Meta-analysis of acupuncture and moxibustion for the therapeutic effect on postoperative gastrointestinal dysfunction of gastric cancer / 中国针灸

OBJECTIVE@#To systematically review the therapeutic effect of acupuncture and moxibustion on postoperative gastrointestinal dysfunction (GID) of gastric cancer with meta-analysis.@*METHODS@#The articles of randomized controlled trials (RCTs) of acupuncture and moxibustion treatment for postoperative GID of gastric cancer were retrieved from the following databases from the time of database establishment to December 31, 2020, including PubMed, EMbase, Cochrane Central Register of Controlled Trials (CENTRAL), China National Knowledge Infrastructure (CNKI), Wanfang database, VIP database and China Biomedical Literature Database (SinoMed). RevMan5.3 software was used for meta-analysis. Using Stata16.0 software, sensitivity analysis and publication bias test were performed.@*RESULTS@#A total of 16 RCTs were included finally, including 1 360 patients, of which, there were 681 cases in the intervention group and 679 cases in the control group. Meta-analysis results showed that acupuncture and moxibustion shortened the time of first flatus (P<0.000 01, MD =-14.52, 95%CI = [-17.31, -11.74]), the time of first bowel sound (P<0.000 01, MD =-10.50, 95%CI =[-13.99, -7.01]) and the time of first defecation (P<0.000 1, MD =-13.79, 95%CI =[-20.09, -7.50]). Meanwhile, acupuncture and moxibustion shortened the time of the first food intake (P<0.000 1, MD =-3.23, 95%CI = [-3.45, -3.00]) and the hospital stay (P<0.000 01, MD =-1.94, 95%CI =[-2.20, -1.69]) after gastric cancer operation, and reduced the incidences of postoperative adverse reactions, i.e. nausea and vomiting (P =0.000 3, RR =0.43, 95%CI =[0.28, 0.68]) and abdominal distention (P =0.000 5, RR =0.41, 95%CI =[0.25, 0.68]).@*CONCLUSION@#Acupuncture and moxibustion can promote the recovery of postoperative gastrointestinal function in the patients with gastric cancer. But, for the comparison among different measures of acupuncture and moxibustion intervention, it needs more high-quality trials for a further verification.

Discussion on the essential thought of Ma's warm moxibustion technique for "unblocking fu-organs" / 中国针灸

"Unblocking fu organs" is one of the essential principles of Ma's warm moxibustion technique, characterized as "dredging" and "harmonizing" for either deficiency or excess condition. Under the guidance of this therapeutic thought, the acupoints for moxibustion are mainly selected from the middle and lower parts of the body. Regarding the therapeutic approach, the acupoint prescription for moxibustion should be formed in line with warming and promoting circulation of fu organs; the moxibustion degree should be specially considered, in which, the mild moxibustion is recommended to induce promoting action; and the systematic moxibustion technique should be the root for dredging fu organs and regulating zang organs. Ma's mild moxibustion technique stresses on removing the obstruction of fu organs and emphasizes promoting the qi activity of sanjiao (triple energizer) and regulating the balance of five zang organs.

Effect of moxibustion on quality of life in tumor patients: network Meta-analysis / 中国针灸

OBJECTIVE@#To rank the effectiveness of various moxibustion methods on the quality of life in tumor patients, and explore the best treatment plan of moxibustion for improving the quality of life in tumor patients from the perspective of evidence-based medicine.@*METHODS@#The Chinese and English literature of randomized controlled trial (RCT) of the effect of moxibustion on the quality of life in tumor patients were searched in PubMed, EMbase, Cochrane Library, CNKI, SinoMed, Wanfang and VIP. The retrieval time was from the establishment of the databases to October 31, 2020. The R3.6.2 and Stata15.0 software were used for network Meta-analysis based on Bayesian model.@*RESULTS@#A total of 30 Chinese RCTs were included, including 2 169 patients, involving 16 interventions. In terms of the effectiveness of improving quality of life, the top three treatments were special moxibustion plus other therapies 1 (either of tendon acupuncture, acupoint pressing, acupoint injection, etc.), wheat-grain moxibustion and mild moxibustion. The special moxibustion methods were the combination of fire-dragon moxibustion, thunder-fire moxibustion, fuyang fire moxibustion and moxa salt-bag moxibustion. The number of literature of these four moxibustion methods was small. Considering the clinical application of moxibustion, it was concluded that wheat-grain moxibustion ranked first.@*CONCLUSION@#The adjuvant treatment of wheat-grain moxibustion is more effective than other moxibustion methods on improving the quality of life in tumor patients, but the results needed to be further verified because the bias risk of RCT included in this study is high and the sample size is small.

