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1.
Acta cir. bras ; 30(6): 407-413, 06/2015. tab, graf
Article in English | LILACS | ID: lil-749649

ABSTRACT

PURPOSE: Vogt´s antioxidant solution (red blood cells, Ringer's solution, sodium bicarbonate, mannitol, allopurinol and 50% glucose) or its modification including hydroxyethyl starch (HES) were tested for the prevention of splanchnic artery occlusion shock. METHODS: Seventy rats were distributed in treatment (3), control (1), and sham (3) groups. Ischemia and reperfusion were induced by celiac, superior mesenteric and inferior mesenteric arteries occlusion for 40 min, followed by 60 min reperfusion or sham procedures. Controls received saline, both treatment and sham groups received the Vogt's solution, modified Vogt's solution (replacing Ringer's solution by HES), or HES. Mean arterial blood pressure (MABP), ileal malondialdehyde (MDA) and plasmatic MDA were determined, and a histologic grading system was used. RESULTS: At reperfusion, MABP dropped in all I/R groups. Only HES treatment was able to restore final MABP to the levels of sham groups. Plasmatic MDA did not show differences between groups. Ileum MDA was significantly higher in the control and treatment groups as compared to the sham group. Histology ranking was higher in the only in control group. CONCLUSIONS: Hydroxyethyl starch was able to prevent hemodynamic shock but not intestinal lesions. Both treatments with Vogt's solutions did not show any improvement. .


Subject(s)
Animals , Male , Hydroxyethyl Starch Derivatives/pharmacology , Mesenteric Arteries/drug effects , Mesenteric Vascular Occlusion/prevention & control , Plasma Substitutes/pharmacology , Reperfusion Injury/prevention & control , Disease Models, Animal , Hemodynamics/drug effects , Hydroxyethyl Starch Derivatives/therapeutic use , Ileum/blood supply , Ileum/pathology , Ischemia/prevention & control , Isotonic Solutions/pharmacology , Isotonic Solutions/therapeutic use , Malondialdehyde/analysis , Mesenteric Arteries/pathology , Mesenteric Vascular Occlusion/pathology , Plasma Substitutes/therapeutic use , Rats, Wistar , Reproducibility of Results , Splanchnic Circulation/drug effects , Time Factors , Treatment Outcome
2.
Rev. bras. cir. cardiovasc ; 29(4): 521-526, Oct-Dec/2014. tab, graf
Article in English | LILACS | ID: lil-741729

ABSTRACT

Introduction: Ischemic postconditioning has been recognized as effective in the prevention of reperfusion injury in situations of ischemia and reperfusion in various organs and tissues. However, it remains unclear what would be the best way to accomplish it, since studies show great variation in the method of their application. Objective: To assess the protective effect of ischemic postconditioning on ischemia and reperfusion in rats undergoing five alternating cycles of reperfusion and ischemia of 30 seconds each one. Methods: We studied 25 Wistar rats distributed in three groups: group A (10 rats), which underwent mesenteric ischemia (30 minutes) and reperfusion (60 minutes); Group B (10 rats), undergoing ischemia (30 minutes) and reperfusion (60 minutes), intercalated by postconditioning (5 alternating cycles of reperfusion and ischemia of 30 seconds each one); and group C - SHAM (5 rats), undergoing only laparotomy and manipulation of mesenteric artery. All animals underwent resection of an ileum segment for histological analysis. Results: The mean lesions degree according to Chiu et al. were: group A, 2.77, group B, 2.67 and group C, 0.12. There was no difference between groups A and B (P>0.05). Conclusion: Ischemic postconditioning was not able to minimize or prevent the intestinal tissue injury in rats undergoing ischemia and reperfusion process when used five cycles lasting 30 seconds each one. .


