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1.
Rev. Paul. Pediatr. (Ed. Port., Online) ; 37(3): 332-337, July-Sept. 2019. tab, graf
Article in English | LILACS (Americas) | ID: biblio-1041344

ABSTRACT

ABSTRACT Objective: To investigate the difference in the proportion of students with metabolic syndrome, diagnosed according to different criteria. Methods: The sample consisted of 241 students (136 boys and 105 girls) aged 10 to 14 years, from public and private schools in Paranavaí, Paraná. We used three distinct diagnostic criteria for metabolic syndrome, considering the presence of at least three of the following risk factors: increased waist circumference, hypertension, fasting hyperglycemia, low HDL-C, and elevated triglycerides. Results: The prevalence of metabolic syndrome found was 1.7% (confidence interval of 95% - 95%CI 0-3.3) for the IDF criterion; 3.3% (95%CI 1.0-5.6) for Cook; and 17.4% (95%CI 12.6-22.3) for Ferranti. Analyzing the criteria in pairs, the agreement between IDF and Cook was 97.5% (k=0.95); between IDF and Ferranti, 83.4% (k=0.67); and between Cook and Ferranti, 85.9% (k=0.72). Onlyone student (0.4%) was diagnosed with metabolic syndrome solely by the IDF criterion, while 34 (14.1%) were diagnosed exclusively by Ferranti. The comparison of the three criteria showed that Ferranti presented the highest proportion of metabolic syndrome (p<0.001), and Cook had a greater proportion than IDF (p<0.001). Conclusions: We found a significant difference in the proportion of metabolic syndrome in the three criteria. The choice of which criterion to use can compromise not only the percentage of metabolic syndrome prevalence but also interfere in strategies of intervention and prevention in children and adolescents with and without metabolic syndrome, respectively.


RESUMO Objetivo: Investigar a diferença na proporção de escolares com síndrome metabólica diagnosticada segundo diferentes critérios. Métodos: Duzentos e quarenta e um escolares (136 meninos e 105meninas), com idade entre dez e 14 anos, das redes pública e privada de Paranavaí, Paraná. Foram utilizados três diferentes critérios para o diagnóstico da síndrome metabólica, considerando a presença de, ao menos, três dos seguintes fatores de risco: circunferência de cintura aumentada, hipertensão arterial, hiperglicemia em jejum, baixo nível de HDL-C e triglicerídeos elevado. Resultados: A prevalência de síndrome metabólica encontrada foi de 1,7% (intervalo de confiança de 95% - IC95% 0-3,3), para o critério de IDF; 3,3% (IC95% 1,0-5,6) em Cook; e 17,4% (IC95% 12,6-22,3) em Ferranti. Na verificação dos critérios em pares, a concordância entre IDF e Cook foi de 97,5% (k=0,95); entre IDF e Ferranti, 83,4% (k=0,67); e entre Cook e Ferranti, 85,9% (k=0,72). Em apenas um aluno (0,4%) a síndrome metabólica foi diagnosticada exclusivamente pelo critério de IDF, e em 34 alunos (14,1%), pelo critério de Ferranti. A comparação entre os três critérios mostrou que o de Ferranti apresentou maior proporção de síndrome metabólica que os demais (p<0,001), e o de Cook maior proporção em relação ao da IDF (p<0,001). Conclusões: Houve diferença significante na proporção de síndrome metabólica nos três critérios. A escolha do critério a ser utilizado pode comprometer não apenas o percentual de prevalência de síndrome metabólica, mas também atrapalhar as estratégias de prevenção e intervenção em crianças e adolescentes com e sem síndrome metabólica, respectivamente.


Subject(s)
Humans , Male , Female , Child , Adolescent , Metabolic Syndrome/epidemiology , Triglycerides/blood , Brazil/epidemiology , Glycated Hemoglobin A/metabolism , Biomarkers/blood , Prevalence , Cross-Sectional Studies , Risk Factors , Metabolic Syndrome/diagnosis , Waist Circumference/physiology
2.
Rev. medica electron ; 41(3): 628-640, mayo.-jun. 2019. tab
Article in Spanish | LILACS (Americas) | ID: biblio-1094072

ABSTRACT

RESUMEN Introducción: la prevalencia del síndrome metabólico, a nivel mundial, es muy elevada y continúa en aumento vertiginosamente en los últimos años. Por lo que se puede considerar una pandemia de la época contemporánea, se estima que el 25 % de la población adulta la padece. Objetivo: determinar la prevalencia del síndrome metabólico e identificar otras formas clínicas de enfermedad vascular ateroesclerótica, en gerontes hospitalizados en Servicios de Geriatría del Hospital Provincial Clínico Quirúrgico Docente "Celia Sánchez Manduley", Manzanillo, Granma; en el período comprendido entre junio 2015 a junio 2016. Materiales y métodos: se realizó estudio observacional, descriptivo, de corte transversal. Se incluyeron los 120 senescentes que ingresaron en los Servicios de Geriatría. Resultados: se estableció el diagnóstico de síndrome metabólico en 105 individuos de 120 sujetos estudiados. El grupo de 70-79 años de edad y el sexo masculino fueron los más afectados por la endocrinopatía. Las otras formas clínicas de enfermedad vascular ateroesclerótica que se identificaron en los senescentes estudiados, fueron: cardiopatía isquémica, enfermedad cerebrovascular y cardiopatía hipertensiva. Conclusiones: existe una alta prevalencia del síndrome metabólico en los adultos mayores estudiados.


ABSTRACT Introduction: the prevalence of the metabolic syndrome is very high around the world and is still vertiginously increasing in the last years. Therefore, it can be considered a pandemic of the current times. It is thought that 25 % of the adult population suffers it. Objective: to determine the prevalence of the metabolic syndrome and to identify other clinical forms of the atherosclerotic vascular disease in elder people who entered the Service of Geriatrics of the Provincial Teaching Clinical Surgical Hospital "Celia Sanchez Manduley", of Manzanillo, Granma, in the period from June 2015 to June 2016. Materials and methods: a cross-sectional, observational, descriptive study was carried out with the inclusion of the 120 elder people who the Service of Geriatrics. Results: 105 individuals of 129 studied were diagnosed with metabolic syndrome. The 79-79 age group and male sex were the most affected by endocrinopathy. Other clinical forms of the arteriosclerotic vascular disease identified in the studied elder people were ischemic heart disease, cerebrovascular disease and hypertensive heart disease. Conclusions: there is a high prevalence of the metabolic syndrome among the studied elder people.


Subject(s)
Humans , Aged , Aging , Cerebrovascular Disorders/diagnosis , Risk Factors , Myocardial Ischemia/diagnosis , Metabolic Syndrome/diagnosis , Metabolic Syndrome/etiology , Metabolic Syndrome/prevention & control , Metabolic Syndrome/therapy , Metabolic Syndrome/epidemiology , Diabetes Mellitus, Type 2/diagnosis , Geriatrics , Epidemiology, Descriptive , Cross-Sectional Studies , Hospital Care , Obesity, Abdominal/diagnosis , Early Medical Intervention , Observational Study , Hypertension/diagnosis
3.
J. pediatr. (Rio J.) ; 95(3): 291-297, May-June 2019. tab
Article in English | LILACS (Americas) | ID: biblio-1012606

ABSTRACT

Abstract Objective: To assess the prevalence of metabolic syndrome-like symptoms in a population of preterm infants with very low birth weight (<1500 g) at 2 years of corrected age and identify the occurrence of associated risk factors. Methods: Cross-sectional study during a five-year period, including preterm infants born with very low birth weight evaluated at 2 years of corrected age. Metabolic syndrome-like symptoms was defined by the presence of three or more of these criteria: abdominal circumference ≥ 90th percentile, fasting blood glucose ≥ 100 mg/dL, triglycerides ≥ 110 mg/dL, HDL cholesterol ≤ 40 mg/dL, and blood pressure ≥ 90th percentile. Results: A total of 214 preterm infants with birth weight < 1500 g were evaluated. The prevalence of metabolic syndrome-like symptoms at 2 years of corrected age was 15.1%. Arterial hypertension was present in 57.5%, HDL ≤ 40 mg/dL in 29.2%, hypertriglyceridemia in 22.6%, and abdominal circumference above the 90th percentile in 18.8%. Only 3.7% had hyperglycemia. The presence of periventricular leukomalacia was an independent risk factor for arterial hypertension at this age (OR 2.34, 95% CI: 0.079-0.69, p = 0.008). Overweight and obesity at 2 years of corrected age were independently associated with metabolic syndrome-like symptoms (OR 2.75, 95% CI: 1.19-6.36, p = 0.018). Conclusion: Metabolic syndrome-like symptoms can be observed in very low birth weight preterm infants as early as 2 years of corrected age. Overweight and early-onset obesity are significant risk factors for metabolic syndrome-like symptoms, which deserves appropriate intervention for this high-risk population.


