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1.
Braz. j. oral sci ; 20: e219638, jan.-dez. 2021. tab
Article in English | LILACS, BBO | ID: biblio-1254752

ABSTRACT

Diagnosis of oral and oropharyngeal cancer in advanced stages may be associated with social nature factors, access to health care, education, occupation, and behavioral/ cultural factors. Aim: To determine the factors related to high clinical-staging in patients diagnosed with squamous cell carcinoma in the oral and oropharyngeal region in a Cancer Center in Brazil between 2009 and 2015. Methods: It is an epidemiological, retrospective, and exploratory study. Patients diagnosed with squamous cell carcinoma had their medical records analyzed. The variables considered were sociodemographic, lifestyle, and disease characteristics. Descriptive and exploratory tests (Pearson's, chi-square test and, Student's t-test) were realized. Results: We analyzed 365 patient records, among which 289 (79.17%) were male, and 73 (20.0%) were female. Age ranged from 16 to 101 years, with a mean of 61.13. Regarding education, 157 (43.01%) studied < 8 years, 103 (28.21%) were illiterate and 102 (27.94%) studied > 8 years. 305 (83.56%) patients live in urban areas. There was an association between high clinical-staging and low educational level. For high clinical-staging, symptomatology, tobacco, and alcohol intake as well. Conclusion: Patients with low educational levels tend to report the disease later, and their diagnostics occurred in advanced stages. Thus, specific public health policies for this population, including access to dental care to recognize the clinical signs and early diagnosis, are necessary


Subject(s)
Socioeconomic Factors , Mouth Neoplasms/diagnosis , Oropharyngeal Neoplasms/diagnosis , Medical Records
2.
Rev. Soc. Odontol. La Plata ; 31(60): 23-26, jul. 2021. ilus
Article in Spanish | LILACS | ID: biblio-1284468

ABSTRACT

Las neoplasias malignas de la cavidad oral en gran medida (90%) consisten en carcinoma de células escamosas que surgen de la mucosa de revestimiento. El 10% restantes de neoplasias malignas orales de un grupo heterogéneo de tumores de diferente etiología. Presentamos dos casos de patología oncohematológica: Mieloma Múltiple (AU)


Malignant neoplasms of the oral cavity largely (90%) consist of squamous cell carcinoma arising from the lining mucosa. e remaining 10% of oral malignancies from a heterogeneous group of tumors of different etiology. We present two cases of oncohematological pathology: Multiple Myeloma (AU)


Subject(s)
Humans , Male , Middle Aged , Plasmacytoma/diagnosis , Plasmacytoma/pathology , Plasmacytoma/diagnostic imaging , Mouth Neoplasms/diagnosis , Radiotherapy , Biopsy/methods , Tomography, X-Ray Computed , Oral Surgical Procedures/methods , Diphosphonates/therapeutic use , Maxillary Sinus/surgery , Multiple Myeloma
3.
Article in English | WPRIM | ID: wpr-921379

ABSTRACT

OBJECTIVES@#This study aims to investigate the diagnostic value of peripheral blood circulating tumor cells (CTCs) in oral squamous cell carcinoma (OSCC) and its correlation with the clinicopathological features of OSCC.@*METHODS@#Ninety-three patients diagnosed as OSCC in the First Affiliated Hospital of Zhengzhou University from May 2019 to May 2020 were selected as the experimental group, and 20 healthy volunteers were employed as the control group. The CTCs value of peripheral blood of the patients were measured by CTCs detection technology, and its clinical significance was analyzed.@*RESULTS@#The CTCs values in the experimental group were higher than those in the control group, and the difference was statistically significant (@*CONCLUSIONS@#Peripheral blood CTCs has important clinical value for early screening, auxiliary diagnosis, evaluation of metastasis, and determination of malignant degree, progression, and pathological grade of OSCC and a relatively reliable tumor detection indicator.


Subject(s)
Carcinoma, Squamous Cell/diagnosis , Head and Neck Neoplasms , Humans , Mouth Neoplasms/diagnosis , Neoplastic Cells, Circulating , Squamous Cell Carcinoma of Head and Neck
4.
Braz. j. med. biol. res ; 54(3): e10504, 2021. tab, graf
Article in English | LILACS | ID: biblio-1153517

ABSTRACT

Molecular changes that affect mitochondrial glycolysis have been associated with the maintenance of tumor cells. Some metabolic factors have already been described as predictors of disease severity and outcomes. This systematic review was conducted to answer the question: Is the glycolytic pathway correlated with the prognosis of oral squamous cell carcinoma (OSCC)? A search strategy was developed to retrieve studies in English from PubMed, Scopus, and ISI Web of Science using keywords related to squamous cell carcinoma, survival, and glycolytic pathway, with no restriction of publication date. The search retrieved 1273 publications. After the titles and abstracts were analyzed, 27 studies met inclusion criteria. Studies were divided into groups according to two subtopics, glycolytic pathways and diagnosis, which describe the glycolytic profile of OSCC tumors. Several components of tumor energy metabolism found in this review are important predictors of survival of patients with OSCC.