Introdução: O pós-condicionamento isquêmico tem sido reconhecido como eficaz na prevenção das lesões de reperfusão em situações de isquemia e reperfusão em vários órgãos e tecidos. Entretanto, não está ainda claro qual seria a melhor maneira de realizá-lo, já que as publicações mostram grande variação de método no seu emprego. Objetivo: Avaliar o efeito protetor do pós-condicionamento isquêmico na isquemia e reperfusão intestinal em ratos, através de cinco ciclos alternados de 30 segundos de isquemia e 30 segundos de reperfusão. Métodos: Foram estudados 25 ratos Wistar, distribuídos em três grupos: grupo A (10 ratos), em que se realizou isquemia (30 minutos) e reperfusão (60 minutos) mesentérica; grupo B (10 ratos), isquemia e reperfusão, seguidos de pós-condicionamento isquêmico com 5 ciclos alternados de reperfusão e reoclusão, de 30 segundos cada; e grupo C (5 ratos), controle (SHAM). Ao final, ressecou-se um segmento do intestino delgado para análise histológica. Avaliaram-se os resultados pela classificação de Chiu et al. e procedeu-se ao tratamento estatístico. Resultados: As médias dos graus de lesão tecidual segundo a classificação de Chiu et al. foram: no grupo A, 2,77; no grupo B, 2,67; e no grupo C, 0,12. A diferença entre o resultado do grupo A com o resultado do grupo B não teve significância estatística (P>0,05). Conclusão: O pós-condicionamento isquêmico não foi capaz de minimizar ou prevenir a lesão tecidual intestinal de ratos submetidos ao processo de isquemia e reperfusão mesentérica quando utilizados cinco ciclos com duração de 30 segundos cada. .


Subject(s)
Animals , Male , Intestines/blood supply , Ischemic Postconditioning/methods , Mesenteric Ischemia/prevention & control , Reperfusion Injury/prevention & control , Intestinal Mucosa/blood supply , Intestinal Mucosa/pathology , Intestines/pathology , Models, Animal , Mesenteric Arteries/pathology , Mesenteric Vascular Occlusion/pathology , Rats, Wistar , Reproducibility of Results , Severity of Illness Index , Time Factors
3.
Acta cir. bras ; 26(4): 285-288, July-Aug. 2011. ilus, tab
Article in English | LILACS | ID: lil-594348

ABSTRACT

PURPOSE: To evaluate the histopathology alterations of the intestinal mucosa of rabbits submitted to mesenteric artery ischemia and reperfusion with and without ischemic preconditioning. METHODS: Two groups of ten male New Zealand white rabbits body (weight 2.2-3.0, average 2.5 kg). For mesenteric ischemia induction in all animals the small bowel and mesentery were cut 30cm and 60cm far from the gastroduodenal pyloric transition before the proximal mesenteric artery occlusion. In the Group 1 animals, the proximal mesenteric artery was occluded for 45 min with an atraumatic vascular clamp, followed by reperfusion for 30 min. In the Group 2 the 45 min ischemic phase was preceded by three cycles of ischemia (2 minutes each) alternated with three cycles of reperfusion (2 minutes each). For istopathology study small bowel biopsies were obtained before ischemia (control), after 45 min of mesenteric ischemia and at 30 min. of mesenteric artery reperfusion. RESULTS: In the Group I animals, the followings histopathology grade results were observed: t1, mean 2,8; t2, mean 3,3. Using the Kruskal-Wallis non-parameter test, differences between t0 and t1 and t0 and t2 were significants (p<0.05), but not significant between t1 and t2 (p>0.05). In the Group 2 animals histopathology grade results were: t1 mean 2,6 and t2, mean 2,1. Differences between t0 and t1, t0 and t2 were significant (p<0.05). It was not observed differences (p>0.05) between results of t1 in both groups but histopathology injury observed in Group 1 t2 biopsies were higher (p<0.05) than observed in the same period (t2) of Group 2 animals. CONCLUSION: Microscopic examination of the biopsies revealed significant evidence of preconditioning protection against small bowel wall ischemia-reperfusion injury.


OBJETIVO: Avaliar as alterações histopatológicas da mucosa intestinal de coelhos submetidos a isquemia-reperfusão com e sem precondicionamento isquêmicol. MÉTODOS: Foram estudados dois grupos de dez coelhos Nova Zelândia machos com pesos variáveis entre 2,2 e 3,0 kg (média de 2,5 kg) de peso corpóreo. Para indução da isquemia, em todos os animais, o intestino delgado e o mesentério foram seccionados 30 cm e 60 cm após a transição pilórica gastroduodenal, antes da oclusão da artéria mesentérica cranial. Nos animais do Grupo 1, a artéria mesentérica proximal foi ocluida por pinçamento atraumático durante 45 min., seguido de reperfusão por 30 min. No Grupo 2, foi realizado precondicionamento por três ciclos de 2 min. de oclusão mesentérica intercalados com três ciclos de 2 min. de reperfusão, seguido de oclusão mantida por 45 min e reperfusão de 30min. como no Grupo I. Para estudo histopatológico, foram obtidas biópsias da parede intestinal antes da isquemia (t0-controle), após 45 min. de isquemia (t1) e após 30 min. de reperfusão (t2). RESULTADOS: No Grupo I foram observados os seguintes graus de lesões: t1, média de 2,8 e t2, média 3,3, Foram significantes as diferenças entre t0 e t1 e t0 e t2, mas não foram significantes as variações entre t1 e t2 (p>0,05). No Grupo 2, obteve-se em t1,média de 2,6 e t2, média 2,1. Foram significantes (p<0,05) as diferenças entre t0 e t1, t0 e t2 e entre t1 e t2. . Não ocorreu diferença significante (p>0,05) entre os resultados de t1 nos dois Grupos, mas foram significantes (p<0,05) as diferenças entre os resultados histopatológicos das biopsias de t2 dos Grupos 1 e 2. CONCLUSÃO: O precondicionamento isquêmico reduziu significantemente a degeneração histopatológica determinada pela reperfusão pós-isquêmica da parede intestinal.