Effect of moxibustion on M2 and P2X3 receptors of bladder tissue in rats with neurogenic bladder of detrusor areflexia after lumbar-sacral spinal cord injury / 中国针灸

OBJECTIVE@#To observe the effect of moxibustion at "Guanyuan" (CV 4) and "Shenque" (CV 8) on acetylcholine (Ach), adenosine triphosphate (ATP) and muscarinic-type choline receptor (M2) and purine receptor P2X3 in bladder tissue in the rats with neurogenic bladder (NB) of detrusor areflexia after lumbar-sacral spinal cord injury and explore the underlying mechanism of moxibustion for promoting detrusor contraction.@*METHODS@#Sixty SD rats were randomly divided into a model preparation group (n=45) and a sham-operation group (n=15). In the model preparation group, the modified Hassan Shaker spinal cord transection method was used to prepare the model of NB. In the sham-operation group, the spinal cord transection was not exerted except laminectomy and spinal cord exposure. Among the rats with successfully modeled, 30 rats were selected and divided randomly into a model group and a moxibustion group, with 15 rats in each one. On the 15th day after the operation, moxibustion was applied at "Guanyuan" (CV 4) and "Shenque" (CV 8) in the moxibustion group, 10 min at each acupoint, once a day. The consecutive 7-day treatment was as one course and the intervention for 2 courses was required. Urodynamic test was adopted to evaluate bladder function in rats. Using HE staining, the morphological changes in bladder tissue were observed. The content of Ach and ATP in bladder tissue was measured with biochemical method, and the protein and mRNA expression levels of M2 and P2X3 receptors in bladder tissue were detected with Western blot and real-time fluorescence quantification PCR method.@*RESULTS@#Compared with the sham-operation group, the maximum bladder capacity, leakage point pressure and bladder compliance were increased in the rats of the model group (P<0.05). Compared with the model group, the maximum bladder capacity, the leakage point pressure and bladder compliance were decreased in the rats of the moxibustion group (P<0.05). In the model group, the detrusor fibres were arranged irregularly, bladder epithelial tissues were not tightly connected and cell arrangement was disordered, combined with a large number of vacuolar cells. In the moxibustion group, compared with the model group, the detrusor fibres were arranged regularly, bladder epithelial cells were well distributed and vacuolar cells were reduced. Compared with the sham-operation group, the content of Ach and ATP in bladder tissue was decreased (P<0.05), the protein and mRNA expression levels of M2 and P2X3 receptors were reduced (P<0.05) in the model group. In the moxibustion group, the content of Ach and ATP in bladder tissue was increased (P<0.05) and the protein and mRNA expression levels of M2 and P2X3 receptors were increased (P<0.05) as compared with the model group.@*CONCLUSION@#Moxibustion at "Guanyuan" (CV 4) and "Shenque" (CV 8) may effectively improve bladder function in the rats with NB of detrusor areflexia after lumbar-sacral spinal cord injury and its underlying mechanism is related to promoting the release of Ach and up-regulating the expression of M2 receptor, thereby enhancing the release of ATP and increasing the expression of P2X3 receptor. Eventually, detrusor contraction is improved.

Technical recommendations for pragmatic randomized controlled trials of heat-sensitive moxibustion in community (Ⅱ): organization, implementation and follow-up visits / 中国针灸

Based on the community research experience of heat-sensitive moxibustion, this study explained technical recommendations for pragmatic randomized controlled trials (pRCTs) of heat-sensitive moxibustion in community from 7 aspects: selection of community research sites, ethical approval and registration, patient recruitment, training of standard operating procedures, ensuring patient compliance, quality control of follow-up visits and patient safety, which aimed to reduce the difficulty of research execution and improve the quality of pRCTs implementation and follow-up visits of heat-sensitive moxibustion.

