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1.
Rev. cir. traumatol. buco-maxilo-fac ; 24(2): 39-44, abr.-jun. 2024. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-1572579

ABSTRACT

Sialolitos são formações calcificadas, podendo se desenvolver tanto nas glândulas salivares quanto nos seus ductos, devido à retenção de materiais orgânicos e inorgânicos que constituem a saliva. Sua presença é mais frequente nas glândulas salivares maiores, sendo as salivares menores dificilmente acometidas, com prevalência em pacientes do sexo masculino, entre a terceira e quarta década de vida. O objetivo desse trabalho é relatar um caso clínico de Sialolitíase no assoalho bucal na região de carúncula sublingual tratado cirurgicamente. Paciente do sexo masculino, 26 anos, leucoderma, encaminhado à Clínica de Estomatologia da UFPB para avaliação estomatológica. Na inspeção intraoral, foi detectada uma lesão nodular de consistência endurecida e coloração branco-amarelada, localizada no assoalho bucal na região de carúncula sublingual, com crescimento endofítico, base pediculada e superfície lisa, confirmando posteriormente o diagnóstico de Sialolitíase pela análise anatomopatológica. Optou-se pela excisão cirúrgica da lesão sob anestesia local, a qual foi realizada sem intercorrências. Após 6 meses de pós-operatório, não há sinais de recidiva da lesão. A sialolitíase, embora seja a patologia mais comum das glândulas salivares, apresenta excelente prognóstico. O exame clínico, associado ao exame radiológico convencional, podem ser suficientes no diagnóstico. Quanto mais precoce for o diagnóstico, menos invasivo será o procedimento... (AU)


Sialoliths are calcified formations, which can develop both in the salivary glands and in their ducts, due to the retention of organic and inorganic materials that constitute saliva. Its presence is more frequent in the major salivary glands, the minor salivary glands being rarely affected, with a prevalence in male patients between the third and fourth decade of life. The objective of this work is to report a clinical case of sialolithiasis on the floor of the mouth in the region of the sublingual caruncle, which was surgically treated. Male patient, 26 years old, Caucasian, referred to the UFPB Stomatology Clinic for stomatological evaluation. On intraoral inspection, a nodular lesion of hardened consistency and yellowish-white color was detected, located on the buccal floor in the sublingual caruncle region, with endophytic growth, pedicled base and smooth surface, later confirming the diagnosis of sialolithiasis by anatomopathological analysis. We opted for surgical excision of the lesion under local anesthesia, which was performed uneventfully. Six months after the operation, there are no signs of recurrence of the lesion. Sialolithiasis, although it is the most common pathology of the salivary glands, has an excellent prognosis. Clinical examination, associated with conventional radiological examination, may be sufficient for the diagnosis. The earlier the diagnosis, the less invasive the procedure... (AU)


Los sialolitos son formaciones calcificadas, que pueden desarrollarse tanto en las glándulas salivales como en sus conductos, debido a la retención de materiales orgánicos e inorgánicos que constituyen la saliva. Su presencia es más frecuente en las glándulas salivales mayores, siendo raramente afectadas las glándulas salivales menores, con un pre dominio en pacientes masculinos entre la tercera y cuarta década de la vida. El objetivo de este trabajo es reportar un caso clínico de sialolitiasis en el piso de la boca en la región de la carúncula sublingual, la cual fue tratada quirúrgicamente. Paciente masculino, 26 años, caucásico, remitido a la Clínica de Estomatología de la UFPB para evaluación estomatológica. A la inspección intraoral se detectó una lesión nodular de consistencia endurecida y color blanco amarillento, ubicada en el piso de la boca en la región de la carúncula sublingual, con crecimiento endófito, base pediculada y superficie lisa, confirmándose posteriormente el diagnóstico de sialolitiasis por análisis anatomopatológico. Se optó por la exéresis quirúrgica de la lesión bajo anestesia local, que se realizó sin incidencias. Seis meses después de la operación, no hay signos de recurrencia de la lesión. La sialolitiasis, aunque es la patología más común de las glándulas salivales, tiene un excelente pronóstico. El examen clínico, asociado al examen radiológico convencional, puede ser suficiente para el diagnóstico. Cuanto más temprano sea el diagnóstico, menos invasivo será el procedimiento... (AU)


Subject(s)
Humans , Male , Adult , Salivary Glands/pathology , Salivary Gland Calculi , Mouth Floor , Mouth Mucosa/pathology
2.
Int. j. odontostomatol. (Print) ; 18(2): 248-254, jun. 2024. ilus
Article in English | LILACS | ID: biblio-1564652

ABSTRACT

Pemphigus vulgaris (PV) and mucous membrane pemphigoid (MMP) are bullous autoimmune diseases that reach the oral mucosa and have common clinical features. The objective of the study was to present and compare the clinical manifestations of PV and MMP and the results of applied treatments. A case series of a stomatology service from 1985 to 2018. Data collection included epidemiological data, comorbidities, medications in use, duration of symptoms before the first visit, previous treatment, symptomatology, clinical description of lesions, presumptive diagnosis, histopathological description, extraoral manifestations, final diagnosis, treatment and follow-up. The medical records of 25 patients were analysed, 19 of whom were diagnosed with MMP and 6 with PV. The female gender was prevalent in MMP (84 %) and the male gender in PV (67 %). More than 60 % of patients complained of pain at their first visit. Patients with MMP took on average 6 months to seek professional help and patients with PV, about 2 months. Desquamative gingivitis was the most common lesion (63 %) in MMP and non-gingival ulcers (67 %) in PV. Minimal therapy was effective in all cases of MMP, and in PV one individual required minimal adjuvant therapy due to worsening of the case. Patients with PV have more intense signs and oral symptoms and may need more intensive treatment than patients with MMP. The use of topical and/or systemic corticosteroids was sufficient for most cases in both diseases.


Pénfigo vulgar (PV) y Penfigoide de la Membrana Mucosa (PMM) son enfermadades autoinmunes ampollosas que llegan a la mucosa oral y tienen características clínicas comunes. El objetivo de este estudio fue presentar y comparar las manifestaciones clínicas de PV y PMM y los resultados de los tratamientos aplicados. En el análisis se incluyó una serie de casos de un servicio de estomatología de 1985 a 2018. La recolección de información incluyó datos epidemiológicos, comorbilidades, medicamentos en uso, duración de los síntomas antes de la primera visita, tratamientos previos, sintomatología, descripción clínica de las lesiones, diagnóstico presuntivo, descripción histopatológica, manifestaciones extraorales, diagnóstico final, tratamiento y seguimiento. Se analizaron las historias clínicas de 25 pacientes, 19 de los cuales fueron diagnosticados de PMM y 6 de PV. El sexo feminino fue prevalente en PMM (84 %) y el sexo masculino en PV (67 %). Más del 60 % de los pacientes se quejaron de dolor durante la primera consulta. Los pacientes con PMM tardaron en promedio 6 meses en buscar ayuda profesional y los pacientes con PV, alrededor de 2 meses. La gingivitis descamativa fue la lesion más común (63 %) en PMM y las úlceras non gengivales (67 %) en PV. La terapia mínima fue efectiva en todos los casos de PMM, y en PV un individuo requirió terapia adyuvante mínima debido al empeoramiento del caso. Los pacientes con PV tienen signos y síntomas orales más intensos y pueden necesitar un tratamiento más intensivo que los pacientes con PMM. El uso de corticosteroides tópicos y/o sistémicos fue suficiente para la mayoría de los casos en ambas enfermedades.


