In this case, a 68-yr-old woman was referred to the Department of Endocrinology for hypercalcemia. Five years ago, she had diagnosed as primary hyperaldosteronism and now newly diagnosed as parathyroid hyperplasia with laboratory and pathologic findings. Hurthle-cell thyroid cancer was also resected during the parathyroid exploration and small meningioma was found on brain MRI. Her general condition has markedly improved and her adrenal mass and meningioma are being closely observed now. We could find the loss of heterozygosity of the MEN1 locus in parathyroid glands, suggesting a MEN1-related tumor, but not a germline mutation. Considering a variety of phenotypic expression and a limitation of current molecular analysis, periodic follow up will be needed in patients with a MEN1-like phenotype.


Subject(s)
Aged , Base Sequence , Brain/diagnostic imaging , Female , Humans , Hyperaldosteronism/complications , Hyperparathyroidism, Primary/diagnosis , Loss of Heterozygosity , Magnetic Resonance Imaging , Meningeal Neoplasms/complications , Meningioma/complications , Mutation , Parathyroid Glands/pathology , Proto-Oncogene Proteins/genetics , Sequence Analysis, DNA , Thyroid Neoplasms/complications , Tomography, X-Ray Computed
3.
Arq. neuropsiquiatr ; 68(3): 346-349, June 2010. ilus, graf
Article in English | LILACS | ID: lil-550263

ABSTRACT

Occurrence of peritumoral brain edema (PBE) in meningiomas has been associated with several factors in recent years, although its pathophysiological mechanism has not yet been fully elucidated. The aim of this study was to analyze the correlation between the presence / degree of PBE and factors such as gender, age, size and histological subtype of tumor. We analyzed the MRI images of 74 patients operated on Hospital Beneficência Portuguesa de Porto Alegre for the presence / degree of PBE and data was statistically correlated with the parameters of the patient. PBE was present in 70.1 percent of patients. Tumors with higher volume had more PBE. Tumors of the olfactory groove showed more PBE than sphenoid wing and parassagittal tumors. Transitional subtype showed more PBE than fibroblastic and meningothelial subtypes.


A presença de edema cerebral peritumoral (ECP) em meningiomas tem sido associada a diversos fatores nos últimos anos, embora o seu mecanismo fisiopatológico ainda não tenha sido inteiramente elucidado. O objetivo desse estudo foi analisar a correlação entre a presença/grau de ECP e fatores como sexo, idade, volume e subtipo histológico do tumor. Foram analisadas imagens de RM de 74 pacientes operados no Hospital Beneficência Portuguesa de Porto Alegre quanto à presença/grau de ECP e os dados correlacionados estatisticamente com os parâmetros do paciente. ECP estava presente em 70,1 por cento dos pacientes. Tumores com maior volume apresentaram mais ECP. Tumores da goteira olfatória apresentaram mais ECP que os da asa do esfenóide e que os parassagitais. Meningiomas transicionais apresentaram mais ECP que os fibroblásticos e que os meningoteliais.


Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Brain Edema/pathology , Meningeal Neoplasms/pathology , Meningioma/pathology , Age Factors , Brain Edema/etiology , Magnetic Resonance Imaging , Meningeal Neoplasms/complications , Meningioma/complications , Retrospective Studies , Severity of Illness Index , Sex Factors , Tumor Burden , Young Adult
7.
Article in English | WPRIM | ID: wpr-65670

ABSTRACT

Meningioma rarely manifests as a subarachnoid hemorrhage (SAH), and invasion directly into a major intracranial artery is extremely rare. To the best of our knowledge, meningioma presenting with an SAH associated with major intracranial arterial invasion has never been reported. We present a case of sphenoid ridge meningotheliomatous meningioma manifesting as an SAH without pathologically atypical or malignant features, due to direct tumor invasion into the middle cerebral artery.


Subject(s)
Humans , Male , Meningeal Neoplasms/complications , Meningioma/complications , Middle Aged , Middle Cerebral Artery/pathology , Neoplasm Invasiveness , Skull Neoplasms/complications , Sphenoid Bone , Subarachnoid Hemorrhage/etiology
8.
Int. j. odontostomatol. (Print) ; 1(2): 157-159, Dec. 2007. ilus
Article in Spanish | LILACS | ID: lil-533371

ABSTRACT

La neuralgia del trigémino es una patología que se caracteriza por un dolor paroxístico ante estímulos inocuos, principalmente tactiles y que afecta a una de las divisiones del nervio trigémino. En este artículo se presenta un caso de neuralgia secundaria a la compresión del ganglio trigeminal, producto de un meningioma del ligamento petroclinoideo y una breve revisión de la literatura.


The trigeminal neuralgia is a pathology that is characterized by a paroxictic pain before innocuous stimuli, mainly tactile and that it affects one of the divisions of the trigeminal nerve. In this article we present a case of secondary trigeminal neuralgia, due to meningioma of the petroclinoid ligament and a brief revision of the literature.


Subject(s)
Humans , Female , Aged , Meningioma/complications , Meningeal Neoplasms/complications , Trigeminal Neuralgia/etiology , Constriction, Pathologic , Facial Pain/etiology , Trigeminal Nerve/pathology
9.
Neurol India ; 2003 Sep; 51(3): 419-21
Article in English | IMSEAR | ID: sea-121569

ABSTRACT

A case of falcine meningioma associated with acute subdural hemorrhage is reported. The possible mechanisms of hemorrhage in the case are discussed. We believe that an early recognition and surgery can prevent neurological deterioration.