Subject(s)
Animals , Male , Rabbits , Ischemic Preconditioning , Intestinal Mucosa/pathology , Reperfusion Injury/pathology , Biopsy , Case-Control Studies , Intestinal Diseases/pathology , Intestinal Diseases/prevention & control , Intestinal Mucosa/blood supply , Mesenteric Vascular Occlusion/pathology , Reperfusion Injury/prevention & control , Time Factors , Treatment Outcome
4.
Acta cir. bras ; 25(4): 318-321, July-Aug. 2010. ilus, graf, tab
Article in English | LILACS | ID: lil-553236

ABSTRACT

PURPOSE: To evaluate the histopathology alterations of the intestinal mucosa of rabbits submitted to different times of mesenteric artery ischemia and reperfusion with and without celiac artery collateral circulation supply. METHODS: Two groups of eight male New Zealand white rabbits (weight 2.2-3.5 kg) were used in this study. In the Group 1 animals, the proximal mesenteric artery was occluded for 60 min with an atraumatic vascular clamp, followed by reperfusion for 60 min. In the Group 2 animals the small bowel and mesentery were cut 30cm and 60cm far from the gastroduodenal pyloric transition before the proximal mesenteric artery occlusion. Small bowel biopsies were obtained before ischemia (control), after 30 min and 60 min of mesenteric ischemia and at 30 and 60 min. of mesenteric artery reperfusion. RESULTS: In the Group I animals, the followings histopathology grade results were observed: t1, mean 0.4 + 0.29; t2, mean 1.9 ± 0.38; t3, 1.9 ± 0.33; t4, 1.2 ± 0.36 and t5, 1.2 ± 0.32. Differences between t0 and t2 and between t3 and t4 were statistically significant (p<0.05). Differences between t2 and t3 and t4 and t5 were not significant (p>0.5). In the Group II animals, it was observed: t1, mean 1.6 ± 0.33; t2, 2.4 ± 0.36; t3, 3.0 ± 0.35; t4 3.4 ± 0.31; t5, 3 ± 031. Differences between t0 and t1, t1 and t2, and t2 and t3 were significant (p<0.05). Differences between histopathology grades results of samples t1 to t5 in Group 1 and 2 were statistically significant (p<0.5). CONCLUSION: Microscopic examination of the biopsies revealed significant evidence of worse small bowel wall ischemia-reperfusion lesions by exclusion of the celiac artery collateral circulation supply.


OBJETIVO: Avaliar as alterações histopatológicas da mucosa intestinal de coelhos submetidos à isquemia-reperfusão com e sem exclusão da circulação mesentérica colateral. MÉTODOS: Foram estudados dois grupos de oito coelhos Nova Zelândia machos com pesos variáveis entre 2,2 e 3,5 kg de peso corpóreo. Nos animais do Grupo 1, a artéria mesentérica proximal foi ocluida por pinçamento atraumático durante 60 min, seguido de reperfusão por 60 min. No Grupo 2 o intestino delgado e o mesentério foram seccionados 30 cm e 60 após a transição pilórica gastroduodenal antes da oclusão da artéria mesentérica cranial. Biópsias da parede intestinal foram obtidas antes da isquemia (controle), após 30 e 60 min. de isquemia. RESULTADOS: No Grupo I foram observados os seguintes graus de lesões: t1,média de 0.4 + 0.29; t2, média 1.9 ± 0.38; t3, 1.9 ± 0.33; t4, 1.2 ± 0.36 e t5, 1.2 ± 0.32. As diferenças entre t0 e t2 e entre t3 e t4 foram significantes (p<0.05). As diferenças entre t2 e t3 e t4 e t5 não foram significantes (p>0.5). No Group II observou-se: t1, média de 1.6 ± 0.33; t2, 2.4 ± 0.36; t3, 3.0 ± 0.35; t4 3.4 ± 0.31; t5, 3 ± 031. As diferenças entre t0 e t1, t1 e t2, e t2 e t3 foram significantes (p<0.05). As diferenças entre os resultados histopatológicos das biopsies de t1 a t5 dos Grupos 1 e 2 foram significantes (p<0.5). CONCLUSÃO: A exclusão da circulação mesentérica colateral agravou significantemente a degeneração histopatológica na isquemia-reperfusão da parede intestinal.