Subject(s)
Humans , Male , Female , Middle Aged , Autoimmune Diseases/complications , Pemphigoid, Bullous/diagnosis , Pemphigoid, Bullous/pathology , Pemphigus/diagnosis , Pemphigus/pathology , Autoimmune Diseases/diagnosis , Autoimmune Diseases/pathology , Therapeutics , Prevalence , Skin Diseases, Vesiculobullous/complications , Skin Diseases, Vesiculobullous/diagnosis , Skin Diseases, Vesiculobullous/pathology , Mouth Mucosa/pathology
3.
Int. j. odontostomatol. (Print) ; 18(1): 41-50, mar. 2024. tab
Article in Spanish | LILACS | ID: biblio-1558170

ABSTRACT

El conocimiento de la patología oral, y su correcto diagnóstico es fundamental en Odontología, puesto que un diagnóstico tardío, particularmente en casos de lesiones premalignas o malignas, pueden conducir a serias consecuencias para el paciente. El objetivo de este trabajo fue establecer la congruencia diagnóstica clínica - histopatológica de lesiones en cavidad oral en pacientes que asistieron a la Facultad de Odontología, Universidad de Costa Rica, y a quienes se les realizó biopsia de la lesión, durante el período 2016-2019. El estudio fue descriptivo y retrospectivo, basado en datos de reportes histopatológicos en la población mencionada, por presentar alguna lesión, de tejidos blandos o duros, en cavidad oral. La muestra estadística fue por conveniencia, no probabilística y no aleatoria. Las técnicas estadísticas utilizadas fueron descriptivas para el análisis de la información, el cual se basó en la distribución de frecuencias y cruce de variables. El procesamiento estadístico de los datos se diseñó en una base de datos creada en Excel. La muestra comprendió 160 reportes histopatológicos de los cuales se excluyeron 14. La edad promedio de los pacientes fue 42 años (rango 2 - 78 años). La proporción hombre: mujer correspondió 1:1.4, predominado el sexo femenino en 58,9 %. La congruencia del diagnóstico histopatológico con el diagnóstico clínico correspondió a 55,8 %. La congruencia de los diagnósticos demuestra el conocimiento del profesional en identificar la lesión clínicamente de forma correcta, lo que permite actuar en el momento preciso y confirmar la impresión clínica diagnóstica de una patología mediante el estudio histopatológico, el cual es el estándar oro. El problema radica en aquellos casos en que hay discrepancia diagnóstica, pues exige conocer los factores responsables de esta discrepancia, exige la búsqueda de soluciones y exige reforzar y redireccionar la formación académica del profesional y de los estudiantes para reconocer y describir estas lesiones.


Knowledge of oral pathology and its correct diagnosis is fundamental in Dentistry, since a late diagnosis, particularly in cases of premalignant or malignant lesions, can lead to serious consequences for the patient. The objective of this study was to establish the clinical- histopathological diagnostic consistency of lesions in the oral cavity in patients who attended the Faculty of Dentistry, Universidad de Costa Rica, and who underwent a biopsy of the lesion, during the period 2016-2019. The study was descriptive and retrospective, based on data from histopathological reports in the mentioned population, due to presenting some lesion, soft or hard tissue, in the oral cavity. The statistical sample was for convenience, non- probabilistic nor random. The statistical techniques used were descriptive for the analysis of the information, which was based on frequency distribution and crossing of variables. The statistical processing of the data was designed in a database created in Excel. The sample collects 160 histopathological reports, of which 14 were excluded. The average age of the patients was 42 years (range between 2 - 78 years old).The male:female ratio corresponded to 1:1.4, with a predominance of the female sex at 58.9 %.The congruence of the histopathological diagnosis with the clinical diagnosis corresponded to 55.8 %. Diagnostic consistency demonstrates knowledge of the professional in correctly identifying the lesion clinically, which allows acting at the precise moment and confirming the diagnostic clinical impression of the pathology via histopathological study which is the gold standard. The problem lies in those cases in which there is a diagnostic discrepancy, since it requires having knowledge of the underlying factors and therefore, requires searching for solutions, reinforcing and redirecting the academic training of professionals and students to recognize and describe these lesions.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Mouth Neoplasms/diagnosis , Mouth Neoplasms/pathology , Schools, Dental/statistics & numerical data , Biopsy , Immunohistochemistry , Epidemiology, Descriptive , Retrospective Studies , Age and Sex Distribution , Melanocytes/pathology , Mouth Mucosa/pathology
4.
Rev. cir. traumatol. buco-maxilo-fac ; 23(3): 48-51, jul.-set. 2023. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-1561203

ABSTRACT

Objetivo: Relatar um caso de hiperplasia fibrosa inflamatória em lábio inferior, decorrente de um transtorno de comportamento repetitivo (mordedura) e o seu devido tratamento. Relato de caso: Paciente do gênero masculino, 27 anos de idade, apresentou aumento de volume em região de lábio inferior, indolor, com evolução clínica de seis a sete meses, com relatos de práticas de mordedura em região de lábio inferior. Ao exame clínico observou-se lesão exofítica em coloração de mucosa, pediculada, medindo cerca de 8mm, no seu maior diâmetro, com aspecto circunferencial, consistente à palpação e não sangrante. O paciente foi submetido à biópsia excisional, mantendo-se uma distância mínima de 5mm do pedículo. Conclusão: No caso relato, o paciente foi submetido a uma biópsia excisional com a completa remoção da lesão e obteve um prognóstico favorável... (AU)


Objective: To report a case of inflammatory fibrous hyperplasia in the lower lip, resulting from a repetitive be havior disorder (biting) and its proper treatment. Case report: Male patient, 27 year sold, presented pain less swelling in the lowerl ipregion, with clinical evolution of sixt o seven months, with report sof biting practices in the lower lip region. Clinical examination revealed an exophytic lesion in mucosal color, peduncula ted, mea suring about 8 mm in its largest diameter, with a circumferent ial appearance, consisten ton palpation and not bleeding. The patient underwent excisional biopsy, keeping a minimum distance of 5 mm from the pedicle. Conclusion: In the case report, the patient underwent a nexcision al biopsy with the complete removal of the lesion and obtained a favorable prognosis... (AU)