Resumo Objetivo: Avaliar a prevalência de síndrome metabólica "like" em população de crianças prematuras com muito baixo peso de nascimento (< 1500 gramas) aos dois anos de idade corrigida e identificar a ocorrência de fatores de risco associados. Métodos: Estudo transversal que incluiu prematuros nascidos durante um período de cinco anos com muito baixo peso de nascimento, avaliados aos dois anos de idade corrigida. A síndrome metabólica "like" foi definida pela presença de três ou mais desses critérios: circunferência abdominal ≥ percentil 90, glicemia de jejum ≥ 100 mg/dL, triglicerídeos ≥ 110 mg/dL, colesterol HDL ≤ 40 mg/dL e pressão arterial ≥ percentil 90. Resultados: Foram avaliados 214 prematuros abaixo de 1.500 gramas. A prevalência de síndrome metabólica "like" aos dois anos de idade corrigida foi 15,1%. Hipertensão arterial esteve presente em 57,5%, HDL ≤ 40 mg/dL em 29,2%, hipertrigliceridemia em 22,6% e aumento da circunferência abdominal acima do percentil 90 em 18,8%. Apenas 3,7% apresentaram hiperglicemia. A presença de leucomalácia periventricular foi um fator de risco independente para hipertensão arterial nessa idade (OR 2,34; IC 95% 0,079-0,69; p = 0,008); sobrepeso e obesidade aos dois anos de idade corrigida foram independentemente associados com síndrome metabólica "like" (OR 2,75, IC 95% CI 1,19-6,36; p = 0,018). Conclusão: Síndrome metabólica "like" ocorre em prematuros de muito baixo peso tão precocemente quanto dois anos de idade corrigida. Sobrepeso e obesidade de início precoce são fatores de risco significativos para síndrome metabólica "like", merecem intervenção apropriada para essa população de alto risco.


Subject(s)
Humans , Infant, Newborn , Child, Preschool , Infant, Premature , Infant, Very Low Birth Weight , Metabolic Syndrome/epidemiology , Brazil/epidemiology , Prevalence , Cross-Sectional Studies , Risk Factors , Follow-Up Studies
4.
Rev. bras. psiquiatr ; 41(1): 38-43, Jan.-Mar. 2019. tab
Article in English | LILACS (Americas) | ID: biblio-985355

ABSTRACT

Objective: To identify the association of metabolic syndrome (MetS) and psychiatric disorders in young adults in southern Brazil. Methods: This population based cross-sectional study involved a total of 1,023 young adults between the ages of 21 and 32 years. Current episodes of psychiatric disorders were assessed using the Mini International Neuropsychiatric Interview - Plus version. MetS was evaluated using the National Cholesterol Education Program Adult Treatment Panel III (NCEP/ATP III). Results: Of the 1,023 participants, 24.3% were identified with MetS, 13.5% were diagnosed with anxiety disorders, 7.5% with current depression, 3.9% with bipolar disorders and 10.1% were at risk of suicide. MetS was associated with ethnicity (p = 0.022), excess weight (p < 0.001), current anxiety disorders (p < 0.001), current mood disorders (bipolar disorder in mood episode and current depression) (p < 0.001), and suicide risk (p < 0.001). Conclusions: MetS was associated with psychiatric disorders. Awareness of factors associated with MetS can help identify high-risk individuals and stimulate disease prevention and control programs, as well as lifestyle changes.


Subject(s)
Humans , Female , Adult , Young Adult , Metabolic Syndrome/complications , Mental Disorders/psychology , Socioeconomic Factors , Brazil/epidemiology , Prevalence , Cross-Sectional Studies , Metabolic Syndrome/psychology , Metabolic Syndrome/epidemiology , Mental Disorders/epidemiology
5.
In. Negrão, Carlos Eduardo; Pereira-Barretto, Antônio Carlos; Rondon, Maria Urbana Pinto Brandão. Cardiologia do exercício: do atleta ao cardiopata / Exercise cardiology: from athlete to heart disease. São Paulo, Manole, 4ª; 2019. p.305-334.
Monography in Portuguese | LILACS (Americas) | ID: biblio-1015677
6.
Rev. cuba. endocrinol ; 29(3): 1-11, set.-dic. 2018. tab
Article in Spanish | LILACS (Americas) | ID: biblio-978393

ABSTRACT

Introducción: El síndrome de ovario poliquístico es el trastorno ovulatorio más frecuente en la mujer de edad reproductiva. Se asocia a trastornos metabólicos que pudieran tener relación con el hiperandrogenismo. Objetivo: Identificar los trastornos metabólicos en mujeres portadoras de síndrome de ovario poliquístico y su relación con el hiperandrogenismo. Métodos: Se realizó un estudio transversal, descriptivo, de diciembre 2016 a junio 2017 en el Centro de Reproducción Asistida de Baja Tecnología de Matanzas. Fueron incluidas todas las mujeres que asistieron a la consulta de infertilidad, que cumplieran los criterios de Rotterdam para el diagnóstico de síndrome de ovario poliquístico (n = 38). Se recolectaron los datos generales, antecedentes patológicos personales y examen físico. Se realizó prueba de tolerancia a la glucosa, se determinaron los valores de hormona folículo estimulante, hormona luteinizante, prolactina, testosterona, insulina, glucemia, hemoglobina glucosilada, triglicéridos, colesterol total, colesterol de lipoproteína de alta densidad, creatinina y ácido úrico. Se calculó el HOMA-IR y se identificaron las portadoras de síndrome metabólico. Para el análisis estadístico se crearon 2 grupos: uno con hiperandrogenismo (n = 17) y otro sin hiperandrogenismo (n = 21). Resultados: Los trastornos metabólicos fueron frecuentes en toda la serie. Las pacientes con hiperandrogenismo tuvieron mayor frecuencia de obesidad (82,4 por ciento; p = 0,013), circunferencia abdominal ≥ 88 cm (94,1 por ciento; p = 0,005), tolerancia a la glucosa alterada (41,2 por ciento; p = 0,001) e hiperuricemia (17,6 por ciento; p = 0,045). Conclusiones: Los trastornos metabólicos fueron frecuentes en este grupo de pacientes. Las portadoras de hiperandrogenismo tuvieron trastornos metabólicos más marcados que las no hiperandrogénicas, sobre todo tolerancia a la glucosa alterada e hiperuricemia, probablemente mediados por la obesidad(AU)