Subject(s)
Humans , Mouth Neoplasms/diagnosis , Squamous Cell Carcinoma of Head and Neck/diagnosis , Glycolysis , Mouth Neoplasms/metabolism , Positron Emission Tomography Computed Tomography , Squamous Cell Carcinoma of Head and Neck/metabolism
5.
J. oral res. (Impresa) ; 9(6): 516-521, dic. 31, 2020. ilus, tab
Article in English | LILACS | ID: biblio-1178950

ABSTRACT

Peripheral T-Cell Lymphoma Not Otherwise Specified it is a rare type of Non-Hodgkin t-cells malignant tumor whose oral manifestations are difficult to diagnose. A case of a 48-year-old male with a hemi-maxillary lesion histological and immunohistochemically compatible with Peripheral T-Cell Lymphoma not otherwise specified is presented. A case of a 48-year-old male with a hemi-maxillary lesion histological and immunohistochemically compatible with Peripheral T-Cell Lymphoma not otherwise specified is presented. The patient treatment consisted of chemotherapy, but after the second cycle, died from immunosuppressive complications. Early stage diagnosis of oral lesions is imperative to avoid aggressive treatment and low overall survival rate of such pathologies.


Introducción: El linfoma periférico de células T no especificado es un tipo raro de tumor maligno no Hodgkin de células T cuyas manifestaciones orales son difíciles de diagnosticar. Se presenta el caso de un varón de 48 años con lesión hemimaxilar histológica e inmunohistoquímicamente compatible con linfoma periférico de células T no especificado. El tratamiento del paciente consistió en quimioterapia, pero después del segundo ciclo, falleció por complicaciones inmunosupresoras. El diagnóstico temprano de las lesiones orales es imperativo para evitar un tratamiento agresivo y la baja tasa de supervivencia.


Subject(s)
Humans , Male , Middle Aged , Mouth Neoplasms/diagnosis , Mouth Neoplasms/therapy , Lymphoma, T-Cell, Peripheral/diagnosis , Lymphoma, T-Cell, Peripheral/therapy , Antineoplastic Combined Chemotherapy Protocols , Early Diagnosis , Drug Therapy
6.
Rev. medica electron ; 42(5): 2378-2387, sept.-oct. 2020. graf
Article in Spanish | LILACS, CUMED | ID: biblio-1144741

ABSTRACT

RESUMEN El linfoma de Burkitt, se trata de un subtipo poco frecuente del linfoma no Hodgkin, con elevada frecuencia en aquellos pacientes con sida. La hepatoesplenomegalia es un signo clínico de gran importancia para el diagnóstico oportuno de algunas patologías; entre los mecanismos de formación de la hepatoesplenomegalia se encuentra la infiltración celular, ocasionada por la migración de células tumorales. Se presenta por inflamaciones debido a la presencia de infecciones por virus o bacterias las cuales son muy comunes en pacientes con sida. Se presentó un caso de un paciente masculino de 4 años, diagnosticado con VIH positivo, con la configuración correspondiente de criterios clínicos en clasificación C para sida. El cual desarrolló a nivel de cavidad oral un Burkitt primario, que se acompañó de hepatoesplenomegalia. Se pretendió describir la relación y el comportamiento de este tipo de linfoma con la hepatoesplenomegalia, así como la repercusión a nivel del sistema estomatognático, a nivel sistémico y el plan de tratamiento. Por el cuadro clínico e inmunológico del paciente estudiado, se planteó un pronóstico reservado por presentar un cuadro clínico infrecuente, en el que se observó Burkitt; tanto a nivel del sistema estomatognático como a nivel abdominal. Se hizo necesario realizar un diagnóstico oportuno y certero para iniciar el tratamiento a tiempo, se comenzó inmediatamente con tratamiento (AU).


ABSTRACT Burkitt lymphoma (BL) is a rare subtype of non-Hodgkin lymphoma, with high frequency in those patients with AIDS. Hepatosplenomegaly is a clinical sign of great importance for the timely diagnosis of some pathologies; cellular infiltration is found among the mechanisms of hepatosplenomegaly formation; it is caused by the migration of tumor cells. It emerges by inflammations due to the presence of infections by virus or bacteria which are very common in patients with AIDS. The authors present the case of a male patient, aged 4 years, with a positive HIV diagnosis, and the correspondent configuration of clinical criteria in C classification for AIDS, who developed a primary Burkitt lymphoma at the level of oral cavity We present the case of a 4-year-old male patient diagnosed with HIV positive, with the corresponding configuration of clinical criteria in classification C for AIDS; who developed a primary LB at the oral cavity level that was accompanied by hepatosplenomegaly. The authors pretended to describe the relation and behavior of this kind of lymphoma with hepatosplenomegaly, and also the repercussion at the stomatognathic level, at the systemic level and the treatment plan. Due to the clinical and immunological characteristics of the studied patient a reserved prognosis was given because of presenting infrequent clinical characteristics in which a Burkitt was observed both, at the stomatognathic and at the abdominal level. It was necessary to make an opportune and accurate diagnosis to begin the treatment on time (AU).