Objetivo: Informar de un caso de hiperplasia fibrosa inflamatoria del labio inferior debido a um trastorno de comportamiento repetitivo (morder) y su tratamiento. Reporte de caso: Paciente masculino, de 27 años, presentó un aumento de volumen em la región del labio inferior, indoloro, com evolución clínica de seis a siete meses, con reporte de prácticas de mordedura em la región del labio inferior. El examen clínico reveló una lesión exofítica, pedunculada, de coloración mucosa, que medía aproximadamente 8mm em su mayor diámetro, de aspecto circunferencial, consistente a la palpación y no sangrante. El paciente fue sometido a una biopsia excisional, manteniendo una distancia mínima de 5mm del pedículo. Conclusión: Em el caso relatado, el paciente fue sometido a una biopsia excisional com la remoción completa de lalesión y obtuvo um pronóstico favorable... (AU)


Subject(s)
Humans , Male , Adult , Mouth Neoplasms , Mouth Mucosa/surgery , Mouth Mucosa/pathology
5.
Int. j. odontostomatol. (Print) ; 17(1): 101-106, mar. 2023. ilus, graf
Article in English | LILACS | ID: biblio-1430547

ABSTRACT

Inflammatory fibrous hyperplasia (IFH) is a common reactive lesion in dental prostheses users that may be associated with chondroid metaplasia (CM). Metaplasia is an adaptive cellular process that may be caused by trauma. We reported here five cases of IFH associated with CM and analyzed morphologically the deposition of collagen in these lesions. Patients had a mean age of 58.8 years-old and were ill-fitting dental prostheses users. They presented nodular lesions located in the anterior maxilla. Microscopically, it was observed hyperplastic fibrous connective tissue with chronic inflammatory infiltrate and hyaline cartilage. No morphological differences were observed in collagen deposition under light microscopy, but quantitative analysis revealed a significantly higher collagen deposition at the connective tissue near CM (p = 0.015). IFH associated with CM affects ill-fitting dental prostheses users. The presence of CM is not significant to the lesion prognosis. However, its formation and the higher collagen deposition near it reinforces the IFH reactive origin.


La hiperplasia fibrosa inflamatoria (HFI) es una lesión reactiva común en los usuarios de prótesis dentales que puede estar asociada con la metaplasia cartilaginosa (MC). La metaplasia es un proceso celular adaptativo que puede ser causado por un trauma. El presente informe analizó cinco casos de HFI asociados a MC y se analizaron morfológicamente la deposición de colágeno en estas lesiones. Los pacientes tenían una edad media de 58,8 años y eran usuarios de prótesis dentales mal adaptadas. Se observaron lesiones nodulares localizadas en el la parte anterior del maxilar Microscópicamente se observó tejido conectivo fibroso hiperplásico con infiltrado inflamatorio crónico y cartílago hialino. No se observaron diferencias morfológicas en la deposición de colágeno bajo microscopía óptica, pero el análisis cuantitativo reveló una deposición de colágeno significativamente mayor en el tejido conectivo cerca de MC (p = 0,015). La HFI asociada con la MC afecta a los usuarios de prótesis dentales mal adaptadas. La presencia de MC no es significativa para el pronóstico de la lesión. Sin embargo, su formación y la mayor deposición de colágeno cerca de MC refuerza el origen reactivo de HFI.


Subject(s)
Humans , Female , Middle Aged , Aged , Mouth/pathology , Mouth Mucosa/pathology , Fibrosis , Radiography, Dental , Cartilage/pathology , Collagen , Hyperplasia/pathology
6.
Rev. otorrinolaringol. cir. cabeza cuello ; 83(3): 274-287, 2023. tab, ilus
Article in Spanish | LILACS | ID: biblio-1522106

ABSTRACT

Las lesiones de la cavidad oral corresponden a un hallazgo frecuente y muchas veces difíciles de diagnosticar. Su correcto reconocimiento podría ser clave en detectar patologías que podrían cambiar el pronóstico del paciente. El objetivo de esta revisión es describir una clasificación de las lesiones de la cavidad oral que permita ayudar al diagnóstico en la práctica clínica. Para esto, se detallan y se describen las lesiones, orientando al diagnóstico y a la necesidad de biopsiar. Para simplificar la orientación diagnóstica, las lesiones se clasifican en 2 grandes grupos: tumorales y no tumorales. Las lesiones no tumorales se subdividen en lesiones de la mucosa oral y lesiones de la lengua.


Lesions of the oral cavity are frequent and often difficult to diagnose. However, correct recognition could change the patient's prognosis. This review aims to describe a classification of oral mucosa lesions, to help the diagnosis in clinical practice. The lesions are described for this, guiding the diagnosis and the need for biopsy. To simplify the diagnostic orientation, the lesions are classified into two groups: tumor and non-tumor lesions. Non-tumor lesions are subdivided into lesions of the oral mucosa and lesions of the tongue.


Subject(s)
Humans , Mouth Mucosa/pathology , Biopsy/methods , Mouth/pathology
7.
J. oral res. (Impresa) ; 11(6): 1-11, nov. 3, 2022. ilus, tab
Article in English | LILACS | ID: biblio-1437487

ABSTRACT

Background: Numerous types of cancer are of substantial medical and social concern, posing a major challenge to modern medicine. Chemotherapeutic drugs include the use of nucleosides, which are composed of nucleic acid and sugar. Objective: This study aims to assess the impact of systemic chemotherapeutic drugs at a therapeutic dose on the wound healing process of the oral mucosa. Material and Methods: 30 healthy rats were randomly divided into two main groups based on the study material, 15 rats in each group. Group A (control) was given a single dose of normal saline (1ml/kg, intraperitoneal), and Group B (study) a single injection of gemcitabine (50 mg /Kg, intraperitoneal). After anesthesia, a full-thickness soft tissue incision (0.5 cm length) on the right side of the buccal mucosa was made in the animals of both groups. Each group was subdivided according to the time of sacrifice into 3, 7, 14 days after surgery, at the end of the experimental periods, specimens were collected for histopathological study, and samples of blood were obtained from retro-orbital venous plexus and collected in microfuge tubes and levels of antioxidant enzymes were measured by ELISA. The data were analyzed statistically at a 0.05 level of significance. Results: Gemcitabine delayed the onset of wound cascade (inflammation and re-epithelization) which lead to worsening healing of the oral tissue; it also resulted in a decrease of the antioxidant activity of glutathione peroxidase and catalase, as well as activated caspase 3, which induces cell apoptosis. Conclusion: Gemcitabine showed negative feedback on oral tissue wound healing through delayed wound healing cascade and by inducing apoptosis.