Finite element analysis method and optimization of flexible ginger moxibustion based on Abaqus and Taguchi method / 生物医学工程学杂志

Ginger moxibustion has the effect of regulating zang-fu organs and activating qi and blood circulation. When used, ginger paste is required to be close to human skin. Currently, the ginger box used clinically in the hospital can't meet the requirement of large area fitting human skin, and the efficacy of ginger moxibustion is significantly reduced. In this study, a flexible ginger paste box was proposed, which was composed of flexible components polydimethylsiloxane (PDMS), spring and wire netting. The large flexibility of the structure made it fit well with human skin. Finite element method was used to study the fitting degree between ginger paste box and waist soft tissue. Finite element models of flexible ginger paste box and waist soft tissue were established based on Hypermesh and Abaqus software. The equivalent contact area between the flexible ginger paste box and waist was obtained by numerical simulation under different PDMS unilateral thickness, spring wire diameter, wire netting diameter and ginger paste layer thickness. The four parameters were taken as the influencing factors, and the equivalent contact area was taken as the optimization objective. The typical value analysis and variance analysis of S/N were performed by Taguchi method, and the results showed that among the four influencing factors, the wire netting diameter had the largest influence on equivalent contact area and its contribution rate reached 41.98%. The contribution rates of PDMS unilateral thickness, spring wire diameter and ginger paste layer thickness reached 36.48%, 13.97% and 6.50%, respectively. The optimized PDMS unilateral thickness, spring wire diameter, wire netting diameter and ginger paste layer thickness were 1.5, 0.4, 0.15, 35 mm, respectively, and the equivalent contact area was 95.60 cm 2. The optimized flexible ginger paste box with great fitting performance can improve the effect of ginger moxibustion.

Tratamiento con moxibustión en los pacientes con sacrolumbalgia aguda / Moxibustion treatment in pacient with acute sacrolumbalgy

Se realizó un estudio observacional, descriptivo y longitudinal sobre la evolución del tratamiento con moxibustión en 150 pacientes con sacrolumbalgia aguda que fueron diagnosticados en la consulta de Medicina natural y tradicional (MNT) del Policlínico Mantilla, durante el primer semestre del año 2008, con el objetivo de determinar su estado evolutivo según criterio clínico al cabo de la décima sesión, caracterizarlos en cuanto a edad, sexo y ocupación, y describir las manifestaciones clínicas de interés antes de someterse a la primera sesión y después de culminada la última. Se midieron las variables: edad, sexo, ocupación, realización de esfuerzo físico, dolor, intensidad, inflamación e irradiación. Se realizaron entrevistas para corroborar los aspectos cualitativos en la aplicación del tratamiento empleado y con los datos obtenidos se confeccionaron tablas para su mejor comprensión. Como resultado más relevante se obtuvo que 90 por ciento de los pacientes que llegaron a la consulta con dolor, refirieran no sentir dolor alguno al finalizar el tratamiento. Los resultados que se derivan de esta investigación se están utilizando en la preparación y actualización del personal médico y de enfermería en la Atención Primaria de Salud(AU)

It was carried out an observational, descriptive and longitudinal study on the evolution of the treatment with moxibustion in 150 patients with sharp sacrolumbalgy that were diagnosed in the consultation of natural and traditional Medicine of the Policlinic Mantilla, during the first semester of the year 2008 with the objective of determining their evolutionary state according to clinical approach after the tenth session, to characterize them as for age, sex and occupation, and to describe the clinical manifestations of interest before undergoing the first session and after having culminated the last one. The variables were measured: age, sex, and occupation, realization of physical effort, pain, intensity, inflammation and irradiation. They were carried out interviews to corroborate the qualitative aspects in the application of the used treatment and with the obtained data charts were made for their best understanding. As a result more excellent it was obtained that 90 percent of the patients that arrived to the consultation with pain, referred not to feel pain some when concluding the treatment. The results that they are derived of this investigation they are using in the preparation and the medical personnel's bring up to date and of infirmary in the primary attention of health(AU)

Tratamiento con Moxibustión en el Síndrome Bi de hombro / Moxibustion treatment in Bi Syndrome of the shoulder