Subject(s)
Humans , Male , Child , Signs and Symptoms , Child , Burkitt Lymphoma/complications , Splenomegaly/complications , Splenomegaly/diagnosis , Mouth Neoplasms/complications , Mouth Neoplasms/diagnosis , HIV Antigens/therapeutic use , Clinical Diagnosis/diagnosis , HIV/pathogenicity , Hepatomegaly/diagnosis
7.
Rev. Odontol. Araçatuba (Impr.) ; 41(2): 40-44, maio-ago.2020. tab, graf
Article in Portuguese | LILACS, BBO | ID: biblio-1102694

ABSTRACT

O objetivo deste estudo foi avaliar o conhecimento de pacientes do Centro Universitário da Serra Gaúcha acerca do câncer oral. Foram aplicados questionários para idosos (n=60) de ambos os gêneros, diferentes etnias e graus de escolaridade. A análise dos dados foi realizada por meio do teste qui-quadrado com nível de confiança de 95%. Não houve relação estatisticamente significativa (p>0,05) entre gênero, estado civil e escolaridade. A presença de lesões bucais, ausência de dentes, visitas frequentes ao dentista, e uso de bebida alcoólica e tabagismo não influenciaram quanto ao conhecimento acerca do câncer bucal. Embora a maioria dos pacientes (85%) já tenha ouvido falar em câncer bucal, apenas a minoria relatou saber se prevenir (23%) e possuir o hábito de examinar a boca em casa (35%). Além disso, apesar de 55% dos pacientes visitarem regularmente o dentista, apenas 28,3% relatou ter recebido informações sobre o câncer bucal. Pôde-se concluir que mesmo sabendo da existência do câncer bucal, a população idosa não possui informações suficientes para o correto diagnóstico e prevenção da doença, sendo necessário melhorias nas orientações fornecidas pelos profissionais da área da saúde com relação a este tema(AU)


The aim of this study was to evaluate the knowledge of patients at Serra Gaucha University Center about oral cancer. Questionnaires were applied to the elderly (n = 60) of both genders, different ethnicities and educational levels. Data analysis was performed using the chi-square test with a 95% confidence level. There was no statistically significant relationship (p> 0.05) between gender, marital status and education. The presence of oral lesions, absence of teeth, frequent visits to the dentist, and the use of alcohol and smoking did not influence the knowledge about oral cancer. Although most patients (85%) have heard of oral cancer, only a minority reported knowing whether to prevent it (23%) and having the habit of examining their mouth at home (35%). In addition, although 55% of patients regularly visit the dentist, only 28.3% reported receiving oral cancer information. It can be concluded that even knowing the existence of oral cancer, the elderly population does not have enough information for the correct diagnosis and prevention of the disease, being necessary improvements in the guidance provided by health professionals regarding this theme(AU)


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Mouth Neoplasms , Mouth Neoplasms/diagnosis , Mouth Neoplasms/prevention & control , Health of the Elderly
8.
Int. j. odontostomatol. (Print) ; 14(2): 172-176, June 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1090671

ABSTRACT

El objetivo de este estudio es determinar la prevalencia de lesiones orales malignas y potencialmente malignas (LPM) en funcionarios de la Universidad de Valparaíso y de Viña del Mar durante los años 2016 - 2017. Fueron citados 161 funcionarios, quienes accedieron a una encuesta que evaluaba factores de riesgo de cáncer oral (tabaco y alcohol) y si habían escuchado de la patología, sumado a un examen clínico. De los pacientes examinados, se diagnosticaron 121 lesiones de las cuales 2 fueron diagnosticadas como lesiones potencialmente malignas: Liquen plano y Leucoplasia, con una prevalencia de 1,7 %. El 50,3 % de los pacientes sabía de la existencia de cáncer oral. El Screening es una medida que permite dar a conocer a la población la existencia de cáncer oral y alertarlos sobre la importancia de su examen para su identificación de manera temprana.


The objective of this study is to determine the prevalence of malignant and potentially malignant oral lesions (PML) in University of Valparaíso and Viña del Mar employees, during the years 2016 - 2017. We cited 161 employees, who accessed a survey evaluating risk factors for oral cancer (tobacco and alcohol) and if they had heard of the disease. In addition, a clinical examination was carried out. Of the patients examined, 121 lesions were diagnosed, of which 2 were diagnosed as potentially malignant lesions: Lichen planus and Leukoplakia, with a prevalence of 1.6 %. 50.3 % of patients knew of the existence of oral cancer. Epidemiological designs are needed to better establish causality between risk factors and malignant or, potentially malignant lesions.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Precancerous Conditions/epidemiology , Mouth Neoplasms/epidemiology , Mass Screening/methods , Precancerous Conditions/diagnosis , Alcohol Drinking , Mouth Neoplasms/diagnosis , Health Behavior , Epidemiology, Descriptive , Prevalence , Cross-Sectional Studies , Risk Factors , Early Detection of Cancer/methods , Tobacco Use
9.
Rev. otorrinolaringol. cir. cabeza cuello ; 80(2): 166-171, jun. 2020. graf
Article in Spanish | LILACS | ID: biblio-1115831

ABSTRACT

El tumor glómico es una neoplasia vascular originada de las células del músculo liso del componente neuromioarterial, responsable del control del flujo sanguíneo microvascular. Representa el 1,6% de todos los tumores de tejidos blandos, localizándose principalmente en la zona subungüeal y clínicamente muy doloroso. Su diagnóstico puede ser tardío debido a su pequeño tamaño, manifestaciones clínicas inespecíficas y localizaciones anatómicas inusuales. El tratamiento principalmente es quirúrgico, el cual es curativo, permitiendo además la confirmación histopatológica. Se presenta el reporte de caso de una paciente de 13 años de edad con un tumor glómico de localización inusual en mucosa bucal.