Antecedentes: numerosos tipos de cáncer son motivo de gran preocupación médica y social, lo que representa un gran desafío para la medicina moderna. Los fármacos quimioterapéuticos incluyen el uso de nucleósidos, que están compuestos de ácido nucleico y azúcar. Objetivo: Este estudio tiene como objetivo evaluar el impacto de los fármacos quimioterapéuticos sistémicos a una dosis terapéutica en el proceso de cicatrización de heridas de la mucosa oral. Material y Métodos: 30 ratas sanas se dividieron aleatoriamente en dos grupos principales según el material de estudio, 15 ratas en cada grupo. Al grupo A (control) se le administró una dosis única de solución salina normal (1 ml/kg, intraperitoneal) y al grupo B (estudio) una inyección única de gemcitabina (50 mg/kg, intraperitoneal). Después de la anestesia, se realizó una incisión de tejido blando de espesor total (0,5 cm de longitud) en el lado derecho de la mucosa bucal en los animales de ambos grupos. Cada grupo se subdividió de acuerdo al tiempo de sacrificio en 3, 7, 14 días después de la cirugía, al final de los períodos experimentales se colectaron especímenes para estudio histopatológico, se obtuvieron muestras de sangre del plexo venoso retroorbitario y se recolectaron en tubos de microcentrífuga y los niveles de enzimas antioxidantes se midieron por ELISA. Los datos se analizaron estadísticamente a un nivel de significación de 0,05. Resultados: La gemcitabina retrasó el inicio de la cascada de heridas (inflamación y reepitelización) que condujo a un empeoramiento de la cicatrización del tejido oral; también resultó en una disminución de la actividad antioxidante de la glutatión peroxidasa y la catalasa, así como de la caspasa 3 activada, que induce la apoptosis celular. Conclusión: La gemcitabina mostró retroalimentación negativa sobre la cicatrización de heridas del tejido oral a través de una cascada de cicatrización retardada y mediante la inducción de apoptosis.


Subject(s)
Animals , Rats , Wound Healing/drug effects , Gemcitabine/therapeutic use , Mouth Mucosa/pathology , Antineoplastic Agents
8.
Arch. pediatr. Urug ; 93(1): e306, jun. 2022. ilus
Article in Spanish | LILACS, UY-BNMED, BNUY | ID: biblio-1383647

ABSTRACT

La hiperplasia de glándulas sebáceas es un hallazgo benigno y transitorio, común en el período neonatal. Secundariamente al estímulo hormonal androgénico se produce un hipercrecimiento de las glándulas, con mayor frecuencia en nariz y mejillas, donde existen en mayor densidad. La hiperplasia de glándulas en una localización ectópica, llamada gránulos de Fordyce (GF), es excepcional en el período neonatal. Se han reportado en aproximadamente 1% de los recién nacidos, y con frecuencia se localizan en la mucosa oral. Los GF se describen como lesiones papulares de aspecto vesiculoso blanco amarillentas de 1-3 mm2, que podrían confundir al neonatólogo o al pediatra con entidades infecciosas, dando lugar a pruebas invasivas y tratamientos innecesarios. Se describen tres casos clínicos de neonatos con diagnóstico de hiperplasia sebácea ectópica localizada en mucosa oral, con el objetivo de revisar la etiología, las características clínicas, los diagnósticos diferenciales y la evolución de esta entidad benigna. Conclusiones: la hiperplasia sebácea ectópica en mucosa oral de neonatos es un hallazgo benigno autolimitado que se presenta con baja frecuencia. El reconocimiento clínico de esta entidad es importante para evitar diagnósticos incorrectos y tratamientos innecesarios.


Sebaceous gland hyperplasia is a common transient and benign finding in neonates. After androgenic hormonal stimulation, there is a gland overgrowth mainly in the nose and cheeks where there is a greater density of glands. Ectopic sebaceous gland hyperplasia, called Fordyce's Granules (FG), is exceptional in neonates and it is reported in approximately 1% of newborns and frequently located in the oral mucosa. FGs are described as 1-3mm2 yellowish-white papular and vesicular lesions. Neonatologists or pediatricians may confuse these clinical features with infectious diseases, leading to invasive tests and unnecessary treatment. We describe three clinical cases of neonates with diagnosis of ectopic sebaceous gland hyperplasia located in the oral mucosa, with the aim of reviewing the etiology, clinical characteristics, differential diagnoses and evolution of this benign entity. Conclusions: ectopic sebaceous gland hyperplasia of the lips is a self-limited benign finding occurring infrequently in newborns. The clinical recognition of this entity is important to avoid inaccurate diagnoses or unnecessary treatment.


A hiperplasia das glândulas sebáceas é um achado benigno e transitório comum nos neonatos. Secundário ao estímulo hormonal androgênico, há um hipercrescimento das glândulas com mais frequência no nariz e nas bochechas onde há uma maior densidade das glândulas. A hiperplasia das glândulas num local ectópico, chamado Fordyce Granules (FG), é excepcional no período neonatal, e ela é relatada em aproximadamente 1% dos recém-nascidos e muitas vezes está localizada na mucosa oral. Os FGs são descritos como lesões vesiculares brancas amareladas de 1-3mm2, o que poderia confundir o neonatologista ou pediatra com entidades infecciosas, levando a testes invasivos e tratamentos desnecessários. Descrevemos três relatos clínicos de recém-nascidos com diagnóstico de hiperplasia sebácea ectópica localizada na mucosa oral, com o objetivo de rever a etiologia, características clínicas, diagnósticos diferenciais e evolução desta entidade benigna. Conclusões: hiperplasia sebácea ectópica na mucosa oral de recém-nascidos é um achado benigno autolimitante que ocorre com baixa frequência. O reconhecimento clínico desta entidade é importante para evitar diagnósticos incorretos e tratamentos desnecessários.


Subject(s)
Humans , Male , Infant, Newborn , Streptococcal Infections/diagnosis , Streptococcus agalactiae , Herpes Simplex/diagnosis , Hyperplasia/diagnosis , Mouth Mucosa/pathology , Diagnosis, Differential
9.
Int. j. odontostomatol. (Print) ; 16(2): 331-336, jun. 2022. ilus, tab
Article in English | LILACS | ID: biblio-1385892

ABSTRACT

ABSTRACT: Oral mucosal melanoma is an unusual and aggressive malignant tumor that mainly affects the palate of men aged between 50 and 60 years. We present a literature review focusing on the etiopathogenesis and the clinicopathologic features of this entity. In addition, we reported a rare case of an oral mucosal melanoma arising in the left cheek of a 60-yea r- old man. Computed tomography scan revealed infiltration of the tumor to other anatomic structures including the maxillary sinus, the zygomatic bone and the pterygoid processes. Based on its extension, the lesion was considered inoperable and treatment with three-dimensional conformal radiation therapy was proposed but the patient only attended to the first session and died from cancer progression 6 months after the diagnosis. This paper reinforces the importance of inclusion of this malignant tumor in the differential diagnosis of pigmented lesions of the oral mucosa.