Introduction: Polycystic ovary syndrome is the most common ovulatory disorder among women of childbearing age. It is associated to metabolic disorders which might in turn be related to hyperandrogenism. Objective: Identify the metabolic disorders among women with polycystic ovary syndrome and their relationship to hyperandrogenism. Methods: A cross-sectional descriptive study was conducted at the Low-Technology Assisted Reproduction Center in Matanzas from December 2016 to June 2017. The study included all the women attending infertility consultation who met the Rotterdam criteria for polycystic ovary syndrome diagnosis (n = 38). General data and information on personal pathological antecedents were collected and physical examination performed. The glucose tolerance test was applied and determination was made of values for follicle-stimulating hormone, luteinizing hormone, prolactin, testosterone, insulin, glycemia, glycated hemoglobin, triglycerides, total cholesterol, high-density lipoprotein cholesterol, creatinine and uric acid. HOMA-IR was estimated and metabolic syndrome carriers were identified. Two groups were formed for statistical analysis: one with hyperandrogenism (n = 17) and one without hyperandrogenism (n = 21). Results: Metabolic disorders were common across the series. Patients with hyperandrogenism had a higher frequency of obesity (82.4 percent; p = 0.013), waist circumference ? 88 cm (94.1 percent; p = 0.005), impaired glucose tolerance (41.2 percent; p = 0.001) and hyperuricemia (17.6 percent; p = 0.045). Conclusions: Metabolic disorders were common in this group of patients. Hyperandrogenism carriers had more marked metabolic disorders than non-carriers, particularly as concerns impaired glucose tolerance and hyperuricemia, probably mediated by obesity(AU)


Subject(s)
Humans , Female , Adult , Polycystic Ovary Syndrome/diagnosis , Data Collection/statistics & numerical data , Hyperandrogenism/epidemiology , Metabolic Syndrome/epidemiology , Obesity/diet therapy , Epidemiology, Descriptive , Cross-Sectional Studies , Statistical Analysis
7.
Rev. salud pública ; 20(6): 742-747, nov.-dic. 2018. tab
Article in Portuguese | LILACS (Americas) | ID: biblio-1020853

ABSTRACT

RESUMO Objetivo Analisar a prevalência de Síndrome Metabólica entre os usuários do programa hipertensão e diabetes de um Centro de Saúde da cidade de Jequié, Bahia, Brasil. Métodos Trata-se de um estudo descritivo de corte transversal, realizado na cidade de Jequié Bahia. Os participantes da pesquisa foram usuários do programa HIPERDIA do Centro de Saúde inserida na atenção primária. Resultados A prevalência de Síndrome Metabólica nesses usuários foi de 43%. Quanto ao gênero, a prevalência foi de 35% entre homens e 47% em mulheres, considerando que em 23% dos prontuários não havia dados suficientes para a classificação. Conclusão Evidenciou-se que a síndrome metabólica atinge proporcionalmente mais as mulheres do que os homens, ao passo que em relação à idade foi verificado maior prevalência da doença em indivíduos maiores de 60 anos.(AU)


ABSTRACT Objective To identify the prevalence of metabolic syndrome in users of the hypertension and diabetes mellitus program at a Health Center in Jequié City, Bahia, Brazil. Materials and methods This is a descriptive cross-sectional study. The sample consisted of 100 patients enrolled in HIPERDIA. This study was approved by the Research Ethics Committee of the State University of Southwest of Bahia (Minutes no. 013/2011). Results The prevalence of metabolic syndrome in these users was 43%. Regarding sex, the prevalence was 35% among men and 47% among women, considering that in 23% of the medical records there were insufficient data for classification. Conclusions It was evidenced that the metabolic syndrome reaches proportionately more women than men, whereas, in relation to age, a higher prevalence of the disease was verified in individuals older than 60 years.(AU)


RESUMEN Objetivo Analizar la prevalencia de síndrome metabólico entre los usuarios del programa hipertensión y diabetes de un Centro de Salud de la ciudad de Jequié, Bahia, Brasil. Método Se trata de un estudio descriptivo de corte transversal. La muestra fue constituida por 100 pacientes registrados en HIPERDIA. Este estudio fue aprobado por el Comité de Ética en Investigación de la Universidad Estadual del Sudoeste de Bahía (Dictamen n ° 013/2011). Resultados La prevalencia de síndrome metabólico en estos usuarios fue del 43%. En cuanto al género, la prevalen-cia fue del 35% entre hombres y el 47% en mujeres, considerando que en el 23% de los prontuarios no había datos suficientes para la clasificación. Conclusión Se evidenció que el síndrome metabólico alcanza proporcionalmente más a las mujeres que los hombres, mientras que en relación a la edad se verificó mayor prevalencia de la enfermedad en individuos mayores de 60 años.(AU)


Subject(s)
Humans , Primary Health Care , Cardiovascular Diseases/etiology , Metabolic Syndrome/epidemiology , Diabetes Mellitus/etiology , Hypertension/etiology , Obesity/etiology , Brazil/epidemiology , Epidemiology, Descriptive , Cross-Sectional Studies/instrumentation
8.
Int. j. cardiovasc. sci. (Impr.) ; 31(6): 594-602, nov.- dez. 2018. tab, graf
Article in English | LILACS (Americas) | ID: biblio-979844

ABSTRACT

Background: Cardiovascular disease is the leading cause of mortality in the world and physical inactivity represents an important risk factor. Objective: This study aimed to evaluate the prevalence of physical inactivity in the adult population and its effects on blood pressure, blood glucose and lipid profile. Methods: A population-based cross-sectional study with stratified simple random sampling was conducted in 1,717 adults divided by age groups: 18-39, 40-49, 50-59, 60-69 and ≥ 70 years. The participants answered the physical activity questionnaire and were classified as physically active or inactive. The bootstrap statistical method was used to assess physical activity, associated with lipid profile and blood glucose levels. The level of significance was 5%. Results:The prevalence of physical inactivity in the general population was 65.8%. There was a significant difference in the group older than 70 years. There was a significant decrease in physical activity in the group with lower educational level, with a significant difference between social classes AB and C. The prevalence of hypertension was 27.5% among physically inactive and 21.4% among active individuals (p = 0.04). The prevalence of metabolic syndrome was 26.1% in inactive and 16.7% in the active individuals (p = 0.007). Total cholesterol, low-density lipoprotein and triglycerides levels were more elevated in the physically inactive group, which was not observed with high-density lipoprotein levels. Blood glucose was also higher in the inactive group. Conclusion: This study shows a high prevalence of physical inactivity and a positive correlation between risk factors for cardiovascular disease, mainly blood pressure, glucose and lipids profiles


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Blood Pressure , Exercise , Prevalence , Metabolic Syndrome/epidemiology , Coronary Artery Disease , Brazil , Cardiovascular Diseases/mortality , Chronic Disease , Statistical Analysis , Risk Factors , Risk Assessment , Diabetes Mellitus , Sedentary Behavior , Hypertension , Cholesterol, HDL
9.
Int. j. cardiovasc. sci. (Impr.) ; 31(6): 603-609, nov.- dez. 2018. tab, ilus
Article in English | LILACS (Americas) | ID: biblio-979878

ABSTRACT

Background: No previous study has evaluated the prevalence of metabolic syndrome (MS) in more than one region in Venezuela.Objective: To determine the prevalence of MS in three Venezuelan regions. Methods: From 2006 to 2010, a total of 1,320 subjects aged ≥ 20 years were selected by multistage stratified random sampling from the regions of Lara State (western region), Mérida State (the Andean region), and Capital District (Capital Region). Anthropometric measurements, blood pressure, and biochemical analysis were obtained from each participant. MS was defined according to the harmonized Joint Interim Statement (2009) definition.Results: Mean age was 44.8 ± 0.39 years and 68.5% of the participants were female. The overall prevalence of MS was 35.7% (95% confidence interval 32.2 ­ 39.2%), while the prevalence was 42.5% (95% CI 38.8 ­ 46.1%) among men and 32.6% (95% CI 29.1 ­ 36.0%) among women (p < 0.001). In women, the prevalence of MS increased at almost every decade of life, while in men, the prevalence was similar from the age of 30 years onwards. The most prevalent abnormalities were low HDL-c levels (58.6%, 95% CI 54.9 ­ 62.1%), abdominal obesity (52.0%, 95% CI 48.4 ­ 55.7%), and elevated triglycerides levels (39.7%, 95% CI 36.1 ­ 43.2%). The prevalence of MS increased with increasing body mass index categories. Conclusion: In Venezuela, MS is a highly prevalent condition, which increases the risk of type 2 diabetes and cardiovascular disease in a large number of subjects