The glomus tumor is a vascular neoplasm originating from smooth muscle cells of neuromyoarterial component, responsible for the control of microvascular blood flow. It represents 1.6% of all soft tissue tumors, being located mainly in the subungual area and clinically very painful. Diagnosis may be delayed because of their small size, nonspecific clinical manifestations and unusual anatomical locations. Treatment is primarily surgical, which is healing, also allowing the histopathologic confirmation. The case report of a 13-year-old patient with an unusual-located glomus tumor in the oral mucosa is presented.


Subject(s)
Humans , Female , Adolescent , Mouth Neoplasms/pathology , Glomus Tumor/pathology , Mouth Neoplasms/diagnosis , Glomus Tumor/diagnosis , Mouth Mucosa/pathology
10.
Rev. cuba. med. mil ; 49(1): e280, ene.-mar. 2020. fig
Article in Spanish | LILACS, CUMED | ID: biblio-1126681

ABSTRACT

Introducción: El tabaquismo es una enfermedad adictiva crónica la cual constituye la causa de muerte prevenible más importante en los países desarrollados y la de mayor morbilidad y mortalidad antes que cualquier otra enfermedad crónica (hipertensión arterial, diabetes mellitus). Se considera una epidemia de carácter universal y es una gravosa carga para el individuo, la familia y la sociedad. Objetivo: Determinar el nivel de conocimientos sobre el hábito de fumar, relacionado con la cavidad bucal en adultos fumadores. Métodos: Se realizó un estudio descriptivo transversal con 55 pacientes fumadores de ambos sexos. Se aplicó un cuestionario para realizar un diagnóstico de conocimientos sobre el daño que ocasiona el tabaquismo en la cavidad bucal. Resultados: El 76,33 por ciento de los sujetos presentaron un nivel de conocimiento insuficiente, el 92,72 por ciento conocían la relación con el cáncer bucal, el 72,72 por ciento los beneficios de abandonar el hábito y el 53,36 por ciento la relación con los dientes, sin embargo el 83,63 por ciento presentó un nivel de conocimiento insuficiente en relación con los tejidos periodontales. Conclusiones: El nivel de conocimientos en la población estudiada fue insuficiente(AU)


Introduction: Smoking is a chronic addictive disease which is the most important preventable cause of death in developed countries and the one with the highest morbidity and mortality before any other chronic disease (hypertension, diabetes mellitus). It is considered an epidemic of universal character and is a burden for the individual, the family and society. Objective: To determine the level of knowledge about smoking habit, related to the oral cavity in adult smokers. Methods: A cross-sectional descriptive study was conducted with 55 smokers patients of both sexes. A questionnaire was applied to make a diagnosis of knowledge about the damage caused by smoking in the oral cavity. Results: 76.33 percent of the subjects presented an insufficient level of knowledge, 92.72 percent knew the relationship with oral cancer, 72.72 percent the benefits of quitting and 53.36 percent the relationship with teeth, however, 83.63 percent presented an insufficient level of knowledge in relation to periodontal tissues. Conclusions: The level of knowledge in the population studied was insufficient(AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Tobacco Use Disorder/complications , Mouth Neoplasms/diagnosis , Chronic Disease/prevention & control , Surveys and Questionnaires , Knowledge , Epidemiology, Descriptive , Cross-Sectional Studies
11.
Medwave ; 20(5): e7938, 2020.
Article in English, Spanish | LILACS | ID: biblio-1116885

ABSTRACT

INTRODUCCIÓN: El cáncer oral tiene una tasa de supervivencia a los cinco años de 50%, debido a que frecuentemente su diagnóstico es realizado en estadios avanzados. Por lo tanto, son necesarias nuevas ayudas diagnósticas. Actualmente, existe un número significativo de publicaciones científicas sugiriendo el uso de biomarcadores salivales para el diagnóstico de cáncer oral. Sin embargo, son desconocidas las propiedades diagnósticas de estos biomarcadores. El objetivo de esta revisión sistemática es evaluar la evidencia sobre la precisión diagnóstica de biomarcadores salivales usados en la identificación de cáncer oral y desórdenes potencialmente malignos. MÉTODOS: Este protocolo es reportado en concordancia con el Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P). Se incluirán estudios evaluando la precisión diagnóstica de biomarcadores salivales para cáncer oral y desórdenes potencialmente malignos. Estos deberán reportar sensibilidad y especificidad, y utilizar como estándar de referencia un diagnóstico histopatológico. Se realizará una búsqueda en MEDLINE, EMBASE, Cochrane Library y literatura gris. Dos autores independientemente seleccionarán los estudios y extraerán los datos. La calidad metodológica de los estudios será determinada usando The Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2). RESULTADOS ESPERADOS Y CONCLUSIÓN: Los hallazgos de esta revisión sistemática proporcionarán información acerca de la precisión diagnóstica de los biomarcadores salivales para diagnóstico de cáncer oral y desórdenes potencialmente malignos.


INTRODUCTION: Oral cancer has a 5-year survival rate of 50% because diagnosis is commonly performed at an advanced stage of the disease, so new diagnostic tools are needed. Nowadays, there is a vast number of publications suggesting the use of salivary biomarkers for oral cancer and potentially malignant disorders diagnosis, but their diagnostic accuracy is unclear. Thus, the goal of this systematic review is to evaluate the diagnostic accuracy of salivary biomarkers for oral cancer and potentially malignant disorders. METHODS: This protocol is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P). We will include primary studies assessing the diagnostic accuracy of salivary biomarkers for oral cancer and potentially malignant disorders. Studies must report data about sensitivity and specificity; gold standard must be the histopathology diagnosis. We will search MEDLINE, EMBASE, the Cochrane Library, and gray literature. Two authors will independently select the studies and extract the data. The methodology quality of studies will be determined using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2). EXPECTED RESULTS AND CONCLUSION: Our findings will provide information about the diagnostic accuracy of salivary biomarkers for oral cancer and potentially malignant disorders.