Subject(s)
Aged , Hematoma, Subdural/etiology , Humans , Male , Meningeal Neoplasms/complications , Meningioma/complications , Tomography, X-Ray Computed
10.
Neurol India ; 2001 Dec; 49(4): 398-400
Article in English | IMSEAR | ID: sea-120736

ABSTRACT

The co-existence of schwannoma and meningioma as a mixed intracranial tumour is uncommon and so far only eight cases have been published in the literature. Because of rarity, we report a unique case of mixed tumour having schwann cell and meningeal components, in a patient with neurofibromatosis type -2 (NF-2). The possible mechanisms for the occurrence of these mixed tumours are discussed.


Subject(s)
Adult , Brain Neoplasms/complications , Humans , Magnetic Resonance Imaging , Male , Meningeal Neoplasms/complications , Meningioma/complications , Neoplasms, Complex and Mixed/complications , Neurilemmoma/complications , Neurofibromatosis 2/complications
12.
Neurol India ; 2001 Jun; 49(2): 204-6
Article in English | IMSEAR | ID: sea-119959

ABSTRACT

Two unusual cases of meningiomas associated with opposite chronic subdural haematoma are presented.


Subject(s)
Aged , Brain/diagnostic imaging , Chronic Disease , Hematoma, Subdural/etiology , Humans , Male , Meningeal Neoplasms/complications , Meningioma/complications , Tomography, X-Ray Computed
13.
Article in English | WPRIM | ID: wpr-156187

ABSTRACT

Meningiomas causing intracranial hemorrhage are rare, and hemorrhage from a lateral ventricular meningioma seems to be even rarer. We report a case of trigonal meningioma in a 43-year-old woman who presented with intraventricular hemorrhage, and describe the CT, MRI and angiographic findings.


Subject(s)
Adult , Female , Humans , Intracranial Hemorrhages/etiology , Lateral Ventricles/diagnostic imaging , Meningeal Neoplasms/complications , Meningioma/complications
14.
Neurol India ; 1999 Mar; 47(1): 40-2
Article in English | IMSEAR | ID: sea-120660

ABSTRACT

Movement disorders are uncommon presenting features of brain tumours. Early recognition of such lesions is important to arrest further deficit. We treated seven patients with movement disorders secondary to brain tumours over a period of seven years. Only two of these were intrinsic thalamic tumours (astrocytomas) while the rest were extrinsic tumours. The intrinsic tumours were accompanied by hemichorea. Among the extrinsic tumours, there was one pituitary macroadenoma with hemiballismus and four meningiomas with parkinsonism. Symptoms were unilateral in all patients except one with anterior third falcine meningioma who had bilateral rest tremors. There was relief in movement disorders observed after surgery. Imaging by computed tomography or magnetic resonance imaging is mandatory in the evaluation of movement disorders, especially if the presentation is atypical, unilateral and/or accompanied by long tract signs.


Subject(s)
Adenoma/complications , Adult , Aged , Astrocytoma/complications , Brain Neoplasms/complications , Chorea/etiology , Female , Humans , Male , Meningeal Neoplasms/complications , Meningioma/complications , Middle Aged , Parkinson Disease, Secondary/etiology , Pituitary Neoplasms/complications
15.
Article in English | WPRIM | ID: wpr-221952

ABSTRACT

A 62-year-old woman was evaluated for tinnitis and headache. Magnetic resonance imaging and angiography revealed the coexistence of a tentorial tumor encroaching the junction of the right transverse-sigmoid sinuses, and dural arteriovenous fistulous malformation (AVFM) of the right transverse sinus. AVFM was not manipulated at all during the surgery. The pathology was fibroblastic meningioma. Postoperatively, the dural AVFM completely disappeared on follow-up angiography. The fistulas were occluded also after surgery, even though there was no manipulation of the AVFM. It is suggested that the right dominant transverse-sigmoid sinuses are partially occluded by tentorial meningioma, developing the dural arteriovenous fistula of the right transverse sinus. An acquired origin of the dural AVFM was suggested in this case.


Subject(s)
Arteriovenous Malformations/diagnosis , Arteriovenous Malformations/complications , Carotid Artery, External/pathology , Carotid Artery, Internal/pathology , Cerebral Angiography , Dura Mater/pathology , Female , Humans , Jugular Veins/pathology , Magnetic Resonance Imaging , Meningeal Neoplasms/diagnosis , Meningeal Neoplasms/complications , Meningioma/diagnosis , Meningioma/complications , Middle Aged
19.
J Postgrad Med ; 1993 Oct-Dec; 39(4): 222-3
Article in English | IMSEAR | ID: sea-116663

ABSTRACT

A rare case of extracerebral dural cavernous angioma sited near the sigmoid sinus is reported. This 60 yr old male patient gave history of episodic ataxia of left sided limbs experienced twice on same day and occasional giddiness. Examination did not reveal any findings. A mass was diagnosed on CT Scan following which angiography was carried out. The features matched with those of a meningioma. Retro-sigmoid craniectomy was performed. Occipital artery was coagulated. Tumor was dissected out. Post-operative course of the patient was uneventful. Histopathology revealed that the mass was a cavernous haemangioma.


Subject(s)
Ataxia/etiology , Cerebral Angiography , Cranial Fossa, Posterior , Craniotomy/methods , Diagnosis, Differential , Dizziness/etiology , Dura Mater , Hemangioma, Cavernous/complications , Humans , Male , Meningeal Neoplasms/complications , Middle Aged , Tomography, X-Ray Computed
20.
Article in English | IMSEAR | ID: sea-44300

ABSTRACT

A case of hyperostosing meningioma en plaque at convexity of the cranial vault was presented. Reviewing the literature showed the rarity of this particular tumor. This is the first report in Thailand.


Subject(s)
Female , Frontal Bone/diagnostic imaging , Humans , Hyperostosis/complications , Meningeal Neoplasms/complications , Meningioma/complications , Middle Aged , Parietal Bone/diagnostic imaging
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