Subject(s)
Animals , Male , Rabbits , Collateral Circulation , Intestine, Small/blood supply , Mesenteric Arteries/physiology , Mesenteric Vascular Occlusion/pathology , Reperfusion Injury/pathology , Splanchnic Circulation/physiology , Intestinal Mucosa/pathology , Intestine, Small/pathology
5.
Rev. bras. cir. cardiovasc ; 24(2): 150-156, abr.-jun. 2009. ilus, tab, graf
Article in English, Portuguese | LILACS | ID: lil-525546

ABSTRACT

OBJETIVO: Avaliar o efeito do pré e pós-condicionamento isquêmico sobre a lesão tecidual na mucosa intestinal de ratos submetidos ao processo de isquemia e reperfusão mesentérica. MÉTODOS: Foram estudados 30 ratos Wistar, distribuídos em três grupos: grupo A, em que se realizou isquemia (30 minutos) e reperfusão (60 minutos) mesentérica; grupo B, isquemia e reperfusão mesentérica precedidos pelo pré-condicionamento isquêmico por três ciclos de isquemia e reperfusão com duração de dois minutos cada; grupo C, isquemia e reperfusão mesentérica e, precedendo o início da reperfusão, foi realizado o pós-condicionamento isquêmico por três ciclos de reperfusão e isquemia com duração de dois minutos cada. Ao final, ressecou-se um segmento do intestino delgado para análise histológica. Avaliaram-se os resultados pela classificação de Chiu et al. e procedeu-se ao tratamento estatístico. RESULTADOS: As médias dos graus de lesão tecidual segundo a classificação de Chiu et al. foram: no grupo A, 3,5; grupo B, 1,2; grupo C, 1. A diferença entre o resultado do grupo A com os resultados dos grupos B e C foi considerada estatisticamente significativa (P < 0,05). CONCLUSÃO: O pré e pós-condicionamento isquêmico foram capazes de minimizar, com intensidade semelhante, a lesão tecidual na mucosa intestinal de ratos submetidos ao processo de isquemia e reperfusão mesentérica.


OBJECTIVE: To assess the preconditioning and postconditioning effect on intestinal mucosal lesions in rats undergone mesenteric ischemia and reperfusion procedure. METHODS: Thirty Wistar rats were studied and divided into three groups: Group A, 10 rats undergone mesenteric ischemia (30 minutes) and reperfusion (60 minutes); Group B, 10 rats undergone mesenteric ischemia and reperfusion preceded by ischemic preconditioning for three cycles of ischemia and reperfusion for two minutes each; Group C, 10 rats undergone mesenteric ischemia and reperfusion and, preceding the beginning of reperfusion, ischemic postconditioning was performed for three cycles of reperfusion and ischemia for two minutes each. Then, a segment of small intestine was resected for histological analysis. We assessed the results by Chiu et al. score and the statistical analysis was performed. RESULTS: According to Chiu et al. score, the means of lesion degree were: In the group A, 3.5; Group B, 1.2; Group C, 1. The difference between group A with the groups B and C was considered statistically significant (P < 0.05). CONCLUSION: Ischemic pre- and postconditioning were capable of minimizing - in a similar intensity - the tissue injury on the intestinal mucosa of rats undergone mesenteric ischemia and reperfusion process.