Subject(s)
Humans , Saliva/metabolism , Mouth Neoplasms/diagnosis , Biomarkers/analysis , Research Design , Mouth Neoplasms/mortality , Sensitivity and Specificity
12.
Rev. Ciênc. Plur ; 6(3): 137-153, 2020. tab
Article in Portuguese | LILACS, BBO | ID: biblio-1128105

ABSTRACT

IntroduçãoO câncer de boca é uma neoplasia maligna que representa um sério problema de saúde pública devido alta incidência, prevalência,mortalidade e o cirurgião-dentista deve estar apto a diagnosticar essa doença.Objetivo:Esseestudo buscou avaliar o conhecimento dos cirurgiões-dentistas da Estratégia de Saúde da Família de Mossoró, estado do Rio Grande do Nortesobre o câncer bucal. Metodologia: Para a coleta de dados, o pesquisador se deslocou à Unidade Básica de Saúde para convidar o profissional a participar da pesquisa e aplicou um questionário estruturado. Após análise dos questionários, foi atribuído um conceito a cada entrevistado para avaliação do seu conhecimento sobre o câncer de boca.Para tabulação e análise dos dados, foi utilizado o programa estatístico Statiscal Package Social Sciences, versão 23.0. A associação entre as variáveis foi verificada por meio do teste qui-quadrado.Resultados: Em relação à autoavaliação, apenas 7% da amostra considerou-se com nível ótimo de conhecimento.Uma minoria (4,7%) participou de cursos com essa temática no ano passado. Observou-se, ainda, que 81,4% dos cirurgiões-dentistas apresentaram baixo nível de confiança para realizar procedimentos de diagnóstico do câncer bucal. Ao atribuir conceitos de acordo com as respostas dosprofissionais sobre o conhecimento do câncer bucal, constatou-se quemaior parte dos cirurgiões-dentistas entrevistados obtiveram conceito regular (C) e bom (B) sobre o câncer de boca. Após análise estatística, observou-seque quanto maior a faixa etária, maior o percentual de profissionais com conhecimento regular e insatisfatório sobre o câncer de boca, sendo este resultado estatisticamente significativo. Conclusões:A maior parte dos cirurgiões-dentistas de Mossoró apresentaram conhecimento entre regular e bom sobre o câncer de boca, euma parcela expressiva se autodeclara insegura para realizar o diagnóstico, sendo necessáriostreinamentos sobre o câncer de boca e atualizações que também contribuam com a elevação da autoconfiança desses profissionais (AU).


Introduction:Oral cancer is a malignant neoplasm that represents a serious public health problem due to the high incidence, prevalence and mortality and the dentist must be able to diagnose this disease. Objective: This study aimed to evaluate the knowledge of dentists of the Family Health Strategy of Mossoró (Rio Grande do Norte, Brazil) about oral cancer. Methodology:The researcher went to the Basic Health Unit to invite dentists to participate in the research andapplied a structured questionnaire. After analyzing the questionnaires, each interviewee was given a concept to assess their knowledge of oral cancer. The tabulation and data analysis was used with a statistical program called Statiscal Package Social Sciences, version 23.0. The association between variables was analysed using qui-square test.Results:Regarding self-assessment, only 7% of the sample considered themselves to have an excellent level of knowledge about the disease. A minority (4.7%) participated in courses with this theme last year. It was also observed that 81.4% of dentists had a low level of confidence in performing oral cancer diagnostic procedures. When assigning concepts according to the answers given by professionals about the knowledge of oral cancer, it was found that most of the interviewed dental surgeons obtained a regular (C) and good (B) concept of oral cancer. After statistical analysis, it was possible to observe that the older the age group, the higher the percentage of professionals with regular and unsatisfactory knowdge about oral cancer, this result being statistically significant.Conclusions:Most of the dentists in Mossoró had knowledge between regular and good about oral cancer, andthey feel insecure to make the diagnosis, requiring training on oral cancer and refresher courses that also contribute to the increase of self-confidence of these professionals (AU).