En este estudio se seleccionaron 30 pacientes con el diagnóstico de bursitis aguda de hombro no traumática compatible con un síndrome Bi por frío en medicina tradicional asiática, que acudieron al cuerpo de guardia del Instituto Superior de Medicina Mlitar (ISMM) Luis Díaz Soto en el período comprendido de julio de 1998 a noviembre de 1999. A los mismos se les realizó un diagnóstico tradicional así como una valoración cualitativa del dolor y la movilidad articular antes y después de recibir el tratamiento con moxibustión. Se realizó un estudio prospectivo observacional analítico y se le aplicó el test de Wilcoxon. Todo se realizó con un nivel de significación µ = 0,05 (con un 95 de compatibilidad). Se hizo una evaluación de la respuesta terapéutica, comprobándose la efectividad de la moxibustión en el hombro doloroso, por lo que hubo modificación del dolor en la mayoría de los casos, aumentando el ángulo de abducción la mayor cantidad de pacientes, terminando con evolución satisfactoria el 83,33 de los casos.

We chose 30 patients diagnosed with non-traumatic acute bursitis of the shoulder, compatible with a Bi Syndrome by cold in Asiatic Traditional Medicine, assisting the High Institute of Military Medicine Luis Díaz Soto from July 1998 to November 1999. They were diagnozed in traditional way, and pain and articular mobility were qualitative evaluated before and after being treated with moxibustion. An analitic, observational, prospective study was carried out and the Wilcoxon´s test was applied. Everithing was made with a signification level ? = 0,05 (95 percent of compatibility). We evaluated the therapeutic answer, proving the efectiveness of moxibustion in painly shoulder. There was a pain modification in most of the cases; in most of the patients the abduction angle was increased. 83.33 percent of the cases showed a satisfactory evolution.

Tratamiento de la enuresis con moxa en niños. Cárdenas 2003-2004 / The enuresis treatment with moxa in children. Cárdenas 2003-2004

La enuresis es uno de los problemas más desconcertantes en la consulta del pediatra y el médico general integral. La bibliografía revisada plantea que ésta resuelve, en algunos casos, con la terapia occidental, aunque esta última ha perdido valor, porque un por ciento no soluciona el problema. Se ha aplicado la Medicina Natural y Tradicional (MNT) en diferentes formas y ha resultado eficaz en la eliminación de la enuresis. Se realizó un estudio prospectivo, longitudinal, con los pacientes que presentaron enuresis del policlínico José Antonio Echeverría, de Cárdenas, durante el año 2003. Hicimos un estudio para comparar los resultados obtenidos con los dos tipos de tratamiento; precisar el umbral de sensibilidad a la exposición de la moxa y determinar el tiempo más efectivo de tratamiento para la eliminación de la enuresis. Se escogieron 25 niños de 5 a 14 años de forma aleatoria como muestra, se dividieron en tres grupos, por condiciones del local, y se aplicó moxa indirecta. Todos estos niños fueron tratados previamente con terapia occidental. Los resultados obtenidos con ambos tratamientos, recogidos de las historias clínicas, fueron procesados en una Pentium 4 utilizando frecuencia absoluta y frecuencia porcentual. Encontramos que los niños de piel más oscura resisten más tiempo el calor, mayor frecuencia de la enuresis en el sexo masculino, una buena respuesta al tratamiento, con desaparición o mejoría de la misma al aplicar la moxibustión, en un período más corto que cuando se usa la terapia occidental en todos los casos estudiados.

The enuresis is one of the most disconcerting problems at the paediatric and integral general doctor's consult. The reviewed bibliography states that this is solved, in some cases, with the western therapy, although this therapy has lost value, because it does not solve the problem in some percentage of cases. Natural and traditional medicine has being applied in different ways, and it has being efficacious in the enuresis elimination. We made a longitudinal, prospective study of the patients presenting enuresis at the policlinic “José Antonio Echeverría”, of Cárdenas, during 2003. We made a study to compare the obtained results with both kinds of treatment; to precise the sensibility threshold to the moxa exposition and to determine the most effective treatment time for the enuresis elimination. As sample we chose 25 5-to-14-years-old children, divided in three groups, in dependence of the treatment place. Indirect moxa was applied. All of these children were previously treated with western therapy. The obtained results with both treatments, registered in the clinical records, were processed in a Pentium 4, using absolute and percentage frequency. We found that darker skin children resist heat more time; enuresis is more frequently in male sex; a good answer to the treatment, with enuresis disappearing or bettering when applying moxibustion, in a shorter period than when the western therapy is used in all the studied cases.