Subject(s)
Animals , Male , Rats , Ischemic Preconditioning , Ileum/blood supply , Intestinal Mucosa/blood supply , Mesenteric Arteries , Reperfusion Injury/prevention & control , Ileum/pathology , Intestinal Mucosa/pathology , Ischemic Preconditioning/adverse effects , Models, Animal , Mesenteric Vascular Occlusion/pathology , Rats, Wistar , Reperfusion Injury/pathology , Statistics, Nonparametric
6.
Braz. j. med. biol. res ; 41(7): 634-639, July 2008. tab
Article in English | LILACS | ID: lil-489524

ABSTRACT

The type of fluid used during resuscitation may have an important impact on tissue edema. We evaluated the impact of two different regimens of fluid resuscitation on hemodynamics and on lung and intestinal edema during splanchnic hypoperfusion in rabbits. The study included 16 female New Zealand rabbits (2.9 to 3.3 kg body weight, aged 8 to 12 months) with splanchnic ischemia induced by ligation of the superior mesenteric artery. The animals were randomized into two experimental groups: group I (N = 9) received 12 mL·kg-1·h-1 lactated Ringer solution and 20 mL/kg 6 percent hydroxyethyl starch solution; group II (N = 7) received 36 mL·kg-1·h-1 lactated Ringer solution and 20 mL/kg 0.9 percent saline. A segment from the ileum was isolated to be perfused. A tonometric catheter was placed in a second gut segment. Superior mesenteric artery (Q SMA) and aortic (Qaorta) flows were measured using ultrasonic flow probes. After 4 h of fluid resuscitation, tissue specimens were immediately removed for estimations of gut and lung edema. There were no differences in global and regional perfusion variables, lung wet-to-dry weight ratios and oxygenation indices between groups. Gut wet-to-dry weight ratio was significantly lower in the crystalloid/colloid-treated group (4.9 ± 1.5) than in the crystalloid-treated group (7.3 ± 2.4) (P < 0.05). In this model of intestinal ischemia, fluid resuscitation with crystalloids caused more gut edema than a combination of crystalloids and colloids.


Subject(s)
Animals , Female , Rabbits , Edema/etiology , Hydroxyethyl Starch Derivatives/administration & dosage , Ischemia/therapy , Isotonic Solutions/administration & dosage , Mesenteric Vascular Occlusion/therapy , Resuscitation/methods , Disease Models, Animal , Edema/pathology , Hydroxyethyl Starch Derivatives/adverse effects , Intestinal Diseases/etiology , Intestinal Diseases/pathology , Intestinal Mucosa/blood supply , Intestinal Mucosa/pathology , Ischemia/pathology , Isotonic Solutions/adverse effects , Lung Diseases/etiology , Lung Diseases/pathology , Mesenteric Vascular Occlusion/pathology , Random Allocation , Resuscitation/adverse effects , Severity of Illness Index , Splanchnic Circulation
7.
Acta cir. bras ; 23(1): 22-28, Jan.-Feb. 2008. ilus, graf
Article in English | LILACS | ID: lil-474136

ABSTRACT

PURPOSE: To evaluate the effect of the ischemic preconditioning and the ischemic postconditioning over the tissue injury in the intestinal mucosa of rats undergoing the procedure of mesenteric ischemia and reperfusion. METHODS: Thirty Wistar rats were studied, divided in three groups: group A, undergoing mesenteric ischemia (30 minutes) and reperfusion (60 minutes); group B, mesenteric ischemia and reperfusion preceded by ischemic preconditioning; group C, mesenteric ischemia and reperfusion and, before the beginning of reperfusion, the ischemic postconditioning was performed. At the end, a segment of the small intestine was dissected for histological analysis. The results were evaluated using the CHIU et al.6 classification followed by the statistic treatment. RESULTS: The mean values of the tissue injury levels were: group A, 3.5; group B, 1.2; and group C, 1. The difference between the result of group A with the results of groups B and C was considered statistically significant (p < 0,05). CONCLUSION: The ischemic preconditioning and postconditioning are able to minimize the tissue injury in the intestines of rats that underwent the procedure of mesenteric ischemia and reperfusion.


OBJETIVO: Avaliar o efeito do pré e pós-condicionamento isquêmico sobre a lesão tecidual na mucosa intestinal de ratos submetidos ao processo de isquemia e reperfusão mesentérica. MÉTODOS: Foram estudados 30 ratos Wistar, distribuídos em três grupos: grupo A, em que se realizou isquemia (30 minutos) e reperfusão (60 minutos) mesentérica; grupo B, isquemia e reperfusão mesentérica precedidos pelo pré-condicionamento isquêmico; grupo C, isquemia e reperfusão mesentérica e, precedendo o início da reperfusão, foi realizado o pós-condicionamento isquêmico. Ao final, ressecou-se um segmento do intestino delgado para análise histológica. Avaliaram-se os resultados pela classificação de CHIU e col.6 e procedeu-se o tratamento estatístico. RESULTADOS: As médias dos graus de lesão tecidual foram: grupo A, 3,5; grupo B, 1,2; grupo C, 1. A diferença entre o resultado do grupo A com os resultados dos grupos B e C foi considerada estatisticamente significativa (p < 0,05). CONCLUSÃO: O pré e pós-condicionamento isquêmico foram capazes de minimizar a lesão tecidual na mucosa intestinal de ratos submetidos ao processo de isquemia e reperfusão mesentérica.