Introducción: El cáncer de boca es un grave problema de salud pública debido a la alta incidencia, prevalencia y mortalidad, y eldentista debe diagnosticar esta enfermedad. Objetivo: El objetivo del estudio fueevaluar el conocimiento de los dentistas de la Estrategia de Salud Familiar de Mossoró(Rio Grande do Norte, Brasil) sobre el cáncer bucal. Metodología: Para la recolección de datos, el investigador se trasladó a la Unidad Básica de Salud para invitar a los profesionales y se aplicó un cuestionario estructurado. Después de analizar los cuestionarios, a cada entrevistado se le dio una puntuación para evaluar su conocimiento sobre el cáncer bucal. Para análisis de datos, se utilizó el programa Statiscal Package Social Sciencesversión 23.0. La asociación entre variables se verificó mediante la prueba de chi-cuadrado. Resultados: Con respecto a la autoevaluación, 7% de la muestra se consideraba que tenía un excelente nivel de conocimiento sobre la enfermedad. Una minoría (4.7%) participó en cursos respecto a este tema el año pasado. 81,4% de los dentistas tenían un bajo nivel de confianza para realizar procedimientos de diagnóstico de cáncer bucal. Al asignar puntuaciones según las respuestas dadas por los profesionales, se descubrió que la mayoría de los dentistas entrevistados obtuvieron una puntuación regular (C) y buena (B) sobre el cáncer bucal. Después del análisis estadístico, fue posible observar que cuanto mayor es el grupo de edad, mayor es el porcentaje de profesionales con conocimiento regular e insatisfactorio sobre el cáncer bucal, y este resultado es estadísticamente significativo.Conclusiones: La mayoría de los dentistas en Mossoró presentaron un conocimiento entre regular y bueno sobre el cáncer bucalyuna parte significativa se autodeclaróinsegura para hacer el diagnóstico, siendo necesarias capacitaciones sobre cáncer bucal y cursos de actualización paraaumentarla autoconfianza de estos profesionales.Palabras clave:Cáncer bucal. Atención Primaria en Salud. Cirujano dentista (AU).


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Brazil , Mouth Neoplasms/diagnosis , Mouth Neoplasms/pathology , Family Health Strategy , Dentists , Primary Health Care , Chi-Square Distribution , Surveys and Questionnaires
13.
J. oral res. (Impresa) ; 8(4): 290-296, nov. 5, 2019. tab
Article in English | LILACS | ID: biblio-1145350

ABSTRACT

Objective: To determine the level of knowledge of Oral Cancer (OC) of dental surgeons in Los Rios Region in the year 2017. Materials and methods: A descriptive, cross-sectional study consisting of a survey containing 24 multiple-choice questions was conducted and applied in person to 102 public practice dentists of Los Ríos Region, between March-July 2017. Participants were previously informed that the survey was voluntary, anonymous and confidential. Characterization data from the population was collected and the variable "Knowledge of Oral Cancer" along with its subsections on OC epidemiology, etiopathogenesis, diagnosis, treatment/complications and prognosis/prevention were measured. Tabulated data were analyzed through descriptive statistics. Results were presented through a passing percentage (60% minimum for approval). Results: 100 surveys were answered (with a 98% response rate). Knowledge of OC averaged a 77% passing rate among the participants: 63% for the epidemiology section, 78% for etiopathogenesis, 86.5% for diagnosis, 64% for treatment/complications, while OC prevention resulted in a 75% passing rate. Conclusion: A high percentage of dental surgeons in Los Rios Region demonstrated a satisfactory knowledge of the etiopathogenesis, diagnosis and prevention of OC. However, a low percentage responded correctly regarding the epidemiological factors, treatment and complications. It is highly recommended to follow the same research methodology in other regions across Chile in order to analyze results at a national level with a new approach, so as to properly guide future professional training programs.


Objetivo: Determinar los conocimientos acerca de cáncer oral (CO) que poseen los odontólogos de la Región de los Ríos en el año 2017. Material y métodos: Se realizó un estudio descriptivo mediante encuestas de preguntas de selección múltiple aplicadas a 102 odontólogos de práctica pública de la Región de los Ríos. Se informó previamente a los participantes el carácter voluntario, anónimo y confidencial de la encuesta y se entregó un consentimiento informado. Se recopilaron datos de caracterización de la población y se midió la variable "Conocimientos acerca del Cáncer Oral" en sus dimensiones de epidemiología, etiopatogenia, diagnóstico, tratamiento/complicaciones y pronóstico/prevención. A los datos tabulados se les realizó estadística descriptiva. Los resultados se presentaron mediante porcentaje de aprobación y nota equivalente al 60% en escala continua. Resultados: Se respondieron 100 encuestas (tasa de respuesta del 98%). El Conocimiento acerca de CO promedió una aprobación de 77% entre los participantes, equivalente a una nota 5,29. La dimensión de epidemiología alcanzó un 63%, etiopatogenia un 78%, diagnóstico un 86,5%, tratamiento/complicaciones un 64% y prevención 75% de aprobación. Conclusión: Un alto porcentaje de los cirujanos dentistas de la Región de los Ríos demostró conocimientos adecuados acerca de la etiopatogenia, diagnóstico y prevención del CO. Sin embargo, un bajo porcentaje respondió asertivamente en lo que respecta a factores epidemiológicos, tratamiento y complicaciones. Se sugiere seguir la misma línea investigativa en otras regiones, para analizar resultados a nivel nacional y orientar, con un nuevo enfoque, los programas educativos para profesionales.


Subject(s)
Humans , Male , Female , Mouth Neoplasms/diagnosis , Practice Patterns, Dentists' , Dentists , Chile , Epidemiology, Descriptive , Surveys and Questionnaires , Early Detection of Cancer
14.
Buenos Aires; GCBA. Gerencia Operativa de Epidemiología; 15 Marzo 2019. a) f: 12 l:15 p. graf.(Boletín Epidemiológico Semanal: Ciudad Autónoma de Buenos Aires, 4, 134).
Monography in Spanish | LILACS, InstitutionalDB, BINACIS, UNISALUD | ID: biblio-1102823

ABSTRACT

Desde la Subgerencia Operativa Red de Odontología en Hospitales, dependiente de la Dirección General de Hospitales del Ministerio de Salud del GCABA, conjuntamente con la Dirección Nacional de Salud Bucodental de la Secretaria de Salud de la Nación, y la Facultad de Odontología de la UBA, se realizaron diversas actividades de Promoción y Prevención del Cáncer Bucal promoviendo el diagnóstico precoz, las medidas de prevención y de control de esta patología. Se informa sobre los resultados de población encuestada, factores de riesgo y género, uso de protección solar, y consumo de bebidas.