RESUMEN: El melanoma de la mucosa oral es un tumor maligno inusual y agresivo que afecta principalmente al paladar de hombres de entre 50 y 60 años. Presentamos una revisión bibliográfica centrada en la etiopatogenia y las características clínico-patológicas de esta entidad. Además, reportamos un caso raro de melanoma de la mucosa oral que surgió en la mejilla izquierda de un hombre de 60 años. La tomografía computarizada reveló la infiltración del tumor a otras estructuras anatómicas, incluido el seno maxilar, el hueso cigomático y los procesos pterigoideos. En base a su extensión, la lesión se consideró inoperable y se propuso tratamiento con radioterapia conformada tridimensional pero el paciente solo asistió a la primera sesión y falleció por progresión del cáncer 6 meses después del diagnóstico. Este trabajo refuerza la importancia de la inclusión de este tumor maligno en el diagnóstico diferencial de las lesiones pigmentadas de la mucosa oral.


Subject(s)
Humans , Male , Middle Aged , Skin Neoplasms/pathology , Melanoma/surgery , Melanoma/diagnostic imaging , Immunohistochemistry , Tomography, X-Ray Computed , Diagnosis, Differential , Melanoma, Cutaneous Malignant , Mouth Mucosa/pathology
10.
Article in English | LILACS, BBO | ID: biblio-1422290

ABSTRACT

Abstract Objective: To quantify and compare respiratory functions and further screen the oral mucosa of tobacco and non-tobacco users. Material and Methods: First control group, non-tobacco users (n=55); Second group, smokers' group (n=168) who currently smoked cigarettes; Third group smokeless/chewing type, tobacco group (n=81); Fourth group, both smokeless and smoking type tobacco users (n=46). Fagerstrom Test for Nicotine Dependences (FTND) and Fagerström Test for Nicotine Dependence-Smokeless Tobacco (FTND-ST) instruments were used to assess nicotine dependence. Subsequently, spirometry and Toluidine Blue (TB) vital staining were performed. Chi-squared and one-way analysis of variance (ANOVA) were used for statistical analysis. Results: Fagerstrom test resulted in 48.8% of subjects with low dependency, followed by an increase in nicotine dependency from low to moderate (29.2%), moderate (15.6%), and highly dependent (6.4%) groups. All respiratory function tests and oral screening confirmed significant changes amongst tobacco and non-tobacco users. The forced vital capacity of non-smoker group was significantly different from other tobacco users' group (p<0.05). Conclusion: Early effects of tobacco use can lead to complications with the respiratory system and oral cavity. Such data can be used to delineate the harm of tobacco and should be used to urge individuals to evade the utilization of tobacco (AU).


Subject(s)
Humans , Male , Adolescent , Adult , Middle Aged , Spirometry/methods , Tobacco Use Disorder , Lung Volume Measurements/instrumentation , Mouth Mucosa/pathology , Nicotine/adverse effects , Chi-Square Distribution , Cross-Sectional Studies/methods , Surveys and Questionnaires , Analysis of Variance , India/epidemiology
11.
Autops. Case Rep ; 12: e2021360, 2022. tab, graf
Article in English | LILACS | ID: biblio-1360154

ABSTRACT

Verruciform xanthoma (VX) is a rare benign lesion of unknown etiology, with a rough or papillary aspect, painless, sessile, well-defined, most lesions do not exceed 2 cm in their largest diameter, the degree of keratinization of the surface influences color, varying white to red, affecting mainly the gingiva and alveolar mucosa, and can also be seen in skin and genital. Herein, we present a report a clinical case of oral verruciform xanthoma in the buccal mucosa associated with the lichen planus lesion, as well as the morphological and immunohistochemical characteristics of the lesion. The clinical diagnostic hypothesis of oral lichen planus of the white reticular lesions on the buccal mucosa and on the tongue was confirmed by histopathology before a subepithelial connective tissue exhibiting intense inflammatory infiltrate in a predominantly lymphocytic band. In contrast, the hypothesis of the verrucous lesion in the left buccal mucosa was leukoplakia, with histopathological evidence showing exophytic and digitiform proliferations with parakeratin plugs between the papillary projections. Subepithelial connective tissue was characterized by macrophages with foamy cytoplasm (xanthoma cells). An immunohistochemical examination was performed, showing positivity for CD68, a macrophage marker, in addition to testing by Schiff's periodic acid (PAS) with diastasis, which was detected the presence of lipids inside these macrophages. The patient is free of recurrences of verruciform xanthoma and is being monitored due to the presence of lesions of oral lichen planus.


Subject(s)
Humans , Female , Aged , Xanthomatosis/complications , Lichen Planus, Oral/complications , Immunohistochemistry , Xanthomatosis/pathology , Lichen Planus, Oral/pathology , Mouth Mucosa/pathology
12.
Rev. ADM ; 78(6): 361-364, nov.-dic. 2021. ilus
Article in Spanish | LILACS | ID: biblio-1357715

ABSTRACT

El lipoma es un tumor benigno derivado de tejido adiposo maduro que se presenta con poca frecuencia en la cavidad oral, pero de interés para el clínico estomatológico por su distintiva presentación en esta región. A continuación se reportan dos casos clínicos de lipoma simple localizados en la mucosa vestibular y piso de boca que fueron tratados mediante eliminación quirúrgica (AU)


Lipoma is a benign neoplasm derived of mature adipose tissue that occurs infrequently in the oral cavity, but of interest to the stomatologic clinician for its distinctive presentation in this region. Next, two cases of simple lipoma located in the vestibular mucosa and floor of the mouth that were treated by surgical excision are presented (AU)


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Oral Surgical Procedures , Lipoma , Mouth Mucosa/pathology , Schools, Dental , Neoplasms, Adipose Tissue , Age and Sex Distribution , Mexico
13.
Natal; s.n; 15 set. 2021. 72 p. tab, ilus.
Thesis in Portuguese | LILACS, BBO | ID: biblio-1533080