Subject(s)
Animals , Male , Rats , Intestinal Mucosa/blood supply , Intestine, Small/blood supply , Ischemic Preconditioning/methods , Mesenteric Vascular Occlusion/prevention & control , Reperfusion Injury/prevention & control , Disease Models, Animal , Intestinal Mucosa/pathology , Intestine, Small/pathology , Mesenteric Artery, Superior , Mesenteric Vascular Occlusion/pathology , Rats, Wistar , Reperfusion Injury/pathology , Statistics, Nonparametric
8.
Article in English | IMSEAR | ID: sea-65477

ABSTRACT

BACKGROUND: Involvement of mesenteric vessels in intestinal tuberculosis and its role in the pathogenesis of the intestinal changes have not been studied histologically. AIM: To study mesenteric vessels in patients undergoing surgery for complications of intestinal tuberculosis. METHODS: Resected intestinal specimens from 68 patients presenting with intestinal perforation and intestinal obstruction were examined; involvement of the major mesenteric vessels was evaluated. RESULTS: Granulomas were seen in the vessel wall in one case and near the vessel wall in 11 cases, intraluminal thrombi were seen in 23 cases, and subintimal fibrosis in nine cases. Perivascular cuffing was seen in intramural and subserosal vessels in ten cases. CONCLUSIONS: Changes in the vessel wall may lead to gut ischemia, which may contribute to the development of strictures and stercoral perforation in intestinal tuberculosis.


Subject(s)
Adolescent , Adult , Child , Female , Humans , Intestines/blood supply , Ischemia/pathology , Male , Mesenteric Arteries/pathology , Mesenteric Vascular Occlusion/pathology , Middle Aged , Thrombosis/pathology , Tuberculosis, Gastrointestinal/pathology
9.
Ginecol. obstet. Méx ; 61(11): 323-5, nov. 1993. ilus
Article in Spanish | LILACS | ID: lil-134847

ABSTRACT

Se presentan dos casos de TVM en pacientes puérperas. Se hace hincapie en las condiciones favorables para esta patología en este periodo. Se revisa en la literatura su etiología, incidencia, presentación clínica y estudios paraclínicos de utilidad para su diagnóstico. Su tratamiento dependerá de la evolución y si se hace o no el diagnóstico preoperatorio. Si esto se logra, el manejo deberá ser conservado a base de terapia trombolítica y anticoagulante. Si la paciente no responde favorablemente a este tratamiento o presenta datos de irritación peritoneal y/o sepsis, deberá operarse y efectuar las maniobras que dicten los hallazgos quirúrgicos. Con ayuda de la anticoagulación los resultados en cuanto a mortalidad y recurrencia han mejorado. Se insiste en sospechar TVM en pacientes puérperas con un cuadro obstructivo no explicado por otras causas y solicitar ultrasonido, TAC o arteriografía selectiva


Subject(s)
Humans , Female , Adult , Mesenteric Vascular Occlusion/physiopathology , Postpartum Period , Thrombosis/physiopathology , Mesenteric Veins/physiopathology , Mesenteric Vascular Occlusion/pathology , Mesenteric Veins/pathology
10.
Arq. bras. med ; 66(3): 241-7, maio-jun. 1992. ilus
Article in Portuguese | LILACS | ID: lil-123589

ABSTRACT

O autor faz uma análise de cinco pacientes com doença de Mondor e julga os elementos que representam um papel predominante dentro do contexto atual desta forma de enfermidade. Traça as suas principais características clínico-patológicas. Conclui estipulando as condutas de ordem terapêutica inerente a este processo patológico


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Mesenteric Vascular Occlusion/pathology , Penis/pathology , Thrombophlebitis/physiopathology , Thrombosis/physiopathology , Mesenteric Veins/surgery , Erectile Dysfunction/psychology , Sinus Thrombosis, Intracranial/pathology
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