Subject(s)
Mouth Neoplasms/diagnosis , Mouth Neoplasms/etiology , Mouth Neoplasms/prevention & control , Mouth Neoplasms/epidemiology , Oral Health , Public Health Dentistry , Health Promotion/supply & distribution
15.
Pesqui. bras. odontopediatria clín. integr ; 19(1): 4344, 01 Fevereiro 2019. tab
Article in English | LILACS, BBO | ID: biblio-997890

ABSTRACT

Objective: To determine compatibility between clinical diagnosis and the pathological reports of biopsies from oral lesions. Material and Methods: In this descriptive study, 1146 clinical files of patients referring to Tabriz Faculty of Dentistry from 2004 to 2016 were retrieved and evaluated. The kappa coefficient was calculated for each file for compatibility of clinical and pathological diagnosis. Results: In relation to clinical (40.2%) and pathological (39.2%) diagnosis, irritational lesions of soft tissues exhibited the highest frequency. In 72.3% of cases, the clinical and pathological diagnosis were compatible and in 27.7% of cases these diagnosis were not compatible. The highest compatibility rates were detected for irritational lesions of soft tissues (81.5%) and mucocutaneous lesions (76.9%). There was no compatibility for osseous malignant tumors, inflammatory tissues, granulation tissues, metastatic lesions and hematologic disorders. Conclusion: Approximately one-third of clinical and histopathological diagnosis were not compatible. Therefore, to reach a correct diagnosis, the clinical, radiographic and histopathological views should be evaluated simultaneously.


Subject(s)
Humans , Mouth Neoplasms/diagnosis , Clinical Diagnosis/diagnosis , Clinical Laboratory Techniques/methods , Diagnosis, Oral , Iran , Medical Records , Epidemiology, Descriptive , Data Interpretation, Statistical
16.
Pesqui. bras. odontopediatria clín. integr ; 19(1): 4716, 01 Fevereiro 2019. tab
Article in English | LILACS, BBO | ID: biblio-998227

ABSTRACT

Objective: To qualitatively investigate whether a prototype brush composed of metal bristles collects oral epithelial cells effectively for cytological evaluation of oral mucosal lesions. Material and Methods: Twenty patients with suspicious oral mucosal lesions were enrolled. Patients were asked to gargle with saline and to deposit the oral rinse into specimen cup. Then, oral mucosal cell samples were collected using a metal oral brush, via sweeping motion. Punch biopsy was performed for histological examination. All samples were evaluated with liquid based cytology (LBC) according to the cellularity, the depth of the epithelial layer, cellular integrity by an oral pathologist. Results: Oral rinse provided samples with 100% cellular integrity and cellularity, mostly from the intermediary layers. With metal brush, both inadequate cellularity and cellular integrity was observed in 25% of the cases. Cellular integrity was adequate in 65%, cellularity was adequate in 45% of the lesions. Samples were dominantly from the intermediary layers, but in one case, metal brush collected cells from the parabasal layer. Conclusion: The narrow spiral pitch and width of metal bristles may have resisted to release the cellular samples collected. With adjustment of the spiral pitch and diameter of metal brush bristles, its' efficacy could be enhanced.


Subject(s)
Humans , Biopsy , Mouth Neoplasms/diagnosis , Early Diagnosis , Mouth Mucosa/pathology , Turkey , Cytological Techniques/methods , Cytodiagnosis
17.
Rev. bras. cancerol ; 65(4)20191216.
Article in Portuguese | LILACS | ID: biblio-1048719

ABSTRACT

Introdução:Tem-se apontado a persistência de desigualdades raciais na acessibilidade a bens e serviços de saúde, estando o indivíduo com câncer inserido nesse contexto. Objetivo: Analisar os fatores que impactam a acessibilidade da população negra ao cuidado oncológico no Brasil. Método: Por meio de uma revisão integrativa da literatura, buscaram-se, nas bases PubMed, LILACS e Embase, artigos originais publicados em português, inglês e espanhol sem limite temporal. Resultados: Foram incluídos 13 artigos, analisados a partir do tipo de câncer abordado: câncer de mama, câncer ginecológico, câncer de próstata e câncer de cavidade oral. Conclusão: As desigualdades raciais e socioeconômicas refletem nas ações de acessibilidade ao cuidado oncológico, maioritariamente na detecção precoce. Independentemente do tipo de câncer e das formas de diagnóstico e de tratamento, é inegável a dificuldade do paciente negro aos cuidados oncológicos por razões de natureza social e econômica.Os profissionais de saúde deveriam assegurar o atendimento à população negra ao mesmo nível prestado aos demais grupos sociais para garantir e superar as barreiras de acesso aos bens e serviços de saúde.