ABSTRACT

O surto de um novo coronavírus SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), foi identificado em Wuhan, na China no final de 2019. O SARS-CoV-2, se propaga através de gotículas respiratórias de uma pessoa infectada e causa uma doença respiratória denominada Covid-19 (Coronavirus Disease, 2019). Seu comportamento clínico é variável e manifesta-se com sintomas leves ou moderado, podendo desenvolver uma infecção respiratória grave. A cavidade oral foi identificada como uma das portas de entrada para o SARS-CoV-2, e seu possível papel como agravante na infectividade e progressão da infecção viral têm sido controversos. Foi realizado um estudo de coorte retrospectivo com dados obtidos de 274 prontuários de pacientes com COVID-19. Foi coletado dados na admissão do paciente, com sete e quatorze dias para analisar a ocorrência de alterações bucais e relacioná-las com a severidade da infecção. Foram encontrados 154 pacientes com alteração bucal e 120 sem alteração. Dos 154 pacientes que apresentaram alteração bucal na admissão, 39 obtiveram remissão em 7 dias, 54 pacientes obtiveram remissão em 14 dias e 61 mantiveram alteração bucal até o fim do estudo. Dos 120 pacientes que não apresentavam alteração bucal na admissão, apenas 2 desenvolveram alteração bucal em 7 dias e estes foram a óbito. A alteração bucal mais frequente foi a úlcera nos três tempos de coleta ( T0: 43,8%, T1: 33,6% e T2: 21,2%). As análises dos exames complementares alteradas mais prevalentes entre os pacientes foram as hemácias, plaquetas, leucócitos, tempo de sangramento, TGP, TGO, albumina, creatinina, PCR, ureia, d-dímero e razão leucócito-linfócito. Não foram observados fatores preditores para o desenvolvimento de alterações bucais em pacientes com COVID 19. As alterações em mucosa oral foram observadas na maioria dos pacientes com COVID-19 analisados nessa pesquisa. Não foi observada associação entre as comorbidades e a presença de lesões orais nos pacientes avaliados. Os fatores de prognósticos foram avaliados pela análise multivariada de Cox que determinou que não fazer uso de medicação para o aparelho digestivo e metabolismo (HR: 2,18; IC95%: 1,13-4,22) e não apresentar hipertensão arterial sistêmica (HR: 1,78; IC95%: 1,13- 2,79) são fatores prognósticos para remissão de alteração bucal em pacientes com COVID-19 (AU).


An outbreak of a new SARS-CoV-2 coronavirus (Severe acute respiratory syndrome coronavirus 2) was identified in Wuhan, China in late 2019. SARS-CoV-2, spreads through respiratory droplets from an infected person and causes a respiratory disease called Covid-19 (Coronavirus Disease, 2019). Its clinical behavior is variable and manifests with mild or moderate symptoms, and may develop a severe respiratory infection. The oral cavity has been identified as one of the gateways for SARS-CoV-2, and its possible role as an aggravating factor in the infectivity and progression of viral infection has been controversial. A retrospective cohort study was carried out with data obtained from 274 medical records of patients with COVID-19. Data was collected on the admission of the patient, with seven and fourteen days to analyze the occurrence of oral changes and relate them to the severity of the infection. A total of 154 patients with oral alterations and 120 without alterations were found. Of the 154 patients who presented oral changes on admission, 39 achieved remission within 7 days, 54 patients achieved remission within 14 days, and 61 maintained oral changes until the end of the study. Of the 120 patients who did not present oral changes on admission, only 2 developed oral changes within 7 days and these died. The most frequent oral alteration was an ulcer in the three collection times (T0: 43.8%, T1: 33.6% and T2: 21.2%). The most prevalent abnormal exam analyses among patients were red blood cells, platelets, leukocytes, bleeding time, TGP, TGO, albumin, creatinine, CRP, urea, d-dimer, and leukocyte-lymphocyte ratio. No predictors were observed for the development of oral alterations in patients with COVID 19. Alterations in the oral mucosa were observed in most patients with COVID-19 analysed in this study. There was no association between comorbidities and the presence of oral lesions in the patients evaluated. Prognostic factors were evaluated by Cox's multivariate analysis, which determined that they did not use medication for the digestive system and for metabolism (HR: 2.18; 95%CI: 1.13- 4.22) and did not have systemic arterial hypertension (HR: 1.78; 95%CI: 1.13-2.79), these are prognostic factors for remission of oral changes in patients with COVID-19 (AU).


Subject(s)
Humans , Male , Female , Prognosis , Hospital Care , COVID-19/transmission , Mouth/pathology , Mouth Mucosa/pathology , Chi-Square Distribution , Survival Analysis , Medical Records , Retrospective Studies , Cohort Studies
14.
Rev. ADM ; 78(3): 167-175, mayo-jun. 2021. ilus
Article in Spanish | LILACS | ID: biblio-1254949

ABSTRACT

La actual pandemia de COVID-19 provocada por el virus SARS-CoV-2 es un problema de salud que afecta a la población globalmente. Su desarrollo puede ser asintomático o exhibir manifestaciones clínicas moderadas o severas dependiendo en gran medida de la respuesta inmune de quien la padece. Esta enfermedad afecta principalmente a los pulmones a través del desarrollo del síndrome respiratorio agudo severo (SRAS), tanto como por la «tormenta de citocinas¼, una respuesta inflamatoria exacerbada que podría provocar una falla multisistémica y, en casos severos, la muerte. Se conoce que la enzima convertidora de angiotensina 2 (ECA-2), presente en diversos tejidos del cuerpo, actúa como receptor funcional del virus SARS-CoV-2 facilitando la entrada de éste a las células. Se ha demostrado la presencia de dicho receptor en varios tejidos orales, por lo que se puede considerar a la cavidad bucal como una vía latente de infección por dicho coronavirus, ya que su mecanismo de transmisión es a través de la inhalación de partículas virales, ya sea por vía nasal u oral. Así mismo, la presencia de carga vírica en la saliva y algunos de los síntomas de la COVID-19, por ejemplo la ageusia, pueden indicar la presencia de contagio viral en etapas tempranas. La presente revisión muestra evidencia que sugiere que diversos tejidos en la cavidad oral podrían ser considerados sitios potenciales de contagio por el SARS-CoV-2, teniendo un papel importante en el mecanismo de transmisión y en el desarrollo de coinfecciones (AU)


The COVID-19 pandemic caused by the SARS-CoV-2 virus is currently a global healthcare problem. The onset of this disease can exhibit several clinical manifestations ranging from mild to severe symptoms, depending on the individual's immune response. COVID-19 primarily affects the lungs by developing the Severe Acute Respiratory Syndrome (SARS) and the «cytokine storm¼, an exacerbated inflammatory reaction that can lead to multiorgan failure and consequently death. The angiotensin-converting enzyme 2 (ACE-2), present in several tissues in the human body, is known to act as the functional receptor of the SARS-CoV-2 germ facilitating its entrance into the cells. Such receptor is also present in diverse oral cavity tissues, indicating a latent route of infection due to its influence in the transmission mechanism by inhalation, either oral or nasal, of virus particles. Also, viral load in saliva and taste disorder symptoms like ageusia could indicate a viral infection in its early stages. This article presents evidence suggesting that several tissues in the oral cavity can be considered potential sites of SARS-CoV-2 infection, thus playing an essential role in the transmission mechanism and development of co-infections (AU)


Subject(s)
Humans , SARS-CoV-2 , COVID-19 , Mouth Mucosa/pathology , Oral Manifestations , Signs and Symptoms , Taste Disorders , Peptidyl-Dipeptidase A , Viral Load , Inflammation
15.
Int. j. odontostomatol. (Print) ; 15(2): 315-319, jun. 2021. ilus
Article in English | LILACS | ID: biblio-1385746

ABSTRACT

COVID-19 was characterized as a pandemic due to the worldwide dissemination and the severity with which the disease attacks the human organism. Some oral lesions have been observed in COVID-19 patients. However, there is still no concrete evidence of the real influence of SARS-CoV-2 on the human body, especially in the oral region. In this context, the present report discusses a case of a COVID-19 patient with oral alterations. The male patient presented ulcerative lesions of painful symptomatology and petechiae in the oral mucosa. This study also performed a literature review of the main oral alterations reported in the literature. Although more studies with a larger number of cases should be performe d, the present clinical case may have manifested signs of this pathology in the oral cavity since the epithelial cells of the oral mucosa have ACE2 receptors.