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Venezuela/epidemiology , Prevalence , Metabolic Syndrome/epidemiology , Blood Pressure , Cardiovascular Diseases , Sex Factors , Statistical Analysis , Risk Factors , Diabetes Mellitus , Dyslipidemias , Obesity, Abdominal , Observational Study , Hypercholesterolemia , Cholesterol, HDL
10.
Rev. cuba. endocrinol ; 29(2): 1-16, mayo.-ago. 2018. ilus, tab
Article in Spanish | LILACS (Americas) | ID: biblio-978386

ABSTRACT

Introducción: el índice cintura/cadera se presenta como un elemento más de la valoración clínica de la obesidad y sus consecuencias. Objetivo: describir la utilidad del empleo del índice cintura/cadera en la detección del riesgo cardiometabólico. Métodos: se utilizó Google Académico como motor de búsqueda y se obtuvo un total de 97 artículos, de los cuales 61 fueron referenciados por cumplir con el objetivo enunciado. Resultados: la obesidad se comporta como una enfermedad multifactorial, de evolución crónica, con importantes consecuencias para la salud. El incremento del tejido adiposo abdominal, propicia una mayor síntesis y liberación de adipoquinas y otras sustancias, que pueden deteriorar el metabolismo lipídico y glucídico a través del aumento de la resistencia a la insulina, e incrementan el riesgo cardiovascular. El índice cintura/cadera evalúa de forma indirecta la grasa abdominal. Es un indicador poco costoso, sencillo de aplicar y fácil de interpretar en los 3 niveles de atención de salud de nuestro país. Se debe determinar su punto de corte para cada zona geográfica, ya que este puede variar de acuerdo con la entidad nosológica que estemos investigando y la muestra de pacientes estudiados, pues varía con el sexo y las características étnicas. Su empleo ayuda a predecir el riesgo cardiometabólico y de mortalidad en las personas estudiadas. Conclusiones: el índice cintura/cadera es útil en la predicción del riesgo cardiometabólico. Su correcto empleo mejoraría la calidad de los servicios en los 3 niveles de atención de salud en nuestro país(AU)


Introduction: waist/hip index is presented as another element of the clinical assessment of obesity and its consequences. Objective: to describe the usefulness of waist / hip index in the detection of cardiometabolic risk. Methods: Google Scholar was used as a search engine and a total of 97 articles were obtained, of which 61 were referenced for fulfilling the stated objective. Results: obesity behaves like a multifactorial disease of chronic evolution, with important consequences for health. The increase in abdominal adipose tissue promotes greater synthesis and release of adipokines and other substances, which can impair lipid and carbohydrate metabolism through increased insulin resistance, and increase cardiovascular risk. Waist/hip index evaluates abdominal fat indirectly. It is an inexpensive indicator, easy to apply and easy to interpret in the 3 levels of health care in our country. Its cut-off point must be determined for each geographical area, since this may vary according to the nosological entity we are investigating and the sample of patients studied, as it varies with sex and ethnic characteristics. Its use helps to predict cardiometabolic risk and mortality in the people studied. Conclusions: Waist/hip index is useful in the prediction of cardiometabolic risk. Its correct use would improve the quality of services in the 3 levels of health care in our country(AU)


Subject(s)
Humans , Review Literature as Topic , Cardiovascular Diseases/prevention & control , Metabolic Syndrome/epidemiology , Waist-Hip Ratio/statistics & numerical data , Obesity/etiology , Body Weights and Measures/methods , Risk Reduction Behavior
11.
Rev. cuba. invest. bioméd ; 37(1): 57-64, ene.-mar. 2018. tab
Article in Spanish | LILACS (Americas) | ID: biblio-991091

ABSTRACT

En México como en el resto de Latinoamérica nuestros hábitos alimenticios nutricionales, culturales y educación favorecen a los factores de riesgo para desarrollar padecer diversas enfermedades crónicas degenerativas como la diabetes, hipertensión arterial, obesidad o trastornos como el aumento de colesterol y triglicérido. Cuando tres o más de los anteriores factores se presentan en conjunto proporcionan lo que conocemos como síndrome metabólico. El objetivo de este estudio fue determinar la prevalencia del síndrome metabólico de estudiantes con factores de riesgo para desarrollarlo en estudiantes universitarios. El estudio se realizó a estudiantes de primer año de la Universidad Veracruzana Campus Minatitlán, tomando en cuenta los resultados del Examen de Salud Integral que se les aplico al ingresar a la universidad, además se les realizó una prueba rápida de glucosa, somatometría y un cuestionario sociodemografico. Se estudió una población de 91 estudiantes de las facultades de Medicina, Odontología y Trabajo social de los cuales 73,6 por ciento eran mujeres y 26,4 por ciento hombres, en una edad promedio de 19.2 ± 1.1 años, encontrando una prevalencia de 6,6 por ciento de síndrome metabólico. Además se observó que 37,4 por ciento presentaron un factor de riesgo, 12 por ciento dos factores de riesgo y 44 por ciento no mostraron ningún factor de riesgo. Siendo el principal factor de riesgo la obesidad presente en 44 por ciento de los estudiantes, seguido de las hipertrigliceridemias. La prevalencia de síndrome metabólico en los estudiantes de nuevo ingreso de la facultad de medicina del campus Minatitlán es alta con respecto a los reportes nacionales e internaciones, en donde más del 50 por ciento presenta algún factor de riesgo, siendo la obesidad el principal con un mayor predominio en las mujeres(AU)


In Mexico as the rest of Latin America, our nutritional habits, cultural and educational favor to risk factors for developing chronic degenerative diseases such as diabetes, high blood pressure, obesity or disorders such as cholesterolemia, increased cholesterol and triglyceride. When three or more of the above factors are presented together provide which we know as metabolic syndrome. The objective of this study was to determine the prevalence of metabolic syndrome and risk factors for developing in university students. The study was conducted to first year students of the Health Sciences and Social Work at the Universidad Veracruzana campus Minatitlán, taking into account the results of the Integral Health Examination that were applied to them when entering the university, also was performed as a rapid glucose test, somatometry, and a socio-demographic questionnaire. A population of 91 students from the Faculty of Medicine, Dentistry and Social Work were studied, of which 73,6 percent were women and 26,4 percent were men, with a mean age of 19,2 ± 1,1 years, where 6,6 percent were found to have metabolic syndrome. We also observed that 37.4 percent had a risk factor, 12 percent had two risk factors and 44 percent did not show any risk factors. Being the main risk factor the obesity present in 44 percent of the students, followed by hypertriglyceridemia. The prevalence of metabolic syndrome in the newly enrolled students of the Health Sciences Area and Social Work of the Minatitlán campus is high with respect to national and international reports, where more than 50 percent presents some risk factor, being obesity the main one in a greater predominance in women(AU)


Subject(s)
Humans , Male , Female , Adolescent , Adult , Impacts on Health , Metabolic Syndrome/epidemiology , Universities
12.
An. bras. dermatol ; 93(2): 222-228, Mar.-Apr. 2018. tab
Article in English | LILACS (Americas) | ID: biblio-887185