Introduction: The persistence of racial inequalities in the access to health services has been pointed out and the individual with cancer is within this scenario. Objective: To analyze the factors that impact the accessibility of the black population to cancer care in Brazil. Method: Through an integrative literature review, it were searched original articles published in Portuguese, English and Spanish in the databases PubMed, LILACS and Embase without time limitation. Results: Thirteen articles were included and analyzed based in the type of cancer addressed: breast cancer, gynecological cancer, prostate cancer and oral cancer. Conclusion: The racial and socioeconomic inequalities reflect upon the actions of accessibility to cancer care, mostly in early detection. Regardless of the type of cancer and the forms of diagnosis and treatment, it is unquestionable the difficulty the afro-descendant population has to access oncological care because of social and economic issues. Healthcare providers must ensure the care to the afro-descendant population as much as they do with other social groups to overcome the barriers to access health services.


Introducción: Se ha señalado la persistencia de las desigualdades racial e la accesibilidad a los bienes y servicios de salud, con el individuo con cáncer insertado en este contexto. Objetivo: Analizar los factores que afectan la accesibilidad de la población negra a la atención del cáncer en Brasil. Método: A través de una revisión bibliográfica integradora, se realizar búsquedas en las bases de datos PubMed, LILACS e Embase artículos originales publicados en portugués, inglés y español sin límite de tiempo. Resultados: Se incluyeron 13 artículos, analizado sen función del tipo de cáncer abordado: cáncer de mama, cáncer ginecológico, cáncer de próstata y cáncer de cavidad oral. Conclusión: Las desigualdades raciales y socioeconómicas se reflejan en las acciones de accesibilidad a la atención del cáncer, principalmente en la detección temprana. Independientemente del tipo de cáncer y las formas de diagnóstico y tratamiento, la dificultad del paciente negro en la atención del cáncer es innegable por razones sociales y económicas. Los profesionales de la salud deben garantizar la atención de la población negra al mismo nivel que otros grupos sociales para garantizar y superar las barreras de acceso a los bienes y servicios de salud.


Subject(s)
Humans , Male , Female , African Continental Ancestry Group , Health Services Accessibility , Neoplasms/diagnosis , Prostatic Neoplasms/diagnosis , Socioeconomic Factors , Brazil , Breast Neoplasms/diagnosis , Mouth Neoplasms/diagnosis , Health of Ethnic Minorities , Race Factors , Genital Neoplasms, Female/diagnosis , Neoplasms/therapy
18.
Einstein (Säo Paulo) ; 17(2): eRC4624, 2019. graf
Article in English | LILACS | ID: biblio-1001899

ABSTRACT

ABSTRACT Oral squamous papilloma is a benign tumor whose pathogenesis has been associated with human papillomavirus infection. Thus, it is noteworthy that human papillomavirus infection is one of the risk factors associated with the development of cervical, anogenital, pharynx, larynx and oral cavity carcinomas. Oral squamous papilloma can affect any region of the oral cavity, and transmission of human papillomavirus can occur by direct contact, sexual intercourse or from mother to child during delivery. The diagnosis is clinical and histopathological, with surgical removal representing the treatment of choice. Recently, widefield optical fluorescence has been used as a complementary examination to the conventional clinical examination in the screening of oral pathological lesions and for the delimitation of surgical margins. We report a case of oral squamous papilloma with its clinical, histopathological features and, in addition, from the perspective of wide field optical fluorescence.


RESUMO O papiloma escamoso oral é um tumor benigno, cuja patogênese tem sido associada à infecção pelo papilomavírus humano. A infecção pelo papilomavírus humano é um dos fatores de risco associado ao desenvolvimento dos carcinomas cervicais, anogenitais, faríngeos, laríngeos e da cavidade oral. O papiloma escamoso oral pode acometer qualquer região da cavidade oral, e a transmissão do papilomavírus humano ocorre por contato direto, relação sexual ou de mãe para filho durante o parto. O diagnóstico é clínico e histopatológico, e a remoção cirúrgica representa o tratamento de escolha. Recentemente, a fluorescência óptica de campo amplo tem sido empregada como exame complementar ao exame clínico convencional, no rastreio de lesões patológicas orais e para delimitação de margens cirúrgicas. Relatamos um caso de papiloma escamoso oral com suas características clínicas e histopatológicas, sob a perspectiva da fluorescência óptica de campo amplo.


Subject(s)
Humans , Male , Papilloma/diagnosis , Mouth Neoplasms/diagnosis , Neoplasms, Squamous Cell/diagnosis , Papilloma/pathology , Mouth Neoplasms/pathology , Neoplasms, Squamous Cell/pathology , Palate, Hard , Fluorescence , Middle Aged
19.
Braz. oral res. (Online) ; 33: e043, 2019. tab, graf
Article in English | LILACS | ID: biblio-1001605

ABSTRACT

Abstract: Proteomic techniques have become popular in medicine and dentistry because of their widespread use in analyzing bodily fluids such as blood, saliva, urine, and gingival crevicular fluids as well as hard tissues such as enamel, dentine, and cementum. This review is a guide to proteomic techniques in general dentistry, summarizing techniques and their clinical application in understanding and diagnosing diseases and their use in identifying biomarkers of various diseases.


Subject(s)
Humans , Saliva/chemistry , Sjogren's Syndrome/diagnosis , Proteome , Proteomics/methods , Salivary Proteins and Peptides/chemistry , Mass Spectrometry/methods , Mouth Neoplasms/diagnosis , Biomarkers/chemistry , Electrophoresis, Polyacrylamide Gel
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