El COVID-19 se caracterizó como una pandemia debido a la diseminación mundial y la gravedad con la que la enfermedad ataca al organismo humano. Se han observado algunas lesiones orales en pacientes con COVID-19. Sin embargo, todavía no hay evidencia concreta de la influencia del SARS-CoV-2 en el cuerpo humano, especialmente en la cavidad oral. En este contexto, el presente reporte analiza un caso de un paciente con COVID-19 con alteraciones orales. El paciente de sexo masculino presentó lesiones ulcerativas de sintomatología dolorosa y petequias en la mucosa oral. Este estudio también realizó una revisión de la literatura de las principales alteraciones orales reportadas en la literatura. Si bien se deben realizar más estudios con un mayor número de pacientes, el presente reporte de caso puede haber manifestado signos de esta patología en la cavidad oral ya que las células epiteliales de la mucosa oral tienen receptores ACE2.


Subject(s)
Humans , Male , Adult , COVID-19/complications , Mouth Diseases/pathology , Mouth Mucosa/pathology , Oral Health , Oral Ulcer/pathology , Inflammation/pathology
16.
Medisan ; 25(1)ene.-feb. 2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1154846

ABSTRACT

Introducción: Las lesiones paraprotésicas son alteraciones de la mucosa bucal asociadas al uso de prótesis dental, las cuales pueden provocar complicaciones graves. Objetivo: Identificar los factores de riesgo relacionados con las lesiones paraprotésicas en pacientes portadores de prótesis removibles. Métodos: Se realizó un estudio observacional y descriptivo de 180 pacientes con lesiones paraprotésicas, atendidos en la Clínica Estomatológica Provincial Docente Mártires del Moncada de Santiago de Cuba, desde febrero del 2019 hasta mayo del 2020. Se seleccionaron las siguientes variables: edad, sexo, factor de riesgo y tipo de lesión paraprotésica. Resultados: Predominaron los pacientes de 60 años y más, la estomatitis subprótesis (52,7 %) y factores de riesgo, tales como prótesis mucosoportada, mayor tiempo de uso, así como hábito de dormir con la prótesis. Conclusiones: La lesión paraprotésica más frecuente fue la estomatitis subprótesis debido a la persistencia de los mismos factores de riesgo, que incidieron en la población a través del tiempo.


Introduction: Paraprosthetic lesions are alterations of the oral mucosa associated with the use of dental prosthesis, which can cause serious complications. Objective: To identify the risk factors related to the paraprosthetic lesions in patients with removable prosthesis. Method: An observational and descriptive study of 180 patients with paraprosthetic lesions was carried out; they were assisted in Mártires del Moncada Teaching Provincial Stomatological Clinic in Santiago de Cuba, from February, 2019 to May, 2020. The following variables were selected: age, sex, risk factor and type of paraprosthetic lesion. Results: There was a prevalence of the 60 years and over patients, sub prosthesis stomatitis (52.7 %) and risk factors, such as mucosoported prosthesis, longer time using it, as well the habit of sleeping with the prosthesis. Conclusions: The most frequent paraprosthetic lesion was the sub prosthesis stomatitis due to the persistence of the same risk factors that impacted in the population through the time.


Subject(s)
Dental Prosthesis/adverse effects , Mouth Mucosa/pathology , Risk Factors
17.
Acta toxicol. argent ; 28(2): 36-44, Sept. 2020. graf
Article in English | LILACS | ID: biblio-1278221

ABSTRACT

Abstract This research aimed to conduct a systematic review and metanalysis to compare the frequency of cell damage in crack users and nonusers, through Micronucleous (MN) test in buccal mucosa cells. A comprehensive search was carried out on MEDLINE via PubMeb, Web of Science, LILACS and the grey literature without restrictions. It was included case-control studies that report the frequency of micronuclei in the oral mucosa of adult crack users and nonusers. A review protocol was registered with PROSPERO (CRD42018115672), and conducted in accordance with the PRISMA guidelines for the report of this systematic review. Furthermore, study quality was evaluated using an adapted Newcastle-Ottawa Scale for cross-sectional studies.The original search yielded 27 references, after eligibility criteriaonly five articles were included. The number of micronuclei was higher in crack users compared to nonusers. Also, secondary outcomes: binucleated cells, nuclear buds, pyknosis, karyorrhexis and karyolysis had higher prevalence in crack users.Crack use is associated with genotoxic and mutagenic effects because there is a higher frequency of micronuclei in exfoliated cells of crack users. In addition, MN test proved to be a goodbiomarker to assess the mutagenic impact of crack use in oral epithelium.


Resumen Esta investigación tuvo como objetivo realizar una revisión sistemática y un meta-análisis para comparar la frecuencia de daño celular en usuarios de crack y sin crack, a través de la prueba de micronúcleos (MN) en células de la mucosa bucal. Se realizó una búsqueda exhaustiva en MEDLINE a través de PubMeb, Web of Science, LILACS y la literatura gris sin restricciones. Se incluyeron estudios de casos y controles que informaron la frecuencia de micronúcleos en la mucosa oral de usuarios adultos de crack y sin crack. Se registró un protocolo de revisión con PROSPERO (CRD42018115672), y se realizó de acuerdo con las pautas de PRISMA para el informe de esta revisión sistemática. Además, la calidad del estudio se evaluó mediante una escala Newcastle-Ottawa adaptada para estudios transversales. La búsqueda original arrojó 27 referencias, después de los criterios de elegibilidad se incluyeron un total de cinco artículos. El número de micronúcleos fue mayor en los usuarios de crack en compa ración con los usuarios sin crack. Además, los resultados secundarios de células binucleadas, yemas nucleares, picnosis, cario- rrexis y cariólisis tuvieron una mayor prevalencia en los usuarios de crack. El uso de crack se asocia con efectos genotóxicos y mutagénicos porque hay una mayor frecuencia de micronúcleos en las células exfoliadas de los usuarios de crack. Además, la prueba de MN demostró ser un buen biomarcador para evaluar el impacto mutagénico del uso de crack en el epitelio oral.