ABSTRACT

Abstract: Background: Psoriasis has been associated with co-morbidities and elevated cardiovascular risk. Objectives: To analyze the relationships among metabolic syndrome, cardiovascular risk, C-reactive protein, gender, and Psoriasis severity. Methods: In this cross-sectional study, plaque Psoriasis patients (n=90), distributed equally in gender, were analyzed according to: Psoriasis Area and Severity Index, cardiovascular risk determined by the Framingham risk score and global risk assessment, C-reactive protein and metabolic syndrome criteria (NCEPT-ATP III). Results: Metabolic syndrome frequency was 43.3% overall, without significance between genders (P=0.14); but women had higher risk for obesity (OR 2.56, 95%CI 1.02-6.41; P=0.04) and systemic arterial hypertension (OR 3.29, 95%CI 1.39-7.81; P=0.006). The increase in the Psoriasis Area and Severity Index also increased the risk for metabolic syndrome (OR 1.060, 95%CI 1.006-1.117; P=0.03). Absolute 10-year cardiovascular risk was higher in males (P=0.002), but after global risk assessment, 51.1% patients, 52.2% women, were re-classified as high-intermediate cardiovascular risk; without significance between genders (P=0.83). C-reactive protein level was elevated nearly six-fold overall, higher in metabolic syndrome (P=0.05), systemic arterial hypertension (P=0.004), and high-intermediate 10-year cardiovascular risk patients (P<0.001); positively correlated to: Framingham risk score (P<0.001; r=0.60), absolute 10-year cardiovascular risk (P<0.001; r=0.58), and age (P=0.001; r=0.35); but not to Psoriasis Area and Severity Index (P=0.14; r=0.16); increased the 10-year cardiovascular risk (R2=33.6; P<0.001), MetS risk (OR 1.17, 95%CI 0.99-1.37; P=0.05) and with age (P=0.001). HDL-cholesterol level was higher in normal C-reactive protein patients (t=1.98; P=0.05). Study limitations: Restricted sample, hospital-based and representative of a single center and no specification of psoriatic arthritis. Conclusions: Psoriasis, metabolic syndrome, systemic arterial hypertension and age share the increase in C-reactive protein, which could implicate in additional burden for increasing the cardiovascular risk and be an alert for effective interventions.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Psoriasis/complications , Psoriasis/epidemiology , C-Reactive Protein/analysis , Cardiovascular Diseases/etiology , Metabolic Syndrome/complications , Metabolic Syndrome/epidemiology , Psoriasis/metabolism , Reference Values , Severity of Illness Index , Brazil/epidemiology , Comorbidity , Sex Factors , Anthropometry , Prevalence , Cross-Sectional Studies , Multivariate Analysis , Risk Factors , Sex Distribution , Risk Assessment , Hypertension/complications , Hypertension/epidemiology , Obesity/complications , Obesity/epidemiology
13.
An. bras. dermatol ; 93(2): 205-211, Mar.-Apr. 2018. tab
Article in English | LILACS (Americas) | ID: biblio-887203

ABSTRACT

Abstract: Background: Coexistence of obesity, hypertension, insulin resistance and dyslipidemia is defined as metabolic syndrome (MBS), which is among the important risk indicators for cardiovascular diseases, diabetes and stroke. Smoking and alcohol consumption are the other factors which lead to an increase in the risk of cardiovascular disease. Objective: To investigate the prevalence of metabolic syndrome, smoking and alcohol consumption in psoriasis patients and the relationship between disease severity and these factors. Methods: This cross-sectional study enrolled 563 patients with chronic plaque-type psoriasis, all of which completed a questionnaire and underwent a complete physical examination. Data about MBS components, psoriasis severity/duration, smoking and alcohol consumption, and cardiovascular diseases were recorded. Results: A total of 563 patients with ages ranging from 18 to 78 years were evaluated. Metabolic syndrome was found in 12.6% of the patients [central obesity (38.7%), hypertension (14.3%), dyslipidemia (18.6%), diabetes (9.2%)], while 50.3% had smoking, and 3.3% had alcohol consumption. Patients with metabolic syndrome were older and more likely to have a longer disease duration than those without metabolic syndrome (p<0.05 for each). The prevalence of metabolic syndrome was higher in women than in men. Psoriasis was more severe in patients with central obesity, diabetes and smoking than in those without (p<0.05 for each). Study Limitations: Retrospective design. Conclusions: Our results indicate that MBS is a risk factor for psoriasis patients with advanced age. The relationship between disease severity and obesity, diabetes, and smoking in psoriasis patients indicates that the patients should be informed about the potential metabolic risks and receive therapies for behavioral changes besides anti-psoriatic treatment in order to minimize these risks.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Young Adult , Psoriasis/epidemiology , Alcohol Drinking/epidemiology , Smoking/epidemiology , Metabolic Syndrome/epidemiology , Psoriasis/complications , Time Factors , Turkey/epidemiology , Alcohol Drinking/adverse effects , Cardiovascular Diseases/etiology , Smoking/adverse effects , Sex Factors , Epidemiologic Methods , Risk Factors , Age Factors , Sex Distribution , Age Distribution , Metabolic Syndrome/complications , Diabetes Mellitus/epidemiology , Dyslipidemias/complications , Dyslipidemias/epidemiology , Obesity, Abdominal/complications , Obesity, Abdominal/epidemiology , Hypertension/complications , Hypertension/epidemiology
14.
Rev. inf. cient ; 97(5): i:987-f:998, 2018. tab
Article in Spanish | LILACS (Americas) | ID: biblio-1005946

ABSTRACT

Introducción: la carga y amenaza mundial de las enfermedades no transmisibles socavan el desarrollo social y económico en todo el mundo. Objetivo: determinar la prevalencia de síndrome metabólico en la población de 15 a 74 años del municipio Guantánamo en 2010. Método: se realizó una investigación observacional transversal que incluyó 1 629 personas, seleccionadas mediante muestreo complejo, por conglomerados y polietápico. Para la definición de síndrome metabólico se utilizaron los criterios NCEP-ATP III modificados. Para recoger la información se utilizó la Versión Panamericana de la Encuesta Nacional de Vigilancia de Factores de Riesgo. Se determinó la prevalencia por edades y sexos mediante estimaciones con 95 por ciento de confiabilidad, expresadas en por ciento, utilizando el programa SPSS, versión 11.5. Resultados: el síndrome metabólico fue más frecuente en las mujeres y en el grupo de edades de 55-64 años. La prevalencia obtenida no difiere de los estimados realizados por la OMS y es un indicador que puede utilizarse como línea base para estudios posteriores que evalúen impacto de modificaciones en los factores de riesgo. Conclusiones: la alta prevalencia de SM en guantanameros de 15 a 74 años indica la necesidad de implementar acciones preventivas diseñadas para controlar la HTA, reducir la obesidad central, la dislipidemia y la hiperglicemia y mejorar la vigilancia de las enfermedades cardio-metabólicas y con ello evitar las consecuencias futuras del SM para la salud de la población(AU)


Introduction: the global burden and threat of noncommunicable diseases undermine social and economic development throughout the world. Objective: to determine the prevalence of metabolic syndrome in the population aged 15 to 74 years of the Guantánamo municipality in 2010. Method: a cross-sectional observational research was carried out that included 1 629 people, selected by complex sampling, by conglomerates and multistage. For the definition of metabolic syndrome the modified NCEP-ATP III criteria were used. To collect the information, the Pan American Version of the National Surveillance of Risk Factors Survey was used. The prevalence by age and sex was determined by means of estimations with 95percent reliability, expressed in percent, using the SPSS program, version 11.5. Results: Metabolic syndrome was more frequent in women and in the 55-64 age group. The prevalence obtained does not differ from the estimates made by WHO and is an indicator that can be used as a baseline for subsequent studies that assess the impact of changes in risk factors. Conclusions: the high prevalence of MS in guantanameros from 15 to 74 years indicates the need to implement preventive actions designed to control hypertension, reduce central obesity, dyslipidemia and hyperglycemia and improve the surveillance of cardio-metabolic diseases and thereby avoid the future consequences of MS for the health of the population(AU)


Introdução: a carga global e a ameaça de doenças não transmissíveis prejudicam o desenvolvimento social e econõmico em todo o mundo. Objetivo: determinar a prevalência da síndrome metabólica na população de 15 a 74 anos do município de Guantánamo em 2010. Método: foi realizada uma pesquisa observacional transversal que incluiu 1.629 pessoas, selecionadas por amostragem complexa, por conglomerados e multiestágios. Para a definição de síndrome metabólica foram utilizados os critérios modificados do NCEP-ATP III. Para coletar as informações, foi utilizada a versão pan-americana da Pesquisa Nacional de Vigilãncia de Fatores de Risco. A prevalência por idade e sexo foi determinada por meio de estimativas com 95 por cento de confiabilidade, expressas em porcentagem, utilizando o programa SPSS, versão 11.5. Resultados: A síndrome metabólica foi mais frequente em mulheres e na faixa etária de 55 a 64 anos. A prevalência obtida não difere das estimativas feitas pela OMS e é um indicador que pode ser usado como base para estudos posteriores que avaliam o impacto de mudanças nos fatores de risco. Conclusões: A alta prevalência de MS em Guantánamo a partir de 15 a 74 anos, indica a necessidade de executar acções preventivas destinadas a controlar a hipertensão, reduzir central de obesidade, dislipidemia e hiperglicemia e melhorar o controlo de doenças cardio-metabólicas e assim evitar as consequências futuras dos EM para a saúde da população(AU)


Subject(s)
Humans , Adolescent , Adult , Middle Aged , Aged , Risk Factors , Metabolic Syndrome/epidemiology , Observational Study
15.
Rev. latinoam. enferm. (Online) ; 26: e2983, 2018. tab
Article in English | LILACS (Americas) | ID: biblio-901928

ABSTRACT

ABSTRACT Objective: to estimate the prevalence of TaqIA, -141C and rs6280 polymorphisms of the ANKK1, DRD2 and DRD3 genes and evaluate their association with the occurrence of metabolic syndrome in patients with refractory schizophrenia. Method: cross-sectional study conducted in the Extended Western Region of Minas Gerais, with refractory schizophrenic patients using the antipsychotic clozapine. Sociodemographic, clinical, anthropometric, biochemical and genetic data were collected. Univariate analysis of the data was performed. Results: seventy-two patients participated in the study and the occurrence of Metabolic Syndrome was observed in 47.2% of them. There was no association between Metabolic Syndrome and the studied polymorphisms. There was a statistically significant difference in the low HDL parameter with homozygous genotype for the C allele of the -141C polymorphism of the DRD2 gene. Conclusion: a high prevalence of MS was evidenced. The -141C polymorphism was associated with low HDL. Genetic analysis and identification of metabolic alterations in this group of patients can guide drug treatment and provide a better quality of life.


RESUMO Objetivo: estimar a prevalência dos polimorfismos TaqIA, -141C e rs6280 dos genes ANKK1, DRD2 e DRD3 e avaliar sua associação com a ocorrência de síndrome metabólica em pacientes com esquizofrenia refratária. Método: estudo de delineamento transversal, realizado na Região Ampliada Oeste de Minas Gerais, que incluiu pacientes com esquizofrenia refratária em uso do antipsicótico clozapina. Foram coletados dados sociodemográficos, clínicos, antropométricos, bioquímicos e genéticos. Realizou-se análise univariada dos dados. Resultados: participaram 72 pacientes e observou-se a ocorrência de Síndrome Metabólica em 47,2%, não sendo encontrada associação da Síndrome Metabólica com os polimorfismos estudados. Houve diferença estatisticamente significante com o parâmetro do baixo HDL com genótipo homozigoto para alelo C do polimorfismo -141C do gene DRD2. Conclusão: evidenciou-se prevalência de SM elevada. O polimorfismo -141C associou-se ao baixo HDL. A análise genética e a identificação de alterações metabólicas, neste grupo de pacientes, podem nortear o tratamento medicamentoso e propiciar melhor qualidade de vida.


RESUMEN Objetivo: estimar la prevalencia de los polimorfismos TaqIA, -141C y rs6280 de los genes ANKK1, DRD2 y DRD3 y evaluar su asociación con el síndrome metabólico en pacientes con esquizofrenia refractária. Método: estudio de delineamiento transversal, realizado en la Región Ampliada Oeste de Minas Gerais, que incluye pacientes con esquizofrenia refractária usando el antipsicótico clozapina. Fueron recogidos datos sociodemográficos, clínicos, antropométricos, bioquímicos y genéticos. Se realizó um análisis univariada de los datos. Resultados: participaron 72 pacientes y se observó el Síndrome Metabólico en 47,2%, no siendo encontrada una asociación del Síndrome Metabólico con los polimorfismos estudiados. Hubo diferencia estadísticamente significante con el parámetro del bajo HDL con genotipo homozigoto para alelo C del polimorfismo -141C del gen DRD2. Conclusión: se vio una prevalencia de SM elevada. El polimorfismo -141C se asoció al bajo HDL. El análisis genético y la identificación de alteraciones metabólicas, en este grupo de pacientes, pueden guiar al tratamiento medicamentoso y propiciar mejor calidad de vida.


Subject(s)
Humans , Male , Female , Adult , Schizophrenia/complications , Schizophrenia/genetics , Receptors, Dopamine D2/genetics , Protein-Serine-Threonine Kinases/genetics , Metabolic Syndrome/complications , Metabolic Syndrome/genetics , Metabolic Syndrome/epidemiology , Polymorphism, Genetic
16.
Rev. latinoam. enferm. (Online) ; 26: e2983, 2018. tab
Article in English | LILACS (Americas), BDENF | ID: biblio-901949

ABSTRACT

ABSTRACT Objective: to estimate the prevalence of TaqIA, -141C and rs6280 polymorphisms of the ANKK1, DRD2 and DRD3 genes and evaluate their association with the occurrence of metabolic syndrome in patients with refractory schizophrenia. Method: cross-sectional study conducted in the Extended Western Region of Minas Gerais, with refractory schizophrenic patients using the antipsychotic clozapine. Sociodemographic, clinical, anthropometric, biochemical and genetic data were collected. Univariate analysis of the data was performed. Results: seventy-two patients participated in the study and the occurrence of Metabolic Syndrome was observed in 47.2% of them. There was no association between Metabolic Syndrome and the studied polymorphisms. There was a statistically significant difference in the low HDL parameter with homozygous genotype for the C allele of the -141C polymorphism of the DRD2 gene. Conclusion: a high prevalence of MS was evidenced. The -141C polymorphism was associated with low HDL. Genetic analysis and identification of metabolic alterations in this group of patients can guide drug treatment and provide a better quality of life.


RESUMO Objetivo: estimar a prevalência dos polimorfismos TaqIA, -141C e rs6280 dos genes ANKK1, DRD2 e DRD3 e avaliar sua associação com a ocorrência de síndrome metabólica em pacientes com esquizofrenia refratária. Método: estudo de delineamento transversal, realizado na Região Ampliada Oeste de Minas Gerais, que incluiu pacientes com esquizofrenia refratária em uso do antipsicótico clozapina. Foram coletados dados sociodemográficos, clínicos, antropométricos, bioquímicos e genéticos. Realizou-se análise univariada dos dados. Resultados: participaram 72 pacientes e observou-se a ocorrência de Síndrome Metabólica em 47,2%, não sendo encontrada associação da Síndrome Metabólica com os polimorfismos estudados. Houve diferença estatisticamente significante com o parâmetro do baixo HDL com genótipo homozigoto para alelo C do polimorfismo -141C do gene DRD2. Conclusão: evidenciou-se prevalência de SM elevada. O polimorfismo -141C associou-se ao baixo HDL. A análise genética e a identificação de alterações metabólicas, neste grupo de pacientes, podem nortear o tratamento medicamentoso e propiciar melhor qualidade de vida.