Subject(s)
Humans , Adolescent , Adult , Young Adult , Crack Cocaine , Cocaine-Related Disorders/pathology , Mouth Mucosa/pathology , Micronucleus Tests/methods , Mutagens
18.
Rev. otorrinolaringol. cir. cabeza cuello ; 80(2): 166-171, jun. 2020. graf
Article in Spanish | LILACS | ID: biblio-1115831

ABSTRACT

El tumor glómico es una neoplasia vascular originada de las células del músculo liso del componente neuromioarterial, responsable del control del flujo sanguíneo microvascular. Representa el 1,6% de todos los tumores de tejidos blandos, localizándose principalmente en la zona subungüeal y clínicamente muy doloroso. Su diagnóstico puede ser tardío debido a su pequeño tamaño, manifestaciones clínicas inespecíficas y localizaciones anatómicas inusuales. El tratamiento principalmente es quirúrgico, el cual es curativo, permitiendo además la confirmación histopatológica. Se presenta el reporte de caso de una paciente de 13 años de edad con un tumor glómico de localización inusual en mucosa bucal.


The glomus tumor is a vascular neoplasm originating from smooth muscle cells of neuromyoarterial component, responsible for the control of microvascular blood flow. It represents 1.6% of all soft tissue tumors, being located mainly in the subungual area and clinically very painful. Diagnosis may be delayed because of their small size, nonspecific clinical manifestations and unusual anatomical locations. Treatment is primarily surgical, which is healing, also allowing the histopathologic confirmation. The case report of a 13-year-old patient with an unusual-located glomus tumor in the oral mucosa is presented.


Subject(s)
Humans , Female , Adolescent , Mouth Neoplasms/pathology , Glomus Tumor/pathology , Mouth Neoplasms/diagnosis , Glomus Tumor/diagnosis , Mouth Mucosa/pathology
19.
RFO UPF ; 25(1): 107-111, 20200430. ilus
Article in English | LILACS, BBO | ID: biblio-1357742

ABSTRACT

Introduction: sialolithiasis is the most common form of obstructive sialadenitis caused by a mixture of different calcium phosphates and an organic matrix. It is one of the most common salivary gland diseases, often attributed to the submandibular gland, with no relation to age or gender. However, it is rarely reported in the minor salivary glands. Objective: the present study aims to report auncommon clinical finding case of a sialolithiasisof minor salivary gland in labial mucosa. Case report: a 43-year-old female patient presented with a single, yellow and asymptomatic nodule in the labial mucosa at clinical examination. The clinical hypotheses were lipoma and fibrous hyperplasia. The lesion was biopsied, and the histopathological analysis showed a mineralized tissue. The final diagnosis was sialolithiasis and the patient remained under follow-up (8 months) without relapse. Conclusion: this case shows that sialolithiasis should be included in the diagnostic hypotheses when occur in a minor salivary glands area and emphasizes the importance of a complete clinical examination since it was not complaint of the patient.(AU)


Introdução: a sialolitíase é a forma mais comum de sialadenite obstrutiva causada por um composto de diferentes produtos, como fosfato de cálcio e matriz orgânica. É uma das doenças mais comuns das glândulas salivares, geralmente atribuídas à glândula submandibular, sem relação com idade ou sexo. No entanto, raramente é relatada nas glândulas salivares menores. Objetivo: reportar um achado clínico incomum de sialolitíase em glândula oral menor na mucosa labial. Relato de caso: uma paciente do sexo feminino, de 43 anos, apresentou nódulo único, amarelo e assintomático na mucosa labial durante o exame clínico. As hipóteses clínicas foram lipoma e hiperplasia fibrosa. A lesão foi encaminhada para biópsia e a análise histopatológica mostrou um tecido mineralizado. O diagnóstico final foi de sialolitíase e o paciente permaneceu em acompanhamento por 8 meses sem recidiva. Conclusão: este caso mostra que a sialolitíase deve ser incluída nas hipóteses diagnósticas de lesões em áreas de glândulas salivares menores e enfatiza a importância de um exame clínico completo, pois não se tratava da queixa principal da paciente.(AU)


Subject(s)
Humans , Female , Adult , Salivary Glands, Minor/pathology , Salivary Gland Calculi/pathology , Mouth Mucosa/pathology , Biopsy , Rare Diseases
20.
Rev. Asoc. Odontol. Argent ; 108(1): 14-18, ene.-abr. 2020. ilus
Article in Spanish | LILACS | ID: biblio-1096370

ABSTRACT

Los lipomas son tumores benignos compuestos por adipocitos maduros. Si bien representan la neoplasia más común en el cuerpo humano, su aparición en la región de la cabeza y el cuello es relativamente rara. No muestra predilección por sexo y afecta a individuos en la cuarta década de vida. Clínicamente, puede observarse un aumento de volumen nodular, de consistencia blanda y superficie lisa. Su etiopatogenia aún es desconocida, aunque algunos autores han sugerido factores endócrinos, inflamatorios, hereditarios y traumáticos. El diagnóstico se realiza a través de la evaluación clínica, con la ayuda de pruebas de imagen como la tomografía computarizada y la resonancia magnética. Sin embargo, solo puede ser confirmado mediante análisis histopatológico de la lesión, considerado el examen por excelencia. El tratamiento de los lipomas y todas sus variantes consiste en la extirpación quirúrgica total, con lo cual se disminuye la posibilidad de recidivas, que es rara de por sí. El objetivo de esta publicación es informar un caso clínico de lipoma localizado en la región de la mucosa yugal, con extirpación quirúrgica completa de la lesión de manera ambulatoria (AU)


Lipomas are benign tumors composed of mature adipo- cytes. Although they represent the most common neoplasia in the human body, their occurrence in the head and neck region is relatively rare. Regardless of gender, they affect individu- als from the fourth decade of life on. Clinically, an increase of the nodular volume with softened consistency and smooth surface can be observed. Although its etiopathogenesis is still uncertain, some authors have suggested endocrinal, inflam- matory, hereditary and traumatic factors. The diagnosis is made through clinical evaluation, with the aid of imaging ex- aminations, such as computerized tomography and magnetic resonance. However, it can only be confirmed through the histopathological analysis of the lesion, which is considered the gold standard examination. The treatment of the lipomas and all their variations consists of complete surgical exci- sion, thus diminishing the possibility of recurrence, which in turn is rare. The aim of this publication is to report a clin- ical case of lipoma, located in the jugal mucosa region and treated through complete surgical removal of the lesion on an outpatient basis (AU)


Subject(s)
Humans , Female , Middle Aged , Neoplasms, Adipose Tissue , Lipoma/surgery , Lipoma/diagnostic imaging , Mouth Mucosa/pathology , Brazil , Histological Techniques , Oral Surgical Procedures , Ambulatory Surgical Procedures
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