RESUMEN Objetivo: estimar la prevalencia de los polimorfismos TaqIA, -141C y rs6280 de los genes ANKK1, DRD2 y DRD3 y evaluar su asociación con el síndrome metabólico en pacientes con esquizofrenia refractária. Método: estudio de delineamiento transversal, realizado en la Región Ampliada Oeste de Minas Gerais, que incluye pacientes con esquizofrenia refractária usando el antipsicótico clozapina. Fueron recogidos datos sociodemográficos, clínicos, antropométricos, bioquímicos y genéticos. Se realizó um análisis univariada de los datos. Resultados: participaron 72 pacientes y se observó el Síndrome Metabólico en 47,2%, no siendo encontrada una asociación del Síndrome Metabólico con los polimorfismos estudiados. Hubo diferencia estadísticamente significante con el parámetro del bajo HDL con genotipo homozigoto para alelo C del polimorfismo -141C del gen DRD2. Conclusión: se vio una prevalencia de SM elevada. El polimorfismo -141C se asoció al bajo HDL. El análisis genético y la identificación de alteraciones metabólicas, en este grupo de pacientes, pueden guiar al tratamiento medicamentoso y propiciar mejor calidad de vida.


Subject(s)
Humans , Male , Female , Adult , Polymorphism, Genetic , Schizophrenia/complications , Schizophrenia/genetics , Receptors, Dopamine D2/genetics , Protein-Serine-Threonine Kinases/genetics , Metabolic Syndrome/complications , Metabolic Syndrome/genetics , Receptors, Dopamine D3/genetics , Prevalence , Cross-Sectional Studies , Metabolic Syndrome/epidemiology
17.
Belo Horizonte; s.n; 2018. 138 p. tab, ilus, mapa.
Thesis in Portuguese | LILACS (Americas), BDENF | ID: biblio-986590

ABSTRACT

Introdução: A importância da síndrome metabólica (SM) está relacionada à sua magnitude e forte associação com doenças cardiovasculares (DCV) e diabetes mellitus tipo 2 (DM2), dois dos principais problemas de saúde pública no Brasil e no mundo. Entre os fatores de risco para a SM, destaca-se o consumo alimentar. Contudo, essa associação não está bem dimensionada na população brasileira. Objetivo: Analisar os padrões alimentares e as suas associações independentes com SM em participantes da linha de base da Coorte de Universidades Mineiras (CUME). Métodos: Trata-se de um estudo transversal, cuja coleta de dados contemplou um questionário online autopreenchido (Q_0) com perguntas sobre características sociodemográficas, estilo de vida, morbidade referida, dados antropométricos, bioquímicos e clínicos. O consumo alimentar foi avaliado por meio de um Questionário de Frequência de Consumo Alimentar (QFCA) online de 144 itens alimentares. Além da coleta de dados online, foi realizada uma etapa presencial com uma subamostra aleatória para a validação da SM e dos seus componentes, definidos segundo a International Diabetes Federation (IDF). Para a identificação dos padrões alimentares foi utilizada a análise de componentes principais e as suas associações independentes com a SM foram estimadas pela regressão de Poisson com variâncias robustas. Resultados: O primeiro artigo apresentou o perfil de 4.291 participantes, sendo que a maioria era mulher (68%) e adulto jovem (72%, 20 a 39 anos); 14,9% relataram obesidade, 22,6% colesterol total alto, 11,6% hipertensão arterial e 3,3% DM2. No segundo artigo, conduzido com 172 participantes, verificou-se que o coeficiente Kappa entre diagnósticos de SM autodeclarado e aferido foi 0,814, indicando concordância quase perfeita. No terceiro artigo, foram avaliados 2.909 participantes (68,7% mulheres; média de idade de 36 ± 9,5 anos). A prevalência de SM foi de 7,0% (10,8% entre os homens e 5,3% entre as mulheres). Foram identificados quatro padrões alimentares: 1) padrão I = frutas, hortaliças, ovos, azeites, nozes e sementes e bebidas naturais; 2) padrão II = arroz e massas, leguminosas, cereais, raízes e tubérculos, pão francês, margarina e ingredientes culinários; 3) padrão III = carnes, bebidas alcoólicas e fast food; 4) padrão IV = lácteos, queijos e doces processados e pães ultraprocessados. Após o ajuste por fatores de confusão, o maior consumo (quarto versus o primeiro quartil) do padrão alimentar I e do padrão alimentar III foram associados, respectivamente, a menor (RP=0,47; IC95%: 0,27-0,82) e maior (RP=1,82; IC95%: 1,03-3,22) prevalências de SM. Além disso, a prevalência de SM aumentou diretamente com o maior consumo do padrão alimentar II (p de tendência=0,010). Conclusões: Apesar dos participantes do projeto CUME serem jovens e com alto nível de escolaridade, a presença de doenças crônicas foi frequente entre eles. Assim, a adoção de bons hábitos de vida se mostra importante nesse contexto, especialmente porque padrões alimentares saudável e não saudável se associaram, respectivamente, à diminuição e ao aumento da prevalência da SM.


Introduction: The importance of the metabolic syndrome (MetS) is related to its magnitude and strong association with cardiovascular diseases (CVD) and type 2 diabetes mellitus (DM2), two of the main public health problems in Brazil and in the world. Among the risk factors for MetS, we highlight food consumption. However, this association is not well-defined in the Brazilian population. Objective: To analyze dietary patterns and their independent associations with MetS in the baseline participants of the Cohort of Universities of Minas Gerais (CUME). Methods: This was a cross-sectional study whose data collection included a self-administered online questionnaire (Q_0) with questions about sociodemographic, lifestyle, referred morbidity, anthropometric, biochemical and clinical data characteristics. Consumption was assessed using an online Food Frequency Questionnaire (FFQ) of 144 food items. In addition to the online data collection, a face-to-face session was conducted with a random sub-sample for the validation of MetS and its components, according to the International Diabetes Federation (IDF). The principal components analysis was used to identify the food patterns, and their independent associations with SM were estimated by Poisson regression with robust variances. Results: The first manuscript presented the profile of 4,291 participants, most of whom were women (68%) and young adults (72%, 20-39 years); 14.9% reported obesity, 22.6% high total cholesterol, 11.6% hypertension and 3.3% DM2. In the second article, conducted with 172 participants, it was verified that the Kappa coefficient between diagnoses of self-reported and measured MetS was 0.814, indicating near perfect agreement. In the third article, 2,909 participants were evaluated (68.7% women, mean age 36 ± 9.5 years). The prevalence of MetS was 7.0% (10.8% among men and 5.3% among women). Four dietary patterns were identified: 1) pattern I = fruits, vegetables, eggs, olive oils, nuts and seeds and natural beverages; 2) pattern II = rice and pasta, legumes, cereals, roots and tubers, French bread, margarine and culinary ingredients; 3) pattern III = meat, alcoholic beverages and fast food; 4) pattern IV = processed dairy, cheeses and sweets and ultra-processed breads. After adjustments for confounding factors, the highest consumption (fourth versus first quartile) of pattern I and pattern III were associated, respectively, the lowest (PR = 0.47, 95% CI: 0.27-0, 82) and higher (PR = 1.82, 95% CI: 1.03-3.22) prevalence of MetS. Moreover, the prevalence of MetS increased directly with the higher consumption of dietary pattern II (p for trend = 0,010). Conclusions: Although the CUME participants were young and with a high schooling level, the presence of chronic diseases was frequent among them. Thus, the adoption of good life habits is important in this context, especially since healthy and unhealthy dietary patterns were associated, respectively, with the decrease and increase in the prevalence of MetS. I


Subject(s)
Humans , Male , Female , Adult , Metabolic Syndrome/complications , Metabolic Syndrome/epidemiology , Feeding Behavior , Socioeconomic Factors , Universities , Nutrition Surveys , Chronic Disease , Cross-Sectional Studies , Academic Dissertation , Metabolic Syndrome/diagnosis , Hypercholesterolemia , Hypertension , Obesity
18.
Motriz (Online) ; 24(3): e0062, 2018. tab, graf
Article in English | LILACS (Americas) | ID: biblio-976252

ABSTRACT

Abstract Aims: to identify the prevalence of metabolic syndrome (MetS) and associated risk factors in children. Methods: a total of 1,480 Brazilian children aged 6-10 years old (52.2% girls) participated in this population-based, epidemiological cross-sectional study. The inclusion criteria were children born between the years 2001 and 2006, of both sexes, who did not use remedy, were not on a calorie restriction diet, and who respected the 12-hour fast for blood collection. Anthropometric measurements, blood pressure, blood collection, and completion of the Previous Day Food Questionnaire and interview using a Physical Activity List were held at school. Parents were asked to complete a questionnaire on socioeconomic status and lifestyle habits of their child. Chi-square test compared proportions and factors associated with MetS were identified using Poisson Regression. Results: Girls had significantly higher MetS prevalence compared with boys (12.6% vs. 8.5%, p=0.046). After multivariable analysis, body fat percentage (p=0.001), fat mass (p<0.001), lean body mass (p< 0.001) and sedentary behavior (p= 0.050) were positively associated with MetS. Conclusions: Modifiable factors such as body fat percentage, fat mass, lean body mass and sedentary behavior were associated with MetS in children. Thus, interventions targeted for weight management, and adopting healthy habits such as reducing time in front of TV/computer/video game need to be part of the lifestyle of children.(AU)


Subject(s)
Humans , Male , Female , Child , Cardiovascular Diseases/epidemiology , Metabolic Syndrome/epidemiology , Brazil/epidemiology , Body Mass Index , Risk Factors , Sedentary Behavior
19.
Braz. oral res. (Online) ; 32: e35, 2018. tab, graf
Article in English | LILACS (Americas) | ID: biblio-889496

ABSTRACT

Abstract The aim of the present study was to evaluate the association between metabolic syndrome (MS) and periodontitis (PD), through a systematic review and meta-analysis. Original observational studies assessing the association between MS and PD in adults, published before May 11th (2017), were identified through electronic searches of MEDLINE, EMBASE and Cochrane Library databases. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline was used. For studies to be included, they had to mention the criteria used to diagnose MS and to have used at least one clinical measure to diagnose PD. There was no language restriction. Three reviewers independently identified eligible studies for possible inclusion in the systematic review and meta-analysis. The quality of the studies was evaluated by the Newcastle-Ottawa scale for observational studies. A random model meta-analysis was conducted. The strategies used to investigate heterogeneity were sequential analysis, subgroup analysis, univariate meta-regression and sensitivity analysis. Thirty-three studies met the inclusion criteria for the systematic review, and 26 had enough information to be included in the meta-analysis, totaling 52,504 patients. MS and PD were associated with an odds ratio of 1.38 (95%CI 1.26-1.51; I2 = 92.7%; p < 0.001). Subgroup analysis showed that complete periodontal examination (I2 = 70.6%; p < 0.001) partially explained the variability between studies. The present findings suggest an association between MS and PD. Individuals with MS are 38% more likely to present PD than individuals without this condition. Prospective studies should be conducted to establish cause and effect relations between MS and PD.


Subject(s)
Humans , Periodontitis/complications , Metabolic Syndrome/complications , Periodontitis/epidemiology , Metabolic Syndrome/epidemiology , Observational Studies as Topic
20.
Cad. Saúde Pública (Online) ; 34(9): e00105317, 2018. tab, graf
Article in English | LILACS (Americas) | ID: biblio-952462

ABSTRACT

The goals of this study were to develop reference values for waist circumference (WC) in Brazilian children between 6-10 years old and to evaluate the WC performance in predicting cardiovascular risk factors and metabolic syndrome (MetS) in children. This is a population-based epidemiological cross-sectional study, in which 1,397 children participated, with a 6-10 years old probability sampling and from public and private schools in the city of Uberaba, Minas Gerais State, Brazil. WC was measured at the waist narrowest point (WC1) and at the umbilicus level (WC2). Blood samples and blood pressure were collected to determine the MetS diagnosis. There was a significant effect of age (p = 0.001), anatomical point (WC1 vs. WC2, p = 0.001) and sex-anatomical point interaction (p = 0.016) for WC. Smoothed sex- and age-specific 5th, 10th, 25th, 50th, 75th, 90th and 95th percentile curves of WC1 and WC2 were designed by the LMS method. WC was accurate to predict MetS, for all ages [area under the ROC curve (AUC) > 0.79 and p < 0.05], regardless of sex. This study presented percentile curves for WC at two anatomical points in a representative sample of Brazilian children. Furthermore, WC was shown to be a strong predictor of cardiovascular risk factors and MetS in children.


O estudo teve como objetivos desenvolver valores de referência para perímetro de cintura (PC) em crianças brasileiras entre 6 e 10 anos de idade e avaliar o desempenho da PC na predição de fatores de risco cardiovasculares e de síndrome metabólica (SM) em crianças. O estudo epidemiológico transversal de base populacional incluiu 1.397 crianças entre 6 e 10 anos de idade, através de amostragem probabilística em escolas públicas e privadas em Uberaba, Minas Gerais, Brasil. A PC era medida no ponto mais estreito da cintura (PC1) e ao nível do umbigo (PC2). Foram coletadas amostras de sangue e medidas de pressão arterial para determinar o diagnóstico de SM. Os seguintes fatores mostram associação significativa com PC: idade (p = 0,001), ponto anatômico (PC1 vs. PC2, p = 0,001) e interação sexo/ponto anatômico (p = 0,016). O método LMS foi utilizado para desenhar as curvas suavizadas específicas para sexo e idade, dos percentis 5, 10, 25, 50, 75, 90 e 95. A PC mostrou-se acurada para a predição de SM, para todas as idades [área sob a curva ROC (AUC) > 0,79 e p < 0,05], independente de sexo. Conclusão: o estudo apresentou curvas de percentis de PC em dois pontos anatómicos em uma amostra representativa de crianças brasileiras. Além disso, a PC mostrou ser forte preditor de fatores de risco cardiovasculares e SM em crianças.


Los objetivos de este estudio fueron desarrollar valores de referencia para la circunferencia de cintura (WC por sus siglas en inglés), en niños brasileños entre 6-10 años de edad, y evaluar los resultados de WC para predecir factores de riesgo cardiovasculares y síndrome metabólico (MetS) en niños. Se trata de un estudio epidemiológico transversal, basado en población, en el que participaron 1.397 niños, de 6 a 10 años de edad con muestreo probabilístico, procedentes de escuelas públicas y privadas en la ciudad de Uberaba, Minas Gerais, Brasil. WC fue medido en el punto de cintura más estrecho (WC1) y al nivel del ombligo (WC2). Las muestras de sangre y presión arterial se recogieron para determinar el diagnóstico de MetS. Había un significativo efecto de la edad (p = 0.001), punto anatómico (WC1 vs. WC2, p = 0.001) y punto de interacción sexo-anatómico (p = 0.016) para el WC. Sexo uniforme y edad específica 5º, 10º, 25º, 50º, 75º, 90º y 95º curvas de percentil de WC1 y WC2 fueron diseñados mediante el método LMS. WC fue exacto para predecir MetS en todas las edades [área bajo la curva ROC (AUC) > 0.79 y p < 0.05], independientemente del sexo. Conclusión: este estudio presentó un percentil de curvas para WC en dos puntos anatómicos en una muestra representativa de niños brasileños. Asimismo, la WC se mostró como un fuerte predictor de factores de riesgo cardiovasculares y MetS en niños.


Subject(s)
Humans , Male , Female , Child , Cardiovascular Diseases/diagnosis , Risk Assessment/methods , Metabolic Syndrome/diagnosis , Waist Circumference/physiology , Reference Standards , Reference Values , Brazil/epidemiology , Cardiovascular Diseases/etiology , Cardiovascular Diseases/epidemiology , Body Mass Index , Sex Factors , Cross-Sectional Studies , Reproducibility of Results , Risk Factors , Analysis of Variance , Sensitivity and Specificity , Age Factors , Metabolic Syndrome/etiology , Metabolic Syndrome/epidemiology , Early Diagnosis , Pediatric Obesity/complications , Pediatric Obesity/epidemiology
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